CN115869375A - Traditional Chinese medicine composition for clearing heat and dispelling wind as well as preparation method and application thereof - Google Patents

Traditional Chinese medicine composition for clearing heat and dispelling wind as well as preparation method and application thereof Download PDF

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CN115869375A
CN115869375A CN202310057666.XA CN202310057666A CN115869375A CN 115869375 A CN115869375 A CN 115869375A CN 202310057666 A CN202310057666 A CN 202310057666A CN 115869375 A CN115869375 A CN 115869375A
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chinese medicine
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CN115869375B (en
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张忠德
杨荣源
丁邦晗
郭建文
奚小土
刘云涛
郑丹文
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Guangdong Hospital of Traditional Chinese Medicine
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Guangdong Hospital of Traditional Chinese Medicine
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Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for clearing heat and dispelling wind, which comprises the following main active ingredients in parts by mass: 10-15 parts of mulberry leaf, 10-15 parts of divaricate saposhnikovia root, 15-20 parts of figwort root, 15-20 parts of weeping forsythia, 15-20 parts of reed rhizome, 10-15 parts of platycodon root, 15-20 parts of radix pseudostellariae and 5-10 parts of liquorice. The heat-clearing wind-dispelling traditional Chinese medicine composition provided by the invention has the effects of dispelling wind, clearing heat, detoxifying and relieving cough, and can be effectively used for treating symptoms such as fever, headache, sore throat, cough, yellow phlegm, thirst, red tongue with yellow coating, floating and rapid pulse and the like after novel coronavirus infection. In addition, the traditional Chinese medicine composition for clearing heat and dispelling wind provided by the invention has the effects of clearing wind, clearing heat, detoxifying and relieving cough, and taking the lung and spleen into consideration, so that the effects of eliminating pathogenic factors without damaging vital qi and strengthening body resistance to assist in eliminating pathogenic factors are achieved, and the symptoms of abdominal distension, diarrhea and the like caused by the fact that the spleen and the stomach are damaged to influence the stomach tolerance of patients due to the weakness of the spleen and the stomach in the south ridge region are avoided.

Description

Traditional Chinese medicine composition for clearing heat and dispelling wind as well as preparation method and application thereof
Technical Field
The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for clearing heat and dispelling wind and application thereof.
Background
In the process of preventing and treating the novel coronavirus, the traditional Chinese medicine has remarkable advantages. In the existing novel diagnosis and treatment scheme for coronavirus infection, the prescription for treating the novel coronavirus infection patients mostly focuses on treating the novel coronavirus infection with syndromes of epidemic toxin exterior syndrome, cold-dampness stagnation in lung syndrome and damp-heat accumulation in lung syndrome, and the prescription for treating the novel coronavirus infection patients with syndromes of fever, headache, sore throat, cough, yellow phlegm, thirst, red tongue with yellow fur, floating and rapid pulse and the like which are manifested by symptoms of wind-heat epidemic toxin attacking lung is still lacked at present. Particularly, patients infected by the novel coronavirus in the south of five Ridges are affected by geographical and climatic characteristics of thin ground and easily released yang qi, spring Xia Duoyu, heavy mist and hot and humid ground, and patients in the south of five Ridges mostly have constitutional characteristics of excessive stomach deficiency and unconsolidated primordial qi, are frequently applied with cold and cool products for clearing heat and detoxifying and the like, are more easily damaged in the spleen and stomach, have no lung defense due to spleen qi deficiency, and are difficult to cure exogenous diseases and even difficult to take effect sometimes.
Therefore, there is still a need for a novel Chinese medicinal composition for treating coronavirus infection with wind-heat epidemic toxin attacking lung.
Disclosure of Invention
The first objective of the present invention is to provide a Chinese medicine composition for clearing heat and dispelling wind to solve at least one of the above technical problems.
The second objective of the present invention is to provide a preparation method of the Chinese medicinal composition, so as to solve at least one of the above technical problems.
The third objective of the present invention is to provide an application of the Chinese medicinal composition to solve at least one of the above technical problems.
According to one aspect of the invention, the invention provides a traditional Chinese medicine composition for clearing heat and dispelling wind, which comprises the following main active ingredients in parts by mass: 10-15 parts of mulberry leaf, 10-15 parts of divaricate saposhnikovia root, 15-20 parts of figwort root, 15-20 parts of weeping forsythia capsule, 15-20 parts of reed rhizome, 10-15 parts of platycodon root, 15-20 parts of heterophylly falsestarwort root and 5-10 parts of liquoric root.
In the formula, the mulberry leaves are sweet, cold and moist in quality, can slightly clear and disperse wind heat on the exterior, can clear lung heat by bitter cold, and can moisten lung dryness to relieve cough by Gan Hanliang; fructus forsythiae is cool in nature and bitter in taste, and can clear and float upwards lightly, and can treat heat in upper energizer to remove toxicity, and the fructus forsythiae are monarch drugs which can disperse wind-heat and clear heat in upper energizer. The divaricate saposhnikovia root is slightly warm but not dry, and can help the weeping forsythia to strengthen and disperse wind-heat; the figwort is salty, cold and moist in nature, can moisten various liquid, and has the functions of nourishing yin, reducing pathogenic fire, detoxifying and relieving sore throat; the reed rhizome is sweet and cold in taste, not greasy in nature, and capable of promoting the production of body fluid without loving evil, not only can clear lung heat and eliminate phlegm to stop cough, but also can clear stomach heat and promote the production of body fluid to quench thirst, and the three medicines are used as ministerial medicines, so that the three medicines can help monarch medicines to dispel wind and clear heat, and also can detoxify, relieve sore throat, promote the production of body fluid to stop cough. Radix platycodonis and radix pseudostellariae are used as adjuvant drugs, the radix platycodonis strengthens the effects of clearing lung and relieving sore throat, and the radix pseudostellariae tonifies spleen and lung, and benefits qi and promotes the production of body fluid. Licorice root, radix Glycyrrhizae coordinates the effects of the other drugs in the recipe. The medicines are combined together and play the roles of dispelling wind, clearing heat, detoxifying and relieving cough.
The traditional Chinese medicine composition for clearing heat and dispelling wind provided by the invention can effectively relieve symptoms such as fever, headache, sore throat, cough, yellow phlegm, thirst, red tongue with yellow fur, floating and rapid pulse and the like of a patient who is infected with a novel coronavirus and is proved to be infected with wind-heat epidemic toxin and lung attacking syndrome, has obvious curative effects on the patient with severe sore throat and dry mouth and throat, is not provided with a product with severe cold in the formula, can threaten to hurt the yang qi of the spleen and the stomach, is added with radix pseudostellariae and liquorice to tonify the spleen and the lung, benefit qi and promote the production of body fluid, and simultaneously dispels pathogenic factors and strengthens the body resistance, and does not cause the symptoms such as stomach damage to the spleen and the stomach to influence the stomach tolerance of the patient, and abdominal distension and diarrhea. The traditional Chinese medicine composition for clearing heat and dispelling wind provided by the invention can be used for preparing a medicine for treating novel coronavirus infection, and particularly can be used for preparing a medicine for treating a novel coronavirus infection patient with a syndrome of wind-cold epidemic toxin attacking lung.
The traditional Chinese medicine composition for clearing heat and dispelling wind provided by the invention closely combines the physical characteristics of people in south of five Ridges, gives consideration to the lung and spleen on the basis of dispelling wind, clearing heat, detoxifying and relieving cough, eliminates pathogenic factors without damaging vital qi, strengthens the body resistance to eliminate pathogenic factors with assistance, and better accords with the geographical and climatic characteristics and the disease onset characteristics of the south of five Ridges.
In some embodiments, the heat-clearing wind-dispelling traditional Chinese medicine composition comprises the following main active ingredients in parts by mass: 10 parts of mulberry leaf, 10 parts of divaricate saposhnikovia root, 15 parts of figwort root, 15 parts of weeping forsythia capsule, 15 parts of reed rhizome, 10 parts of platycodon root, 20 parts of radix pseudostellariae and 5 parts of liquorice.
The traditional Chinese medicine composition for clearing heat and dispelling wind is mainly used for treating symptoms such as fever, headache, sore throat, cough, yellow phlegm, thirst, red tongue with yellow fur, floating and rapid pulse and the like after the novel coronavirus infection; in the practical application process, the dosage and the type of the raw material medicinal materials can be clinically added or subtracted according to the specific symptoms and the severity of the symptoms of a patient, and 10-20 parts of radix bupleuri and 5-15 parts of radix scutellariae can be added if the headache and the body pain are obvious; for patients with obvious pharyngalgia, 10-20 parts of rhizoma Belamcandae and 5-10 parts of radix scrophulariae can be added; for cough, add Ephedra sinica Stapf 3-10 parts and Fritillaria thunbergii 10-20 parts.
The raw materials of the method are as follows:
mulberry leaf: is dried leaf of Morus alba L. Of Morus of Moraceae. Sweet, bitter and cold in nature; it enters lung and liver meridians.
Wind prevention: is root of Saposhnikovia divaricata (Turcz.) Schischk. Of Saposhnikovia of Umbelliferae. Pungent and sweet in flavor and slightly warm in nature; it enters bladder, lung, spleen and liver meridians.
Figwort root: is dried root of Scrophularia ningpoensis Hemsl. And Scrophularia borensis S.buergeriana Miq [ S.oldhami Oliv ] of Scrophularia of Scrophulariaceae. Sweet, bitter, salty and slightly cold in nature; it enters lung, stomach and kidney meridians.
Fructus forsythiae: is dried fruit of Vahl, forsytniausspensa (Thunb.) of Forsythia of Oleaceae. Bitter taste and slightly cold nature; it enters lung, heart and small intestine meridians.
Reed rhizome: is a fresh or dried rhizome of Phragmitis communis Trin, a plant of the genus Phragmitis, family Gramineae. Sweet taste and cold nature; it enters lung and stomach meridians.
Balloon flower: is dried root of A.DC. of Platycodon grandiflorum Platycodon grandiflorum (Jacq.) of Campanulaceae. Bitter and pungent taste, mild in nature; it enters lung meridian.
Radix pseudostellariae: is root tuber of Pseudostellaria heterophylla (Miq) pax ex pax et hoffm. Sweet and bitter taste, mild in nature; it enters spleen and lung meridians.
Licorice root: is dried root and rhizome of Glycyrrhiza uralensis Fisch, glycyrrhiza inflata Bat, or Glycyrrhiza glabra L of Glycyrrhiza of Leguminosae. Sweet in flavor and mild in nature; it enters heart, lung, spleen and stomach meridians.
Bupleurum root: is dried root of Bupleurum chinense DC or Bupleurum scorzonerifolium Willd. Pungent and bitter in flavor and slightly cold in nature; it enters liver, gallbladder and lung meridians.
Scutellaria baicalensis: is dried root of Scutellaria baicalensis Georgi of Scutellaria of Labiatae. Bitter taste and cold nature; it enters lung, gallbladder, spleen, large intestine and small intestine meridians.
Shooting: is dried rhizome of Belamcanda chinensis (L.) DC. Of Belamcanda chinensis (L.) of Belamcanda of Iridaceae. Bitter taste and cold nature; it enters lung meridian.
Roasting ephedra: is prepared from herbaceous stems of Ephedra sinica Stapf, ephedra intermedia Schrenk et C.A.Mey, or Ephedra equisetifolia equisetum Bge of Ephedra of Ephedraceae by processing with honey. The ephedra herb is pungent and slightly bitter in taste and warm in nature; it enters lung and bladder meridians, and stir-baked with honey can alleviate pungent and dispersing properties and make the properties warm and moist.
Thunberg fritillary bulb: is bulb of Fritillaria thunbergii Miq. Bitter taste and cold nature; it enters lung and heart meridians.
In some embodiments, the dosage form of the Chinese medicinal composition can be decoction, tablets, capsules, granules, oral liquid or powder.
In some embodiments, pharmaceutically acceptable excipients, such as sustained release agents, excipients, fillers, binders, humectants, disintegrants, absorption enhancers, adsorptive carriers, surfactants, lubricants, and the like, are also included.
When the traditional Chinese medicine composition is a decoction, the preparation method comprises the following steps:
mixing the raw material medicines according to a ratio, adding 8-12 times of water by weight, soaking for 20-40 minutes, decocting for 1-2 hours, filtering, repeatedly decocting the filter residue for 1-2 times, and combining the filtrates to obtain the traditional Chinese medicine composition. The filtrate can be packaged after being cooled, thereby being convenient for carrying and distribution.
When the powder is used, the preparation method can comprise the following steps:
respectively crushing or chopping the raw materials, respectively sieving the crushed or chopped raw materials with 10-mesh and 50-mesh sieves, continuously crushing or chopping coarse particles which cannot pass through the 10-mesh sieve, taking powder between the 10-mesh and 50-mesh sieves, uniformly mixing the raw material powder according to a ratio, filling into a packaging bag, and sealing.
When the preparation is tablets, capsules, granules and other dosage forms, the preparation method can comprise the following steps:
mixing the raw materials at a certain ratio, making into extract (each 1g of extract is equivalent to 2-5g of raw materials), adding adjuvants, and making into corresponding dosage forms according to conventional preparation process of Chinese medicine.
Detailed Description
The present invention will be described in further detail with reference to specific examples. Unless otherwise specified, the raw materials and reagents used in the present invention are commercially available.
Example 1
The traditional Chinese medicine decoction for clearing heat and dispelling wind of the embodiment is prepared from the following raw material medicines in a dosage (about 200 mL) per dose: 10g of mulberry leaf, 10g of divaricate saposhnikovia root, 15g of figwort root, 15g of weeping forsythia, 15g of reed rhizome, 10g of platycodon root, 20g of radix pseudostellariae and 5g of liquorice.
The preparation method comprises the following steps:
mixing the raw material medicines according to a ratio, adding 10 times of water to soak for 30 minutes, then heating to boil, keeping slight boiling for 1 hour, and filtering to obtain a first decoction and dregs; taking the medicine residues obtained after the first decoction, adding water which is 8 times of the total mass of the raw material medicines by weight, heating to boil, keeping slightly boiling for 1 hour, and separating to obtain a second decoction and the medicine residues; mixing the first decoction and the second decoction.
In order to verify the treatment effect of the traditional Chinese medicine composition, the decoction of the heat-clearing wind-dispelling prescription prepared in the embodiment 1 of the invention is used as a test medicine for carrying out clinical research, and the research process and the result are as follows:
1. correlation criteria
1.1 diagnostic criteria
1.1.1 Western medical disease diagnosis
With reference to "diagnosis and treatment for novel coronavirus infection" (trial tenth edition), there were epidemiological histories and clinical manifestations, consistent with the etiological evidence (positive detection of nucleic acid or positive detection of antigen in new coronavirus).
The disease typing refers to the diagnosis and treatment scheme for novel coronavirus infection (trial tenth edition), which is classified into light type, ordinary type, heavy type and dangerous type.
1.1.2 Chinese medicine syndrome diagnostic standard
Syndrome of external wind-heat: fever, or high fever, no aversion to cold, headache, muscular soreness, dry throat and sore throat, dry mouth and bitter taste, cough, red tongue with yellow coating, and superficial and rapid pulse.
1.2 inclusion criteria
(1) Those positive for neocorona nucleic acid or antigen detection;
(2) The type classification standard referred to "diagnosis and treatment plan for coronavirus infection" (trial tenth edition) is light.
(3) Age 18-65 years (border values included);
(4) Signing the informed consent.
Exclusion criteria:
(1) In combination with acute onset of severe underlying or chronic disease, such as acute heart failure.
(2) A pregnant, lactating, or lactating female subject;
(3) The medicine has the diseases of bronchopneumonia, chronic lung abscess, chronic cough for more than 8 weeks, chronic pharyngolaryngitis accompanied with cough and the like, which affect the duration of symptoms.
3. Case withdrawal and detachment
Case withdrawal and loss refer to cases in which patients are reluctant to continue clinical trials or fail to complete the entire course of treatment as prescribed during the study after they are enrolled.
Treatment of withdrawal and shedding cases: the investigator should contact the subject by way of family visit, telephone, letter, etc. and record the last treatment time to complete the evaluation project. And understand the reason for its withdrawal, as faithfully recorded in the case report form. The observation data of all the cases of withdrawal and abscission are reserved.
2. The source of the cases is: a novel coronavirus infection mild case diagnosed and treated by a traditional Chinese medicine fever clinic in Guangdong province within the research period.
3. Intervention and grouping:
all patients who are brought into the heat-clearing wind-dispelling prescription group take 200mL of the heat-clearing wind-dispelling prescription decoction prepared in the example 1 every day, 1 dose every day, 2 times in the morning and evening, 100mL of the decoction is taken every time, and the median treatment course is 5 days.
After all patients are put into the hospital, diagnosis and treatment are carried out according to the diagnosis and treatment scheme for pneumonia infected by novel coronavirus (trial ninth edition), so that basic treatment of the patients is guaranteed, but antiviral treatment is not carried out.
4. The statistical method comprises the following steps:
and (3) carrying out normality test on the measurement data, wherein the normality test is in accordance with the description of mean +/-standard deviation for normality, the use median and quartile description in accordance with normal distribution, the curative effect is successively compared, the data of the normal distribution is subjected to pairing t test, and the data of the abnormal distribution is subjected to non-parametric test. The counting data is checked by chi-square.
5. Test results
1. Baseline analysis
Baseline data for patients are shown in table 1:
TABLE 1 Baseline data sheet for patients
Figure BDA0004060763440000051
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Figure BDA0004060763440000061
As shown in table 1, the distribution of the gender of the two groups is balanced, and compared with the control group which does not take the decoction of the heat-clearing wind-dispelling prescription, the patients of the heat-clearing wind-dispelling prescription group are older; the time from onset to follow-up is obviously shorter for the heat-clearing and wind-dispelling formula group than for the control group, and more combined medicines are used for the control group, especially for the medicines for relieving cough and reducing sputum.
2. The symptoms of the patients at onset are shown in Table 2
TABLE 2 onset of symptoms in patients
Symptoms (n,%) Control group (n = 47) Heat clearing and wind dispelling square set (n = 204)
Generate heat 38(80.8) 182(89.2)
Cough with asthma 44(93.6) 156(76.4)
Nasal obstruction or discharge 33(70.2) 131(64.2)
Sore throat 36(76.5) 126(61.7)
Muscular pain 29(61.7) 73(35.7)
Headache (headache) 24(51.0) 68(33.3)
Tiredness 36(76.5) 58(28.4)
Aversion to cold or shivering 27(57.4) 48(23.5)
Abnormal taste 14(29.7) 43(21.0)
Abnormal sense of smell 11(23.4) 27(13.2)
Shortness of breath or dyspnea 23(48.9) 17(8.33)
Diarrhea (diarrhea) 13(27.6) 21(10.2)
Nausea 13(27.6) 11(5.39)
Vomiting 5(10.6) 8(3.92)
As shown in table 2, the first four symptoms of the heat-clearing wind-dispelling prescription are fever, cough, nasal obstruction/discharge and sore throat; the symptom with the highest proportion of the heat-clearing wind-dispelling prescription is fever, the proportion is 89.2 percent, and the fever and the second symptom cough (76.4 percent) have symptom dominance.
3. Symptom disappearance table after patient taking medicine
TABLE 3 symptom disappearance assessment Scale for patients
Figure BDA0004060763440000062
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Figure BDA0004060763440000071
As shown in table 3, compared with the control group, the heat-clearing and wind-dispelling prescription has better effect on fever, cold-fearing/chill and has statistical significance for the difference; the effect of relief against breathlessness/dyspnea was also better than the control group, but the difference had not reached a statistically significant level.
4. Time table for disappearance of symptoms after patient takes medicine
TABLE 4 evaluation chart of symptom disappearance time of patient
Time to disappearance of symptoms (Tian, IQR) Control group (n = 47) Heat clearing and wind dispelling square set (n = 204) P value
Generate heat 4(3-5) 2(2-4) 0.01
Nasal obstruction or discharge 5.5(3.25-8.5) 5(3-6) 0.502
Sore throat 4.5(3.75-7.75) 4(3.75-5) 0.502
Shortness of breath or dyspnea 6(6-6) 3(2.25-6) 0.468
Cough with asthma 4(2.5-10.5) 5(3-7) 0.826
Fatigue 7.5(3.75-10.5) 4(3-5) 0.092
Muscular pain 5(2-6.5) 3(2-4) 0.161
Headache (headache) 4.5(2.75-5.25) 3(2-4) 0.208
Aversion to cold or shivering 5(1-6) 2(2-3) 0.415
Nausea - 1(1-2.5) -
Vomiting 3(3-3) 2.5(1.25-7.5) 0.623
Diarrhea (diarrhea) 3(2.25-7.5) 3(2-4) 0.838
Abnormal sense of smell - 4(3-5.25) -
Abnormal taste - 3(2-5) -
As shown in table 4, the heat-clearing and wind-dispelling group significantly reduced the fever time of the patients (2 days vs 4 days, P = 0.01) and also reduced the fatigue time of the patients (4 days vs7.5 days, P = 0.092) compared to the control group, but the difference did not reach a statistically significant level.
5. Residual symptom table after patient treatment
TABLE 5 residual symptoms after treatment of patients
Symptoms (n,%) Control group (n = 47) Heat clearing and wind dispelling square set (n = 204)
Cough with a symptom of the lung 37(78.7) 127(62.2)
Nasal obstruction or discharge 23(48.9) 69(33.8)
Sore throat 11(23.4) 49(24.0)
Fatigue 23(48.9) 30(14.7)
Abnormal taste 16(34.0) 19(9.3)
Headache (headache) 7(14.8) 11(5.4)
Abnormal sense of smell 13(27.6) 12(5.9)
Shortness of breath or dyspnea 15(31.9) 6(2.9)
Muscular pain 11(23.4) 11(5.4)
Diarrhea (diarrhea) 3(6.4) 9(4.4)
Generate heat 6(12.7) 8(3.9)
Aversion to cold or shivering 15(31.9) 5(2.5)
Nausea 5(10.6) 3(1.5)
Vomiting 0(0) 1(0.5)
As shown in Table 5, the main residual symptoms after the treatment of the heat-clearing wind-dispelling formula group are cough, the control group accounts for 78.7%, the heat-clearing wind-dispelling formula group accounts for 62.2%, and except for cough, the symptoms except nasal obstruction/running nose, sore throat and fatigue after the treatment of each group are below 10%.
6. And (4) conclusion:
(1) After the heat-clearing and wind-dispelling prescription is taken for 5 days, the symptoms of the patients are obviously improved, and the difference has statistical significance.
(2) The heat-clearing wind-dispelling prescription can remarkably relieve symptoms of cough and the like of a patient and remarkably shorten disappearance time of various symptoms.
In the practical application process, the dosage and the type of the raw material medicinal materials can be subjected to clinical trial addition and subtraction according to the specific symptoms and the severity of the symptoms of a patient, such as: on the basis of example 1, if the headache and body pain are obvious, 15g of radix bupleuri and 10g of radix scutellariae can be added; for marked pharyngalgia, rhizoma Belamcandae 15g and radix scrophulariae 10g can be added; for cough, add Huang Ma (herba Ephedrae preparata) 5g and Zhe Bei mu (Bulbus Fritillariae Thunbergii) 15g.
What has been described above are merely some embodiments of the present invention. It will be apparent to those skilled in the art that various changes and modifications can be made therein without departing from the spirit and scope of the invention.

Claims (9)

1. The traditional Chinese medicine composition for clearing heat and dispelling wind is characterized by comprising the following main active ingredients in parts by mass: 10-15 parts of mulberry leaf, 10-15 parts of divaricate saposhnikovia root, 15-20 parts of figwort root, 15-20 parts of weeping forsythia, 15-20 parts of reed rhizome, 10-15 parts of platycodon root, 15-20 parts of radix pseudostellariae and 5-10 parts of liquorice.
2. The traditional Chinese medicine composition for clearing heat and dispelling wind as claimed in claim 1, wherein the main active ingredients comprise, in parts by mass: 10 parts of mulberry leaf, 10 parts of divaricate saposhnikovia root, 15 parts of figwort root, 15 parts of weeping forsythia capsule, 15 parts of reed rhizome, 10 parts of platycodon root, 20 parts of radix pseudostellariae and 5 parts of liquorice.
3. The heat-clearing wind-dispelling traditional Chinese medicine composition according to claim 1 or 2, characterized in that the main active ingredients further comprise one or more selected from 10-20 parts of radix bupleuri, 5-15 parts of radix scutellariae, 10-20 parts of blackberry lily, 5-10 parts of radix scrophulariae, 3-10 parts of mix-fried ephedra herb and 10-20 parts of thunberg fritillary bulb in parts by mass.
4. The traditional Chinese medicine composition for clearing heat and dispelling wind according to claim 3, wherein the dosage form of the traditional Chinese medicine composition is decoction, tablets, capsules, granules, oral liquid or powder.
5. The traditional Chinese medicine composition for clearing heat and dispelling wind according to claim 4, characterized by further comprising medically acceptable auxiliary materials.
6. The heat-clearing wind-dispelling traditional Chinese medicine composition according to claim 5, wherein the medically acceptable auxiliary material is at least one selected from a sustained-release agent, an excipient, a filler, a binder, a wetting agent, a disintegrating agent, an absorption enhancer, an adsorption carrier, a surfactant and a lubricant.
7. The preparation method of the traditional Chinese medicine composition for clearing heat and dispelling wind as claimed in claim 4, wherein when the traditional Chinese medicine composition is a decoction, the preparation method comprises the following steps:
mixing the raw material medicines according to a ratio, adding 8-12 times of water by weight, soaking for 20-40 minutes, decocting for 1-2 hours, filtering, repeatedly decocting the filter residue for 1-2 times, and combining the filtrates to obtain the traditional Chinese medicine composition.
8. Use of the heat-clearing wind-dispelling Chinese medicinal composition according to any one of claims 1 to 6 in the preparation of a medicament for treating a novel coronavirus infection.
9. The use according to claim 8, wherein the novel coronavirus infection is a novel coronavirus infection with a syndrome of wind-heat epidemic virus attacking the lung.
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