WO2015135423A1 - Pesticidal composition and method for same for controlling pests - Google Patents

Abstract

The present invention relates to a pesticidal composition, comprising pyrifluquinazon and ethofenprox, and specifically relates to a method for controlling pests. The pesticidal composition comprising pyrifluquinazon and ethofenprox has a weight ratio of pyrifluquinazon to ethofenprox of 1:100 to 100:1. A method for preventing or controlling pests: using the pesticidal composition on a target useful plant, a target pest or an environment thereof, and a reproductive material for the target useful plant. A method for protecting plant seeds, comprising: allowing seeds to be in contact with an efficacious dose of the pesticidal composition of the present invention before sowing and/or after germination. A seed administered and treated with an efficacious dose of the pesticidal composition of the present invention.

Description

Insecticidal composition and method for controlling same Technical field

The present invention relates to a pesticidal composition comprising flufenicol and fenthrin; in particular to a method of controlling pests.

Background technique

At present, the main method for the prevention and control of pests that are resistant to agriculture is to develop a new component that has no cross-resistance with existing varieties or a compound between existing pesticides. The former has high development cost and long cycle. And the current development speed is far less than the speed of pest resistance. Therefore, it is an optimal choice for the mixing of existing pesticides with different mechanisms of action. If the ratio is reasonable, it can produce significant synergistic effects, making the field control effect significantly better than the effects of each single agent. Insecticides containing a single active ingredient often have certain defects in the control of agricultural pests. Continuous use for many times not only makes the pests susceptible to drug resistance, but also easily causes pollution to food and the environment, and is reasonable between the active ingredients of the pesticide. Compounding can overcome the above disadvantages. At the same time, rational compounding can increase the synergistic effect of the active ingredients, improve the control effect, reduce the amount of active ingredients, save costs, delay the production of insecticide resistance, and can reduce or even avoid the pollution of food and environment by pesticides. The low-toxic and high-efficiency new pesticide developed by the invention not only has a significant effect on the target, but also has a low impact on humans, crops, non-targets and the environment.

Pyrifluquinazon, chemical formula: 1-acetyl-1,2,3,4-tetrahydro-3-[(3-pyridylmethyl)amino]-6-[1,2,2, 2-Tetrafluoro-1-(trifluoromethyl)ethyl]quinazolin-2-one, flufenicol is known and described, for example, in EP 1097932; the structural formula is:

Flumazepam is developed by the Japanese Pesticide Company and belongs to a class of new quinazoline (m-diazabenzene) insecticides. Flumazepam is generally applied as a water-dispersible granule. Its mechanism of action is to stop the pests from feeding and starvation, thereby preventing plant tissues from suffering more damage and limiting the spread of some important diseases. At present, it is mainly used to control whiteflies, mites and scale insects on vegetables, fruit trees and tea leaves.

The chemical name of Ethofenprox is 2-(4-ethoxyphenyl)-2-methylpropyl-3-phenoxybenzyl ether, and its structural formula is:

Ethyl pyrethroid has the characteristics of wide insecticidal spectrum, high insecticidal activity, fast knockdown speed, long residual period and safe crops. It has contact, stomach and systemic effects. For the control of Lepidoptera, Hemiptera, Coleoptera, Diptera, Orthoptera and Isoptera, such as brown planthopper, whitebacked planthopper, black-tailed leafhopper, cotton bollworm, red bollworm, peach aphid, Melon, whitefly, cabbage caterpillar, tea caterpillar, tea mites, tea thorn moth, peach and pear small heartworm, citrus leaf miner, tobacco noctuid, diamondback moth, corn borer, giant salamander, soybean heartworm. However, it has no systemic conduction effect on pests, and has less lethal effect on natural enemies such as rice field spiders, and is ineffective against aphids.

At present, due to the long-term use of etofenol alone, although the number of pests can be inhibited during the initial use of pests, the quick-acting effect is good, but when the pests have occurred in a large amount, the number of pests cannot be controlled, so the persistence is not good, and it is easy. Resistance is produced; and the mechanism of action of flufenicol is to stop the pests from feeding and starve to death, and relatively quick-acting but effective.

A typical need in the field of pest control is the need to reduce the dose rate of the active ingredient and to reduce or avoid adverse environmental or toxicological effects while still allowing effective pest control. There is also a need for a pest control agent that combines knockdown activity and prolonged control time, ie, rapid action and long-acting action.

Another difficulty with the use of insecticides is that repeated and unique use of a single insecticidal compound in many cases results in a rapid selection of pests that produce natural or adaptive resistance to the active compound. Therefore, there is a need for pest control agents that help prevent or overcome drug resistance.

Summary of the invention

The object of the present invention is to solve the above technical problems, and the present invention provides a pesticide composition and a method for controlling the same, which have synergistic effects on controlling pests and effectively alleviate pests Resistance.

Accordingly, it is an object of the present invention to provide a pesticidal composition which solves at least one of the problems, such as reducing the dose rate, expanding the spectrum of activity or combining knockdown activity and prolonging the control time or drug resistance, and delaying the resistance.

The technical solution adopted by the present invention to solve the technical problems thereof is as follows:

A pesticidal composition comprising a first active ingredient and a second active ingredient, the first active ingredient being flubenzure, and the second active ingredient being a weight of the cypermethrin, flubenzure and ether fenthrin The ratio is 1:100-100:1.

As a further improvement of the present invention, the ratio of the ratio of the flufenicol and the permethrin is 1:50 to 50:1.

As a further improvement of the present invention, the flupirizine and the fenthrin have a weight ratio of 1:25 to 25:1.

As a further improvement of the present invention, the flupirizine and the fenthrin have a weight ratio of 1:10 to 10:1.

A pesticidal composition comprising a first active ingredient, flubenzuron and a second active ingredient, fenthrin, the total weight of the first active ingredient flufenicol and the second active ingredient methrin combined in the combination The content is 5%-90% by weight.

A pesticidal composition comprising a first active ingredient, fluprospore, and a second active ingredient, fenthrin, wherein the first active ingredient flufenicol and the second active ingredient, fenthrin, together comprise the composition 10%-80% by weight.

A pesticidal composition comprising a first active ingredient, flubenzuron, and a second active ingredient, fenthrin, wherein the first active ingredient flufenicol and the second active ingredient, fenthrin, together comprise the composition 20%-60% by weight.

The pesticidal composition according to the present invention further comprises a surfactant and/or a extender.

According to the pesticidal composition of the present invention, the pesticidal composition can be formulated into any dosage form that is agriculturally acceptable.

According to the pesticidal composition of the present invention, the insecticidal composition is in the form of an emulsifiable concentrate, a suspending agent, a seed treatment agent, a water-dispersible granule, a wettable powder, a suspoemulsion, an aerosol, an aqueous emulsion, a microcapsule suspension, Microcapsule suspension-suspension, ultra-low volume liquid, microemulsion.

In another aspect, the invention also provides a use of the pesticidal composition of the invention for the prevention or control of pests.

The insecticidal composition is used for preventing or controlling the use of pests on cereals, vegetables, fruit trees, and flowers.

As a further improvement of the present invention, the insecticidal composition is resistant to rice planthopper, thrips, whitefly, aphid, brown planthopper, whitebacked planthopper, black-tailed spider mite, cotton bollworm, red bollworm, and peach aphid , melon, whitefly, cabbage caterpillar, tea caterpillar, tea mites, tea thorn moth, small heartworm, citrus leaf miner, tobacco nocturnal moth, diamondback moth, corn borer, big cockroach, heartworm.

In another aspect, the present invention provides a method for preventing or controlling a pest, which comprises applying the pesticidal composition of the present invention to a target useful plant, a target pest or an environment thereof, and a propagation material of the target useful plant. The plant propagation material is seedlings, rhizomes, seedlings, cuttings or seeds.

A method for protecting crops from pests, comprising cropping the pesticidal composition with the first active ingredient flufenicol and the second active ingredient fenthrin with the target useful plant, the target pest or its environment, The target is in contact with the propagation material of the plant.

A method for protecting crops against pest infestation comprises separately, sequentially or simultaneously administering a first active ingredient, flupirizine, and a second active ingredient, fenthrin.

A method of preventing or controlling a pest, wherein each of the first active ingredient flupirizine and the second active ingredient fenthrin is in the form of a formulated composition.

A method of protecting a plant seed comprising contacting the seed with an effective amount of the pesticidal composition of the present invention prior to sowing and/or after germination.

A seed treated with the pesticidal composition of the present invention.

The present inventors have found that combining the first active ingredient flufenicol and the second active ingredient, cyprofen, not only provides an additive effect on the insecticidal spectrum, but also achieves a surprising synergistic effect.

The term "synergistic effect" as used herein means that the insecticidal effect of the active ingredient combination of the present invention is greater than the sum of the effects of the respective active ingredients, or that the effect is superadditive.

The present invention provides a pesticidal composition comprising a first active ingredient, fipronil, and a second active ingredient, etofen.

The present invention provides a pesticidal composition, wherein the first active ingredient flufenicol and the second active ingredient fenthrin have a weight ratio of 1:100-100:1, preferably 1:50-50:1, It is preferably 1:25 to 25:1, more preferably 1:10 to 10:1.

The total amount of active ingredient in the compositions of the invention can be selected based on the particular factors to achieve the desired effect. The factors are, for example, a dosage form, a subject to be administered, an administration method, and the like. The first active ingredient, fipronil and the second active ingredient, etofenprox, together comprise from 5% to 90%, preferably from 10% to 80%, more preferably from 20% to 60% by weight of the composition.

The compositions of the present invention may optionally comprise an agronomically acceptable surfactant and/or extender.

According to the invention, the term "filler" refers to a natural or synthetic organic or inorganic compound which may be combined or combined with the active ingredient to make it easier to apply to a subject, such as a plant, crop or grass. Therefore, the filler is preferably inert and at least agriculturally acceptable. The filler may be a solid or a liquid.

Suitable solid carriers are: for example, vegetable powders (eg soy flour, starch, cereal flour, wood flour, bark flour, sawdust, walnut shell flour, bran, cellulose powder, coconut shell, corn cob and tobacco stem) Granules, residues after extracting plant extracts, etc.), clays (such as kaolin, bentonite, acid china clay, etc.), talc. Silica (such as diatomaceous earth, silica sand, mica, hydrous silicic acid, calcium silicate), activated carbon, natural minerals (pumice, attapulgite and zeolite), fired diatomaceous earth, sand, plastic media, etc. (for example, polyethylene, polypropylene, polyvinylidene chloride, etc.), inorganic mineral powders such as potassium chloride, calcium carbonate, and calcium phosphate, chemical fertilizers such as ammonium sulfate, ammonium phosphate, urea, and green ammonium, and soil fertilizers. The substances may be used singly or in combination of two or more.

Suitable liquid carriers can be selected from the group consisting of water, alcohols (eg methanol, ethanol, isopropanol, butanol, ethylene glycol, etc.), ketones (eg acetone, methyl ethyl ketone, diisobutyl) Ketones, cyclohexanone, etc.), ethers (such as diethyl ether, dioxane, methylcellulose, tetrahydrofuran, etc.), aliphatic hydrocarbons (such as kerosene, mineral oil, etc.), aromatic hydrocarbons (for example) Benzene, toluene, xylene, mineral spirits, alkylnaphthalenes, chlorinated aromatic hydrocarbons, chlorinated aliphatic hydrocarbons, chlorobenzene, etc.), halogenated hydrocarbons, amides, sulfones, dimethyl sulfoxide, minerals and vegetable oils, Animal oil, etc.

The compositions of the present invention may also comprise additional additional components such as surfactants. Suitable surfactants are emulsifiers, dispersants or wetting agents having ionic or nonionic properties, or mixtures of these surfactants. Suitable of these surfactants are fatty alcohol polyoxyethylene ethers, polyoxyethylene alkyl aryl ethers, polyoxyethylene higher fatty acid esters, Phosphate of polyoxyethylene alcohol or phenol, fatty acid ester of polyhydric alcohol, sodium alkylaryl sulfonate, naphthalenesulfonic acid polymer, lignosulfonate, polymer comb-shaped copolymer, butyl naphthalene An acid salt, an alkyl aryl sulfonate, an alkyl sulfosuccinate, a fat or oil, a polycondensate such as a fatty alcohol and an ethylene oxide condensate, an alkyl taurate, or a protein hydrolyzate. Suitable oligosaccharides or polymers are for example based on the individual ethylene monomers, acrylic acid, polyoxyethylene or polyoxypropylene or their combination with, for example, (poly)alcohols or (poly)amines. When one of the active compounds and/or one of the inert carriers is insoluble in water and when applied in water, a surfactant must be present. The proportion of surfactant is from 5% to 40% by weight of the composition of the invention.

If appropriate, other additional components may also be present, such as disintegrants, thickeners, antifreeze agents, antifoaming agents, stabilizers, protective colloids, binders, adhesives, thixotropic agents, penetrants, stabilizers, masking agents. Agent, sequestering agent, complex forming agent. In general, the active compound can be combined with any solid or liquid additive conventionally used for formulation purposes.

The disintegrating agent is selected from one or more of sodium hydrogencarbonate, sodium carbonate, bentonite, urea, ammonium sulfate, glucose, and aluminum chloride.

The thickener is selected from the group consisting of: hydroxymethyl cellulose, hydroxyethyl cellulose, aluminum magnesium silicate, gelatin, guar gum, gum arabic, xanthan gum, sodium tripolyphosphate, phenolic resin, sodium alginate, One or more of white dextrin, methyl cellulose, sodium acrylate, polyvinyl pyrrolidone, crosslinked polyvinylpyrrolidone, polyethylene glycol, and polyvinyl alcohol.

The antifreeze agent is selected from one or more of glycerin, ethylene glycol, propylene glycol, glycerol, diethylene glycol, triethylene glycol, and polyethylene glycol.

The antifoaming agent is selected from one or more of the group consisting of silicones, C _8-10 fatty alcohols, C _10-20 saturated fatty acids and amides, silicone oils, and silicone compounds.

The stabilizer is selected from the group consisting of: BHT, triphenyl phosphite, epichlorohydrin, organic acid, organic base, ester, alcohol, antioxidant, surfactant, tributyl phosphate, triethanolamine, two One or more of ethanolamine and ethanolamine.

The preparation of the present invention may be mixed with the active ingredient in a known manner by at least one of a solvent or a diluent, an emulsifier, a dispersing agent, and/or a binder or a fixing agent, and wetting. The agent, the water repellent, and if necessary, may also contain a drier and a colorant, a stabilizer, a pigment, an antifoaming agent, a preservative, a thickener, water, and other processing aids.

The pesticidal compositions of the present invention may be used as such or may be used in the form of their formulations or in the form in which they are prepared, depending on their respective physical and/or chemical properties. An example of a dosage form for a premix composition is:

GR: granules

WP: wettable powder

SP: Soluble powder

WG: water dispersible granules

SG: soluble granules

SL: solution

EC: EC

EW: emulsion, water emulsion

ME: Microemulsion

SC: Suspending agent

CS: microcapsule suspension

OD: oil-based suspension

SE: suspoemulsion

FS: seed coating agent

Examples of dosage forms suitable for tank mix compositions are solutions, diluted emulsions, suspensions or mixtures and powders thereof. Typically, the tank mix composition is one or more premix compositions containing different pesticides, and optionally further auxiliaries, diluted with a solvent such as water.

The compositions of the present invention include not only ready-to-use compositions that can be applied to plants or seeds by suitable means, but also commercially available concentrates that must be diluted with water prior to administration.

The compositions of the present invention may also be administered in combination with other active ingredients such as fungicides, bactericides, attractants, insecticides, acaricides, nematicides, growth regulators, herbicides, Safety agents, fertilizers or chemical pheromones.

The pesticidal composition of the present invention has good plant compatibility and favorable constant temperature animal toxicity, and is suitable for controlling pests, especially insects, encountered in agriculture, forestry, storage products and materials, and sanitary fields. They are active against normally sensitive and resistant species and are active for all or a single developmental stage.

The term "pest" as used herein refers to any organism that can cause damage to the normal state of the plant. include:

Lepidopteran pests include, for example, chilosuppressalis (walker), Tryporyzaincertulas (walker), cnaphalocrocismedinalis Guenee, hellullaundalis, conogethespunctiferlis, mandarin Papilioxuthus, Pierisrapae crucivora, parnaraguttata, malacosoma Neustria testacea, lymantriadispar, hyphantriacunea, euproctissubflava, black Specimens motra (scopelodescontracus), Helicoverpaarmigera, Pink bollworm, trichoplusiani, mamestrabrassicae, spodopteraexigua, oblique Spodopteralitura, adoxophyesoranafasciata, adocophyeshonmai, arpixfuscocureanus, homonamagnanima, plutellaxylotella, pectinophoragossypiella.

Coleoptera pests include, for example, sitphilusoryzaelinne, Podagricomela nigricollis Che, S. zeamails, S. granarius, Cabbageleafbeetle, and small leafhoppers. (Daikon leaf beele), fleabeetle, Altica chalybea, phyllotretastriolata, Epitrixcucumeris, Ehirtipennis, E. fuscula, Aulacophoraindica (Gemlin), Phaedon cochleariae, etc.

Diptera pests include, for example, agromyzaoryzae, hydrelliagriseola, liriomyzatrifolii, chromatomyiahorticola, liriomyzabryoniae, gray fly (deliaplatura), deliaantiqua, ceratitiscapiatawiedgman, rhagoletispomonella, R. cingulata.

Hemipteran pests include, for example, megacoptapunctatissimum, eurydemarugosum, eysarcorislewisi, eysarcorisparvus, nezaraviridula, plautiastali, sylvestris Halymorphamista, cletuspunctiger, leptocorisachinensis, stephantispyrioides, and trigonotyluscoelestialium.

Homopteran pests include, for example, nephotettixcincticeps, laodelphaxstriatellus, nilaparvatalugens, sogatella furcifera, psyllapyrisuga, diaphorinatabaci, and tobacco powder Be (bemisiatabaci), locust (homoptera), apple aphid (eriosomalanigerum).

Among the hymenoptera, there are arachinasaefifinis, argepagana, formica japonica, and dryocsmuskuriphilus.

Thysanoptera pests such as Haplothrips Chinensis Priesner.

Arachnida pest. For example, panonychus citri, Tetranychus cinnabarinus, panonychus ulmi, tetranychus urticae, tetranychus viennensis, and small needles Oligonychus ununguis) eotetranychus kankitus, brevipalus phoenicis, bryobia praetiosa, aceria tulipae, colomerus vitis, calacarus Carinatus), polyphagotarsonemus latus, rhizoglyphus rostochiensis, and the like.

Anoplura (Phthiraptera), such as the genus Damalinia spp., blood genus (Haematopinus spp.), genus Linognathus spp., Pediculus spp., Trichodectes spp.

Isopoda, for example, Oniscus asellus, Armadilliudium vulgare, Porcellio scaber.

Diplopoda, for example, Blaniulus guttulatus.

Chi lopoda, for example, Geophilus carpophagus Scutigera spp.

Synphyla, for example, Scutigerella immaculata.

Thysanura, for example, Lepisma saccharina.

Collembola, for example, the armed spiny worm (Onychiurus armatus).

Orthoptera, for example, Acheta domesticus, Gryllotalpa spp., Locusta migratoriamigrator ioides, Melanoplus pp., Desert 蝗 (Schistocercagregaria) ).

From the order of the Blattaria, for example, Blattorientalis, Periplaneta americana, Leucophaea maderae, Blattella germanica.

Dermaptera, for example, Forficula auricularia.

Isoptera (lsoptera), for example, Reticulitermes spp.

Representative organisms of Nematoda have nematodes selected from root-knot nematodes, cyst-forming nematodes, stem nematodes, and leaf nematodes. The following nematode soybeans, Heterodera, golbodera rostochiensis, melonogyne incognita, etc., in the dorylaimida, longidorus sp., and the like are preferred.

Preferably, the insecticidal composition is used for controlling rice planthopper, thrips, whitefly, aphids, brown crickets, white-backed planthoppers, black-tailed spider mites, cotton bollworms, red bollworms, peach aphids, melons , whitefly, cabbage caterpillar, tea caterpillar, tea mites, tea thorn moth, small heartworm, citrus leaf miner, tobacco nocturnal moth, diamondback moth, corn borer, big cockroach, heartworm.

The meaning of the plants herein is to be understood as meaning all plants and plant populations. Plants are plants obtainable by conventional breeding and preferred methods or by biotechnological and genetic engineering methods or by a combination of these methods. The plants include transgenic plants, as well as plant varieties that are protected or unprotected by plant breeders' rights. The meaning of a plant part is understood to mean all parts and organs of the plant above and below the ground, such as branches, leaves, flowers and roots, examples of which may be leaves, needles, leaves, stems, stems, flowers, fruit bodies, fruits. And seeds, as well as roots, tubers and rhizomes. The plant parts also include harvested material as well as vegetative and generative propagation material such as cuttings, tubers, rhizomes, young shoots and seeds.

Useful plants that can be used in the protection of the present invention, as well as the application of the pesticidal composition according to the present invention, include: cereal plants Such as wheat, oats, barley, triticale and rye, as well as corn, sorghum and chestnut, rice; sugar beets, such as sugar beets or fodder beets; fruits such as apple fruits, stone fruits, tree nuts or soft fruits, such as apples, Pears, plums, peaches, bananas, almonds, walnuts, pistachios, cherries or berries, such as strawberries or blackberries; legumes such as kidney beans, peas or soybeans; oil crops such as canola, mustard, olives, sunflowers, ramie, Cocoa or peanut; Cucurbitaceae, such as pumpkin, zucchini, cucumber or melon; fiber plants such as cotton, flax, hemp or jute; citrus fruits such as oranges, lemons, grapefruits or oranges; vegetables such as spinach, lettuce, Asparagus, cabbage, carrots, onions, tomatoes, red peppers, potatoes or bell peppers; medlars such as avocados, cinnamon or camphor; and tobacco, nuts, coffee, eggplant, sugar cane, tea, pepper, vines, hops, cars Forageaceae, gum-producing plants, lawns, lawns, forage grasses, and ornamental plants such as petunia, pansy, and balsam; and shrubs and broad Trees and evergreen plants such as conifers.

The present invention provides a method for preventing or controlling a pest, which comprises applying the pesticidal composition of the present invention to a target useful plant, a target pest or an environment thereof, and a propagation material of the target useful plant.

The treatment of plants and plant parts with the compositions of the invention is carried out directly by conventional treatment or by acting on their environment, habitat or storage area, such as impregnation, watering, spraying, misting, spreading, Spraying, fogging, spreading, foaming, coating, coating, drip irrigation, etc. to the leaves of plants (foliar application), the frequency and amount of application can be adjusted to adapt to the extent of damage by the pests .

According to the invention, all plants and plant parts can be treated. Plants are understood herein to mean all plants and plant communities, such as desirable and undesirable wild plants or crops (including naturally occurring crops). The crop may be a plant obtained by conventional propagation and optimization methods or by biotechnological and genetic engineering methods or by a combination of these methods, including transgenic plants, and includes plant varieties that may or may not be protected by plant variety protection laws. Plant parts are understood to mean all above-ground and underground parts and organs of plants, such as shoots, leaves, flowers and roots, such as leaves, needles, stems, branches, flowers, fruiting bodies, fruits and seeds, and roots. , tubers and rhizomes. Plant parts also include harvested and asexual and sexually propagated materials such as seedlings, tubers, rhizomes, cuttings, and seeds.

The compositions of the invention are also suitable for protecting plant propagation material such as seeds, fruits, tubers or nucleoli or plant cuttings from pests, particularly insects and mites. The propagation material can be treated with the composition prior to application, such as seed dressing prior to sowing. The active ingredient can also be applied to the seed (coating) by soaking the nucleoli in the liquid composition or coating the nucleolus with a solid composition. The composition can also be applied to the application site when the propagation material is applied, for example, within the seed ditch during sowing. These methods of treating plant propagation materials and plant propagation materials so treated are further subject matter of the present invention.

The term "plant propagation material" is understood to mean all parts of the plant capable of reproduction, such as seeds, as well as plant material such as cuttings or tubers (for example potatoes). Thus, the plant parts used herein include plant propagation material. Mention may be made, for example, of seeds (in the narrow sense), roots, fruits, tubers, bulbs, rhizomes and plant parts. Waiting Germinated plants and effective plants which are inhibited after germination in the soil or after emergence are also mentioned. Young plants can be protected by whole or partial treatment by dipping prior to transplantation.

Plant parts and subsequently grown plant organs are any part of a plant produced by plant propagation material such as seeds. Plant parts, plant organs and plants can also benefit from protecting plants from plant diseases by applying the compositions to plant propagation materials. Certain plant parts and certain subsequently grown plant organs can also be considered as plant propagation material, which can itself be applied (or treated) with the composition; thus plants produced from treated plant parts and treated plant organs, Other plant parts and other plant parts may also benefit from protecting the plant from plant pests by applying the composition to certain plant parts and certain plant organs.

For the treatment of plant propagation material, in particular seeds, the active ingredient can also be applied to the seed by successively impregnating the tubers or grains with a liquid preparation of the respective active ingredients, or by coating with a combined wet or dry preparation (coating) ).

The compositions of the invention are applied to the seed in their own right or in a suitable dosage form. Preferably, the seed is treated in a steady state such that the treatment does not cause any damage. The treatment of the seed can usually be carried out at any time between harvesting and sowing. It must generally be noted during seed treatment that the amount of the composition of the invention applied to the seed and/or the amount of other additives is selected so as not to affect the germination of the seed or to damage the resulting plant.

The compositions of the present invention are particularly advantageous for treating plant propagation material, particularly seeds of rice, canola, cotton, wheat, barley, soybean, corn, peanuts.

A method of protecting a seed comprising contacting the seed with a synergistically effective amount of a pesticidal composition of the present invention prior to sowing and/or after germination.

A seed treated with the pesticidal composition of the present invention.

The compositions of the invention can be applied to the environment, habitat or storage area in which the plants are grown. The environment and habitat of plant growth refer to a support capable of rooting and growing crops, such as soil, water, etc. Specific raw materials can be used, for example, sand, pumice, vermiculite, diatomaceous earth, agar, gelatin, High molecular substances, asbestos, wood chips, bark, etc. Soil is preferred.

A method of applying a medicament to the soil, for example, diluting the liquid medicament in water or undiluting the root applied directly to the root of the plant or the method of growing the farm, and spreading the granule into the root of the plant or in the field of the nursery Before spraying, powder, water-dispersible granules, etc. are sprayed into the soil and mixed with the soil as a whole. Before the planting or planting the object, the powder and the water-dispersible granules are diluted and sprayed in the planting hole and the seeding ditch. The method of sowing, etc.

On the other hand, the treatment of the present invention may also produce a super-additive effect of improving plant growth, increasing tolerance to high or low temperatures, increasing tolerance to drought or salinity to water or soil, and increasing flowering. Quality, ease of harvesting, accelerated maturity, improved harvesting yield, improved quality of harvested products and/or improved nutritional value, improved storage stability of harvested products and/or their processing properties.

It is common and advantageous for the pesticidal compositions of the invention to be administered at the following dosages:

- for foliar treatment: 0.1-10000 g/ha, preferably 10-1000 g/ha, more preferably 20-300 g/ha; for dipping or drip application, the dose can even be reduced, in particular when applying an inert matrix When it is asbestos or pearl rock;

- for seed treatment: 2-200 g / 100 kg seed, preferably 3-150 g / 100 kg seed;

- For soil treatment: 0.1-10000 g/ha, preferably 1-5000 g/ha.

The above dosages are merely exemplary exemplary dosages, and those skilled in the art will adjust the application rate according to actual conditions and needs, especially depending on the nature of the plants or crops to be treated and the pest conditions.

The pesticidal composition of the present invention comprises the separate, sequential or simultaneous administration of the first active ingredient flupirizine and the second active ingredient, fenthrin.

It should be noted that any of the technical features of any embodiment or embodiment of the present invention may be independently combined with any other embodiment of the present invention. That is, one or more of the technical features of any of the embodiments of the present invention can be recombined with any other technical features. Technical features formed by recombining such technical features are disclosed herein, as specifically recited herein.

The benefits of the present invention by combining the two are as follows:

A. The synergistic effect on pests is obvious, which can reduce the dosage of the two components;

B. The combination of the two solves the problem of pest persistence period and quick-acting effect, thereby reducing the number of medications and reducing labor costs;

C. Delaying the generation of resistance: the mechanism and mode of action of the two are completely different, which makes the pests more likely to be killed, thereby delaying the generation of resistance;

D. Expanded the spectrum of prevention and treatment.

detailed description

The invention will be further illustrated by the following examples.

Formulation example

Example 1 Emulsifiable Oil

Flubenacetin	2%
		Ethylmethrin	3%
Ethylene glycol monomethyl ether	20%
		Ethoxylated castor oil	4%
Fatty alcohol polyoxyethylene ether sulfosuccinate monosodium disodium	10
		N-methylpyrrolidone	Make up to 100%

The above-mentioned components are mixed and stirred to a uniformly transparent liquid to obtain the emulsifiable concentrate of the present invention.

Example 2 wettable powder

Flubenacetin

10%

Ethylmethrin	10%
		Sodium dodecyl sulfate	2%
Sodium lignosulfonate	5%
		Sodium sulfate	5%
White carbon black	10%
		Kaolin	Make up to 100%

The wettable powder of the present invention is obtained by mixing the active ingredients, various auxiliaries, fillers and the like in proportions of the formulation and pulverizing them by an ultrafine pulverizer.

Example 3 water emulsion

Flubenacetin	10%
		Ethylmethrin	2%
Cyclohexanone	15%
		Sodium dodecyl benzene sulfonate	5%
Phenylethyl phenol polyoxyethylene ether	5%
		water	Make up to 100%

The original drug, the solvent and the emulsifier are added together to dissolve into a uniform oil phase; the water-soluble component and water are mixed to prepare an aqueous phase; and the oil phase is mixed with the water phase under high-speed stirring to obtain the present invention. Water emulsion.

Example 4 Water Dispersible Granules

Flubenacetin	50%
		Ethylmethrin	10%
Sodium lignosulfonate	5%
		Sodium dodecyl sulfate	2%
Urea	10%
		Kaolin	Make up to 100%

The active ingredient, the dispersing agent, the wetting agent, the disintegrating agent and the filler are uniformly mixed according to the formulation ratio, and are pulverized into a wettable powder by a jet stream, and then added with a certain amount of water to be mixed and granulated. The water-dispersible granules of the present invention are obtained by dry sieving.

Example 5 microemulsion

Flubenacetin	10%
		Ethylmethrin	50%
N-methylpyrrolidone	20%
		Ethoxylated castor oil	5%
Fatty alcohol polyoxyethylene ether sulfosuccinate monosodium disodium	5%
		water	Make up to 100%

The microemulsion of the present invention is obtained by mixing and stirring the above components to a uniformly transparent liquid.

Example 6 wettable powder

Flubenacetin	50%
		Ethylmethrin	1%
Sodium dodecyl sulfate	10%
		Sodium lignosulfonate	15%
Silicone oil	1%
		Sodium sulfate	5%
White carbon black	10%
		Kaolin	Make up to 100%

The wettable powder of the present invention is obtained by mixing the active ingredients, various auxiliaries, fillers and the like in proportions of the formulation and pulverizing them by an ultrafine pulverizer.

Example 7 suspoemulsion

Flubenacetin	2%
		Ethylmethrin	50%
SOLVESSO TM 200	10%
		Ethoxylated castor oil	4%
Fatty alcohol polyoxyethylene ether sulfosuccinate monosodium disodium	10%
		Modified calcium lignosulfonate	5%
Xanthan gum	0.5%
		Bentonite	1%
Glycerol	5%
		Defoamer	0.6%
water	Make up to 100%

Dissolving the second active ingredient, fenthrin, in SOLVESSO ^TM 200, adding ethoxylated castor oil to obtain emulsifiable concentrate; and first active ingredient flufenicol, fatty alcohol polyoxyethylene ether sulfosuccinate monosodium disodium The modified components such as calcium lignosulfonate, xanthan gum, bentonite, glycerin, water, etc. are uniformly mixed in proportion and sand-milled to prepare a suspension. An oil phase containing the first active ingredient flupirrazil is added to a suspension containing the second active ingredient, methrin, to obtain a suspoemulsion.

Example 8 water emulsion

Oil phase:

Flubenacetin	1%
		Ethylmethrin	10%
Methyl oleate	10%
		Polystyrene	3.7%

water box:

Xanthan gum

0.07%

Sodium salt of sulfonated naphthalenesulfonic acid-formaldehyde condensation product	1%
		Fungicide	0.2%
water	Make up to 100%

Dissolving the first active ingredient, flufenicol and the second active ingredient, ethyl ester, in methyl oleate, adding polystyrene to obtain an oil phase; mixing the components according to the formula to obtain an aqueous phase; and stirring the oil The phase is added to the aqueous phase to obtain an aqueous emulsion.

Example 9 wettable powder

Flubenacetin	70%
		Ethylmethrin	20%
Sodium lignosulfonate	7%
		Sodium lauryl sulfate	2%
Kaolin	Make up to 100%

The above combinations are mixed in proportion, ground, and pulverized to prepare a wettable powder.

Example 10 coated granules

Flubenacetin	30%
		Ethylmethrin	50%
Polyethylene glycol	3%
		Highly dispersed silicic acid	1%
Calcium carbonate	Make up to 100%

The milled active ingredient is uniformly applied to the carrier wetted with polyethylene glycol in a mixer. In this way, dust-free coated granules can be obtained.

Example 11 wettable powder

Flubenacetin	5%
		Ethylmethrin	25%
Sodium lignosulfonate	10%
		Sodium dodecyl sulfate	3%
White carbon black	5%
		Kaolin	Make up to 100%

The above components are mixed in proportion, ground and pulverized to prepare a wettable powder.

Example 12 extruded granules

Flubenacetin	1%
		Ethylmethrin	50%
Sodium lignosulfonate	4%
		Carboxymethyl cellulose	2%
Kaolin	Make up to 100%

The active ingredient is mixed with the auxiliaries and ground and the mixture is moistened with water. The mixture was extruded and then dried in a stream of air.

Example 13 suspoemulsion

Flubenacetin	20%
		Ethylmethrin	2%
SOLVESSO TM 200	10%
		Ethoxylated castor oil	4%
Fatty alcohol polyoxyethylene ether sulfosuccinate monosodium disodium	10%
		Modified calcium lignosulfonate	5%
Xanthan gum	0.5%
		Bentonite	1%
Glycerol	5%
		Defoamer	0.6%
water	Make up to 100%

Dissolving the second active ingredient, ethyl chrysanthemum, in SOLVESSO ^TM 200, adding ethoxylated castor oil to obtain an emulsifiable concentrate; and adding a second active ingredient, cyproterol, a fatty alcohol polyoxyethylene ether sulfosuccinate monosodium disodium, The above components of the modified calcium lignin sulfonate, xanthan gum, bentonite, glycerin, water, etc. are uniformly mixed in proportion and sand-milled to prepare a suspension agent. An oil phase containing the second active ingredient, etofenproxil, is added to a suspension containing the first active ingredient, flubenzuron, to obtain a suspoemulsion.

Example 14 suspoemulsion

Flubenacetin	25%
		Ethylmethrin	25%
SOLVESSO TM 200	10%
		Ethoxylated castor oil	4%
Fatty alcohol polyoxyethylene ether sulfosuccinate monosodium disodium	10%
		Modified calcium lignosulfonate	5%
Xanthan gum	0.5%
		Bentonite	1%
Glycerol	5%
		Defoamer	0.6%
water	Make up to 100%

Dissolving the second active ingredient, ethyl chrysanthemum, in SOLVESSO ^TM 200, adding ethoxylated castor oil to obtain the second active ingredient, ethreate emulsifiable concentrate; the first active ingredient, flufenicol, fatty alcohol polyoxyethylene ether The sulfosuccinate monosodium disodium, modified lignosulfonate calcium, xanthan gum, bentonite, glycerol, water and the like are uniformly mixed in proportion and sand-milled to prepare a suspension. An oil phase containing the second active ingredient, etofenproxil, is added to a suspension containing the first active ingredient, flubenzuron, to obtain a suspoemulsion.

Example 15 suspoemulsion

Flubenacetin	50%
		Ethylmethrin	2%
SOLVESSO TM 200	10%
		Ethoxylated castor oil	4%
Fatty alcohol polyoxyethylene ether sulfosuccinate monosodium disodium	10%
		Modified calcium lignosulfonate	5%
Xanthan gum	0.5%
		Bentonite	1%
Glycerol	5%
		Defoamer	0.6%
water	Make up to 100%

Dissolving the second active ingredient, ethyl chrysanthemum, in SOLVESSO ^TM 200, adding ethoxylated castor oil to obtain the second active ingredient, ethreate emulsifiable concentrate; the first active ingredient, flufenicol, fatty alcohol polyoxyethylene ether The sulfosuccinate monosodium disodium, modified lignosulfonate calcium, xanthan gum, bentonite, glycerol, water and the like are uniformly mixed in proportion and sand-milled to prepare a suspension.

The oil phase containing the second active ingredient, etofenproxil, is added to a suspension containing the first active ingredient, flubenzuron, to obtain a suspoemulsion.

Example 16 emulsifiable concentrate

Flubenacetin	5%
		Ethylmethrin	15%
Xylene mixture	20%
		Ethoxylated castor oil	4%
Fatty alcohol polyoxyethylene ether sulfosuccinate monosodium disodium	10
		SOLVESSO TM 200	Make up to 100%

The above components are mixed and stirred to a uniformly transparent liquid to obtain the emulsifiable concentrate of the present invention.

Example 17 Microcapsule Suspension-Suspending Agent

ATLOX TM 4913	4%
		Citric acid	0.05%
catalyst	0.1%
		water	13%
Ethylmethrin	5%

PAPI	1.35%
		SOLVESSO TM 200	10%
ATLOX TM 4913	16%
		Dispersant LFH	0.3%
Defoamer	0.16%
		Urea	8.4%
Flubenacetin	25%
		water	Make up to 100%

The plurality polymethylene polyphenyl polyisocyanate (the PAPI), and a second active ingredient Etofenprox SOLVESSO ^TM 200 oil was added an aqueous solution containing phase formed in ATLOX ^TM 4913, to form an emulsion. The catalyst was then heated and kept warm at 50 ° C for 2 hours. After cooling, a microcapsule containing the second active ingredient, efenthrin, is obtained.

ATLOX ^TM 4913, dispersant LFH, antifoaming agent, urea, the first active ingredient flufenicol and water are uniformly mixed in proportion and sanded to prepare a suspension.

The obtained microcapsule containing the second active ingredient permethrin is added to the aqueous suspension of the first active ingredient flupirtine, and stirred uniformly to obtain the microcapsule suspension-suspending agent of the present invention.

Example 18 suspension seed coating agent

Flubenacetin	5%
		Ethylmethrin	50%
SOLVESSO TM 200	20%
		Ethoxylated castor oil	5%
Fatty alcohol polyoxyethylene ether sulfosuccinate monosodium disodium	10%
		Modified sodium lignosulfonate	5%
Xanthan gum	0.5%
		Glycerol	5%
Polyvinylpyrrolidone (PVP-K30)	1%
		Defoamer	0.6%
water	Make up to 100%

Dissolving the second active ingredient, fenthrin, in SOLVESSO ^TM 200, adding ethoxylated castor oil to obtain an emulsifiable concentrate containing the second active ingredient fenthrin; and the first active ingredient flufenicol, a fatty alcohol polyoxyethylene Ether sulfosuccinate monosodium disodium, modified lignosulfonate calcium, xanthan gum, glycerol, polyvinylpyrrolidone, water, etc. The above components are uniformly mixed in proportion and sand-milled to prepare a suspension agent .

The oil phase containing the second active ingredient methrin is added to the suspension seed coating containing the first active ingredient flupirizine to obtain the suspension seed coating of the present invention.

Example 19 aerosol

Flubenacetin	5%
		Ethylmethrin	5%
Propylene glycol	5%

Phosphate	3.5%
		Ethoxylated castor oil	2.0%
SOLVESSO TM 100	Make up to 100%

First, the antifreeze propylene glycol, the diluent SOLVESSO ^TM 100 is mixed, and the first active ingredient flufenicol and the second active ingredient fenthrin are added under stirring; the surfactant is added thereto, and the mixture is stirred by a pulverizing equipment colloid mill. After pulverization, the colloid-milled suspension is passed through an ultrafine pulverizer. The cycle is repeated until the particle diameter of the solid particles is ≤ 2 um.

Example 20 wettable powder

Flubenacetin	50%
		Ethylmethrin	5%
Sodium dodecyl sulfate	1%
		Sodium lignosulfonate	1%
White carbon black	1%
		Kaolin	Make up to 100%

The wettable powder of the present invention is obtained by mixing the active ingredients, various auxiliaries, fillers and the like in proportions of the formulation and pulverizing them by an ultrafine pulverizer.

Example 21: Oil Suspension

The components of the active component, the dispersing agent and the wetting agent are uniformly mixed according to the formulation ratio, and after grinding and/or high-speed shearing, corn oil is added to obtain an oil suspensioning agent.

Example 22 powder

Flumazepam 10%

Ethyl pyrethrin 20%

Talc powder is made up to 100%.

Example 23 Active ingredient conjugate

Flubenacetin	10%
		Ethylmethrin	90%

The first active ingredient flufenicol and the second active ingredient, etofenthrin, are uniformly mixed in proportion.

The ratio in the above embodiment is a weight ratio of one hundred.

Biological test case

Combining the active ingredients of different pesticides into pesticides is an effective and quick way to develop and develop new pesticides and to control agriculturally resistant pests. After mixing different pesticides, they usually show three types of action: additive, synergistic and antagonistic. However, the specific role is unpredictable and can only be known through a large number of experiments. The formula with good synergistic effect has obviously improved the actual control effect and reduced the use of pesticides, thus greatly delaying the speed of pest resistance, and is an important means for comprehensive prevention and control of pests.

The inventors conducted a large number of tests and effect analysis on the different ratios of flubenzuron and fenthrin through a large number of screening tests, and found that the new compound insecticide obtained has a gain within a certain ratio range. The effect, not just the simple addition of the two agents, is specifically illustrated by the following embodiments.

In the embodiment of the present invention, a combination of indoor virulence determination and insecticidal test is adopted, firstly, the indoor toxicity test is used to determine the co-toxicity coefficient (CTC) of the two agents after being compounded in a certain ratio, and CTC<80 is resistant. Antagonism, 80 ≤ CTC ≤ 120 for the additive effect, CTC > 120 for the synergistic effect, on this basis, the insecticidal test.

Test method: The compound pesticide reagents in the above examples were diluted into five series of concentrations, respectively, and placed in a beaker for use. Then, the leaves of the same size that have not been contacted with any agent are soaked in the prepared liquid for 5s, then taken out, naturally dried, placed in the insect box, and then the test larva is attached. Breeding at 25 °C, each treatment was repeated 3 times, the number of test insects used per repetition was 20, and a blank control was set at the same time. The number of dead insects was checked at 72 hours, the mortality and corrected mortality were calculated, and the virulence regression equation was obtained. And calculate the LC ₅₀ value. If the control mortality is greater than 10%, it is considered an invalid test. Calculated as follows:

Mortality (%) = (number of live insects before drug - number of live insects) / number of live insects before drug *100

Corrected mortality (%) = (treatment group mortality - control group mortality) / (100 - control group mortality) * 100

The test insect corrected mortality rate was converted into probability value (y), the treatment concentration (μg/ml) was converted into logarithmic value (x), and the virulence regression equation was obtained by least squares method, and thus each medicament was calculated. value. According to the Sun Yunpei formula method, the co-toxicity coefficient CTC was calculated. The calculation formula is as follows (with flufenicol as a standard drug, its virulence index is 100):

Measured virulence index (ATI) = (standard drug LC ₅₀ / test agent LC ₅₀ ) × 100

Theoretical virulence index (TTI) = A ATI × percentage of A in the mixture + B ATI × percentage of B in the mixture

Co-toxicity coefficient (CTC) = (mixture ATI / mixture TTI) × 100

Test 1: Determination of indoor virulence of citrus aphids

Table 1

It can be seen from Table 1 that the co-toxicity coefficient of flufenicol and etofenprox in the range of 1:100-100:1 in the control of citrus aphids is greater than 120, indicating that the two are mixed in this range. It is characterized by a gain effect, especially when the ratio of the two is 1:10, the gain effect is particularly prominent.

Test 2: Results of indoor virulence test on beet armyworm

Table 2

It can be seen from Table 2 that flufenicol and fenthrin inhibit the beet armyworm, and the co-toxicity coefficient is greater than 120 in the range of 1:100-100:1, indicating that the two are mixed in this range. Both show a gain effect, especially when the ratio of the two is 1:10, the gain effect is particularly prominent.

In addition, according to the above virulence determination method, the indoor virulence test results of rice planthopper, thrips, whitefly, and spider mites also showed that flufenicol and efenthrin prevent rice planthopper, thrips, and tobacco. When the whitefly and leafhopper are in the range of 1:100-100:1, the co-toxicity coefficient is greater than 120, indicating that the mixing of the two in this range is a gain effect.

Control test

Synergistic insecticidal and acaricidal effects are present when the effect of the active compound composition exceeds the sum of the effects when the individual active compounds are applied separately. The expected effect of a particular combination of the two active compounds can be calculated using the so-called "Colby Formula" (see S. R. Colby, "Calculating Synergistic and Antagonistic Responses of Herbicide Combinations", Weeds 1967, 15, 20-22) as follows:

X is the kill rate when active compound A is used in an amount of m g/ha or at a concentration of m ppm, expressed as a percentage of the untreated control,

Y is the kill rate when using the active compound B in an amount of n g/ha or a concentration of n ppm, expressed as a percentage of the untreated control,

E is the killing rate when active ingredients A and B are used in amounts of m and n g/ha or at concentrations of m and n ppm, expressed as a percentage of the untreated control,

Then

If the actual insecticidal lethality exceeds the calculated value, the lethal effect of the composition is superadditive, i.e., there is a synergistic effect. In this case, the actually observed kill rate must exceed the value of the expected kill rate value (E) calculated using the above formula.

Trial 3: Efficacy test of citrus aphid

The test was carried out as follows: The test site was in Jiaxing, Zhejiang, and the time was in early March. The potted citrus test was carried out for 3 years. Before the spraying, 200 insects were inoculated with cotton aphid. Spray treatment 2 days after inoculation. According to the front and back of the wetted leaves, 3 citrus seedlings were treated each. Six days after the drug, 25 leaves were taken in the laboratory to investigate the number of adults on the leaves with binoculars, and the population reduction rate and control effect were calculated. The formula is as follows:

The specific test methods and data are as follows:

Insect mortality rate (%) = (number of live insects in the treatment area - number of live insects in the treatment area) / number of live insects in the treatment area *100 control effect (%) = (treatment area insect population reduction rate ± control area insect population Decrease rate) / (100 ± control area insect population reduction rate) * 100

table 3:

From the test results in Table 3, the control effect observed after the combination of flufenicol and etofenproxil was significantly higher than that of the calculated control effect, showing a significant synergistic effect.

Test 4: Efficacy test for controlling beet armyworm

The test was carried out as follows: The test site was in Jiaxing, Zhejiang, and the time was in early March. Potted cotton test was used. Before the spraying, 200 insects were inoculated into beet armyworms. Spray treatment 2 days after inoculation. According to the front and back of the wetted blade, each treatment of 3 cotton Strain. Six days after the drug, 25 leaves were taken in the laboratory to investigate the number of adults on the leaves with binoculars, and the population reduction rate and control effect were calculated. The formula is as follows:

The specific test methods and data are as follows:

Insect mortality rate (%) = (number of live insects in the treatment area - number of live insects in the treatment area) / number of live insects in the treatment area *100 control effect (%) = (treatment area insect population reduction rate ± control area insect population Decrease rate) / (100 ± control area insect population reduction rate) * 100

Table 4:

From the test results in Table 4, the control effect observed after the combination of flufenicol and fenthrin was significantly higher than the calculated control effect, showing a significant synergistic effect.

Experiment 5: Soil treatment on yellow stripe armor

Mixed soil 2: Sand 1: Rotating soil 1 Prepare experimental soil, 200 g of soil was placed in each 300 ml plastic container, and sprayed at a prescribed concentration of the drug. Ten larvae of yellow-striped fleas were placed in each container, and after standing at a constant temperature of 25 ° C in the dark, the soil was dispersed after the required time, and the number of larvae survived was counted to obtain mortality.

Mortality (%) = {1 - (number of survival heads / number of insects)} X100

The theoretical value (%) of mortality is calculated by the "colby formula". The test results show that the actual mortality rate (%) is higher than the theoretical value (%), indicating that the combination of flufenicol and etofenproxate, and the soil treatment has synergistic effect on the prevention and treatment of yellow stripe.

Test 6: Effect of seed treatment on beet armyworm

General method for liquid seed dressing F1:

The required amount of liquid formulation is added to the Erlenmeyer flask. Shake the flask to distribute the liquid to the entire bottom of the vessel. Immediately thereafter, the required amount of seeds is added to the bottle. The flask was shaken vigorously by hand for about 1 minute so that all the seeds were covered with liquid. The contents of the flask were poured onto a drying rack and dried in an oven.

General method of dry seed dressing F2:

The same number of kernels were loaded into each jar and a certain amount of solid preparation was filled in each vial to obtain The required amount of 0.3 mg of active ingredient per seed. The flask was placed on a roller and spun at 80 rpm for 3 minutes. The flask was shaken by hand to cause the seed sticking to the wall of the flask to fall, and then the flask was rotated in the opposite direction for 3 minutes.

The agent and the single agent of Formulation Example 1-22 were subjected to seed treatment at a prescribed concentration according to Procedures F1 and F2. The treated corn seeds are then sown. Twenty-six days after sowing, the 5-8 cm long portion of the topmost leaf of the plant was placed in a glass beaker and infested with 10 newly hatched beet armyworm first instar larvae. The beaker was covered with a lid and kept at 25 ° C and 60% relative atmospheric humidity for 16 hours per day. Evaluation was performed after infestation 3-5. The mortality rate was recorded after recording the number of larvae that survived on the grown plants.

Mortality (%) = {1 - (number of survival heads / number of insects)} X100

The theoretical value (%) of mortality is calculated by the "colby formula". The test results show that the actual mortality rate (%) is higher than the theoretical value (%), indicating that the combination of flufenicol and etofenproxate is used for seed treatment and has synergistic effect on the control of beet armyworm.

In addition, through the above experimental methods, rice planthopper, hummer, whitefly, brown planthopper, whitebacked planthopper, black-tailed leafhopper, cotton bollworm, red bollworm, peach aphid, melon, whitefly, cabbage caterpillar, tea Caterpillars, tea mites, tea thorn moth, small heartworm, citrus leaf miner, tobacco nocturnal moth, diamondback moth, corn borer, big cockroach, heartworm and other pests were tested for efficacy, and it was concluded that flufenicol and ether fenthrin were compounded. After that, it showed obvious synergistic effect, with good persistence and quick-acting effect, and reduced the dosage of the two components.

Claims (19)

1. An insecticidal composition characterized by comprising a first active ingredient, flufenicol

   

   And the second active ingredient, methrin,

   

   The weight ratio of the first active ingredient fipronil and the second active ingredient, methrin, is from 1:100 to 100:1.
2. The pesticidal composition according to claim 1, characterized in that the weight ratio of the first active ingredient fipronil and the second active ingredient permethrin is from 1:50 to 50:1.
3. The pesticidal composition according to claim 1, characterized in that the weight ratio of the first active ingredient fipronil and the second active ingredient permethrin is from 1:25 to 25:1.
4. The pesticidal composition according to claim 1, characterized in that the weight ratio of the first active ingredient flufenicol and the second active ingredient methrin is from 1:10 to 10:1.
5. The pesticidal composition according to claim 1, wherein the first active ingredient flubenicol and the second active ingredient methrin are 5% to 90% by weight of the composition.
6. The pesticidal composition according to claim 1, wherein the first active ingredient flufenicol and the second active ingredient fenmethrin together comprise from 10% to 80% by weight of the composition.
7. The pesticidal composition according to claim 1, wherein the first active ingredient, fluprosin and the second active ingredient, fenthrin, together comprise from 20% to 60% by weight of the composition.
8. The pesticidal composition according to claim 1, further comprising a surfactant and/or a extender.
9. The pesticidal composition according to claim 1, wherein the dosage form is an emulsifiable concentrate, a suspending agent, a seed coating agent, Water-dispersible granules, wettable powders, suspoemulsions, extruded granules, coated granules, aerosols, aqueous emulsions, microcapsule suspensions, ultra low volume liquids, microcapsule suspension-suspending agents.
10. Use of the pesticidal composition of claim 1 for the prevention or control of pests.
11. A method for preventing or controlling a pest, which comprises using the pesticidal composition of claim 1 for a target useful plant, a target pest or an environment thereof, and a propagation material of a target useful plant.
12. A method for preventing or controlling pests according to claim 11, wherein the plant propagation material is a seedling, a rhizome, a seedling, a cutting or a seed.
13. A method of preventing or controlling a pest according to claim 11, wherein the pest is selected from the group consisting of insects.
14. A method for preventing or controlling pests according to claim 11, wherein the pest is selected from the group consisting of rice planthopper, hummer, whitefly, aphid, brown planthopper, whitebacked planthopper, and black-tailed leaf.蝉, cotton bollworm, red bollworm, peach aphid, melon, whitefly, cabbage caterpillar, tea caterpillar, tea mites, tea thorn moth, small heartworm, citrus leaf miner, tobacco nocturnal moth, diamondback moth, corn borer, large螟, heartworm.
15. A method for preventing or controlling pests according to claim 11, comprising the step of separately, sequentially or simultaneously applying the first active ingredient flufenicol and the second active ingredient fenthrin.
16. A method of preventing or controlling a pest according to claim 11, wherein each of the first active ingredient flufenicol and the second active ingredient estrate is in the form of a formulated composition.
17. A method for protecting a crop against pest infestation, comprising: a target material, a target pest or an environment thereof, a propagation material of the target useful plant, and a first active ingredient flufenicol and a second active ingredient The insecticidal composition of the fenthrin is contacted.
18. A method of protecting a plant seed, comprising: contacting the seed with an effective amount of the pesticidal composition of claim 1 prior to sowing and/or after germination.
19. A seed treated with the pesticidal composition of claim 1.