CN116636613A - Formula food with full nutrition and special medical application as well as preparation method and application thereof - Google Patents
Formula food with full nutrition and special medical application as well as preparation method and application thereof Download PDFInfo
- Publication number
- CN116636613A CN116636613A CN202310421131.6A CN202310421131A CN116636613A CN 116636613 A CN116636613 A CN 116636613A CN 202310421131 A CN202310421131 A CN 202310421131A CN 116636613 A CN116636613 A CN 116636613A
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- Prior art keywords
- parts
- vitamin
- powder
- special medical
- vegetable oil
- Prior art date
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- Pending
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- 235000016709 nutrition Nutrition 0.000 title claims abstract description 29
- 230000035764 nutrition Effects 0.000 title claims abstract description 24
- 235000013305 food Nutrition 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 239000000843 powder Substances 0.000 claims abstract description 63
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 44
- 239000008158 vegetable oil Substances 0.000 claims abstract description 44
- 239000003094 microcapsule Substances 0.000 claims abstract description 38
- 239000000284 extract Substances 0.000 claims abstract description 31
- 235000015097 nutrients Nutrition 0.000 claims abstract description 25
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims abstract description 20
- 235000015872 dietary supplement Nutrition 0.000 claims abstract description 18
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 16
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 16
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 16
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 16
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 16
- 229940088594 vitamin Drugs 0.000 claims abstract description 16
- 229930003231 vitamin Natural products 0.000 claims abstract description 16
- 235000013343 vitamin Nutrition 0.000 claims abstract description 16
- 239000011782 vitamin Substances 0.000 claims abstract description 16
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 15
- 235000010755 mineral Nutrition 0.000 claims abstract description 15
- 239000011707 mineral Substances 0.000 claims abstract description 15
- 244000077995 Coix lacryma jobi Species 0.000 claims abstract description 12
- 240000004371 Panax ginseng Species 0.000 claims abstract description 12
- 235000002789 Panax ginseng Nutrition 0.000 claims abstract description 12
- 235000008434 ginseng Nutrition 0.000 claims abstract description 12
- 229920001202 Inulin Polymers 0.000 claims abstract description 11
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 claims abstract description 11
- 229940029339 inulin Drugs 0.000 claims abstract description 11
- 241000195493 Cryptophyta Species 0.000 claims abstract description 10
- 240000008042 Zea mays Species 0.000 claims abstract description 10
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims abstract description 10
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 10
- 229940114079 arachidonic acid Drugs 0.000 claims abstract description 10
- 235000021342 arachidonic acid Nutrition 0.000 claims abstract description 10
- 235000005822 corn Nutrition 0.000 claims abstract description 10
- 235000021323 fish oil Nutrition 0.000 claims abstract description 10
- 235000021255 galacto-oligosaccharides Nutrition 0.000 claims abstract description 10
- 150000003271 galactooligosaccharides Chemical class 0.000 claims abstract description 10
- 239000003921 oil Substances 0.000 claims abstract description 10
- 235000019198 oils Nutrition 0.000 claims abstract description 10
- 239000006188 syrup Substances 0.000 claims abstract description 10
- 235000020357 syrup Nutrition 0.000 claims abstract description 10
- 150000003722 vitamin derivatives Chemical class 0.000 claims abstract description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 52
- 150000001875 compounds Chemical class 0.000 claims description 24
- 238000002156 mixing Methods 0.000 claims description 21
- 229930003270 Vitamin B Natural products 0.000 claims description 19
- 235000019156 vitamin B Nutrition 0.000 claims description 19
- 239000011720 vitamin B Substances 0.000 claims description 19
- -1 vitamin compound Chemical class 0.000 claims description 17
- 239000007788 liquid Substances 0.000 claims description 15
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 claims description 15
- 235000018102 proteins Nutrition 0.000 claims description 15
- 238000005507 spraying Methods 0.000 claims description 15
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 14
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 14
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 12
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims description 12
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 12
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 12
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 12
- 239000011738 major mineral Substances 0.000 claims description 12
- 235000011963 major mineral Nutrition 0.000 claims description 12
- 239000011573 trace mineral Substances 0.000 claims description 12
- 235000013619 trace mineral Nutrition 0.000 claims description 12
- 102000011632 Caseins Human genes 0.000 claims description 11
- 108010076119 Caseins Proteins 0.000 claims description 11
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 10
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 10
- 239000000839 emulsion Substances 0.000 claims description 10
- 239000011780 sodium chloride Substances 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 10
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000000605 extraction Methods 0.000 claims description 9
- 239000003995 emulsifying agent Substances 0.000 claims description 8
- FTSSQIKWUOOEGC-RULYVFMPSA-N fructooligosaccharide Chemical compound OC[C@H]1O[C@@](CO)(OC[C@@]2(OC[C@@]3(OC[C@@]4(OC[C@@]5(OC[C@@]6(OC[C@@]7(OC[C@@]8(OC[C@@]9(OC[C@@]%10(OC[C@@]%11(O[C@H]%12O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%12O)O[C@H](CO)[C@@H](O)[C@@H]%11O)O[C@H](CO)[C@@H](O)[C@@H]%10O)O[C@H](CO)[C@@H](O)[C@@H]9O)O[C@H](CO)[C@@H](O)[C@@H]8O)O[C@H](CO)[C@@H](O)[C@@H]7O)O[C@H](CO)[C@@H](O)[C@@H]6O)O[C@H](CO)[C@@H](O)[C@@H]5O)O[C@H](CO)[C@@H](O)[C@@H]4O)O[C@H](CO)[C@@H](O)[C@@H]3O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O FTSSQIKWUOOEGC-RULYVFMPSA-N 0.000 claims description 8
- 229940107187 fructooligosaccharide Drugs 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 8
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 7
- 235000010216 calcium carbonate Nutrition 0.000 claims description 7
- 229910000365 copper sulfate Inorganic materials 0.000 claims description 7
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 claims description 7
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 claims description 7
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical compound [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 claims description 7
- 239000011706 ferric diphosphate Substances 0.000 claims description 7
- 235000007144 ferric diphosphate Nutrition 0.000 claims description 7
- CADNYOZXMIKYPR-UHFFFAOYSA-B ferric pyrophosphate Chemical compound [Fe+3].[Fe+3].[Fe+3].[Fe+3].[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O CADNYOZXMIKYPR-UHFFFAOYSA-B 0.000 claims description 7
- 229940036404 ferric pyrophosphate Drugs 0.000 claims description 7
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims description 7
- 239000001095 magnesium carbonate Substances 0.000 claims description 7
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims description 7
- 235000014380 magnesium carbonate Nutrition 0.000 claims description 7
- 229940099596 manganese sulfate Drugs 0.000 claims description 7
- 239000011702 manganese sulphate Substances 0.000 claims description 7
- 235000007079 manganese sulphate Nutrition 0.000 claims description 7
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 claims description 7
- 239000001103 potassium chloride Substances 0.000 claims description 7
- 235000011164 potassium chloride Nutrition 0.000 claims description 7
- 239000001509 sodium citrate Substances 0.000 claims description 7
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 7
- 239000011781 sodium selenite Substances 0.000 claims description 7
- 235000015921 sodium selenite Nutrition 0.000 claims description 7
- 229960001471 sodium selenite Drugs 0.000 claims description 7
- WGIWBXUNRXCYRA-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WGIWBXUNRXCYRA-UHFFFAOYSA-H 0.000 claims description 7
- 239000011746 zinc citrate Substances 0.000 claims description 7
- 235000006076 zinc citrate Nutrition 0.000 claims description 7
- 229940068475 zinc citrate Drugs 0.000 claims description 7
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 6
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims description 6
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 6
- 102000014171 Milk Proteins Human genes 0.000 claims description 6
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- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 6
- 229930003268 Vitamin C Natural products 0.000 claims description 6
- 229930003316 Vitamin D Natural products 0.000 claims description 6
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 6
- 102000007544 Whey Proteins Human genes 0.000 claims description 6
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- 239000011575 calcium Substances 0.000 claims description 6
- 229910052791 calcium Inorganic materials 0.000 claims description 6
- 235000001465 calcium Nutrition 0.000 claims description 6
- 239000005018 casein Substances 0.000 claims description 6
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims description 6
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pediatric Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The application discloses a formula food with full nutrition and special medical application, a preparation method and application thereof, and a nutrition supplementing reinforcing agent comprises maltodextrin, corn syrup, fructo-oligosaccharides, galacto-oligosaccharides, inulin, protein complex, vegetable oil microcapsule powder, DHA algae oil powder, arachidonic acid powder, fish oil microcapsule powder, vitamin complex and mineral complex. The vegetable oil microcapsule powder contains extracts of Korean ginseng, dangshen and coix seed, and the three substances act together to regulate intestines and stomach and improve intestines and stomach functions, so that the absorption of intestines and stomach to nutrient substances is promoted, and the absorption and utilization rate of the nutrition supplement reinforcing agent is improved. The total nutrient special medical use formula food contains various components, can provide sufficient nutrient substances, can supplement nutrition required by people of 1-10 years old, and is a total nutrient supplement with higher nutritional value.
Description
Technical Field
The application belongs to the technical field of nutritional preparations, and particularly relates to a nutritional supplement enhancer, a preparation method and application thereof.
Background
Malnutrition is a term describing health conditions and is caused by improper or inadequate diet, generally referred to as malnutrition resulting from insufficient intake, malabsorption or excessive loss of nutrients, but may also include overnutrition resulting from overeating or excessive intake of specific nutrients, and if a healthy diet consisting of an appropriate amount, type or quality of nutrients cannot be taken for a long period of time, the individual will be malnourished, and the long period of malnutrition may lead to starvation death, and the long period of malnutrition is the main cause of malnutrition, which is a major hazard to children:
1. in the early stage of malnutrition, the height has no influence, but as the illness state is aggravated, the bone growth is slowed down, the height is lower than normal, the mild malnutrition and the mental state are normal, but the severe state can be listlessness, poor response, low body temperature, thin and weak pulse, no appetite, diarrhea and constipation alternation, when the plasma albumin is obviously reduced, the blood albumin can be combined, the skin is shiny, the chronic ulcer can be formed by the collapse and infection in severe cases, and the severe malnutrition can have important viscera function damage, such as heart function reduction can be heart sound hypoplasia, blood pressure is low, pulse is slow, and the respiratory superficial is and the like;
2. because of the hypoimmunity of the children suffering from malnutrition, the children are susceptible to various infections such as recurrent respiratory tract infection, thrush, pneumonia, tuberculosis, tympanitis, urinary tract infection and the like; the diarrhea of the infant often persists without increasingly heavy malnutrition to form a vicious circle, the malnutrition can be accompanied by spontaneous hypoglycemia, the infant can suddenly appear as pale complexion, unclear mind, slow pulse, apnea, non-rising body temperature but no convulsion, if the infant is not diagnosed in time, death can be caused, and the 'homology of medicine and food' is one of the most valuable contributions to human beings in Chinese original medicine; traditional Chinese medicine emphasizes that "medical therapy is inferior to dietary therapy", and dietary therapy becomes the best choice for modern pursuing the return of uncut and true healthy diet; people can remove the pain in the process of enjoying food, avoid injection and medicine taking, and even the bitter of operation.
Currently, researchers have developed a number of nutritional supplement products that are specific to children. For example, the prior art discloses a children granule for enhancing immunity, which is prepared from whole milk powder, enzymolysis bone powder, lactoferrin, fructose, inulin, isomaltulose, egg yolk powder, instant coconut powder, colostrum basic protein, hydrolyzed egg yolk powder and compound nutrients; the prior art also discloses a compound vitamin tablet suitable for children under 10 years old, which comprises the following components: beta-carotene, vitamin C, vitamin D, vitamin B1, riboflavin, nicotinic acid, pantothenic acid, vitamin B6, biotin, folic acid, vitamin B12, calcium, iron, zinc and auxiliary materials.
As is clear from this, many nutritional supplements specific to children are available in the prior art, but the children have weak gastrointestinal functions, and cannot absorb the nutrients in the nutritional supplements effectively, so that the nutritional supplement effect of the nutritional supplements is not fully reflected.
Disclosure of Invention
Aiming at the prior art, the application provides a nutrition supplementing reinforcing agent to solve the problem that a consumer, especially children, can not thoroughly absorb the nutrition substances in the nutrition supplementing agent.
In order to achieve the aim, the technical scheme adopted by the application is to provide a formula food with full nutrition and special medical use, which comprises maltodextrin, corn syrup, fructo-oligosaccharides, galacto-oligosaccharides, inulin, protein complex, vegetable oil microcapsule powder, DHA algae oil powder, arachidonic acid powder, fish oil microcapsule powder, vitamin complex and mineral complex;
the vegetable oil microcapsule powder is prepared through the following steps:
s1: respectively carrying out alcohol extraction on Korean ginseng, dangshen and coix seed, then mixing the alcohol extracts of the Korean ginseng, the dangshen and the coix seed according to the mass ratio of 2-5:1-3:1-3, and then co-dissolving the mixture with maltodextrin, sodium caseinate, sodium tripolyphosphate and sucrose fatty acid ester according to the mass ratio of 3-5:10-15:15-20:1-3:1-2:0.5-2 in water to obtain emulsion;
s2: adding an emulsifying agent into the vegetable oil, and stirring for 10-20 min at room temperature at a rotating speed of 100-150 rpm to obtain emulsified vegetable oil;
s3: adding the emulsified vegetable oil into the emulsion under the stirring condition, and standing and emulsifying for 1-3 h at 50-60 ℃ after the addition;
s4: and (3) spray drying the feed liquid subjected to standing emulsification to obtain the vegetable oil microcapsule powder.
On the basis of the technical scheme, the application can be improved as follows.
Further, the nutrition supplementing and reinforcing agent comprises the following components in parts by mass:
25-100 parts of maltodextrin, 0-50 parts of corn syrup, 0-20 parts of fructo-oligosaccharide, 0-30 parts of galacto-oligosaccharide, 0-5 parts of inulin, 20-100 parts of protein compound, 10-80 parts of vegetable oil microcapsule powder, 0-10 parts of DHA algae oil powder, 0-10 parts of arachidonic acid powder, 0-20 parts of fish oil microcapsule powder, 0-10 parts of vitamin compound and 0-20 parts of mineral compound.
Further, the nutrition supplementing and reinforcing agent comprises the following components in parts by mass:
60 parts of maltodextrin, 25 parts of corn syrup, 5 parts of fructo-oligosaccharide, 13 parts of galacto-oligosaccharide, 1 part of inulin, 60 parts of protein compound, 45 parts of vegetable oil microcapsule powder, 5 parts of DHA algae oil powder, 5 parts of arachidonic acid powder, 10 parts of fish oil microcapsule powder, 5 parts of vitamin compound and 10 parts of mineral compound.
Further, the protein complex comprises the following components in parts by mass:
5-80 parts of whey protein, 5-25 parts of soybean protein isolate, 3-50 parts of casein and 5-15 parts of milk protein isolate.
Further, the protein complex comprises the following components in parts by mass:
40 parts of whey protein, 15 parts of soy protein isolate, 25 parts of casein and 10 parts of milk protein isolate.
Further, the vitamin complex comprises the following components in parts by mass:
5-10 parts of vitamin A, 3-6 parts of vitamin D, 2-5 parts of vitamin E, 4-8 parts of vitamin K, 1 5-10 parts of vitamin B, 2 1-5 parts of vitamin B, 6 3-7 parts of vitamin B, 2-6 parts of nicotinic acid, 3-5 parts of pantothenic acid, 1-4 parts of vitamin B, 2-4 parts of vitamin C, 2-5 parts of folic acid, 1-3 parts of choline, 0.5-2 parts of L-carnitine, 2-4 parts of D-biotin, 3-5 parts of taurine and 0.5-2 parts of potassium iodide.
Further, the mineral compound consists of trace minerals and macro minerals according to the mass ratio of 0.1-0.2:6-8; trace minerals include copper sulfate, ferric pyrophosphate, manganese sulfate, sodium selenite, and zinc citrate; macro minerals include dibasic calcium phosphate, calcium carbonate, magnesium carbonate, potassium chloride, dibasic potassium phosphate and sodium citrate.
Further, the mass ratio of the copper sulfate, the ferric pyrophosphate, the manganese sulfate, the sodium selenite and the zinc citrate in the trace mineral is 3-5:3-5:2-4:1-3:1-3; the mass ratio of the calcium hydrophosphate, the calcium carbonate, the magnesium carbonate, the potassium chloride, the dipotassium hydrogen phosphate and the sodium citrate in the macro mineral is 8-12:5-10:4-6:2-4:2-4:1-3.
Further, the alcohol extraction in S1 comprises the following steps:
s1: drying the extract until the water content is lower than 15%; then spraying 8-12% saline and 75% ethanol solution to the surface of the extract at 25-35 ℃, wherein each spraying is performed for 3-5 times when the surface of the extract is wet and the liquid drops do not fall, and the spraying interval time of the saline and the ethanol is 10-20 min;
s2: placing the extract to be extracted after the S1 treatment in a vacuum tank, vacuumizing, controlling the temperature in the tank to be 65-75 ℃, carrying out vacuum treatment for 2-4 hours, taking out, and cooling to room temperature;
s3: mixing the extract to be extracted after the S2 treatment with an ethanol solution with the volume concentration of 85-90% according to the feed liquid ratio of 1:10-20 g/mL, soaking for 2-4 h, and pulping to obtain pulp to be extracted;
s4: ultrasonic extracting the slurry to be extracted at 25-35 deg.c, and filtering to obtain the extractive solution;
s5: concentrating the extractive solution under reduced pressure until no ethanol smell is present, to obtain ethanol extract.
The application also discloses a preparation method of the total nutrient special medical use formula food, which comprises the following steps:
s1: weighing the components according to the mass ratio relation;
s2: mixing the weighed components uniformly to obtain the final product.
The application also discloses application of the total nutrient special medical purpose formula food in preparing children nutritional supplements.
The beneficial effects of the application are as follows:
1. the total nutrient special medical use formula food disclosed by the application contains various components, can provide sufficient nutrient substances, can supplement nutrition required by a user, and is an aldehyde nutrition supplement with higher nutritional value.
2. The vegetable oil microcapsule powder is added into the formula food with special medical application, and contains extracts of Korean ginseng, dangshen and coix seed, and the three substances act together to regulate intestines and stomach and improve intestines and stomach functions, so that the intestines and stomach can promote the absorption of nutrient substances and the absorption and utilization rate of nutrient supplement reinforcing agents.
Drawings
FIG. 1 is the effect of example and comparative example formulations on mouse serum CPR levels;
FIG. 2 is the effect of example and comparative formulations on mouse serum immunoglobulin IgA levels;
FIG. 3 is the effect of the example and comparative formulas on mouse serum immunoglobulin IgG levels.
Detailed Description
The following describes the present application in detail with reference to examples.
Example 1
A formula food with full nutrition and special medical application comprises the following components in parts by mass:
60 parts of maltodextrin, 25 parts of corn syrup, 5 parts of fructo-oligosaccharide, 13 parts of galacto-oligosaccharide, 1 part of inulin, 60 parts of protein compound, 45 parts of vegetable oil microcapsule powder, 5 parts of DHA algae oil powder, 5 parts of arachidonic acid powder, 10 parts of fish oil microcapsule powder, 5 parts of vitamin compound and 10 parts of mineral compound.
The protein compound comprises the following components in parts by mass:
40 parts of whey protein, 15 parts of soy protein isolate, 25 parts of casein and 10 parts of milk protein isolate.
The vitamin compound comprises the following components in parts by mass:
10 parts of vitamin A, 4 parts of vitamin D, 3 parts of vitamin E, 5 parts of vitamin K, 16 parts of vitamin B, 2 4 parts of vitamin B, 6 4 parts of vitamin B, 4 parts of nicotinic acid, 4 parts of pantothenic acid, 12 parts of vitamin B, 3 parts of vitamin C, 3 parts of folic acid, 2 parts of choline, 1 part of L-carnitine, 3 parts of D-biotin, 4 parts of taurine and 1 part of potassium iodide.
The mineral compound consists of trace minerals and macro minerals according to the mass ratio of 0.2:8; the trace mineral is prepared by mixing copper sulfate, ferric pyrophosphate, manganese sulfate, sodium selenite and zinc citrate according to the mass ratio of 4:4:3:2:2; the macro mineral is prepared by mixing calcium hydrophosphate, calcium carbonate, magnesium carbonate, potassium chloride, dipotassium hydrogen phosphate and sodium citrate according to the mass ratio of 10:8:5:3:3:2.
The vegetable oil microcapsule powder is prepared through the following steps:
s1: respectively carrying out alcohol extraction on Korean ginseng, radix codonopsis pilosulae and coix seed, wherein the alcohol extraction comprises the following steps:
(1) Drying the extract until the water content is lower than 15%; then spraying 10% saline and 75% ethanol solution to the surface of the extract at 30deg.C, wherein each spraying is performed for 4 times when the surface of the extract is wet and the liquid drops do not fall, and the spraying interval time of the saline and ethanol is 15min;
(2) Placing the extract to be extracted treated in the step (1) in a vacuum tank, vacuumizing, controlling the temperature in the tank to be 70 ℃, and taking out and cooling to room temperature after vacuum treatment for 3 hours;
(3) Mixing the extract to be extracted treated in the step (2) with an ethanol solution with the volume concentration of 90% according to the feed liquid ratio of 1:15g/mL, soaking for 3 hours, and pulping to obtain pulp of the extract to be extracted;
(4) Ultrasonic extracting the slurry to be extracted at 30 ℃, and filtering to obtain an extracting solution to be extracted; the ultrasonic frequency is 40KHz during ultrasonic extraction, and the ultrasonic time is 90min;
(5) Concentrating the extractive solution under reduced pressure until no ethanol smell is present, to obtain ethanol extract.
S2: mixing alcoholic extracts of Korean ginseng, radix codonopsis pilosulae and coix seed according to the mass ratio of 4:2:1, and then co-dissolving the mixture, maltodextrin, sodium caseinate, sodium tripolyphosphate and sucrose fatty acid ester according to the mass ratio of 4:12:16:2:1:1 in water to obtain emulsion;
s3: adding emulsifier (Tween-20) into vegetable oil (oleum Lini), stirring at 120rpm at room temperature for 15min to obtain emulsified vegetable oil; the added emulsifying agent accounts for 0.5% of the mass of the vegetable oil;
s4: adding the emulsified vegetable oil into the emulsion under the stirring condition, and standing and emulsifying for 2h at 55 ℃ after the addition is finished;
s4: and (3) spray drying the feed liquid subjected to standing emulsification to obtain the vegetable oil microcapsule powder.
The formula food with full nutrition and special medical application in the embodiment is prepared through the following steps:
s1: weighing the components according to the mass ratio relation;
s2: mixing the weighed components uniformly to obtain the final product.
Example 2
A formula food with full nutrition and special medical application comprises the following components in parts by mass:
25 parts of maltodextrin, 50 parts of corn syrup, 1 part of fructo-oligosaccharide, 30 parts of galacto-oligosaccharide, 1 part of inulin, 100 parts of protein compound, 10 parts of vegetable oil microcapsule powder, 10 parts of DHA algae oil powder, 1 part of arachidonic acid powder, 20 parts of fish oil microcapsule powder, 0.5 part of vitamin compound and 20 parts of mineral compound.
The protein compound comprises the following components in parts by mass:
5 parts of whey protein, 25 parts of soy protein isolate, 3 parts of casein and 15 parts of milk protein isolate.
The vitamin compound comprises the following components in parts by mass:
5 parts of vitamin A, 6 parts of vitamin D, 2 parts of vitamin E, 8 parts of vitamin K, 15 parts of vitamin B, 25 parts of vitamin B6 3 parts of vitamin B, 6 parts of nicotinic acid, 3 parts of pantothenic acid, 12 parts of vitamin B, 2 parts of vitamin C, 5 parts of folic acid, 1 part of choline, 2 parts of L-carnitine, 2 parts of D-biotin, 5 parts of taurine and 0.5 part of potassium iodide.
The mineral compound consists of trace minerals and macro minerals according to the mass ratio of 0.1:6; the trace mineral is prepared by mixing copper sulfate, ferric pyrophosphate, manganese sulfate, sodium selenite and zinc citrate according to the mass ratio of 3:5:2:3:1; the macro mineral is prepared by mixing calcium hydrophosphate, calcium carbonate, magnesium carbonate, potassium chloride, dipotassium hydrogen phosphate and sodium citrate according to the mass ratio of 8:10:4:4:2:3.
The vegetable oil microcapsule powder is prepared through the following steps:
s1: respectively carrying out alcohol extraction on Korean ginseng, radix codonopsis pilosulae and coix seed, wherein the alcohol extraction comprises the following steps:
(1) Drying the extract until the water content is lower than 15%; then spraying saline with the mass concentration of 12% and ethanol solution with the volume concentration of 75% on the surface of the to-be-extracted at the temperature of 25 ℃, wherein each spraying is performed for 5 times when the surface of the to-be-extracted is wet and the liquid drops do not fall, and the spraying interval time of the saline and the ethanol is 10min;
(2) Placing the extract to be extracted treated in the step (1) in a vacuum tank, vacuumizing, controlling the temperature in the tank to be 65 ℃, and taking out and cooling to room temperature after vacuum treatment for 4 hours;
(3) Mixing the extract to be extracted treated in the step (2) with an ethanol solution with the volume concentration of 85% according to the feed liquid ratio of 1:20g/mL, soaking for 4 hours, and pulping to obtain pulp of the extract to be extracted;
(4) Ultrasonic extracting the slurry to be extracted at 25 ℃, and filtering to obtain an extracting solution to be extracted; the ultrasonic frequency is 40KHz during ultrasonic extraction, and the ultrasonic time is 90min;
(5) Concentrating the extractive solution under reduced pressure until no ethanol smell is present, to obtain ethanol extract.
S2: mixing alcoholic extracts of Korean ginseng, radix codonopsis pilosulae and coix seed according to the mass ratio of 2:3:1, and then co-dissolving the mixture, maltodextrin, sodium caseinate, sodium tripolyphosphate and sucrose fatty acid ester according to the mass ratio of 3:15:15:3:1:2 in water to obtain emulsion;
s3: adding emulsifier (Tween-20) into vegetable oil (soybean oil), and stirring at 150rpm at room temperature for 10min to obtain emulsified vegetable oil; the added emulsifying agent accounts for 1% of the mass of the vegetable oil;
s4: adding the emulsified vegetable oil into the emulsion under the stirring condition, and standing and emulsifying for 1h at 60 ℃ after the addition;
s4: and (3) spray drying the feed liquid subjected to standing emulsification to obtain the vegetable oil microcapsule powder.
The formula food with full nutrition and special medical application in the embodiment is prepared through the following steps:
s1: weighing the components according to the mass ratio relation;
s2: mixing the weighed components uniformly to obtain the final product.
Example 3
A formula food with full nutrition and special medical application comprises the following components in parts by mass:
100 parts of maltodextrin, 5 parts of corn syrup, 20 parts of fructo-oligosaccharide, 0.5 part of galacto-oligosaccharide, 5 parts of inulin, 20 parts of protein compound, 80 parts of vegetable oil microcapsule powder, 0.5 part of DHA algae oil powder, 10 parts of arachidonic acid powder, 1 part of fish oil microcapsule powder, 10 parts of vitamin compound and 1 part of mineral compound.
The protein compound comprises the following components in parts by mass:
80 parts of whey protein, 5 parts of soy protein isolate, 50 parts of casein and 5 parts of milk protein isolate.
The vitamin compound comprises the following components in parts by mass:
10 parts of vitamin A, 3 parts of vitamin D, 5 parts of vitamin E, 4 parts of vitamin K, 110 parts of vitamin B, 2 1 parts of vitamin B, 67 parts of vitamin B, 2 parts of nicotinic acid, 5 parts of pantothenic acid, 12 parts of vitamin B, 4 parts of vitamin C, 2 parts of folic acid, 3 parts of choline, 0.5 part of L-carnitine, 4 parts of D-biotin, 3 parts of taurine and 2 parts of potassium iodide.
The mineral compound consists of trace minerals and macro minerals according to the mass ratio of 0.2:6; the trace mineral is prepared by mixing copper sulfate, ferric pyrophosphate, manganese sulfate, sodium selenite and zinc citrate according to the mass ratio of 5:3:4:1:3; the macro mineral is prepared by mixing calcium hydrophosphate, calcium carbonate, magnesium carbonate, potassium chloride, dipotassium hydrogen phosphate and sodium citrate according to the mass ratio of 12:5:6:2:4:1.
The vegetable oil microcapsule powder is prepared through the following steps:
s1: respectively carrying out alcohol extraction on Korean ginseng, radix codonopsis pilosulae and coix seed, wherein the alcohol extraction comprises the following steps:
(1) Drying the extract until the water content is lower than 15%; then spraying 8% saline and 75% ethanol solution to the surface of the extract at 35 ℃ until the surface of the extract is wet and the liquid drops do not fall, wherein the spraying of the saline and the ethanol is carried out for 3 times, and the spraying interval time of the two solutions is 20min;
(2) Placing the extract to be extracted treated in the step (1) in a vacuum tank, vacuumizing, controlling the temperature in the tank to be 75 ℃, and taking out and cooling to room temperature after vacuum treatment for 2 hours;
(3) Mixing the extract to be extracted treated in the step (2) with an ethanol solution with the volume concentration of 85% according to the feed liquid ratio of 1:10g/mL, soaking for 2 hours, and pulping to obtain pulp of the extract to be extracted;
(4) Ultrasonic extracting the slurry to be extracted at 35 ℃, and filtering to obtain an extracting solution to be extracted; the ultrasonic frequency is 40KHz during ultrasonic extraction, and the ultrasonic time is 90min;
(5) Concentrating the extractive solution under reduced pressure until no ethanol smell is present, to obtain ethanol extract.
S2: mixing alcoholic extracts of Korean ginseng, radix codonopsis pilosulae and coix seed according to a mass ratio of 5:1:3, and then co-dissolving the mixture, maltodextrin, sodium caseinate, sodium tripolyphosphate and sucrose fatty acid ester according to a mass ratio of 5:10:20:1:2:0.5 in water to obtain emulsion;
s3: adding emulsifier (Tween-20) into vegetable oil (soybean oil), stirring at 120rpm at room temperature for 20min to obtain emulsified vegetable oil; the added emulsifying agent accounts for 0.5% of the mass of the vegetable oil;
s4: adding the emulsified vegetable oil into the emulsion under the stirring condition, and standing and emulsifying for 3 hours at 50 ℃ after the addition is finished;
s4: and (3) spray drying the feed liquid subjected to standing emulsification to obtain the vegetable oil microcapsule powder.
The formula food with full nutrition and special medical application in the embodiment is prepared through the following steps:
s1: weighing the components according to the mass ratio relation;
s2: mixing the weighed components uniformly to obtain the final product.
Comparative example 1
The procedure of example 1 was repeated except that the vegetable oil microcapsule powder of example 1 was replaced with linseed oil microcapsule powder (purchased from doctor biotechnology Co., miss.).
Comparative example 2
The vegetable oil microcapsule powder in example 1 was replaced with linseed oil, and the rest was the same as in example 1.
Comparative example 3
The vegetable oil microcapsule powder in example 1 was removed, and the rest was the same as in example 1.
Experimental example
1. Construction of gastrointestinal absorption dysfunction mouse model
A mouse animal model with dysfunction of gastrointestinal absorption was constructed according to the method described in patent 201410853675.0 to examine whether the nutrition in the nutrition supplement enhancer of the present application was sufficiently absorbed.
2. Mouse feeding
70 mice (listlessness, emaciation, matt and yellow hair and pale tail) were selected and evenly divided into 7 groups, numbered 1-7. The mice numbered 1 to 6 were fed with the nutrient supplement prepared in examples and comparative examples once at 10 am and 3 pm, respectively, and the mice numbered 7 were fed with maltodextrin, in addition to the normal feed per day. Mice were continuously fed for 30 days and observed for changes in hair color, tail of paw, and body weight.
3. Analysis of results
1. The feeding results of the mice are shown in table 1.
TABLE 1 mouse feeding status
As can be seen from Table 1, the mice were given sufficient nutritional supplements and had a large change in both mental state and physical state as the feed was fed with the nutritional supplement enhancer of the present application.
Comparative example 1 in comparison with example 1, the vegetable oil microcapsule powder was replaced with linseed oil microcapsule powder, and although the nutritional supplement also included various nutrients, it was possible to supplement the nutrition to mice, but these nutrients were not absorbed sufficiently for mice with weak gastrointestinal functions, and thus, the mental state and physical state of the mice were improved but not restored to normal state.
Also, the nutritional ingredients in the nutritional agents of comparative examples 2 and 3 were not sufficiently absorbed by the mice having weak gastrointestinal functions, and the mice were not restored to normal state although the mental state and physical state were improved.
The mice numbered 7 were not supplemented with nutrient substances and did not undergo a fundamental change in status.
2. Examination of the effects of the formulations of the examples and comparative examples on the immune response and resistance of mice
After the end of feeding, the inner canthus was bled to detect the serum C-reactive protein (CPR) and serum immunoglobulin IgA, igG levels, and the results are shown in fig. 1-3, wherein fig. 1 shows the effect of the nutritional supplement enhancer on the serum CPR level of mice, fig. 2 shows the effect of the nutritional supplement enhancer on the serum immunoglobulin IgA level of mice, fig. 3 shows the effect of the nutritional supplement enhancer on the IgG level of mice, P < 0.05 compared with the control group, and # shows P < 0.05 compared with the comparative example 3.
As can be seen from fig. 1, the nutritional supplement fortifier of examples 1-3 can significantly reduce CPR levels in mice and reduce inflammatory responses in mice. As can be seen from fig. 2 and 3, examples 1 to 3 can significantly increase serum immunoglobulin IgA and IgG levels, enhancing mouse resistance.
While specific embodiments of the application have been described in detail in connection with the examples, it should not be construed as limiting the scope of protection of the patent. Various modifications and variations which may be made by those skilled in the art without the creative effort are within the scope of the patent described in the claims.
Claims (10)
1. A formula food with full nutrition and special medical application is characterized by comprising maltodextrin, corn syrup, fructo-oligosaccharide, galacto-oligosaccharide, inulin, protein compound, vegetable oil microcapsule powder, DHA algae oil powder, arachidonic acid powder, fish oil microcapsule powder, vitamin compound and mineral compound;
the vegetable oil microcapsule powder is prepared through the following steps:
s1: respectively carrying out alcohol extraction on Korean ginseng, dangshen and coix seed, then mixing the alcohol extracts of the Korean ginseng, the dangshen and the coix seed according to the mass ratio of 2-5:1-3:1-3, and then co-dissolving the mixture with maltodextrin, sodium caseinate, sodium tripolyphosphate and sucrose fatty acid ester according to the mass ratio of 3-5:10-15:15-20:1-3:1-2:0.5-2 in water to obtain emulsion;
s2: adding an emulsifying agent into the vegetable oil, and stirring for 10-20 min at room temperature at a rotating speed of 100-150 rpm to obtain emulsified vegetable oil;
s3: adding the emulsified vegetable oil into the emulsion under the stirring condition, and standing and emulsifying for 1-3 h at 50-60 ℃ after the addition;
s4: and (3) spray drying the feed liquid subjected to standing emulsification to obtain the vegetable oil microcapsule powder.
2. The total nutrient special medical use formula of claim 1, comprising the following components in parts by mass:
25-100 parts of maltodextrin, 0-50 parts of corn syrup, 0-20 parts of fructo-oligosaccharide, 0-30 parts of galacto-oligosaccharide, 0-5 parts of inulin, 20-100 parts of protein compound, 10-80 parts of vegetable oil microcapsule powder, 0-10 parts of DHA algae oil powder, 0-10 parts of arachidonic acid powder, 0-20 parts of fish oil microcapsule powder, 0-10 parts of vitamin compound and 0-20 parts of mineral compound.
3. The total nutrient special medical use formula of claim 2, comprising the following components in parts by mass:
60 parts of maltodextrin, 25 parts of corn syrup, 5 parts of fructo-oligosaccharide, 13 parts of galacto-oligosaccharide, 1 part of inulin, 60 parts of protein compound, 45 parts of vegetable oil microcapsule powder, 5 parts of DHA algae oil powder, 5 parts of arachidonic acid powder, 10 parts of fish oil microcapsule powder, 5 parts of vitamin compound and 10 parts of mineral compound.
4. A total nutrient special medical use formula as claimed in any one of claims 1 to 3, wherein the protein complex comprises the following components in parts by mass:
5-80 parts of whey protein, 5-25 parts of soybean protein isolate, 3-50 parts of casein and 5-15 parts of milk protein isolate.
5. A total nutrient special medical use formula as claimed in any one of claims 1 to 3, wherein the vitamin complex comprises the following components in parts by mass:
5-10 parts of vitamin A, 3-6 parts of vitamin D, 2-5 parts of vitamin E, 4-8 parts of vitamin K, 1 5-10 parts of vitamin B, 2 1-5 parts of vitamin B, 6 3-7 parts of vitamin B, 2-6 parts of nicotinic acid, 3-5 parts of pantothenic acid, 1-4 parts of vitamin B, 2-4 parts of vitamin C, 2-5 parts of folic acid, 1-3 parts of choline, 0.5-2 parts of L-carnitine, 2-4 parts of D-biotin, 3-5 parts of taurine and 0.5-2 parts of potassium iodide.
6. A total nutrient special medical use formula as claimed in any one of claims 1 to 3, wherein the mineral complex consists of trace minerals and macro minerals in a mass ratio of 0.1 to 0.2:6 to 8; the trace minerals comprise copper sulfate, ferric pyrophosphate, manganese sulfate, sodium selenite and zinc citrate; the macro minerals include calcium hydrogen phosphate, calcium carbonate, magnesium carbonate, potassium chloride, dipotassium hydrogen phosphate and sodium citrate.
7. The total nutrient special medical use formula of claim 6, wherein: the mass ratio of the copper sulfate, the ferric pyrophosphate, the manganese sulfate, the sodium selenite and the zinc citrate in the trace mineral is 3-5:3-5:2-4:1-3:1-3; the mass ratio of the calcium hydrophosphate, the calcium carbonate, the magnesium carbonate, the potassium chloride, the dipotassium hydrogen phosphate and the sodium citrate in the macro mineral is 8-12:5-10:4-6:2-4:2-4:1-3.
8. The total nutrient special medical use formula of claim 1, wherein the alcohol extract in S1 comprises the steps of:
s1: drying the extract until the water content is lower than 15%; then spraying 8-12% saline and 75% ethanol solution to the surface of the extract at 25-35 ℃, wherein each spraying is performed for 3-5 times when the surface of the extract is wet and the liquid drops do not fall, and the spraying interval time of the saline and the ethanol is 10-20 min;
s2: placing the extract to be extracted after the S1 treatment in a vacuum tank, vacuumizing, controlling the temperature in the tank to be 65-75 ℃, carrying out vacuum treatment for 2-4 hours, taking out, and cooling to room temperature;
s3: mixing the extract to be extracted after the S2 treatment with an ethanol solution with the volume concentration of 85-90% according to the feed liquid ratio of 1:10-20 g/mL, soaking for 2-4 h, and pulping to obtain pulp to be extracted;
s4: ultrasonic extracting the slurry to be extracted at 25-35 deg.c, and filtering to obtain the extractive solution;
s5: concentrating the extractive solution under reduced pressure until no ethanol smell is present, to obtain ethanol extract.
9. A method of preparing a total nutrient special medical use formula as claimed in any one of claims 1 to 8 comprising the steps of:
s1: weighing the components according to the mass ratio relation;
s2: mixing the weighed components uniformly to obtain the final product.
10. Use of the total nutrient special medical use formula of any one of claims 1 to 8 in the preparation of a nutritional supplement for children.
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| CN202310421131.6A CN116636613A (en) | 2023-04-18 | 2023-04-18 | Formula food with full nutrition and special medical application as well as preparation method and application thereof |
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