CN116270326A - Spray liquid for sterilizing and deodorizing pets and preparation method thereof - Google Patents
Spray liquid for sterilizing and deodorizing pets and preparation method thereof Download PDFInfo
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- CN116270326A CN116270326A CN202310351983.2A CN202310351983A CN116270326A CN 116270326 A CN116270326 A CN 116270326A CN 202310351983 A CN202310351983 A CN 202310351983A CN 116270326 A CN116270326 A CN 116270326A
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- sterilizing
- deodorizing
- pets
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- 230000001954 sterilising effect Effects 0.000 title claims abstract description 56
- 239000007921 spray Substances 0.000 title claims abstract description 54
- 239000007788 liquid Substances 0.000 title claims abstract description 44
- 230000001877 deodorizing effect Effects 0.000 title claims abstract description 31
- 238000002360 preparation method Methods 0.000 title abstract description 7
- -1 polydimethylsiloxane Polymers 0.000 claims abstract description 39
- 229960000686 benzalkonium chloride Drugs 0.000 claims abstract description 38
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 34
- 239000000839 emulsion Substances 0.000 claims abstract description 26
- 239000004205 dimethyl polysiloxane Substances 0.000 claims abstract description 25
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims abstract description 25
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 claims abstract description 24
- CLAHOZSYMRNIPY-UHFFFAOYSA-N 2-hydroxyethylurea Chemical compound NC(=O)NCCO CLAHOZSYMRNIPY-UHFFFAOYSA-N 0.000 claims abstract description 23
- 229940031575 hydroxyethyl urea Drugs 0.000 claims abstract description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 22
- 239000002270 dispersing agent Substances 0.000 claims abstract description 20
- 229940100242 glycol stearate Drugs 0.000 claims abstract description 20
- 229920000059 polyethylene glycol stearate Polymers 0.000 claims abstract description 20
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 claims abstract description 18
- 239000008367 deionised water Substances 0.000 claims abstract description 17
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 17
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 8
- 239000002994 raw material Substances 0.000 claims abstract description 8
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims abstract 4
- 239000002002 slurry Substances 0.000 claims description 15
- 239000004698 Polyethylene Substances 0.000 claims description 13
- 238000000498 ball milling Methods 0.000 claims description 13
- 238000009924 canning Methods 0.000 claims description 13
- 229920003023 plastic Polymers 0.000 claims description 13
- 239000004033 plastic Substances 0.000 claims description 13
- 229920000573 polyethylene Polymers 0.000 claims description 13
- 229940051841 polyoxyethylene ether Drugs 0.000 claims description 7
- 229920000056 polyoxyethylene ether Polymers 0.000 claims description 7
- 150000002191 fatty alcohols Chemical class 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 150000003333 secondary alcohols Chemical class 0.000 claims description 2
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 18
- 239000000645 desinfectant Substances 0.000 abstract description 15
- 230000007794 irritation Effects 0.000 abstract description 12
- 230000001580 bacterial effect Effects 0.000 abstract description 10
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 210000004243 sweat Anatomy 0.000 abstract description 4
- 238000004140 cleaning Methods 0.000 abstract description 2
- 230000002045 lasting effect Effects 0.000 abstract description 2
- XIWFQDBQMCDYJT-UHFFFAOYSA-M benzyl-dimethyl-tridecylazanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 XIWFQDBQMCDYJT-UHFFFAOYSA-M 0.000 description 34
- MCMNRKCIXSYSNV-UHFFFAOYSA-N Zirconium dioxide Chemical compound O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 description 22
- 241000894006 Bacteria Species 0.000 description 17
- 238000000227 grinding Methods 0.000 description 15
- 230000000052 comparative effect Effects 0.000 description 12
- 235000001759 Citrus maxima Nutrition 0.000 description 11
- 244000276331 Citrus maxima Species 0.000 description 11
- 239000000919 ceramic Substances 0.000 description 11
- 238000012360 testing method Methods 0.000 description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 235000019645 odor Nutrition 0.000 description 5
- 239000000725 suspension Substances 0.000 description 5
- 239000000523 sample Substances 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 238000009395 breeding Methods 0.000 description 3
- 230000001488 breeding effect Effects 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 description 2
- 241000222122 Candida albicans Species 0.000 description 2
- 241000282326 Felis catus Species 0.000 description 2
- 229920002413 Polyhexanide Polymers 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 239000000159 acid neutralizing agent Substances 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 229940095731 candida albicans Drugs 0.000 description 2
- 235000019864 coconut oil Nutrition 0.000 description 2
- 239000003240 coconut oil Substances 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical compound ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 208000001840 Dandruff Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 238000013095 identification testing Methods 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 238000011056 performance test Methods 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 239000011885 synergistic combination Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
- A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/20—Air quality improvement or preservation, e.g. vehicle emission control or emission reduction by using catalytic converters
Abstract
The invention belongs to the technical field of sterilization disinfectants, and particularly relates to a spray liquid for sterilizing and deodorizing pets and a preparation method thereof. The spray liquid comprises the following raw material formula components in percentage by mass: 0.20 to 0.35 percent of benzalkonium chloride, 3 to 5 percent of hydroxyethyl urea, 0.10 to 0.2 percent of glycol stearate, 0.10 to 0.20 percent of polydimethylsiloxane emulsion, 0.05 to 0.10 percent of hydroxybenzoate, 0.05 to 0.10 percent of nonionic dispersant, 5 to 10 percent of ethanol, 0.5 to 1.5 percent of auxiliary odor removing agent and 86 to 91 percent of deionized water. The irritation of high-concentration benzalkonium chloride to the skin is avoided by the hydroxyethyl urea; the pet hair is smooth and glossy by using the synergy of glycol stearate and polydimethylsiloxane emulsion, and bacterial propagation caused by sweat adhesion to the hair is resisted, so that lasting antibacterial effect is achieved; the spray liquid for sterilizing and deodorizing the pets has simple production process and industrialized production applicability, and can be widely applied to rapid cleaning and sterilization of bodies of the pets and sterilization and disinfection of pet cages, pet mats and the like.
Description
Technical Field
The invention belongs to the technical field of sterilization disinfectants, and particularly relates to a spray liquid for sterilizing and deodorizing pets and a preparation method thereof.
Background
With the rapid development of the household pet industry, the requirements on the cleanliness and the sanitation of pets are higher and higher, and new requirements are put forward on the sterilization and odor removal technical products of the pets. The peculiar smell of the pets is mainly generated by the fact that sweat of the pets and bacteria adhered to skin and hair provide a moist propagation environment. Therefore, in addition to conventional cleansing, sterilizing the skin surface and hair of pets is a major means of removing odors.
In the prior art, hypochlorous acid disinfectant is mainly adopted for sterilizing pets. But the method mainly adopts the mode of hypochlorous acid water flushing when in use. If a spray mode is adopted, the irritating smell can be generated, and the respiratory tract can be greatly stimulated.
The portable pet sterilizing and deodorizing liquid capable of being directly sprayed is needed by people with fast-paced life demands. The benzalkonium chloride disinfectant is non-volatile and has low irritation, so that the benzalkonium chloride disinfectant becomes the first choice for spray disinfectant. The benzalkonium chloride disinfectant belongs to quaternary ammonium salt, has broad-spectrum sterilization effect, and has no obvious smell, so that the benzalkonium chloride disinfectant is dominant in the aspect of being used for quick spray sterilization. At present, the conventional benzalkonium chloride disinfectant has the concentration of less than 0.1%, is widely applied to sterilization and disinfection of skin, mucous membrane, wounds, home furnishings and the like, and has no smell and no irritation.
Chinese patent publication No. CN112088879A discloses a quaternary ammonium salt compound disinfectant and a preparation method thereof, wherein the disinfectant comprises the following components in percentage by mass: 0.09 to 0.11 percent of benzalkonium chloride, 0.01 to 0.02 percent of polyhexamethylene biguanide, 0.18 to 0.22 percent of coconut oil fatty acid diethanolamide and 0.2 percent of glycerol. The benzalkonium chloride and the polyhexamethylene biguanide are compounded into the compound disinfectant, and are ionized in aqueous solution to generate strong electropositivity, so that bacteria and viruses with negative charges can be adsorbed, and meanwhile, coconut oil fatty acid diethanolamide and glycerol are cooperatively used, so that the bacteria and viruses can be killed, and the greater danger and the environmental influence on the safety of people are avoided.
However, the sterilizing effect of benzalkonium chloride sterilizing solution is relatively poor, and particularly when spray sterilization (non-soaking) is adopted, the sterilizing effect is affected to some extent. In order to improve the sterilizing effect of the benzalkonium chloride sterilizing solution when being used for spraying pets, the concentration of the benzalkonium chloride sterilizing solution needs to be increased to be more than 0.2%, and the concentration can cause certain irritation to the skin. In view of the fact that the high-concentration benzalkonium chloride sterilizing and disinfecting liquid is used for the long-term retention of skin and hair of the pet, licking and skin irritation of the pet exist, and how to reduce the irritation to the skin while ensuring the high-concentration sterilization of the benzalkonium chloride sterilizing liquid becomes a difficult problem facing the current technicians.
Disclosure of Invention
The benzalkonium chloride disinfectant is used for sterilizing pets at a concentration of more than 0.2%, and has a large stimulus to the skin of the pets due to repeated use and long-term retention of the benzalkonium chloride disinfectant on the hair skin of the pets.
The invention aims to solve the problem of overcoming the defects of the prior art and providing the spray liquid for sterilizing and deodorizing pets.
The second technical problem to be solved by the invention is to provide a preparation method of the spray liquid.
The technical scheme adopted for solving the technical problems is that the spray liquid for sterilizing and deodorizing the pets comprises the following raw material formula components in percentage by mass: 0.20 to 0.35 percent of benzalkonium chloride, 3 to 5 percent of hydroxyethyl urea, 0.10 to 0.2 percent of glycol stearate, 0.10 to 0.20 percent of polydimethylsiloxane emulsion, 0.05 to 0.10 percent of hydroxybenzoate, 0.05 to 0.10 percent of nonionic dispersant, 5 to 10 percent of ethanol, 0.5 to 1.5 percent of auxiliary odor removing agent and 86 to 91 percent of deionized water.
The hydroxyethyl urea has good moisturizing effect on skin, avoids the stimulation of high-concentration benzalkonium chloride to the skin, has no sticky property, can keep the smoothness of pet hair, and can inhibit the growth of hair bacteria.
The glycol stearate can make the hair of the pet smooth and elastic, keep the hair lustrous and effectively resist bacteria from adhering to the hair for reproduction.
The hydroxybenzoate has antibacterial and antiseptic effects, and can not only sterilize, but also destroy the microorganism environment of pet hair skin and inhibit bacteria breeding.
The nonionic dispersing agent is at least one of secondary alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether and linear fatty alcohol polyoxyethylene ether, and can effectively promote glycol stearate and polydimethylsiloxane emulsion to be dispersed in a water system under the assistance of hot ethanol to form stable spray liquid.
The polydimethylsiloxane emulsion is an emulsion with the content of effective matters in the market of 70-80%. The polydimethylsiloxane emulsion can be stably dispersed in a water system, and the spray liquid for sterilizing and deodorizing the pet can smooth and comb the hair of the pet easily, so that the growth of hair adhesion bacteria is inhibited, and the durable antibacterial effect of the hair of the pet is maintained.
The auxiliary deodorizing agent is selected from one of pericarpium Citri Grandis extract, oleum Menthae Dementholatum and oleum Eucalypti.
The technical scheme adopted for solving the second technical problem of the invention is that the preparation method of the spray liquid for sterilizing and deodorizing pets specifically comprises the following steps:
(1) Ball milling and dispersing 0.10-0.2% glycol stearate, 0.05-0.10% hydroxybenzoate, 0.05-0.10% nonionic dispersant and 5-10% ethanol into fine slurry at 40-50 deg.c;
(2) Uniformly dispersing the fine slurry, 0.20-0.35% of benzalkonium chloride, 3-5% of hydroxyethyl urea, 0.10-0.20% of polydimethylsiloxane emulsion, 0.5-1.5% of auxiliary odor removing agent and 86-91% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
Sweat, sebum and dandruff generated by the pets are adhered to the skin and hair to form a place for bacteria to grow and reproduce, and the pets generate peculiar smell along with the aggregation of the bacteria. The spray liquid has the following preferable effects: bacteria can be killed by the high-concentration benzalkonium chloride, so that the peculiar smell of the pet is prevented; in order to avoid the irritation of high-concentration benzalkonium chloride to the skin, hydroxyethyl urea is selected to moisturize the skin, the irritation of benzalkonium chloride to the skin is avoided by protecting the skin, and meanwhile, the hydroxyethyl urea has a good smooth effect on the hair, so that compared with a conventional humectant, the hair can be well prevented from being adhered, and the bacterial growth is reduced; further, the glycol stearate and the polydimethylsiloxane emulsion assist the hair of the pet to be smooth and glossy, so that bacteria are effectively resisted from adhering to the hair for breeding, and the hair of the pet is kept to have a longer sterilization effect.
Compared with the prior art, the invention has the following beneficial effects:
1. the hydroxyethyl urea with moisture retention and smoothness is selected to avoid the irritation of high-concentration benzalkonium chloride to the skin, and meanwhile, the hydroxyethyl urea has a good smoothness effect on the hair, so that the hair adhesion is well prevented, and the bacterial growth is reduced.
2. The ethylene glycol stearate and the polydimethylsiloxane emulsion are used for assisting the hair of the pet to be glossy and smooth, so that bacterial propagation caused by sweat adhering to the hair is resisted, and the lasting antibacterial effect is achieved.
3. The use of the hydroxybenzoate for auxiliary sterilization damages the microbial environment of the hair skin of the pet and inhibits the breeding and propagation of bacteria.
4. The spray liquid for sterilizing and deodorizing the pets has stable raw material supply, simple production process and industrialized production applicability, and can be widely applied to rapid cleaning and sterilization of bodies of the pets and sterilization and disinfection of pet cages, pet pads and the like.
Detailed Description
In order that those skilled in the art will better understand the present invention, a more complete description of the same will be provided below, with the understanding that the present invention is illustrated by way of example only and not by way of limitation in all embodiments. All other embodiments obtained by those skilled in the art without making any creative effort shall fall within the protection scope of the present invention based on the technical ideas of the present invention.
In the invention, all raw materials are obtained from commercial sources unless otherwise specified, and part of raw materials are prepared as follows:
polydimethylsiloxane emulsion (brand DM-ST570, available from Guangzhou City Kolming chemical Co., ltd.) with an effective component content of 77% by mass.
Deionized water: distilled water is sterilized and disinfected.
Example 1
(1) Ball milling 0.10% of glycol stearate, 0.05% of hydroxybenzoate, 0.05% of nonionic dispersant alkylphenol ethoxylate and 6% of ethanol at 40 ℃ by using a ball mill, wherein the grinding balls of the ball mill adopt zirconia ceramic balls with the diameter of 0.5mm, grinding and dispersing for 30min, and dispersing to obtain fine slurry;
(2) Uniformly dispersing the fine pulp, 0.26% of benzalkonium chloride, 3% of hydroxyethyl urea, 0.20% of polydimethylsiloxane emulsion, 0.5% of shaddock ped extract and 89.84% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
Example 2
(1) Ball milling 0.10% of glycol stearate, 0.05% of hydroxybenzoate, 0.05% of nonionic dispersant alkylphenol ethoxylate and 6% of ethanol at 40 ℃ by using a ball mill, wherein the grinding balls of the ball mill adopt zirconia ceramic balls with the diameter of 0.5mm, grinding and dispersing for 30min, and dispersing to obtain fine slurry;
(2) Uniformly dispersing the fine pulp, 0.26% of benzalkonium chloride, 4% of hydroxyethyl urea, 0.20% of polydimethylsiloxane emulsion, 0.5% of shaddock ped extract and 88.84% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
Example 3
(1) Ball milling 0.10% of glycol stearate, 0.05% of hydroxybenzoate, 0.05% of nonionic dispersant alkylphenol ethoxylate and 5% of ethanol at 40 ℃ by using a ball mill, wherein the ball of the ball mill adopts zirconia ceramic balls with the diameter of 0.5mm, and the balls are ground and dispersed for 30min to obtain fine slurry;
(2) Uniformly dispersing the fine pulp, 0.26% of benzalkonium chloride, 5% of hydroxyethyl urea, 0.20% of polydimethylsiloxane emulsion, 0.5% of shaddock ped extract and 88.84% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
Example 4
(1) Ball milling 0.20% of glycol stearate, 0.05% of hydroxybenzoate, 0.05% of nonionic dispersant alkylphenol ethoxylate and 6% of ethanol at 40 ℃ by using a ball mill, wherein the grinding balls of the ball mill adopt zirconia ceramic balls with the diameter of 0.5mm, grinding and dispersing for 30min, and dispersing to obtain fine slurry;
(2) Uniformly dispersing the fine pulp, 0.26% of benzalkonium chloride, 3% of hydroxyethyl urea, 0.20% of polydimethylsiloxane emulsion, 0.5% of shaddock ped extract and 89.74% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
Example 5
(1) Ball milling 0.10% of glycol stearate, 0.10% of hydroxybenzoate, 0.05% of nonionic dispersant alkylphenol ethoxylate and 6% of ethanol at 40 ℃ by using a ball mill, wherein the grinding balls of the ball mill adopt zirconia ceramic balls with the diameter of 0.5mm, grinding and dispersing for 30min, and dispersing to obtain fine slurry;
(2) Uniformly dispersing the fine pulp, 0.26% of benzalkonium chloride, 3% of hydroxyethyl urea, 0.20% of polydimethylsiloxane emulsion, 0.5% of shaddock ped extract and 89.79% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
Example 6
(1) Ball milling 0.10% of glycol stearate, 0.05% of hydroxybenzoate, 0.1% of linear fatty alcohol polyoxyethylene ether serving as a nonionic dispersant and 6% of ethanol at 40 ℃ by using a ball mill, wherein the ball of the ball mill adopts zirconia ceramic balls with the diameter of 0.5mm, and the balls are ground and dispersed for 30min to obtain fine slurry;
(2) Uniformly dispersing the fine pulp, 0.26% of benzalkonium chloride, 3% of hydroxyethyl urea, 0.20% of polydimethylsiloxane emulsion, 0.5% of shaddock ped extract and 89.79% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
Comparative example 1
(1) Ball milling 0.10% of glycol stearate, 0.05% of hydroxybenzoate, 0.05% of nonionic dispersant alkylphenol ethoxylate and 6% of ethanol at 40 ℃ by using a ball mill, wherein the grinding balls of the ball mill adopt zirconia ceramic balls with the diameter of 0.5mm, grinding and dispersing for 30min, and dispersing to obtain fine slurry;
(2) Uniformly dispersing the fine pulp, 0.26% of benzalkonium chloride, 0.20% of polydimethylsiloxane emulsion, 0.5% of shaddock ped extract and 92.84% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
Comparative example 2
(1) Ball milling 0.05% of hydroxybenzoate, 0.05% of nonionic dispersant alkylphenol ethoxylate and 6% of ethanol at 40 ℃ by using a ball mill, wherein the grinding balls of the ball mill adopt zirconia ceramic balls with the diameter of 0.5mm, and the grinding balls are dispersed for 30min and become fine slurry;
(2) Uniformly dispersing the fine pulp, 0.26% of benzalkonium chloride, 3% of hydroxyethyl urea, 0.20% of polydimethylsiloxane emulsion, 0.5% of shaddock ped extract and 89.94% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
Comparative example 3
(1) Ball milling 0.10% of glycol stearate, 0.05% of nonionic dispersant alkylphenol ethoxylate and 6% of ethanol at 40 ℃ by using a ball mill, wherein the ball of the ball mill adopts zirconia ceramic balls with the diameter of 0.5mm, and the balls are ground and dispersed for 30min to obtain fine slurry;
(2) Uniformly dispersing the fine pulp, 0.26% of benzalkonium chloride, 3% of hydroxyethyl urea, 0.20% of polydimethylsiloxane emulsion, 0.5% of shaddock ped extract and 89.89% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
Comparative example 4
(1) Ball milling 0.10% glycol stearate, 0.05% hydroxybenzoate and 6% ethanol at 40deg.C by using a ball mill, wherein the ball of the ball mill adopts zirconia ceramic balls with diameter of 0.5mm, and the balls are subjected to grinding and dispersing for 30min to obtain fine slurry;
(2) Uniformly dispersing the fine pulp, 0.26% of benzalkonium chloride, 3% of hydroxyethyl urea, 0.20% of polydimethylsiloxane emulsion, 0.5% of shaddock ped extract and 89.89% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
Comparative example 5
(1) Ball milling 0.10% of glycol stearate, 0.05% of hydroxybenzoate, 0.05% of nonionic dispersant alkylphenol ethoxylate and 6% of ethanol at 40 ℃ by using a ball mill, wherein the grinding balls of the ball mill adopt zirconia ceramic balls with the diameter of 0.5mm, grinding and dispersing for 30min, and dispersing to obtain fine slurry;
(2) Uniformly dispersing the fine pulp, 0.26% of benzalkonium chloride, 3% of hydroxyethyl urea, 0.5% of shaddock ped extract and 90.04% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
The formulation table of each spray liquid is shown in table 1.
Table 1:
related experimental test:
basic performance testing of the spray solution (one) is shown in table 2.
Table 2:
as evaluated by basic performance tests, comparative example 4 spray liquor sample without nonionic dispersant had a small amount of precipitate and floc was present after heating and freezing treatment, which was subject to denaturation, mainly the absence of nonionic dispersant did not allow ethylene glycol stearate to be well dispersed in water system.
And (II) testing sterilization performance:
1. test strain: coli ATCC 25922, staphylococcus aureus ATCC 6538 and candida albicans ATCC 10231.
2. Neutralizing agent: D/E neutralization broth (neutralization agent identification test was performed according to GB 15979-2002 clause C3, evaluated as a qualified neutralization agent).
3. Disinfectant: spray liquid sample liquid example 1, comparative examples 1-5.
4. The testing method comprises the following steps: the sterilization test is carried out according to the GB 15979-2002 clause C3, 100 mu L of bacterial suspension is taken and added into the spray sample liquid, after 2min of action, 0.5mL of the bacterial suspension is absorbed and added into 4.5mL of the corresponding neutralizer, after 10min of action, the bacterial suspension is properly diluted, 0.5mL of the bacterial suspension is taken and used as a viable bacteria culture count, and meanwhile, the bacterial suspension is taken as a control sample. The bactericidal effect of the samples is shown in table 3.
Table 3:
through the test of sterilization performance, when the concentration of benzalkonium chloride exceeds 0.2 percent (0.26 percent), the spray liquid sample liquid has obvious killing effect on escherichia coli, staphylococcus aureus and candida albicans.
(III) test of irritation and sterilization durability of spray liquid to pets:
1. the spray liquid is used for sterilizing the pet cat, and the irritation of the spray liquid to the skin is judged according to the itching and the redness and swelling of the skin of the pet.
2. After the pet cat is sterilized by using the spray liquid, the bacterial regeneration condition is judged according to the peculiar smell and hair conditions of 15 days and 30 days. As shown in table 4.
Table 4:
through tests, the hydroxyethyl urea is adopted in the example 1 to avoid the irritation of high-concentration benzalkonium chloride to the skin, the dispersed glycol stearate and the polydimethylsiloxane emulsion are contained to continuously keep the hair of the pet smooth, the propagation of bacteria is inhibited, and the good synergistic effect ensures that the hair is smooth and odorless after 30 days of using the spray liquid. The spray of comparative example 1 did not contain hydroxyethylurea, and showed some itching and irritation after application to pets, and had slightly inferior hair smoothness. The spray of comparative example 2 showed poor hair smoothness after 30 days without ethylene glycol stearate, and was sticky and bacteria-developed to develop off-flavors. The spray of comparative example 3 does not use hydroxybenzoate, and the microbial environment of the hair is prone to bacteria growth after 30 days, resulting in off-flavors. The spray of comparative example 4 does not use a nonionic dispersant, and ethylene glycol stearate cannot be effectively dispersed in the spray, so that deterioration of hair smoothness occurs, and blocking and bacteria growth occur to generate odor. The spray of comparative example 5 was smooth and poor in the late hair stage without using the polydimethylsiloxane emulsion, was prone to blocking and bacteria growth, and developed off-flavors.
It is apparent that the present invention achieves the intended effect and better than the prior art by synergistic combination of raw materials, wherein the basic principle of the invention, the main characteristics of each raw material and the reason for selection are described in the embodiments, it should be understood that the present invention is not limited by the above embodiments, the above embodiments and the description are merely illustrative of the principles of the present invention, and various changes and modifications can be made in the present invention without departing from the scope of the principles of the present invention, which shall fall within the protection scope of the present invention.
Claims (5)
1. The spray liquid for sterilizing and deodorizing pets is characterized in that: the spray liquid comprises the following raw material formula components in percentage by mass: 0.20 to 0.35 percent of benzalkonium chloride, 3 to 5 percent of hydroxyethyl urea, 0.10 to 0.2 percent of glycol stearate, 0.10 to 0.20 percent of polydimethylsiloxane emulsion, 0.05 to 0.10 percent of hydroxybenzoate, 0.05 to 0.10 percent of nonionic dispersant, 5 to 10 percent of ethanol, 0.5 to 1.5 percent of auxiliary odor removing agent and 86 to 91 percent of deionized water.
2. The spray for sterilizing and deodorizing pets according to claim 1, wherein: the nonionic dispersant is at least one of secondary alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether and linear fatty alcohol polyoxyethylene ether.
3. The spray for sterilizing and deodorizing pets according to claim 1, wherein: the content of the effective matters in the polydimethylsiloxane emulsion is 70-80%.
4. The spray for sterilizing and deodorizing pets according to claim 1, wherein: the auxiliary deodorizing agent is selected from one of pericarpium Citri Grandis extract, oleum Menthae Dementholatum and oleum Eucalypti.
5. A method for preparing the spray liquid for sterilizing and deodorizing pets according to any of claims 1 to 4, characterized in that: the method specifically comprises the following steps:
(1) Ball milling and dispersing 0.10-0.2% glycol stearate, 0.05-0.10% hydroxybenzoate, 0.05-0.10% nonionic dispersant and 5-10% ethanol into fine slurry at 40-50 deg.c;
(2) Uniformly dispersing the fine slurry, 0.20-0.35% of benzalkonium chloride, 3-5% of hydroxyethyl urea, 0.10-0.20% of polydimethylsiloxane emulsion, 0.5-1.5% of auxiliary odor removing agent and 86-91% of deionized water in a dispersing machine, and canning with a polyethylene plastic bottle to obtain the spray liquid for sterilizing and deodorizing pets.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106479743A (en) * | 2016-09-22 | 2017-03-08 | 长兴净安环保科技有限公司 | A kind of house pet Sterilization detergent and preparation method thereof |
| CN109568187A (en) * | 2019-01-17 | 2019-04-05 | 威莱(广州)日用品有限公司 | A kind of pet dog multiple-effect nursing bath foam and preparation method thereof |
| CN114432175A (en) * | 2022-02-21 | 2022-05-06 | 佛山市佛丹动物药业有限公司 | Pet skin care agent |
| CN115734808A (en) * | 2020-06-30 | 2023-03-03 | 联合利华知识产权控股有限公司 | Disinfecting compositions |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106479743A (en) * | 2016-09-22 | 2017-03-08 | 长兴净安环保科技有限公司 | A kind of house pet Sterilization detergent and preparation method thereof |
| CN109568187A (en) * | 2019-01-17 | 2019-04-05 | 威莱(广州)日用品有限公司 | A kind of pet dog multiple-effect nursing bath foam and preparation method thereof |
| CN115734808A (en) * | 2020-06-30 | 2023-03-03 | 联合利华知识产权控股有限公司 | Disinfecting compositions |
| CN114432175A (en) * | 2022-02-21 | 2022-05-06 | 佛山市佛丹动物药业有限公司 | Pet skin care agent |
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