CN116113830A - 用于测定测量的组合物和方法 - Google Patents

用于测定测量的组合物和方法 Download PDF

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Publication number
CN116113830A
CN116113830A CN202180057701.7A CN202180057701A CN116113830A CN 116113830 A CN116113830 A CN 116113830A CN 202180057701 A CN202180057701 A CN 202180057701A CN 116113830 A CN116113830 A CN 116113830A
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CN
China
Prior art keywords
composition
ecl
tea
surfactant
binding
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Pending
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CN202180057701.7A
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English (en)
Chinese (zh)
Inventor
A·K·塔克-施瓦兹
G·西格尔
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Meso Scale Technologies LLC
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Meso Scale Technologies LLC
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Publication of CN116113830A publication Critical patent/CN116113830A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/30—Electrochemically active labels

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN202180057701.7A 2020-07-01 2021-06-30 用于测定测量的组合物和方法 Pending CN116113830A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063047167P 2020-07-01 2020-07-01
US63/047,167 2020-07-01
PCT/US2021/039835 WO2022006236A1 (en) 2020-07-01 2021-06-30 Compositions and methods for assay measurements

Publications (1)

Publication Number Publication Date
CN116113830A true CN116113830A (zh) 2023-05-12

Family

ID=77317400

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180057701.7A Pending CN116113830A (zh) 2020-07-01 2021-06-30 用于测定测量的组合物和方法

Country Status (9)

Country Link
US (2) US12429427B2 (https=)
EP (1) EP4176263A1 (https=)
JP (1) JP2023532902A (https=)
KR (1) KR20230042471A (https=)
CN (1) CN116113830A (https=)
AU (1) AU2021299536A1 (https=)
CA (1) CA3188484A1 (https=)
IL (1) IL299495A (https=)
WO (1) WO2022006236A1 (https=)

Cited By (1)

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CN116626283A (zh) * 2023-05-15 2023-08-22 广州医科大学附属第一医院（广州呼吸中心） 一种外泌体上kl-6蛋白用于辅助诊断间质性肺部疾病的试剂盒及应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019418498A1 (en) 2019-01-03 2021-07-15 Meso Scale Technologies, Llc Compositions and methods for carrying out assay measurements
WO2026039455A1 (en) 2024-08-13 2026-02-19 Meso Scale Technologies, Llc. Detection of nucleic acids

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Publication number Priority date Publication date Assignee Title
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JP2023532902A (ja) 2023-08-01
CA3188484A1 (en) 2022-01-06
AU2021299536A1 (en) 2023-02-16
IL299495A (en) 2023-02-01
US20220018785A1 (en) 2022-01-20
EP4176263A1 (en) 2023-05-10
KR20230042471A (ko) 2023-03-28
US12429427B2 (en) 2025-09-30
WO2022006236A1 (en) 2022-01-06
US20250354933A1 (en) 2025-11-20

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