CN115768443A - Cd19定向嵌合抗原受体t细胞组合物和方法及其用途 - Google Patents

Cd19定向嵌合抗原受体t细胞组合物和方法及其用途 Download PDF

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Publication number
CN115768443A
CN115768443A CN202180027165.6A CN202180027165A CN115768443A CN 115768443 A CN115768443 A CN 115768443A CN 202180027165 A CN202180027165 A CN 202180027165A CN 115768443 A CN115768443 A CN 115768443A
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cells
car
composition
phenotype
ccr7
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Chinese (zh)
Inventor
M·韦斯特比
A·W·布里格斯
D·G·库格勒
R·G·卡斯帕里
C·陈
D·瓦伦
L·杰美罗
C·斯坦伯格
M·P·波尔托拉克
K·巴舒尔
O·巴图尔维奇
N·基拉武兹
K·黑格
M·伯吉斯
K·吴
R·A·赛尔门
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Juno Therapeutics Inc
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Juno Therapeutics Inc
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CN202180027165.6A 2020-02-12 2021-02-11 Cd19定向嵌合抗原受体t细胞组合物和方法及其用途 Pending CN115768443A (zh)

Applications Claiming Priority (3)

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US202062975724P 2020-02-12 2020-02-12
US62/975,724 2020-02-12
PCT/US2021/017739 WO2021163391A1 (en) 2020-02-12 2021-02-11 Cd19-directed chimeric antigen receptor t cell compositions and methods and uses thereof

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CN115768443A true CN115768443A (zh) 2023-03-07

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US (1) US20230190798A1 (https=)
EP (1) EP4103204A1 (https=)
JP (1) JP2023519098A (https=)
KR (1) KR20220152220A (https=)
CN (1) CN115768443A (https=)
AU (1) AU2021220875A1 (https=)
BR (1) BR112022015236A2 (https=)
CA (1) CA3169672A1 (https=)
IL (1) IL295384B1 (https=)
MX (1) MX2022009832A (https=)
WO (1) WO2021163391A1 (https=)

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RU2763795C2 (ru) 2014-04-23 2022-01-11 Джуно Терапьютикс, Инк. Способы выделения, культивирования и генетической инженерии популяций клеток иммунной системы для адоптивной терапии
CN113474450A (zh) 2018-08-09 2021-10-01 朱诺治疗学股份有限公司 产生工程化细胞的方法以及所述工程化细胞的组合物
AU2020232691B2 (en) 2019-03-05 2023-06-29 Nkarta, Inc. CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
WO2024097315A2 (en) * 2022-11-02 2024-05-10 Sana Biotechnology, Inc. Cell therapy products and methods for producing same
EP4687963A1 (en) * 2023-03-30 2026-02-11 Cabaletta Bio, Inc. Methods and compositions for treating autoimmune diseases
US20240368273A1 (en) * 2023-05-03 2024-11-07 PELL Bio-Med Technology Co., Ltd. Murine anti-cd19 chimeric antigen receptor for treating cancer
KR20250074841A (ko) * 2023-11-20 2025-05-28 (재) 스크립스코리아항체연구원 키메라 항원 수용체를 발현하는 면역 세포 및 트렙타비딘 스캐폴드 항체 유사 단백질을 포함하는 항암용 조성물, 및 이의 용도

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