CN116211980A - Preparation for fattening and promoting growth of pigs and preparation method thereof - Google Patents
Preparation for fattening and promoting growth of pigs and preparation method thereof Download PDFInfo
- Publication number
- CN116211980A CN116211980A CN202211598367.9A CN202211598367A CN116211980A CN 116211980 A CN116211980 A CN 116211980A CN 202211598367 A CN202211598367 A CN 202211598367A CN 116211980 A CN116211980 A CN 116211980A
- Authority
- CN
- China
- Prior art keywords
- parts
- fattening
- preparation
- pigs
- growth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 38
- 241000282887 Suidae Species 0.000 title claims abstract description 32
- 230000012010 growth Effects 0.000 title claims abstract description 28
- 230000001737 promoting effect Effects 0.000 title claims abstract description 23
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims abstract description 42
- 239000003814 drug Substances 0.000 claims abstract description 27
- 239000000843 powder Substances 0.000 claims abstract description 27
- 238000000855 fermentation Methods 0.000 claims abstract description 26
- 230000004151 fermentation Effects 0.000 claims abstract description 26
- 239000004310 lactic acid Substances 0.000 claims abstract description 21
- 235000014655 lactic acid Nutrition 0.000 claims abstract description 21
- 229930010555 Inosine Natural products 0.000 claims abstract description 19
- UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 claims abstract description 19
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims abstract description 19
- 229960003786 inosine Drugs 0.000 claims abstract description 19
- 229930182817 methionine Natural products 0.000 claims abstract description 19
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000000463 material Substances 0.000 claims abstract description 12
- 241000756943 Codonopsis Species 0.000 claims abstract description 11
- 244000163122 Curcuma domestica Species 0.000 claims abstract description 11
- 235000002956 Gynostemma pentaphyllum Nutrition 0.000 claims abstract description 11
- 240000007232 Illicium verum Species 0.000 claims abstract description 11
- 235000008227 Illicium verum Nutrition 0.000 claims abstract description 11
- 241001061264 Astragalus Species 0.000 claims abstract description 10
- 235000003392 Curcuma domestica Nutrition 0.000 claims abstract description 10
- 240000006509 Gynostemma pentaphyllum Species 0.000 claims abstract description 10
- 244000234609 Portulaca oleracea Species 0.000 claims abstract description 10
- 235000001855 Portulaca oleracea Nutrition 0.000 claims abstract description 10
- 235000006533 astragalus Nutrition 0.000 claims abstract description 10
- 235000003373 curcuma longa Nutrition 0.000 claims abstract description 10
- 210000004233 talus Anatomy 0.000 claims abstract description 10
- 235000013976 turmeric Nutrition 0.000 claims abstract description 10
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 210000000582 semen Anatomy 0.000 claims abstract description 5
- 241001529744 Origanum Species 0.000 claims abstract description 3
- 235000011203 Origanum Nutrition 0.000 claims abstract description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 28
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 24
- 239000000203 mixture Substances 0.000 claims description 21
- 241000193171 Clostridium butyricum Species 0.000 claims description 16
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 16
- 235000013628 Lantana involucrata Nutrition 0.000 claims description 16
- 235000006677 Monarda citriodora ssp. austromontana Nutrition 0.000 claims description 16
- 240000007673 Origanum vulgare Species 0.000 claims description 16
- 230000001580 bacterial effect Effects 0.000 claims description 16
- 239000008103 glucose Substances 0.000 claims description 16
- 239000000284 extract Substances 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 15
- 238000002156 mixing Methods 0.000 claims description 15
- 238000007873 sieving Methods 0.000 claims description 15
- 239000000725 suspension Substances 0.000 claims description 15
- 108090000790 Enzymes Proteins 0.000 claims description 14
- 102000004190 Enzymes Human genes 0.000 claims description 14
- 235000015278 beef Nutrition 0.000 claims description 14
- 238000012258 culturing Methods 0.000 claims description 14
- 239000011780 sodium chloride Substances 0.000 claims description 14
- 230000001954 sterilising effect Effects 0.000 claims description 14
- 238000009472 formulation Methods 0.000 claims description 11
- 238000010298 pulverizing process Methods 0.000 claims description 10
- 238000001035 drying Methods 0.000 claims description 9
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims description 8
- 238000001816 cooling Methods 0.000 claims description 8
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 7
- 238000007605 air drying Methods 0.000 claims description 2
- 238000004659 sterilization and disinfection Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 18
- 210000000952 spleen Anatomy 0.000 abstract description 13
- 235000021050 feed intake Nutrition 0.000 abstract description 11
- 230000006870 function Effects 0.000 abstract description 9
- 230000036039 immunity Effects 0.000 abstract description 7
- 210000002784 stomach Anatomy 0.000 abstract description 7
- 238000010521 absorption reaction Methods 0.000 abstract description 6
- 230000000968 intestinal effect Effects 0.000 abstract description 5
- 241000721047 Danaus plexippus Species 0.000 abstract description 3
- 238000005516 engineering process Methods 0.000 abstract description 3
- 230000007413 intestinal health Effects 0.000 abstract description 3
- 235000016709 nutrition Nutrition 0.000 abstract description 3
- 230000035764 nutrition Effects 0.000 abstract description 3
- 206010059866 Drug resistance Diseases 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 description 17
- 210000001035 gastrointestinal tract Anatomy 0.000 description 16
- 229940079593 drug Drugs 0.000 description 13
- 241000894006 Bacteria Species 0.000 description 9
- 241001465754 Metazoa Species 0.000 description 9
- 241000186660 Lactobacillus Species 0.000 description 7
- 229940039696 lactobacillus Drugs 0.000 description 7
- 210000004072 lung Anatomy 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 7
- 244000063299 Bacillus subtilis Species 0.000 description 6
- 235000014469 Bacillus subtilis Nutrition 0.000 description 6
- 240000000147 Torreya grandis Species 0.000 description 6
- 235000016410 Torreya grandis Nutrition 0.000 description 6
- 210000004185 liver Anatomy 0.000 description 6
- 238000007664 blowing Methods 0.000 description 5
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 description 5
- 230000028327 secretion Effects 0.000 description 5
- 230000007812 deficiency Effects 0.000 description 4
- 238000001727 in vivo Methods 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 244000144972 livestock Species 0.000 description 4
- 230000004060 metabolic process Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 239000013558 reference substance Substances 0.000 description 4
- 208000004998 Abdominal Pain Diseases 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 210000004347 intestinal mucosa Anatomy 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 235000013372 meat Nutrition 0.000 description 3
- 230000003647 oxidation Effects 0.000 description 3
- 238000007254 oxidation reaction Methods 0.000 description 3
- 244000045947 parasite Species 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 241000193830 Bacillus <bacterium> Species 0.000 description 2
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 241000607764 Shigella dysenteriae Species 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 210000000941 bile Anatomy 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 235000012754 curcumin Nutrition 0.000 description 2
- 229940109262 curcumin Drugs 0.000 description 2
- 239000004148 curcumin Substances 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000005176 gastrointestinal motility Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000011132 hemopoiesis Effects 0.000 description 2
- 230000036737 immune function Effects 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 210000005229 liver cell Anatomy 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 150000007524 organic acids Chemical class 0.000 description 2
- 230000036407 pain Effects 0.000 description 2
- 244000144977 poultry Species 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 230000035755 proliferation Effects 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 108700012359 toxins Proteins 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 206010070545 Bacterial translocation Diseases 0.000 description 1
- 241000186000 Bifidobacterium Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 206010008479 Chest Pain Diseases 0.000 description 1
- RGJOEKWQDUBAIZ-IBOSZNHHSA-N CoASH Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCS)O[C@H]1N1C2=NC=NC(N)=C2N=C1 RGJOEKWQDUBAIZ-IBOSZNHHSA-N 0.000 description 1
- 208000002881 Colic Diseases 0.000 description 1
- 235000014375 Curcuma Nutrition 0.000 description 1
- 206010058314 Dysplasia Diseases 0.000 description 1
- 108010024636 Glutathione Proteins 0.000 description 1
- 241001065361 Gynostemma Species 0.000 description 1
- 206010049077 Hernia pain Diseases 0.000 description 1
- 239000009636 Huang Qi Substances 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 235000007265 Myrrhis odorata Nutrition 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 108010047320 Pepsinogen A Proteins 0.000 description 1
- 240000004760 Pimpinella anisum Species 0.000 description 1
- 235000012550 Pimpinella anisum Nutrition 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 108010042687 Pyruvate Oxidase Proteins 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 102000019197 Superoxide Dismutase Human genes 0.000 description 1
- 108010012715 Superoxide dismutase Proteins 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 241000488908 Torreya Species 0.000 description 1
- 241000589886 Treponema Species 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000007375 bacterial translocation Effects 0.000 description 1
- 235000014590 basal diet Nutrition 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- RGJOEKWQDUBAIZ-UHFFFAOYSA-N coenzime A Natural products OC1C(OP(O)(O)=O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 RGJOEKWQDUBAIZ-UHFFFAOYSA-N 0.000 description 1
- 239000005516 coenzyme A Substances 0.000 description 1
- 229940093530 coenzyme a Drugs 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- KDTSHFARGAKYJN-UHFFFAOYSA-N dephosphocoenzyme A Natural products OC1C(O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 KDTSHFARGAKYJN-UHFFFAOYSA-N 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 235000019621 digestibility Nutrition 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 102000038379 digestive enzymes Human genes 0.000 description 1
- 108091007734 digestive enzymes Proteins 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000037149 energy metabolism Effects 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 239000003797 essential amino acid Substances 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000010685 fatty oil Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000001156 gastric mucosa Anatomy 0.000 description 1
- 230000007661 gastrointestinal function Effects 0.000 description 1
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000007358 intestinal barrier function Effects 0.000 description 1
- 244000000074 intestinal pathogen Species 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000003859 lipid peroxidation Effects 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 230000010016 myocardial function Effects 0.000 description 1
- 230000024121 nodulation Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000000242 pagocytic effect Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920000768 polyamine Polymers 0.000 description 1
- 239000006041 probiotic Substances 0.000 description 1
- 235000018291 probiotics Nutrition 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 229940007046 shigella dysenteriae Drugs 0.000 description 1
- 230000003393 splenic effect Effects 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 210000000108 taste bud cell Anatomy 0.000 description 1
- 230000003867 tiredness Effects 0.000 description 1
- 208000016255 tiredness Diseases 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/424—Gynostemma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
Abstract
The invention discloses a preparation for fattening pigs and promoting growth and a preparation method thereof, wherein the preparation is prepared by fermenting the following raw materials in parts by weight: 5-8 parts of purslane, 8-10 parts of rhizoma atractylodis, 5-8 parts of gynostemma pentaphylla, 8-10 parts of turmeric, 5-8 parts of star anise, 3-5 parts of semen torreyae, 8-10 parts of radix codonopsis, 6-8 parts of astragalus, 2-4 parts of inosine, 3-5 parts of origanum, 3-5 parts of glutamine, 5-8 parts of methionine and 5-8 parts of lactic acid powder. The traditional Chinese medicine disclosed by the invention utilizes compatibility of monarch, minister, assistant and guide materials to improve functions of spleen and stomach, adopts a traditional Chinese medicine fermentation technology to activate activity of the traditional Chinese medicine, and simultaneously adds raw materials capable of improving immunity of organisms and promoting intestinal health into a formula to regulate intestinal environment, improve feed intake and promote nutrition absorption, so that the functions of fattening and promoting growth are achieved, and all the raw materials are safe and effective, free of residues and free of drug resistance.
Description
Technical Field
The invention belongs to the field of traditional Chinese veterinary medicines, and particularly relates to a preparation for fattening pigs and promoting growth and a preparation method thereof.
Background
In the breeding process, the feed intake is directly related to the production performance of animals, the animals can obtain needed nutrient substances through feeding, so that the requirements of self maintenance, growth and production are met, the production potential of the animals can be better exerted by improving the feed intake, and in the case of pigs, the pigs can be fattening and promote growth, and the meat yield and the meat quality are improved.
The pig feed intake is low, the growth is slow, the pig feed intake is greatly related to the intestinal health, and the intestinal tract is not only the digestive absorption organ of the pig, but also an important barrier for preventing harmful substances and pathogenic microorganisms from invading the organism. Healthy intestinal tracts include intact intestinal morphology, good immune function and balanced microbial flora. Therefore, to increase the feed intake of pigs, the effects of fattening and promoting growth are achieved, and the improvement of intestinal health is the most important link.
Disclosure of Invention
The invention aims to provide a preparation for fattening and promoting growth of pigs.
The second object of the present invention is to provide a method for preparing the above preparation.
The third aim of the invention is to provide the influence of the traditional Chinese medicine preparation on the production performance of fattening pigs.
In order to achieve the above purpose, the invention adopts the following technical scheme:
the preparation for fattening and promoting the growth of pigs comprises the following components in parts by weight: 5-8 parts of purslane, 8-10 parts of rhizoma atractylodis, 5-8 parts of gynostemma pentaphylla, 8-10 parts of turmeric, 5-8 parts of star anise, 3-5 parts of semen torreyae, 8-10 parts of radix codonopsis, 6-8 parts of astragalus, 2-4 parts of inosine, 3-5 parts of origanum, 3-5 parts of glutamine, 5-8 parts of methionine and 5-8 parts of lactic acid powder.
The fermentation broth consists of the following raw materials in parts by weight: 2-2.5 parts of glucose, 0.5-1 part of sodium chloride, 0.3-0.5 part of beef extract, 3-4 parts of SOD enzyme, 3-4 parts of clostridium butyricum and 100 parts of water.
The preparation method comprises the following steps: (1) Sterilizing glucose, sodium chloride, beef extract and water at 121deg.C for 15 min, cooling, adding SOD enzyme and clostridium butyricum, and culturing at 34-37deg.C for 24-48 hr to obtain bacterial suspension;
(2) Pulverizing the Chinese medicinal materials respectively, sieving with 40-60 mesh sieve, and mixing;
(3) Sterilizing the Chinese medicinal powder at 121deg.C for 15 min, adding lactic acid powder, adding into fermentation tank together with 100 parts of water and 40 parts of bacterial suspension, and culturing at 34-37deg.C for 48-72 hr;
(4) Drying the fermentation product until the water content is below 10%, pulverizing, sieving, adding inosine, oregano phenol, glutamine, and methionine, and mixing uniformly to obtain the product. In the step (4), the drying refers to air drying at 60 ℃.
The application method of the product comprises the following steps: mixed feeding, 400kg of the feed is mixed with each 1kg of the preparation, and the feed can be used for a long time.
Herba Portulacae, which has liver and large intestine channels, mainly contains tea phenol, alkaloid and multiple vitamins, has effects of killing parasite, removing toxic substances, clearing heat, cooling blood and inhibiting bacteria, and has good effect on digestive tract diseases.
Cang Zhu enters spleen, stomach and liver meridians. Dry dampness, invigorate spleen, expel wind, dispel cold, improve eyesight. Rhizoma atractylodis can protect gastric mucosa, regulate gastrointestinal motility and secretion, and has remarkable treatment effect on spleen deficiency animals. It also has effects in protecting liver, promoting bile secretion and excretion, and inhibiting Escherichia coli, bacillus dysenteriae, typhoid bacillus, staphylococcus aureus and various viruses. In addition, the rhizoma Atractylodis contains vitamin D, which can promote bone to absorb calcium.
Gynostemma pentaphylla enters lung, spleen and kidney meridians. Replenishing qi to invigorate the spleen, resolving phlegm to arrest cough, clearing away heat and toxic materials. Has effects in invigorating stomach, relieving inflammation, inhibiting bacteria, killing bacteria, supplementing nutrients, enhancing immunity, resisting stress, promoting growth, and improving quality of livestock products.
Curcuma rhizome enters spleen and liver meridians. Break blood and promote qi circulation, dissipate nodulation and relieve pain. Can be used for treating qi stagnation, blood stasis, chest pain, abdominal pain, traumatic injury, swelling and pain, and rheumatalgia. The main active ingredient of the curcumin is curcumin, which can repair damaged liver cells and increase secretion of bile, and has the functions of diminishing inflammation and resisting oxidation.
Anise enters liver, kidney, spleen and stomach meridians. Warm yang, dispel cold, regulate qi. For vomiting due to middle energizer and cold, colic due to cold hernia and abdominal pain, lumbago due to kidney deficiency. The star anise and the extract thereof have the functions of preserving, expelling parasites, resisting bacteria, resisting oxidation, improving immunity and resisting viruses. Has effects of promoting growth, enhancing immunity, resisting oxidation, and improving meat quality for livestock and fowl.
Semen Torreyae, enter lung, stomach and large intestine meridians to kill parasites and remove food retention, moisten lung to arrest cough, moisten dryness and relax bowels. Semen Torreyae can promote appetite and digestion, and the contained fatty oil can help the absorption of fat-soluble vitamins, improve gastrointestinal function, replenish qi and invigorate spleen, facilitate the discharge of toxins in vivo and improve immunity.
Dang Shen enters spleen and lung meridians. Tonify middle energizer and qi, strengthen spleen and lung. Can be used for treating weakness of spleen and stomach, anorexia, diarrhea, cough and asthma due to lung deficiency, tiredness, weakness, and qi deficiency. The radix codonopsis can regulate gastrointestinal motility function, resist ulcer, enhance organism immunity, enhance hematopoiesis, resist stress, etc.
Huang Qi enters lung and spleen meridians. Tonify qi and raise yang, strengthen superficies and stop sweating, induce diuresis to alleviate edema, expel toxin and pus, heal wound and promote tissue regeneration. Astragalus has the effect of promoting nucleic acid metabolism; can enhance hematopoiesis; improving myocardial function; has antioxidant and antiviral effects.
Inosine participates in nucleic acid metabolism, energy metabolism and protein synthesis in vivo, activates a pyruvate oxidase system, improves the activity of coenzyme A, and can enable tissue cells in a low-energy hypoxia state to continue metabolism. Inosine is helpful for recovering the function of damaged liver cells, and can stimulate the generation of antibodies in vivo and improve the absorption of iron by intestinal tracts.
The oregano phenol and volatile oil extracted from natural oregano have strong antibacterial, antiseptic and bactericidal functions. Has effects in preventing and controlling diarrhea and dysentery caused by intestinal bacteria such as Escherichia coli, salmonella and treponema hyopneum; improving immune response and enhancing phagocytic bacterial activity.
Glutamine, which has close relation with immune function, especially intestinal tract immune barrier function, can reduce the permeability of intestinal mucosa and accelerate the proliferation speed of intestinal mucosa epithelial cells; can reduce intestinal bacterial translocation in a disease state to maintain intestinal barrier function; is involved in the synthesis of reduced glutathione in the intestinal tract, and reduces lipid peroxidation of intestinal mucosa epithelium.
Methionine, the only amino acid containing sulfur among essential amino acids, is used almost as a synthesis of body proteins in animals, and is also decomposed in vivo by metabolism to a small extent, and is converted into important substances related to animal development. The livestock and poultry lack methionine and show dysplasia, weight loss and damaged liver and kidney functions.
Clostridium butyricum is an anaerobic gram-positive bacillus, can grow well in the anaerobic environment of the intestinal tract, can generate butyric acid, lactic acid, acetic acid and other organic acids, reduce the pH value of the intestinal tract, inhibit harmful bacteria, promote the growth and propagation of bifidobacteria, lactobacillus and other probiotics, and further promote the microecological balance of the intestinal tract. And has certain inhibiting effect on common intestinal pathogens such as escherichia coli, shigella dysenteriae and the like.
The organic acid can promote the proliferation of beneficial bacteria such as lactobacillus by reducing the pH value after entering the gastrointestinal tract of livestock and poultry, change the living environment of harmful bacteria and inhibit harmful bacteria; can reduce intestinal microbial metabolites such as ammonia gas and polyamines, and improve the internal environment and ecological environment of digestive tract; can activate pepsinogen, stimulate the secretion of digestive enzyme, improve the digestibility of feed and promote the growth of animals; it also can stimulate the oral taste bud cells of animals to increase salivary secretion, thereby increasing appetite and improving feed intake.
The traditional Chinese medicine of the invention utilizes monarch, minister, adjuvant and guide (rhizoma atractylodis and turmeric are taken as monarch drugs, radix codonopsis pilosulae and radix astragali are taken as ministerial drugs, star anise and torreya are taken as adjuvant drugs,
purslane and gynostemma pentaphylla are used as guiding drugs) to improve the functions of spleen and stomach, a traditional Chinese medicine fermentation technology is adopted to activate the activity of the traditional Chinese medicine, and raw materials capable of improving the immunity of organisms and promoting the health of intestinal tracts are added into a formula to regulate the environment of the intestinal tracts, improve the feed intake and promote the absorption of nutrition, so that the functions of fattening and promoting the growth are achieved, and all the raw materials are safe and effective, have no residue and no drug resistance.
The invention has the advantages and beneficial effects that: (1) The invention has simple use process and is suitable for being put into production; (2) The invention enhances the product effect and improves the bioavailability by using the traditional Chinese medicine fermentation technology; (3) Aiming at the characteristics of pigs, the mixture of the invention adjusts the internal environment of intestinal tracts, improves the health of the intestinal tracts, acidifies the gastrointestinal tracts, improves the feed intake and promotes the nutrition absorption, thereby achieving the effects of fattening and promoting the growth; (4) The mixture of the invention is easy to be absorbed after entering the organism, and is convenient for clinical administration, suitable for group administration, and saves manpower and material resources.
Detailed Description
The present invention will be further described by way of examples, but the scope of the present invention is not limited thereto.
Example 1 preparation of preparation for fattening and growth-promoting pigs
The components of the composition are as follows: 5g of purslane, 10g of rhizoma atractylodis, 5g of gynostemma pentaphylla, 10g of turmeric, 5g of star anise, 5g of Chinese torreya seed, 8g of radix codonopsis pilosulae, 8g of astragalus, 2g of inosine, 5g of oregano fragrant phenol, 3g of glutamine, 8g of methionine and 5g of lactic acid powder.
Fermentation liquor components: 2g of glucose, 1g of sodium chloride, 0.3g of beef extract, 4g of SOD enzyme (10 ten thousand U/g of superoxide dismutase, the same applies below), 3g of clostridium butyricum (the viable count of clostridium butyricum is more than or equal to 100 hundred million CFU/g, the same applies below), and water is added to 100g.
The preparation method comprises the following steps: (1) Sterilizing glucose, sodium chloride, beef extract and water at 121deg.C for 15 min, cooling, adding SOD enzyme and clostridium butyricum, and culturing at 37deg.C for 24 hr to obtain bacterial suspension;
(2) Pulverizing the Chinese medicinal materials respectively, sieving with 40 mesh sieve, and mixing;
(3) Sterilizing the Chinese medicinal powder at 121deg.C for 15 min, adding lactic acid powder, adding into fermentation tank together with 100g of water and 40g of bacterial suspension, and culturing at 37deg.C for 48 hr;
(4) Drying the fermentation product at 60 ℃ by blowing until the water content is below 10%, crushing, sieving with a 40-mesh sieve, adding inosine, oregano phenol, glutamine and methionine, and uniformly mixing to obtain the product.
Example 2 preparation of preparation for fattening and growth-promoting pigs
The components of the composition are as follows: 8g of purslane, 8g of rhizoma atractylodis, 8g of gynostemma pentaphylla, 8g of turmeric, 8g of star anise, 3g of Chinese torreya seed, 10g of radix codonopsis pilosulae, 6g of astragalus, 4g of inosine, 3g of oregano fragrant phenol, 5g of glutamine, 5g of methionine and 8g of lactic acid powder.
Fermentation liquor components: glucose 2.5g, sodium chloride 0.5g, beef extract 0.5g, SOD enzyme 3g, clostridium butyricum 4g, and water to 100g.
The preparation method comprises the following steps: (1) Sterilizing glucose, sodium chloride, beef extract and water at 121deg.C for 15 min, cooling, adding SOD enzyme and clostridium butyricum, and culturing at 34 deg.C for 48 hr to obtain bacterial suspension;
(2) Pulverizing the Chinese medicinal materials respectively, sieving with 60 mesh sieve, and mixing;
(3) Sterilizing the Chinese medicinal powder at 121deg.C for 15 min, adding lactic acid powder, adding into fermentation tank together with 100g of water and 40g of bacterial suspension, and culturing at 34 deg.C for 72 hr;
(4) Drying the fermentation product at 60 ℃ by blowing until the water content is below 10%, crushing, sieving with a 40-mesh sieve, adding inosine, oregano phenol, glutamine and methionine, and uniformly mixing to obtain the product.
Example 3 preparation of preparation for fattening and growth-promoting pigs
The components of the composition are as follows: 6g of purslane, 9g of rhizoma atractylodis, 7g of gynostemma pentaphylla, 9g of turmeric, 7g of star anise, 4g of Chinese torreya seed, 9g of radix codonopsis pilosulae, 7g of astragalus, 3g of inosine, 4g of oregano, 4g of glutamine, 7g of methionine and 7g of lactic acid powder.
Fermentation liquor components: glucose 2.3g, sodium chloride 0.8g, beef extract 0.4g, SOD enzyme 3.5g, clostridium butyricum 3.5g, and water to 100g.
The preparation method comprises the following steps: (1) Sterilizing glucose, sodium chloride, beef extract and water at 121deg.C for 15 min, cooling, adding SOD enzyme and clostridium butyricum, and culturing at 37deg.C for 24 hr to obtain bacterial suspension;
(2) Pulverizing the Chinese medicinal materials respectively, sieving with 40 mesh sieve, and mixing;
(3) Sterilizing the Chinese medicinal powder at 121deg.C for 15 min, adding lactic acid powder, adding into fermentation tank together with 100g of water and 40g of bacterial suspension, and culturing at 37deg.C for 72 hr;
(4) Drying the fermentation product at 60 ℃ by blowing until the water content is below 10%, crushing, sieving with a 40-mesh sieve, adding inosine, oregano phenol, glutamine and methionine, and uniformly mixing to obtain the product.
Example 4 preparation of control for pig fattening growth promoting preparation
The components of the composition are as follows: 6g of purslane, 9g of rhizoma atractylodis, 7g of gynostemma pentaphylla, 9g of turmeric, 7g of star anise, 4g of Chinese torreya seed, 9g of radix codonopsis pilosulae, 7g of astragalus, 3g of inosine, 4g of oregano, 4g of glutamine, 7g of methionine and 7g of lactic acid powder.
Fermentation liquor components: glucose 2.3g, sodium chloride 0.8g, beef extract 0.4g, bacillus subtilis 3.5g, lactobacillus 3.5g, and water to 100g.
The preparation method comprises the following steps: (1) Sterilizing glucose, sodium chloride, beef extract and water at 121deg.C for 15 min, cooling, adding lactobacillus and bacillus subtilis, and culturing at 37deg.C for 24 hr to obtain bacterial suspension;
(2) Pulverizing the Chinese medicinal materials respectively, sieving with 40 mesh sieve, and mixing;
(3) Sterilizing the Chinese medicinal powder at 121deg.C for 15 min, adding lactic acid powder, adding into fermentation tank together with 100g of water and 40g of bacterial suspension, and culturing at 37deg.C for 72 hr;
(4) Drying the fermentation product at 60 ℃ by blowing until the water content is below 10%, crushing, sieving with a 40-mesh sieve, adding inosine, oregano phenol, glutamine and methionine, and uniformly mixing to obtain the product.
Note that: the reference substance uses lactobacillus and bacillus subtilis to replace SOD enzyme and clostridium butyricum.
Example 5 preparation of control for pig fattening growth-promoting preparation
The components of the composition are as follows: 6g of purslane, 9g of rhizoma atractylodis, 7g of gynostemma pentaphylla, 9g of turmeric, 7g of star anise, 4g of Chinese torreya seed, 9g of radix codonopsis, 7g of astragalus, 3g of inosine, 4g of oregano, 4g of glutamine, 7g of methionine, 7g of lactic acid powder, 3.5g of SOD enzyme, 3.5g of clostridium butyricum and 17g of glucose.
The preparation method comprises the following steps: pulverizing the above Chinese medicinal materials respectively, sieving with 40 mesh sieve, sequentially adding inosine, oregano phenol, glutamine, methionine, lactic acid powder, SOD enzyme, clostridium butyricum, and glucose, mixing, and packaging.
Note that: the reference substance is not prepared by adopting a traditional Chinese medicine fermentation process.
Example 6 preparation of control for pig fattening growth-promoting preparation
The components of the composition are as follows: 6g of purslane, 9g of rhizoma atractylodis, 7g of gynostemma pentaphylla, 9g of turmeric, 7g of star anise, 4g of Chinese torreya seed, 9g of radix codonopsis pilosulae, 7g of astragalus, 3g of inosine, 4g of oregano, 4g of glutamine, 7g of methionine and 7g of lactic acid powder.
Fermentation liquor components: glucose 2.3g, sodium chloride 0.8g, beef extract 0.4g, bacillus subtilis 3.5g, lactobacillus 3.5g, and water to 100g.
The preparation method comprises the following steps: (1) Sterilizing glucose, sodium chloride, beef extract and water at 121deg.C for 15 min, cooling, adding lactobacillus and bacillus subtilis, and culturing at 37deg.C for 24 hr to obtain bacterial suspension;
(2) Pulverizing the Chinese medicinal materials respectively, sieving with 40 mesh sieve, and mixing;
(3) Sterilizing the Chinese medicinal powder at 121deg.C for 15 min, adding into a fermenter together with 100g of water and 40g of bacterial suspension, and culturing at 37deg.C for 72 hr;
(4) Drying the fermentation product at 60 ℃ by blowing until the water content is below 10%, crushing, sieving with a 40-mesh sieve, adding inosine, oregano phenol, glutamine, methionine and lactic acid powder, and uniformly mixing to obtain the product.
Note that: the reference substance is lactic acid powder added in the fourth step.
In the quality stability investigation process, the reference substance is found to be easy to agglomerate in the normal temperature placing process, the character is changed, the product quality is unstable, and the clinical test is not carried out. So that lactic acid powder should be added in step (3).
Example 7 Effect on pig growth
The method is carried out according to the following steps:
drug and reagent
Test drug: the formulations prepared in examples 1, 2, 3;
control drug 1: the formulation prepared in example 4
Control drug 2: the formulation prepared in example 5
(II) test method
(1) And (3) test design: pigs 200 heads with similar ages and weight of about 35kg are selected and randomly divided into 5 groups, 40 heads in each group, wherein 3 test groups and 2 control groups.
The 3 test groups and the 2 control groups were administered at an addition level of 400kg per 1000g of the mix. The specific method comprises the following steps: the free feeding, epidemic prevention and management measures are adopted to be consistent with the daily life, and 14 days is taken as a test period.
The test animals were fed a basal diet.
The observation record items are: mainly comprises average material consumption, daily gain and feed-meat ratio.
(2) Results and analysis
Table 1 daily gain, feed conversion ratio
Table 1 shows: the preparation for fattening and promoting the growth of pigs can obviously improve the production performance, the average daily gain is 795g, the daily gain of test pigs can be respectively improved by 15.2 percent and 46.14 percent compared with a control group 1 and a control group 2, the average daily feed intake is 1.91kg, the daily gain is respectively improved by 9.8 percent and 34.5 percent compared with the control group 1 and the control group 2, the average feed weight ratio is 2.41, and the daily gain is respectively reduced by 4.4 percent and 7.7 percent compared with the control group 1 and the control group 2.
Therefore, the effect of the traditional Chinese medicine by adopting the combined fermentation of SOD enzyme and clostridium butyricum is better than that of the traditional Chinese medicine by adopting the combined fermentation of bacillus subtilis and lactic acid, and the effect of the product by adopting the fermentation of the traditional Chinese medicine is obviously better than that of the traditional Chinese medicine powder.
Example 8 effects on growth of febrile pigs
The method is carried out according to the following steps:
drug and reagent
Test drug: the formulations prepared in examples 1, 2, 3;
control drug 1: the formulation prepared in example 4
Control drug 2: the formulation prepared in example 5
(II) test method
(1) And (3) test design: weaned pigs (weaned at 28 days) weaned on the same day and transferred into the nursery are selected, 24 healthy weaned pigs are selected as normal control groups, 120 weak stiff pigs in the same batch are selected and randomly divided into five groups, 24 weaned pigs in each group, and 3 test groups and 2 control groups are selected.
The 3 test groups and the 2 control groups were administered at an addition level of 400kg per 1000g of the mix. The specific method comprises the following steps: the free feeding, epidemic prevention and management measures are adopted to be consistent with the daily life, and 20 days is taken as a test period. The whole test period was 20 days.
(2) Observation and measurement items: daily gain, feed intake and feed conversion ratio.
(II) results and analysis: the results are shown in Table 2.
TABLE 2 Effect of the invention on growth performance of Weak stiff pigs
As shown in Table 2, the daily gain and feed return of the pigs for fattening and promoting growth are improved, the production performance of the pigs can be remarkably improved, the average daily gain of a test group is 0.16kg, the daily gain of the test pigs can be improved by 45.5 percent and 128.6 percent respectively compared with a control group 1 and a control group 2, the average feed conversion ratio is 2.28, and the daily gain of the test pigs is reduced by 10.9 percent and 26.7 percent respectively compared with the control group 1 and the control group 2.
Claims (7)
1. The preparation for fattening and promoting the growth of pigs is characterized by being prepared by fermenting the following raw materials in parts by weight: 5-8 parts of purslane, 8-10 parts of rhizoma atractylodis, 5-8 parts of gynostemma pentaphylla, 8-10 parts of turmeric, 5-8 parts of star anise, 3-5 parts of semen torreyae, 8-10 parts of radix codonopsis, 6-8 parts of astragalus, 2-4 parts of inosine, 3-5 parts of origanum, 3-5 parts of glutamine, 5-8 parts of methionine and 5-8 parts of lactic acid powder.
2. The method for preparing a pig fattening growth promoting preparation according to claim 1, wherein the steps are as follows:
(1) Taking glucose, sodium chloride, beef extract and water, sterilizing at high temperature, cooling, adding SOD enzyme and clostridium butyricum, and culturing at 34-37deg.C for 24-48 hr to obtain bacterial suspension;
(2) Pulverizing the Chinese medicinal materials respectively, sieving with 40-60 mesh sieve, and mixing;
(3) After the traditional Chinese medicine powder is sterilized at high temperature, adding lactic acid powder, adding 100 parts of water and 40 parts of bacterial suspension into a fermentation tank, and culturing for 48-72 hours at the constant temperature of 34-37 ℃;
(4) Drying the fermentation product until the water content is below 10%, pulverizing, sieving, adding inosine, oregano phenol, glutamine, and methionine, and mixing uniformly to obtain the product.
3. The method for preparing the pig fattening and growth promoting preparation according to claim 2, wherein in the step (1), the bacterial suspension comprises the following raw materials in parts by weight: 2-2.5 parts of glucose, 0.5-1 part of sodium chloride, 0.3-0.5 part of beef extract, 3-4 parts of SOD enzyme, 3-4 parts of clostridium butyricum and 100 parts of water.
4. The method for preparing a pig fattening and growth promoting preparation according to claim 2, wherein the high-temperature sterilization is performed at 110-130 ℃ for 10-30 minutes.
5. The method for preparing a formulation for fattening pigs according to claim 2, wherein the drying is forced air drying at 60 ℃.
6. The method of using a formulation for fattening pigs to promote growth according to claim 1, wherein the formulation is mixed with 400kg per 1kg of formulation.
7. Use of the formulation for fattening pigs according to claim 1 for fattening pigs.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211598367.9A CN116211980B (en) | 2022-12-12 | 2022-12-12 | Preparation for fattening and promoting growth of pigs and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211598367.9A CN116211980B (en) | 2022-12-12 | 2022-12-12 | Preparation for fattening and promoting growth of pigs and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN116211980A true CN116211980A (en) | 2023-06-06 |
| CN116211980B CN116211980B (en) | 2024-03-15 |
Family
ID=86577522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211598367.9A Active CN116211980B (en) | 2022-12-12 | 2022-12-12 | Preparation for fattening and promoting growth of pigs and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116211980B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110604225A (en) * | 2018-06-15 | 2019-12-24 | 江苏奥迈生物科技有限公司 | Pig intestinal health regulator and preparation method thereof |
| CN112237239A (en) * | 2020-10-13 | 2021-01-19 | 河南北农高科生物科技有限公司 | Feed additive for livestock and poultry intestinal nutrition and health and application thereof |
-
2022
- 2022-12-12 CN CN202211598367.9A patent/CN116211980B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110604225A (en) * | 2018-06-15 | 2019-12-24 | 江苏奥迈生物科技有限公司 | Pig intestinal health regulator and preparation method thereof |
| CN112237239A (en) * | 2020-10-13 | 2021-01-19 | 河南北农高科生物科技有限公司 | Feed additive for livestock and poultry intestinal nutrition and health and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN116211980B (en) | 2024-03-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110637942A (en) | Laying hen premix rich in amino acid eggs and production method and application thereof | |
| CN109527260B (en) | Compound bioactive feed additive for poultry and preparation method thereof | |
| CN107114584A (en) | The feed addictive and its making application method of a kind of milking sow | |
| CN110574840A (en) | Traditional Chinese medicine fermented feed for preventing African swine fever and preparation method thereof | |
| CN110663832A (en) | Pig feed for promoting pig growth and preparation method thereof | |
| CN111567682A (en) | Natural feed and enzyme preparation compound type functional additive and preparation method thereof | |
| CN107223792A (en) | Broiler chicken feed additive and its preparation method and application | |
| CN107333985B (en) | Pig phagostimulant and preparation method thereof | |
| CN110664896B (en) | Anti-stress sudden death prevention compound fermentation traditional Chinese medicine additive and preparation method and application thereof | |
| CN106912449B (en) | Method for raising selenium-rich broiler chickens | |
| CN116211980B (en) | Preparation for fattening and promoting growth of pigs and preparation method thereof | |
| CN103975896B (en) | Reduce the raising method of partly raising heavy metal antibiotic residue in traditional black Meat scattered | |
| CN106962644A (en) | Big swine feed of grain-saving type and preparation method thereof | |
| CN111053153A (en) | Fermented feed additive for relieving livestock and poultry influenza symptoms and preparation method thereof | |
| CN104258007B (en) | It is a kind of to be fattened somatotrophic Chinese medicine preparation and preparation method thereof for pig | |
| CN110833120A (en) | Feed and preparation method thereof | |
| CN108159199A (en) | A kind of female preparation method for increasing egg and dissipating of the benefit of composite bacteria fermentation | |
| CN108186941B (en) | Composition for promoting growth and fattening of livestock and poultry and preparation method thereof | |
| CN106937711A (en) | A kind of feed for preventing and treating hydropsy for baby pigs and preparation method thereof | |
| CN106974072A (en) | Swine feed and preparation method thereof in grain-saving type | |
| CN111713599A (en) | Feed additive and preparation method thereof | |
| CN111264711A (en) | Chinese herbal medicine fermented feed and preparation process thereof | |
| CN107494922A (en) | It is a kind of to be used to adjust Tiny ecosystem Chinese herbal feed additive of enteron aisle and preparation method thereof | |
| CN106962645A (en) | Grain-saving type compound feed for piglets and preparation method thereof | |
| CN107821822A (en) | Pig cultivation green feed additive |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |