CN115804425A - Feed composition for killing pig intestinal parasitic diseases and preparation method thereof - Google Patents
Feed composition for killing pig intestinal parasitic diseases and preparation method thereof Download PDFInfo
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Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Abstract
The invention provides a feed composition for killing pig intestinal parasitic diseases, which comprises a feed and a tea saponin compound product; the mixing mass ratio of the tea saponin compound product to the feed is 50-1000 mg/kg; the tea saponin compound product comprises, by mass, 40-60% of tea saponin, 10-20% of a dried ginger extract, 10-20% of a garlic extract, 10-20% of a litsea cubeba extract and 3-5% of pepper essential oil. Compared with the prior art, the feed composition for killing the pig intestinal parasitic disease can improve the cure rate of the pig infected with the coccidiosis, improve the immunity of pigs, effectively improve the average daily gain of the piglets and reduce the toxic carrying amount of animal organisms, thereby ensuring the food safety.
Description
Technical Field
The invention relates to the technical field of pig breeding, in particular to a feed composition for killing pig intestinal parasitic diseases and a preparation method thereof.
Background
Porcine coccidiosis is a piglet digestive tract disease caused by Eimeria coccidiosis (Eimeria) and Isospora coccidiosis (Isospora), and has the main symptoms of diarrhea, emaciation and stunted development; the disease mainly harms piglets within 7-21 days of age, the incidence rate is up to 50-75%, and the death rate is about 35%.
With the development of large-scale and intensive pig industry, the pig coccidiosis in China brings up losses of 7 to 25 billion yuan to the pig industry every year. At present, the prevention and treatment method for the pig coccidiosis is mainly antibiotic injection treatment, and although the prevention and treatment method can play a certain role in preventing and treating the pig coccidiosis, along with the large-amount and long-term use of antibiotics, microorganisms in pigs generate a bad result of drug resistance, and further, the use of antibiotics with higher dose is caused, and the pig coccidiosis falls into a vicious circle. The antibiotic injection therapy is not only high in feeding cost, but also has adverse effects on the user due to the residual medicine in the pig body. Therefore, how to prevent and treat the swine coccidiosis in an efficient and safe manner becomes a big problem to be solved in the livestock husbandry industry.
Disclosure of Invention
The invention mainly aims to provide a feed composition for killing pig intestinal parasitic diseases and a preparation method thereof, and aims to solve the problems that the feed in the prior art is high in cost, and medicines remaining in a pig body can bring adverse effects to a user.
In order to achieve the purpose, the invention provides a feed composition for killing pig intestinal parasitic diseases, which comprises a feed and a tea saponin compound product; the tea saponin compound product and the feed are mixed according to the proportion of 50-1000 mg/kg; the tea saponin compound product comprises, by mass, 40-60% of tea saponin, 10-20% of a dried ginger extract, 10-20% of a garlic extract, 10-20% of a litsea cubeba extract and 3-5% of pepper essential oil.
Further, the mixing mass ratio of the tea saponin compound product to the feed is 300-600 mg/kg; the tea saponin compound product comprises, by mass, 48-55% of tea saponin, 12-18% of a dried ginger extract, 12-18% of a garlic extract, 12-18% of a litsea cubeba extract and 3-5% of pepper essential oil.
Furthermore, the feed comprises, by mass, 73-80% of cereal flour, 2-4% of saccharides, 0.6-1.1% of calcium hydrophosphate, 0.5-1.5% of amino acid, 1.5-5.1% of stone powder, 0.7-1.4% of vegetable oil, 0.6-1.1% of additive, 5.1-8.1% of fish meal, 1.9-4.1% of vegetable protein powder and 0.4-0.9% of salt.
Further, the feed comprises, by mass, 75-78% of cereal flour, 3-4% of saccharides, 0.8-1.0% of calcium hydrogen phosphate, 1.0-1.2% of amino acid, 2.8-4.0% of stone powder, 1.0-1.4% of vegetable oil, 0.8-1.0% of additive, 6.5-8.0 of fish meal, 3.0-4.1% of vegetable protein powder and 0.7-0.9% of salt.
Further, the cereal flour comprises 43-45% of corn flour, 15-17% of soybean flour and 15-18% of wheat flour by mass of the feed.
Further, the sugar comprises 1-2.5% of sucrose and 1-1.5% of lactose by mass of the feed.
Further, the amino acid comprises, by mass, 0.1-0.5% of lysine, 0.1-0.5% of methionine, 0.1-0.5% of threonine and 0.1-0.5% of valine.
The invention also provides a preparation method of the feed composition for killing the pig intestinal parasitic disease, which comprises the following steps:
(1) According to the mass fraction, 40-60% of tea saponin, 10-20% of dried ginger extract, 10-20% of garlic extract, 10-20% of litsea cubeba extract and 3-5% of pepper essential oil are subjected to first mixing to obtain the tea saponin compound product.
(2) Adding the tea saponin compound product into the feed, and performing second mixing and granulation to obtain a feed composition for killing the pig intestinal parasitosis; wherein the second mixing mass ratio of the tea saponin compound product to the feed is 50-1000 mg/kg.
Further, in the step (2), the feed is obtained by third mixing 73 to 80% of cereal flour, 2 to 4% of saccharides, 0.6 to 1.1% of calcium hydrogen phosphate, 0.5 to 1.5% of amino acid, 1.5 to 5.1% of stone powder, 0.7 to 1.4% of vegetable oil, 0.6 to 1.1% of additive, 5.1 to 8.1% of fish meal, 1.9 to 4.1% of vegetable protein powder and 0.4 to 0.9% of salt by mass.
Furthermore, in each mixing process, all the components are added in the order of mass fraction from large to small, and once adding one component, the stirring is carried out, and the stirring direction is the same direction, namely all the stirring in the clockwise direction or all the stirring in the counterclockwise direction.
Further, in the step (2), the second mixing process is to take the tea saponin compound product and the feed with equal mass, and stir in the same direction as the first mixing process in the step (1) to obtain a stirrer; and adding the stirring materials into the rest of the feed, and stirring along the same direction to obtain the feed composition for killing the pig intestinal parasitic diseases.
The invention achieves the following beneficial effects:
the feed composition for killing the pig intestinal parasitic disease comprises a feed and a tea saponin compound product. The tea saponin component in the tea saponin compound product has rich hydroxyl functional groups and good biological activity, so that the tea saponin compound product has the functions of resisting inflammation, resisting bacteria, resisting virus, killing insects and expelling parasites or is used as a biological hormone. When the tea saponin compound product and the feed are blended into the feed composition for killing the pig intestinal parasitic disease according to 50-1000 mg/kg for being eaten by piglets, the cure rate of the piglet infected by the coccidiosis can be improved, the pig immunity is improved, the effects of effectively improving the average daily gain of the piglets and reducing the toxic carrying amount of animal organisms are realized, and further, the food safety is ensured.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
It should be noted that the features in the following embodiments and examples may be combined with each other without conflict. It is also to be understood that the terminology used in the examples is for the purpose of describing particular embodiments only, and is not intended to limit the scope of the present invention.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs and the description of the present invention, and any methods, apparatuses, and materials similar or equivalent to those described in the examples of the present invention may be used to practice the present invention.
When numerical ranges are given in the examples, it is understood that both endpoints of each of the numerical ranges and any value therebetween can be selected unless the invention otherwise indicated. Test methods in which specific conditions are not specified in the following examples are generally carried out under conventional conditions or under conditions recommended by the respective manufacturers. The materials or reagents required in the following examples are commercially available unless otherwise specified.
In order to solve the problems that the feed cost is high, and the medicines remained in the pig body can bring adverse effects to the eater and the like in the prior art, the invention provides a feed composition for killing pig intestinal parasitic diseases, which comprises a feed and a tea saponin compound product; the tea saponin compound product and the feed are mixed according to the proportion of 50-1000 mg/kg; the tea saponin compound product comprises, by mass, 40-60% of tea saponin, 10-20% of a dried ginger extract, 10-20% of a garlic extract, 10-20% of a litsea cubeba extract and 3-5% of pepper essential oil.
The tea saponin component in the tea saponin compound product has rich hydroxyl functional groups and good biological activity. Therefore, the tea saponin compound product has the functions of resisting inflammation, bacteria, virus, insect and parasite or serving as a biological hormone. When the tea saponin compound product and the feed are blended into the feed composition for killing the pig intestinal parasitic disease according to 50-1000 mg/kg for being eaten by piglets, the cure rate of the piglet infected by the coccidiosis can be improved, the pig immunity is improved, the effects of effectively improving the average daily gain of the piglets and reducing the toxic carrying amount of animal organisms are realized, and further, the food safety is ensured.
The tea saponin has certain biological toxicity and quite weak hemolytic property, the tea saponin has relatively high toxicity to cold blood animals, the biological toxicity of the tea saponin can be reduced by adding 10-20% of the dried ginger extract, 10-20% of the garlic extract, 10-20% of the litsea cubeba extract and 3-5% of the zanthoxylum essential oil, and under the compatibility mode and the proportion matching, the components have synergistic effect, so that the tea saponin compound product has the maximum effect, and the effects of resisting inflammation, bacteria, viruses, killing insects and expelling parasites are realized. In addition, the garlic extract is easy to decompose, and oily components in the pepper essential oil can just effectively avoid the decomposition of the garlic extract and protect beneficial components of the garlic extract.
Further, the mixing mass ratio of the tea saponin compound product to the feed is 300-600 mg/kg; the tea saponin compound product comprises 48-55% of tea saponin, 12-18% of dried ginger extract, 12-18% of garlic extract, 12-18% of litsea cubeba extract and 3-5% of pepper essential oil by mass fraction.
Further, the feed comprises, by mass, 73-80% of cereal flour, 2-4% of saccharides, 0.6-1.1% of calcium hydrogen phosphate, 0.5-1.5% of amino acid, 1.5-5.1% of stone powder, 0.7-1.4% of vegetable oil, 0.6-1.1% of additive, 5.1-8.1% of fish meal, 1.9-4.1% of vegetable protein powder and 0.4-0.9% of salt.
Further, the feed comprises, by mass, 75-78% of cereal flour, 3-4% of saccharides, 0.8-1.0% of calcium hydrogen phosphate, 1.0-1.2% of amino acid, 2.8-4.0% of stone powder, 1.0-1.4% of vegetable oil, 0.8-1.0% of additive, 6.5-8.0 of fish meal, 3.0-4.1% of vegetable protein powder and 0.7-0.9% of salt. The matching meets the scientific feeding standard, can supply comprehensive nutrition to the piglets, and realizes the effective improvement of the average daily gain of the piglets.
The plant protein powder refers to a protein component in a plant, and the additive is generally a vitamin additive for promoting metabolism of livestock. Wherein, the additive can also comprise trace element additives such as copper sulfate and ferrous sulfate besides the vitamin additive, the utilization rate of the feed composition for killing the pig intestinal parasitic diseases can be improved by increasing the trace element additives, and the disease resistance of the pig can be improved by adding the salt.
Further, the cereal flour comprises 43-45% of corn flour, 15-17% of soybean flour and 15-18% of wheat flour by mass of the feed. By adopting the components in the cereal powder and the proportioning mode thereof, the feed can be closer to the milk of a sow, the palatability is better, and the weaning stress of piglets can be avoided.
Further, the sugar comprises 1-2.5% of sucrose and 1-1.5% of lactose by mass of the feed. 1-2.5% of sucrose is used for adjusting the taste and providing necessary sugar, and 1-1.5% of lactose is close to carbohydrate in the sow milk and can be decomposed, digested, absorbed and utilized by lactase in the digestive tract of the pig, so that the piglets have more power to support growth and development and avoid the symptoms of monophagia and the like.
Furthermore, the amino acid comprises, by mass percent of the feed, 0.1-0.5% of lysine, 0.1-0.5% of methionine, 0.1-0.5% of threonine and 0.1-0.5% of valine. Wherein, 0.1 to 0.5 percent of lysine plays a role in enhancing the body resistance of piglets, enhancing fat oxidation, promoting absorption and killing various nutrient components in the feed composition for treating pig intestinal parasitic diseases; 0.1-0.5% methionine can promote the synthesis of protein in the body of the piglet; 0.1 to 0.5 percent of threonine can adjust the amino acid balance of the feed composition for killing the pig intestinal parasitic diseases and improve the meat quality; 0.1 to 0.5 percent of valine is beneficial to restoring the damaged organism tissues of piglets, balancing blood sugar and the like. The adopted 0.1-0.5% of lysine, 0.1-0.5% of methionine, 0.1-0.5% of threonine and 0.1-0.5% of valine are matched together, so that the piglet growth and development requirements can be met, and the piglet growth and development feed is particularly suitable for piglets in the stages of diarrhea, emaciation and development obstruction.
The invention also provides a preparation method of the feed composition for killing the pig intestinal parasitic disease, which comprises the following steps:
(1) According to the mass fraction, 40-60% of tea saponin, 10-20% of dried ginger extract, 10-20% of garlic extract, 10-20% of litsea cubeba extract and 3-5% of pepper essential oil are subjected to first mixing to obtain the tea saponin compound product. The grain sizes of the tea saponin, the dried ginger extract, the garlic extract and the litsea cubeba extract are similar, and the oily components of the pepper essential oil can coat various powdery components in the tea saponin compound product by matching with the pepper essential oil, so that the garlic extract is effectively prevented from being decomposed, and a stable and effective tea saponin compound product is formed.
(2) Adding the tea saponin compound product into the feed, carrying out second mixing and granulating to obtain the feed composition for killing the pig intestinal parasitosis; wherein the third mixing mass ratio of the tea saponin compound product to the feed is 50-1000 mg/kg.
Further, in the step (2), the feed is obtained by third mixing 73 to 80% of grain powder, 2 to 4% of saccharides, 0.6 to 1.1% of calcium hydrogen phosphate, 0.5 to 1.5% of amino acid, 1.5 to 5.1% of stone powder, 0.7 to 1.4% of vegetable oil, 0.6 to 1.1% of additive, 5.1 to 8.1% of fish meal, 1.9 to 4.1% of vegetable protein powder and 0.4 to 0.9% of salt by mass.
Furthermore, in each mixing process, all the components are added in the order of mass fraction from large to small, and once adding one component, the stirring is carried out, and the stirring direction is the same direction, namely all the components are stirred in the clockwise direction or all the components are stirred in the anticlockwise direction. The tea saponin compound product and the feed which are fully and uniformly mixed can be obtained by the stirring operation, and the components can play the maximum role by uniform mixing. The stirring along the same direction can accelerate the molecular flow speed and improve the stirring efficiency.
In addition, the protein components in the feed composition for killing the pig intestinal parasitic diseases cannot be damaged by stirring in the same direction, spherical peptide chains are gradually extended and connected with each other to form a network structure, water is effectively locked, and the gelation effect of the protein is improved, so that the feed composition for killing the pig intestinal parasitic diseases can effectively inhibit the adherence of eimeria coccidia and isospora coccidia and the like to the pig intestinal tract after being eaten by pigs.
Further, in the step (2), the second mixing process is to take tea saponin compound products and feeds with equal mass, and stir in the same direction as the first mixing direction in the step (1) to obtain a stirred material; adding the stirred material into the rest feed, and stirring in the same direction to obtain the feed composition for killing pig intestinal tract parasitosis. The mixing mode can fully mix the tea saponin compound product with smaller mass fraction in the feed.
For a further understanding of the invention, reference will now be made to the following examples:
it should be noted that in examples 1-15 and comparative examples 1-8, the feeding sites are all experimental sites of animal science and technology institute of Hunan agriculture university, and a strict disinfection system is executed during the experiment to ensure no coccidian in the experimental environment; the drinking water for the experimental piglets is sterile water, and the feeding mode is the same.
In the embodiments 1 to 3, the tea saponin compound products all adopt 50% of tea saponin, 15% of dried ginger extract, 15% of garlic extract, 15% of litsea cubeba extract and 5% of pepper essential oil by mass;
in the embodiments 4 to 7, the tea saponin compound products all adopt 60% of tea saponin, 10% of dried ginger extract, 15% of garlic extract, 10% of litsea cubeba extract and 3% of pepper essential oil by mass;
in the embodiments 8 to 10, the tea saponin compound products all adopt, by mass, 55% of tea saponin, 18% of a dried ginger extract, 12% of a garlic extract, 12% of a litsea cubeba extract and 3% of zanthoxylum essential oil;
in examples 11 to 14, the tea saponin compounds all adopt 48% of tea saponin, 12% of dried ginger extract, 18% of garlic extract, 18% of litsea cubeba extract and 4% of zanthoxylum essential oil by mass fraction;
in examples 1 to 14, the feed used 45% corn flour, 16% soybean flour, 15% wheat flour, 1.5% sucrose, 1.5% lactose, 0.9% calcium hydrogen phosphate, 0.5% lysine, 0.3% methionine, 0.3% threonine, 0.3% valine, 3.8% stone flour, 1.3% vegetable oil, 0.7% vitamin additive, 0.2% copper sulfate, 7.8% fish meal, 4.1% vegetable protein powder and 0.8% salt, all by mass.
Wherein, the piglets fed in the examples 1-3 and the comparative examples 1-2 are the first batch of piglets; the selection mode of the piglet batch is that 300 piglets with the weight of 15 days old and the similar weight of the piglets at the age of 15 days are selected and randomly divided into 5 groups, each group has 6 repeated groups, and each repeated group has 10 piglets; the 5 groups were an example 1 group, an example 2 group, an example 3 group, a comparative example 1 group, and a comparative example 2 group, respectively.
The piglets fed in the examples 4-7 and the comparative examples 3-4 are the piglets of the second batch; the selection mode of the piglet batch is that 360 piglets with the weight of 15 days old and the similar weight of the piglets at the age of 15 days are selected and randomly divided into 6 groups, each group has 6 repeated groups, and each repeated group has 10 piglets; the 6 groups were example 4 group, example 5 group, example 6 group, example 7 group, comparative example 3 group, and comparative example 4 group, respectively.
The piglets fed in the examples 8-10 and the comparative examples 5-6 are the piglets of the third batch; the selection mode of the batch of piglets is that 300 piglets with the pig coccidiosis at 15 days of age, the weights of which are similar to each other at 15 days of age, are selected and randomly divided into 5 groups, each group has 6 repeated groups, and each repeated group has 10 piglets; the 6 groups were example 8 group, example 9 group, example 10 group, comparative example 5 group, and comparative example 6 group, respectively.
The fourth piglet is fed to the piglets in examples 11 to 14 and comparative examples 7 to 8; the selection mode of the batch of piglets is that 360 piglets with the pig coccidiosis at 15 days of age, the weights of which are similar to each other at 15 days of age, are selected and randomly divided into 6 groups, each group has 6 repeated groups, and each repeated group has 10 piglets; the 6 groups were example 11 group, example 12 group, example 13 group, example 14 group, comparative example 7 group, and comparative example 8 group, respectively.
Example 1
(1) Adding a tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 50mg/kg; the feed composition for killing the pig intestinal parasitosis is named as feed-50;
(2) The piglets in the group of example 1 were fed the feed composition for killing pig intestinal parasitic disease in step (1) above for 42 consecutive days (d), and the average daily gain (g), the average daily feed intake (g) and the calculated feed-weight ratio of each piglet after 14 days of feeding and 28 days of re-feeding were recorded.
Example 2
(1) Adding a tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 100mg/kg; the feed composition for killing the pig intestinal parasitosis is obtained and named as feed-100;
(2) Piglets from the group of example 2 were fed the feed composition for killing pig intestinal parasites according to step (1) above for 42 consecutive days (d) and the average daily gain (g), the average daily feed intake (g) and the calculated feed-to-weight ratio of each piglet were recorded 14 days after feeding and 28 days after feeding.
Example 3
(1) Adding a tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 300mg/kg; the feed composition for killing the pig intestinal parasitosis is named as feed-300;
(2) The piglets in the group of example 3 were fed the feed composition for killing pig intestinal parasites in step (1) above for 42 consecutive days (d), and the average daily gain (g), the average daily feed intake (g) and the calculated feed-to-weight ratio of each piglet were recorded 14 days after feeding and 28 days after feeding.
Comparative example 1
The piglets of group control 1 were fed with the feed for 42 consecutive days (d) and the average daily gain (g), daily average feed intake (g) and calculated feed to weight ratio were recorded for each piglet 14 days after feeding and 28 days after feeding.
Comparative example 2
(1) Adding antibiotics into the feed, uniformly mixing and granulating to obtain the antibiotic feed; wherein the mixing mass ratio of the antibiotics to the feed is 50mg/kg:
(2) The piglets in the group of comparative example 2 were fed with the feed composition for killing pig intestinal parasitic disease in the step (1) for 42 consecutive days (d), and the average daily gain (g), the average daily feed intake (g) and the calculated feed-weight ratio of each piglet after 14 days and 28 days of re-feeding were recorded.
Analysis example 1 analysis of growth Performance of first piglet batch
The growth performance of the piglets in the examples 1-3 and the comparative examples 1-2 which are the same as the piglets in the first batch is counted, wherein the grouping condition of the piglet test in the first batch is shown in the table 1, and the growth performance condition of the piglets in the examples 1-3 and the comparative examples 1-2 is shown in the table 2.
TABLE 1 first piglet trial cohorts
TABLE 2 piglet growth performance of examples 1-3 and comparative examples 1-2
As can be seen from the observation in tables 1 and 2, after piglets fed with the feed-50, the feed-100 and the feed-300, the piglets were found to have no significant change in the end weight, the daily average feed intake and the feed-weight ratio, but to have a greater increase in the average daily gain, compared with the piglets fed with the feed and the antibiotic feed.
Example 4
(1) Adding a tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 400mg/kg; the feed composition for killing the pig intestinal parasitosis is named as feed-400;
(2) The piglets in the group of example 4 were fed the feed composition for killing pig intestinal parasites in step (1) above for 42 consecutive days (d), and the average daily gain (g), the average daily feed intake (g) and the calculated feed-to-weight ratio of each piglet were recorded 14 days after feeding and 28 days after feeding.
Example 5
(1) Adding the tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 500mg/kg; the feed composition for killing the pig intestinal parasitosis is named as feed-500;
(2) Piglets from the group of example 5 were fed the feed composition for killing pig intestinal parasites according to step (1) above for 42 consecutive days (d), and the average daily gain (g), the average daily feed intake (g) and the calculated feed-to-weight ratio of each piglet were recorded 14 days after feeding and 28 days after feeding.
Example 6
(1) Adding a tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 600mg/kg; the feed composition for killing the pig intestinal parasitosis is named as feed-600;
(2) The piglets in the group of example 6 were fed the feed composition for killing pig intestinal parasites in step (1) above for 42 consecutive days (d), and the average daily gain (g), the average daily feed intake (g) and the calculated feed-to-weight ratio of each piglet were recorded 14 days after feeding and 28 days after feeding.
Example 7
(1) Adding the tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 1000mg/kg; the feed composition for killing the pig intestinal parasitic disease is named as feed-1000;
(2) The piglets in the group of example 7 were fed the feed composition for killing pig intestinal parasites in step (1) above for 42 consecutive days (d), and the average daily gain (g), the average daily feed intake (g) and the calculated feed-to-weight ratio of each piglet were recorded 14 days after feeding and 28 days after feeding.
Comparative example 3
The piglets of the group of comparative example 3 were fed with the feed for 42 consecutive days (d) and the average daily gain (g), the daily average feed intake (g) and the calculated feed-to-weight ratio of each piglet were recorded 14 days after feeding and 28 days after feeding.
Comparative example 4
(1) Adding antibiotics into the feed, uniformly mixing and granulating to obtain the antibiotic feed; wherein the mixing mass ratio of the antibiotics to the feed is 400mg/kg:
(2) Piglets in the group of comparative example 4 were fed with the feed composition for killing pig intestinal parasitic disease in the step (1) for 42 consecutive days (d), and the average daily gain (g), the average daily feed intake (g) and the calculated feed-to-weight ratio of each piglet were recorded 14 days after feeding and 28 days after feeding.
Analysis example 2 analysis of growth Performance of a second batch of piglets
The growth performance of the piglets in the examples 4-7 and the comparative examples 3-4 which are the same as the piglets in the second batch is counted, wherein the grouping condition of the piglet test in the second batch is shown in the table 3, and the growth performance condition of the piglets in the examples 4-7 and the comparative examples 3-4 is shown in the table 4.
TABLE 3 second batch piglet trial cohort
TABLE 4 piglet growth performance of examples 4-7 and comparative examples 3-4
As can be seen from the observation in tables 3 and 4, after piglets fed with the feed-400, the feed-500, the feed-600 and the feed-1000, the average daily gain, the average daily intake and the feed-weight ratio were not significantly changed when compared with the feed and the antibiotic feed.
Example 8
(1) Adding the tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 50mg/kg; the feed composition for killing the pig intestinal parasitosis is obtained and named as feed-50;
(2) The piglets in the group of example 8 were fed with the feed composition for killing pig intestinal parasitic disease in the above step (1) for 42 days (d) continuously, and the cure of all piglets with pig coccidiosis was counted and the average cure rate was calculated.
Example 9
(1) Adding a tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 100mg/kg; the feed composition for killing the pig intestinal parasitosis is obtained and named as feed-100;
(2) The piglets in the group of example 9 were fed with the feed composition for killing pig intestinal parasitic disease in the above step (1) for 42 days (d) continuously, and the cure of all piglets with pig coccidiosis was counted and the average cure rate was calculated.
Example 10
(1) Adding the tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 300mg/kg; the feed composition for killing the pig intestinal parasitosis is named as feed-300;
(2) The piglets in the group of example 10 were fed with the feed composition for killing pig intestinal parasitic disease in the above step (1) for 42 days (d) continuously, and the cure of all piglets with pig coccidiosis was counted and the average cure rate was calculated.
Comparative example 5
And feeding the piglets of the group of the comparative ratio 5 with the feed for 42 days (d) continuously, counting the cure conditions of all the piglets with the pig coccidiosis, and calculating the average cure rate.
Comparative example 6
(1) Adding antibiotics into the feed, uniformly mixing and granulating to obtain the antibiotic feed; wherein the mixing mass ratio of the antibiotics to the feed is 50mg/kg:
(2) And (3) feeding piglets of the group of 6 in the comparative proportion with the feed composition for killing the pig intestinal parasitic disease in the step (1) for 42 days (d), counting the cure conditions of all piglets with the pig coccidiosis, and calculating the average cure rate.
Analysis example 3 analysis of third batch of piglets for the treatment of coccidiosis in pigs
The pig coccidiosis cure conditions of the piglets in the examples 8-10 and the comparative examples 5-6 of the third batch of piglets are counted, wherein the grouping condition of the third batch of piglet tests is shown in the table 5, and the pig coccidiosis cure condition of the third batch of piglets is shown in the table 6.
TABLE 5 third batch piglet trial cohorts
TABLE 6 pig coccidiosis cure in third batch of piglets
According to the observation in the table 6, after piglets eat feed-50, feed-100 and feed-300, compared with the feed and antibiotic feed, the feed composition for killing pig intestinal parasitic diseases can effectively relieve the pig coccidiosis infection, and the cure rate is obviously higher than that of the comparative example 6 group which eats antibiotic feed, which shows that the feed composition for killing pig intestinal parasitic diseases has obvious cure effect on the piglet coccidiosis infection. In addition, the average cure rate of piglets can be found to be improved along with the increase of the proportion of the tea saponin compound product.
Example 11
(1) Adding a tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 400mg/kg; the feed composition for killing the pig intestinal parasitosis is named as feed-400;
(2) Piglets in the group of example 11 were fed with the feed composition for killing pig intestinal parasitic disease in the above step (1) for 42 days (d) continuously, and the cure of all piglets with pig coccidiosis was counted and the average cure rate was calculated.
Example 12
(1) Adding the tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 500mg/kg; the feed composition for killing the pig intestinal parasitosis is named as feed-500;
(2) The piglets in the group of example 12 were fed with the feed composition for killing pig intestinal parasitic disease in the step (1) above for 42 days (d) continuously, and the cure of all piglets with pig coccidiosis was counted and the average cure rate was calculated.
Example 13
(1) Adding a tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 600mg/kg; the feed composition for killing the pig intestinal parasitosis is named as feed-600;
(2) Piglets in the group of example 13 were fed with the feed composition for killing pig intestinal parasitic disease in the above step (1) for 42 days (d) continuously, and the cure of all piglets with pig coccidiosis was counted and the average cure rate was calculated.
Example 14
(1) Adding a tea saponin compound product into the feed, uniformly mixing and granulating, wherein the mixing mass ratio of the tea saponin compound product to the feed is 1000mg/kg; the feed composition for killing the pig intestinal parasitic disease is named as feed-1000;
(2) The piglets in the group of example 14 were fed with the feed composition for killing pig intestinal parasitic disease in the above step (1) for 42 days (d) continuously, and the cure of all piglets with pig coccidiosis was counted and the average cure rate was calculated.
Comparative example 7
And feeding the piglets of the group of the comparative ratio 7 for 42 days (d), counting the cure conditions of all piglets with the pig coccidiosis, and calculating the average cure rate.
Comparative example 8
(1) Adding antibiotics into the feed, uniformly mixing and granulating to obtain the antibiotic feed; wherein the mixing mass ratio of the antibiotics to the feed is 400mg/kg:
(2) And (3) feeding piglets of the group of the comparative proportion 8 with the feed composition for killing the pig intestinal parasitic disease in the step (1) for 42 days (d), counting the cure conditions of all piglets with the pig coccidiosis, and calculating the average cure rate.
Analysis example 4 analysis of fourth batch of piglets for the treatment of coccidiosis in pigs
The pig coccidiosis cure conditions of the piglets in the examples 11-14 and the comparative examples 7-8 of the fourth batch of piglets are counted, wherein the grouping condition of the fourth batch of piglet tests is shown in the table 7, and the pig coccidiosis cure condition of the fourth batch of piglets is shown in the table 8.
TABLE 7 fourth piglet trial cohort
TABLE 8 pig coccidiosis cure for fourth batch of piglets
According to the observation in table 8, after piglets eat feed-400, feed-500, feed-600 and feed-1000, compared with the piglets after eating feed and antibiotic feed, the feed composition for killing pig intestinal parasitic diseases can effectively relieve the infection of pig coccidia, and the cure rate is obviously higher than that of the comparative example 8 group which eat antibiotic feed, which shows that the feed composition for killing pig intestinal parasitic diseases has obvious cure effect on the piglet coccidia infection. In addition, it can be found that when the proportion of the tea saponin compound product is less than 600mg/kg, the average cure rate of piglets is still improved along with the increase of the proportion of the tea saponin compound product, but the improvement effect is not obvious as that of piglets fed with feed-50, feed-100 and feed-300. However, when the tea saponin compound product proportion is increased to 1000mg/kg, the average cure rate of piglets is reduced.
Therefore, the feed composition for killing the pig intestinal parasitic disease achieves the effects of improving the cure rate of the pig infected by coccidiosis and improving the immunity of pigs. And the effects of effectively improving the average daily gain of piglets and reducing the toxic-carrying amount of animal organisms are realized, so that the food safety is ensured.
In summary, in the above technical solutions of the present invention, the above are only preferred embodiments of the present invention, and the technical scope of the present invention is not limited thereby, and all the technical concepts of the present invention include the claims of the present invention, which are directly or indirectly applied to other related technical fields by using the equivalent structural changes made in the present specification.
Claims (10)
1. A feed composition for killing pig intestinal parasitic diseases is characterized by comprising a feed and a tea saponin compound product;
the mixing mass ratio of the tea saponin compound product to the feed is 50-1000 mg/kg;
the tea saponin compound product comprises, by mass, 40-60% of tea saponin, 10-20% of a dried ginger extract, 10-20% of a garlic extract, 10-20% of a litsea cubeba extract and 3-5% of pepper essential oil.
2. The feed composition for killing the pig intestinal parasitosis according to the claim 1, wherein the mixing mass ratio of the tea saponin compound product to the feed is 300-600 mg/kg;
the tea saponin compound product comprises 48-55% of tea saponin, 12-18% of dried ginger extract, 12-18% of garlic extract, 12-18% of litsea cubeba extract and 3-5% of pepper essential oil by mass fraction.
3. The feed composition for killing the pig intestinal parasitic disease as claimed in claim 1, wherein the feed comprises, by mass, 73-80% of cereal flour, 2-4% of saccharides, 0.6-1.1% of calcium hydrogen phosphate, 0.5-1.5% of amino acid, 1.5-5.1% of stone powder, 0.7-1.4% of vegetable oil, 0.6-1.1% of additive, 5.1-8.1% of fish meal, 1.9-4.1% of vegetable protein powder and 0.4-0.9% of salt.
4. The feed composition for killing the pig intestinal parasitic disease as claimed in claim 1, wherein the feed comprises, by mass, 75-78% of cereal flour, 3-4% of saccharides, 0.8-1.0% of calcium hydrogen phosphate, 1.0-1.2% of amino acid, 2.8-4.0% of stone powder, 1.0-1.4% of vegetable oil, 0.8-1.0% of additive, 6.5-8.0% of fish meal, 3.0-4.1% of vegetable protein powder and 0.7-0.9% of salt.
5. The feed composition for killing pig intestinal parasitic disease according to claim 3, wherein the cereal flour comprises 43-45% of corn flour, 15-17% of soybean flour and 15-18% of wheat flour by mass of the feed.
6. The feed composition for killing the pig intestinal parasitosis according to the claim 3, wherein the sugar comprises 1 to 2.5 percent of sucrose and 1 to 1.5 percent of lactose by mass of the feed;
the amino acid comprises, by mass, 0.1-0.5% of lysine, 0.1-0.5% of methionine, 0.1-0.5% of threonine and 0.1-0.5% of valine.
7. A method for preparing the feed composition for killing pig intestinal parasitosis according to claim 1, which comprises the steps of:
(1) According to the mass fraction, firstly mixing 40-60% of tea saponin, 10-20% of dried ginger extract, 10-20% of garlic extract, 10-20% of litsea cubeba extract and 3-5% of pepper essential oil to obtain a tea saponin compound product;
(2) Adding the tea saponin compound product into the feed, carrying out second mixing and granulating to obtain a feed composition for killing the pig intestinal parasitic disease;
wherein the second mixing mass ratio of the tea saponin compound product to the feed is 50-1000 mg/kg.
8. The preparation method according to claim 7, wherein the feed is obtained by third mixing 73 to 80% of grain powder, 2 to 4% of saccharide, 0.6 to 1.1% of calcium hydrogen phosphate, 0.5 to 1.5% of amino acid, 1.5 to 5.1% of stone powder, 0.7 to 1.4% of vegetable oil, 0.6 to 1.1% of additive, 5.1 to 8.1% of fish meal, 1.9 to 4.1% of vegetable protein powder and 0.4 to 0.9% of salt, in terms of mass fraction, in step (2).
9. The preparation method according to claim 7 or 8, wherein the components are added in the order of mass fraction from large to small in each mixing process, and the stirring is performed once for each added component, and the stirring directions are the same, i.e., all clockwise stirring or all counterclockwise stirring.
10. The preparation method according to claim 7, wherein in the step (2), the second mixing process is to take the tea saponin compound and the feed with equal mass, and stir in the same direction as the first mixing direction in the step (1) to obtain a stirred material;
and adding the stirring materials into the rest of the feed, and stirring along the same direction to obtain the feed composition for killing the pig intestinal parasitic diseases.
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