CN115645454A - External cream for treating myopia and preparation method thereof - Google Patents
External cream for treating myopia and preparation method thereof Download PDFInfo
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- CN115645454A CN115645454A CN202211203789.1A CN202211203789A CN115645454A CN 115645454 A CN115645454 A CN 115645454A CN 202211203789 A CN202211203789 A CN 202211203789A CN 115645454 A CN115645454 A CN 115645454A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Abstract
The invention discloses an external cream for treating myopia, which consists of the following components: ganoderma spore powder, glycyrrhrizae radix extract, radix astragali extract, radix Puerariae extract, xanthophyll, horse ointment and snake ointment; the preparation method of the external cream for treating myopia comprises the following steps: step one, evenly spreading the alcohol-extracted ganoderma lucidum spore powder, the liquorice extract, the astragalus extract, the kudzu root extract and the lutein, and sterilizing for 40 minutes by applying 265nm ultraviolet rays. Compared with the prior art, the method has the advantages that: the invention directly reaches the focus by local administration, on the basis, the mixture of animal oil such as horse oil, snake oil and the like is adopted as a matrix, and the traditional Chinese medicine extract is adopted as a formula basis, so that the medicine can be well dissolved in the matrix, can well fit with the skin around the eyes, is quickly absorbed through the skin, and can be quickly absorbed to directly reach the focus.
Description
Technical Field
The invention relates to the technical field of myopia treatment medicines, in particular to an external cream for treating myopia and a preparation method thereof.
Background
With the technological progress, electronic products are full of human life. The incidence of myopia reaches 35.6% for pupils, 71.1% for junior and high school students, 80.3% for high school students, and the whole pupil is in a trend of high, low age and fast development. Along with the increase of myopia people, the myopia degree is deepened, and complications caused by myopia also increase year by year.
Most of the current methods for treating myopia are temporary solution and permanent solution, for example: excimer laser, half femtosecond laser, full femtosecond laser, and the like. Therefore, the myopia treatment method for treating both principal and secondary aspects of disease becomes an urgent problem to be solved in the myopia treatment field.
Disclosure of Invention
The invention aims to solve the technical problem of overcoming the technical difficulties and provides an external cream for treating myopia and a preparation method thereof.
In order to solve the technical problems, the technical scheme provided by the invention is as follows: .
The external cream for treating the myopia comprises the following components: ganoderma spore powder, glycyrrhrizae radix extract, radix astragali extract, radix Puerariae extract, xanthophyll, horse ointment and snake ointment.
The external cream for treating myopia consists of the following components in parts by weight: 20 to 120g of ganoderma lucidum spore powder, 20 to 60g of liquorice extract, 5 to 40g of astragalus extract, 20 to 50g of kudzu root extract, 3 to 10g of lutein, 150 to 450g of horse oil ointment and 50 to 150g of snake oil ointment.
The preparation method of the external cream for treating myopia comprises the following steps:
uniformly spreading the alcohol-extracted ganoderma lucidum spore powder, the licorice extract, the astragalus extract, the kudzu root extract and the lutein, and sterilizing for 40 minutes by applying ultraviolet rays with the wavelength of 265 nm;
step two, taking 1000ml of sterile distilled water, pouring the sterilized ganoderma lucidum spore powder, the sterilized licorice extract, the sterilized astragalus extract, the sterilized radix puerariae extract and the sterilized lutein into the sterile distilled water, stirring until the sterilized ganoderma lucidum spore powder, the sterilized licorice extract, the sterilized astragalus extract, the sterilized radix puerariae extract and the sterilized lutein are completely dissolved, and filtering to remove insoluble impurities;
step three, putting the solution obtained in the step two into a drying box to volatilize water, separating the separated mixture, crushing the mixture by a crusher, and sieving the crushed mixture by a 100-mesh sieve;
step four, mixing the horse ointment and the snake ointment to prepare a matrix, adding the crushed mixture into the matrix, stirring for 25 minutes by using a stirrer at 200 revolutions per second, standing for 4 hours in a sealed manner, and emulsifying uniformly by using an emulsifying machine after the mixture is completely dissolved at the rotation speed of 3200 revolutions per second;
and step five, subpackaging and then applying.
The matrix is prepared by mixing the margarine and the snake oil ointment according to the proportion of 3.
Compared with the prior art, the invention has the advantages that: the invention solves the following problems:
1. the treatment principle is innovative: both traditional and western methods of myopia treatment surround the optical system of the eye for treatment, such as: the correction treatment method mainly aims at optical refraction, wears glasses and changes an optical imaging position; the surgical treatment aims at the treatment of cornea and crystalline lens, and changes the optical imaging position by changing the light refraction; the physical training is mainly to train eye muscles, relax crystalline lenses, change the refractive index of the crystalline lenses and change the optical imaging position; class of drug therapy: the low-concentration atropine also adjusts the optical imaging position by adjusting the pupil size, relaxing crystalline lens; the lutein is used for oral administration and local administration and mainly provides nutrient substances for eye repair; the treatment principle of the traditional Chinese medicine is as follows: the principle is that the blood circulation is promoted, the blood stasis is removed, the liver is cleared and the vision is improved, and aims at the wind wheel, the blood wheel and the water wheel of eyes;
2. the invention innovatively changes the treatment principle, mainly aims at the qi-wheel of eyes, emphatically treats the lung corresponding to the qi-wheel on the basis of inheriting the blood circulation promotion and the blood stasis removal of traditional Chinese medicine, provides the medicines for releasing lung yang and nourishing lung yin, treats the scleral part corresponding to the qi-wheel, improves the blood circulation of the eyes, removes the metabolic wastes of the eyes, improves the internal environment of the eyes and promotes the tissue repair of the eyes through the ganoderma lucidum spore powder extract and the radix puerariae extract, provides liquorice and astragalus membranaceus, tonifies lung qi, nourishes lung yin, recovers the elasticity of the sclera, and ensures that the sclera deforms and recovers the spherical structure of the eyeball by matching with proper eyeball motion training, thereby shortening the axial length of the eyes, imaging the image on the retina and recovering clear vision;
3. the medicine can directly reach the focus by local administration, on the basis, a mixture of animal oil such as horse oil, snake oil and the like is adopted as a matrix, and a traditional Chinese medicine extract is adopted as a formula basis, so that the medicine can be well dissolved in the matrix, can well fit with the skin around the eyes, can be quickly absorbed through the skin, and can be quickly absorbed to directly reach the focus.
Detailed Description
The present invention will be described in further detail with reference to embodiments.
Example 1
The external cream for treating myopia comprises the following components in parts by weight: 20g of ganoderma lucidum spore powder, 20g of liquorice extract, 5g of astragalus extract, 20g of kudzu root extract, 3g of lutein, 150g of horse oil ointment and 50g of snake oil ointment.
The preparation method of the external cream for treating myopia comprises the following steps:
uniformly spreading the alcohol-extracted ganoderma lucidum spore powder, the liquorice extract, the astragalus extract, the kudzu root extract and the lutein, and sterilizing for 40 minutes by using 265nm ultraviolet rays;
step two, taking 1000ml of sterile distilled water, pouring the sterilized ganoderma lucidum spore powder, the sterilized licorice extract, the sterilized astragalus extract, the sterilized radix puerariae extract and the sterilized lutein into the sterile distilled water, stirring until the sterilized ganoderma lucidum spore powder, the sterilized licorice extract, the sterilized astragalus extract, the sterilized radix puerariae extract and the sterilized lutein are completely dissolved, and filtering to remove insoluble impurities;
step three, putting the solution obtained in the step two into a drying box to volatilize water, separating the separated mixture, crushing the mixture by a crusher, and sieving the crushed mixture by a 100-mesh sieve;
step four, taking the horse ointment and the snake ointment, mixing the horse ointment and the snake ointment into a matrix according to the proportion of 3;
and step five, subpackaging and then applying.
Example 2
The external cream for treating the myopia comprises the following components in parts by weight: 120g of ganoderma lucidum spore powder, 60g of licorice extract, 40g of astragalus extract, 50g of kudzu root extract, 10g of lutein, 450g of horse oil cream and 150g of snake oil cream.
The preparation method of the external cream for treating myopia comprises the following steps:
uniformly spreading the alcohol-extracted ganoderma lucidum spore powder, the liquorice extract, the astragalus extract, the kudzu root extract and the lutein, and sterilizing for 40 minutes by using 265nm ultraviolet rays;
step two, taking 1000ml of sterile distilled water, pouring the sterilized ganoderma lucidum spore powder, the sterilized licorice extract, the sterilized astragalus extract, the sterilized radix puerariae extract and the sterilized lutein into the sterile distilled water, stirring until the sterilized ganoderma lucidum spore powder, the sterilized licorice extract, the sterilized astragalus extract, the sterilized radix puerariae extract and the sterilized lutein are completely dissolved, and filtering to remove insoluble impurities;
step three, putting the solution obtained in the step two into a drying box to volatilize water, separating the separated mixture, crushing the mixture by a crusher, and sieving the crushed mixture by a 100-mesh sieve;
step four, taking the equine ointment and the snake ointment, mixing the equine ointment and the snake ointment into a matrix according to the proportion of 3;
and step five, subpackaging and then applying.
The invention is shown in practical application:
100 adult myopia cases are treated, and the myopia cases are randomly divided into a treatment group and a control group, 50 cases respectively, and 100 eyes respectively. Treatment groups: 22 males and 28 females, age 31-57, mean age 39.2, control: 23 male, 27 female, age 29-55 years, average age 37.4 years, and the age, sex and myopia degree of the two groups of patients have no significant difference after statistical treatment. The treatment group administered the cream of the present invention topically to the skin around the eyes (including the outside of the upper and lower eyelids) 3 times a day; the control group applied lutein eye patch to the skin around the eyes 20 minutes each time and 3 times a day. And (3) comparing the results:
and (3) evaluating the curative effect: the two groups of cases are evaluated according to the single eye evaluation effect, the evaluation mechanism is the ophthalmology clinic of people hospital in Huang Ye city, the naked eye vision is detected by a standard visual chart, and the length of the eye axis is measured by the same ophthalmology biological measuring instrument.
TABLE 1
Naked eye vision: and (4) invalidation: the naked eye vision of the standard visual chart is not improved or reduced;
the method has the following advantages: the naked eye vision of the standard visual chart is improved by 1 to 2 rows;
the effect is shown: the standard visual chart improves the naked eye vision by 3 rows and above;
and (3) curing: the standard visual chart can reach 5.0 and above naked eye vision.
By x2 test, the curative effect p of each group is less than 0.05, the result has statistical difference, the significant efficiency p is less than 0.01, and the two groups have significant difference.
TABLE 2
Length of eye axis: and (4) invalidation: no shortening or growth of complex AL;
the method has the following advantages: shortening the composite AL by 0.01-0.05 mm;
the effect is shown: composite AL is shortened by 0.05mm and above;
and (3) curing: composite AL is less than 23.8mm, or 5.0 naked eye vision with axial length <24mm.
By x2 test, the curative effect p of each group is less than 0.05, the result has statistical difference, the significant efficiency p is less than 0.01, and the two groups have significant difference.
The invention and its embodiments have been described above, without this being limitative. Without departing from the spirit of the invention, a person skilled in the art shall appreciate that embodiments similar to the above-described embodiments may be devised without inventing, and the invention shall fall within the scope of the claims.
Claims (6)
1. The external cream for treating myopia is characterized by comprising the following components: ganoderma spore powder, glycyrrhrizae radix extract, radix astragali extract, radix Puerariae extract, xanthophyll, horse ointment and snake ointment.
2. A topical cream for the treatment of myopia according to claim 1, wherein: the external cream for treating myopia comprises the following components in parts by weight: 20 to 120g of ganoderma lucidum spore powder, 20 to 60g of liquorice extract, 5 to 40g of astragalus extract, 20 to 50g of kudzu root extract, 3 to 10g of lutein, 150 to 450g of horse oil ointment and 50 to 150g of snake oil ointment.
3. A topical cream for the treatment of myopia and its preparation method as claimed in claim 2, wherein: the external cream for treating myopia consists of the following components in parts by weight: 20g of ganoderma lucidum spore powder, 20g of liquorice extract, 5g of astragalus extract, 20g of kudzu root extract, 3g of lutein, 150g of horse oil ointment and 50g of snake oil ointment.
4. A topical cream for the treatment of myopia and its preparation method as claimed in claim 2, wherein: the external cream for treating myopia consists of the following components in parts by weight: 120g of ganoderma lucidum spore powder, 60g of liquorice extract, 40g of astragalus extract, 50g of kudzu root extract, 10g of lutein, 450g of horse oil ointment and 150g of snake oil ointment.
5. A method of preparing a topical cream for the treatment of myopia according to any one of claims 1 to 4, wherein the method of preparation comprises the steps of:
uniformly spreading the alcohol-extracted ganoderma lucidum spore powder, the liquorice extract, the astragalus extract, the kudzu root extract and the lutein, and sterilizing for 40 minutes by using 265nm ultraviolet rays;
step two, taking 1000ml of sterile distilled water, pouring the sterilized ganoderma lucidum spore powder, the sterilized licorice extract, the sterilized astragalus extract, the sterilized radix puerariae extract and the sterilized lutein into the sterile distilled water, stirring until the sterilized ganoderma lucidum spore powder, the sterilized licorice extract, the sterilized astragalus extract, the sterilized radix puerariae extract and the sterilized lutein are completely dissolved, and filtering to remove insoluble impurities;
step three, putting the solution obtained in the step two into a drying box to volatilize water, separating the separated mixture, crushing the mixture by a crusher, and sieving the crushed mixture by a 100-mesh sieve;
step four, mixing the horse ointment and the snake ointment to prepare a matrix, adding the crushed mixture into the matrix, stirring for 25 minutes by using a stirrer at 200 revolutions per second, standing for 4 hours in a sealed manner, and emulsifying uniformly by using an emulsifying machine after the mixture is completely dissolved at the rotation speed of 3200 revolutions per second;
and step five, subpackaging and then applying.
6. A method of making a topical cream for the treatment of myopia according to claim 5, wherein: the matrix is prepared by mixing malade and snake oil ointment according to the proportion of 3.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN202211203789.1A CN115645454A (en) | 2022-09-29 | 2022-09-29 | External cream for treating myopia and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202211203789.1A CN115645454A (en) | 2022-09-29 | 2022-09-29 | External cream for treating myopia and preparation method thereof |
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| CN115645454A true CN115645454A (en) | 2023-01-31 |
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| CN202211203789.1A Pending CN115645454A (en) | 2022-09-29 | 2022-09-29 | External cream for treating myopia and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115887561A (en) * | 2023-02-27 | 2023-04-04 | 许梅 | Eye ointment with function of treating eye diseases and production process thereof |
Citations (4)
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| CN101264131A (en) * | 2008-04-30 | 2008-09-17 | 通化力神保健品有限公司 | Chinese medicine extracting liquid eye plaster and preparation thereof |
| CN101946947A (en) * | 2010-09-01 | 2011-01-19 | 佛山市昌荣农业科技有限公司 | Ganoderma lucidum kudzuvine root juice |
| CN104905236A (en) * | 2014-03-11 | 2015-09-16 | 孙钢 | Formula of food-scale health product with effects of radiation damage prevention and repair and eyesight improving |
| CN111000942A (en) * | 2019-12-23 | 2020-04-14 | 四川一只老鹰中医药股份有限公司 | A topical composition for promoting recovery of vision of eye, and its preparation method |
-
2022
- 2022-09-29 CN CN202211203789.1A patent/CN115645454A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264131A (en) * | 2008-04-30 | 2008-09-17 | 通化力神保健品有限公司 | Chinese medicine extracting liquid eye plaster and preparation thereof |
| CN101946947A (en) * | 2010-09-01 | 2011-01-19 | 佛山市昌荣农业科技有限公司 | Ganoderma lucidum kudzuvine root juice |
| CN104905236A (en) * | 2014-03-11 | 2015-09-16 | 孙钢 | Formula of food-scale health product with effects of radiation damage prevention and repair and eyesight improving |
| CN111000942A (en) * | 2019-12-23 | 2020-04-14 | 四川一只老鹰中医药股份有限公司 | A topical composition for promoting recovery of vision of eye, and its preparation method |
Non-Patent Citations (1)
| Title |
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| 尹红;: "复方叶黄素充液胶囊联合复方托吡卡胺滴眼液治疗假性近视44例", 中国药业, vol. 24, no. 03, pages 77 - 78 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115887561A (en) * | 2023-02-27 | 2023-04-04 | 许梅 | Eye ointment with function of treating eye diseases and production process thereof |
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