CN116077398A - Plant allergy relieving agent for skin care and preparation method thereof - Google Patents
Plant allergy relieving agent for skin care and preparation method thereof Download PDFInfo
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- CN116077398A CN116077398A CN202310259043.0A CN202310259043A CN116077398A CN 116077398 A CN116077398 A CN 116077398A CN 202310259043 A CN202310259043 A CN 202310259043A CN 116077398 A CN116077398 A CN 116077398A
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- 206010020751 Hypersensitivity Diseases 0.000 title claims abstract description 54
- 208000026935 allergic disease Diseases 0.000 title claims abstract description 54
- 230000007815 allergy Effects 0.000 title claims abstract description 42
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- 239000000284 extract Substances 0.000 claims abstract description 74
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- 239000011347 resin Substances 0.000 claims abstract description 57
- 229920005989 resin Polymers 0.000 claims abstract description 57
- 238000001179 sorption measurement Methods 0.000 claims abstract description 57
- 239000000419 plant extract Substances 0.000 claims abstract description 9
- 238000002156 mixing Methods 0.000 claims abstract description 6
- 230000000844 anti-bacterial effect Effects 0.000 claims abstract description 4
- 244000183278 Nephelium litchi Species 0.000 claims description 86
- 239000003795 chemical substances by application Substances 0.000 claims description 50
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 35
- 239000000243 solution Substances 0.000 claims description 17
- 238000005406 washing Methods 0.000 claims description 17
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 16
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 15
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 15
- 238000002791 soaking Methods 0.000 claims description 14
- 239000011259 mixed solution Substances 0.000 claims description 13
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 12
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- 239000000706 filtrate Substances 0.000 claims description 6
- 230000007935 neutral effect Effects 0.000 claims description 6
- 241000283690 Bos taurus Species 0.000 claims description 5
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- 238000005119 centrifugation Methods 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 238000007710 freezing Methods 0.000 claims description 5
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- 239000003112 inhibitor Substances 0.000 claims description 4
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- 238000001816 cooling Methods 0.000 claims description 3
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 claims description 3
- 239000001649 glycyrrhiza glabra l. absolute Substances 0.000 claims description 3
- 229940051810 licorice root extract Drugs 0.000 claims description 3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/81—Preparation or application process involves irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/84—Products or compounds obtained by lyophilisation, freeze-drying
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the technical field of skin care preparations, in particular to a plant allergy relieving agent for skin care and a preparation method thereof. A preparation method of a plant allergy relieving agent for skin care comprises the following steps: s1, preparing litchi peel extract; s2, purifying litchi peel extract by using adsorption resin; s3, dissolving and mixing the plant extracts to prepare a plant sensitivity-relieving agent; s4, performing antibacterial treatment on the plant allergy relieving agent. According to the invention, the litchi pericarp extract is mixed with other plant extracts with the allergy-relieving effect, so that the prepared plant allergy-relieving agent has better allergy-relieving effect, and the skin barrier enhancing effect is improved.
Description
Technical Field
The invention relates to the technical field of skin care preparations, in particular to a plant allergy relieving agent for skin care and a preparation method thereof.
Background
Skin allergy is easily caused when skin is subjected to various stimuli, and the received stimuli include chemicals, pollen, foods, medicines, dust particles in air, cosmetics and the like, and are often manifested as swelling, dryness, itching, peeling, other inflammation and other abnormal phenomena when skin is allergic. When people are allergic to skin, the skin care and allergy relieving agent is smeared on the allergic place, and the skin care and allergy relieving agent is expected to relieve the bad symptoms of the skin. The existing plant allergy-relieving agent has single allergy-relieving component, so that the allergy-relieving agent has poor effect and takes effect slowly.
The information disclosed in this background section is only for enhancement of understanding of the general background of the invention and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person of ordinary skill in the art.
Disclosure of Invention
In view of the shortcomings of the prior art, the invention aims to provide a plant allergy relieving agent for skin care and a preparation method thereof.
A preparation method of a plant allergy relieving agent for skin care comprises the following steps:
s1: preparation of litchi peel extract
Drying and primarily crushing litchi peel, adding the primarily crushed litchi peel into an ultra-micro jet mill for crushing, performing microwave extraction on the ultra-micro jet crushed litchi peel, and finally performing suction filtration and centrifugation to obtain clear litchi peel extract;
s2: purification of litchi pericarp extract by adsorption resin
Pretreating macroporous adsorption resin, soaking and washing the macroporous adsorption resin with absolute ethyl alcohol, adding the macroporous adsorption resin into litchi peel extract, sealing the litchi peel extract, placing the sealed litchi peel extract on a constant-temperature freezing shaking machine, adsorbing the litchi peel extract by using the macroporous adsorption resin, and desorbing the macroporous adsorption resin to obtain the litchi peel extract;
s3: dissolving and mixing plant extracts to prepare plant allergy relieving agent
Adding the litchi pericarp extract, the radix sophorae flavescentis extract, the radix scutellariae extract, the centella asiatica extract, the purslane extract and the liquorice extract into a mixed solution of butanediol, glycerol and 1, 2-hexanediol to obtain a plant allergy relieving agent;
s4: antibacterial treatment of plant allergy relieving agent
Adding p-hydroxyacetophenone into the plant sensitivity-relieving agent, and stirring by using a stirrer in the step S2 until the p-hydroxyacetophenone is completely dissolved in the plant sensitivity-relieving agent, so as to obtain a finished product of the plant sensitivity-relieving agent.
Further, the step S1 of preparing litchi peel extract specifically comprises the following steps:
s1.1: low temperature drying and primary pulverizing
Taking a sufficient amount of litchi peel, sending the litchi peel into a vacuum freeze dryer, vacuumizing and cooling to-40 to-35 ℃ for low-temperature drying for 15-30 hours, and placing the litchi peel subjected to low-temperature drying into a pulverizer for preliminary pulverization;
s1.2: superfine powder jet milling
Weighing the primarily crushed litchi peel, placing the litchi peel in an ultrafine jet mill, crushing for 5-30 min, filtering and screening the litchi peel by a 500-800 mesh screen, and crushing litchi peel powder to 500-800 mesh;
s1.3: microwave extraction
Adding the crushed litchi peel powder into 50-70% ethanol water solution, wherein the feed-liquid ratio is 1: 15-20 g/mL, carrying out 450-600W microwave extraction on the solution for 20-30 min;
s1.4: filtering and centrifuging the extractive solution
Adding the litchi pericarp extract into a vacuum suction filter, pouring out filtrate to obtain solid filter residues, putting the filtrate into a centrifuge, centrifuging at 3500-4000 rpm for 10-15 min, and collecting the supernatant after centrifugation.
Further, the step S2 of purifying the litchi rind extract liquid by using the adsorption resin specifically comprises the following steps:
s2.1: pretreating macroporous adsorption resin, putting the macroporous adsorption resin and absolute ethyl alcohol into a sealing tank, sealing and soaking for 20-24 hours, taking out, washing the macroporous adsorption resin with new absolute ethyl alcohol until the macroporous adsorption resin is not white and turbid in an ethanol soaking environment, washing the macroporous adsorption resin with distilled water until the macroporous adsorption resin is free of ethanol smell, soaking the macroporous adsorption resin with 3-8% hydrochloric acid solution for 12-15 hours, washing with distilled water until the macroporous adsorption resin is neutral, soaking with 2-5% NaOH solution for 10-12 hours, and washing with distilled water until the macroporous adsorption resin is neutral;
s2.2: placing macroporous adsorption resin and litchi peel extract in a sealed tank, immersing the litchi peel extract in the macroporous adsorption resin, placing the sealed tank on a constant-temperature freezing shaking table, and adsorbing for 12-18 h at 15-30 ℃ and 80-120 r/min;
s2.3: washing macroporous adsorption resin for 1-2 times with distilled water and wiping off surface moisture, then placing the macroporous adsorption resin and ethanol solution with the concentration of 30-50% in a conical flask, sealing, placing on a constant temperature cold shaking table, and resolving for 24-30 h under the conditions of 25-30 ℃ and 120-150 r/min to obtain the litchi peel extract.
Further, the step S3 of dissolving and mixing the plant extracts to prepare the plant desensitizer specifically comprises the following steps:
adding 2-3 parts of litchi pericarp extract, 1-2 parts of radix sophorae flavescentis extract, 1-2 parts of radix scutellariae extract, 2-3 parts of centella asiatica extract, 1-2 parts of purslane extract and 0.5-1 part of licorice root extract into a mixed solution of butanediol, glycerol and 1, 2-hexanediol, adding into a stirrer, stirring, and slowly stirring for 5-10 min until the plant allergy relieving extract is uniformly mixed in the mixed solution of butanediol, glycerol and 1, 2-hexanediol, thereby obtaining the plant allergy relieving agent.
Further, in the step S3, the ratio of butanediol, glycerol to 1, 2-hexanediol in the mixed solution of butanediol, glycerol and 1, 2-hexanediol is 1:1 to 3:0.1 to 0.6.
A plant allergy relieving agent for skin care is prepared by the preparation method of the plant allergy relieving agent for skin care.
Further, the plant allergy-relieving agent for skin care can be used for one of facial masks, skin cream, facial cleanser, skin care essence, skin lotion, sun cream and skin care gel.
The beneficial effects are that:
1. according to the invention, the litchi pericarp extract is mixed with other plant extracts with the allergy-relieving effect, so that the prepared plant allergy-relieving agent has better allergy-relieving effect, and the skin barrier enhancing effect is improved.
2. The invention adds macroporous adsorption resin into the litchi peel extract, so that the macroporous adsorption resin fully adsorbs the litchi peel extract in the litchi peel extract, and then the litchi peel extract is obtained by desorption, thus the purity of the litchi peel extract is more precise, and the impurities are reduced.
Drawings
FIG. 1 is a flow chart of a method for preparing a plant allergy inhibitor for skin care according to an embodiment of the present invention.
Fig. 2 is a graph of the sensory evaluation results of volunteers employed in the examples of the present invention.
Fig. 3 is a graph of the test results of the volunteer TEWL value employed in the example of the present invention.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
A preparation method of a plant allergy relieving agent for skin care, see figure 1, comprises the following steps:
s1: preparation of litchi peel extract
Firstly, taking a sufficient amount of litchi peel, sending the litchi peel into a vacuum freeze dryer, vacuumizing and cooling to-40 to-35 ℃ for low-temperature drying for 15-30 hours, and placing the litchi peel subjected to low-temperature drying into a pulverizer for preliminary pulverization; secondly, weighing the primarily crushed litchi peel, placing the litchi peel in an ultrafine jet mill, crushing for 5-30 min, filtering and screening the litchi peel by a 500-800 mesh screen, and crushing litchi peel powder to 500-800 meshes; adding 70% ethanol water solution into the crushed litchi peel powder, wherein the feed liquid ratio is 1: 15-20 g/mL, carrying out 450-600W microwave extraction on the solution for 20-30 min; and finally, adding the litchi pericarp extract into a vacuum suction filter, pouring out filtrate to obtain solid filter residues, putting the filtrate into a centrifugal machine, centrifuging at 3500-4000 rpm for 10-15 min, and collecting the supernatant after centrifugation.
S2: purification of litchi pericarp extract by adsorption resin
Firstly, pretreating macroporous adsorption resin, putting the macroporous adsorption resin and absolute ethyl alcohol into a sealing tank, sealing and soaking for 24 hours, taking out, washing the macroporous adsorption resin with new absolute ethyl alcohol until the macroporous adsorption resin is free from white turbidity in an ethanol soaking environment, washing the macroporous adsorption resin with distilled water until the macroporous adsorption resin is free from ethanol smell, soaking the macroporous adsorption resin with 5% hydrochloric acid solution for 12 hours, washing with distilled water to be neutral, soaking with 2% NaOH solution for 12 hours, and washing with distilled water to be neutral; placing macroporous adsorption resin and litchi peel extract in a sealed tank, immersing the litchi peel extract in the macroporous adsorption resin, placing the sealed tank on a constant-temperature freezing shaking table, and adsorbing for 12-18 h at 15-30 ℃ and 80-120 r/min; finally, washing the macroporous adsorption resin for 1-2 times by using distilled water and wiping off surface moisture, then placing the macroporous adsorption resin and an ethanol solution with the concentration of 30-50% in a conical flask, sealing, placing the conical flask on a constant-temperature cold shaking table, and analyzing for 24-30 h under the conditions of 25-30 ℃ and 120-150 r/min to obtain the litchi peel extract.
The invention adds macroporous adsorption resin into the litchi peel extract, so that the macroporous adsorption resin fully adsorbs the litchi peel extract in the litchi peel extract, and then the litchi peel extract is obtained by desorption, thus the purity of the litchi peel extract is more precise, and the impurities are reduced.
S3: dissolving and mixing plant extracts to prepare plant allergy relieving agent
Adding 2 parts of litchi pericarp extract, 1 part of radix sophorae flavescentis extract, 1 part of radix scutellariae extract, 2 parts of centella asiatica extract, 1 part of purslane extract and 0.5 part of licorice root extract into a mixed solution of butanediol, glycerol and 1, 2-hexanediol, adding into a stirrer, stirring, and slowly stirring for 10min until the plant allergy extract is uniformly mixed in the mixed solution of butanediol, glycerol and 1, 2-hexanediol to obtain a plant allergy relieving agent, wherein the ratio of butanediol, glycerol and 1, 2-hexanediol in the mixed solution of butanediol and glycerol is 1:2:0.1.
s4: antibacterial treatment of plant allergy relieving agent
Adding p-hydroxyacetophenone into the plant sensitivity-relieving agent, and stirring by using a stirrer in the step S2 until the p-hydroxyacetophenone is completely dissolved in the plant sensitivity-relieving agent, so as to obtain a finished product of the plant sensitivity-relieving agent.
According to the invention, the litchi pericarp extract is mixed with other plant extracts with the allergy relieving effect, so that the prepared plant allergy relieving agent has better allergy relieving effect, and the effect of enhancing the skin barrier function is improved.
Example 2
24 volunteers with certain acnes on the face were selected for testing, and the volunteers were equally divided into three groups. The plant sensitivity-relieving agent prepared in the example 1 is smeared on the facial skin after the first group of volunteers clean the face in the morning and evening every day, and 5 to 10 drops of the plant sensitivity-relieving agent are smeared each time; the second group of volunteers apply plant allergy relieving agent without adding litchi peel extract to facial skin after cleaning the face in the morning and evening every day, and each time the plant allergy relieving agent is applied for 5-10 drops; the third group of volunteers is used as a control group, and after cleansing the face in the morning and evening, the mixed solution of butanediol, glycerol and 1, 2-hexanediol is smeared on the facial skin, and 5 to 10 drops of the mixed solution are smeared each time; wherein the ratio of butanediol, glycerol and 1, 2-hexanediol is 1:2:0.1. three groups of volunteers were subjected to the following test after 7 days of continuous use.
Sensory evaluation
Three groups of volunteers were subjected to sensory evaluation of the plant-based allergy inhibitor used according to the sense of use, evaluated from Shu Mindu and mildness. The above effects were evaluated using 100 grades, each group taking an average of the evaluation values, the specific evaluation values being shown in fig. 2. As can be seen from fig. 2, subjective evaluation based on volunteers showed a greater improvement in softness and mildness for the plant-soothing agent containing the litchi rind extract than for the plant-soothing agent without the litchi rind extract.
Evaluation of allergy-relaxing Effect
The test results of TEWL values at cheek sites measured with tewattmeter (tm) 300 before use and after 2 weeks of continued use for volunteers are shown in fig. 3.
An increase in TEWL value means an increase in skin moisture emission and a decrease in TEWL value indicates that the barrier is repaired, and thus the decrease in TEWL value of the skin reflects the soothing effect of the plant soothing agent. The average TEWL value of the first group of volunteers continuously coated for 7 days is reduced by 11.64%, the average TEWL value of the second group of volunteers continuously coated for 14 days is reduced by 21.61%, the average TEWL value of the second group of volunteers continuously coated for 7 days is reduced by 8.82%, and the average TEWL value of the second group of volunteers continuously coated for 14 days is reduced by 15.88%, so that the plant allergy relieving agent containing the litchi peel extract can be obviously improved in the effect of repairing the plant allergy relieving agent compared with the plant allergy relieving agent without the litchi peel extract.
The above embodiments are merely illustrative of the principles of the present invention and its effectiveness, and are not intended to limit the invention. Modifications and variations may be made to the above-described embodiments by those skilled in the art without departing from the spirit and scope of the invention. Accordingly, it is intended that all equivalent modifications and variations of the invention be covered by the claims, which are within the ordinary skill of the art, be within the spirit and scope of the present disclosure.
Claims (7)
1. The preparation method of the plant allergy relieving agent for skin care is characterized by comprising the following steps of:
s1: preparation of litchi peel extract
Drying and primarily crushing litchi peel, adding the primarily crushed litchi peel into an ultra-micro jet mill for crushing, performing microwave extraction on the ultra-micro jet crushed litchi peel, and finally performing suction filtration and centrifugation to obtain clear litchi peel extract;
s2: purification of litchi pericarp extract by adsorption resin
Pretreating macroporous adsorption resin, soaking and washing the macroporous adsorption resin with absolute ethyl alcohol, adding the macroporous adsorption resin into litchi peel extract, sealing the litchi peel extract, placing the sealed litchi peel extract on a constant-temperature freezing shaking machine, adsorbing the litchi peel extract by using the macroporous adsorption resin, and desorbing the macroporous adsorption resin to obtain the litchi peel extract;
s3: dissolving and mixing plant extracts to prepare plant allergy relieving agent
Adding the litchi pericarp extract, the radix sophorae flavescentis extract, the radix scutellariae extract, the centella asiatica extract, the purslane extract and the liquorice extract into a mixed solution of butanediol, glycerol and 1, 2-hexanediol to obtain a plant allergy relieving agent;
s4: antibacterial treatment of plant allergy relieving agent
Adding p-hydroxyacetophenone into the plant sensitivity-relieving agent, and stirring by using a stirrer in the step S2 until the p-hydroxyacetophenone is completely dissolved in the plant sensitivity-relieving agent, so as to obtain a finished product of the plant sensitivity-relieving agent.
2. The method for preparing the plant allergy relieving agent for skin care according to claim 1, wherein the step S1 of preparing the litchi rind extract specifically comprises the following steps:
s1.1: low temperature drying and primary pulverizing
Taking a sufficient amount of litchi peel, sending the litchi peel into a vacuum freeze dryer, vacuumizing and cooling to-40 to-35 ℃ for low-temperature drying for 15-30 hours, and placing the litchi peel subjected to low-temperature drying into a pulverizer for preliminary pulverization;
s1.2: superfine jet milling
Weighing the primarily crushed litchi peel, placing the litchi peel in an ultrafine jet mill, crushing for 5-30 min, filtering and screening the litchi peel by a 500-800 mesh screen, and crushing litchi peel powder to 500-800 mesh;
s1.3: microwave extraction
Adding the crushed litchi peel powder into 50-70% ethanol water solution, wherein the feed-liquid ratio is 1: 15-20 g/mL, carrying out 450-600W microwave extraction on the solution for 20-30 min;
s1.4: filtering and centrifuging the extractive solution
Adding the litchi pericarp extract into a vacuum suction filter, pouring out filtrate to obtain solid filter residues, putting the filtrate into a centrifuge, centrifuging at 3500-4000 rpm for 10-15 min, and collecting the supernatant after centrifugation.
3. The method for preparing the plant allergy relieving agent for skin care according to claim 2, wherein the step S2 of purifying the litchi rind extract by adsorption resin specifically comprises the following steps:
s2.1: pretreating macroporous adsorption resin, putting the macroporous adsorption resin and absolute ethyl alcohol into a sealing tank, sealing and soaking for 20-24 hours, taking out, washing the macroporous adsorption resin with new absolute ethyl alcohol until the macroporous adsorption resin is not white and turbid in an ethanol soaking environment, washing the macroporous adsorption resin with distilled water until the macroporous adsorption resin is free of ethanol smell, soaking the macroporous adsorption resin with 3-8% hydrochloric acid solution for 12-15 hours, washing with distilled water until the macroporous adsorption resin is neutral, soaking with 2-5% NaOH solution for 10-12 hours, and washing with distilled water until the macroporous adsorption resin is neutral;
s2.2: placing macroporous adsorption resin and litchi peel extract in a sealed tank, immersing the litchi peel extract in the macroporous adsorption resin, placing the sealed tank on a constant temperature freezing shaking table, and heating at 15-30deg.C
Adsorbing for 12-18 h under the condition of 80-120 r/min;
s2.3: washing macroporous adsorption resin for 1-2 times with distilled water and wiping off surface moisture, then placing the macroporous adsorption resin and ethanol solution with the concentration of 30-50% in a conical flask, sealing, placing on a constant temperature cold shaking table, and resolving for 24-30 h under the conditions of 25-30 ℃ and 120-150 r/min to obtain the litchi peel extract.
4. The method for preparing a plant desensitizing agent for skin care according to claim 3, wherein said step S3 of dissolving and mixing plant extracts to prepare the plant desensitizing agent comprises the steps of:
adding 2-3 parts of litchi pericarp extract, 1-2 parts of radix sophorae flavescentis extract, 1-2 parts of radix scutellariae extract, 2-3 parts of centella asiatica extract, 1-2 parts of purslane extract and 0.5-1 part of licorice root extract into a mixed solution of butanediol, glycerol and 1, 2-hexanediol, adding into a stirrer, stirring, and slowly stirring for 5-10 min until the plant allergy relieving extract is uniformly mixed in the mixed solution of butanediol, glycerol and 1, 2-hexanediol, thereby obtaining the plant allergy relieving agent.
5. The method for preparing a plant allergy-relieving agent for skin care according to claim 4, wherein the ratio of butanediol, glycerol and 1, 2-hexanediol in the mixed solution of butanediol, glycerol and 1, 2-hexanediol in the step S3 is 1:1 to 3:0.1 to 0.6.
6. A plant allergy inhibitor for skin care, characterized in that it is prepared by a process for preparing a plant allergy inhibitor for skin care according to any one of the preceding claims 1 to 5.
7. The plant skin care soothing agent according to claim 6, wherein the plant skin care soothing agent is used in one of a mask, a cream, a cleanser, a skin essence, a lotion, a sunscreen, and a gel.
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