CN115777935A - Method for preparing buckwheat rutin from buckwheat flavone extract - Google Patents
Method for preparing buckwheat rutin from buckwheat flavone extract Download PDFInfo
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- CN115777935A CN115777935A CN202211697267.1A CN202211697267A CN115777935A CN 115777935 A CN115777935 A CN 115777935A CN 202211697267 A CN202211697267 A CN 202211697267A CN 115777935 A CN115777935 A CN 115777935A
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- rutin
- buckwheat
- flavone extract
- alcohol
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- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 title claims abstract description 40
- 229930003944 flavone Natural products 0.000 title claims abstract description 40
- 150000002212 flavone derivatives Chemical class 0.000 title claims abstract description 40
- 235000011949 flavones Nutrition 0.000 title claims abstract description 40
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 title claims abstract description 40
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 title claims abstract description 36
- IVTMALDHFAHOGL-UHFFFAOYSA-N eriodictyol 7-O-rutinoside Natural products OC1C(O)C(O)C(C)OC1OCC1C(O)C(O)C(O)C(OC=2C=C3C(C(C(O)=C(O3)C=3C=C(O)C(O)=CC=3)=O)=C(O)C=2)O1 IVTMALDHFAHOGL-UHFFFAOYSA-N 0.000 title claims abstract description 36
- FDRQPMVGJOQVTL-UHFFFAOYSA-N quercetin rutinoside Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 FDRQPMVGJOQVTL-UHFFFAOYSA-N 0.000 title claims abstract description 36
- 235000005493 rutin Nutrition 0.000 title claims abstract description 36
- IKGXIBQEEMLURG-BKUODXTLSA-N rutin Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@@H]1OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-BKUODXTLSA-N 0.000 title claims abstract description 36
- ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 title claims abstract description 36
- 229960004555 rutoside Drugs 0.000 title claims abstract description 36
- 241000219051 Fagopyrum Species 0.000 title claims abstract description 28
- 235000009419 Fagopyrum esculentum Nutrition 0.000 title claims abstract description 28
- 238000000034 method Methods 0.000 title claims abstract description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 67
- 229930003935 flavonoid Natural products 0.000 claims abstract description 19
- 150000002215 flavonoids Chemical class 0.000 claims abstract description 19
- 235000017173 flavonoids Nutrition 0.000 claims abstract description 19
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 claims abstract description 18
- 238000010438 heat treatment Methods 0.000 claims abstract description 17
- 239000004519 grease Substances 0.000 claims abstract description 16
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 claims abstract description 9
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 claims abstract description 9
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 claims abstract description 9
- 235000005875 quercetin Nutrition 0.000 claims abstract description 9
- 229960001285 quercetin Drugs 0.000 claims abstract description 9
- 238000001914 filtration Methods 0.000 claims abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 6
- 230000009471 action Effects 0.000 claims description 5
- 238000004064 recycling Methods 0.000 claims description 5
- 244000130270 Fagopyrum tataricum Species 0.000 abstract description 17
- 235000014693 Fagopyrum tataricum Nutrition 0.000 abstract description 17
- 235000013305 food Nutrition 0.000 abstract description 7
- 230000008901 benefit Effects 0.000 abstract description 3
- 238000002360 preparation method Methods 0.000 description 4
- 230000036541 health Effects 0.000 description 3
- 241000282414 Homo sapiens Species 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
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- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a method for preparing buckwheat rutin from buckwheat flavone extract, which comprises the following steps: preparing a dissolving solution: the flavone extract is processed by using alcohol with the concentration of 10-35 percent v/v according to the proportion that the flavone extract: the alcohol is the proportion of 1 to 1; and (3) filtering oil: removing grease by a filter at the temperature of 15-30 ℃; heating the solution: heating the dissolved solution to 60-80 deg.C for 5-10 min for volatilizing ethanol in the dissolved solution, and volatilizing part of rutin and quercetin in the dissolved solution by ethanol volatilization; condensing and recovering the volatilized ethanol and rutin; concentration: and concentrating the condensate to obtain concentrated paste, wherein the water content of the concentrated paste is 20% -50%, the content of the wet-based total flavonoids is 50% -80%, and the ratio of rutin in the wet-based total flavonoids is 80% -95%. Has the advantage of improving the quality and functional stability of the flavone tartary buckwheat food by improving the content proportion of rutin in the flavone extract.
Description
Technical Field
The invention relates to the field of preparation of buckwheat rutin, and in particular relates to a method for preparing buckwheat rutin from buckwheat flavone extract.
Background
At present, the incidence of hyperlipidemia, obesity, diabetes and the like caused by unreasonable diet is continuously increased, and the health of human beings is threatened all the time. With the development of science and technology, the improvement of the living standard of people, the nutrition and health care value of the tartary buckwheat has been paid attention by people, the tartary buckwheat has high medicinal value, which is recorded early on ancient books of China, for example, in the book Bencao gang mu, the buckwheat can strengthen the stomach, tonify qi, continue spirit, press erysipelas when eating and drinking, and also can reduce qi, widen the lung, grind and remove stasis, clear heat, swell and wind pain, reduce white turbid leucorrhea and spleen accumulation and diarrhea. Tartary buckwheat or tartary buckwheat products are continuously favored by people at home and abroad.
At present, tartary buckwheat is taken as a raw material, tartary buckwheat flavone is extracted by an alcohol extraction method and then is enriched into various tartary buckwheat foods, and the common method for producing high-flavone tartary buckwheat foods is provided. However, the buckwheat flavonoids are the combination of various flavonoids, and meanwhile, different flavonoids in the buckwheat flavonoids have different stability in various buckwheat foods and have different health care functions in human bodies. Therefore, the alcohol-extracted tartary buckwheat flavone extract is prepared into high-content tartary buckwheat rutin, and the preparation method has important significance on the quality and the functional stability of high-flavone tartary buckwheat food
Disclosure of Invention
The invention aims to provide a method for preparing buckwheat rutin from buckwheat flavone extract, which has the advantage of improving the quality and functional stability of flavone buckwheat food by improving the content proportion of rutin in the flavone extract.
In order to achieve the purpose, the invention adopts the technical scheme that: a method for preparing tartary buckwheat rutin from tartary buckwheat flavone extract comprises the following steps:
s1, preparation of a dissolving solution: the flavone extract is processed by using alcohol with the concentration of 10-35 percent v/v according to the proportion that the flavone extract: the alcohol is the proportion of 1 to 1;
s2, filtering oil: when the solution is prepared in the step S1, grease can be separated out from the solution under the action of alcohol, and the grease is removed by adopting a filter at the temperature of 15-30 ℃;
s3, heating the solution: heating the solution without the grease in the step S2 to 60-80 ℃, and heating for 5-10 min for volatilizing ethanol in the solution, and volatilizing part of rutin and part of unconverted quercetin in the solution through the volatilization of the ethanol;
s4, condensing and recycling the ethanol and the rutin volatilized in the step S3;
s5, concentrating: and (4) concentrating the dissolved solution obtained in the step (S3) to obtain a concentrated paste, wherein the water content of the concentrated paste is 20% -50%, the content of wet-based total flavonoids is 50% -80%, and the ratio of rutin in the wet-based total flavonoids is 80% -95%.
Further, the alcohol concentration was 35% v/v, the ratio of flavone extract to alcohol was 1.
Further, the concentration of alcohol was 25% v/v, the ratio of flavone extract to alcohol was 1.
Further, the concentration of alcohol was 10% v/v, the ratio of flavone extract to alcohol was 1.
Compared with the prior art, the invention has the advantages that: the quality and the functional stability of the flavone tartary buckwheat food are improved by improving the content proportion of rutin in the flavone extract.
Detailed Description
The present invention will be further explained below.
Example 1: a method for preparing buckwheat rutin from buckwheat flavone extract comprises the following steps:
s1, preparing a dissolving solution: the flavone extract is mixed with 35 v/v% alcohol according to the proportion of the flavone extract: the alcohol is 1;
s2, filtering out oil: when the solution is prepared in the step S1, grease can be separated out from the solution under the action of alcohol, and the grease is removed by adopting a filter at the temperature of 15-30 ℃;
s3, heating the solution: heating the dissolved solution from which the grease is removed in the step S2 to 80 ℃, and heating for 10min for volatilizing ethanol in the dissolved solution, and volatilizing part of rutin and quercetin in the dissolved solution through the volatilization of the ethanol;
s4, condensing and recycling the ethanol and the rutin volatilized in the step S3;
s5, concentrating: and (4) concentrating the dissolved solution obtained in the step (S3) to obtain a concentrated paste, wherein the water content of the concentrated paste is 20%, the content of the wet-based total flavonoids is 80%, the content of rutin in the wet-based total flavonoids is 95%, the content of quercetin is 4%, and the content of other flavonoids is 1%.
Example 2: a method for preparing tartary buckwheat rutin from tartary buckwheat flavone extract comprises the following steps:
s1, preparing a dissolving solution: the flavone extract is processed by using 25 percent v/v alcohol according to the proportion that the flavone extract: dissolving flavone extract with ethanol at a ratio of 1;
s2, filtering out oil: when the solution is prepared in the step S1, grease can be separated out from the solution under the action of alcohol, and the grease is removed by adopting a filter at the temperature of 15-30 ℃;
s3, heating the solution: heating the solution without the grease in the step S2 to 70 ℃, and heating for 10min for volatilizing ethanol in the solution, and volatilizing part of rutin and quercetin in the solution through the volatilization of the ethanol;
s4, condensing and recycling the ethanol and the rutin volatilized in the step S3;
s5, concentrating: and (4) concentrating the dissolved solution in the step (S3) to obtain a concentrated paste, wherein the water content of the concentrated paste is 30%, the content of the wet-based total flavonoids is 70%, the ratio of rutin in the wet-based total flavonoids is 90%, the ratio of quercetin is 8%, and the ratio of other flavonoids is 2%.
Example 3: a method for preparing buckwheat rutin from buckwheat flavone extract comprises the following steps:
s1, preparation of a dissolving solution: the flavone extract is mixed with alcohol with the concentration of 10 percent v/v according to the weight percentage of the flavone extract: the alcohol is in a ratio of 1;
s2, filtering out oil: when the solution is prepared in the step S1, grease can be separated out from the solution under the action of alcohol, and the grease is removed by adopting a filter at the temperature of 15-30 ℃;
s3, heating the solution: heating the dissolved solution from which the grease is removed in the step S2 to 60 ℃, heating for 5min for volatilizing ethanol in the dissolved solution, and volatilizing part of rutin and quercetin in the dissolved solution through the volatilization of the ethanol;
s4, condensing and recycling the ethanol and the rutin volatilized in the step S3;
s5, concentrating: and (4) concentrating the dissolved solution in the step (S3) to obtain a concentrated paste, wherein the water content of the concentrated paste is 50%, the content of the wet-based total flavonoids is 50%, the ratio of rutin in the wet-based total flavonoids is 80%, the content of quercetin is 10%, and the content of other flavonoids is 10%.
The principle and the embodiment of the present invention are explained by applying specific examples, and the above description of the embodiments is only used to help understanding the method and the core idea of the present invention; while the invention has been described with reference to specific embodiments and applications, it will be apparent to those skilled in the art that various changes in form and detail may be made therein without departing from the spirit and scope of the invention as defined in the appended claims.
Claims (4)
1. A method for preparing buckwheat rutin from buckwheat flavone extract is characterized by comprising the following steps: the method comprises the following steps:
s1, preparing a dissolving solution: the flavone extract is processed by using low-concentration alcohol with the concentration of 10-35 percent v/v according to the proportion that the flavone extract: the alcohol is the proportion of 1 to 1;
s2, filtering out oil: when the solution is prepared in the step S1, grease can be separated out from the solution under the action of alcohol, and the grease is removed by adopting a filter at the temperature of 15-30 ℃;
s3, heating the solution: heating the dissolved solution from which the grease is removed in the step S2 to 60-80 ℃, and heating for 5-10 min for volatilizing ethanol in the dissolved solution, and volatilizing part of rutin and quercetin in the dissolved solution through the volatilization of the ethanol;
s4, condensing and recycling the ethanol and rutin volatilized in the step S3;
s5, concentrating: and (4) concentrating the dissolved solution obtained in the step (S3) to obtain a concentrated paste, wherein the water content of the concentrated paste is 20% -50%, the content of wet-based total flavonoids is 50% -80%, and the ratio of rutin in the wet-based total flavonoids is 80% -95%.
2. The method for preparing buckwheat rutin from buckwheat flavone extract according to claim 1, which is characterized in that: the concentration of alcohol was 35% v/v, the ratio of flavone extract to alcohol was 1.
3. The method for preparing buckwheat rutin from buckwheat flavone extract according to claim 1, which is characterized in that: the concentration of alcohol was 25% v/v, the ratio of flavone extract to alcohol was 1.
4. The method for preparing buckwheat rutin by using buckwheat flavone extract according to claim 1, which is characterized by comprising the following steps: the concentration of alcohol was 10% v/v, the ratio of flavone extract to alcohol was 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211697267.1A CN115777935A (en) | 2022-12-28 | 2022-12-28 | Method for preparing buckwheat rutin from buckwheat flavone extract |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202211697267.1A CN115777935A (en) | 2022-12-28 | 2022-12-28 | Method for preparing buckwheat rutin from buckwheat flavone extract |
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| CN115777935A true CN115777935A (en) | 2023-03-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202211697267.1A Pending CN115777935A (en) | 2022-12-28 | 2022-12-28 | Method for preparing buckwheat rutin from buckwheat flavone extract |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060099690A1 (en) * | 2002-09-23 | 2006-05-11 | Her Majesty The Queen In Right Of Canada, As Repre | Extraction, purification and conversion of flavonoids from plant biomass |
| CN101062114A (en) * | 2007-05-28 | 2007-10-31 | 山西省农业科学院农产品综合利用研究所 | Method for distilling flavone from tartary buckwheat bran |
| CN105249152A (en) * | 2015-09-08 | 2016-01-20 | 西昌航飞苦荞科技发展有限公司 | Tartary buckwheat flavone extract, food or health care food thereof and production method |
| CN111423404A (en) * | 2020-04-29 | 2020-07-17 | 廊坊师范学院 | Method for separating rutin and quercetin from black tartary buckwheat |
-
2022
- 2022-12-28 CN CN202211697267.1A patent/CN115777935A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060099690A1 (en) * | 2002-09-23 | 2006-05-11 | Her Majesty The Queen In Right Of Canada, As Repre | Extraction, purification and conversion of flavonoids from plant biomass |
| CN101062114A (en) * | 2007-05-28 | 2007-10-31 | 山西省农业科学院农产品综合利用研究所 | Method for distilling flavone from tartary buckwheat bran |
| CN105249152A (en) * | 2015-09-08 | 2016-01-20 | 西昌航飞苦荞科技发展有限公司 | Tartary buckwheat flavone extract, food or health care food thereof and production method |
| CN111423404A (en) * | 2020-04-29 | 2020-07-17 | 廊坊师范学院 | Method for separating rutin and quercetin from black tartary buckwheat |
Non-Patent Citations (1)
| Title |
|---|
| 梁敬钰: "天然药物化学实验与指导", 中国医药科技出版社, pages: 35 - 36 * |
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