CN116585519A - Peach leaf plant extract relieving and repairing essence disposable hygienic product nursing base material, preparation method and application - Google Patents

Peach leaf plant extract relieving and repairing essence disposable hygienic product nursing base material, preparation method and application Download PDF

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Publication number
CN116585519A
CN116585519A CN202310302791.2A CN202310302791A CN116585519A CN 116585519 A CN116585519 A CN 116585519A CN 202310302791 A CN202310302791 A CN 202310302791A CN 116585519 A CN116585519 A CN 116585519A
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parts
skin
efficacy
substrate according
microemulsion
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许旭芳
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Kingdom Healthcare Holdings Ltd Guangdong
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Kingdom Healthcare Holdings Ltd Guangdong
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention discloses a nursing substrate of disposable hygienic products of peach leaf plant extraction relieving and repairing essence, a preparation method and application, wherein the essence is prepared from the following raw materials: the peach leaf extract, the microemulsion efficacy emulsifying agent, the oat kernel oil, the thickening agent, the humectant, the accelerator, the anti-allergic agent, the solubilizer and the non-irritating preservative composition are mutually cooperated, and the prepared sanitary towel (a protection pad and female sanitary trousers) can obviously reduce the irritation, pain and itching discomfort of female pudendum, relieve the symptoms of pudendum inflammation, itching, stinging and the like, and the microemulsion efficacy emulsifying agent has small particle size and is easy to absorb, can better permeate the effective components into skin, moisten and nourish the vulva skin and keep the vitality of the efficacy components; the biological sugar gum-1 has strong water binding capacity, good water absorption effect even in low humidity environment, and forms a breathable sugar film on the surface layer of the skin to prevent the skin moisture from evaporating again, and endows the product with soft silky skin feel, and the prepared sanitary towel (protective pad and female sanitary trousers) is soft and comfortable.

Description

Peach leaf plant extract relieving and repairing essence disposable hygienic product nursing base material, preparation method and application
Technical Field
The invention relates to a disposable hygienic product nursing base material, in particular to a peach leaf plant extract relieving and repairing essence disposable hygienic product nursing base material, a preparation method and application.
Background
Sanitary napkins, pads and feminine hygiene pants are close to the vulva skin, the vulva of a woman can feel red, swelling, pain and itching, discomfort and the like due to the fact that the vulva is in a moist and stuffy environment for a long time, chemical substances are easy to stimulate for a long time to cause allergy, and when the number of bacteria is too large, inflammation is easy to induce to generate discomfort, and the problems seriously affect the life quality of the woman.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention provides a nursing substrate for disposable hygienic products of peach leaf plant extraction relieving and repairing essence, a preparation method and application.
The technical scheme adopted for solving the technical problems is as follows:
a nursing base material of disposable hygienic products of peach leaf plant extract soothing and repairing essence is prepared from the following raw materials in parts by weight: 6.0 to 10.0 parts of peach leaf extract, 2.0 to 5.0 parts of microemulsion efficacy emulsifying agent, 5.0 to 10.0 parts of oat kernel oil, 0.05 to 0.2 parts of thickening agent, 5.0 to 10.0 parts of humectant, 0.1 to 1.0 part of accelerator, 0.1 to 1.0 part of sensitizer, 1.0 to 5.0 parts of solubilizer, 0.5 to 1.0 part of non-irritating preservative composition and 55 to 80 parts of pure water.
The microemulsion efficacy emulsifier is prepared from the following raw materials in parts by weight: 10-15 parts of butanediol (CAS: 107-88-0), 10-15 parts of hydrogenated castor oil, 1-3 parts of hydrogenated polyisobutene (CAS: 61693-08-1), 1-3 parts of cetostearyl isononanoate (CAS: 84878-1), 1-3 parts of cetostearyl alcohol polyether (CAS: 68439-49-6), 1-3 parts of cetostearyl alcohol (CAS: 67762-27-0), 1-3 parts of glycerol stearate (CAS: 123-94-4), 1-3 parts of cetyl alcohol palmitate (CAS: 540-10-3), 15-20 parts of sodium lysinate, 1-3 parts of phenoxyethanol and 60-70 parts of pure water.
The thickener is a mixture of cetostearyl glucoside (CAS: 246159-33-1) and cetostearyl alcohol (chemical formula: C34H72O 2) in any proportion.
The non-irritating antiseptic composition is glycerol octanoate and octanoyl hydroxamic acid (formula C 8 H 17 NO 2 ) P-hydroxyacetophenone (formula C) 8 H 8 O 2 ) And butanediol (chemical formula C) 4 H 10 O 2 ) The adopted raw materials are all mild raw materials, the skin is not stimulated, and the non-stimulated preservative composition can endow the invention with excellent preservative performance and prolong the storage time of the product.
The antiallergic agent is herba Centellae extract and cyclodextrin (molecular formula C) 42 H 70 O 35 ) The mixture with any proportion can effectively relieve the irritation, pain and itching discomfort of female pudendum and relieve the symptoms of pudendum inflammation, pudendum itching, stinging and the like.
The solubilizer is polysorbate-80 (chemical formula is C 64 H 124 O 26 ) Polysorbate-80 is an excellent O/W type emulsifier, and the high concentration electrolyte and the change of pH value have little influence on the emulsifying capacity. Has good emulsifying effect on vegetable oil, mineral oil, animal fat and the like, and has good solubilization effect on nonpolar compounds and compounds containing polar groups.
The humectant is butanediol (chemical formula C 4 H 10 O 2 ) Butanediol is a hydrophilic emollient substance with the ability to bind water in a lower humidity range and to replenish the skin with water, and they can maintain the skin at an equilibrium state higher than normal water content by controlling the exchange of water between the product and the surrounding air, thus acting to alleviate skin dryness.
The peach leaf is leaf of peach of Rosaceae, contains chemical components such as ursolic acid, hesperetin, etc., has effects of sterilizing, resisting virus, resisting oxidation, resisting cancer, fading color spots, balancing skin grease, softening cutin, etc., and has effects of relieving stomach ache and diarrhea, and can be used for treating heat rash, eczema, edema and skin rash caused by diaper, etc. The peach leaf extraction method is a conventional method and is known, and the peach leaf extract mainly contains Alkaloid (alloid), flavonol (Flavonol), chlorophyll (chlorophyl), pectin (pectin), amino acid and the like, and particularly, the peach leaf extract is rich in beta-glucan, can stimulate cells to express Heat Shock Proteins (HSPs), antioxidant proteins and longevity proteins, and is beneficial to stimulating the self-protection and repair of the cells, helping the skin resist external injury, maintaining skin moisture, removing free radicals, imparting skin softness and delaying aging.
Oat originates from the fourth largest and third largest oat producing countries in the world, and is one of the north most oat growths, the raw material of oat is produced with higher quality from the arctic cold region, is precipitated in winter, is inoculated in sunny summer, and has precious bioactive compounds. Oat kernel oil is extracted from oat kernel, has beneficial characteristics of oat, and is rich in essential fatty acid and phenolic compounds. The oat kernel oil has natural softening, moisturizing and moistening components, is very suitable for skin care and care of sensitive muscles, can quickly repair skin barriers, and can resist sensitization injury.
In particular, OMEGA-6 fatty acids, an active ingredient in oat kernel oil, reduce transepidermal water loss and repair skin barrier function, and linoleic acid maintains acid layers in the stratum corneum, forming the natural antimicrobial defense mechanism of the skin. The active ingredient ceramide in the oat kernel oil is the same lipid as the skin membrane, and protects the skin from external injury. The tocopherol in the oat kernel oil is a part of the natural defense system, and the tocopherol is a main fat-soluble natural antioxidant in the stratum corneum, so that the moisture content of skin can be increased, the roughness of the skin can be improved, and the irritation can be relieved.
The accelerator of the invention is biological polysaccharide gum, and FUCOGEL biological polysaccharide gum-1 is selected. The biological polysaccharide gum-1 is a 1% linear polysaccharide viscous solution obtained by bacterial fermentation of plant materials by biological processes. Because it has good sensory advantage and moisturizing effect, it is a good "active excipient". The excellent film-forming properties of the biopolysaccharide gum-1 are due to its high molecular weight polysaccharide content, while the "water absorbing" ability of the saccharide enhances its moisturizing efficacy. Since the molecular weight of the biopolysaccharide gum-1 is smaller than that of hyaluronic acid, its immediate hydration after 1 hour is slightly inferior to that of hyaluronic acid, but the biopolysaccharide gum-1 can provide stronger hydration to the skin from a long time, because it is more easily degraded into smaller molecular sugars by skin enzymes to naturally capture water molecules.
Biopolysaccharide gum-1 promotes removal of blunt macrophages from the infected site by competitively inhibiting m.i.f (macrophage migration inhibitory factor). M.i.f can immobilize itself on the receptor of macrophages or on the fucose contained in the biopolysaccharide gum-1, and when immobilized on the fucose, macrophages are not activated by m.i.f and remain in an inert state, so as to be removed from the affected site, accelerating the repair of the sebum barrier by 40% and reducing the percutaneous moisture loss.
In the microemulsion efficacy emulsifier, cetostearyl alcohol isononanoate is used as a softening agent, so that the skin softness can be improved, the skin is fine and smooth, cetostearyl alcohol polyether-20 is used as a cleaning agent, an emulsifying agent and a surfactant, cetostearyl alcohol is a nonionic emulsifying agent, a water-based formula can be thickened, a certain moisturizing effect is achieved, and cetylpalmitate can play roles in skin care, whitening and moisturizing.
A method for preparing the care substrate, comprising the following steps:
(1) Preparation of component A: adding the peach leaf extract, the microemulsion efficacy emulsifier and the oat kernel oil in parts by weight into a stirrer A, and then mixing for 5-10 minutes at the rotating speed of 50-60 rpm to obtain a component A.
(2) Preparation of component B: adding the humectant, the accelerator, the anti-allergic agent, the solubilizer and the non-irritating preservative composition in parts by weight into a stirrer B, and then mixing for 5-10 minutes at the rotating speed of 50-60 rpm to obtain the component B.
(3) Mixing and discharging: adding the pure water in parts by weight into a main stirring kettle, adding the component A into the main stirring kettle, keeping the rotating speed at 50-60 rpm for stirring for 15-25 minutes, heating the main stirring kettle to 45 ℃ while stirring, adding the component B into the main stirring kettle at 45 ℃ at the rotating speed at 50-60 rpm for stirring for 5-10 minutes, adding the thickener in parts by weight into the main stirring kettle, keeping the rotating speed at 50-60 rpm, stirring for 15-25 minutes, standing, and discharging.
A sanitary towel (pad, female sanitary pants) using the nursing substrate has the following preparation process: spraying the nursing base material of the peach She Zhicui relief repair essence disposable sanitary article on the non-woven fabric on the surface layer (a protection pad and female sanitary trousers) of the sanitary towel, extruding the non-woven fabric by rollers, drying at 80-85 ℃, and drying to obtain the peach She Zhicui relief repair essence sanitary towel (the protection pad and the female sanitary trousers).
The beneficial effects of the invention are as follows: the sanitary towel (pad and female sanitary trousers) is added with peach leaf extraction, microemulsion efficacy emulsifying agent, oat kernel, thickening agent, humectant, accelerator, anti-allergic agent, solubilizer and non-irritating antiseptic composition, and the components are mutually cooperated, so that the prepared sanitary towel (pad and female sanitary trousers) can obviously reduce the irritation and pain and itching discomfort of female pudendum and relieve the symptoms of pudendum inflammation, pudendum itch, stinging and the like.
The preparation method comprises the steps of preparing the components A and B and mixing and discharging, wherein the microemulsion efficacy emulsifier has small particle size and is easy to absorb, so that the effective components can better permeate into skin, the skin can be moistened and nourished, and the activity of the efficacy components is maintained; in addition, the biological sugar gum-1 has strong water binding capacity, good water absorption effect even in low humidity environment, and simultaneously forms a breathable sugar film on the surface layer of the skin to prevent the skin moisture from evaporating again, and the biological sugar gum-1 has instant and long-acting moisturizing effect, endows the product with soft silky skin feel, brings silky texture to the skin, and prevents the prepared sanitary towel (protective pad and female sanitary trousers) from getting silky, soft and comfortable.
Description of the embodiments
In all the embodiments of the present invention, the temperature and the pressure are not particularly emphasized, and are normal temperature and normal pressure, and the use of the device is not particularly described, and the device can be used according to the conventional arrangement.
Examples
Nursing substrate components: peach leaf extract (manufacturer: ICHIMARU PHARCOS Co., ltd., product name: peach Leaf Liquid B, peach (PRUNUS PERICA) leaf extract, the same as in the following examples) 6.0 parts, microemulsion efficacy emulsifier 2.0 parts, oat kernel oil (origin: finland, product name: jidihuang golden oat oil, the same as in the following examples) 5.0 parts, cetostearyl glucoside (thickener) 0.01 parts, cetostearyl alcohol (thickener) 0.04 parts; 5.0 parts of butanediol (humectant); biological gum-1 (accelerator, france mantel biological gum, trade name: fuprogel biological gum-1, same examples below), centella asiatica extract (sensitizer, centella asiatica extract from Shanyuan Biotech Co., ltd., same examples below) 0.1 parts, cyclodextrin (sensitizer, molecular formula C42H70O 35) 0.05 parts, polysorbate-80 (solubilizer, formula C64H124O 26) 1.0 parts, glyceryl caprylate (non-irritating preservative composition) 0.125 parts, octanoic acid (non-irritating preservative composition) 0.125 parts, p-hydroxyacetophenone (non-irritating preservative composition) 0.125 parts, butylene glycol (non-irritating preservative composition) 0.125 parts, pure water 55.
Microemulsion efficacy emulsifier component: 10 parts of butanediol (CAS: 107-88-0), 10 parts of hydrogenated castor oil (preferably PEG-60 hydrogenated castor oil manufactured by Hubei Tosoh chemical Co., ltd., the same applies to the examples below), 10 parts of hydrogenated polyisobutene (CAS: 61693-08-1, preferably manufactured by Hubei Xin Rundex chemical Co., ltd., the same applies to the examples below), 1 part of cetostearyl alcohol isononanoate (CAS: 84878-33-1), 1 part of cetostearyl alcohol polyether-20 (CAS: 68439-49-6), 1 part of cetostearyl alcohol (CAS: 67762-27-0), 1 part of glyceryl stearate (CAS: 123-94-4), 1 part of cetyl palmitate (CAS: 540-10-3), 15 parts of sodium lysinate (also known as sodium lysinate, manufactured by Guangshi trade Co., ltd.), 1 part of phenoxyethanol and 60 parts of pure water.
The preparation process of the microemulsion efficacy emulsifier comprises the following steps: preheating a reaction kettle, heating the reaction kettle to 50-60 ℃ (in the range, without strict requirements), adding the hydrogenated castor oil, hydrogenated polyisobutene, cetostearyl alcohol isononanoate, cetostearyl alcohol polyether-20, cetostearyl alcohol, glyceryl stearate and cetyl alcohol palmitate in parts by weight, stirring for 15-20min (in the range, without strict requirements), and stirring at a speed of 60-65r/min (in the range, without strict requirements), so as to obtain an oil phase; pouring the butanediol, the sodium lysinate and the pure water in parts by weight after stirring, continuing to react for 20-25min (all without strict requirements in the range), keeping the stirring speed of 60-65r/min (all without strict requirements in the range) and the reaction temperature of 50-60 ℃ (all without strict requirements in the range), cooling to room temperature, and standing to obtain the microemulsion efficacy emulsifier.
A method for preparing the care substrate, comprising the following steps:
(1) Preparation of component A: the peach leaf extract, the microemulsion efficacy emulsifying agent and the oat kernel oil in parts by weight are added into a stirrer A, and then mixed for 5-10 minutes (all can be in the range without strict requirements) at the rotating speed of 50-60 revolutions per minute (all can be in the range without strict requirements), so that the component A is prepared.
(2) Preparation of component B: the humectant, the accelerator, the anti-allergic agent, the solubilizer and the non-irritating preservative composition in parts by weight are added into a stirrer B, and then mixed for 5-10 minutes (all can be in the range without strict requirements) at the rotating speed of 50-60 revolutions per minute (all can be in the range without strict requirements), so that the component B is prepared.
(3) Mixing and discharging: adding the pure water in the weight parts into a main stirring kettle, adding the component A into the main stirring kettle, keeping the rotating speed at 50-60 revolutions per minute (all without strict requirements in the range), stirring for 15-25 minutes (all without strict requirements in the range), heating the main stirring kettle to 45 ℃ while stirring, adding the component B into the main stirring kettle at 45 ℃, keeping the rotating speed at 50-60 revolutions per minute (all without strict requirements in the range), stirring for 5-10 minutes, adding the thickener in the weight parts into the main stirring kettle, keeping the rotating speed at 50-60 revolutions per minute (all without strict requirements in the range), stirring for 15-25 minutes (all without strict requirements in the range), standing, and discharging.
A sanitary towel (pad, female sanitary pants) using the nursing substrate has the following preparation process: spraying the peach She Zhicui relief repair essence disposable sanitary article nursing base material on non-woven fabrics on the surface layer of a sanitary towel (a protective pad and female sanitary trousers), then carrying out roller extrusion on the non-woven fabrics, and then drying at 80-85 ℃ (within the range, the temperature is not strictly required), thus obtaining the peach She Zhicui relief repair essence sanitary towel (the protective pad and the female sanitary trousers).
In the following examples, the process for preparing the microemulsion efficacy emulsifier, the process for preparing the nursing base material, and the process for preparing the sanitary towel (pad, feminine hygiene pants) are the same as in example 1, except that the components are different.
Examples
Nursing substrate components: 7.0 parts of peach leaf extract, 3.0 parts of microemulsion efficacy emulsifier, 5.0 parts of oat kernel oil, 0.05 part of cetostearyl glucoside and 0.05 part of cetostearyl alcohol; 6.0 parts of butanediol; 0.3 part of biological sugar gum, 0.1 part of centella asiatica extract, 0.1 part of cyclodextrin, 2.0 parts of polysorbate-80, 0.15 part of glyceryl caprylate, 0.15 part of octanoyl hydroxamic acid, 0.15 part of p-hydroxyacetophenone, 0.15 part of butanediol and 65 parts of pure water.
Microemulsion efficacy emulsifier component: 12 parts of butanediol, 10 parts of hydrogenated castor oil, 2 parts of hydrogenated polyisobutene, 2 parts of cetostearyl alcohol isononanoate, 20 parts of cetostearyl alcohol polyether, 1 part of cetostearyl alcohol, 2 parts of glycerol stearate, 1 part of cetylpalmitate, 15 parts of sodium lysinate, 1 part of phenoxyethanol and 65 parts of pure water.
Examples
Nursing substrate components: 8.0 parts of peach leaf extract, 3.0 parts of microemulsion efficacy emulsifier, 6.0 parts of oat kernel oil, 0.05 part of cetostearyl glucoside and 0.10 part of cetostearyl alcohol; 7.0 parts of butanediol; 0.5 part of biological sugar gum-1, 0.2 part of centella asiatica extract, 0.3 part of cyclodextrin, 3.0 parts of polysorbate-80, 0.175 part of glyceryl caprylate, 0.175 part of octanoyl hydroxamic acid, 0.175 part of p-hydroxyacetophenone, 0.175 part of butanediol and 75 parts of pure water.
Microemulsion efficacy emulsifier component: 13 parts of butanediol, 12 parts of hydrogenated castor oil, 1.5 parts of hydrogenated polyisobutene, 1 part of cetostearyl alcohol isononanoate, 20 parts of cetostearyl alcohol polyether, 2 parts of cetostearyl alcohol, 2 parts of glycerol stearate, 2 parts of cetyl palmitate, 18 parts of sodium lysinate, 2 parts of phenoxyethanol and 65 parts of pure water.
Examples
Nursing substrate components: 9.0 parts of peach leaf extract, 4.0 parts of microemulsion efficacy emulsifier, 8.0 parts of oat kernel oil, 0.10 part of cetostearyl glucoside and 0.05 part of cetostearyl alcohol; 9.0 parts of butanediol; 0.8 part of biological sugar gum, 0.3 part of centella asiatica extract, 0.3 part of cyclodextrin, 4.0 parts of polysorbate-80, 0.20 part of glyceryl caprylate, 0.20 part of octanoyl hydroxamic acid, 0.20 part of p-hydroxyacetophenone, 0.20 part of butanediol and 70 parts of pure water.
Microemulsion efficacy emulsifier component: 15 parts of butanediol, 12 parts of hydrogenated castor oil, 2 parts of hydrogenated polyisobutene, 1 part of cetostearyl alcohol isononanoate, 20 parts of cetostearyl alcohol polyether, 3 parts of cetostearyl alcohol, 3 parts of glycerol stearate, 2 parts of cetyl palmitate, 20 parts of sodium lysinate, 2 parts of phenoxyethanol and 70 parts of pure water.
Examples
Nursing substrate components: 10.0 parts of peach leaf extract, 5.0 parts of microemulsion efficacy emulsifier, 10.0 parts of oat kernel oil, 0.10 parts of cetostearyl glucoside and 0.10 parts of cetostearyl alcohol; 10.0 parts of butanediol; 1.0 part of biological sugar gum, 0.3 part of centella asiatica extract, 0.7 part of cyclodextrin, 5.0 parts of polysorbate-80, 0.25 part of glyceryl caprylate, 0.25 part of octanoyl hydroxamic acid, 0.25 part of p-hydroxyacetophenone, 0.25 part of butanediol and 80 parts of pure water.
Microemulsion efficacy emulsifier component: 15 parts of butanediol, 15 parts of hydrogenated castor oil, 3 parts of hydrogenated polyisobutene, 3 parts of cetostearyl alcohol isononanoate, 20 parts of cetostearyl alcohol polyether, 3 parts of cetostearyl alcohol, 3 parts of glycerol stearate, 3 parts of cetyl palmitate, 20 parts of sodium lysinate, 3 parts of phenoxyethanol and 70 parts of pure water.
Volunteer actual use test: the volunteers are recruited at a gynecological clinic in a certain hospital, and the conditions of the recruited volunteers are as follows: the sanitary towel has the advantages that 100 female volunteers are recruited together, the female volunteers are randomly divided into 2 groups, 50 persons in each group are respectively a test group 1 and a test group 2, the test group 1 uses the sanitary towel manufactured in the embodiment 1-5, the test group 2 uses a foreign brand of certain antibacterial sanitary towel (protective pad) and sanitary trousers, and the number of samples is counted according to the physiological period of three months.
The sanitary towel (protective pad) and the sanitary trousers used in the test are torn off mark substances such as trademarks, the volunteer does not know why the sanitary towel (protective pad) and the sanitary trousers are used by himself, and the volunteer needs to provide own use feeling for the experimenter after menstruation is finished. The usage experience includes: whether the pudendum is fresh, whether the vagina is painful and itchy, whether the leucorrhea is reduced, whether the menstrual discomfort is slowed down, whether the user experiences friction with the sanitation, the score is 10 minutes each time, the better the feeling is, the higher the score is, and three average division of three menstrual periods of each group of volunteers is calculated. The test results are shown in the following table:
from the table data, it can be seen that: test group 1 using the sanitary napkins (pads) and the sanitary pants of examples 1 to 5 was significantly superior to test group 2 in terms of pudendum freshness, reduction of itching, reduction of menstrual discomfort, reduction of a feeling of friction with sanitation, and the like. Therefore, the sanitary towel (protective pad) prepared by using the peach She Zhicui soothing and repairing essence and the sanitary towel (protective pad) prepared by using the sanitary towel nursing base material can absorb nutrient components by the vulvar skin when in use, can strengthen the activity of skin cells and relieve the symptoms of pudendum inflammation and the like, has smooth touch after use and achieves the aims of nourishing skin and micro-ecological balance of skin.
In the description of the present specification, the terms "one embodiment," "some embodiments," "particular embodiments," and the like, mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the spirit and scope of the invention as defined by the appended claims and their equivalents.

Claims (10)

1. The peach leaf plant extract relief and repair essence disposable hygienic product nursing base material is characterized by being prepared from the following raw materials in parts by weight: 6.0 to 10.0 parts of peach leaf extract, 2.0 to 5.0 parts of microemulsion efficacy emulsifying agent, 5.0 to 10.0 parts of oat kernel oil, 0.05 to 0.2 parts of thickening agent, 5.0 to 10.0 parts of humectant, 0.1 to 1.0 part of accelerator, 0.1 to 1.0 part of sensitizer, 1.0 to 5.0 parts of solubilizer, 0.5 to 1.0 part of non-irritating preservative composition and 55 to 80 parts of pure water.
2. The care substrate according to claim 1, wherein the microemulsion efficacy emulsifier is prepared from the following raw materials in parts by weight: 10-15 parts of butanediol, 10-15 parts of hydrogenated castor oil, 1-3 parts of hydrogenated polyisobutene, 1-3 parts of cetostearyl isononanoate, 1-3 parts of cetostearyl alcohol polyether, 1-3 parts of cetostearyl alcohol, 1-3 parts of glycerol stearate, 1-3 parts of cetyl palmitate, 15-20 parts of sodium lysinate, 1-3 parts of phenoxyethanol and 60-70 parts of pure water.
3. A care substrate according to claim 1, characterized in that the thickener is a mixture of cetostearyl glucoside and cetostearyl alcohol in any ratio.
4. A care substrate according to claim 1, characterized in that the humectant is butylene glycol.
5. A care substrate according to claim 1, characterized in that the accelerator is a biose gum-1.
6. The care substrate according to claim 1, wherein the anti-sensitization agent is a mixture of centella asiatica extract and cyclodextrin in any ratio.
7. A care substrate according to claim 1, characterized in that the solubilizer is polysorbate-80.
8. A care substrate according to claim 1, characterized in that the non-irritating preservative composition is a mixture of glyceryl octanoate, octanoyl hydroxamic acid, p-hydroxyacetophenone and butylene glycol in the same proportions.
9. A method of preparing a care substrate according to any one of claims 1 to 8, characterized by the steps of:
(1) Preparation of component A: adding the peach leaf extract, the microemulsion efficacy emulsifier and the oat kernel oil in parts by weight into a stirrer A, and then mixing for 5-10 minutes at the rotating speed of 50-60 rpm to prepare a component A;
(2) Preparation of component B: adding the humectant, the accelerator, the anti-allergic agent, the solubilizer and the non-irritating antiseptic composition in parts by weight into a stirrer B, and then mixing for 5-10 minutes at the rotating speed of 50-60 rpm to prepare a component B;
(3) Mixing and discharging: adding the pure water in parts by weight into a main stirring kettle, adding the component A into the main stirring kettle, keeping the rotating speed at 50-60 rpm for stirring for 15-25 minutes, heating the main stirring kettle to 45 ℃ while stirring, adding the component B into the main stirring kettle at 45 ℃ at the rotating speed at 50-60 rpm for stirring for 5-10 minutes, adding the thickener in parts by weight into the main stirring kettle, keeping the rotating speed at 50-60 rpm, stirring for 15-25 minutes, standing, and discharging.
10. A sanitary napkin employing the nursing substrate of any one of claims 1-8, characterized by the following preparation process: spraying the peach She Zhicui relief repair essence disposable sanitary article nursing base material on a non-woven fabric on the surface layer, extruding the non-woven fabric by rollers, drying at 80-85 ℃, and drying to obtain the peach She Zhicui relief repair essence sanitary towel.
CN202310302791.2A 2023-03-27 2023-03-27 Peach leaf plant extract relieving and repairing essence disposable hygienic product nursing base material, preparation method and application Pending CN116585519A (en)

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CN202310302791.2A CN116585519A (en) 2023-03-27 2023-03-27 Peach leaf plant extract relieving and repairing essence disposable hygienic product nursing base material, preparation method and application

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