CN116113408A - 治疗慢性肾病的方法和药物组合物 - Google Patents
治疗慢性肾病的方法和药物组合物 Download PDFInfo
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- CN116113408A CN116113408A CN202180056137.7A CN202180056137A CN116113408A CN 116113408 A CN116113408 A CN 116113408A CN 202180056137 A CN202180056137 A CN 202180056137A CN 116113408 A CN116113408 A CN 116113408A
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Abstract
本申请涉及一种治疗慢性肾病的方法和药物组合物。本申请的方法和药物组合物涉及多沙唑嗪、普拉克索和美托洛尔(或其可药用的盐)的组合使用，能显著改善慢性肾病，显著降低尿白蛋白排泄率UACR，显著改善肾小球滤过率eGFR，有效延缓肾脏功能减退发展至终末期肾衰。
Description
PCT国内申请，说明书已公开。
Claims (11)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010794864.0A CN114053281A (zh) | 2020-08-10 | 2020-08-10 | 治疗慢性肾病的方法和药物组合物 |
| CN2020107948640 | 2020-08-10 | ||
| PCT/CN2021/106355 WO2022033265A1 (zh) | 2020-08-10 | 2021-07-14 | 治疗慢性肾病的方法和药物组合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116113408A true CN116113408A (zh) | 2023-05-12 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| CN202010794864.0A Pending CN114053281A (zh) | 2020-08-10 | 2020-08-10 | 治疗慢性肾病的方法和药物组合物 |
| CN202180056137.7A Pending CN116113408A (zh) | 2020-08-10 | 2021-07-14 | 治疗慢性肾病的方法和药物组合物 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010794864.0A Pending CN114053281A (zh) | 2020-08-10 | 2020-08-10 | 治疗慢性肾病的方法和药物组合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230181542A1 (zh) |
| EP (1) | EP4193997A1 (zh) |
| JP (1) | JP2023537418A (zh) |
| KR (1) | KR20230050406A (zh) |
| CN (2) | CN114053281A (zh) |
| AU (1) | AU2021326180A1 (zh) |
| CA (1) | CA3189106A1 (zh) |
| WO (1) | WO2022033265A1 (zh) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114053281A (zh) * | 2020-08-10 | 2022-02-18 | 成都文鼎科技发展有限公司 | 治疗慢性肾病的方法和药物组合物 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7348140B1 (en) * | 2001-07-25 | 2008-03-25 | Acadia Pharmaceuticals, Inc. | Clinical indications for genotyping polymorphic variants of G-protein coupled receptors |
| CN101237870A (zh) * | 2005-06-03 | 2008-08-06 | 田边三菱制药株式会社 | 伴随的药物试剂及其用途 |
| CN101965184A (zh) * | 2008-01-11 | 2011-02-02 | 里亚塔医药公司 | 合成三萜类化合物及用以治病之方法 |
| CN114053281A (zh) * | 2020-08-10 | 2022-02-18 | 成都文鼎科技发展有限公司 | 治疗慢性肾病的方法和药物组合物 |
| CN115364101A (zh) * | 2021-05-21 | 2022-11-22 | 成都文鼎科技发展有限公司 | 治疗糖尿病周围神经病变的方法和药物组合物 |
-
2020
- 2020-08-10 CN CN202010794864.0A patent/CN114053281A/zh active Pending
-
2021
- 2021-07-14 KR KR1020237008408A patent/KR20230050406A/ko unknown
- 2021-07-14 JP JP2023509760A patent/JP2023537418A/ja active Pending
- 2021-07-14 CA CA3189106A patent/CA3189106A1/en active Pending
- 2021-07-14 WO PCT/CN2021/106355 patent/WO2022033265A1/zh active Application Filing
- 2021-07-14 CN CN202180056137.7A patent/CN116113408A/zh active Pending
- 2021-07-14 EP EP21855318.8A patent/EP4193997A1/en active Pending
- 2021-07-14 AU AU2021326180A patent/AU2021326180A1/en active Pending
-
2023
- 2023-02-09 US US18/107,835 patent/US20230181542A1/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7348140B1 (en) * | 2001-07-25 | 2008-03-25 | Acadia Pharmaceuticals, Inc. | Clinical indications for genotyping polymorphic variants of G-protein coupled receptors |
| CN101237870A (zh) * | 2005-06-03 | 2008-08-06 | 田边三菱制药株式会社 | 伴随的药物试剂及其用途 |
| CN101965184A (zh) * | 2008-01-11 | 2011-02-02 | 里亚塔医药公司 | 合成三萜类化合物及用以治病之方法 |
| CN114053281A (zh) * | 2020-08-10 | 2022-02-18 | 成都文鼎科技发展有限公司 | 治疗慢性肾病的方法和药物组合物 |
| CN115364101A (zh) * | 2021-05-21 | 2022-11-22 | 成都文鼎科技发展有限公司 | 治疗糖尿病周围神经病变的方法和药物组合物 |
Non-Patent Citations (1)
| Title |
|---|
| MARRICK L.KUKIN 等: "Combined Alpha-Beta Blockade (Doxazosin Plus Metoprolol) Compared With Beta Blockade Alone in Chronic Congestive Heart Failure", THE AMERICAN JOURNAL OF CARDIOLOGY, vol. 77, 31 March 1996 (1996-03-31), pages 486 - 491, XP055901300, DOI: 10.1016/S0002-9149(97)89342-3 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023537418A (ja) | 2023-08-31 |
| CN114053281A (zh) | 2022-02-18 |
| EP4193997A1 (en) | 2023-06-14 |
| WO2022033265A1 (zh) | 2022-02-17 |
| AU2021326180A1 (en) | 2023-03-16 |
| US20230181542A1 (en) | 2023-06-15 |
| CA3189106A1 (en) | 2022-02-17 |
| KR20230050406A (ko) | 2023-04-14 |
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