CN116173171A

CN116173171A - Pure plant hair growth product and preparation method thereof

Info

Publication number: CN116173171A
Application number: CN202310166129.9A
Authority: CN
Inventors: 倪世阳
Original assignee: Individual
Current assignee: Individual
Priority date: 2023-02-24
Filing date: 2023-02-24
Publication date: 2023-05-30

Abstract

The invention relates to the technical field of hair growth, in particular to the field of IPC A61K8, and more particularly relates to a pure plant hair growth product and a preparation method thereof. The preparation raw materials comprise the following components in parts by weight: 24-95 parts of plant components and 50-1000 parts of water. The invention prepares the hair-growing product by compounding specific plants and adopting a specific process. The hair growth product has the functions of preventing hair loss, promoting hair growth, removing dandruff, moisturizing hair, nourishing hair and the like, is convenient to use, can be absorbed without cleaning after being smeared, adopts a pure plant formula, and has natural and safe raw material sources and no side effect.

Description

Pure plant hair growth product and preparation method thereof

Technical Field

The invention relates to the technical field of hair growth, in particular to the field of IPC A61K8, and more particularly relates to a pure plant hair growth product and a preparation method thereof.

Background

Alopecia is a phenomenon of hair loss, and normal alopecia is a phenomenon that hair of scalp is metabolized normally, hair in the withdrawal period and the rest period is removed, and dynamic balance of scalp hair is maintained. However, with the age of people and the increase of working pressure, the problem of alopecia in the current society is more and more serious, and the abnormal or excessive detachment of hair affects the health and the beauty. Abnormal hair loss is also called pathological hair loss, and mainly has various causes such as infectious hair loss, androgenetic hair loss, nervous hair loss, congenital hair loss, seasonal hair loss and the like, wherein the most common cause is hair loss caused by kidney blood deficiency, and the hair loss directly affects the life quality of people suffering from hair loss.

In the prior art, patent document with the application number of CN201911030966.9 discloses an anti-hair loss hair-growing composition, shampoo and a preparation method, and the effects of preventing hair loss and promoting hair growth are achieved by adding components such as adenosine, caffeine, plankton extracts and the like. However, adenosine and caffeine are used as chemical monomers, the target point is single, and the side effect is large.

Patent document with application number of CN201811502797.X discloses a traditional Chinese medicine hair-nourishing and hair-growing liquid containing angelica extract and a preparation method thereof, which has the effects of nourishing and growing hair through compounding a plurality of traditional Chinese medicines, but the problem of poor stability of traditional Chinese medicine components of the hair-growing liquid is not obviously improved.

Therefore, a hair-growing product with the effects of preventing hair loss, growing hair, removing dandruff, moisturizing hair and nourishing hair needs to be developed, and has the advantages of small side effect and good stability.

Disclosure of Invention

In order to solve the problems, the first aspect of the invention provides a pure plant hair growth product, which comprises the following preparation raw materials in parts by weight: 24-95 parts of plant components and 50-1000 parts of water.

Preferably, the plant component is selected from one or more of rhizoma Zingiberis recens, radix Scutellariae, radix Saposhnikoviae, fructus Vitics Simplicifoliae, radix Polygoni Multiflori, radix Paeoniae, radix Angelicae sinensis, fructus Gleditsiae Abnormalis, herba Platycladi, herba seu radix Cirsii Japonici, herba Cyathulae, rhizoma anemarrhenae, flos Lupuli, herba Swertiae Mileensis, rhizoma Ligustici Chuanxiong, hibisci, lalang grass rhizome, herba Avenae Fatuae, rhizoma Alismatis, and fructus Citri Limoniae; further preferred are Cirsium japonicum (Cirsium japonicum DC.), eclipta alba (Eclipta prostrata L.), rhizoma anemarrhenae (Anemarrhena asphodeloides Bunge), hops (Humulus lupulus L.), swertia officinalis (Swertia pseudochinensis Hara.), ligusticum chuanxiong (Ligusticum chuanxiong hort), hibiscus syriacus (Hibiscus syriacus L.), lalang grass rhizome (Rhizoma Imperatae), avena sativa L.), alisma orientalis (Alisma plantago-aquatica Linn.), and lemon (Citrus x limon (Linnaeus) Osbeck).

Preferably, the plant components comprise, in parts by weight: 2-5 parts of herba seu radix Cirsii Japonici, 3-5 parts of snakehead intestine, 3-6 parts of rhizoma anemarrhenae, 2-3 parts of hop, 3-6 parts of swertia Japonica Makino, 2-5 parts of rhizoma ligustici chuanxiong, 3-6 parts of shrubalthea, 1-3 parts of lalang grass rhizome, 1-3 parts of oat, 2-5 parts of rhizoma alismatis and 2-3 parts of lemon.

Further preferably, the plant components include, in parts by weight: 2-4 parts of herba seu radix Cirsii Japonici, 3-4 parts of snakehead intestine, 3-5 parts of rhizoma anemarrhenae, 2-3 parts of hops, 3-5 parts of swertia Japonica Makino, 2-4 parts of rhizoma ligustici chuanxiong, 3-5 parts of shrubalthea, 1-2 parts of lalang grass rhizome, 1-2 parts of oat, 2-4 parts of rhizoma alismatis and 2-3 parts of lemon.

The inventor creatively discovers that a certain amount of thistle, snakehead intestines, rhizoma anemarrhenae, hop, swertia herb, ligusticum chuanxiong, hibiscus, cogongrass rhizome, oat, rhizoma alismatis and lemon are selected as plant components, so that the hair growth and development can be promoted, and the hair blacking effect is achieved. The thistle, the snakehead intestines, the swertia herb and the shrubalthea are mixed, on one hand, the organic acid, the lactone, the picroside and the cysteine contained in the formula are synergistic, so that the hair growth and development can be promoted, the hair becomes thicker, and on the other hand, the plant components also contain nutrient components such as carotene, lutein and the like, so that nutrition can be provided for the hair, the hair can be nourished, and the hair growth can be promoted; the snakehead sausage, the hop, the sweaty medicine, the hibiscus syriacus, the cogongrass rhizome, the oat, the alisma orientale and the lemon are mixed, wherein the effective components can supplement nutrition to the hair on one hand, make the hair black and bright, effectively relieve knotted and dry hair, play a role in blackening and moistening the hair, and on the other hand, can stimulate the blood circulation of the scalp, strengthen the hair, reduce the falling of the hair, and the acidic substances in the lemon can neutralize the alkaline components in the hair to further play a role in hair care. In addition, the addition of the rhizoma anemarrhenae and the hibiscus can also clean harmful substances on the hair, such as dandruff and the like, so as to provide a clean and good environment for hair growth; the rhizoma ligustici chuanxiong extract can promote hair growth, the rhizoma anemarrhenae extract has strong inhibition effect on staphylococcus and typhoid bacteria, also has inhibition effect on other bacteria, has antipruritic and anti-dandruff effects, and reduces hair falling off caused by bacterial infection. The snakehead sausage and oat are added, so that the hair growing and nourishing effect of the product can be improved, the antioxidant effect can be achieved by inhibiting lipoxygenase, the lemon synergistic effect can be achieved, and the stability of the product can be improved.

The second aspect of the invention provides a preparation method of the pure plant hair growth product, which comprises the following steps:

s1, preparing a crude extract of plant components: extracting plant components by alcohol to obtain a crude extract of the plant components;

s2, preparing a hair growth product: mixing the crude extract of plant components with water, and filtering to obtain filtrate, which is the hair product.

Preferably, the specific process of step S1 is as follows: respectively grinding the plant components, sieving to obtain plant component powder, mixing the plant component powder according to parts by weight, drying to constant weight, adding a solvent, standing and soaking for 2-7h, performing suction filtration for 1-3 times to obtain filtrate, and performing reduced pressure distillation on the filtrate to obtain a plant component crude extract.

Preferably, the solvent is added in an amount of 5 to 10 times by weight of the plant components.

Preferably, the solvent comprises one or more of water and alcohol.

Preferably, the alcohol is one or more of a C1-C6 alkyl alcohol.

Preferably, the alcohol comprises one or more of ethanol, methanol, n-butanol, n-propanol, isopropanol, n-pentanol, 2-butanol, 2-hexanol, n-hexanol, t-butanol, 2-methyl-2-butanol; further preferred is ethanol.

Preferably, the alcohol content of the solvent is 60-90wt%.

The plant components are safe and widely available, but the extraction rate is low, and the waste of the effective components in the extraction process is serious. The inventors have unexpectedly found that the content of the plant component effective substances in the obtained hair-growing product can be increased by adding the plant component powder in a specific solvent in proportion and extracting by soaking. This is probably due to the fact that the active substances in the plant components can be dissolved in the solvent under the conditions of the present invention, thereby increasing the content of the active ingredient in the final crude extract. When the content of alcohol in the solvent is increased, although the diffusion and solubility of the active ingredient in the solvent are improved to improve the extraction rate, too high an alcohol content may cause dehydration of cells, denaturation of proteins in cells, etc., but rather inhibit the diffusion of the active ingredient, and reduce the extraction amount of the active ingredient. And although the effective components in the plant components are mostly soluble in ethanol to increase the content of the effective components in the crude extract, at the same time, impurities in the plant components such as resin, grease, pigment, etc. can be dissolved in the solvent to be extracted, and the impurities are mixed in the hair-growing product, which can block pores and influence the absorption of the scalp to the effective components, thereby influencing the performance of the hair-growing product

Preferably, the specific process of step S2 is as follows: mixing the crude extract of plant components with water, performing ultrasonic treatment at 30-40deg.C, standing at-5-10deg.C for 1-3 hr after ultrasonic treatment, taking out, centrifuging at 2000-4000r/min for 5-15min, collecting supernatant, heating to 180-280 deg.C, maintaining for 10-30min, cooling to 35-45deg.C, filtering with 50-200 mesh gauze, filtering, maintaining at 35-45deg.C, and stirring until viscosity is 20-25 mPa.s.

Preferably, the specific steps of the ultrasonic treatment are as follows: the ultrasonic time is 20-40min each time, and the ultrasonic is carried out for 1-5 times; further preferably, each time of the ultrasonic treatment is 30min, and the ultrasonic treatment is performed 3 times.

The applicant has found unexpectedly that the use of a simple aqueous extraction of the crude extract of plant components obtained allows to reduce the impurities in the product, while retaining as much as possible the active principle of the plant material, and at the same time improving the stability of the product. Through adding specific amount of water, the ultrasonic treatment and then refrigerated centrifugation, impurities with low solubility in specific solution such as resin, grease and the like can be separated out, so that the impurities in the product can be reduced, the effective components in the plant materials are reserved as much as possible, the maximization of the raw material benefit is realized, and the microbial activity in the product can be reduced through high-temperature sterilization treatment, so that the stability of the product is further improved.

The beneficial effects are that:

1. by selecting a certain amount of herba Cirsii Japonici, snakehead intestine, rhizoma anemarrhenae, hops, swertia herb, rhizoma Ligustici Chuanxiong, hibiscus syriacus, lalang grass rhizome, herba Avenae Fatuae, alismatis rhizoma and fructus Citri Limoniae as plant components, the hair growth and development can be promoted, and hair blackening effect can be achieved.

2. The stability of the pure plant hair-growing product can be improved by selecting snakehead intestines, oat and lemon.

3. The content of the plant component effective substances in the obtained hair growth product can be improved by adding the plant component powder into a specific solvent according to a certain proportion and soaking and extracting.

4. Through selecting simple water extraction method, can reduce the impurity in the product simultaneously, can also remain the active ingredient in the plant material as far as possible, can also improve the stability of product simultaneously.

5. The invention prepares the hair-growing product by compounding specific plants and adopting a specific process. The hair growth product has the functions of preventing hair loss, promoting hair growth, removing dandruff, moisturizing hair, nourishing hair and the like, is convenient to use, can be absorbed without cleaning after being smeared, adopts a pure plant formula, and has natural and safe raw material sources and no side effect.

Drawings

Fig. 1 is a scalp image before and after using example 1 of the present invention.

Detailed Description

Examples

Example 1

Example 1 provides a pure plant hair growth product, which is prepared from the following raw materials in parts by weight: 35 parts of plant components and 500 parts of water.

The plant components are herba Cirsii Japonici, eclipta, rhizoma anemarrhenae, flos Lupuli, herba Swertiae Dilutae, rhizoma Ligustici Chuanxiong, hibisci, lalang grass rhizome, herba Avenae Fatuae, alismatis rhizoma, and fructus Citri Limoniae.

The plant components comprise the following components in parts by weight: 3 parts of herba seu radix Cirsii Japonici, 4 parts of snakehead intestine, 5 parts of rhizoma anemarrhenae, 2 parts of hops, 5 parts of swertia Japonica Makino, 3 parts of rhizoma ligustici chuanxiong, 4 parts of shrubalthea, 2 parts of lalang grass rhizome, 2 parts of oat, 3 parts of rhizoma alismatis and 2 parts of lemon.

The second aspect of the embodiment provides a preparation method of the pure plant hair growth product, which comprises the following steps:

The specific process of the step S1 is as follows: respectively grinding the plant components, sieving to obtain plant component powder, mixing the plant component powder according to parts by weight, drying to constant weight, adding a solvent, standing and soaking for 5 hours, carrying out suction filtration for 2 times to obtain filtrate, and carrying out reduced pressure distillation on the filtrate to obtain the plant component crude extract.

The drying temperature was 50 ℃.

The addition amount of the solvent is 8 times of the weight parts of the plant components.

The solvent is a mixed solution of water and alcohol.

The alcohol is ethanol.

The alcohol content of the solvent was 80wt%.

The extraction time is 2h.

The mesh number of the gauze is 100 mesh.

The specific process of the step S2 is as follows: mixing the crude extract of plant components with water, performing ultrasonic treatment at 35deg.C, standing at 0deg.C for 2 hr after ultrasonic treatment, taking out, centrifuging at 3000r/min for 10min, collecting supernatant, heating to 220deg.C, maintaining for 20min, cooling to 40deg.C, filtering with 100 mesh gauze, filtering, and stirring at 40deg.C until viscosity is 20mPa.s.

Comparative example 1

Comparative example 1 provides a pure plant hair growth product, the specific embodiment is the same as example 1, except that:

the specific process of the step S2 is as follows: mixing the crude extract of plant components with water, soaking for 6h, heating to 95deg.C, decocting for 15h, cooling to 45deg.C, filtering with 200 mesh gauze, filtering, maintaining the temperature at 45deg.C, and stirring to viscosity of 20mPa.s.

Performance test method

1. Stability test

The pure plant hair growth products prepared in example 1 and comparative example 1 were placed in:

(1) storing for half a year at normal temperature (25 ℃) and indoor under the condition of dark light, observing the appearance condition of the product, and testing the viscosity, the light transmittance and the turbidity of the product;

(2) storing for 24 hours at a high temperature of 40 ℃ under indoor dark light conditions, observing the appearance condition of the product, and testing the viscosity, the light transmittance and the turbidity of the product, wherein the light transmittance and the turbidity are qualified when the error is within +/-6% and the variation of the viscosity is within +/-10% relative to the data obtained by testing under the condition (1);

(3) storing for 24 hours at a low temperature of 5 ℃ under indoor dark light conditions, observing the appearance condition of the product, and testing the viscosity, the light transmittance and the turbidity of the product, wherein the light transmittance and the turbidity are qualified when the error is within +/-6% and the variation of the viscosity is within +/-10% relative to the data obtained by testing under the condition (1);

the results of example 1 and comparative example 1 are shown in tables 1-2, respectively.

TABLE 1 stability Table of the hair growth products prepared in example 1

Performance testing	Normal temperature	High temperature	Low temperature
				Transmittance%	75	72	73
Turbidity BU	120	123	122
				Precipitation	No precipitate	Microprecipitation of	Microprecipitation of
Layering	Non-layering	Non-layering	Non-layering
				Viscosity mPas	20	22	21
Smell of	Light plant fragrance	Light plant fragrance	Light plant fragrance

TABLE 2 stability Table of the hair growth products prepared in comparative example 1

2. Hair growth test

The pure plant hair growth product prepared in example 1 was applied to the scalp of volunteers, and after one month, the hair growth of the scalp was observed, and as shown in the graph, the pure plant hair growth product prepared in example 1 of the present application has the effect of promoting hair growth.

Claims

1. The pure plant hair growth product is characterized by comprising the following raw materials in parts by weight: 24-95 parts of plant components and 50-1000 parts of water; the plant component is selected from one or more of rhizoma Zingiberis recens, radix Scutellariae, radix Saposhnikoviae, fructus Vitics Simplicifoliae, radix Polygoni Multiflori, radix Paeoniae, radix Angelicae sinensis, fructus Gleditsiae Abnormalis, herba Platycladi, herba seu radix Cirsii Japonici, snakehead intestine, rhizoma anemarrhenae, flos Lupuli, herba Swertiae Dilutae, rhizoma Ligustici Chuanxiong, hibisci, lalang grass rhizome, herba Avenae Fatuae, rhizoma Alismatis, and fructus Citri Limoniae.

2. The pure plant hair tonic product according to claim 1, wherein the plant components are thistle, snakehead, rhizoma anemarrhenae, hops, swertia, ligusticum chuanxiong, hibiscus, lalang grass rhizome, oat, rhizoma alismatis and lemon.

3. The pure plant hair tonic product according to claim 2, wherein the plant components comprise, in parts by weight: 2-5 parts of herba seu radix Cirsii Japonici, 3-5 parts of snakehead intestine, 3-6 parts of rhizoma anemarrhenae, 2-3 parts of hop, 3-6 parts of swertia Japonica Makino, 2-5 parts of rhizoma ligustici chuanxiong, 3-6 parts of shrubalthea, 1-3 parts of lalang grass rhizome, 1-3 parts of oat, 2-5 parts of rhizoma alismatis and 2-3 parts of lemon.

4. A pure plant hair growth product according to claim 3, wherein the plant components comprise, in parts by weight: 2-4 parts of herba seu radix Cirsii Japonici, 3-4 parts of snakehead intestine, 3-5 parts of rhizoma anemarrhenae, 2-3 parts of hops, 3-5 parts of swertia Japonica Makino, 2-4 parts of rhizoma ligustici chuanxiong, 3-5 parts of shrubalthea, 1-2 parts of lalang grass rhizome, 1-2 parts of oat, 2-4 parts of rhizoma alismatis and 2-3 parts of lemon.

5. A method of preparing a pure plant hair growth product according to any one of claims 1 to 4, comprising the steps of:

6. The method for preparing a pure plant hair growth product according to claim 5, wherein the specific process of step S1 is as follows: respectively grinding the plant components, sieving to obtain plant component powder, mixing the plant component powder according to parts by weight, drying to constant weight, adding a solvent, standing and soaking for 2-7h, performing suction filtration for 1-3 times to obtain filtrate, and performing reduced pressure distillation on the filtrate to obtain a plant component crude extract.

7. The method of preparing a pure plant hair growth product according to claim 6, wherein the solvent comprises one or more of water and alcohol; the alcohol is one or more of C1-C6 alkyl alcohols.

8. The method for preparing a pure plant hair growth product according to claim 7, wherein the alcohol content of the solvent is 60-90wt%.

9. The method for preparing a pure plant hair growth product according to claim, wherein the solvent is added in an amount of 5 to 10 times by weight of the plant components.

10. The method for preparing pure plant hair growth product according to claim 9, wherein the specific process of step S2 is: mixing the crude extract of plant components with water, performing ultrasonic treatment at 30-40deg.C, standing at-5-10deg.C for 1-3 hr after ultrasonic treatment, taking out, centrifuging at 2000-4000r/min for 5-15min, collecting supernatant, heating to 180-280 deg.C, maintaining for 10-30min, cooling to 35-45deg.C, filtering with 50-200 mesh gauze, filtering, maintaining at 35-45deg.C, and stirring until viscosity is 20-25 mPa.s.