CN116456990A - 用靶向LPA的RNAi构建体治疗动脉粥样硬化性心血管疾病的方法 - Google Patents

用靶向LPA的RNAi构建体治疗动脉粥样硬化性心血管疾病的方法 Download PDF

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CN116456990A
CN116456990A CN202180074587.9A CN202180074587A CN116456990A CN 116456990 A CN116456990 A CN 116456990A CN 202180074587 A CN202180074587 A CN 202180074587A CN 116456990 A CN116456990 A CN 116456990A
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patient
rnai construct
lpa rnai
administered
weeks
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W·索恩
Z·琼斯
H·卡萨洪
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Amgen Inc
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Amgen Inc
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CN202180074587.9A 2020-11-05 2021-11-04 用靶向LPA的RNAi构建体治疗动脉粥样硬化性心血管疾病的方法 Pending CN116456990A (zh)

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US202063110309P 2020-11-05 2020-11-05
US63/110309 2020-11-05
PCT/US2021/058012 WO2022098841A1 (en) 2020-11-05 2021-11-04 METHODS FOR TREATING ATHEROSCLEROTIC CARDIOVASCULAR DISEASE WITH LPA-TARGETED RNAi CONSTRUCTS

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WO2025252223A1 (zh) * 2024-06-07 2025-12-11 迈威(上海)生物科技股份有限公司 一种抑制PCSK9基因表达的RNAi制剂及其应用
WO2026026890A1 (zh) * 2024-07-31 2026-02-05 前沿生物药业(南京)股份有限公司 用于抑制LPA基因表达的siRNA及其修饰物与应用

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WO2025252223A1 (zh) * 2024-06-07 2025-12-11 迈威(上海)生物科技股份有限公司 一种抑制PCSK9基因表达的RNAi制剂及其应用
WO2026026890A1 (zh) * 2024-07-31 2026-02-05 前沿生物药业(南京)股份有限公司 用于抑制LPA基因表达的siRNA及其修饰物与应用

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