CN116018128A - 清凉感组合物 - Google Patents

清凉感组合物 Download PDF

Info

Publication number
CN116018128A
CN116018128A CN202080104248.6A CN202080104248A CN116018128A CN 116018128 A CN116018128 A CN 116018128A CN 202080104248 A CN202080104248 A CN 202080104248A CN 116018128 A CN116018128 A CN 116018128A
Authority
CN
China
Prior art keywords
imidazol
isopropyl
tolyl
methyl
flavor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080104248.6A
Other languages
English (en)
Chinese (zh)
Inventor
佐治德一
T·巴斯隆梅
N·科塞托阿玛尼诺
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Givaudan SA
Original Assignee
Givaudan SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan SA filed Critical Givaudan SA
Publication of CN116018128A publication Critical patent/CN116018128A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/06Chewing gum characterised by the composition containing organic or inorganic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20Synthetic spices, flavouring agents or condiments
    • A23L27/202Aliphatic compounds
    • A23L27/2024Aliphatic compounds having oxygen as the only hetero atom
    • A23L27/2028Carboxy compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20Synthetic spices, flavouring agents or condiments
    • A23L27/205Heterocyclic compounds
    • A23L27/2054Heterocyclic compounds having nitrogen as the only hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/24Thermal properties
    • A61K2800/244Endothermic; Cooling; Cooling sensation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Seasonings (AREA)
CN202080104248.6A 2020-08-05 2020-12-16 清凉感组合物 Pending CN116018128A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2012170.3 2020-08-05
GBGB2012170.3A GB202012170D0 (en) 2020-08-05 2020-08-05 Organic compounds
PCT/EP2020/086367 WO2022028726A1 (en) 2020-08-05 2020-12-16 Cooling sensation compositions

Publications (1)

Publication Number Publication Date
CN116018128A true CN116018128A (zh) 2023-04-25

Family

ID=72425143

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202080104248.6A Pending CN116018128A (zh) 2020-08-05 2020-12-16 清凉感组合物
CN202180057437.7A Pending CN116096347A (zh) 2020-08-05 2021-07-28 清凉感组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202180057437.7A Pending CN116096347A (zh) 2020-08-05 2021-07-28 清凉感组合物

Country Status (8)

Country Link
US (2) US20230310293A1 (https=)
EP (2) EP4192422B1 (https=)
JP (2) JP2023536934A (https=)
CN (2) CN116018128A (https=)
ES (1) ES3037685T3 (https=)
GB (1) GB202012170D0 (https=)
PL (1) PL4192423T3 (https=)
WO (2) WO2022028726A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202012170D0 (en) * 2020-08-05 2020-09-16 Givaudan Sa Organic compounds
GB202102676D0 (en) * 2021-02-25 2021-04-14 Givaudan Sa Compositions
GB202103207D0 (en) * 2021-03-08 2021-04-21 Givaudan Sa Organic compounds
GB202315636D0 (en) * 2023-10-12 2023-11-29 Givaudan Sa Composition
WO2025202256A1 (en) * 2024-03-28 2025-10-02 Firmenich Sa Cooling composition

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4919043A (https=) * 1972-04-18 1974-02-20
JPH07506868A (ja) * 1992-05-18 1995-07-27 ザ、プロクター、エンド、ギャンブル、カンパニー 冷却剤組成物
US20050013846A1 (en) * 2001-11-23 2005-01-20 Pelan Barbara Margaretha Water continuous food product with cooling flavour
DE102008015428A1 (de) * 2008-03-20 2009-09-24 Beiersdorf Ag Kühlende Zubereitungen für den humanen Haut- und/oder Schleimhautkontakt mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexancarboxamid
CN102036716A (zh) * 2008-05-22 2011-04-27 奇华顿股份有限公司 清凉组合物

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190643A (en) * 1971-02-04 1980-02-26 Wilkinson Sword Limited Compositions having a physiological cooling effect
GB1422998A (en) * 1973-03-22 1976-01-28 Wilkinson Sword Ltd Cyclohexanecarboxamides having a physiological cooling effect and compositions containing them
US3988433A (en) 1973-08-10 1976-10-26 The Procter & Gamble Company Oral compositions for preventing or removing stains from teeth
US4083955A (en) 1975-04-02 1978-04-11 The Procter & Gamble Company Processes and compositions for remineralization of dental enamel
US4528180A (en) 1983-03-01 1985-07-09 Schaeffer Hans A Dental preparation, article and method for storage and delivery thereof
US4849213A (en) 1983-03-01 1989-07-18 Schaeffer Hans A Dental preparation, article and method for storage and delivery therof
US5198220A (en) 1989-11-17 1993-03-30 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5281410A (en) 1991-10-23 1994-01-25 The Proctor & Gamble Company Methods of reducing plaque and gingivitis with reduced staining
US5145666A (en) 1991-10-23 1992-09-08 The Proctor & Gamble Co. Methods of reducing plaque and gingivitis with reduced staining
US5213790A (en) 1991-10-23 1993-05-25 The Procter & Gamble Co. Methods of reducing plaque and gingivitis with reduced staining
US5242910A (en) 1992-10-13 1993-09-07 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US7858800B2 (en) * 2004-06-30 2010-12-28 Banyu Pharmaceutical Co., Ltd. Biaryl derivatives
HUP0500920A2 (en) * 2005-10-05 2007-07-30 Richter Gedeon Nyrt Oxadiazole derivatives, process for their preparation and their use
US7803963B2 (en) * 2007-10-15 2010-09-28 Millennium Specialty Chemicals, Inc. Physiological coolants based on lactoyl esters of menthyl lactate
DE102008015424A1 (de) * 2008-03-20 2009-09-24 Beiersdorf Ag Kühlende kosmetische oder dermatologische Zubereitungen mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridyn-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5- methylcyclohexancarboxamid mit Menthoxypropandiol
AU2009318056B2 (en) 2008-11-20 2014-07-24 The Procter & Gamble Company Personal care compositions providing enhanced cooling sensation
GB201103103D0 (en) * 2011-02-23 2011-04-06 Givaudan Sa Organic compounds
WO2014054635A1 (ja) * 2012-10-02 2014-04-10 大日本住友製薬株式会社 イミダゾール誘導体
WO2014090293A1 (de) * 2012-12-12 2014-06-19 Symrise Ag Zubereitungen
US20170087199A1 (en) * 2016-02-10 2017-03-30 Senomyx, Inc. Compositions for delivering a cooling sensation
KR102493173B1 (ko) * 2017-01-10 2023-01-27 다카사고 고료 고교 가부시키가이샤 메틸멘톨 유도체 및 그것을 함유하는 냉감제 조성물
JP7222969B2 (ja) 2017-07-14 2023-02-15 フイルメニツヒ ソシエテ アノニム 冷感調合物
US12528801B2 (en) * 2019-10-17 2026-01-20 Givaudan Sa Substituted azacyles as TRPM8 modulators
GB202012170D0 (en) * 2020-08-05 2020-09-16 Givaudan Sa Organic compounds

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4919043A (https=) * 1972-04-18 1974-02-20
JPH07506868A (ja) * 1992-05-18 1995-07-27 ザ、プロクター、エンド、ギャンブル、カンパニー 冷却剤組成物
US20050013846A1 (en) * 2001-11-23 2005-01-20 Pelan Barbara Margaretha Water continuous food product with cooling flavour
DE102008015428A1 (de) * 2008-03-20 2009-09-24 Beiersdorf Ag Kühlende Zubereitungen für den humanen Haut- und/oder Schleimhautkontakt mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexancarboxamid
CN102036716A (zh) * 2008-05-22 2011-04-27 奇华顿股份有限公司 清凉组合物

Also Published As

Publication number Publication date
JP2023536934A (ja) 2023-08-30
US20230310293A1 (en) 2023-10-05
PL4192423T3 (pl) 2025-09-22
US20230277427A1 (en) 2023-09-07
WO2022028976A1 (en) 2022-02-10
GB202012170D0 (en) 2020-09-16
WO2022028726A1 (en) 2022-02-10
EP4192422A1 (en) 2023-06-14
EP4192422B1 (en) 2025-06-11
EP4192423B1 (en) 2025-05-21
CN116096347A (zh) 2023-05-09
EP4192423A1 (en) 2023-06-14
JP7835730B2 (ja) 2026-03-25
ES3037685T3 (en) 2025-10-06
JP2023536932A (ja) 2023-08-30

Similar Documents

Publication Publication Date Title
CN116018128A (zh) 清凉感组合物
CN101257949B (zh) 清凉化合物
CN100466915C (zh) 薄荷基半酸酯衍生物及其制备方法,以及它在消费品中清凉/提神功效的应用
US10299999B2 (en) Flavour composition comprising menthol and menthane carboxamides
JP2010513657A (ja) N−置換−p−メンタン−3−カルボキサミドおよびこれらの使用
EP1682641B1 (en) Flavor ingredients for cooling preparations
US20240139087A1 (en) Organic compounds as trpm8 activators
EP4065566B1 (en) Trpm8 modulators
US20240197604A1 (en) Compounds with cooling sensation properties
KR20120018339A (ko) 생리학적 효과를 갖는 화합물
WO2026052684A1 (en) Flavour compositions
US20250066320A1 (en) Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same
WO2014009374A1 (en) 3-substituted para-methane derivatives
WO2014009416A1 (en) 3-substituted para-menthane derivatives

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20230425