CN116172198A - A health beverage prepared from Chinese herbal materials, and its preparation method - Google Patents

A health beverage prepared from Chinese herbal materials, and its preparation method Download PDF

Info

Publication number
CN116172198A
CN116172198A CN202210871239.0A CN202210871239A CN116172198A CN 116172198 A CN116172198 A CN 116172198A CN 202210871239 A CN202210871239 A CN 202210871239A CN 116172198 A CN116172198 A CN 116172198A
Authority
CN
China
Prior art keywords
parts
chinese herbal
herbal medicine
beverage
raw materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210871239.0A
Other languages
Chinese (zh)
Inventor
郑永利
郑家俊
刘志远
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Guangxin Trading Co ltd
Original Assignee
Beijing Guangxin Trading Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Guangxin Trading Co ltd filed Critical Beijing Guangxin Trading Co ltd
Priority to CN202210871239.0A priority Critical patent/CN116172198A/en
Publication of CN116172198A publication Critical patent/CN116172198A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0261—Solvent extraction of solids comprising vibrating mechanisms, e.g. mechanical, acoustical
    • B01D11/0265—Applying ultrasound
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The application relates to the technical field of beverage processing, and in particular discloses a Chinese herbal medicine health-care beverage and a preparation method thereof, wherein the Chinese herbal medicine health-care beverage comprises the following raw materials: rhizoma Polygonati, fructus Citri Sarcodactylis, mori fructus, fructus Lycii, flos Chrysanthemi, pericarpium Citri Tangerinae, poria, fructus crataegi and semen Cassiae. After the Chinese herbal medicine health drink obtained by the application is administrated by stomach infusion, the highest activities of MDA, CAT, GST and T-AOC in the liver tissue homogenate of the mice are respectively 10.69nmol/mL, 73U/mg, 100U/mg and 1.69mg/mL, and the highest activities of glutamic pyruvic transaminase and aspartic transaminase in the blood samples of the mice are respectively 177U/L and 197U/L, so that the Chinese herbal medicine health drink has higher liver nourishing and protecting effects. In addition, the swelling degree of the ears of the mice is 5.7mg at the minimum, and the anti-inflammatory effect is high.

Description

A health beverage prepared from Chinese herbal materials, and its preparation method
Technical Field
The application relates to the field of beverage processing, in particular to a Chinese herbal medicine health-care beverage and a preparation method thereof.
Background
Along with the improvement of the economic level, consumers pay more attention to self health, pay more attention to body health care, so that the market share of the functional beverage is gradually enlarged, and Chinese herbal medicines are important material sources of the functional beverage and give consideration to diet therapy. The Chinese herbal medicine health-care beverage can supplement nutrition on one hand, and on the other hand, can regulate physiological functions of people and enhance immune functions of people, and becomes a new spot in the international beverage market. The liver is one of the important organs of human body, plays a role in detoxification, plays an immune role, and has the functions of blood sugar metabolism and the like. At present, the working pressure of people is high, the phenomenon of drinking or staying up is more and more frequent, but long-term drinking and staying up can lead to the fact that the liver can not finish the excretion of toxin, and the liver is damaged. The liver is damaged, so that the detoxification function of the liver can be influenced, the content of the endotoxin in blood is greatly increased, and the health of a human body is damaged. Therefore, the development of the Chinese herbal medicine health-care raw material for protecting the liver has important significance.
Disclosure of Invention
In order to realize the liver protection and health care effects of the Chinese herbal medicine health care beverage, the application provides the Chinese herbal medicine health care beverage and a preparation method thereof.
In a first aspect, the present application provides a herbal health beverage, which adopts the following technical scheme:
a Chinese herbal medicine health-care beverage comprises the following raw materials in parts by weight: 10-20 parts of rhizoma polygonati, 4-6 parts of fingered citron, 8-10 parts of mulberry, 15-20 parts of medlar, 10-20 parts of tribute chrysanthemum, 5-10 parts of dried orange peel, 9-11 parts of poria cocos, 6-10 parts of hawthorn and 5-10 parts of semen cassiae.
The Chinese herbal medicine health-care beverage has the advantages that the raw materials of the Chinese herbal medicine health-care beverage can be selected from 10-20 parts of rhizoma polygonati, 4-6 parts of fingered citron, 8-10 parts of mulberry, 15-20 parts of medlar, 10-20 parts of tribute chrysanthemum, 5-10 parts of dried orange peel, 9-11 parts of poria cocos, 6-10 parts of hawthorn and 5-10 parts of cassia seed, the liver nourishing and anti-inflammation effects of the Chinese herbal medicine health-care beverage are higher, and when 15g of rhizoma polygonati, 5g of fingered citron, 9g of mulberry, 20g of medlar, 15g of tribute chrysanthemum, 10g of dried orange peel, 10g of poria cocos, 8g of hawthorn and 8g of cassia seed are better.
By adopting the technical scheme, the rhizoma polygonati contains extremely rich nutrients and microelements required by human body, mainly contains substances such as nicotinic acid, quinones, starch, sugar and the like, has the effects of tonifying middle-jiao and Qi, and has good effects of treating anorexia, slow-moving, dry mouth and tongue caused by weakness of spleen and stomach, listlessness, abdominal distention and stomach-yin deficiency of human body; meanwhile, the product has the effects of resisting bacteria, diminishing inflammation, nourishing yin and moisturizing lung.
The fingered citron has warm, sour, bitter and sweet nature, can enter liver and spleen channels, has the efficacy of soothing liver and regulating qi, and is suitable for symptoms such as costalgia, vexation and irritability, chest distress and discomfort, insomnia and the like caused by liver qi stagnation; it also has antiinflammatory, anticonvulsant and analgesic effects.
The mulberry contains various vitamins and carotenes which can supplement various nutrients for human bodies, contains a plurality of trace elements, can promote the hematopoietic ability of the human bodies and can improve the disease resistance of the human bodies. Secondly, mulberries are rich in various acids, such as fatty acid, malic acid and the like, and can help the intestines and stomach to digest some macromolecular substances. In addition, mulberry also contains a lot of hair blackening agents, so that hair can be blacker.
The medlar contains rich carotene, multiple vitamins, calcium, iron and other necessary nutrient substances, can improve eyesight, can also improve the immunity of the organism, strengthen the function of the organism, nourish yin and tonify kidney, has obvious inhibition effect on the generation and diffusion of cancer cells, and has the effects of strengthening the organism and delaying aging.
The flos Chrysanthemi has effects of resisting inflammation, killing bacteria, dispelling pathogenic wind, clearing heat, suppressing hyperactive liver, improving eyesight, clearing heat and detoxicating, and can be used for treating common cold, headache, giddiness, conjunctival congestion, swelling and pain, dim eyesight, etc. The dried orange peel has the effects of promoting qi circulation, eliminating dampness, stimulating appetite, and treating gastrointestinal tract digestive dysfunction due to inappetence and vomiting and diarrhea; in addition, pericarpium Citri Tangerinae has effects of eliminating dampness, eliminating dampness and phlegm, and can be used for treating cough and excessive phlegm. Poria can improve listlessness and debilitation caused by spleen qi deficiency, has good therapeutic effect on sleep disorder, insomnia and palpitation, and has immunity enhancing and antitumor effects.
Hawthorn is rich in a large amount of vitamin c and carotene. It has good effects of reducing and blocking free radical generation in human body, and thus has effects of resisting aging and enhancing immunity. Secondly, the consumption of body fat can be promoted and fat accumulation can be reduced by frequently eating the hawthorn, so that the effects of beautifying and slimming are achieved. In addition, the hawthorn has the effects of improving the immunity of the body and effectively reducing the blood fat and the blood pressure, and can prevent various cardiovascular and cerebrovascular diseases for middle-aged and elderly people with higher blood pressure or higher vascular fragility by eating a proper amount of hawthorn. Many substances contained in the composition have good effects on reducing triglyceride and cholesterol, so that the composition can prevent atherosclerosis of a human body and can effectively enhance the contractility of cardiac muscles. For many people with poor gastrointestinal functions, especially people with dyspepsia or chronic diarrhea, proper amount of hawthorn can play roles in promoting gastrointestinal peristalsis, regulating intestinal flora and improving various stomach discomforts.
Semen Cassiae has sweet, bitter and slightly cold nature, and has effects of clearing liver-fire, improving eyesight, loosening bowel to relieve constipation, and can be used for treating constipation due to liver fire and conjunctival congestion; in addition, semen Cassiae has antiinflammatory, antibacterial, serum cholesterol reducing, and blood pressure lowering effects, and can be used for preventing and treating arteriosclerosis and hypertension.
The mulberry and the medlar are taken together, can treat the symptoms of kidney deficiency, has certain curative effects on the symptoms of white head, eye flowers and the like, and has good effects on anemia and chronic liver and kidney diseases. In addition, the mulberry is rich in fatty acid, so that the decomposition of fat can be promoted, the generation of fat can be prevented, and the content of lipid in blood can be reduced. The substances can accelerate the maturation of immune cells, prevent the diffusion of cancer cells and avoid the formation of malignant tumors. Contains a plurality of fibers which are helpful for human digestion, and can effectively promote digestion and absorption of the intestines and stomach on the medlar.
Polygonatum sibiricum is combined with Lycium barbarum fruit to tonify liver and kidney, and is indicated for dizziness, soreness and weakness of waist and knees due to deficiency of liver and kidney and deficiency of essence and blood. The fingered citron and Chen Pike have the effects of strengthening spleen and promoting qi, have good effects of drying dampness and resolving phlegm, can treat the condition of spleen deficiency and abdominal distension, remove cold in the body, improve the condition of drying dampness, and have good effects of strengthening spleen. The fingered citron and the rose flowers contain rich trace element iron, promote the production of hemoglobin, improve the activity of human hematopoietic stem cells, strengthen the hematopoietic function of human bodies, and have good conditioning effects on ischemic anemia, deficiency of qi and blood, dark complexion and other symptoms of human beings. In addition, the two components are taken simultaneously, so that the antioxidant capacity of human skin is enhanced, the generation of spots, acnes and wrinkles can be prevented, the trace elements and the plant proteins contained in fingered citron and the roses with double petals can be improved, the activity of skin cells can be improved, the regeneration and the reproduction of the skin cells can be promoted, the antioxidant capacity of the skin can be improved, and the skin aging can be delayed. The bergamot and the roses with double petals are taken together, has obvious protection effect on human cardiovascular diseases, can dilate blood vessels, promote blood circulation, prevent blood pressure and blood fat from rising, contain active ingredients which can regulate human endocrine after being absorbed by human bodies, promote insulin production, ensure that human blood sugar keeps in a normal and stable state, prevent blood sugar from rising and prevent hyperglycemia from occurring.
Poria cocos and semen cassiae are taken simultaneously, so that the effects of improving the physical weakness and relieving the qi deficiency can be achieved, and the disease resistance of organisms can be effectively improved. Fructus Lycii and semen Cassiae can relieve blurred vision, and can reduce blood pressure and protect blood vessel to a certain extent. The medlar and the tribute chrysanthemum have nourishing effect on liver and kidney, and can further improve liver protection effect. The medlar and the mulberry not only can supplement abundant and comprehensive nutrition for organisms, but also can relieve some uncomfortable symptoms caused by deficiency of liver-yin and kidney-yin.
The Chinese herbal medicine health-care beverage with the effects of protecting liver, detoxifying and diminishing inflammation is obtained through the mutual matching of the raw materials.
As preferable: a Chinese herbal medicine health-care beverage comprises the following raw materials in parts by weight: 13-18 parts of rhizoma polygonati, 4.5-5.5 parts of fingered citron, 8.5-9.5 parts of mulberry, 18-20 parts of medlar, 13-18 parts of tribute chrysanthemum, 8-10 parts of dried orange peel, 9.5-10.5 parts of poria cocos, 7-9 parts of hawthorn and 7-9 parts of semen cassiae.
As preferable: the health herbal beverage also comprises the following raw materials in parts by weight: 6-8 parts of rose with heavy petals, 0.5-1.5 parts of dandelion and 0.3-0.7 part of gardenia.
The Chinese herbal medicine health-care beverage has the advantages that the raw materials of the Chinese herbal medicine health-care beverage can be selected from 10-20 parts of rhizoma polygonati, 4-6 parts of fingered citron, 8-10 parts of mulberry, 15-20 parts of medlar, 10-20 parts of tribute chrysanthemum, 5-10 parts of dried orange peel, 9-11 parts of poria cocos, 6-10 parts of hawthorn, 5-10 parts of semen cassiae, 6-8 parts of rose with heavy petals, 0.5-1.5 parts of dandelion and 0.3-0.7 part of gardenia, and the effects of liver nourishing and inflammation diminishing of the Chinese herbal medicine health-care beverage are high when 15g of rhizoma polygonati, 5g of fingered citron, 9g of mulberry, 16.5g of medlar, 15g of tribute chrysanthemum, 7g of dried orange peel, 10g of poria cocos, 8g of hawthorn, 6g of semen cassiae, 7g of rose with heavy petals, 1g of dandelion and 0.5g of gardenia are good.
By adopting the technical scheme, the rose with the thick petals has the effects of maintaining beauty, keeping young, soothing liver, removing fire, promoting blood circulation, removing blood stasis and calming emotion. Can promote the body to calm, warm and nourish liver blood and heart vessels, and has the functions of pacifying and tranquilizing, and can resist depression.
Dandelion has the effects of clearing heat and detoxicating, resolving carbuncles and resolving masses, invigorating stomach and promoting bile flow, resisting ulcer, promoting diuresis and treating stranguria, and dandelion also has the effects of clearing liver and improving vision, and is used for conjunctival congestion and swelling and pain caused by liver fire flaming.
Fructus Gardeniae has effects of relieving constipation, relieving vexation, promoting digestion, relieving fever, promoting diuresis, and soaking water in fructus Gardeniae can calm emotion, promote metabolism, relieve throat pain, excessive phlegm, and cough, and can supplement water and energy required by human body, improve gas color, and resist oxidation.
The florists chrysanthemum and the heavy-petal roses are taken simultaneously, and have good conditioning and treating effects on irregular menstruation, leucorrhea with reddish discharge, dry mouth and bitter taste, dry eyes, stuffiness and pain of two ribs or discomfort of gall area, initial sore and furuncle, traumatic injury and other diseases, and also have good conditioning and treating effects on epigastric distending pain caused by oesophageal spasm, liver depression and internal heat symptoms of the body.
As preferable: the health herbal beverage also comprises the following raw materials in parts by weight: 5-10 parts of kadsura longepedunculata ethanol extract and 0.1-0.3 part of carboxylated chitosan.
In the application, when the health herbal beverage raw materials are selected from 15g of rhizoma polygonati, 5g of fingered citron, 9g of mulberry, 20g of medlar, 15g of tribute chrysanthemum, 10g of dried orange peel, 10g of poria cocos, 8g of hawthorn and 8g of cassia seed, 7g of kadsura longepedunculata ethanol extract and 0.2g of carboxylated chitosan, the liver nourishing and anti-inflammatory effects of the health herbal beverage can be improved.
By adopting the technical scheme, the kadsura longepedunculata alcohol extract is rich in lignans, has the effects of protecting liver cell membranes, resisting lipid peroxidation, promoting protein biosynthesis, resisting bacteria, diminishing inflammation, promoting liver glycogen generation and the like, and can promote the repair, growth and inhibition of hepatic cytopathy of injured hepatic cells. In addition, the schisandra chinensis alcohol extract can promote detoxification of the liver, protect the liver from poisoning, and regenerate liver tissues damaged by abuse of alcohol, medicines or hepatitis.
Carboxylated chitosan is added as an absorbent, so that the adhesive tape below spleen cells on the small intestine can be opened, and the absorption of hydrophilic macromolecular substances in the small intestine is improved; in addition, carboxylated chitosan can open the connection structure at any time and reversibly, so that the permeability of the cell side is improved, and the absorption of the cell side line is enhanced.
As preferable: the kadsura longepedunculata alcohol extract is obtained through the following operation steps: drying fructus Schisandrae Sphenantherae at 50-60deg.C for 4-5 hr, and pulverizing to 60-70 mesh to obtain fructus Schisandrae Sphenantherae powder;
adding distilled monoglyceride into 80-90% ethanol solution, wherein the dosage of distilled monoglyceride is 1-3% of the mass of ethanol solution, and stirring to obtain ethanol mixed solution;
the feed liquid ratio is 1: (8-10), adding the kadsura longepedunculata powder into the ethanol mixed solution, carrying out ultrasonic treatment for 10min, centrifuging, collecting supernatant, drying and concentrating to obtain the kadsura longepedunculata ethanol extract.
By adopting the technical scheme, the distilled monoglyceride is added into the ethanol mixed solution as the emulsifier, so that the method has a higher emulsifying effect, and the extraction rate of the kadsura longepedunculata alcohol extracted lignans is improved.
As preferable: and petroleum ether accounting for 8-12% of the mass of the ethanol solution is also added into the ethanol mixed solution.
By adopting the technical scheme, petroleum ether is added into the ethanol mixed solution as a solvent, so that the extraction rate of the schisandra chinensis ethanol extract is improved, and meanwhile, the purity of the schisandra chinensis ethanol extract is also improved, and the ethanol extraction effect of the schisandra chinensis can be further improved.
As preferable: the method for modifying the kadsura longepedunculata alcohol extract comprises the following operation steps:
heating olive oil to 80-90 ℃ according to the mass ratio of kadsura longepedunculata ethanol extract to olive oil of 1: adding kadsura longepedunculata ethanol extract in the ratio of (40-60), stirring and dissolving, and preserving heat to 65-75 ℃ to obtain an oil phase solution;
heating purified water to 65-75 ℃, and mixing soybean lecithin and purified water according to a mass ratio of 1: adding soybean lecithin in the proportion of (35-45), emulsifying for 15-20min, maintaining the temperature to 50-60 ℃, and stirring for 40-50min to obtain aqueous phase solution;
mixing the oil phase solution and the aqueous phase solution according to the mass ratio of 1: mixing the components (2-3), adding tween 20 accounting for 5% of the volume of the olive oil, homogenizing until the particle size of oil drops in water is 40-60nm, and obtaining the modified kadsura longepedunculata alcohol extract.
By adopting the technical scheme, the kadsura longepedunculata alcohol extract is subjected to oil-in-water drop coating modification, so that the absorption effect of a human body on lignans can be improved, and the effect of lignans on liver nourishing and protecting can be improved. The soybean lecithin is selected as an emulsifier to be added, after the oil phase and the water phase are mixed, the kadsura longepedunculata ethanol extract in the oil phase is wrapped by the soybean lecithin and the water solution to form an oil-in-water drop shape, so that the digestion and absorption of the kadsura longepedunculata ethanol extract by intestines and stomach are facilitated, and the effects of nourishing liver and diminishing inflammation of the beverage are improved. In addition, the modified kadsura longepedunculata ethanol extract is stable, and is stable after being added into the concentrated solution, and no demulsification phenomenon occurs.
As preferable: the health herbal beverage also comprises the following raw materials in parts by weight: 5-7 parts of trigeminal gold.
In the application, when 15g of rhizoma polygonati, 5g of fingered citron, 9g of mulberry, 20g of medlar, 15g of tribute chrysanthemum, 10g of dried orange peel, 10g of poria cocos, 8g of hawthorn, 8g of cassia seed and 6g of trigeminal gold are selected as raw materials of the health-care herbal beverage, the liver nourishing and anti-inflammatory effects of the health-care herbal beverage can be improved.
By adopting the technical scheme, the trigeminal gold utensil has good pharmacological activities of anti-inflammation, anti-tumor, antibacterial, liver protection and the like, and can further improve the liver protection and liver nourishing effects of the beverage.
In a second aspect, the present application provides a method for preparing any one of the above-mentioned herbal health beverages, which is specifically implemented by the following technical scheme:
a preparation method of a Chinese herbal medicine health-care beverage comprises the following operation steps:
pulverizing the raw materials of the Chinese herbal medicine health beverage to 40-50 meshes for standby;
mixing purified water and crushed Chinese herbal medicine health-care beverage raw materials according to the total weight of the raw materials and 1% of purified water: mixing (15-25), heating at 100-120deg.C for 15-20min,30-150 meshes, collecting filtrate, cooling to 20+ -5deg.C, separating and removing impurities, filtering to 280-320 meshes, concentrating, sterilizing at 130-140deg.C under high temperature, and cooling to obtain concentrated solution;
adding 80-90deg.C purified water to 1000mL, stirring for dissolving, filtering, collecting filtrate, and sterilizing at 130-140deg.C to obtain Chinese herbal medicine health beverage.
As preferable: pulverizing the raw materials of the Chinese herbal medicine health beverage to 40-50 meshes for standby;
mixing purified water and crushed Chinese herbal medicine health-care beverage raw materials according to the total weight of the raw materials and 1% of purified water: mixing (15-25), heating at 80-90deg.C for 15-20min, collecting filtrate, cooling to 20+ -5deg.C, separating and removing impurities, filtering to 280-320 mesh, concentrating, sterilizing at 95-100deg.C, and cooling to obtain concentrated solution;
adding modified kadsura longepedunculata ethanol extract into the concentrated solution, adding purified water of 80-90 ℃ to 1000mL, stirring for dissolving, filtering, collecting filtrate, and sterilizing at high temperature of 95-100 ℃ to obtain the Chinese herbal medicine health beverage.
In summary, the present application includes at least one of the following beneficial technical effects:
(1) According to the application, by adjusting the formula of the Chinese herbal medicine health-care beverage, the highest activities of MDA, CAT, GST and T-AOC in liver tissue homogenate of mice are respectively 10.25nmol/mL, 50U/mg, 80U/mg and 1.42mg/mL after the administration by stomach irrigation; the highest activity of glutamic pyruvic transaminase and aspartic transaminase in the mouse blood sample is 150U/L and 170U/L respectively; in addition, the swelling degree of the ears of the mice is 7.0mg at the minimum, and the liver nourishing and detoxifying and anti-inflammatory effects are high.
(2) According to the application, on the basis of the original raw materials of the Chinese herbal medicine health-care beverage, the flos rosae rugosae, the dandelion and the gardenia are added, and after the stomach is irrigated, the highest activities of MDA, CAT, GST and T-AOC in the liver tissue homogenate of the mice are respectively 10.31nmol/mL, 51U/mg, 82U/mg and 1.44mg/mL; the highest activity of glutamic pyruvic transaminase and aspartic transaminase in the mouse blood sample is 151U/L and 172U/L respectively; in addition, the swelling degree of the ears of the mice is minimum of 6.9mg, and the effects of nourishing the liver, removing toxicity and diminishing inflammation are further improved.
(3) According to the application, the schisandra fruit alcohol extract and carboxylated chitosan are added into the raw materials of the Chinese herbal medicine health-care beverage, the mixing amount of the schisandra fruit alcohol extract and the carboxylated chitosan is regulated, and the activity of MDA, CAT, GST and T-AOC in the liver tissue homogenate of a mouse is respectively 10.35nmol/mL, 54U/mg, 85U/mg and 1.47mg/mL at most after the stomach is irrigated; the highest activity of glutamic pyruvic transaminase and aspartic transaminase in the mouse blood sample is 153U/L and 175U/L respectively; in addition, the swelling degree of the ears of the mice is minimum of 6.7mg, and the effects of nourishing the liver, removing toxicity and diminishing inflammation are further improved.
(4) According to the method, after the modifying method of the kadsura longepedunculata ethanol extract is regulated, the highest activities of MDA, CAT, GST and T-AOC in liver tissue homogenate of a mouse are respectively 10.65nmol/mL, 69U/mg, 98U/mg and 1.65mg/mL; the highest activity of glutamic pyruvic transaminase and aspartic transaminase in the mouse blood sample is 173U/L and 193U/L respectively; in addition, the swelling degree of the ears of the mice is at least 6.0mg, and the effects of nourishing the liver, removing toxicity and diminishing inflammation are further improved.
(5) According to the method, after the trigeminal gold is added into the raw materials and is subjected to gastric lavage, the highest activities of MDA, CAT, GST and T-AOC in the liver tissue homogenate of the mice are respectively 10.69nmol/mL, 73U/mg, 100U/mg and 1.69mg/mL; the highest activity of glutamic pyruvic transaminase and aspartic transaminase in the mouse blood sample is 177U/L and 197U/L respectively; in addition, the swelling degree of the ears of the mice is 5.7mg at the minimum, and the effects of nourishing the liver, removing toxicity and diminishing inflammation are further improved.
Detailed Description
The present application is described in further detail below in connection with specific examples.
All raw materials in the application are commercially available food-grade raw material products, so that all raw materials in the application are fully disclosed, and the raw materials are not limited by sources of the raw materials, and specifically: rhizoma polygonati, cylindrical in root stem, and with origin of Yunnan; fingered citron, origin is Guangdong; the mulberry is produced in the origin of Anhui; the original place of the medlar is Ningxia; the origin of the tribute chrysanthemum is Anhui; dried orange peel, the origin is Guangdong; poria cocos is originally produced in Yunnan; the hawthorn is produced in the origin of Anhui; semen Cassiae, original place of origin India; rose flowers with heavy petals, indian Pingyin in origin; dandelion, inner mongolia of origin; gardenia jasminoides ellis, original places of origin Jiangxi; the kadsura longepedunculata ethanol extract has a grain size of 100 meshes; carboxylated chitosan, carboxylation degree 80%; soybean lecithin with a particle size of 80 meshes; trigeminal gold, guangxi of origin.
Preparation example 1
The kadsura longepedunculata alcohol extract of preparation example 1 is prepared by the following method:
mixing 200g of kadsura longepedunculata with 1.2L of 95% ethanol, heating and reflux-extracting for 3h each time, filtering, collecting filtrate, removing ethanol under reduced pressure, and concentrating to obtain kadsura longepedunculata ethanol extract.
Preparation example 2
The kadsura longepedunculata alcohol extract of preparation example 2 is prepared by the following method:
drying 200g of kadsura longepedunculata at 60 ℃ for 4 hours, and crushing to 60 meshes to obtain kadsura longepedunculata powder;
adding 30g of distilled monoglyceride into 1L of ethanol solution with the volume fraction of 80%, and uniformly stirring to obtain an ethanol mixed solution; adding 100g of kadsura longepedunculata powder into 800mL of ethanol mixed solution, carrying out ultrasonic treatment for 10min, centrifuging, collecting supernatant, drying and concentrating to obtain kadsura longepedunculata ethanol extract.
Preparation example 3
The kadsura longepedunculata alcohol extract of preparation example 3 is prepared by the following method:
drying 200g of kadsura longepedunculata at 60 ℃ for 4 hours, and crushing to 60 meshes to obtain kadsura longepedunculata powder;
adding 30g of distilled monoglyceride into 1L of ethanol solution with the volume fraction of 80%, and uniformly stirring to obtain an ethanol mixed solution; 100g of kadsura longepedunculata powder is added into 900mL of ethanol mixed solution, ultrasonic treatment is carried out for 10min, centrifugation is carried out, supernatant fluid is collected, drying and concentration are carried out, and kadsura longepedunculata ethanol extract is obtained.
Preparation example 4
The kadsura longepedunculata alcohol extract of preparation example 4 is prepared by the following method:
drying 200g of kadsura longepedunculata at 60 ℃ for 4 hours, and crushing to 60 meshes to obtain kadsura longepedunculata powder;
adding 30g of distilled monoglyceride into 1L of ethanol solution with the volume fraction of 80%, and uniformly stirring to obtain an ethanol mixed solution; adding 100g of kadsura longepedunculata powder into 100mL of ethanol mixed solution, carrying out ultrasonic treatment for 10min, centrifuging, collecting supernatant, drying and concentrating to obtain kadsura longepedunculata ethanol extract.
Preparation example 5
The kadsura longepedunculata alcohol extract of preparation example 5 is prepared by the following method:
drying 200g of kadsura longepedunculata at 60 ℃ for 4 hours, and crushing to 60 meshes to obtain kadsura longepedunculata powder;
adding 30g of distilled monoglyceride and 80g of petroleum ether into 1L of ethanol solution with the volume fraction of 80%, and uniformly stirring to obtain an ethanol mixed solution;
100g of kadsura longepedunculata powder is added into 900mL of ethanol mixed solution, ultrasonic treatment is carried out for 10min, centrifugation is carried out, supernatant fluid is collected, drying and concentration are carried out, and kadsura longepedunculata ethanol extract is obtained.
Preparation example 6
The modified kadsura longepedunculata alcohol extract of preparation example 6 is prepared by the following method:
drying 200g of kadsura longepedunculata at 60 ℃ for 4 hours, and crushing to 60 meshes to obtain kadsura longepedunculata powder;
adding 30g of distilled monoglyceride and 80g of petroleum ether into 1L of ethanol solution with the volume fraction of 80%, and uniformly stirring to obtain an ethanol mixed solution;
adding 100g of kadsura longepedunculata powder into 900mL of ethanol mixed solution, carrying out ultrasonic treatment for 10min, centrifuging, collecting supernatant, drying and concentrating to obtain kadsura longepedunculata ethanol extract;
heating 5L of olive oil to 90 ℃, adding 100g of kadsura longepedunculata ethanol extract, stirring for dissolution, and preserving heat to 70 ℃ to obtain an oil phase solution;
heating 10L purified water to 70deg.C, adding 250g soybean lecithin, emulsifying for 20min, maintaining the temperature to 50deg.C, and stirring for 50min to obtain aqueous phase solution;
mixing 5L of oil phase solution with 5L of water phase solution, adding 500mL of Tween 20, homogenizing until the particle size of oil in water drops is 50nm, and obtaining the modified kadsura longepedunculata alcohol extract.
Preparation example 7
The modified kadsura longepedunculata alcohol extract of preparation example 7 is prepared by the following method:
drying 200g of kadsura longepedunculata at 60 ℃ for 4 hours, and crushing to 60 meshes to obtain kadsura longepedunculata powder;
adding 30g of distilled monoglyceride and 80g of petroleum ether into 1L of ethanol solution with the volume fraction of 80%, and uniformly stirring to obtain an ethanol mixed solution;
adding 100g of kadsura longepedunculata powder into 900mL of ethanol mixed solution, carrying out ultrasonic treatment for 10min, centrifuging, collecting supernatant, drying and concentrating to obtain kadsura longepedunculata ethanol extract;
heating 5L of olive oil to 90 ℃, adding 100g of kadsura longepedunculata ethanol extract, stirring for dissolution, and preserving heat to 70 ℃ to obtain an oil phase solution;
heating 10L purified water to 70deg.C, adding 250g soybean lecithin, emulsifying for 20min, maintaining the temperature to 50deg.C, and stirring for 50min to obtain aqueous phase solution;
mixing 5L of oil phase solution with 10L of water phase solution, adding 500mL of Tween 20, homogenizing until the particle size of oil in water drops is 50nm, and obtaining the modified kadsura longepedunculata alcohol extract.
Preparation example 8
The modified kadsura longepedunculata alcohol extract of preparation example 8 is prepared by the following method:
drying 200g of kadsura longepedunculata at 60 ℃ for 4 hours, and crushing to 60 meshes to obtain kadsura longepedunculata powder;
adding 30g of distilled monoglyceride and 80g of petroleum ether into 1L of ethanol solution with the volume fraction of 80%, and uniformly stirring to obtain an ethanol mixed solution;
adding 100g of kadsura longepedunculata powder into 900mL of ethanol mixed solution, carrying out ultrasonic treatment for 10min, centrifuging, collecting supernatant, drying and concentrating to obtain kadsura longepedunculata ethanol extract;
heating 5L of olive oil to 90 ℃, adding 100g of kadsura longepedunculata ethanol extract, stirring for dissolution, and preserving heat to 70 ℃ to obtain an oil phase solution;
heating 20L purified water to 70deg.C, adding 500g soybean lecithin, emulsifying for 20min, maintaining the temperature to 50deg.C, and stirring for 50min to obtain aqueous phase solution;
mixing 5L of oil phase solution with 15L of water phase solution, adding 500mL of Tween 20, homogenizing until the particle size of oil in water drops is 50nm, and obtaining the modified kadsura longepedunculata alcohol extract.
Preparation example 9
The modified kadsura longepedunculata alcohol extract of preparation example 9 is prepared by the following method:
oven drying 300g of fructus Schisandrae Sphenantherae at 60deg.C for 4 hr, and pulverizing to 60 mesh to obtain fructus Schisandrae Sphenantherae powder;
adding 30g of distilled monoglyceride and 80g of petroleum ether into 1L of ethanol solution with the volume fraction of 80%, and uniformly stirring to obtain an ethanol mixed solution;
adding 300g of kadsura longepedunculata powder into 2.7L of ethanol mixed solution, carrying out ultrasonic treatment for 10min, centrifuging, collecting supernatant, drying and concentrating to obtain kadsura longepedunculata ethanol extract;
heating 10L of olive oil to 90 ℃, adding 200g of kadsura longepedunculata ethanol extract, stirring for dissolution, and preserving heat to 70 ℃ to obtain an oil phase solution;
heating 5L purified water to 70deg.C, adding 250g soybean lecithin, emulsifying for 20min, maintaining the temperature to 50deg.C, and stirring for 50min to obtain aqueous phase solution;
mixing 10L of oil phase solution with 5L of water phase solution, adding 500mL of Tween 20, homogenizing until the particle size of oil in water drops is 50nm, and obtaining the modified kadsura longepedunculata alcohol extract.
Example 1
The Chinese herbal medicine health-care beverage of the embodiment 1 is prepared by the following method:
pulverizing 15g of rhizoma polygonati, 5g of fingered citron, 9g of mulberry, 20g of medlar, 15g of tribute chrysanthemum, 10g of dried orange peel, 10g of poria cocos, 8g of hawthorn and 8g of semen cassiae to 50 meshes, and uniformly mixing for later use;
adding pulverized Chinese herbal medicine health beverage raw materials into 2L purified water, heating at 100deg.C for 20min, collecting filtrate, cooling to 23deg.C, separating and removing impurities, filtering to 300 mesh, concentrating, sterilizing at 130deg.C, and cooling to obtain concentrated solution;
adding 85 ℃ purified water to 1000mL of the concentrated solution, stirring and dissolving, filtering, collecting filtrate, and sterilizing at 130 ℃ to obtain the Chinese herbal medicine health-care beverage.
Example 2
The Chinese herbal medicine health-care beverage of the embodiment 2 is completely the same as the preparation method of the embodiment 1, except that 7g of heavy-petal rose, 1g of dandelion and 0.5g of gardenia are also added into the raw materials, the mixing amount of medlar is 16.5g, the dried orange peel is 7g, the semen cassiae is 6g, and the rest mixing amount is the same as the embodiment 1.
Example 3
The Chinese herbal medicine health beverage of example 3 is identical to the preparation method of example 2, except that kadsura longepedunculata ethanol extract and carboxylated chitosan prepared in preparation example 1 are also added into the raw materials, and the specific blending amount is shown in Table 1.
Examples 4 to 5
The herbal health drink of examples 4-5 is identical to the preparation method and the raw material type of example 3, except that the blending amounts of the raw materials are different, and the details are shown in Table 1.
Table 1 mixing amount of each raw material (unit: g) of the Chinese herbal medicine health drink of examples 3-5
Raw materials Example 3 Example 4 Example 5
Polygonatum sibiricum 15 15 15
Chinese wolfberry fruit 16.5 16.5 16.5
Flos Chrysanthemi 15 15 15
Dried orange peel 7 7 7
Poria cocos 10 10 10
Hawthorn fruit 8 8 8
Semen cassiae 6 6 6
Mulberry fruit 9 9 9
Buddha's hand 5 5 5
Heavy-petal rose 7 7 7
Dandelion 1 1 1
Gardenia jasminoides ellis 0.5 0.5 0.5
Alcohol extract of kadsura longepedunculata 5 7 10
Carboxylated chitosan 0.2 0.2 0.2
Examples 6 to 13
The Chinese herbal medicine health beverage of examples 6-13 is identical to the preparation method and the raw material types of example 4, except that the kadsura longepedunculata alcohol extract prepared in preparation examples 2-9 is selected and used respectively, and the modified kadsura longepedunculata alcohol extract prepared in preparation examples 6-9 is directly added into the concentrated solution without crushing, purified water of 85 ℃ is added to 1000mL, the mixture is stirred and dissolved, the mixture is filtered, the filtrate is collected, and the mixture is sterilized at a high temperature under the condition of 95 ℃ to obtain the Chinese herbal medicine health beverage, and the mixing amount of the other raw materials is identical to that of example 4.
Examples 14 to 16
The herbal health beverage of examples 14 to 16 is identical to the preparation method and the raw material type of example 12, except that trigeminal gold is further added to the herbal health beverage raw material, and the specific blending amount is shown in Table 2.
TABLE 2 mixing amount of raw materials (unit: g) of Chinese herbal medicine health beverage of examples 14-16
Raw materials Example 14 Example 15 Example 16
Polygonatum sibiricum 15 15 15
Chinese wolfberry fruit 16.5 16.5 16.5
Flos Chrysanthemi 15 15 15
Dried orange peel 7 7 7
Poria cocos 10 10 10
Hawthorn fruit 8 8 8
Semen cassiae 6 6 6
Mulberry fruit 9 9 9
Buddha's hand 5 5 5
Heavy-petal rose 7 7 7
Dandelion 1 1 1
Gardenia jasminoides ellis 0.5 0.5 0.5
Alcohol extract of kadsura longepedunculata 7 7 7
Carboxylated chitosan 0.2 0.2 0.2
Three-fork gold 5 6 7
Comparative example 1
The herbal health beverage of comparative example 1 is exactly the same as the preparation method of example 1, except that: the Chinese herbal medicine health drink raw material is not added with rhizoma polygonati, and the rest raw materials and the mixing amount are the same as those of the embodiment 1.
Comparative example 2
The herbal health beverage of comparative example 2 is exactly the same as the preparation method of example 1, except that: the Chinese herbal medicine health-care beverage is prepared by the same raw materials and mixing amount as in the embodiment 1 without adding medlar.
Comparative example 3
The herbal health beverage of comparative example 3 is exactly the same as the preparation method of example 1, except that: semen Cassiae is not added in the raw materials of the Chinese herbal medicine health-care beverage, and the other raw materials and the mixing amount are the same as those in the embodiment 1.
Comparative example 4
The herbal health beverage of comparative example 4 is exactly the same as the preparation method of example 1, except that: the raw materials of the Chinese herbal medicine health-care beverage are not added with mulberries, and the other raw materials and the mixing amount are the same as those in the embodiment 1.
Comparative example 5
The herbal health beverage of comparative example 5 is exactly the same as the preparation method of example 1, except that: the traditional Chinese medicine health beverage raw materials are not added with fingered citron, and the other raw materials and the mixing amount are the same as those in the embodiment 1.
Comparative example 6
The herbal health beverage of comparative example 6 is exactly the same as the preparation method of example 1, except that: the dried orange peel is not added in the raw materials of the Chinese herbal medicine health-care beverage, and the other raw materials and the mixing amount are the same as those in the embodiment 1.
Comparative example 7
The herbal health beverage of comparative example 7 is exactly the same as the preparation method of example 1, except that: the raw materials of the Chinese herbal medicine health-care beverage are not added with tribute chrysanthemum, and the other raw materials and the mixing amount are the same as those in the embodiment 1.
Performance detection security: the mice of 115 mice of the white rat species were selected, each of which had a weight of about 18-20g and was equally divided into 23 groups of 5 mice, and were fasted for 6 hours, and the Chinese herbal medicine health drink obtained in examples 1-16 and comparative examples 1-7 was administered by gavage at 10 am, the amount of the gavage administered was 500mg/kg, and the presence or absence of abnormality in the mice was observed 6 hours after gavage and recorded.
Swelling degree: the herbal health beverages obtained in examples 1 to 16 and comparative examples 1 to 7 were then given by gavage at 10 am every day, the amount of gavage was 500mg/kg, 5d was given by gavage, 0.025mL of xylene inflammatory was respectively applied to both sides of the left ear of the mouse after 1h of the last gavage administration, and the swelling degree of the ear of the mouse was calculated after 1h, thereby judging the anti-inflammatory effect of the herbal health beverage of the present application, and specific detection results are shown in Table 3.
Liver protection effect: selecting 115 mice of the white mice, wherein each mouse has a weight of 18-20g, and is divided into 23 groups, 5 groups each, the Chinese herbal medicine health care beverage obtained in the examples 1-16 and the comparative examples 1-7 is administered by intragastric administration at 10 am every day, the administration amount of the intragastric administration is 500mg/kg, after 30min of administration, the intragastric administration is performed for one week, the mice are fasted for 12h after one week, eyeballs are taken out, the mice are sacrificed, the livers are taken out, the taken livers are made into 10% tissue homogenate, the centrifugation is performed at 4000rpm for 20min, the supernatant is divided into the liquid to be tested, and the MDA level and CAT, GST and T-AOC vitality of the liver tissue homogenate are detected.
TABLE 3 Performance test results of different herbal health beverages
Figure BDA0003761444080000131
Firstly, the mice after being observed and lavaged and administered with the Chinese herbal medicine health care beverage for 6 hours do not find any abnormal reaction, do not die, and the skin, the stool, the respiration, the limb activity, the behavior mode and the like do not find any abnormal phenomenon.
In addition, the detection results in Table 3 show that after the Chinese herbal medicine health drink obtained by the application is subjected to gastric lavage, the highest activities of MDA, CAT, GST and T-AOC in the liver tissue homogenate of the mice are respectively 10.69nmol/mL, 73U/mg, 100U/mg and 1.69mg/mL, and the highest activities of glutamic pyruvic transaminase and aspartic transaminase in the blood samples of the mice are respectively 177U/L and 197U/L, so that the Chinese herbal medicine health drink has higher liver nourishing and protecting effects. In addition, the swelling degree of the ears of the mice is 5.7mg at the minimum, and the anti-inflammatory effect is high.
After the Chinese herbal medicine health drink obtained in the example 1 is administrated by stomach infusion, the highest activities of MDA, CAT, GST and T-AOC in the liver tissue homogenate of the mice are respectively 10.25nmol/mL, 50U/mg, 80U/mg and 1.42mg/mL, and the activities of glutamic pyruvic transaminase and aspartic transaminase in the blood samples of the mice are respectively 150U/L and 170U/L; in addition, the ear swelling degree of the mice is 7.0mg, and the liver nourishing and detoxifying effects and the anti-inflammatory effects are high. It may be related to the compatibility of the materials such as fingered citron, cassia seed, tribute chrysanthemum, rhizoma polygonati, medlar and the like added in the Chinese herbal medicine health-care beverage.
After the Chinese herbal medicine health drink obtained in the example 2 is administrated by stomach infusion, the highest activities of MDA, CAT, GST and T-AOC in the liver tissue homogenate of the mice are respectively 10.31nmol/mL, 51U/mg, 82U/mg and 1.44mg/mL, and the activities of glutamic pyruvic transaminase and aspartic transaminase in the blood samples of the mice are respectively 151U/L and 172U/L, which are higher than those in the example 1; in addition, the ear swelling degree of the mice is 6.9mg, which is lower than that of the example 1, and the effects of nourishing liver, detoxifying and diminishing inflammation are higher. The Chinese herbal medicine health-care beverage is characterized in that the rose flowers with the heavy petals, the dandelion and the gardenia are added on the basis of the original raw materials of the Chinese herbal medicine health-care beverage, so that the liver nourishing, detoxifying and anti-inflammatory effects of the Chinese herbal medicine health-care beverage can be further improved, and the Chinese herbal medicine health-care beverage is possibly related to the liver soothing, fire clearing, liver-heat nourishing, blood warming and liver-nourishing effects of the rose flowers with the heavy petals, the dandelion has the liver clearing and eyesight improving effects of the gardenia.
In addition, the heavy-petal rose, dandelion and gardenia are added into the raw materials of the Chinese herbal medicine health-care beverage, the heavy-petal rose has the effects of maintaining beauty and keeping young, and the heavy-petal rose and the flos chrysanthemi are used together to treat irregular menstruation and leucorrhea with reddish white discharge, and the gardenia can supplement water and energy required by a body, has the effects of improving the gas color and resisting oxidation, and is more suitable for female consumers to drink.
After the Chinese herbal medicine health-care beverage obtained in the examples 3-5 is administrated by stomach infusion, the highest activities of MDA, CAT, GST and T-AOC in the liver tissue homogenate of the example 4 are respectively 10.35nmol/mL, 54U/mg, 85U/mg and 1.47mg/mL, and the activities of glutamic pyruvic transaminase and aspartic transaminase in the blood sample of the mouse are respectively 153U/L and 175U/L, which are higher than those in the examples 3 and 5; in addition, the ear swelling degree of the mice is lower than that of the example 3 and the example 5, and the effects of nourishing liver, detoxifying and diminishing inflammation are higher. The results show that the mixing amount of the schisandra chinensis alcohol extract in the raw materials of the Chinese herbal medicine health-care beverage in the embodiment 4 is proper, and the liver nourishing, detoxifying and anti-inflammatory effects of the Chinese herbal medicine health-care beverage can be further improved, and the schisandra chinensis alcohol extract is possibly related to the effects of protecting liver cell membranes, resisting lipid peroxidation, promoting protein biosynthesis, resisting bacteria, diminishing inflammation, liver glycogenesis and the like.
After the Chinese herbal medicine health drink obtained in examples 6-8 is administrated by stomach infusion, the highest activities of MDA, CAT, GST and T-AOC in the liver tissue homogenate of the mice in example 7 are respectively 10.40nmol/mL, 58U/mg, 88U/mg and 1.53mg/mL, and the activities of glutamic pyruvic transaminase and aspartic transaminase in the blood samples of the mice are respectively 157U/L and 180U/L, which are higher than those in examples 6 and 8; in addition, the swelling degree of the ears of the mice is lower than that of the example 6 and the example 8, and the effects of nourishing liver, detoxifying and diminishing inflammation are higher. The method shows that the mixing ratio of the kadsura longepedunculata powder and the ethanol is more proper at 1:9, so that the liver nourishing, detoxifying and anti-inflammatory effects of the Chinese herbal medicine health-care beverage can be further improved, and the method is possibly related to adjusting the mixing ratio of the kadsura longepedunculata powder and the ethanol, and can improve the extraction rate of the kadsura longepedunculata ethanol extract.
After the Chinese herbal medicine health care beverage obtained in the example 7 and the example 9 is administrated by stomach infusion, the highest activities of MDA, CAT, GST and T-AOC in the liver tissue homogenate of the example 9 are respectively 10.42nmol/mL, 61U/mg, 90U/mg and 1.55mg/mL, and the highest activities of glutamic pyruvic transaminase and aspartic transaminase in the blood sample of the mouse are respectively 160U/L and 182U/L, which are higher than those in the example 7; in addition, the swelling degree of the ears of the mice is lower than that of the example 7, and the mice have higher effects of nourishing liver, detoxifying and diminishing inflammation. The method for preparing the schisandra chinensis alcohol extract in the raw materials of the Chinese herbal medicine health-care beverage in the embodiment 9 is shown to be capable of further improving liver nourishing, detoxification and inflammation diminishing of the Chinese herbal medicine health-care beverage by adding petroleum ether into the ethanol mixed solution, and is possibly related to the fact that the petroleum ether can further improve the emulsification effect of kadsura longepedunculata powder in the ethanol mixed solution.
After the herbal health drink obtained in examples 10 to 13 was administered by stomach infusion, the viability of MDA, CAT, GST and T-AOC in the liver homogenate of the mice in example 12 was at most 10.65nmol/mL, 69U/mg, 98U/mg and 1.65mg/mL, respectively; the activity of glutamic pyruvic transaminase and aspartic transaminase in the mouse blood sample is 173U/L and 193U/L respectively, which are higher than those of examples 10-11 and 13; in addition, the ear swelling degree of the mice is 6.0mg, which is higher than that of examples 10-11 and 13, and the effects of nourishing liver, detoxication and anti-inflammation are higher. The results show that in the method for preparing the modified kadsura pepper fruit alcohol extract in the raw materials of the Chinese herbal medicine health-care beverage in example 12, when the mixing ratio of the oil phase solution to the water phase solution is 1:2, the liver nourishing, detoxifying and anti-inflammatory effects of the Chinese herbal medicine health-care beverage can be further improved, and the method is possibly related to adjusting the mixing ratio of the oil phase solution to the water phase solution, and can improve the modification effect of the kadsura pepper fruit alcohol extract.
After the herbal health drink obtained in examples 14 to 16 was administered by stomach infusion, the highest activities of MDA, CAT, GST and T-AOC in the liver homogenate of the mice in example 15 were 10.69nmol/mL, 73U/mg, 100U/mg and 1.69mg/mL, respectively, and the activities of glutamic pyruvic transaminase and aspartic transaminase in the blood samples of the mice were 177U/L and 197U/L, respectively, which were higher than those in examples 14 and 16; in addition, the ear swelling degree of the mice is 5.7mg lower than that of the example 14 and the example 16, and the effects of nourishing liver, detoxifying and diminishing inflammation are higher. The results show that the mixing amount of the trigeminal gold in the raw materials of the Chinese herbal medicine health-care beverage in the embodiment 15 is proper, can further improve the liver nourishing, detoxifying and anti-inflammatory effects of the Chinese herbal medicine health-care beverage, and is possibly related to the good pharmacological activities of anti-inflammatory, anti-tumor, antibacterial, liver protecting and the like of the trigeminal gold, and can further improve the liver protecting and nourishing effects of the beverage.
In addition, comparative example 1 and comparative examples 1 to 7 have found that the addition of Polygonatum sibiricum, lycium barbarum, semen Cassiae, mulberry, fingered citron, pericarpium Citri Tangerinae and flos Chrysanthemi into the raw materials of the Chinese herbal medicine health beverage can improve the liver nourishing and antiinflammatory effects of the Chinese herbal medicine health beverage to different extents.
In conclusion, the Chinese herbal medicine health-care beverage has the effects of maintaining liver damaged cells, clearing heat and detoxicating, and relieving swelling and pain, and has a certain anti-inflammatory effect on acute inflammation. Therefore, the beverage is more suitable for male population suffering from fatigue, human body function decline, human body cell damage, inappetence, drinking and compensation, and sedentary exercise.
The Chinese herbal medicine health-care beverage has the advantages that the heavy-petal rose, dandelion and gardenia are added on the basis of the original raw materials of the Chinese herbal medicine health-care beverage, so that the water and energy of a human body can be supplemented, the gas color can be improved, and a certain antioxidation effect is achieved; in addition, the beverage has good conditioning effect on irregular menstruation and leucorrhea with red and white discharge. Therefore, the Chinese herbal medicine health-care beverage added with the heavy-petal roses, the dandelions and the gardenia is more suitable for female groups with poor qi color, dry skin, lack of water, irregular menstruation and leucorrhea with reddish white discharge.
Selecting 42 healthy male testers, dividing the average into 14 groups, taking 100mL of 56-degree white spirit by 3 people in each group, taking 200mL of purified water by one group of volunteers, taking 200mL of Chinese herbal medicine health-care beverage obtained in examples 1-2, 4, 9, 12 and 15 and comparative examples 1-7 by the other 13 groups of volunteers respectively, and testing by an alcohol tester after 30min, wherein the detection results are shown in Table 4 in detail.
Table 4 trial results of different herbal health beverages
Figure BDA0003761444080000161
As can be seen from the detection results in Table 4, the Chinese herbal medicine health-care beverage obtained by drinking the application can effectively reduce the concentration of ethanol in blood, reduce uncomfortable symptoms after drinking, slightly prevent drunk and treat drunk, inhibit the damage of alcohol to the liver to different degrees, repair damaged liver cells, help the liver detoxify, and realize the liver protection health-care effect of the Chinese herbal medicine health-care beverage.
The present embodiment is merely illustrative of the present application and is not intended to be limiting, and those skilled in the art, after having read the present specification, may make modifications to the present embodiment without creative contribution as required, but is protected by patent laws within the scope of the claims of the present application.

Claims (10)

1. The Chinese herbal medicine health-care beverage is characterized by comprising the following raw materials in parts by weight: 10-20 parts of rhizoma polygonati, 4-6 parts of fingered citron, 8-10 parts of mulberry, 15-20 parts of medlar, 10-20 parts of tribute chrysanthemum, 5-10 parts of dried orange peel, 9-11 parts of poria cocos, 6-10 parts of hawthorn and 5-10 parts of semen cassiae.
2. The herbal health beverage according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 13-18 parts of rhizoma polygonati, 4.5-5.5 parts of fingered citron, 8.5-9.5 parts of mulberry, 18-20 parts of medlar, 13-18 parts of tribute chrysanthemum, 8-10 parts of dried orange peel, 9.5-10.5 parts of poria cocos, 7-9 parts of hawthorn and 7-9 parts of semen cassiae.
3. The herbal health beverage according to claim 1, further comprising the following raw materials in parts by weight: 6-8 parts of rose with heavy petals, 0.5-1.5 parts of dandelion and 0.3-0.7 part of gardenia.
4. The herbal health beverage of claim 1, wherein: the health herbal beverage also comprises the following raw materials in parts by weight: 5-10 parts of kadsura longepedunculata ethanol extract and 0.1-0.3 part of carboxylated chitosan.
5. The herbal health beverage of claim 4, wherein the kadsura longepedunculata extract is obtained by the following steps: drying fructus Schisandrae Sphenantherae at 50-60deg.C for 4-5 hr, and pulverizing to 60-70 mesh to obtain fructus Schisandrae Sphenantherae powder;
adding distilled monoglyceride into 80-90% ethanol solution, wherein the dosage of distilled monoglyceride is 1-3% of the mass of ethanol solution, and stirring to obtain ethanol mixed solution;
the feed liquid ratio is 1: (8-10), adding the kadsura longepedunculata powder into the ethanol mixed solution, carrying out ultrasonic treatment for 10min, centrifuging, collecting supernatant, drying and concentrating to obtain the kadsura longepedunculata ethanol extract.
6. The herbal health beverage of claim 5, wherein: and petroleum ether accounting for 8-12% of the mass of the ethanol solution is also added into the ethanol mixed solution.
7. The herbal health beverage of claim 5, wherein the method for modifying kadsura longepedunculata ethanol extract comprises the following steps:
heating olive oil to 80-90 ℃ according to the mass ratio of kadsura longepedunculata ethanol extract to olive oil of 1: adding kadsura longepedunculata ethanol extract in the ratio of (40-60), stirring and dissolving, and preserving heat to 65-75 ℃ to obtain an oil phase solution;
heating purified water to 65-75 ℃, and mixing soybean lecithin and purified water according to a mass ratio of 1: adding soybean lecithin in the proportion of (35-45), emulsifying for 15-20min, maintaining the temperature to 50-60 ℃, and stirring for 40-50min to obtain aqueous phase solution;
mixing the oil phase solution and the aqueous phase solution according to the mass ratio of 1: mixing the components (2-3), adding tween 20 accounting for 5% of the volume of the olive oil, homogenizing until the particle size of oil drops in water is 40-60nm, and obtaining the modified kadsura longepedunculata alcohol extract.
8. The herbal health beverage according to claim 1, further comprising the following raw materials in parts by weight: 5-7 parts of trigeminal gold.
9. A method for preparing a health beverage of Chinese herbal medicine as claimed in any one of claims 1 to 6 and 8, comprising the following steps:
pulverizing the raw materials of the Chinese herbal medicine health beverage to 40-50 meshes for standby;
mixing purified water and crushed Chinese herbal medicine health-care beverage raw materials according to the total weight of the raw materials and 1% of purified water: mixing (15-25), heating at 90-100deg.C for 15-20min, collecting filtrate, cooling to 20+ -5deg.C, separating and removing impurities, filtering to 280-320 mesh, concentrating, sterilizing at 130-140deg.C, and cooling to obtain concentrated solution;
adding 80-90deg.C purified water to 1000mL, stirring for dissolving, filtering, collecting filtrate, and sterilizing at 130-140deg.C to obtain Chinese herbal medicine health beverage.
10. A method for preparing the Chinese herbal medicine health-care beverage according to claim 7, which is characterized by comprising the following steps:
pulverizing the raw materials of the Chinese herbal medicine health beverage to 40-50 meshes for standby;
mixing purified water and crushed Chinese herbal medicine health-care beverage raw materials according to the total weight of the raw materials and 1% of purified water: mixing (15-25), heating at 80-90deg.C for 15-20min, collecting filtrate, cooling to 20+ -5deg.C, separating and removing impurities, filtering to 280-320 mesh, concentrating, sterilizing at 95-100deg.C, and cooling to obtain concentrated solution;
adding modified kadsura longepedunculata ethanol extract into the concentrated solution, adding purified water of 80-90 ℃ to 1000mL, stirring for dissolving, filtering, collecting filtrate, and sterilizing at high temperature of 95-100 ℃ to obtain the Chinese herbal medicine health beverage.
CN202210871239.0A 2022-07-23 2022-07-23 A health beverage prepared from Chinese herbal materials, and its preparation method Pending CN116172198A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210871239.0A CN116172198A (en) 2022-07-23 2022-07-23 A health beverage prepared from Chinese herbal materials, and its preparation method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210871239.0A CN116172198A (en) 2022-07-23 2022-07-23 A health beverage prepared from Chinese herbal materials, and its preparation method

Publications (1)

Publication Number Publication Date
CN116172198A true CN116172198A (en) 2023-05-30

Family

ID=86431283

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210871239.0A Pending CN116172198A (en) 2022-07-23 2022-07-23 A health beverage prepared from Chinese herbal materials, and its preparation method

Country Status (1)

Country Link
CN (1) CN116172198A (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101574397A (en) * 2009-06-12 2009-11-11 哈尔滨医科大学 WuRenChun self-emulsifying soft capsule preparation and preparation method
CN103859374A (en) * 2012-12-10 2014-06-18 天津红日药业股份有限公司 Formula and preparation method of life cultivation and health preservation food helpful for alleviating visual fatigue
CN105831543A (en) * 2016-03-30 2016-08-10 黄山树德堂食品饮料有限公司 Chrysanthemum health beverage with effects of calming liver and improving eyesight and preparation method thereof
CN108185248A (en) * 2017-12-28 2018-06-22 纽莱福泰姆网络服务（北京）有限公司 It is a kind of relieve the effect of alcohol, protect liver, improve inferior health compound drinks and preparation process
CN110664984A (en) * 2019-11-18 2020-01-10 广东海洋大学 Composition with effects of dispelling effects of alcohol and protecting liver and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101574397A (en) * 2009-06-12 2009-11-11 哈尔滨医科大学 WuRenChun self-emulsifying soft capsule preparation and preparation method
CN103859374A (en) * 2012-12-10 2014-06-18 天津红日药业股份有限公司 Formula and preparation method of life cultivation and health preservation food helpful for alleviating visual fatigue
CN105831543A (en) * 2016-03-30 2016-08-10 黄山树德堂食品饮料有限公司 Chrysanthemum health beverage with effects of calming liver and improving eyesight and preparation method thereof
CN108185248A (en) * 2017-12-28 2018-06-22 纽莱福泰姆网络服务（北京）有限公司 It is a kind of relieve the effect of alcohol, protect liver, improve inferior health compound drinks and preparation process
CN110664984A (en) * 2019-11-18 2020-01-10 广东海洋大学 Composition with effects of dispelling effects of alcohol and protecting liver and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
吴文德;侯小露;辛桂瑜;黄朝伟;陈剑道;: "伤寒头对CCl_4致小鼠急性肝损伤的保护作用及其机理", 基因组学与应用生物学, vol. 29, no. 05, 28 October 2010 (2010-10-28), pages 951 - 956 *
陈碧芸;王东;常秀莲;郭仁红;展鹏远;徐树志;: "乳化剂辅助提取五味子木脂素的研究", 食品科技, vol. 38, no. 09, 20 September 2011 (2011-09-20), pages 247 - 250 *

Similar Documents

Publication Publication Date Title
CN102919450B (en) Cereal leaching solution herbal tea and method for preparing same
CN111956753B (en) Medicinal and edible traditional Chinese medicine composition as well as preparation method and application thereof
CN110354204B (en) Composition with eyesight improving effect and preparation and application methods thereof
CN106174474A (en) A kind of it is applicable to the special dietary seafood that Patients with Cardiovascular/Cerebrovascular Diseases is edible
CN105124605A (en) Health care chewable tablet and preparation method thereof
CN109907221A (en) One kind having antioxidant nutritious various-grain flour and preparation method
CN104208581A (en) Schisandra chinensis health care oral liquid capable of preventing alcoholic liver and preparation method thereof
CN110051815A (en) A kind of auxiliary hyperglycemic food ball and preparation method thereof
CN113186066A (en) SOD wine capable of preserving health and tonifying kidney and preparation method thereof
CN103749827A (en) Preparation method of red ginseng/fig tea
CN106579109A (en) Citrus powder composition capable of neutralizing effect of alcoholic drinks and protecting liver, and preparation method of citrus powder composition
CN104783174A (en) Preparation method of pure natural nutritional, immune and health solid beverage
CN116172198A (en) A health beverage prepared from Chinese herbal materials, and its preparation method
CN104673577B (en) A kind of SOD wine and preparation method
CN107823293A (en) Treat Yao nationality medicine external pulvis of canker sore and preparation method thereof
CN105851336A (en) Dendrobium officinale tea and preparation method thereof
CN109876053A (en) A kind of acne-removing inflammation-diminishing, removing toxic substances of clearing liver prescription and its preparation method
KR20190140738A (en) Vinegar compositions comprising tonic material and manufacturing method thereof
CN114668830B (en) Anti-alcohol and liver-protecting composition and preparation method thereof
CN107034094A (en) A kind of preparation method of channels sootheing and network vessel quickening bee honey health-care wine
CN107090387A (en) A kind of preparation method of invigorating the spleen to clear away damp pathogen bee honey health-care wine
CN106174463A (en) A kind of ultra micro nutrition prescription and preparation processing method preventing and treating hypertensive heart disease based on collaborative absorption
CN106262801A (en) A kind of nutrient formulation nano-particle preventing and treating thrombophlebitis and preparation processing method
CN105851398A (en) Dendrobium officinale health tea and preparation method thereof
CN115944039A (en) Corn stigma and radix puerariae beverage

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination