JP2023521519A - キメラ抗原受容体を発現し低減した炎症性サイトカインシグナル伝達を有する遺伝子改変された免疫細胞 - Google Patents

キメラ抗原受容体を発現し低減した炎症性サイトカインシグナル伝達を有する遺伝子改変された免疫細胞 Download PDF

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JP2023521519A
JP2023521519A JP2023504152A JP2023504152A JP2023521519A JP 2023521519 A JP2023521519 A JP 2023521519A JP 2023504152 A JP2023504152 A JP 2023504152A JP 2023504152 A JP2023504152 A JP 2023504152A JP 2023521519 A JP2023521519 A JP 2023521519A
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フー，ビリアング
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セレディット エルエルシー
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JP2023504152A 2020-04-06 2021-04-06 キメラ抗原受容体を発現し低減した炎症性サイトカインシグナル伝達を有する遺伝子改変された免疫細胞 Pending JP2023521519A (ja)

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US202063005684P 2020-04-06 2020-04-06
US63/005,684 2020-04-06
PCT/US2021/025906 WO2021207150A1 (en) 2020-04-06 2021-04-06 Genetically modified immune cells expressing a chimeric antigen receptor and having reduced proinflammatory cytokine signaling

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JP2023521519A true JP2023521519A (ja) 2023-05-24
JP2023521519A5 JP2023521519A5 (enExample) 2024-04-12

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US (1) US20230149465A1 (enExample)
EP (1) EP4132973A4 (enExample)
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WO2023060126A1 (en) * 2021-10-06 2023-04-13 Dana-Farber Cancer Institute, Inc. Engineered cytokine receptors for tunable adoptive cell therapy
CN114350665A (zh) * 2022-01-19 2022-04-15 上海优替济生生物医药有限公司 IFN-γ抑制剂及其用途
US20230256065A1 (en) * 2022-02-16 2023-08-17 Elena RUSYN Autologous stem cell vaccine and methods
EP4269432A1 (en) * 2022-04-26 2023-11-01 Universite de Rouen Normandie Production of therapeutic antibodies by the microalgae phaeodactylum tricornutum
KR20250074841A (ko) * 2023-11-20 2025-05-28 (재) 스크립스코리아항체연구원 키메라 항원 수용체를 발현하는 면역 세포 및 트렙타비딘 스캐폴드 항체 유사 단백질을 포함하는 항암용 조성물, 및 이의 용도
CN117965633A (zh) * 2024-04-01 2024-05-03 北京双赢科创生物科技有限公司 一种IFNγ受体敲除的CAR-T细胞的制备方法与应用

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JP2019532970A (ja) * 2016-10-24 2019-11-14 ノビミューン エスアー インターフェロンガンマ関連の適応症を処置または予防するための方法、組成物および投薬レジメン
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