KR101705853B1 - Production method and compositions of the hair restorer in pharmaceutical plants - Google Patents

Abstract

The present invention relates to a method for producing a hair growth agent produced by medical plants. More specifically, the method comprises: a preparing step of collecting and sorting good state medicinal plants; a drying step of drying sorted medicinal plants; a pulverizing step of pulverizing the dried medicinal plants; an extracting process and antibacterial process performing step of mixing powder generated by the pulverizing step with water, and heating a mixture, and making the mixture antibacterial; a sterilizing step of irradiating gamma rays onto an extract, and sterilizing the extract; an adding and emulsifying step of adding and mixing additional raw ingredients in the sterilized extract; and a second antibacterial process performing step of performing preservative treatment. In a production step, a composition is heated at a low temperature, and thus thermal destruction is minimized. In addition, bodily waste in pores is removed, and a blood circulation is improved. Thus, nutrients needed for hair roots are supplied, and the hair roots are stimulated, so hair growth is promoted and the hair roots are strongly maintained.

Description

TECHNICAL FIELD The present invention relates to a method for producing a hair growth inhibitor,

The present invention relates to a method for producing a hair growth product made of a medicinal plant, and more particularly, to a method for producing a hair growth product, which comprises preparing a medicinal plant having a good condition, An extracting step and an antibacterial treatment step in which water is mixed with the powder produced by the pulverizing step and heated and antibacterial treatment is carried out, a sterilization step in which the extract is sterilized by irradiation with gamma rays, and an additional raw material is added to the sterilized extract And a secondary antibacterial treatment step of emulsifying and preserving the hair.

In modern society, hair loss is rapidly increasing due to increased pollution, genetic variation, and stress. The domestic bald population is 12% of the total population and it is estimated that 20% of adult men are bald. In addition, about 880,000 people, 5% of the total population, are women, and in recent years, baldness in their 20s and 30s has been increasing.

The major causes of hair loss are stress, obesity due to dietary changes, hair follicles including seborrheic scalp, perm and staining, and stress, dietary life, and aging can affect the progress of hair loss, Even if there is no person or genetic predisposition, the effect is small before puberty.

The cause of hair loss in addition to the above genetic inheritance or hormone imbalance is caused by an abnormality of the autonomic nervous system which occurs in the endocrine system abnormality due to scalp tension, blood circulation disorder, mental stress, nutritional imbalance, excessive smoking, excessive drinking and irritation or contaminated food intake , Circulatory disorders such as blood circulation disorder, and excessive secretion of male hormones.

The development of a common hair growth promoter has been shown to be effective in promoting the activation of hairy cells, promoting blood circulation of hair follicle cells, inhibiting sebum secretion, inhibiting male hormone conversion, and promoting the transition from the growth phase to the regenerating / (Transforming growth factor-β1). However, it is difficult to verify the effects of hair growth and its components. It is a method of extracting hot water components by mixing various materials. It is inevitable to break down and it is difficult to extract the extremely fine low-molecular substance which can directly supply the nutrients to the pores.

In addition, the above-described hair growth promoter and hair transplantation surgery have a limited range of use, and it is difficult to fundamentally treat hair loss, and may accelerate the production of scalp or sebum, thereby further exacerbating the symptoms of hair loss.

Prior art of hair growth using medicaments is disclosed in Korean Patent No. 10-1219239 (Dec. 31, 2012), which is a method of producing a hair growth promoting agent, which comprises extracting Sasa extract, A mixture of 4 g of mint extract and 1 to 1.4 g of omija extract was mixed with 100 g of water to prepare a pressurized hot water pot, A second step of producing a second molten metal by pressurizing the molten metal at room temperature and a second step of preparing a second molten metal by weight of 200 g of the first molten metal produced by the first step produced by the first step, And a filtration step in which the mixture mixed by the mixing step is put in a pressure boiler, and the mixture is stirred and filtered.

Korean Patent No. 10-0668878 (2007. 01. 08.) relates to a composition for hair growth, composition for external application for hair growth and composition for hair growth, composition for external application for hair growth, Adding ethanol as an extraction solvent in a weight ratio of 1: 6 to ginseng, red pepper and common sugar, and immersing the mixture at room temperature for 7 days to obtain an ethanol extract; Purified water is used as an extraction solvent in 1: 9, 1, 2, 3, 4, 5, 6, And distilling the mixture to obtain a distillate extract; And mixing the ethanol extract at a constant weight ratio.

The above-mentioned prior arts also have a problem that it is difficult to verify the hair growth effect, and that the composition is too much to be manufactured and is difficult to manufacture, and it is known that the hair growth effect due to the influence of a composition on the hair growth efficiency due to the combination of the respective constituents none.

Korean Registered Patent No. 10-1219239 (December 31, 2012) Korean Registered Patent No. 10-0668878 (2007.01.08)

The present invention has been made to overcome the problems of conventional hair removal and hair transplantation and wigs caused by hair loss, and it has been found out that the medicinal plants such as Hashuo, Lactobacillus, Astragalus, Hanxiku, Angelica gigas, The present invention provides a method for producing a hair growth agent, which comprises the steps of: extracting components useful for hair growth and hair growth using a composition of the present invention;

In order to solve the above-mentioned problems and to achieve the object, a method for producing a hairy product made of a medicinal plant of the present invention comprises the steps of: a) collecting and extracting hwaseo, mackerel, cilantro, Preparation phase;

b) drying the selected medicinal plants after washing;

c) milling the dried medicinal plant to 100-200 mesh to produce a powder;

d) an extraction step and an antibacterial treatment step of mixing the pulverized powder with water, followed by primary and secondary hot water extraction and antibacterial treatment;

e) a sterilization step of sterilizing the extraction process and the antibacterially-treated extract by irradiating gamma rays;

f) adding and emulsifying the sterilized extract by adding an additional raw material and mixing the mixture with an emulsifier; And

and g) a secondary antibacterial treatment step of performing a secondary antibacterial treatment on the added and emulsified treatment liquid.

In the extraction step and the antibacterial treatment step, water and medicinal plant are blended in a weight ratio of 1: 4 to 1: 7.5.

The first extraction step is performed at 55 to 65 ° C, 0.7 to 1.3 atm and 7 to 9 hours. The second extraction step is performed at 75 to 85 ° C, 1.7 to 2.3 atm, 7 to 9 hours.

The antimicrobial treatment in the extraction step and the antibacterial treatment step is carried out by adding 1 to 3% by weight of ethylhexanediol to the extracted liquid after the completion of the first extraction step.

The sterilization step is performed by irradiating the extraction solution and the extract solution with an irradiation dose of 10 to 50 kGy by a gamma ray.

The second antimicrobial treatment step adds a preservative to the sterilized extract.

The hair growth agent is 20 to 30% by weight of seaweed, 10 to 15% by weight of pine kernel, 5 to 10% by weight of oriental herb, 10 to 15% by weight of oriental herb, 10 to 15% 5 to 10% by weight of white paper, and 1 to 3% by weight of white paper.

And 0.1 to 10% by weight of D-panthenol, salicylic acid, L-menthol, nicotinamide and biotin in the pharmaceutical plant of the hair growth promoter.

1 is a process diagram of a method for manufacturing a hair growth product made from a medicinal plant according to the present invention.

The name of the present invention is "a method for producing a hair growth product made from a medicinal plant and a composition thereof ", and a detailed description thereof will be omitted so as to be easily known to a person skilled in the art. . The terms defined in this specification and claims should not be construed as limiting the scope of the present invention and should be construed in accordance with the intentions and relationships of the operator and should be construed as meaning and concept consistent with the technical idea of the present invention.

In one aspect of the present invention,

The method for producing the hair growth inhibitor further mixed with the medicinal plant

a) preparatory stage for picking and picking out seaweed, livestock meat, celestial gypsum, hansukscho, angelica, hyacinthae, manganese, white and black;

b) drying the selected medicinal plants after washing;

c) milling the dried medicinal plant to 100-200 mesh to produce a powder;

d) an extraction step and an antibacterial treatment step of mixing the pulverized powder with water, followed by primary and secondary hot water extraction and antibacterial treatment;

e) a sterilization step of sterilizing the extraction process and the antibacterially-treated extract by irradiating gamma rays;

f) adding and emulsifying the sterilized extract by adding an additional raw material and mixing the mixture with an emulsifier; And

and g) a secondary antibacterial treatment step of subjecting the added and emulsified treatment liquid to a secondary antibacterial treatment.

Hereinafter, a method for manufacturing a hair growth product made from a medicinal plant according to the present invention will be described in detail with reference to the drawings.

1 is a process diagram of a method for manufacturing a hair growth product made from a medicinal plant according to the present invention.

(B) drying step (S20), (c) pulverizing step (S30), (d) extraction step and antibacterial treatment step (S40), e (S50), f) addition and emulsification step (S60), g) secondary antibacterial treatment step (S70).

a) Preparation step (S10) is a step of collecting and selecting a medicinal plant, wherein the medicinal plant comprises 20 to 30% by weight of Hashuo, 10 to 15% by weight of pectin, 5 to 10% 15 to 20% by weight of Angelica keiskei koidz., 10 to 15% by weight of papaya, 5 to 10% by weight of papaya, 5 to 10% by weight of white paper and 1 to 3% by weight of paprika.

In the above medicinal plants, the leaves are collected from autumn to spring, the leaves and stems are picked up from time to time, the leaves of the leaves are collected in spring and autumn, and the fruits are collected in autumn The mature seeds of the lotus are dried, the rootstock is used to dry the rootstocks, the myrtle leaves and the perfume fragrance are collected from time to time, the molds are dried after picking the ripe berries in the autumn, Collect the soil at the end before freezing.

Also, it is preferable to collect the soil from a place where it is not polluted, and to use it mainly for those with good mouth and stem condition, especially good roots.

The composition of the above-mentioned sewage is composed of nitrogen, fat, mint, lecithin and water-soluble substance and has the effect of tonic, gangjeong, blood, interpolation, It is used as a remedy for germanium. Especially, kidney function is improved, so hair is not whitened, and it has an effect on hair loss symptoms.

The above-mentioned meat of livestock is excellent in the mulmungjeol, wells, hematemesis and uterine hemorrhage, dyspepsia and dysentery, and enhances the function of the kidneys in particular, as in the case of diarrhea.

It is used for the treatment of headache, anemia, and women's diseases such as calm, pain, and tenderness. It is taken in July and August, but it is dried by removing the hairy root.

The leaf is the young branch and leaves of the periwinkle tree and the relative plants of the periwinkle, which is an evergreen needle tree belonging to the Quercus mongolica family. It has a stem cell factor, which is a cytokine that plays an important role in hair growth, (SCF).

Other types of Yeongdyeong, Baekjimman, and Hansikwi are also effective to prevent hair loss.

b) In the drying step (S20), the selected medicinal plants are washed and dried, and the first rinsing is carried out in which water, soil, sand and dust are washed, and second rinsing is performed in the same manner as the first rinsing. Wash with running water. At this time, it is desirable to prevent damage to the root roots.

In addition, the medicinal plant is dried to naturally drying to reduce the drying cost by removing the cellulose and increasing the extraction efficiency of the active ingredient.

c) In the pulverization step (S30), the dried medicinal plants are pulverized into 100 to 200 mesh to prepare powders, and the respective compositions are mixed.

d) In the extraction step and the antibacterial treatment step (S40), the mixing ratio of water and the medicinal plant powder is 1: 4 to 1: 7.5 in the extraction step and the antibacterial treatment step, The primary extraction is carried out at 55 ~ 65 ℃, 0.7 ~ 1.3 atm and 7 ~ 9 hours. The secondary extraction is carried out at 75 ~ 85 ℃, 1.7 ~ 2.3 atm, 7 ~ 9 hours, After completion of the first extraction step, 1 to 3% by weight of ethylhexanediol is added, followed by a second extraction step.

e) In the sterilization step (S50), the extraction step and the extract solution which has been subjected to antibacterial treatment are sterilized by irradiating gamma rays at a dose of 10 to 50 kGy.

f) In the addition and emulsification step (S60), an additional raw material is added to the sterilized extract and mixed using an emulsifier.

The raw material and the content to be added are 1 to 5% by weight of D-Panthenol, 02 to 0.5% by weight of salicylic acid, 1 to 5% by weight of L-menthol, 1 to 4% by weight of nicotinamide, 0.01 to 0.8% .

The D-panthenol improves skin penetration and hydration, and itchy skin and fever relief.

Salicylic acid is extracted from willow bark and helps dissolve keratin, beads, acne and sebum.

The L-menthol is extracted from willow bark in the same manner as salicinic acid and has vasoconstriction, sedation, itching, inflammation and sterilization.

The nicotinamide inhibits moisture loss, stimulates the microcirculation of the dermis, promotes the secretion of collagen and inhibits sebum.

The biotin is one of the necessary vitamin B complexes in the body to prevent the occurrence of dermatitis, limb paralysis and alopecia.

g) In the second antibacterial treatment step (S70), the preservative is added to the sterilized extract.

The above-mentioned preservative is added in an amount of less than 0.4% by weight of parabene to the extract prepared through the addition and emulsification step (S60). Alternatively, one of natural preservative lavender, tea tree and mugwort extract may be selected and used as a preservative.

In a further aspect,

The medicinal plant may be added with dried persimmon and licorice, wherein the dried persimmon is added in an amount of 3 to 6 wt% and the licorice is added in an amount of 1 to 3 wt%. The main ingredient of the dried persimmon is iridoid and saccharide, Anti-allergy, inhibition of bacterial growth, and inhibition of 5α-reductase activity.

Meanwhile, the extract and the yeast extracted after the second hot water extraction process are mixed at a weight ratio of 7: 3, and then fermented for 6 to 8 days to produce a high concentration extract to enhance the effect. In this case, It is preferable to use yeast (yeast) to be used.

< Example >

Hereinafter, the present invention will be described more specifically by the following representative examples, but the present invention is not limited in any way by these embodiments.

Example  : Manufacture of hair growth products made from medicinal plants

After washing and drying, the seeds were pulverized to 200 mesh, and seeded with 23% by weight of salted, 11% by weight of pine kernel, 7% by weight of pine seedlings, The mixing ratio of the water and the mixed powder was 1: 1, and the mixing ratio of the water and the mixed powder was 1: 5, the primary extraction was carried out at 55 ° C and 1 atm for 8 hours. After the addition of 3% by weight of ethylhexanediol, the secondary extraction was carried out at 75 ° C and 1.8 atm for 7 hours. , And the mixture was sterilized by adding an additional raw material, mixed with an emulsifying agent, and then subjected to a secondary antibacterial treatment with a preservative.

Test Example  : Clinical trials of hair growth products made from medicinal plants

Male patients with the diagnosis of androgenetic alopecia aged 22 to 54 years were used 3 times a day for 2 weeks to 16 weeks. The hair was sprayed to about 2 cm of scalp area, massaged while spraying the injection site, and consumed 3 ml once .

The following table shows changes in the number of hairs and hair diameter per photo and period.

0 weeks 8 weeks 16 weeks Number of Hair (n / cm2) 65 81 96 Hair diameter (mm) 0.079 0.082 0.087

The number of hairs increased to 96 after 65 to 16 weeks of hair growth and the diameter of hair also ranged from 0.079 to 0.087, stimulating the scalp by the hair growth agent made from the medicinal plant, By expressing healthy hair, hair loss was prevented and the effect of hair growth was demonstrated.

The method of using the hair growth agent produced by the above-described production method is as follows: 1) The hair growth agent should not be sprayed on hair (hair); 2) Hair loss region Spray about 2cm of each side of the scalp. (It is because the pores around the scalp and the hair (hair) around the scalp are thinned, and the hair of the hair loss part scalp is thicker, and the hair of the hair loss part is more likely to concede.) 3) After spraying the product, Massage the sprayed area with a tap. 4) It is absorbed in the scalp for about 7 minutes.

Use volume: i) 100ml standard use period: 2 weeks (14 days) ⅱ) 3 times daily morning, lunch and evening ⅲ) Usage amount per injection: about 3ml (amount to be used varies depending on hair loss region, Most of all, 100ml dose is used in about 2 weeks.) Iv) Prevention of hair loss and wool effect is accelerated if it is applied frequently.

As described above, the method of manufacturing a hair growth inhibitory composition of the present invention can minimize the heat destruction by heating the composition at a low temperature during the manufacturing process. Further, by removing waste materials and improving blood circulation inside the pores, Stimulates hair growth and maintains the hair roots firmly.

While the present invention has been described in connection with certain exemplary embodiments and drawings, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, Various modifications and variations are possible.

Claims (8)

In a hair growth inhibitor prepared from a medicinal plant,
The method for producing the hair growth agent
a) preparatory stage for picking and picking out seaweed, livestock meat, celestial gypsum, hansukscho, angelica, hyacinthae, manganese, white and black;
b) drying the selected medicinal plants after washing;
c) milling the dried medicinal plant to 100-200 mesh to produce a powder;
d) an extraction step and an antibacterial treatment step of mixing the pulverized powder with water, followed by primary and secondary hot water extraction and antibacterial treatment;
e) a sterilization step of sterilizing the extraction process and the antibacterially-treated extract by irradiating gamma rays;
f) adding and emulsifying the sterilized extract by adding an additional raw material and mixing the mixture with an emulsifier; And
g) a secondary antibacterial treatment step of performing a secondary antibacterial treatment on the added and emulsified treatment liquid,
The antibacterial treatment in the extraction step and the antibacterial treatment step is carried out by adding 1 to 3% by weight of ethylhexanediol to the extracted liquid after the completion of the first extraction step,
Wherein the additional raw material comprises 0.1 to 10% by weight of D-panthenol, salicylic acid, L-menthol, nicotinamide and biotin,
In the secondary antibacterial treatment step, a preservative is added to the sterilized extract, and the preservative is added with 0.4% by weight of paraben, or one of natural preservative lavender, tea tree and mugwort extract is used as a preservative,
Wherein the extract and the yeast extracted after the second hot water extraction step are mixed at a weight ratio of 7: 3 and then fermented for 6 to 8 days. The method according to claim 1,
Wherein the mixing ratio of water and the medicinal plant powder is 1: 4 to 1: 7.5 by weight in the extraction step and the antibacterial treatment step. The method according to claim 1,
The first extraction step is performed at 55 to 65 ° C, 0.7 to 1.3 atm and 7 to 9 hours. The second extraction step is performed at 75 to 85 ° C, 1.7 to 2.3 atm, 7 to 9 hours. &Lt; RTI ID = 0.0 &gt; 8. &lt; / RTI &gt; delete The method according to claim 1,
Wherein the sterilization step comprises sterilizing the extract solution obtained by the extraction process and the antibacterial treatment solution with a dose of 10 to 50 kGy by irradiation with gamma rays. delete The method according to claim 1,
The hair growth agent is 20 to 30% by weight of seaweed, 10 to 15% by weight of soft meat, 5 to 10% by weight of cinnabar, 10 to 15% by weight of hanjichecho, 15 to 20% by weight of Angelica giganta, 10 to 15% , 5 to 10% by weight of white paper, 1 to 3% by weight of medicinal plants and an additional raw material. delete

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