CN115607484B

CN115607484B - Plant hair loss preventing and hair nourishing shampoo and preparation method thereof

Info

Publication number: CN115607484B
Application number: CN202211446105.0A
Authority: CN
Inventors: 申宴鹏
Original assignee: Guangdong Mengba Bio Pharmaceutical Co ltd
Current assignee: Guangdong Mengba Bio Pharmaceutical Co ltd
Priority date: 2022-11-18
Filing date: 2022-11-18
Publication date: 2023-04-28
Anticipated expiration: 2042-11-18
Also published as: CN115607484A

Abstract

The invention discloses a plant hair loss prevention hair-growing shampoo and a preparation method thereof, wherein the plant hair loss prevention hair-growing shampoo comprises the following components in parts by weight: 30-60 parts of a plant anti-drop composition; 2-8 parts of an absorbent; 1-10 parts of a surfactant; 3-15 parts of aromatic; 2-10 parts of humectant; 1-8 parts of a thickening agent; 0.1-0.8 part of PH regulator; the invention belongs to the field of shampoo, and relates to the balance of water; according to the invention, the plant extract mixture is used for preparing the hair loss prevention and hair care shampoo, so that the dredging, anti-inflammation and hair regeneration of scalp hair follicles are enhanced, the adsorption capacity of polar keratin in hair fibers is enhanced, the penetration capacity is enhanced, the hydrophobic effect of a lipoprotein layer is enhanced, mao Xiaopi is protected from swelling and falling off, and meanwhile, the hair growth factor VEGF on scalp is stimulated, and the blood circulation is promoted.

Description

Plant hair loss preventing and hair nourishing shampoo and preparation method thereof

Technical Field

The invention belongs to the technical field of shampoo, and particularly relates to a plant hair loss prevention hair-growing shampoo and a preparation method thereof.

Background

Alopecia refers to the phenomenon that hair falls off, normal falling off hair is hair in the withdrawal period and the resting period, and the hair entering the withdrawal period and the hair newly entering the growing period are in dynamic balance continuously, so that normal quantity of hair can be maintained, and pathologic alopecia refers to abnormal or excessive falling off of hair, and the reasons are various, such as androgenetic alopecia, nervous alopecia, endocrine alopecia and nutritional alopecia.

At present, minoxidil tincture is used for external rubbing and finasteride is used for oral administration for treating alopecia, but drug treatment has been proved to have certain side effects on men; more people tend to protect in daily life, and the shampoo is taken as daily necessities which are most contacted with hair, so that the shampoo has certain convenience in solving the problem of alopecia; however, the shampoo for preventing alopecia on the market has uneven effects, for example, the shampoo is prepared by extracting and synthesizing traditional Chinese medicines such as kuh-seng, red sage root, prepared fleece flower root, hairyvein agrimony, bletilla striata, astragalus root and the like in the patent number CN103520036A, and has a certain alopecia preventing function, but the shampoo has long effect time and does not show the persistence of preventing alopecia.

Disclosure of Invention

Aiming at the situation, in order to overcome the defects of the prior art, the invention provides a plant hair loss prevention hair-growing shampoo and a preparation method thereof, and the invention provides the hair loss prevention hair-growing shampoo prepared by using a plant extract mixture, wherein firstly, the black truffle extract improves the adsorption capacity of polar keratin in hair fibers; the shiitake mushroom extract can permeate the CMC layer of Mao Xiaopi; the flos Matricariae Chamomillae extract can protect Mao Xiaopi from swelling and falling off by enhancing the hydrophobic effect of lipoprotein layer; the hibiscus flower extract stimulates a growth factor VEGF related to hair growth on scalp and promotes blood circulation; realizes dredging scalp and hair follicle, diminishing inflammation, promoting hair regeneration, enhancing hair strength and activity, and has lasting effect and no side effect on skin or scalp.

In order to achieve the above purpose, the technical scheme adopted by the invention is as follows: the invention provides a plant hair loss prevention hair growth shampoo which comprises the following components in parts by weight:

30-60 parts of a plant anti-drop composition; 2-8 parts of an absorbent; 1-10 parts of a surfactant; 3-15 parts of aromatic; 2-10 parts of humectant; 1-8 parts of a thickening agent; 0.1-0.8 part of pH regulator; the balance of water.

Preferably, the plant hair loss prevention hair care shampoo comprises the following components in parts by weight:

40-60 parts of a plant anti-drop composition; 4-8 parts of an absorbent; 3-8 parts of a surfactant; 5-15 parts of aromatic; 4-8 parts of humectant; 2-5 parts of a thickening agent; 0.1-0.5 part of pH regulator; the balance of water.

Further, the plant anti-drop composition comprises the following components in parts by weight: 5-10 parts of black truffle extract, 10-20 parts of chamomile extract, 1-10 parts of hibiscus flower extract and 1-8 parts of pholiota nameko extract.

Preferably, the plant anti-drop composition comprises the following components in parts by weight: 6-8 parts of black truffle extract, 15-20 parts of chamomile extract, 4-10 parts of hibiscus flower extract and 3-8 parts of pholiota nameko extract.

Further, the absorbent comprises one or more of laurocapram, propylene glycol and oligomeric arginine chitosan.

Further, the surfactant comprises one or more of disodium cocoyl glutamate and cocoyl glycine, the aromatic comprises one or more of rose essential oil and orange essential oil, the humectant comprises one or more of sorbitol and xylitol, and the thickener comprises sodium chloride and NH ₄ One or more combinations of Cl, the pH adjuster including one or more combinations of citric acid, sodium citrate.

The invention also provides a preparation method of the plant hair-loss prevention hair-growing shampoo, which comprises the following steps:

(1) Pouring the black truffle extract, the hibiscus flower extract, the chamomile extract and the pholiota nameko extract into a stirrer to stir for 2 hours to obtain a mixture 1;

(2) Adding an absorbent, a surfactant, a fragrance, a humectant and deionized water into the mixture 1, stirring in a stirrer, oscillating by using a vibrating motor, and stirring for 2 hours to obtain a mixture 2;

(3) Adding sodium chloride, citric acid and sodium citrate into the mixture 2, and uniformly stirring to obtain the plant alopecia-preventing hair-growing shampoo.

Preferably, the temperature during the stirring is controlled to be 65 ℃ or higher.

Preferably, the vibration frequency of the vibration motor is 350r/min.

The beneficial effects obtained by the invention by adopting the structure are as follows:

according to the invention, the anti-hair loss hair-care shampoo is prepared by using the plant extract mixture, so that the dredging, anti-inflammation and hair regeneration of scalp hair follicles are enhanced, the adsorption capacity and the permeability of polar keratin in hair fibers are improved, the hydrophobic effect of a lipoprotein layer is enhanced, the expansion and the falling of Mao Xiaopi are prevented, and meanwhile, the hair growth factor VEGF on scalp is stimulated, and the blood circulation is promoted.

The invention takes the plant anti-drop composition as the main active ingredient to realize the continuous anti-drop and hair-growing effects.

The black truffle contains rich protein, unsaturated fatty acid, multivitamin, ceramide, triterpene, male ketone, truffle acid, sterol, truffle polysaccharide, truffle polypeptide and other metabolic products, and has extremely high nutrition and health care value; the chamomile has the effects of clearing heat and detoxicating, relieving cough and asthma, dispelling wind-damp, resisting inflammation and resisting bacteria; the hibiscus flower anther has the effects of warming the middle-jiao, eliminating dampness, promoting qi circulation and relieving pain; pholiota nameko has tumor inhibiting effect.

The long-term research of the applicant shows that the plant anti-hair loss composition prepared by the invention has excellent anti-hair loss effect, especially in durability, and can be applied to the preparation of anti-hair loss hair-growing shampoo.

Drawings

FIG. 1 is a graph showing the effect of a plant anti-hair loss hair-growing shampoo on the VEGF concentration of an experimental mouse;

FIG. 2 is a graph showing the effect of a plant anti-hair loss hair-growing shampoo on the DHT concentration of an experimental mouse;

fig. 3 is a graph showing the effect of the plant hair-loss preventing and hair-growing shampoo.

The accompanying drawings are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate the invention and together with the embodiments of the invention, serve to explain the invention.

Detailed Description

The following description of the embodiments of the present invention will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the invention; all other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art. In addition, any methods and materials similar or equivalent to those described herein can be used in the present invention. The preferred methods and materials described herein are illustrative only and should not be construed as limiting the scope of the present application.

The experimental methods in the following examples are all conventional methods unless otherwise specified; the test materials used in the examples described below, unless otherwise specified, were purchased from commercial sources.

Example 1

Plant hair loss preventing and hair nourishing shampoo

The plant hair loss prevention hair-growing shampoo comprises the following components in parts by mass: 40 parts of a plant anti-drop composition; 4 parts of an absorbent; 3 parts of a surfactant; 5 parts of a fragrance; 4 parts of humectant; 2 parts of a thickening agent; 0.1 part of pH regulator; the balance of water.

The plant anti-drop composition comprises the following components in parts by mass: 5 parts of black truffle extract, 10 parts of chamomile extract, 1 part of hibiscus flower extract and 1 part of pholiota nameko extract.

Wherein the absorbent is laurocapram and propylene glycol.

The surfactant is disodium cocoyl glutamate, the aromatic agent is rose essential oil, the humectant is sorbitol, the thickener is sodium chloride, and the pH regulator is citric acid and sodium citrate.

(1) Pouring the black truffle extract, the hibiscus flower extract, the chamomile extract and the pholiota nameko extract in the above parts by mass into a stirrer for stirring for 2 hours to obtain a mixture 1;

Wherein the temperature in the stirring process is controlled to be more than 65 ℃, and the vibration frequency of the vibration motor is 350r/min.

Wherein the black truffle extract, the Hibiscus flower extract, the chamomile extract and the pholiota nameko extract are extracted by adopting an ethanol reflux method.

Example 2

Plant hair loss preventing and hair nourishing shampoo

The plant hair loss prevention hair-growing shampoo comprises the following components in parts by mass: 50 parts of a plant anti-drop composition; 6 parts of an absorbent; 5 parts of a surfactant; 10 parts of a fragrance; 6 parts of humectant; 3 parts of a thickening agent; 0.2 part of pH regulator; the balance of water.

The plant anti-drop composition comprises the following components in parts by mass: 7 parts of black truffle extract, 12 parts of chamomile extract, 5 parts of hibiscus flower extract and 3 parts of pholiota nameko extract.

Wherein the absorbent is laurocapram and propylene glycol.

In addition, the invention also provides a preparation method of the plant anti-hair loss and hair-growing shampoo, which is implemented according to the embodiment 1

Example 3

Plant hair loss preventing and hair nourishing shampoo

The plant hair loss prevention hair-growing shampoo comprises the following components in parts by mass: 60 parts of a plant anti-drop composition; 8 parts of an absorbent; 5 parts of a surfactant; 8 parts of a fragrance; 7 parts of humectant; 4 parts of a thickening agent; 0.3 parts of pH regulator; the balance of water.

The plant anti-drop composition comprises the following components in parts by mass: 10 parts of black truffle extract, 20 parts of chamomile extract, 10 parts of hibiscus flower extract and 8 parts of pholiota nameko extract.

Wherein the absorbent is laurocapram and propylene glycol.

Comparative example 1

This comparative example provides a plant hair-loss preventing shampoo and a method for preparing the same, which is different from example 1 only in that no plant hair-loss preventing composition is contained in all components, and the rest components and the content of the components are the same as example 1.

Experimental example 1

Influence of plant anti-hair loss hair-growing shampoo on experimental mouse endothelial growth factor VEGF and dihydrotestosterone DHT concentration

The experimental example selects adult mice with consistent growth vigor as test objects, randomly divides the mice into 4 groups, and totally 12 mice in each group, and the test specifically comprises the following steps:

(1) Shampoo in example 1, example 2, example 3 and comparative example 1 was used to bathe each group of mice once a day, and back epidermis samples of each group of mice were taken on the 1 st, 4 th, 7 th, 10 th, 13 th, 16 th days of the experiment, and VEGF and dihydrotestosterone DHT concentrations were measured;

(2) Determination of VEGF and DHT concentrations were assayed quantitatively using an ELISA assay.

Analysis of results:

as shown in fig. 1, the VEGF concentration was increased after using examples 1, 2, and 3, the VEGF concentration of example 3 reached the maximum value at day 10, and the VEGF concentration of comparative example 1 was always at a low level.

As shown in fig. 2, the DHT concentrations were reduced after using examples 1, 2, and 3, and the DHT concentration was continuously decreased for 16 days, while the DHT concentration of comparative example 1 was always at a higher level.

Experimental example 2

Application example of plant anti-hair loss hair-nourishing shampoo

4 volunteers with substantially uniform baldness were randomly selected, and the shampoo described in example 1, example 2, example 3 and comparative example was used, respectively, and photographed recording was made on the 5 th day, 10 th day and 15 th day after use.

Analysis of results:

as shown in fig. 3, a is a usage effect diagram of the shampoo of comparative example 1, B is a usage effect diagram of the shampoo of example 1, C is a usage effect diagram of the shampoo of example 2, D is a usage effect diagram of the shampoo of example 3, and left, middle and right are usage effect diagrams of the shampoo of 5 th, 10 th and 15 th days respectively; at 3 time points, no significant change in the number of hair in the volunteers was obtained using comparative example 1, and the number of hair grown was the greatest in the volunteers using example 3; starting on day 5, the volunteers using example 1, example 2 and example 3 began to grow hair, and the number of volunteers using example 3 grew the most.

Experimental example 3

Evaluation of effect of plant hair-loss prevention hair-growing shampoo

20 volunteers were selected for this test, randomized into 4 groups, each group of volunteers were each treated daily with shampoo from example 1, example 2, example 3 and comparative example 1, respectively, and after 2 weeks of continuous testing, were left for 2 weeks, and were rated reasonably.

Analysis of results:

as shown in table 1, 20 volunteers evaluated the effects of the shampoo of example 1, example 2, example 3 and comparative example 1 after use, wherein the evaluation of comparative example 1 after continuous use for 2 weeks was no effect on hair loss prevention, and the evaluation of comparative example 1 after stopping use for 2 weeks was no effect on hair loss prevention; example 1 was evaluated as producing a large amount of effects on hair loss prevention after 2 weeks of continuous use, and as producing only a partial effect after 2 weeks of discontinuation of use; example 2 was evaluated as having a good effect on hair loss prevention after 2 weeks of continuous use, and as having a large effect on hair loss prevention after 2 weeks of discontinuation; example 3 was evaluated as good for preventing hair loss after 2 weeks of continuous use, and was still good for preventing hair loss after 2 weeks of discontinuation, indicating that the plant hair-growing shampoo of example 3 had the best effect for preventing hair loss and lasted for a longer period of time.

Table 1 evaluation results of the effects of the plant anti-alopecia and hair-growing shampoo

Note that: "- -" means no effect; "-" means that a weak effect is produced; "-" means that a small amount of effect is produced; "+". ++'s representation of good effect is produced; "++" means that a large number of effects are produced; "+" indicates that a partial effect is produced.

Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

The invention and its embodiments have been described above with no limitation, and the actual construction is not limited to the embodiments of the invention as shown in the drawings. In summary, if one of ordinary skill in the art is informed by this disclosure, a structural manner and an embodiment similar to the technical solution should not be creatively devised without departing from the gist of the present invention.

Claims

1. A plant hair-loss preventing hair-growing shampoo is characterized in that: the plant hair loss prevention hair-growing shampoo comprises the following components in parts by weight: 30-60 parts of a plant anti-drop composition; 2-8 parts of an absorbent; 1-10 parts of a surfactant; 3-15 parts of aromatic; 2-10 parts of humectant; 1-8 parts of a thickening agent; 0.1-0.8 part of pH regulator; the balance of water is used for preparing the water,

the plant anti-drop composition comprises the following components in parts by weight: 5-10 parts of black truffle extract, 10-20 parts of chamomile extract, 1-10 parts of hibiscus flower extract and 1-8 parts of pholiota nameko extract.

2. The plant hair loss preventing and growing shampoo according to claim 1, wherein: the plant hair loss prevention hair-growing shampoo comprises the following components in parts by weight: 40-60 parts of a plant anti-drop composition; 4-8 parts of an absorbent; 3-8 parts of a surfactant; 5-15 parts of aromatic; 4-8 parts of humectant; 2-5 parts of a thickening agent; 0.1-0.5 part of pH regulator; the balance of water.

3. The plant hair loss preventing and growing shampoo according to claim 1, wherein: the plant anti-drop composition comprises the following components in parts by weight: 6-8 parts of black truffle extract, 15-20 parts of chamomile extract, 4-10 parts of hibiscus flower extract and 3-8 parts of pholiota nameko extract.

4. The plant hair loss preventing and growing shampoo according to claim 1, wherein: the absorbent comprises one or more of laurocapram, propylene glycol and oligomeric arginine chitosan.

5. The plant hair loss preventing and growing shampoo according to claim 1, wherein: the surfactant comprises one or more of disodium cocoyl glutamate and cocoyl glycine.

6. The plant hair loss preventing and growing shampoo according to claim 1, wherein: the aromatic comprises one or more of rose essential oil and orange essential oil.

7. The plant hair loss preventing and growing shampoo according to claim 1, wherein: the humectant comprises one or more of sorbitol, xylitol.

8. A plant anti-drop fertility according to claim 1The hair shampoo is characterized in that: the thickener comprises sodium chloride and NH ₄ One or more of Cl.

9. A method for preparing the plant hair loss prevention and hair growth promoting shampoo according to any one of claims 1 to 8, which is characterized in that: the method specifically comprises the following steps:

(1) Pouring the black truffle extract, the hibiscus flower extract, the chamomile extract and the pholiota nameko extract into a stirrer for stirring for 2 hours to obtain a mixture 1;

(3) And adding a thickening agent and a pH regulator into the mixture 2, and uniformly stirring to obtain the plant alopecia-preventing hair-growing shampoo.