CN1156215C

CN1156215C - Hand washing and sterilizing agent

Info

Publication number: CN1156215C
Application number: CNB991138546A
Authority: CN
Inventors: 忠孙; 孙忠; 罗鑫龙; 周鸣方
Original assignee: SHANGHAI WHITE CAT CO Ltd
Current assignee: Shanghai Whitecat Shareholding Co., Ltd.
Priority date: 1999-07-07
Filing date: 1999-07-07
Publication date: 2004-07-07
Anticipated expiration: 2019-07-07
Also published as: CN1279888A

Abstract

The present invention relates to a detergent for disinfecting and cleaning hands. The present invention is technically characterized in that the present invention takes organic chlorine and low-carbon chain ethanol as disinfectants, takes fiber, acrylics and cationic polymers as thickening agents, takes potassium hydroxide, steel, ammonia salt, alcohol amine, etc. as neutralizing agents, and comprises humectants and water. All raw materials are mixed and stirred, and are made into the gelatin type disinfectant. Only a little of the present invention is squeezed on hands in use, is uniformly spread, and is automatically volatilized and dried. The present invention does not need water washing, can kill 99.99% of hand bacteria, and has certain destructive effect on hepatitis B HBsAg. Compared with regular liquid detergents for disinfecting and cleaning hands, the present invention has the greatest advantage that the present invention rapidly kills bacteria without water carriers in use, and prevents bacterial cross infection or retransmission.

Description

The sterilization detergent for cleaning hand

The present invention relates to the chemical products field, especially a kind of hand disinfectant.

At present, hand disinfectant commonly used in the daily life is the disinfection hand cleanser of liquid type, and mainly adopting surfactant, disinfectant, thickener, solvent, water is primary raw material.This series products is mainly used in the washroom in family, hotel, uses in the process of washing one's hands, and must wash by water after using, so its use occasion has limited its scope of application.

The object of the present invention is to provide a kind of Disinfection Effect good, good hand touch portably uses conveniently, does not need the sterilization detergent for cleaning hand of water.

Technical scheme of the present invention is: according to the occupation mode of product, the disinfectant of selecting for use and other auxiliary agent use the back in that residue is the least possible on hand, and residue do not influence feel.According to the sterilization requirement of this product, select suitable disinfectant and working concentration, reach the purpose of quick kill bacteria and destruction antigen of hepatitis B virus.Outward appearance according to product reaches transparent jelly shape colloid and uses the requirement of back to feel, selects suitable thickening, neutralizer, humectant.

Its concrete technical scheme is to adopt following raw material and weight percent concentration thereof:

A: alcohol disinfectant 30-90%, it can be a low carbon chain alcohol, also can be ethanol or propyl alcohol or isopropyl alcohol.

B: chlorine class disinfectant: 0.1-5%, it can be chlorophenol or chlorobenzene ethers or its two mixture, as PCMX 2-hydroxyl-4, ' 2 ' 4-three chlorodiphenyl ethers, 2,6-dimethyl-4 monohydroxy chlorobenzene, clorox.

C: animals and plants thickener: 0.1-5%, adopt cellulose family, acrylic compounds, cationic polymer, they can be: the Ka Baibo acrylic resin.

D: neutralizer: 0.1-5% can be potassium hydroxide, sodium hydroxide, ammonium hydroxide or monoethanolamine, diethanol amine, triethanolamine.

E: humectant: 0.5-5% adopts polyalcohol, as medicinal glycerin.

F: deionized water: surplus.

By having adopted alcohols, chlorine class disinfectant among the present invention, make its disinfective action strong, again owing to contain thickener, neutralizer, humectant in the product of the present invention, and one time usage amount is few, the overwhelming majority becomes the effumability material in the prescription, most of component vapors away in the use, and the residue of staying after the use on hand is micro-, and residue is nontoxic.Therefore this product can be crossed water after using, and the adversary does not injure, and can play the effect of preserving moisture on the contrary.

Product of the present invention has stronger disinfective action after testing and did not need the effect of water handguard, and concrete data are as follows:

1, to the killing rate of Pseudomonas aeruginosa (ATCC2027)

Concentration (%)	Difference (min) killing rate % action time
Concentration (%)	Difference (min) killing rate % action time					1	2	5	10
100	100	100	100	100		1	2	5	10
100	100	100	100	100	20	99.65	99.70	99.80	99.83

Annotate: contrast bacterium number is 1.5 * 10 ⁶Cfu/ml

2, to the killing rate of Candida albicans (ATCC1272)

Concentration (%)	Difference (min) killing rate % action time
Concentration (%)	Difference (min) killing rate % action time					1	2	5	10
100	100	100	100	100		1	2	5	10
100	100	100	100	100	20	99.99	99.999	100	100

Annotate: contrast bacterium number is 2.9 * 10 ⁶Cfu/ml

3, to the killing rate of Escherichia coli (8099)

Concentration (%)	Difference (min) killing rate % action time
Concentration (%)	Difference (min) killing rate % action time					1	2	5	10
100	100	100	100	100		1	2	5	10
100	100	100	100	100	20	99.92	99.94	99.98	99.999

Annotate: the contrast bacterium is counted 2.8cfu/ml

4, to the killing rate of staphylococcus aureus (ATCC6538)

Annotate: contrast bacterium number is 1.6 * 10 ⁶Cfu/ml

5, HbsAg failure test:

The concentration of purifying HBxAg is 10ug/ml

Neutralizer: 0.5% sodium thiosulfate+2% Tween-80+0.5% lecithin is to the HbsAg destruction:

Concentration (%)	Difference (min) OD value action time
Concentration (%)	Difference (min) OD value action time					3	5	7	10
100	0.060(+)	0.053(+)	0.045(-)	0.041(-)		3	5	7	10
100	0.060(+)	0.053(+)	0.045(-)	0.041(-)	20	0.518(+)	0.471(+)	0.303(+)	0.183(+)

Negative control OD value 0.022

Positive control OD value 0.286

Sensitivity lng/ml

Good from the visible properties of product of the present invention of above-mentioned data.

Set forth most preferred embodiment of the present invention below:

Implementation column one:

A: ethanol 60%

B: PCMX 0.5%

C: card uncle ripple 941 resins 2%

D: sodium hydroxide 2%

E: medicinal glycerin 5%

F: deionized water surplus

Get final product after above-mentioned thing sample fully mixed.

Embodiment two:

A: isopropyl alcohol 50%

B:2-hydroxyl-4,2 ', 4 ' 1 chlorodiphenyl ethers 1%

C: card uncle ripple 940 resins 3%

D: triethanolamine 1%

E: medicinal glycerin 3%

F: deionized water surplus

Above-mentioned thing sample fully mixed to mix get final product after stirring.

Embodiment three:

A: propyl alcohol 70%

B:2,6-dimethyl-4-hydroxyl chlorobenzene 1.2%

C: card uncle ripple 934 resin fat 3%

D: monoethanolamine 2%

E: the medicinal glycerin chamber is sliding transfers 4%

F: deionized water surplus

Above-mentioned thing sample mixing is fully got final product after the stirring.

Claims

One kind the sterilization detergent for cleaning hand, it is characterized in that its weight percentages of components is:

A. alcohol disinfectant: ethanol or propyl alcohol or isopropyl alcohol 30-90%;

B. disinfectant: PCMX or 2,6-dimethyl-4-hydroxyl chlorobenzene or 2-hydroxyl

-4,2 ', 4 '-three chlorodiphenyl ether 0.1-5%

C. thickener: Ka Baibo acrylic resin 0.1-5%;

D. neutralizer: potassium hydroxide or sodium hydroxide or ammonium hydroxide or monoethanolamine or diethanol amine

Or triethanolamine 0.1-5%;

E. humectant: glycerine 0.5-5%;

F. deionized water: surplus
2, a kind of sterilization detergent for cleaning hand according to claim 1 is characterized in that the Ka Baibo acrylic resin is card uncle ripple 934 resins, card uncle ripple 940 resins, card uncle ripple 941 resins.