CN115955969A - 用于口服治疗白血病的组合物和方法 - Google Patents
用于口服治疗白血病的组合物和方法 Download PDFInfo
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- CN115955969A CN115955969A CN202180038959.2A CN202180038959A CN115955969A CN 115955969 A CN115955969 A CN 115955969A CN 202180038959 A CN202180038959 A CN 202180038959A CN 115955969 A CN115955969 A CN 115955969A
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A61K31/33—Heterocyclic compounds
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- A61K31/365—Lactones
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| PCT/US2021/027702 WO2022220841A1 (en) | 2021-04-16 | 2021-04-16 | Composition and method for oral treatment of leukemia |
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| US7648695B2 (en) * | 1998-08-06 | 2010-01-19 | Provectus Pharmatech, Inc. | Medicaments for chemotherapeutic treatment of disease |
| KR20070022308A (ko) * | 2004-05-10 | 2007-02-26 | 로버트 에프 호프만 | 암 치료용 약제학적 조성물 |
| RU2636046C2 (ru) * | 2009-01-12 | 2017-11-17 | Сайтомкс Терапьютикс, Инк | Композиции модифицированных антител, способы их получения и применения |
| US8765725B2 (en) * | 2012-05-08 | 2014-07-01 | Aciex Therapeutics, Inc. | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof |
| WO2018047917A1 (ja) * | 2016-09-09 | 2018-03-15 | 国立大学法人 東京大学 | Ｈｍｇタンパク質と抗ｃｄ４抗体又は免疫チェックポイント制御剤との組み合わせによる相乗的抗腫瘍効果 |
| IL269986B2 (en) * | 2017-04-12 | 2024-06-01 | Aura Biosciences Inc | Integrated and focused treatment |
| CN110621316B (zh) * | 2017-04-21 | 2024-01-26 | Epizyme股份有限公司 | 用ehmt2抑制剂进行的组合疗法 |
| EP3773548B1 (en) * | 2018-05-16 | 2023-08-09 | Provectus Pharmatech, Inc. | In vitro and xenograft anti-tumor activity of a halogenated-xanthene against refractory pediatric solid tumors |
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- 2021-04-16 MX MX2022012945A patent/MX2022012945A/es unknown
- 2021-04-16 JP JP2022562946A patent/JP2023529262A/ja active Pending
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- 2021-04-16 WO PCT/US2021/027702 patent/WO2022220841A1/en unknown
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- 2021-04-16 EP EP21935450.3A patent/EP4117668A4/en active Pending
- 2021-04-16 KR KR1020227039851A patent/KR20230171854A/ko active Search and Examination
Also Published As
| Publication number | Publication date |
|---|---|
| KR20230171854A (ko) | 2023-12-21 |
| EP4117668A4 (en) | 2023-12-06 |
| CA3175637A1 (en) | 2022-10-20 |
| WO2022220841A1 (en) | 2022-10-20 |
| JP2023529262A (ja) | 2023-07-10 |
| AU2021440597A1 (en) | 2022-11-10 |
| MX2022012945A (es) | 2023-03-16 |
| EP4117668A1 (en) | 2023-01-18 |
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