CN1166352A - Wind dispelling and itching stopping medicine and its production - Google Patents
Wind dispelling and itching stopping medicine and its production Download PDFInfo
- Publication number
- CN1166352A CN1166352A CN 97105099 CN97105099A CN1166352A CN 1166352 A CN1166352 A CN 1166352A CN 97105099 CN97105099 CN 97105099 CN 97105099 A CN97105099 A CN 97105099A CN 1166352 A CN1166352 A CN 1166352A
- Authority
- CN
- China
- Prior art keywords
- grams
- gram
- radix
- herba schizonepetae
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The said medicine, granule or decoction, is prepared with 13 Chinese medicinal materials including Herba Schizonepetae, Radix Ledebouriellae, Radix Sophorae Flavescentis, Rhizoma Atractylodis, etc. It has the functions of dispelling wind, stopping itching, moistening dryness-syndrome and promoting the production of body fluid, and it is used for urticaria and pruritus caused by wind heat. Taking the medicine produces no narcolepsy and diziness, and animal experiment shows no side effect and resistance.
Description
The present invention is a kind of Chinese medicine, has the dermatosis of pruritus in order to treat acute and chronic urticaria, pruritus, eczema, neurodermatitis, drug eruption etc.
Urticaria, pruritus, eczema, neurodermatitis, drug eruption etc. are dermatology common disease, frequently-occurring disease, and pruritus is the common symptom of skin, and the patient suffering feels embarrassed to mention.The above-mentioned disease of treatment is mainly used the antihistaminic medicine both at home and abroad at present, as first generation antihistamine drug diphenhydramine, promethazine, chlorphenamine, Cyproheptadine etc.; Second filial generation antihistaminic cease this, teldane, loratadine, cetirizine, Mequitazine etc.The former has side effect such as drowsiness, dizzy, xerostomia, and work high above the ground, driver etc. can not be used, and latter's side effect is less, but costs an arm and a leg, and both prolonged application all have drug resistance.Differential diagnosis in tcm executes that to control prescription a lot, uses inconvenience but mostly be water decoction, and curative effect is also undesirable.
The objective of the invention is according to theory of Chinese medical science, develop and a kind ofly can take stopgap measures and can effect a permanent cure, curative effect height, toxic and side effects be little, take safety, pure Chinese medicinal preparation---dispelling wind for relieving itching medicament easily.
Content of the present invention is:
1, granule prescription:
Herba Schizonepetae 500-125 gram Radix Saposhnikoviae 125-500 gram
Radix Sophorae Flavescentis 500-125 gram Rhizoma Atractylodis 320-80 gram
Periostracum Cicadae 320-80 gram Gypsum Fibrosum 500-125 gram
Fructus Arctii 80-320 gram Caulis Aristolochiae Manshuriensis 80-320 gram
Radix Angelicae Sinensis 125-500 gram Rhizoma Anemarrhenae 80-320 gram
Radix Rehmanniae 125-500 KEHU Fructus Cannabis 80-320 gram
Radix Glycyrrhizae 80-320 gram
Adjuvant: sucrose 70 grams, starch 200 grams, dextrin 300 grams.
2, preparation granule technology:
Above 13 flavor medicines are according to dosage assorted, got wherein Herba Schizonepetae, Rhizoma Atractylodis, Radix Angelicae Sinensis, Radix Saposhnikoviae 4 flavors, extracted volatile oil 4 hours, distillate volatile oil is standby.Other gets and adds decocting after Gypsum Fibrosum is pulverized and decoct with water secondary with above-mentioned medicinal residues and all the other 8 flavor medicines after 1 hour, for the first time add 10 times of amounts of water, decocted 2 hours, add 8 times of amounts of water for the second time, decocted 2 hours, merge twice filtrate and above-mentioned distillate, filter, filtering is condensed into extractum, drying under reduced pressure, make dried cream, pulverize, cross 100 mesh sieves, again according to quantity with sucrose, starch, dextrin, mixing is used 70% alcohol granulation, and is dry, put cold, granulate, spray into volatile oil with dissolve with ethanol, mixing, airtight 2 hours, granulate, packing were promptly.
3, this medicament also can use decoct, and the principal agent prescription is: Herba Schizonepetae 500 grams, Radix Saposhnikoviae 500 grams, Radix Sophorae Flavescentis 500 grams, Rhizoma Atractylodis 500 grams, Periostracum Cicadae 500 grams, Fructus Arctii 500 grams, Caulis Aristolochiae Manshuriensis 500 grams, Radix Angelicae Sinensis 750 grams, the Rhizoma Anemarrhenae 500 grams, the Radix Rehmanniae 2500 grams, Gypsum Fibrosum 1250 grams, Semen Lini 750 grams, Radix Glycyrrhizae 500 grams.
Function of the present invention is: dispelling wind for relieving itching, and moisturize and promote the production of body fluid.Be used for the caused painful abdominal mass tumor of wind heat disease wind (acute urticaria), pruritus (pruritus) etc. has above-mentioned pruritus person.
The inventor has carried out abundant test to drug effect:
(1), by drug-induced animal skin pruritus effect test is shown that the dispelling wind for relieving itching medicament can obviously suppress medicine induced mice skin pruritus.
(2), show that by the anti-non-immunity contact urticaria of this medicine effect test this medicine has remarkable inhibitory action to the Cavia porcellus ear skin with the non-immunity contact urticaria that cinnamic acid and dimethyl sulfoxide brought out.
(3), by this medicine the influence of rat passive cutaneous anaphylaxis, PCA of the same race test is shown that this medicine can obviously suppress rat passive cutaneous anaphylaxis, PCA of the same race.
The influence test of rat cranial periosteum mast cell degranulation during (4), by this medicine, inquired into this medicine anti-allergic effects preliminary mechanism and with may the concerning of antiinflammatory, itching-relieving action, showing that this medical instrument has suppresses the effect of rat cranial periosteum mast cell granule significantly.
(5), by this medicine to the influence test of rat capillary permeability, inquire into its antiinflammatory action, test shows that this medical instrument has the effect that reduces the rat capillary permeability.
(6), the influence of dimethylbenzene induced mice ear swelling when this medicine, show that this medicine has that the struvite ear of obvious inhibitions mice is swollen to be acted on.
(7), according to Beijing Gate of Pervasive Peace hospital, Traditional Chinese Medicinal College of Liaoning, Liaoning Province hospital, the four tame large hospital clinical observations of Shenyang City central hospital, the dispelling wind for relieving itching total effective rate is about 85%, cure rate about 60%.
Every test proves that fully advantage of the present invention is: take the back no drowsiness, do not have dizzy phenomenon, almost non-toxic side effect, and take stable curative effect for a long time has no drug resistance, and is particularly easy to carry, is convenient to take.
Embodiments of the invention are as follows:
Embodiment 1
Herba Schizonepetae 500 grams, Radix Saposhnikoviae 500 grams, Radix Sophorae Flavescentis 500 grams, Periostracum Cicadae 320 grams, Rhizoma Atractylodis 320 grams, Gypsum Fibrosum 500 grams, Fructus Arctii 80 grams, Caulis Aristolochiae Manshuriensis 80 grams, Radix Angelicae Sinensis 125 grams, the Rhizoma Anemarrhenae 80 grams, Radix Rehmanniae 125 grams, Semen Lini 80 grams, Radix Glycyrrhizae 80 grams.
Embodiment 2
Herba Schizonepetae 125 grams, Radix Saposhnikoviae 125 grams, Radix Sophorae Flavescentis 125 grams, Periostracum Cicadae 80 grams, Rhizoma Atractylodis 80 grams, Gypsum Fibrosum 125 grams, Fructus Arctii 320 grams, Caulis Aristolochiae Manshuriensis 320 grams, Radix Angelicae Sinensis 500 grams, the Rhizoma Anemarrhenae 320 grams, Radix Rehmanniae 500 grams, Semen Lini 320 grams, Radix Glycyrrhizae 320 grams.
Embodiment 3
Herba Schizonepetae 250 grams, Radix Saposhnikoviae 250 grams, Radix Sophorae Flavescentis 250 grams, Periostracum Cicadae 160 grams, Rhizoma Atractylodis 160 grams, Fructus Arctii 160 grams, Caulis Aristolochiae Manshuriensis 160 grams, Radix Angelicae Sinensis 250 grams, the Rhizoma Anemarrhenae 160 grams, Radix Rehmanniae 250 grams, Gypsum Fibrosum 250 grams, Semen Lini 160 grams, Radix Glycyrrhizae 160 grams.
Herba Schizonepetae in above 3 examples, Rhizoma Atractylodis, Radix Angelicae Sinensis, Radix Saposhnikoviae were extracted volatile oil 4 hours, medicinal residues and distillate, volatile oil is standby.Other gets the Gypsum Fibrosum pulverizing and adds decocting after 1 hour, adds all the other medicines and above-mentioned medicinal residues by above-mentioned dosage again, adds the decocting in water secondary, merging filtrate and distillate, being concentrated into density is (60-70 ℃) extractum of 1.33-1.35, in 60-80 ℃ of drying under reduced pressure, make dried cream, pulverize, cross 100 mesh sieves, with sucrose 70 gram, starch 200 grams, dextrin 300 gram mixings, use 70% alcohol granulation again, drying, put cold, granulate, spray into volatile oil with dissolve with ethanol, mixing, airtight 2 hours, the granulate packing.Make 1000 grams for every dose, one time 10 gram of usage, three times on the one, for oral administration.
Embodiment 4
Herba Schizonepetae 500 gram, Radix Saposhnikoviae 500 grams, Radix Sophorae Flavescentis 500 grams, Periostracum Cicadae 500 grams, Fructus Arctii 500 grams, close logical 500 grams of art, Radix Angelicae Sinensis 750 grams, the Rhizoma Anemarrhenae 500 grams, Radix Rehmanniae 2500 grams, Gypsum Fibrosum 1250 grams, Semen Lini 750 grams, Radix Glycyrrhizae 500 grams.
Add water and surpass 3 centimetres of powder, the little fire in boiled back keeps boiling and boils state half an hour, and the first pass medicinal liquid is poured out, and adds water again and surpasses 2 centimetres of powder, and the little fire in boiled back keeps boiling and boils state half an hour, medicinal liquid is poured out again, and twice decoct adds about together 12500 milliliters.
Usage: each 50 milliliters, twice of every day is for oral administration.
Claims (5)
1, dispelling wind for relieving itching medicament is characterized in that its prescription has: Herba Schizonepetae 500-125 gram, Radix Saposhnikoviae 125-500 gram, Radix Sophorae Flavescentis 500-125 gram, Rhizoma Atractylodis 320-80 gram, Periostracum Cicadae 320-80 gram, Gypsum Fibrosum 500-125 gram, Fructus Arctii 80-320 gram, Caulis Aristolochiae Manshuriensis 80-320 gram, Radix Angelicae Sinensis 125-500 gram, Rhizoma Anemarrhenae 80-320 gram, Radix Rehmanniae 125-500 KEHU Fructus Cannabis 80-320 gram, Radix Glycyrrhizae 80-320 gram; And granulation adjuvant.
2, the manufacture method of dispelling wind for relieving itching pharmacy particle agent is characterized in that; According to dosage get Herba Schizonepetae, Rhizoma Atractylodis, Radix Angelicae Sinensis, Radix Saposhnikoviae four Chinese medicine, extracted volatile oil 4 hours, it is standby to get distillate and volatile oil; After getting and decoct with water 1 hour after Gypsum Fibrosum is pulverized, other decocts with water secondary with above-mentioned medicinal residues and all the other 8 flavor medicines, add for the first time 10 times of amounts of water, add for the second time 8 times of amounts of water, respectively boiled 2 hours, and merged twice filtrate and above-mentioned distillate, refilter, be condensed into extractum, drying under reduced pressure is made dried cream, pulverizes, sieves; Then with sucrose, starch, dextrin, mixing with 70% alcohol granulation, drying, put cold, granulate, sprays into the volatile oil with dissolve with ethanol, mixing, and airtight 2 hours, the granulate packing.
3, medicament according to claim 1 is characterized in that best granule prescription is: Herba Schizonepetae 250 grams, Radix Saposhnikoviae 250 grams, Radix Sophorae Flavescentis 250 grams, Rhizoma Atractylodis 160 grams, Periostracum Cicadae 160 grams, Caulis Aristolochiae Manshuriensis 160 grams, Radix Angelicae Sinensis 250 grams, the Rhizoma Anemarrhenae 160 grams, Fructus Arctii 160 grams, Radix Rehmanniae 250 grams, Gypsum Fibrosum 250 grams, Semen Lini 160 grams, Radix Glycyrrhizae 160 grams; Other adds adjuvant sucrose 70 grams, starch 200 grams, dextrin 300 grams, makes 1000 grams.
4, medicament according to claim 1 is characterized in that best decoct prescription is; Herba Schizonepetae 500 grams, Radix Saposhnikoviae 500 grams, Radix Sophorae Flavescentis 500 grams, Periostracum Cicadae 500 grams, Fructus Arctii 500 grams, Caulis Aristolochiae Manshuriensis 500 grams, Radix Angelicae Sinensis 750 grams, the Rhizoma Anemarrhenae 500 gram Radix Rehmanniae 2500 gram Gypsum Fibrosum 1250 grams, Semen Lini 750 grams, Radix Glycyrrhizae 500 grams.
5, medicament according to claim 1, the processing technology that it is characterized in that decoct is: add water and surpass 3 centimetres of powder, the little fire in boiled back keeps fluidized state half an hour, the first pass medicinal liquid is poured out, add water again and surpass 2 centimetres of powder, the little fire in boiled back keeps fluidized state half lobule, second time medicinal liquid is poured out again, and twice decoct adds standby together.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97105099 CN1166352A (en) | 1997-02-19 | 1997-02-19 | Wind dispelling and itching stopping medicine and its production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97105099 CN1166352A (en) | 1997-02-19 | 1997-02-19 | Wind dispelling and itching stopping medicine and its production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1166352A true CN1166352A (en) | 1997-12-03 |
Family
ID=5167658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 97105099 Pending CN1166352A (en) | 1997-02-19 | 1997-02-19 | Wind dispelling and itching stopping medicine and its production |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1166352A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1321669C (en) * | 2004-10-14 | 2007-06-20 | 李爱英 | Chinese herbal medicine for treating urticaria |
| CN101077386B (en) * | 2007-05-25 | 2010-07-21 | 赵善菊 | Traditional Chinese medicine composition for treating allergic purpura |
| CN101032611B (en) * | 2006-03-09 | 2012-03-21 | 辽宁康辰药业有限公司 | Antipruritic composite Chinese medicine and its preparing process |
| CN101214345B (en) * | 2007-12-26 | 2012-04-18 | 长春同春堂皮肤病医院 | Chinese medicine preparation for treating various itching skin diseases such as eczema dermatitis, urticaria and etc. |
| CN102813799A (en) * | 2012-08-18 | 2012-12-12 | 王济见 | Medicament for treating intractable skin disease |
| CN104042866A (en) * | 2013-03-16 | 2014-09-17 | 金万禄 | Vitligo treatment medicine |
-
1997
- 1997-02-19 CN CN 97105099 patent/CN1166352A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1321669C (en) * | 2004-10-14 | 2007-06-20 | 李爱英 | Chinese herbal medicine for treating urticaria |
| CN101032611B (en) * | 2006-03-09 | 2012-03-21 | 辽宁康辰药业有限公司 | Antipruritic composite Chinese medicine and its preparing process |
| CN101077386B (en) * | 2007-05-25 | 2010-07-21 | 赵善菊 | Traditional Chinese medicine composition for treating allergic purpura |
| CN101214345B (en) * | 2007-12-26 | 2012-04-18 | 长春同春堂皮肤病医院 | Chinese medicine preparation for treating various itching skin diseases such as eczema dermatitis, urticaria and etc. |
| CN102813799A (en) * | 2012-08-18 | 2012-12-12 | 王济见 | Medicament for treating intractable skin disease |
| CN104042866A (en) * | 2013-03-16 | 2014-09-17 | 金万禄 | Vitligo treatment medicine |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101987123B (en) | Medicament for easing pain of human body and preparation method thereof | |
| CN101195008B (en) | Cattail pollen skin cleaning agent for treating gynecology disease and technique of preparing the same thereof | |
| CN101632737A (en) | Medicament for relieving pain of human body and preparation method thereof | |
| CN1840117A (en) | Dermatosis-treating medicine | |
| CN101987122A (en) | Medicament for easing pain of human body and preparation method thereof | |
| CN1107057A (en) | Children coryza medicine and preparing method | |
| CN104491052B (en) | Traditional Chinese medicine composition for treating rheumatic and rheumatoid arthritis and preparation method thereof | |
| CN1739611A (en) | Stasis relieving oral liquid for treating rhinitis and its prepn | |
| CN1966052A (en) | Tablet containing red sage root and astragalus root for removing blood stasis and preparation process thereof | |
| CN1166352A (en) | Wind dispelling and itching stopping medicine and its production | |
| CN1985921B (en) | Chinese medicine composition for treating common cold and its preparing method | |
| CN101658585B (en) | Application of Chinese medicinal composition in preparing medicament for treating nasosinusitis | |
| CN1166388C (en) | Medicine for treating nosal inflammation | |
| CN101045152A (en) | Traditional Chinese medicine composition for treating chronic pelvic inflammatory disease concomitant inflammatory swelling | |
| CN1191847C (en) | Medicated pillow and its making process | |
| CN102940757B (en) | Medicine composition for treating diabetic foot | |
| CN1255170C (en) | Cough-relieving bagged tea and its prepn | |
| CN1814195A (en) | Chinese medicine composition for treating gynecopathy and use thereof | |
| CN1325096C (en) | Chinese medicine formulation for treating ance disease | |
| CN102488774B (en) | Chinese medicinal powder for treating canker sore and preparation method thereof | |
| CN1631388A (en) | Chinese traditional medicine for treating chronic prostatitis | |
| CN1669571A (en) | Chinese traditional medicine for treating enteritis and appendicitis, and method for preparing same | |
| CN100337659C (en) | Chinese medicine composition for treating acne and its preparing method | |
| CN1306830A (en) | Medicine for treating Type-11 diabetes | |
| CN101879227B (en) | Chinese medicinal composition for treating protrusion of lumbar intervertebral disci and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |