CN116033901A - 用于治疗眼睛障碍的化合物和方法 - Google Patents

用于治疗眼睛障碍的化合物和方法 Download PDF

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Publication number
CN116033901A
CN116033901A CN202180056862.4A CN202180056862A CN116033901A CN 116033901 A CN116033901 A CN 116033901A CN 202180056862 A CN202180056862 A CN 202180056862A CN 116033901 A CN116033901 A CN 116033901A
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CN
China
Prior art keywords
compound
pharmaceutically acceptable
acceptable salt
subject
amount
Prior art date
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Pending
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CN202180056862.4A
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English (en)
Chinese (zh)
Inventor
D·凯利
M·帕帕迪米特里奥
C·博恩斯
E·丹尼尔斯
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OccuRx Pty Ltd
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OccuRx Pty Ltd
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Publication date
Priority claimed from AU2020901858A external-priority patent/AU2020901858A0/en
Application filed by OccuRx Pty Ltd filed Critical OccuRx Pty Ltd
Publication of CN116033901A publication Critical patent/CN116033901A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN202180056862.4A 2020-06-05 2021-06-03 用于治疗眼睛障碍的化合物和方法 Pending CN116033901A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2020901858A AU2020901858A0 (en) 2020-06-05 Compounds and Methods for the Treatment of Eye Disorders
AU2020901856 2020-06-05
AU2020901858 2020-06-05
AU2020901856A AU2020901856A0 (en) 2020-06-05 Compounds and Methods for the Treatment of Eye Disorders
PCT/US2021/035749 WO2021247900A1 (en) 2020-06-05 2021-06-03 Compounds and methods for the treatment of eye disorders

Publications (1)

Publication Number Publication Date
CN116033901A true CN116033901A (zh) 2023-04-28

Family

ID=78829970

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180056862.4A Pending CN116033901A (zh) 2020-06-05 2021-06-03 用于治疗眼睛障碍的化合物和方法

Country Status (11)

Country Link
US (1) US20230270703A1 (https=)
EP (1) EP4161527A4 (https=)
JP (1) JP2023529845A (https=)
KR (1) KR20230024331A (https=)
CN (1) CN116033901A (https=)
AU (1) AU2021284380A1 (https=)
BR (1) BR112022024728A2 (https=)
CA (1) CA3185849A1 (https=)
IL (1) IL298733A (https=)
MX (1) MX2022015327A (https=)
WO (2) WO2021247900A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112023018314A2 (pt) * 2021-03-17 2023-10-31 Occurx Pty Ltd Compostos para o tratamento de distúrbios e sais e polimorfos dos mesmos

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6339814A (ja) * 1986-08-01 1988-02-20 Teisan Seiyaku Kk トラニラストの経口用持続性製剤
KR19990082523A (ko) * 1996-02-15 1999-11-25 간자와 무츠와 혈관생성 억제제
JPH09278653A (ja) * 1996-04-05 1997-10-28 Santen Pharmaceut Co Ltd 網膜疾患治療剤
CN1252718A (zh) * 1997-04-18 2000-05-10 橘生药品工业株式会社 预防或治疗与视网膜色素上皮细胞过度增殖相关的疾病的药剂
ATE526041T1 (de) * 2001-12-11 2011-10-15 Fibrogen Inc Verfahren zur hemmung okularer vorgänge
NZ592039A (en) * 2003-08-27 2013-03-28 Ophthotech Corp Combination therapy for the treatment of ocular neovascular disorders
US8168584B2 (en) * 2005-10-08 2012-05-01 Potentia Pharmaceuticals, Inc. Methods of treating age-related macular degeneration by compstatin and analogs thereof
ES2830024T3 (es) * 2007-10-19 2021-06-02 Novartis Ag Composiciones y métodos para el tratamiento del edema macular
JP2011006406A (ja) * 2009-05-29 2011-01-13 Santen Pharmaceut Co Ltd トラニラストを含有する網膜疾患の予防または治療剤
NZ609144A (en) * 2010-11-24 2014-08-29 Occurx Pty Ltd Methods of treating eye diseases associated with inflammation and vascular proliferation
US10780070B2 (en) * 2013-10-18 2020-09-22 The Schepens Eye Research Institute, Inc. Alpha-aminoadipate for treatment of vision loss and restoring sight

Also Published As

Publication number Publication date
AU2021284380A1 (en) 2023-01-19
EP4161527A4 (en) 2024-06-26
US20230270703A1 (en) 2023-08-31
KR20230024331A (ko) 2023-02-20
JP2023529845A (ja) 2023-07-12
IL298733A (en) 2023-02-01
MX2022015327A (es) 2023-02-22
WO2021247900A1 (en) 2021-12-09
CA3185849A1 (en) 2021-12-09
BR112022024728A2 (pt) 2023-03-07
WO2021247901A1 (en) 2021-12-09
EP4161527A1 (en) 2023-04-12

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