CN115698062A - 表达嵌合抗原受体并具有降低的促炎细胞因子信号传导的经基因修饰的免疫细胞 - Google Patents

表达嵌合抗原受体并具有降低的促炎细胞因子信号传导的经基因修饰的免疫细胞 Download PDF

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CN115698062A
CN115698062A CN202180026149.5A CN202180026149A CN115698062A CN 115698062 A CN115698062 A CN 115698062A CN 202180026149 A CN202180026149 A CN 202180026149A CN 115698062 A CN115698062 A CN 115698062A
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cells
immune cells
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B.胡
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Celledit LLC
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CN202180026149.5A 2020-04-06 2021-04-06 表达嵌合抗原受体并具有降低的促炎细胞因子信号传导的经基因修饰的免疫细胞 Pending CN115698062A (zh)

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US202063005684P 2020-04-06 2020-04-06
US63/005,684 2020-04-06
PCT/US2021/025906 WO2021207150A1 (en) 2020-04-06 2021-04-06 Genetically modified immune cells expressing a chimeric antigen receptor and having reduced proinflammatory cytokine signaling

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CN117965633A (zh) * 2024-04-01 2024-05-03 北京双赢科创生物科技有限公司 一种IFNγ受体敲除的CAR-T细胞的制备方法与应用

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WO2023060126A1 (en) * 2021-10-06 2023-04-13 Dana-Farber Cancer Institute, Inc. Engineered cytokine receptors for tunable adoptive cell therapy
CN114350665A (zh) * 2022-01-19 2022-04-15 上海优替济生生物医药有限公司 IFN-γ抑制剂及其用途
US20230256065A1 (en) * 2022-02-16 2023-08-17 Elena RUSYN Autologous stem cell vaccine and methods
EP4269432A1 (en) * 2022-04-26 2023-11-01 Universite de Rouen Normandie Production of therapeutic antibodies by the microalgae phaeodactylum tricornutum
KR20250074841A (ko) * 2023-11-20 2025-05-28 (재) 스크립스코리아항체연구원 키메라 항원 수용체를 발현하는 면역 세포 및 트렙타비딘 스캐폴드 항체 유사 단백질을 포함하는 항암용 조성물, 및 이의 용도

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US20140004127A1 (en) * 2002-10-16 2014-01-02 Medarex, Inc. Human Anti-IFN-gamma Neutralizing Antibodies as Selective IFN-gamma Pathway Inhibitors
WO2019152781A1 (en) * 2018-02-02 2019-08-08 The Trustees Of The University Of Pennsylvania Modified monocytes/macrophages/dendritic cells expressing chimeric antigen receptors and uses in diseases and disorders associated with protein aggregates
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KR20230019419A (ko) 2023-02-08
AU2021251113A1 (en) 2022-10-27
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