CN115778836A - Essential oil composition for scalp care and preparation method thereof - Google Patents
Essential oil composition for scalp care and preparation method thereof Download PDFInfo
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- 239000000341 volatile oil Substances 0.000 title claims abstract description 103
- 210000004761 scalp Anatomy 0.000 title claims abstract description 86
- 238000002360 preparation method Methods 0.000 title abstract description 18
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 90
- 239000002904 solvent Substances 0.000 claims abstract description 64
- GRWFGVWFFZKLTI-UHFFFAOYSA-N α-pinene Chemical compound CC1=CCC2C(C)(C)C1C2 GRWFGVWFFZKLTI-UHFFFAOYSA-N 0.000 claims abstract description 59
- RKWHWFONKJEUEF-GQUPQBGVSA-O Cyanidin 3-O-glucoside Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC2=C(O)C=C(O)C=C2[O+]=C1C1=CC=C(O)C(O)=C1 RKWHWFONKJEUEF-GQUPQBGVSA-O 0.000 claims abstract description 35
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The application relates to the technical field of alopecia prevention, and particularly discloses an essential oil composition for scalp care and a preparation method thereof, which can improve alopecia caused by scalp grease secretion disorder and the like. The essential oil composition for scalp care comprises a main agent and a solvent, wherein the main agent comprises beta-ethyl ketobutyrate, catechin, cyanidin-3-O-glucoside, alpha-pinene, O-hydroxyacetone, nitric acid-phylline, tretinoin, 3-amino-2,6-piperidione and ergosterol. The combination of the beta-ethyl ketobutyrate, cyanidin-3-O-glucoside and the beta-ethyl ketobutyrate can reduce the effect of androgen secreted by women on hair follicles and reduce the probability of alopecia. Alpha-pinene and catechin can enhance the effect of killing germs. The o-hydroxyacetone can permeate pores to clean impurities. The nitric acid-phylline can accelerate the shedding of necrotic epidermal cells and improve the cleaning effect. The combination of tretinoin, 3-amino-2,6-piperidione and ergosterol can promote hair growth, regulate lipid balance, and treat scalp inflammation.
Description
Technical Field
The application relates to the technical field of alopecia prevention, in particular to an essential oil composition for scalp care and a preparation method thereof.
Background
About 10 ten thousand hairs of a person exist, and it is normal that 50 to 100 hairs are shed every day and night. If too much hair is shed during shampooing, it may be alopecia. The appearance of alopecia can directly affect the beauty treatment and bring troubles to people.
The reasons for female alopecia are various, including genetic factors, nutrition imbalance, endocrine disorder, excessive use of brain, chronic diseases, contraceptive, excessive use of hair perming and dyeing, long-term use of computer, excessive weight loss and diet, improper diet, hair style influence, and the like. Some of these factors can cause disorders of scalp oil secretion, hair follicle blockage, hair follicle atrophy, etc., exacerbating the risk of hair loss. In addition to the above-mentioned causes of hair loss, products such as care agents can be used to help improve hair loss. At present, some hair loss preventing nursing agents are prepared by mixing a plurality of traditional Chinese medicines and/or western medicines, but the hair loss preventing effect is still poor.
Disclosure of Invention
In order to improve the condition that some related anti-hair loss nursing agents have poor anti-hair loss effect, the application provides an essential oil composition for scalp nursing and a preparation method thereof, so as to improve the conditions of scalp grease secretion disorder, hair follicle blockage, hair follicle atrophy and the like, and assist in improving the phenomenon of hair loss, particularly female hair loss.
In a first aspect, the present application provides an essential oil composition for scalp care, and adopts the following technical scheme.
An essential oil composition for scalp care comprises a main agent and a solvent, wherein the main agent comprises beta-ethyl ketobutyrate, catechin, cyanidin-3-O-glucoside, alpha-pinene, O-hydroxyacetone, nitric acid-phylline, tretinoin, 3-amino-2,6-piperidedione and ergosterol.
By adopting the technical scheme, the beta-ethyl ketobutyrate can reduce the adhesion of germs on the scalp and is beneficial to blocking the absorption of germs on nutrient substances. The cyanidin-3-O-glucoside molecule has a high molecular conjugation system, contains acidic and basic groups, has the function of destroying germ membrane, and can reduce the action of androgen secreted by women on hair follicles and the occurrence probability of alopecia by matching with beta-ketobutyrate. The alpha-pinene can further strengthen the function of destroying the outer membrane layer of pathogenic bacteria. Catechin can combine with germ protein and precipitate, so it has good effect of killing germ, no damage to scalp, antioxidant effect, and scalp activity improving effect. The o-hydroxyacetone is fat-soluble, can diminish inflammation and cutin, and can permeate into pores to clean impurities. The nitric acid-folic acid can accelerate the shedding of necrotic epidermal cells and improve the cleaning effect. Tretinoin can influence cell membrane flow and lipid composition, 3-amino-2,6-piperidione can improve transdermal absorption effect, promote the expansion of capillary vessels at the bottom of hair follicles, strengthen the connection effect of the hair follicles and the capillary vessels, improve the nutrition supply of the hair follicles, ergosterol can promote the development of the hair follicles, and tretinoin, 3-amino-2,6-piperidione and ergosterol have the coordination effect of promoting the growth of the hair, regulating the lipid balance and treating scalp inflammation. The synergistic effect of the above components can improve scalp lipid secretion disorder, hair follicle blockage, hair follicle atrophy, etc., to assist in improving alopecia, especially female alopecia.
As an improvement of the essential oil composition for scalp care, the main agent comprises by mass: 8-12 parts of beta-ethyl ketobutyrate, 6-10 parts of catechin, 5-9 parts of cyanidin-3-O-glucoside, 4-8 parts of alpha-pinene, 10-16 parts of O-hydroxy phenyl acetone, 5-10 parts of nitric acid-phylline, 7-11 parts of tretinoin, 7-11 parts of 3-amino-2,6-piperidedione and 5-10 parts of ergosterol.
By adopting the technical scheme, the proportions of the components are proper, the synergistic effect is obvious, the material utilization rate is high, and the conditions of scalp grease secretion disorder, hair follicle blockage, hair follicle atrophy and the like can be improved so as to assist in improving alopecia, especially female alopecia.
As a further improvement of this essential oil composition for scalp care, the main agent comprises, by mass: 10 parts of beta-tetronic acid ethyl ester, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxyacetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperiddione and 7 parts of ergosterol.
By adopting the technical scheme, the proportion of the components is optimal, the synergistic effect is best, the material utilization rate is highest, and the conditions of scalp fat secretion disorder, hair follicle blockage, hair follicle atrophy and the like can be obviously improved so as to assist in improving alopecia, particularly female alopecia.
As a further improvement of the essential oil composition for scalp care, the main agent further comprises 7-hydroxyflavone, flavanone and flavanone.
By adopting the technical scheme, the 7-hydroxyflavone can destroy the fungal cell wall, and the flavanone can assist in strengthening the function of destroying the fungal cell wall so as to kill the fungi and improve the effects of hair care and hair protection.
As an improvement of the essential oil composition for scalp care, the main agent comprises 4-6 parts by mass of the 7-hydroxyflavone, 2-4 parts by mass of the flavanone and 2-4 parts by mass of the flavanone.
By adopting the technical scheme, the proportion of the 7-hydroxyflavone, the flavanone and the flavanone is proper, and the effect of killing fungi is achieved with higher material utilization rate.
As a further improvement of this essential oil composition for scalp care, the main agent comprises 5 parts by mass of the 7-hydroxyflavone, 3 parts by mass of the flavanone and 3 parts by mass of the flavanone.
By adopting the technical scheme, the proportion of the 7-hydroxyflavone, the flavanone and the flavanone is optimal, the excellent effect of killing fungi is achieved by extremely high material utilization rate, and the effects of protecting hair and protecting hair follicles are better.
As an improvement of the essential oil composition for scalp care, the mass percentage of the main agent and the solvent is (15-20%): (80% ~ 85%).
By adopting the technical scheme, the concentration of each component of the main agent is suitable for human skin, and the effects of improving scalp health and alopecia are remarkable.
As an improvement of the essential oil composition for scalp care, the main agent also comprises fullerene, and the mass content of the fullerene in the essential oil composition is 30ppm-1000ppm.
By adopting the technical scheme, the fullerene has a high delocalized large pi conjugated system, can interact with a high molecular conjugated system in cyanidin-3-O-glucoside molecules to form a larger conjugated system, has stronger effect of damaging germ membrane layers, can further reduce the effect of androgen secreted by women on hair follicles, and more obviously reduces the probability of alopecia.
As an improvement of the essential oil composition for scalp care, the content of the fullerene in the essential oil composition is 300ppm by mass.
By adopting the technical scheme, the fullerene is matched with cyanidin-3-O-glucoside, so that the effects on alopecia and the like caused by scalp inflammation and hair follicle atrophy are better.
In a second aspect, the present application also provides a method for preparing an essential oil composition for scalp care, and adopts the following technical scheme.
A method for preparing the essential oil composition for scalp care as described above, comprising: according to the mass, 8-12 parts of beta-ethyl ketobutyrate, 6-10 parts of catechin, 5-9 parts of cyanidin-3-O-glucoside, 4-8 parts of alpha-pinene, 10-16 parts of O-hydroxy phenyl acetone, 5-10 parts of nitric acid-phylline, 7-11 parts of tretinoin, 7-11 parts of 3-amino-2,6-piperidyl dione, 5-10 parts of ergosterol and the solvent are mixed according to a proportion to obtain the essential oil composition.
By adopting the technical scheme, the preparation method of the essential oil composition is simple, the essential oil composition can be obtained only by uniformly mixing various components, and the components can be uniformly mixed by means of stirring, heating and the like. After shampooing, the essential oil composition can be uniformly applied on scalp and gently massaged for absorption.
To sum up, the application has the following beneficial effects:
the essential oil composition has synergistic effect of the components, can improve the conditions of scalp fat secretion disorder, hair follicle blockage, hair follicle atrophy and the like so as to assist in improving alopecia, and can reduce the effect of androgen secreted by women on hair follicles and the occurrence probability of alopecia by matching cyanidin-3-O-glucoside molecules with beta-ethyl ketobutyrate, so that the essential oil composition is particularly suitable for improving the phenomenon of alopecia of women.
The essential oil composition is added with 7-hydroxyflavone, flavanone and flavanone, and can help to enhance the effect of destroying fungal cell wall, kill fungi, and improve the effects of hair care and hair protection.
The fullerene is added into the essential oil composition, and can interact with a high-molecular conjugate system in cyanidin-3-O-glucoside molecules to form a larger conjugate system, so that the effect of damaging a germ membrane layer is stronger, the effect of androgen secreted by women on hair follicles can be further reduced, and the probability of alopecia can be remarkably reduced.
The essential oil composition has simple preparation method, and can be directly applied on scalp for directly supplementing nutrition to scalp, promoting cell metabolism, and recovering epidermis state. When the product is used, other improving methods such as supplementing enough nutrition, avoiding excessive use of brain, not scalding and dyeing hair, avoiding long-time use of computer, not excessive diet and the like are combined for daily conditioning and maintenance to improve the hair loss problem.
Detailed Description
The essential oil composition and the production method thereof of the present application are specifically described below by way of examples and the like.
Example 1
This example prepares an essential oil composition for scalp care, using the following specific steps.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ethyl ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione and 7 parts of ergosterol, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition.
Example 2
This example prepares an essential oil composition for scalp care, with the following specific steps.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, the main agent comprises 8 parts of beta-ethyl ketobutyrate, 10 parts of catechin, 5 parts of cyanidin-3-O-glucoside, 8 parts of alpha-pinene, 10 parts of O-hydroxy phenyl acetone, 10 parts of nitric acid-phylline, 7 parts of tretinoin, 11 parts of 3-amino-2,6-piperidione and 5 parts of ergosterol, wherein the mass percent of the main agent to the solvent is 15%:85% to obtain the essential oil composition.
Example 3
This example prepares an essential oil composition for scalp care, with the following specific steps.
By mass, taking a mixed solution of 8:2 water and ethanol as a solvent, dissolving a main agent into the solvent, wherein the main agent comprises 12 parts of beta-ethyl ketobutyrate, 6 parts of catechin, 9 parts of cyanidin-3-O-glucoside, 4 parts of alpha-pinene, 16 parts of O-hydroxyphenylacetone, 5 parts of nitric acid-phylline, 11 parts of tretinoin, 7 parts of 3-amino-2,6-piperidione and 10 parts of ergosterol, and the mass percentage of the main agent to the solvent is 17%:83% to obtain the essential oil composition.
Example 4
In this example, an essential oil composition for scalp care was prepared, and compared to example 1, 7-hydroxyflavone, flavanone and flavanone were added to the base composition of this example, and the specific preparation steps were as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione, 7 parts of ergosterol, 5 parts of 7-hydroxyflavone, 3 parts of flavanone and 3 parts of flavanone, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition.
Example 5
In this example, an essential oil composition for scalp care was prepared, and compared to example 1, 7-hydroxyflavone, flavanone and flavanone were added to the base composition of this example, and the specific preparation steps were as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione, 7 parts of ergosterol, 4 parts of 7-hydroxyflavone, 4 parts of flavanone and 2 parts of flavanone, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition.
Example 6
In this example, an essential oil composition for scalp care was prepared, and compared to example 1, 7-hydroxyflavone, flavanone and flavanone were added to the base composition of this example, and the specific preparation steps were as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione, 7 parts of ergosterol, 6 parts of 7-hydroxyflavone, 2 parts of flavanone and 4 parts of flavanone, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition.
Example 7
In this example, an essential oil composition for scalp care was prepared, and the main agent of this example was further added with fullerene as compared with example 1, and the specific preparation steps were as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ethyl ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione, 7 parts of ergosterol and fullerene, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition, wherein the mass content of the fullerene in the essential oil composition is 300ppm.
Example 8
In this example, an essential oil composition for scalp care was prepared, and the main agent of this example was further added with fullerene as compared with example 4, and the specific preparation steps were as follows.
According to the mass percent, a mixed solution of water and ethanol of 8:2 is used as a solvent, a main agent is taken and dissolved in the solvent, and the main agent comprises 10 parts of beta-tetronic acid ethyl ester, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione, 7 parts of ergosterol, 5 parts of 7-hydroxyflavone, 3 parts of flavanone and fullerene, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition, wherein the mass content of the fullerene in the essential oil composition is 300ppm.
Example 9
This example prepared an essential oil composition for scalp care, which was different in fullerene content from example 8, and was prepared as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione, 7 parts of ergosterol, 5 parts of 7-hydroxyflavone, 3 parts of flavanone and fullerene, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition, wherein the mass content of the fullerene in the essential oil composition is 30ppm.
Example 10
This example prepared an essential oil composition for scalp care, which was different in fullerene content from example 8, and was prepared as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione, 7 parts of ergosterol, 5 parts of 7-hydroxyflavone, 3 parts of flavanone and fullerene, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition, wherein the mass content of the fullerene in the essential oil composition is 1000ppm.
Comparative example 1
The present comparative example prepared an essential oil composition for scalp care, and compared to example 1, the main agent of the present comparative example did not include ethyl β -ketobutyrate, and the specific preparation procedure was as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is taken and dissolved in the solvent, and the main agent comprises 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione and 7 parts of ergosterol, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition.
Comparative example 2
This comparative example prepared an essential oil composition for scalp care, and compared to example 1, the main agent of this comparative example did not include catechin, and the specific preparation procedure was as follows.
According to the mass percent, the mixed solution of water and ethanol of 8:2 is used as a solvent, a main agent is taken and dissolved in the solvent, the main agent comprises 10 parts of beta-ketobutyric acid ethyl ester, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione and 7 parts of ergosterol, wherein the mass percent of the main agent and the solvent is 20%:80% to obtain the essential oil composition.
Comparative example 3
This comparative example prepared an essential oil composition for scalp care, which did not include cyanidin-3-O-glucoside as the main agent compared with example 1, and was prepared as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, the main agent comprises 10 parts of beta-ethyl ketobutyrate, 8 parts of catechin, 6 parts of alpha-pinene, 13 parts of o-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidedione and 7 parts of ergosterol, and the mass percent of the main agent and the solvent is 20%:80% to obtain the essential oil composition.
Comparative example 4
This comparative example prepared an essential oil composition for scalp care, and compared with example 1, the main agent of this comparative example did not include α -pinene, and the specific preparation steps were as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ethyl ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione and 7 parts of ergosterol, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition.
Comparative example 5
This comparative example prepared an essential oil composition for scalp care, and compared with example 1, the main agent of this comparative example did not include o-hydroxyacetone, and was specifically prepared as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ethyl ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione and 7 parts of ergosterol, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition.
Comparative example 6
This comparative example prepared an essential oil composition for scalp care, and compared to example 1, the main agent of this comparative example did not include nitric acid-folic acid, and the specific preparation procedure was as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ethyl ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidione and 7 parts of ergosterol, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition.
Comparative example 7
This comparative example prepared an essential oil composition for scalp care, and compared to example 1, the main agent of this comparative example did not include tretinoin, and the specific preparation procedure was as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ethyl ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of 3-amino-2,6-piperidione and 7 parts of ergosterol, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition.
Comparative example 8
This comparative example prepared an essential oil composition for scalp care, and compared to example 1, the main agent of this comparative example did not include 3-amino-2,6-piperidinedione, and was prepared as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, the main agent comprises 10 parts of beta-ethyl ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin and 7 parts of ergosterol, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition.
Comparative example 9
This comparative example prepared an essential oil composition for scalp care, and compared to example 1, the main agent of this comparative example did not include lysergic alcohol, and the specific preparation procedure was as follows.
According to the mass percent, a mixed solution of 8:2 water and ethanol is used as a solvent, a main agent is dissolved in the solvent, and the main agent comprises 10 parts of beta-ethyl ketobutyrate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxy phenyl acetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin and 9 parts of 3-amino-2,6-piperidedione, wherein the mass percent of the main agent to the solvent is 20%:80% to obtain the essential oil composition.
Test example 1
The essential oil compositions prepared in each example and comparative example were applied to the heads of 57 female scalp patients once a day, 10ml each time, and the change after 20 days was observed. The test uses a hair follicle detector to detect the scalp, including the conditions of scalp cleanliness, color, hair follicle blockage, oil secretion, germ infection, hair growth, and the like, and the results are shown in table 1 below.
Table 1 test of applying the essential oil composition prepared in each example and comparative example to the head of a scalp patient
As can be seen from table 1, the essential oil compositions prepared in examples 1 to 10 are effective in improving the symptoms of scalp inflammation, hair follicle obstruction, hair follicle atrophy, excessive scalp oil production, etc., and have a good beneficial effect in improving alopecia. Of examples 1 to 3, example 1 was most effective in ameliorating scalp inflammation, excessive scalp oil, hair follicle clogging, and hair loss. The essential oil compositions prepared in examples 4 to 6 were effective in ameliorating tinea capitis caused by fungal infection by adding 7-hydroxyflavone, flavanone and flavanone. The essential oil composition prepared in example 7 was not effective in improving tinea capitis due to fungal infection without the addition of 7-hydroxyflavone, flavanone and flavanone. The essential oil compositions prepared in examples 8 to 10 added with 7-hydroxyflavone, flavanone and flavanone were also effective in ameliorating tinea capitis caused by fungal infection. The essential oil compositions prepared in examples 8 to 10 further added with fullerene have good effects on improving alopecia and scalp inflammation.
The essential oil composition prepared in comparative example 1 was not added with ethyl β -ketobutyrate, and had no significant improvement effect on scalp inflammation, hair loss caused by hair follicle atrophy, and the like.
The essential oil composition prepared in comparative example 2 was not added with catechins, and had a limited effect of improving scalp inflammation.
The essential oil composition prepared in comparative example 3 did not contain cyanidin-3-O-glucoside, and had an insignificant improvement effect on scalp inflammation, hair loss caused by follicular atrophy, and the like.
The essential oil composition prepared in comparative example 4, to which no α -pinene was added, had a reduced effect of improving scalp inflammation and dandruff.
The essential oil composition prepared in comparative example 5, in which o-hydroxyacetone was not added, had a reduced scalp cleansing effect.
The essential oil composition prepared in comparative example 6 has no nitric acid-folic acid added, and has reduced effects of cleaning dandruff and dredging hair follicle blockage.
The essential oil composition prepared in comparative example 7 did not contain tretinoin, and had no significant improvement effect on scalp inflammation, hair follicle blockage and scalp lipid secretion loss.
The essential oil composition prepared in comparative example 8, to which 3-amino-2,6-piperidinedione was not added, had no significant improvement effect on scalp inflammation, hair follicle blockage and scalp lipid secretion loss.
The essential oil composition prepared in comparative example 9, to which ergosterol was not added, had no significant improvement effect on scalp inflammation, hair follicle blockage and scalp lipid secretion loss.
The essential oil compositions prepared in examples 1 to 10 had the following improving effects in addition to the above test effects:
relaxing muscles and tendons, promoting blood circulation, improving epidermal microcirculation, promoting cell regeneration, enhancing skin function and activity, and improving skin color to make skin more compact and elastic;
eliminating accumulation of cytotoxin and relieving epidermal edema;
improving chickenpox, herpes, wound suppuration, wart, sore, burn, sunburn, pruritus, etc.;
balancing hormone action, and improving female alopecia;
improving insomnia, neuralgia, headache and vertigo.
The essential oil compositions prepared in examples 1-10 can be directly applied to the scalp to supplement nutrients directly to the scalp, promote cell metabolism, and restore the epidermal state. The product can relieve alopecia, promote hair growth, and improve alopecia by supplementing nutrition, preventing excessive brain use, no scald and hair dyeing, preventing long-term use of computer, and no excessive diet.
The above embodiments are only preferred embodiments of the present application, and the protection scope of the present application is not limited to the above embodiments, and all technical solutions belonging to the idea of the present application belong to the protection scope of the present application. It should be noted that several modifications and finishes without departing from the principle of the present application will occur to those skilled in the art, and such modifications and finishes should also be considered to fall within the scope of the present application.
Claims (10)
1. The essential oil composition for scalp care is characterized by comprising a main agent and a solvent, wherein the main agent comprises beta-tetronic acid ethyl ester, catechin, cyanidin-3-O-glucoside, alpha-pinene, O-hydroxyacetone, nitric acid-phylline, tretinoin, 3-amino-2,6-piperiddione and ergosterol.
2. An essential oil composition for scalp care according to claim 1, characterized in that the main agent comprises, by mass: 8-12 parts of beta-ethyl ketobutyrate, 6-10 parts of catechin, 5-9 parts of cyanidin-3-O-glucoside, 4-8 parts of alpha-pinene, 10-16 parts of O-hydroxy phenyl acetone, 5-10 parts of nitric acid-phylline, 7-11 parts of tretinoin, 7-11 parts of 3-amino-2,6-piperidedione and 5-10 parts of ergosterol.
3. An essential oil composition for scalp care according to claim 2, characterized in that the main agent comprises, by mass: 10 parts of beta-ethyl bunonate, 8 parts of catechin, 7 parts of cyanidin-3-O-glucoside, 6 parts of alpha-pinene, 13 parts of O-hydroxyacetone, 7 parts of nitric acid-phylline, 9 parts of tretinoin, 9 parts of 3-amino-2,6-piperidedione and 7 parts of ergosterol.
4. An essential oil composition for scalp care according to claim 2 or 3, characterized in that the base further comprises 7-hydroxyflavone, flavanone and flavanone.
5. An essential oil composition for scalp care according to claim 4, characterized in that the main agent comprises 4-6 parts by mass of said 7-hydroxyflavone, 2-4 parts by mass of said flavanone and 2-4 parts by mass of said flavanone.
6. An essential oil composition for scalp care according to claim 5, characterized in that the main agent comprises 5 parts by mass of the 7-hydroxyflavone, 3 parts by mass of the flavanone and 3 parts by mass of the flavanone.
7. The essential oil composition for scalp care according to claim 1, wherein the mass percentage of the main agent and the solvent is (15% to 20%): (80% ~ 85%).
8. The essential oil composition for scalp care according to claim 1, wherein the base further comprises fullerene, and the fullerene is contained in the essential oil composition in an amount of 30ppm to 1000ppm by mass.
9. The scalp care essential oil composition according to claim 8, wherein the fullerene is contained in the essential oil composition in an amount of 300ppm by mass.
10. A method for preparing an essential oil composition for scalp care according to any one of claims 1 to 9, characterized in that 8 to 12 parts by mass of the ethyl β -ketobutyrate, 6 to 10 parts by mass of the catechin, 5 to 9 parts by mass of the cyanidin-3-O-glucoside, 4 to 8 parts by mass of the α -pinene, 10 to 16 parts by mass of the O-hydroxyacetone, 5 to 10 parts by mass of the nitric acid-folic acid, 7 to 11 parts by mass of the tretinoin, 7 to 11 parts by mass of the 3-amino-2,6-piperidinedione, 5 to 10 parts by mass of the ergosterol and the solvent are mixed in proportion to obtain the essential oil composition.
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|---|---|---|---|---|
| DE10133203A1 (en) * | 2001-07-07 | 2003-01-16 | Beiersdorf Ag | Topical compositions containing catechins and/or their gallate esters, useful e.g. for treating or preventing dry skin or inflammatory conditions of the skin, e.g. eczema, polymorphic light dermatosis or psoriasis |
| TW200513268A (en) * | 2003-10-09 | 2005-04-16 | Kun-Han Shi | A natural composition for eliminating obstacles on scalp or between hair and producing method thereof |
| US20110059907A1 (en) * | 2008-06-16 | 2011-03-10 | Island Kinetics Inc. | Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care |
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2023
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10133203A1 (en) * | 2001-07-07 | 2003-01-16 | Beiersdorf Ag | Topical compositions containing catechins and/or their gallate esters, useful e.g. for treating or preventing dry skin or inflammatory conditions of the skin, e.g. eczema, polymorphic light dermatosis or psoriasis |
| TW200513268A (en) * | 2003-10-09 | 2005-04-16 | Kun-Han Shi | A natural composition for eliminating obstacles on scalp or between hair and producing method thereof |
| US20110059907A1 (en) * | 2008-06-16 | 2011-03-10 | Island Kinetics Inc. | Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care |
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