CN115812725B - Insecticidal composition containing fluxazole amide and application thereof - Google Patents
Insecticidal composition containing fluxazole amide and application thereof Download PDFInfo
- Publication number
- CN115812725B CN115812725B CN202210283302.9A CN202210283302A CN115812725B CN 115812725 B CN115812725 B CN 115812725B CN 202210283302 A CN202210283302 A CN 202210283302A CN 115812725 B CN115812725 B CN 115812725B
- Authority
- CN
- China
- Prior art keywords
- insecticidal
- pesticide
- pests
- amide
- fluxazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 45
- 230000000749 insecticidal effect Effects 0.000 title claims abstract description 38
- 150000001408 amides Chemical class 0.000 title claims description 30
- 239000000575 pesticide Substances 0.000 claims abstract description 43
- 241000607479 Yersinia pestis Species 0.000 claims abstract description 40
- YPSCQJTUAKNUNF-UHFFFAOYSA-N 2-chloro-n-[(4-chlorophenyl)carbamoyl]benzamide Chemical compound C1=CC(Cl)=CC=C1NC(=O)NC(=O)C1=CC=CC=C1Cl YPSCQJTUAKNUNF-UHFFFAOYSA-N 0.000 claims abstract description 20
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229910052731 fluorine Inorganic materials 0.000 claims abstract description 9
- 239000011737 fluorine Substances 0.000 claims abstract description 9
- 239000005788 Fluxapyroxad Substances 0.000 claims description 20
- SXSGXWCSHSVPGB-UHFFFAOYSA-N fluxapyroxad Chemical compound FC(F)C1=NN(C)C=C1C(=O)NC1=CC=CC=C1C1=CC(F)=C(F)C(F)=C1 SXSGXWCSHSVPGB-UHFFFAOYSA-N 0.000 claims description 20
- 241000255967 Helicoverpa zea Species 0.000 claims description 12
- 241000346285 Ostrinia furnacalis Species 0.000 claims description 11
- 241000500437 Plutella xylostella Species 0.000 claims description 10
- 230000000361 pesticidal effect Effects 0.000 claims description 10
- 241001600408 Aphis gossypii Species 0.000 claims description 6
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims description 6
- 240000003768 Solanum lycopersicum Species 0.000 claims description 6
- 239000004562 water dispersible granule Substances 0.000 claims description 5
- 239000004563 wettable powder Substances 0.000 claims description 5
- 244000003416 Asparagus officinalis Species 0.000 claims description 4
- 235000005340 Asparagus officinalis Nutrition 0.000 claims description 4
- 240000001307 Myosotis scorpioides Species 0.000 claims description 4
- 239000004495 emulsifiable concentrate Substances 0.000 claims description 4
- 239000000839 emulsion Substances 0.000 claims description 4
- 239000000375 suspending agent Substances 0.000 claims description 4
- 241001425390 Aphis fabae Species 0.000 claims description 3
- 241000426497 Chilo suppressalis Species 0.000 claims description 3
- 241000220225 Malus Species 0.000 claims description 3
- 241001556089 Nilaparvata lugens Species 0.000 claims description 3
- 241000167882 Rhopalosiphum maidis Species 0.000 claims description 3
- 241000125167 Rhopalosiphum padi Species 0.000 claims description 3
- 241000256251 Spodoptera frugiperda Species 0.000 claims description 3
- 238000009472 formulation Methods 0.000 claims description 3
- 239000004530 micro-emulsion Substances 0.000 claims description 3
- 241001166626 Aulacorthum solani Species 0.000 claims description 2
- 241000098289 Cnaphalocrocis medinalis Species 0.000 claims description 2
- 241001477931 Mythimna unipuncta Species 0.000 claims description 2
- 239000011248 coating agent Substances 0.000 claims description 2
- 241001604418 Aromia bungii Species 0.000 claims 1
- 244000089742 Citrus aurantifolia Species 0.000 claims 1
- 235000008733 Citrus aurantifolia Nutrition 0.000 claims 1
- 241001498622 Cixius wagneri Species 0.000 claims 1
- 240000003826 Eichhornia crassipes Species 0.000 claims 1
- 235000011941 Tilia x europaea Nutrition 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000004571 lime Substances 0.000 claims 1
- 239000012053 oil suspension Substances 0.000 claims 1
- 239000004548 suspo-emulsion Substances 0.000 claims 1
- 239000005912 Lufenuron Substances 0.000 abstract description 20
- 229960000521 lufenuron Drugs 0.000 abstract description 20
- 230000000694 effects Effects 0.000 abstract description 19
- 239000005893 Diflubenzuron Substances 0.000 abstract description 18
- 229940019503 diflubenzuron Drugs 0.000 abstract description 18
- PWPJGUXAGUPAHP-UHFFFAOYSA-N lufenuron Chemical compound C1=C(Cl)C(OC(F)(F)C(C(F)(F)F)F)=CC(Cl)=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F PWPJGUXAGUPAHP-UHFFFAOYSA-N 0.000 abstract description 18
- 241000255777 Lepidoptera Species 0.000 abstract description 15
- RGNPBRKPHBKNKX-UHFFFAOYSA-N hexaflumuron Chemical compound C1=C(Cl)C(OC(F)(F)C(F)F)=C(Cl)C=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F RGNPBRKPHBKNKX-UHFFFAOYSA-N 0.000 abstract description 14
- 238000002360 preparation method Methods 0.000 abstract description 13
- HRYILSDLIGTCOP-UHFFFAOYSA-N N-benzoylurea Chemical compound NC(=O)NC(=O)C1=CC=CC=C1 HRYILSDLIGTCOP-UHFFFAOYSA-N 0.000 abstract description 11
- 239000002917 insecticide Substances 0.000 abstract description 10
- 239000005784 Fluoxastrobin Substances 0.000 abstract description 5
- UFEODZBUAFNAEU-NLRVBDNBSA-N fluoxastrobin Chemical compound C=1C=CC=C(OC=2C(=C(OC=3C(=CC=CC=3)Cl)N=CN=2)F)C=1C(=N/OC)\C1=NOCCO1 UFEODZBUAFNAEU-NLRVBDNBSA-N 0.000 abstract description 5
- 150000001875 compounds Chemical class 0.000 abstract description 4
- 240000008042 Zea mays Species 0.000 abstract description 3
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract description 3
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract description 3
- 230000009471 action Effects 0.000 abstract description 3
- 235000005822 corn Nutrition 0.000 abstract description 3
- 229920000742 Cotton Polymers 0.000 abstract description 2
- 206010059866 Drug resistance Diseases 0.000 abstract description 2
- 241000219146 Gossypium Species 0.000 abstract description 2
- 240000007594 Oryza sativa Species 0.000 abstract description 2
- 235000007164 Oryza sativa Nutrition 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract description 2
- 244000037666 field crops Species 0.000 abstract description 2
- 230000007246 mechanism Effects 0.000 abstract description 2
- 235000009566 rice Nutrition 0.000 abstract description 2
- 235000013311 vegetables Nutrition 0.000 abstract description 2
- QQQYTWIFVNKMRW-UHFFFAOYSA-N diflubenzuron Chemical compound FC1=CC=CC(F)=C1C(=O)NC(=O)NC1=CC=C(Cl)C=C1 QQQYTWIFVNKMRW-UHFFFAOYSA-N 0.000 abstract 1
- 230000000856 effect on pests Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 description 29
- 230000001988 toxicity Effects 0.000 description 29
- 239000003795 chemical substances by application Substances 0.000 description 21
- 238000000034 method Methods 0.000 description 19
- XUNYDVLIZWUPAW-UHFFFAOYSA-N (4-chlorophenyl) n-(4-methylphenyl)sulfonylcarbamate Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NC(=O)OC1=CC=C(Cl)C=C1 XUNYDVLIZWUPAW-UHFFFAOYSA-N 0.000 description 14
- 241000238631 Hexapoda Species 0.000 description 13
- -1 aliphatic alcohols Chemical class 0.000 description 13
- 239000004480 active ingredient Substances 0.000 description 12
- 230000002195 synergetic effect Effects 0.000 description 12
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 10
- 238000012360 testing method Methods 0.000 description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 239000002270 dispersing agent Substances 0.000 description 7
- 238000005259 measurement Methods 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 241000256247 Spodoptera exigua Species 0.000 description 6
- 239000000945 filler Substances 0.000 description 6
- 238000002156 mixing Methods 0.000 description 6
- 239000002994 raw material Substances 0.000 description 6
- 230000002829 reductive effect Effects 0.000 description 6
- 239000000080 wetting agent Substances 0.000 description 6
- 240000007124 Brassica oleracea Species 0.000 description 5
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 5
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 5
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- 239000003995 emulsifying agent Substances 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 241000196324 Embryophyta Species 0.000 description 4
- 238000007598 dipping method Methods 0.000 description 4
- 150000002170 ethers Chemical class 0.000 description 4
- 230000005669 field effect Effects 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 229920000151 polyglycol Polymers 0.000 description 4
- 239000010695 polyglycol Substances 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 238000007619 statistical method Methods 0.000 description 4
- 239000004094 surface-active agent Substances 0.000 description 4
- 241000255925 Diptera Species 0.000 description 3
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 3
- 150000001298 alcohols Chemical class 0.000 description 3
- 239000007798 antifreeze agent Substances 0.000 description 3
- 239000012752 auxiliary agent Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 239000004359 castor oil Substances 0.000 description 3
- 235000019438 castor oil Nutrition 0.000 description 3
- 238000013329 compounding Methods 0.000 description 3
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 3
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 3
- 239000012452 mother liquor Substances 0.000 description 3
- 239000010413 mother solution Substances 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 241000238876 Acari Species 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 229920002101 Chitin Polymers 0.000 description 2
- 108010062745 Chloride Channels Proteins 0.000 description 2
- 102000011045 Chloride Channels Human genes 0.000 description 2
- 241001414720 Cicadellidae Species 0.000 description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 241001414989 Thysanoptera Species 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 239000006229 carbon black Substances 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 150000002191 fatty alcohols Chemical class 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- PSZYNBSKGUBXEH-UHFFFAOYSA-N naphthalene-1-sulfonic acid Chemical class C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-N 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 150000002989 phenols Chemical class 0.000 description 2
- 229920000642 polymer Chemical class 0.000 description 2
- 229920000056 polyoxyethylene ether Polymers 0.000 description 2
- 229940051841 polyoxyethylene ether Drugs 0.000 description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 2
- 229920000053 polysorbate 80 Polymers 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 238000002791 soaking Methods 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- WHOZNOZYMBRCBL-OUKQBFOZSA-N (2E)-2-Tetradecenal Chemical class CCCCCCCCCCC\C=C\C=O WHOZNOZYMBRCBL-OUKQBFOZSA-N 0.000 description 1
- FKKAGFLIPSSCHT-UHFFFAOYSA-N 1-dodecoxydodecane;sulfuric acid Chemical class OS(O)(=O)=O.CCCCCCCCCCCCOCCCCCCCCCCCC FKKAGFLIPSSCHT-UHFFFAOYSA-N 0.000 description 1
- NFAOATPOYUWEHM-UHFFFAOYSA-N 2-(6-methylheptyl)phenol Chemical class CC(C)CCCCCC1=CC=CC=C1O NFAOATPOYUWEHM-UHFFFAOYSA-N 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 241000256844 Apis mellifera Species 0.000 description 1
- 102000005469 Chitin Synthase Human genes 0.000 description 1
- 108700040089 Chitin synthases Proteins 0.000 description 1
- 241000008892 Cnaphalocrocis patnalis Species 0.000 description 1
- 241000254173 Coleoptera Species 0.000 description 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical class OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 241000995023 Empoasca Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000258937 Hemiptera Species 0.000 description 1
- 241000282414 Homo sapiens Species 0.000 description 1
- 101100315526 Homo sapiens TUSC2 gene Proteins 0.000 description 1
- 241000257303 Hymenoptera Species 0.000 description 1
- 231100000111 LD50 Toxicity 0.000 description 1
- 229920001732 Lignosulfonate Polymers 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000721621 Myzus persicae Species 0.000 description 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical class OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical compound OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 description 1
- 241001528590 Synanthedon exitiosa Species 0.000 description 1
- 241000255993 Trichoplusia ni Species 0.000 description 1
- 102100036129 Tumor suppressor candidate 2 Human genes 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 125000002877 alkyl aryl group Chemical group 0.000 description 1
- 150000008055 alkyl aryl sulfonates Chemical class 0.000 description 1
- 150000005215 alkyl ethers Chemical class 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 125000005037 alkyl phenyl group Chemical group 0.000 description 1
- 150000008051 alkyl sulfates Chemical class 0.000 description 1
- 229940045714 alkyl sulfonate alkylating agent Drugs 0.000 description 1
- 150000008052 alkyl sulfonates Chemical class 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 230000003042 antagnostic effect Effects 0.000 description 1
- 230000002528 anti-freeze Effects 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 150000007942 carboxylates Chemical class 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 150000008280 chlorinated hydrocarbons Chemical class 0.000 description 1
- 239000004927 clay Substances 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000013530 defoamer Substances 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- LQZZUXJYWNFBMV-UHFFFAOYSA-N dodecan-1-ol Chemical compound CCCCCCCCCCCCO LQZZUXJYWNFBMV-UHFFFAOYSA-N 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 239000010408 film Substances 0.000 description 1
- NVVZQXQBYZPMLJ-UHFFFAOYSA-N formaldehyde;naphthalene-1-sulfonic acid Chemical compound O=C.C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 NVVZQXQBYZPMLJ-UHFFFAOYSA-N 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 238000009775 high-speed stirring Methods 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- CTAPFRYPJLPFDF-UHFFFAOYSA-N isoxazole Chemical compound C=1C=NOC=1 CTAPFRYPJLPFDF-UHFFFAOYSA-N 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- 238000012417 linear regression Methods 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- LCRMGUFGEDUSOG-UHFFFAOYSA-N naphthalen-1-ylsulfonyloxymethyl naphthalene-1-sulfonate;sodium Chemical compound [Na].C1=CC=C2C(S(=O)(OCOS(=O)(=O)C=3C4=CC=CC=C4C=CC=3)=O)=CC=CC2=C1 LCRMGUFGEDUSOG-UHFFFAOYSA-N 0.000 description 1
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical class CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 1
- 229920002114 octoxynol-9 Polymers 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 229940044654 phenolsulfonic acid Drugs 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000009044 synergistic interaction Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical class NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 1
- 239000013008 thixotropic agent Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention discloses a fluorine-containing oxazamide insecticidal composition and application thereof, and belongs to the technical field of insecticidal pesticides. The insecticidal composition containing the fluorine oxazamide comprises the fluorine oxazamide and at least one benzoyl urea insecticide; the weight ratio of the fluoxastrobin to the benzoylurea insecticide is 10:1-1:40. The benzoyl urea insecticide can be at least one of lufenuron, chlorbenzuron, diflubenzuron and hexaflumuron. The insecticidal composition has completely different action mechanisms of the fluxazolamide and the benzoyl urea insecticide, and the compound can synergistically increase the effect on pests, improve the control effect, reduce the use amount of pesticides, delay the generation of drug resistance and reduce the resistance risk. The composition of the invention is prepared into pesticide preparations, and can be used for preventing and controlling lepidoptera pests and piercing-sucking mouthpart pests of horticultural crops such as vegetables, fruit trees and the like, and field crops such as corn, cotton, rice and the like.
Description
Technical Field
The invention belongs to the technical field of insecticidal pesticides, and particularly relates to an insecticidal composition containing fluxapyroxad and application thereof.
Background
In recent years, with the change of cultivation and cultivation system, the occurrence degree of pests is increased year by year, and the crop yield and quality are seriously affected. Chemical pest control is the most economical and effective means in pest control, and the application of pesticides to control pests has extremely important significance in recovering crop yield loss and improving commodity and quality of agricultural products.
Fluximamide (Fluximamide) is a novel isoxazole pesticide, is developed by Japanese chemical Co., ltd., has broad-spectrum bioactivity, has special efficacy on lepidoptera pests, and can prevent and treat pests such as acarina, thysanoptera, diptera and the like. The novel action mechanism of the fluxazolamide belongs to a glutamic acid-gated chloride channel (LGCC) interfering agent, and mainly acts on gamma-aminobutyric acid-gated chloride channel (GABACI) of insects.
The benzoyl urea pesticide can inhibit chitin synthesis by inhibiting insect chitin synthase activity, so that the insect chitin is reduced in feeding, slowed in activity or molted or pupated and finally dead, has high activity on lepidoptera larvae, and has effects on pests such as diptera, coleoptera and hymenoptera, and has a long lasting period. The pesticide mainly has stomach toxicity effect, low contact activity, relatively slow drug effect, easy decomposition in animals and plants, soil and water, small residue, and safety to human, livestock and bee.
In the process of using pesticides to control pests, the chemical pesticides of a single variety or a single action mode are continuously used for a long time in high dosage, so that the problems of pest resistance, resistance evolution and the like are easily caused. The reasonable compounding or compounding of the pesticide compound has the advantages of reducing the dosage of the pesticide, improving the control effect, delaying the occurrence and development of the pesticide resistance of pests, and the like, and is one of the most effective methods for solving the problems.
Disclosure of Invention
Aiming at the problems of easy drug resistance and resistance evolution of pests and the like caused by using a single variety or a single-action mode chemical pesticide continuously and in a high dosage for a long time in the prior art, the invention provides a fluorine-containing oxazamide insecticidal composition and application thereof.
In order to achieve the above purpose, the invention adopts the following technical scheme:
an insecticidal composition comprising a fluxazole amide, the insecticidal composition comprising a fluxazole amide and at least one benzoylurea insecticide; the weight ratio of the fluoxastrobin to the benzoylurea insecticide is 10:1-1:40.
In several specific embodiments, the benzoylurea insecticide may be at least one of lufenuron, chlorbenzuron, diflubenzuron, hexaflumuron.
In several specific embodiments, the weight ratio of the fluxapyroxad to lufenuron is from 1:1 to 1:20; the weight ratio of the fluxazole amide to the hexaflumuron is 1:1-1:10; the weight ratio of the fluxapyroxad to the chlorbenzuron is 1:2-1:40; the weight ratio of the fluoxastrobin to the diflubenzuron is 1:2-1:20, and in the weight ratio range, the technical effect of synergistic interaction is achieved by mixing the fluoxastrobin and the benzoyl urea pesticide.
The application of the insecticidal composition containing the fluorine oxazamide in preparing insecticidal pesticides, wherein the insecticidal pesticides are used for preventing and controlling lepidoptera pests and piercing-sucking mouthpart pests.
The insecticidal pesticide containing the fluorine-containing oxazamide comprises the insecticidal composition containing the fluorine-containing oxazamide, wherein the mass percentage of the insecticidal composition accounts for 1-95% of the total pesticide, and is preferably 10-80%; in general, the insecticidal compositions of the present invention comprise 1 to 95 parts by weight of active ingredient and 5 to 99 parts by weight of conventional adjuvants for pesticides.
Conventional adjuvants in such pesticidal pesticides may include carriers, surfactants, and the like, wherein the surfactants include, for example, quaternary, dispersing and wetting agents, which may be ionic or nonionic. Examples which may be mentioned are salts of polyacrylic acid, lignosulfonates, salts of phenolsulfonic acid or naphthalenesulfonic acid, polymers of ethylene oxide with aliphatic alcohols or with aliphatic amines with substituted phenols, in particular alkylphenols or arylphenols, sulfosuccinates, taurine derivatives, in particular taurates, and phosphates of alcohols or of polyethylated phenols, alkylsulfonates, alkylaryl sulfonates, alkyl sulfates, lauryl ether sulfates, fatty alcohol sulfates, and also sulfated hexadecyl-, heptadeca-and octadecanols and sulfated fatty alcohol glycol ethers, furthermore condensates of naphthalene or naphthalenesulfonic acid with phenol and formaldehyde, polyoxyethylene octylphenyl ether, ethoxylated isooctylphenols, octylphenols or nonylphenols, alkylphenyl polyglycol ethers, tributylphenyl polyglycol ethers, tristearylphenyl polyglycol ethers, alkylaryl polyether alcohols, alcohol and fatty alcohol/ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ethers, sorbitol esters, lignin sulfite waste solutions, and also proteins, polysaccharides (e.g. methylcellulose), polyvinyl alcohol, hydrophobically modified polyvinyl pyrrolidone, polyvinyl alcohol carboxylate, polyvinyl pyrrolidone, and copolymers thereof. At least one surfactant is required to be present to facilitate the dispersion of the active ingredients in water and to enable them to be applied correctly to the plants. A step of
The carrier means an organic or inorganic, natural or synthetic substance. They facilitate the application of the active ingredient, which carriers are generally inert and must be agriculturally acceptable, in particular by the treated plants. The carrier may be solid, such as clay, natural or synthetic silicate, silica, resin, wax, solid fertilizer, etc.; or liquid, such as water, alcohols, ketones, petroleum fractions, aromatic or waxy hydrocarbons, chlorinated hydrocarbons, liquefied gases, and the like.
The pesticidal pesticides may also contain various other components such as solvents, antifreeze agents, disintegrants, protective colloids, binders, thickeners, thixotropic agents, penetrants, stabilizers, chelating agents, film formers, dyes, colorants and polymers.
The specific formulation of the insecticidal pesticide is one of wettable powder, dispersible oil suspending agent, suspending seed coating agent, suspending emulsion, water dispersible granule, emulsifiable concentrate, aqueous emulsion and microemulsion.
Adding the raw materials, the safener, the solvent and the emulsifier in the formula into a mother liquor preparation kettle to prepare a uniform oil phase, uniformly mixing deionized water, an antifreeze agent and the like, injecting the mixture into the product preparation kettle, and uniformly mixing the mixture by high-speed stirring to prepare the transparent or semitransparent microemulsion product of the insecticidal pesticide.
Briefly, the pesticidal pesticides of the present invention may be mixed with solid and liquid additives conventionally used in prior art formulations.
The fluxapyroxad and the benzoylurea insecticides such as lufenuron, chlorbenzuron, diflubenzuron and hexaflumuron have broad-spectrum insecticidal activity and have higher activity on piercing-sucking mouthparts of lepidoptera, acarina, thysanoptera, diptera and the like, so that the insecticidal pesticide containing the fluxapyroxad can be used for preventing and controlling lepidoptera pests and piercing-sucking mouthparts of the pests, wherein the lepidoptera pests are at least one of cotton bollworms, beet armyworms, spodoptera frugiperda, plutella xylostella, corn borers, peach borers, chilo suppressalis and rice leaf rollers; the piercing-sucking mouthpart pest is at least one of wheat aphid, cotton aphid, corn aphid, bean aphid, potato aphid, apple cotton aphid, tomato white fly, brown planthopper, empoasca pseudoeye and leafhopper.
The pesticidal pesticide may be diluted by the user before use or used directly. The preparation can be prepared by common processing method, namely, mixing the active substance with liquid solvent or solid carrier, and adding one or more surfactants such as dispersing agent, stabilizer, wetting agent, adhesive, defoamer, etc.
The insecticidal pesticide can be applied to leaves and seeds of plants to be treated by spraying and seed treatment. The experimental study shows that the active ingredients of the insecticidal pesticide disclosed by the invention have obvious synergistic effect between the fluxazole amide and the benzoylurea insecticide. The synergistic effect is expressed by reduced application amount, faster and longer insecticidal action.
The technical scheme of the invention has the advantages that:
(1) The insecticidal composition disclosed by the invention is an environment-friendly insecticide, is easy to degrade in the environment and is safe to crops.
(2) The insecticidal composition provided by the invention has the characteristics of convenience in use and easiness in popularization, and has great economic and social benefits.
(3) Compared with the prior art, the composition of the invention is prepared into pesticide preparations, and can be used for preventing and controlling lepidoptera pests and piercing-sucking mouthpart pests of horticultural crops such as vegetables, fruit trees and the like, and field crops such as corn, cotton, rice and the like. The lepidoptera pests are cotton bollworms, asparagus caterpillar, armyworms, spodoptera frugiperda, corn borers, carpopodium borers, chilo suppressalis, cnaphalocrocis medinalis and the like, and the sucking type mouth parts pests are wheat aphids, cotton aphids, corn aphids, bean aphids, potato aphids, apple cotton aphids, tomato white flies, brown planthoppers, pseudoeye leafhoppers and the like.
Detailed Description
The terms used in the present invention generally have meanings commonly understood by those of ordinary skill in the art unless otherwise indicated.
The invention will be described in further detail below in connection with specific embodiments and with reference to the data. The following examples are intended to illustrate the invention and are not intended to limit the scope of the invention in any way.
Example 1
An insecticidal composition of fluxazole amide and lufenuron, wherein the weight ratio of the fluxazole amide to the lufenuron is 10:1-1:40.
Prevention and treatment effect of fluxapyroxad and lufenuron on pests (indoor toxicity measurement)
Test agent: fluoxazolamide and lufenuron as raw material. Dissolving the raw materials of the fluxapyroxad and the lufenuron in acetone, preparing 10000mg/kg mother solution, and storing in a refrigerator at 4 ℃ for standby.
Test insects: cotton bollworm 3-instar larvae.
The measuring method comprises the following steps: taking lepidoptera pests cotton bollworm as an example, the toxicity of the fluxapyroxad, lufenuron and the mixed preparation thereof to the lepidoptera pests is measured by adopting a leaf dipping method.
Single dose toxicity determination method:
the leaf soaking method is adopted, firstly, the test reagent (fluxazolamide and lufenuron) is prepared into 10000mg/kg mother liquor by acetone, then 5 concentration gradients are prepared by 0.1% Tween-80 solution according to an equal ratio method, and 0.1% Tween-80 solution is used as a control. Washing the surface waxy layer with washing powder without using the leaf, airing, punching into round leaves with the diameter of 1.5cm by using a puncher, soaking in the liquid medicine for 10 seconds, taking out, airing on absorbent paper, putting into 24-hole insect breeding plates, putting 2 leaves in each hole, accessing 1 head of larva, putting into a 27 ℃ illumination incubator, and investigating the number of living insects after 72 hours. For each 3 replicates treated, DSP was used to determine virulence regression equations, median lethal concentration (LC 50) and 95% confidence intervals.
Determination of combined toxicity of the mixture:
based on the single dose toxicity measurement, the mixed active component A (fluxapyroxad) and the active component B (lufenuron) are respectively mixed according to LC 50 The value dose is respectively set to 9 ratios of 10:1, 5:1, 2:1, 1:1, 1:2, 1:5, 1:10, 1:20 and 1:40 according to the weight ratio, 5 series concentration gradients are prepared according to different ratios, and each treatment is repeated for 3 times. Obtaining the medium-concentration LC of the mixed medicament for killing the cotton bollworms by linear regression analysis between the death rate of the insect population and the logarithmic value of the medicament concentration 50 Values and CTC values.
Statistical analysis of data
The test data are statistically analyzed by Microsoft Excel 2016 and DPS data processing platform to calculate LC of each agent 50 Value, 95% confidence limit. And calculating the co-toxicity coefficient of the mixed agent by using a grand cloud Peel method (1960), and evaluating the synergistic effect of the mixed agent according to the co-toxicity coefficient.
The inhibition of each agent was calculated according to the following formula:
insect population mortality (%) =number of dead insect population/total number of treated insects×100
Corrected mortality (%) = [ (treated group port mortality-control group port mortality)/(1-control group port mortality) ]100
Toxicity index ti= (standard agent LC 50 Reagent LC 50 )×100
Actual toxicity index ati= (Standard agent LC) 50 Compounding LC 50 )×100
Theoretical toxicity index of the mixture tti=ti×pa of the single agent a+ti×pb of the single agent B (PA and PB are the percentage of active ingredients in the mixture, respectively)
Co-toxicity coefficient CTC = actual toxicity index of the compound ATI/theoretical toxicity index of the compound TTI x 100
Judging the synergy: CTC is more than or equal to 120, and has synergistic effect; CTC is 80 < 120, which is additive; CTC is less than or equal to 80, and is antagonistic.
Results and analysis: as shown in table 1.
TABLE 1 toxicity test results of Fuxazolamide, lufenuron and mixtures thereof on cotton bollworms
As can be seen from table 1, the fluxazole amide, the lufenuron and the mixture thereof have higher indoor toxicity to cotton bollworms, wherein when the ratio of the fluxazole amide to the lufenuron is between 1:1 and 1:20, the co-toxicity coefficient to cotton bollworms is above 120, which indicates that the two pesticides have good synergistic effect under the ratio.
Example 2
The insecticidal composition of the fluxazole amide and the hexaflumuron, wherein the weight ratio of the fluxazole amide to the hexaflumuron is 10:1-1:40.
Fusoxazole amide and hexaflumuron are compounded to prevent and treat pests (indoor toxicity measurement)
Test agent: the original drug of the fluxazole amide and the hexaflumuron. Dissolving the raw materials of the fluxazole amide and the hexaflumuron in acetone, preparing 10000mg/kg mother solution, and storing in a refrigerator at 4 ℃ for standby.
Test insects: beet armyworm 3-instar larvae.
The measuring method comprises the following steps: taking spodoptera exigua as an example, the toxicity of the fluxapyroxad, hexaflumuron and the mixed preparation thereof to the lepidoptera exigua is measured by adopting a leaf dipping method.
The method for measuring toxicity of single dose, the method for measuring toxicity of combination of mixed agents and the method for statistical analysis of data are the same as in example 1.
Results and analysis: as shown in table 2.
TABLE 2 toxicity measurement results of Furazolam, furazolides and mixtures thereof on asparagus caterpillar
As can be seen from table 2, the fluxazole amide, the hexaflumuron and the mixture thereof have higher indoor toxicity to the spodoptera exigua, wherein when the ratio of the fluxazole amide to the hexaflumuron is between 1:1 and 1:10, the co-toxicity coefficient to the spodoptera exigua is above 120, which indicates that the two pesticides have good synergistic effect under the ratio.
Example 3
The insecticidal composition of the fluxazole amide and the chlorbenzuron, wherein the weight ratio of the fluxazole amide to the chlorbenzuron is 10:1-1:40.
Fusoxazole amide and chlorbenzuron are compounded to prevent and treat pests (indoor toxicity measurement)
Test agent: fuxazolamide and chlorbenzuron as raw material. Dissolving the raw materials of the fluxapyroxad and the chlorbenzuron in acetone, preparing 10000mg/kg mother solution, and storing in a refrigerator at 4 ℃ for standby.
Test insects: plutella xylostella 3-instar larvae.
The measuring method comprises the following steps: taking lepidoptera insect plutella xylostella as an example, the toxicity of the fluxamide, the chlorbenzuron and the mixed preparation thereof to the lepidoptera insect is measured by adopting a leaf dipping method.
The method for measuring toxicity of single dose, the method for measuring toxicity of combination of mixed agents and the method for statistical analysis of data are the same as in example 1.
Results and analysis: as shown in table 3.
TABLE 3 toxicity measurement results of Fuxazolamide, chlorbenzuron and mixtures thereof on Plutella xylostella
As shown in table 3, the fluxazole amide, the chlorbenzuron and the mixture thereof have higher indoor toxicity to the plutella xylostella, wherein when the ratio of the fluxazole amide to the chlorbenzuron is between 1:2 and 1:40, the co-toxicity coefficient to the plutella xylostella is above 120, which indicates that the two pesticides have good synergistic effect under the ratio.
Example 4
An insecticidal composition of the fluxazole amide and the diflubenzuron, wherein the weight ratio of the fluxazole amide to the diflubenzuron is 10:1-1:40.
Prevention and treatment effect of the combination of the fluxapyroxad and the diflubenzuron on pests (indoor toxicity measurement)
Test agent: the original drug of the fluxazole amide and the diflubenzuron. Dissolving the fluoxastrobin and diflubenzuron in acetone, preparing 10000mg/kg mother liquor, and storing in refrigerator at 4deg.C.
Test insects: corn borer 3-instar larvae.
The measuring method comprises the following steps: taking lepidoptera pests, such as corn borer, as an example, a leaf dipping method is adopted to measure toxicity of the fluxazolamide, the diflubenzuron and the mixed preparation thereof to the lepidoptera pests.
The method for measuring toxicity of single dose, the method for measuring toxicity of combination of mixed agents and the method for statistical analysis of data are the same as in example 1.
Results and analysis: as shown in table 4.
TABLE 4 toxicity determination results of Fuxazolamide, diflubenzuron and mixtures thereof on corn borers
As shown in table 4, the fluxazole amide, the diflubenzuron and the mixture thereof have higher indoor toxicity to corn borers, wherein when the ratio of the fluxazole amide to the diflubenzuron is between 1:2 and 1:20, the co-toxicity coefficient to the corn borers is over 120, which indicates that the two pesticides have good synergistic effect under the ratio.
Example 5
24% of fluxazolamide-lufenuron emulsifiable concentrate comprises the following components in percentage by weight:
4% of fluxazoxamide, 20% of lufenuron, 25% of cyclohexane (solvent), 3% of agro-emulsion No. 600 (commercial, emulsifier), 5% of castor oil polyethylene glycol condensation (emulsifier), 4% of glycerol (antifreeze) and the balance of xylene to 100%.
The preparation method comprises the following steps: and (3) fully mixing the active ingredients, various auxiliary agents and dimethylbenzene according to a proportion, adding the mixture into a mixing kettle, and uniformly stirring to obtain 24% fluxapyroxad-lufenuron missible oil.
The embodiment is applied to control of tomato cotton bollworms, enters the initial period of pests, and is sprayed by adding water with different concentrations. The control effect is shown in the following table 5.
Table 5 field effect of 24% fluxazolamide lufenuron emulsifiable concentrate for controlling tomato bollworm
As can be seen from table 5, the synergistic effect of the fluxapyroxad and lufenuron is obvious after being mixed, the control effect on tomato bollworms is obviously better than that of single dosage, and the dosage of the active ingredients is obviously reduced.
Example 6
24% of fluxazolamide-hexaflumuron water dispersible granule comprises the following components in percentage by weight:
4% of fluxazolamide, 20% of hexaflumuron, 5% of alkyl naphthalene sulfonate formaldehyde condensate (dispersing agent), 5% of sodium lignin sulfonate (dispersing agent), 2% of methylene dinaphthalene sulfonate sodium (wetting agent), 3% of ammonium sulfate (disintegrating agent), 30% of white carbon black (filler) and 100% of calcium carbonate (filler).
The preparation method comprises the following steps: the active ingredients, sodium alkyl naphthalene sulfonate formaldehyde condensate, wetting agent, disintegrating agent and filler are fully mixed according to a proportion, crushed to a particle size of 5 mu m by a jet mill to obtain mother powder, and the mother powder and sodium lignin sulfonate are fully mixed, granulated, dried and sieved to obtain 24% fluoxastrobin-hexaflumuron water dispersible granules.
The embodiment is applied to control cabbage asparagus caterpillar, enters the initial period of pest occurrence, and is sprayed by adding water with different concentrations. The control effect is shown in Table 6 below.
Table 6 24% Fuxazolamide-hexaflumuron water dispersible granule for controlling cabbage beet armyworm field effect
As can be seen from Table 6, the synergistic effect of the mixed fluxapyroxad and the hexaflumuron is obvious, the prevention and control effect on cabbage looper is obviously better than that of a single agent, and the dosage of the active ingredients is obviously reduced.
Example 7
22% of fluxapyroxad/chlorbenzuron wettable powder comprises the following components in percentage by weight:
2% of fluxazolamide, 20% of chlorbenzuron, 2% of alkyl naphthalene sulfonate formaldehyde condensate (dispersing agent), 3% of sodium lignin sulfonate (dispersing agent), 3% of sodium dodecyl sulfate (wetting agent), 20% of white carbon black (filler) and 100% of kaolin (filler).
The preparation method comprises the following steps: the active ingredients, various auxiliary agents and fillers are fully and uniformly mixed according to a proportion, and the mixture is crushed by a superfine crusher to prepare 22% fluxazolamide and chlorbenzuron wettable powder.
The embodiment is applied to cabbage plutella xylostella, enters the initial period of pests, and is sprayed by adding water with different concentrations. The control effect is shown in Table 7 below.
Table 7 22% Fuxazolamide and chlorbenzuron wettable powder for controlling cabbage plutella xylostella field effect
As can be seen from Table 7, the synergistic effect of the fluxapyroxad and chlorbenzuron is obvious after being mixed, the control effect on cabbage diamondback moth is obviously better than that of a single agent, and the dosage of the active ingredients is obviously reduced.
Example 8
22% of a fluoxastrobin-diflubenzuron suspending agent comprises the following components in percentage by weight:
2% of fluxazolamide, 20% of diflubenzuron, 5% of alkyl naphthalene sulfonate sodium formaldehyde condensate (dispersing agent), 3% of castor oil polyoxyethylene ether (emulsifying agent), 5% of fatty alcohol polyoxyethylene ether (emulsifying agent), 3% of methylene dinaphthyl sulfonate sodium (wetting agent), 2% of xanthan gum (thickening agent), 4% of glycerol (antifreeze agent) and the balance of water to 100%.
The preparation method comprises the following steps: the active ingredients, various auxiliary agents and water are fully and uniformly mixed according to a proportion, and are put into a sand mill to be ground to the particle size of 5 mu m, so as to prepare the 22% fluoxastrobin-diflubenzuron suspending agent.
The embodiment is applied to preventing and controlling corn borers, and spraying water with different concentrations at the initial stage of the occurrence of the corn large horn mouth pests. The control effect is shown in the following table 8.
Table 8 field effect of 22% Fuxazolamide-diflubenzuron suspension for controlling corn borer
As can be seen from Table 8, the synergistic effect of the fluxapyroxad and the diflubenzuron is obvious after being mixed, the control effect on corn borer is obviously better than that of a single agent, and the dosage of the effective components is obviously reduced.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the invention in any way, and any person skilled in the art may make modifications or alterations to the disclosed technical content to the equivalent embodiments. However, any simple modification, equivalent variation and variation of the above embodiments according to the technical substance of the present invention still fall within the protection scope of the technical solution of the present invention.
Claims (9)
1. An insecticidal composition comprising a fluxazole amide, wherein the insecticidal composition comprises a fluxazole amide and chlorbenzuron; the weight ratio of the fluxapyroxad to the chlorbenzuron is 1:2-1:40.
2. Use of the pesticidal composition containing the fluxapyroxad according to claim 1 for preparing pesticidal pesticides.
3. The use according to claim 2, wherein the pesticidal pesticide is for controlling lepidopteran pests and sucking mouth parts pests.
4. An insecticidal pesticide containing the fluorine-containing oxazamide, which is characterized by comprising the insecticidal composition containing the fluorine-containing oxazamide according to claim 1, wherein the mass percentage of the insecticidal composition accounts for 1-95% of the total pesticide.
5. The insecticidal pesticide containing the fluxazoxamide according to claim 4, wherein the specific formulation of the insecticidal pesticide is one of wettable powder, dispersible oil suspension, suspending agent, suspended seed coating, suspoemulsion, water dispersible granule, emulsifiable concentrate, aqueous emulsion and microemulsion.
6. Use of the pesticidal pesticide containing the fluxazole amide according to claim 5 for controlling lepidopteran pests and sucking type mouth parts pests.
7. The use according to claim 6, wherein the lepidopteran pest is at least one of cotton bollworm, asparagus caterpillar, armyworm, spodoptera frugiperda, plutella xylostella, corn borer, peach borer, chilo suppressalis, cnaphalocrocis medinalis.
8. The use according to claim 6, wherein the sucking mouth set pest is at least one of wheat aphid, cotton aphid, corn aphid, bean aphid, potato aphid, apple cotton aphid, tomato white fly, lime plant hopper, brown plant hopper, eichhornia crassipes.
9. The pesticidal pesticide containing the fluxapyroxad according to claim 4, wherein the mass percentage of the pesticidal composition accounts for 10-80% of the total pesticide.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210283302.9A CN115812725B (en) | 2022-03-22 | 2022-03-22 | Insecticidal composition containing fluxazole amide and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210283302.9A CN115812725B (en) | 2022-03-22 | 2022-03-22 | Insecticidal composition containing fluxazole amide and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115812725A CN115812725A (en) | 2023-03-21 |
| CN115812725B true CN115812725B (en) | 2024-04-05 |
Family
ID=85522474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210283302.9A Active CN115812725B (en) | 2022-03-22 | 2022-03-22 | Insecticidal composition containing fluxazole amide and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115812725B (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106659160A (en) * | 2014-06-30 | 2017-05-10 | 日产化学工业株式会社 | Insecticide, miticide, nematicide, molluscicide, disinfectant, or bactericide composition, and pest control method |
-
2022
- 2022-03-22 CN CN202210283302.9A patent/CN115812725B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106659160A (en) * | 2014-06-30 | 2017-05-10 | 日产化学工业株式会社 | Insecticide, miticide, nematicide, molluscicide, disinfectant, or bactericide composition, and pest control method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN115812725A (en) | 2023-03-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102379308A (en) | Mixed insecticidal composition containing clothianidin and application of mixed insecticidal composition | |
| CN101406195B (en) | Composition containing ethiprole and avermectin with synergistic disinsection function | |
| CN104585224A (en) | Pesticide composition containing fluensulfone and pyrethroid insecticide | |
| KR20120106941A (en) | Method for reducing pistillate flower abortion in plants | |
| CN115812725B (en) | Insecticidal composition containing fluxazole amide and application thereof | |
| CN110495463B (en) | Synergistic pesticide composition containing trifluoro-benzene pyrimidine and application thereof | |
| CN105532719A (en) | Weeding composition and application and preparation thereof | |
| CN109845740B (en) | Insecticidal composition containing flucloxapyroxad and bishydrazide insecticide | |
| CN102027967B (en) | Pesticide composition containing pyriproxyfen and metaflumizone and application thereof | |
| CN109258651A (en) | A kind of Pesticidal combination containing bromine worm fluorobenzene bisamide and capillary | |
| CN101690493B (en) | Pesticide composition of thiamethoxam and application thereof | |
| CN111789123A (en) | Insecticidal composition containing fluorine-containing chlorantraniliprole | |
| CN112568224B (en) | Insecticidal composition containing chlorfenapyr flubendiamide and diafenthiuron | |
| CN106879609A (en) | A kind of Pesticidal combination containing doractin and Nylar | |
| CN102388906A (en) | Synergistic insecticidal composition containing clothianidin and pymetrozine, and application thereof | |
| CN105265460B (en) | Insecticide acaricide composition and its application | |
| CN116849224A (en) | Insecticidal composition containing isoxazole insect amide and application thereof | |
| CN105028442A (en) | Insecticidal composition containing diflubenzuron and pymetrozine and application thereof | |
| WO2015135423A1 (en) | Pesticidal composition and method for same for controlling pests | |
| CN113796384B (en) | Insecticidal composition containing bistrifluron and chlorfenapyr | |
| CN117814244A (en) | Synergistic insecticidal composition containing Benzpyrimoxan and application thereof | |
| CN109845746B (en) | Insecticidal composition containing flucloxapyroxad and biological insecticide | |
| CN107372541A (en) | A kind of Pesticidal combination containing doractin and Nylar | |
| CN108402073B (en) | Biopesticide composition for preventing and treating rice pests and application thereof | |
| CN107087637A (en) | A kind of nematicide containing methyl jasmonate and fosthiazate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |