KR101629542B1 - method for extracting hair growth promoting components - Google Patents

Abstract

The method for extracting the hair growth promoting component of the present invention comprises the steps of (1) 15 parts by weight of green tea, 17 parts by weight of gossyphea, 17 parts by weight of red ginseng, 17 parts by weight of dried jujube, 12 parts by weight of sulfur, 12 parts by weight of Angelica keiskei, 2 parts by weight of almonds and 200 parts by weight of purified water were mixed in 7 parts by weight of plantain, and the mixture was heated in a pressure vessel at 120 캜 for 1 hour and 30 minutes to extract the mixture.
(2) The extracted aqueous solution is spontaneously cooled to room temperature while keeping the cap of the pressure vessel open to obtain an extract in which the volatile components have been removed; And
(3) separating the solids and the liquid components from the extract liquid from which the volatile substances have been removed by using a marginal cloth, and extracting the liquid components by squeezing the solids using the rods.

Description

[0001] The present invention relates to a method for extracting hair growth promoting components,

The present invention relates to a method for extracting a hair growth promoting component.

The cause of hair loss is diverse, and genetic factors and excessive secretion of androgens, the male hormone, are thought to be responsible for baldness. There are also alopecia due to autoimmune diseases and alopecia due to severe stress such as endocrine disease, nutritional deficiency and drug use. In recent years, hair loss has become more prominent not only in the elderly but also in younger age groups due to erroneous eating habits, stress, frequent firming, and dyeing.

Minoxidil, which is currently used as a hair growth promoter, and Propecia, a form of taking it, are used as remedies. In the case of resting alopecia, treatment of the cause is important because the symptoms of alopecia are recovered.

Minoxidil was developed as a treatment for hypertension that enlarged blood vessels in the past, but it was developed as a hair loss treatment agent in the light of the hairy side effects on the forehead and the back of the hand. The mechanism of action of minoxidil is unclear, but theoretically it is known to expand the blood vessels of the scalp and open the calcium channels of the cell membrane to supply oxygen, blood and nutrients to hair follicles to thicken the hair. It is also more effective for people who have symptoms of hair loss less than 5 years and has a large hair growth effect on the crown. At the beginning of the treatment, hair loss phenomenon called 'shedding' may occur, but the use of the drug may be continued because the response to the drug is good. However, there is a side effect that hair growth can not occur after the shedding phenomenon very rarely, and side effects such as rash, inflammation, itching, and hairs in other parts other than the scalp are developed at the area where minoxidil is applied.

Propecia, which is sold by Merck, is a finasteride that has been developed to treat hyperplasia of the prostate, but has been used to treat hair loss after finding that hair growth is promoted after taking it . Testosterone is converted to dihydrotestosterone (DHT), the major component that causes hair loss by 5α-reductase. Finasteride inhibits this 5α-reductase and reduces the concentration of DHT that causes hair loss. Typical side effects are erectile dysfunction such as erectile dysfunction, libido, dizziness, headache, swelling and skin rash. In addition, there is a risk of birth defects when taking the drug can not be prescribed to women.

These remedies for hair loss are limited to women, and side effects related to male hormones and the problem that hair loss is resumed if they stop taking them.
Patent literature
Korean Patent Registration No. 10-0762413 (Registration date: September 20, 2007)
Korean Patent Registration No. 10-0755983 (Registered Date: Aug. 30, 2007)

Accordingly, a first problem to be solved by the present invention is to provide a method of extracting components having a harmful effect on the human body by using harmful herbicidal ingredients to reduce adverse effects on the human body, and to prevent hair loss and promote hair growth.

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(1) 15 parts by weight of green tea, 17 parts by weight of gossyphea, 17 parts by weight of red ginseng, 17 parts by weight of dried jujube, 12 parts by weight of sulfur, 12 parts by weight of Angelica gigas, 12 parts by weight of mugwort 12 2 parts by weight of almonds and 200 parts by weight of purified water were mixed in 7 parts by weight of plantain, and the mixture was heated in a pressure vessel at 120 캜 for 1 hour and 30 minutes to extract the mixture.
(2) The extracted aqueous solution is spontaneously cooled to room temperature while keeping the cap of the pressure vessel open to obtain an extract in which the volatile components have been removed; And
(3) Extracting solids and liquid components from the extract liquid from which the volatile substances have been removed using a hemp cloth, extracting the liquid components by squeezing solids using a rod, and extracting the hair growth promoting component ≪ / RTI >

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The hair growth promoting component of the present invention has no adverse effect on the human body due to the use of herbal medicine components and has excellent hair growth effect by the pharmacological effect and antagonistic effect of each ingredient. In addition, the hair growth promoting method of the present invention can effectively penetrate into the pores by spreading the pores on the scalp in accordance with the hot pepper seed ingredient.

FIG. 1 shows a process for producing the hair growth promoting component of the present invention in sequence.
FIG. 2 is a step-by-step representation of the hair growth promoting method of the present invention.
FIGS. 3, 4 and 5 are photographs showing the effect of the hair growth promoting method of the present invention.

The method for producing the hair growth promoting component of the present invention comprises the steps of: (1) 15 parts by weight of green tea, 17 parts by weight of gossyphea, 17 parts by weight of red ginseng, 17 parts by weight of dried jujube, 12 parts by weight of sulfur, 12 parts by weight of Angelica keiskei, 2 parts by weight of almonds and 200 parts by weight of purified water were mixed in 7 parts by weight of plantain, and the mixture was heated in a pressure vessel at 120 캜 for 1 hour and 30 minutes to extract the mixture.
(2) The extracted aqueous solution is spontaneously cooled to room temperature while keeping the cap of the pressure vessel open to obtain an extract in which the volatile components have been removed; And
(3) separating the solids and the liquid components from the extract liquid from which the volatile substances have been removed by using a marginal cloth, and extracting the liquid components by squeezing the solids using the rods.

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The green algae which are the raw materials of the extract ingredients contained in the composition of the present invention are collectively referred to as the keratinized horns of various deer such as the carob, plum rust or dainok belonging to the deer (Cervidae). It promotes blood circulation, eliminates eosinophilia, and helps with kidney function and liver function. It also contains a large amount of calcium to strengthen the bones, which is effective in promoting the growth of children.

The raw material of the extract ingredients contained in the composition of the present invention is the root bark and stem skin of Acanthopanax sessiliflorum or other equine plants (Araliaceae). It is a medicinal plant and is used as neuralgia, arthritis, hypertension, nervous breakdown, diabetes and tonic. The main component of the gingiva is the treiterpenoid-based glycoside, eleutheroside A to G. In addition, syringin is good for fatigue recovery, and sterol and coumarin are effective for blood pressure lowering. All parts of roots, stems, leaves, fruits and flowers of the gooseberry can be used for medicinal purposes, but it is preferable to use roots or stem shells.

Red ginseng, which is a raw material of the extract ingredients contained in the composition of the present invention, is produced by roasting ginseng root ( Panax ginseng, Araliaceae and Araliaceae) and has effects such as fatigue recovery, diabetes treatment, osteoporosis prevention and immunity enhancement. Saponin contained in red ginseng is a typical chemical component of ginseng, and it contains various kinds of saponin. Depending on the kind of saponin, various kinds of pharmacological actions such as anti-diabetes, immunoregulation, improvement of memory decline and anti-cancer effect are exhibited. In addition to saponin, it contains various components such as carbohydrates, phenol compounds and nitrogen compounds.

The dried jujube that is the raw material of the extract ingredients contained in the composition of the present invention refers to dried fruits of the jujube ( Zizyphus jujuba, Raglanae and Rhamnaceae). Dried jujube has efficacy for diuretic, tonic, emollient, nervous breakdown, anemia, poor appetite and cold sores. In addition, it contains vitamin B, vitamin C, saponin, calcium and other pharmacological ingredients. Beta carotene is effective in preventing aging by removing active oxygen in the body.

Astragalus membranaceus , which is a raw material of the extract components contained in the composition of the present invention, It is the root part of the Hwanggi which belongs to the leguminosae, and it is removed as it is. Hwanggi is a medicinal product which is prescribed for the weakness of the body, boredom of fatigue, bloody bloom, built-in sewage, and cold sweat. The roots of Hwanggi include formononetin, betaine, cholin, and isoliquiritigenin, which acts as an antimicrobial. GABA (amino acids) γ-aminobutyric acid).

Angelica gigas , which is a raw material of the extract ingredients contained in the composition of the present invention, belongs to the mountain type (Umbelliferae), and herb medicine refers to its roots. The Angelica gigas have blood circulation that circulates the blood smoothly and blood that produces blood, and it is excellent in anticancer effect and blood pressure lowering effect. The main component of the root is decanamin, a pyranocoumarin substance, which lowers blood pressure and has a strong pharmacological action against the uterus. In addition, it contains umbelliferone, β-sitosterol, nodakenetin and others.

Artemisia princeps , which is a raw material of the extract ingredients contained in the composition of the present invention, is a composite plant, and is used as abdominal pain, soil, and hemostatic agent, and is effective for cold menstrual irregularity and uterine bleeding. The flavonoid component of mugwort is effective in detoxifying the liver and helps to regain fatigue. The tannin component inhibits the production of lipid peroxides, which is effective in preventing aging of cells.

The almond ( Prunus amygdalus ), which is a raw material for the extract ingredients contained in the composition of the present invention, is a plant belonging to the rose family, and the seed contained in the flesh is edible. The shells of the seeds contain a polyphenol-based resveratrol component that lowers cholesterol levels and an unsaturated fatty acid, oleic acid.

The herbal medicine extracts contained in the composition of the present invention have various pharmacological effects and thus function to smooth blood circulation inside the pores and to supply nutritional components necessary for hair growth and to promote hair growth by antagonistic effects between components Can be maximized.

Hereinafter, a method for extracting the hair growth promoting component of the present invention will be described with reference to FIG.

FIG. 1 is a sequential view illustrating a process for extracting the hair growth promoting component of the present invention. Referring to FIG. 1, the manufacturing process includes mixing a herbal medicine component and almonds with purified water, heating the mixture to extract a herbal ingredient, cooling the aqueous solution from which the effective ingredient is extracted, and filtering the solid matter.

In the step of mixing the herbal ingredients with the purified water, the ingredient ratio of each ingredient is important. The herbal medicine ingredients are 10-20 parts by weight of green tea, 15-20 parts by weight of gooseberry, 15-20 parts by weight of red ginseng, 10-15 parts by weight of dried jujube, 15-15 parts by weight of guinea pig, 10-15 parts by weight of Angelica gigas, 10-15 parts by weight of mugwort, and 3-5 parts by weight of almond. The purified water is preferably mixed at a weight ratio of 1 to 3 times the mixed herbal medicine material.

According to one embodiment of the present invention, 5 to 10 parts by weight of the plantain may be further mixed and heated in the pressure vessel. Plantain is known to promote the function of the respiratory system, stimulate the secretory nerves, and promote the secretion of mucus from the bronchial tree. It is also known that the tannins contained in plantain glands prevent intracellular lipids from being oxidized and thus have a strong antioxidant effect. The weight ratio of the herbal ingredients is based on the dried herbal ingredients.

It is preferable that a pressure vessel is used in the step of heating the mixture of the raw material, almond and purified water to extract the herbal ingredient. The heating temperature is preferably 110 to 130 ° C. It is possible to shorten the extraction time by progressing the extraction at a temperature higher than the boiling point of water at atmospheric pressure, and the extracted components can be changed into more effective components by high heat . The heating time is preferably 1 to 2 hours.

Natural cooling is preferably used in the step of cooling the aqueous solution from which the active ingredient is extracted and filtering the solids. This is because volatile toxic substances contained in herbal medicine materials can be evaporated and removed through natural cooling. The filtration process is the removal of the solid herbal material contained in the mixture, which can be filtered by applying pressure to the filter net.

The addition of the brown rice enzyme to the hair growth promoting component produced by the above method further improves the hair growth promoting efficiency. The rice husk enzyme is preferably contained in an amount of 0.1 to 1% by weight based on the total weight of the hair growth promoting component prepared by the above method.

The effect of the hair growth promoting component itself of the present invention is also important, but the process of effectively penetrating the pores is also important. Hereinafter, a hair growth promoting method to which the hair growth promoting component of the present invention is applied will be described with reference to FIG.

FIG. 2 is a step-by-step representation of the hair growth promoting method of the present invention. Referring to FIG. 2, the hair growth stimulation method of the present invention comprises the steps of producing a pretreatment liquid, spraying a pretreatment liquid onto a scalp, spraying a hair growth stimulating component onto a scalp, and massaging the scalp.

The step of preparing the pretreatment liquid is a process of widening the inlet of the pores so that the hair growth promoting component can be effectively absorbed into the pores. The process of widening the pores reduces the fatigue of the pores by removing the waste materials inside the pores and functions to open the pores to penetrate the pores effectively. The pretreatment liquid may be prepared by mixing 0.01 to 0.05 parts by weight of red pepper seeds per 100 parts by weight of the solvent in a mixed solvent of distilled water and ethanol at a ratio of 1: 2, stirring the mixture for 4 to 6 hours, and then removing red pepper seeds. Since ethanol is more volatile than water, the concentration of hot pepper seeds is gradually increased by the evaporation of ethanol after the pretreatment liquid is sprayed onto the scalp. In the early stage when the pretreatment liquid comes in contact with the volume, the effect of opening the pores even when the concentration of the red pepper seed ingredient is low occurs, but the concentration of the red pepper seed ingredient increases with time since the scalp can adapt to the red pepper seed material and close the pores again . If the concentration of the red pepper seed component is too high, skin damage may be caused by stimulation to the scalp, and if the concentration of the red pepper seed component is too low, the effect of opening the pore is difficult to occur. Considering these effects, the amount of red pepper seeds is preferably 0.01 to 0.05 parts by weight based on 100 parts by weight of the mixed solvent of water and ethanol, and the stirring time is preferably 4 to 6 hours. Capsicum contains capsaicin, which stimulates the scalp and activates blood circulation in the capillaries of the epidermis, so that waste products can be effectively discharged outside the pores.

The step of spraying the pretreatment liquid onto the scalp is a process for applying the pretreatment liquid evenly to the scalp. A spray device may be used in the spraying process, and it is preferable that the hair is moved while exposing various parts of the scalp while moving the hair. After spraying the pretreatment liquid onto the scalp, leave it for 10 to 20 minutes to induce exhaustion of waste and pore opening. When the time for leaving the pretreatment liquid after spraying becomes too long, it may cause damage to the scalp. After spraying the hair growth promoting composition, the red pepper seed ingredient is diluted so that the scalp is not damaged.

The step of spraying the hair growth stimulating component onto the scalp is a step of infiltrating the components having pharmacological effect into the pores in a state where the pores are widened by the pretreatment liquid. A spray device may be used similarly to the spraying process of the pretreatment liquid, and it is preferable that the spray device is performed while the scalp of various regions is exposed while the hair is being moved. The hair growth promoting component is sprayed on the scalp and left for 30 to 60 minutes. At this time, by adding a massage process of tapping the scalp with a finger tip or the like, penetration effect of the hair restraint composition can be improved. In the massage process, the scalp is stimulated and the blood circulation becomes more active, and the hair pressure promoting ingredient can penetrate into the pores by the physical pressure.

Next, the present invention will be described in more detail with reference to Examples.

Example 1 (Preparation of Pretreatment Liquid)

One liter of distilled water and 2 liters of ethanol were mixed and 0.3 g of ground dried red pepper seeds was added to the above mixed solution in an amount of 100 parts by weight and stirred at room temperature for 5 hours using a mechanical stirrer. Then, dried pulp seeds powder was removed using a filter paper to prepare a pretreatment liquid.

Example 2-1 (Production of hair growth promoting component)

170 g of red ginseng, 170 g of red ginseng, 170 g of dried jujube, 120 g of dried ginseng, 120 g of Angelica keiskei, 120 g of wormwood and 20 g of almond were placed in 2 liters of water and heated in a pressure vessel equipped with a thermometer for 1 hour and 30 minutes. The heating temperature was maintained at 120 캜. Subsequently, the pressure vessel was cooled with the lid of the pressure vessel being opened at room temperature. Subsequently, the solid material and the liquid component were separated using a marginal cloth, and the liquid component was further extracted by squeezing the solid matter using a stick.

Example 2-2 (Preparation of hair growth promoting component)

150 g of green peach, 170 g of red ginseng, 170 g of red ginseng, 170 g of dried jujube, 120 g of dried ginger, 120 g of Angelica gigas, 120 g of wormwood, 20 g of almond and 70 g of plantain were placed in 2 liters of water and heated in a pressure vessel equipped with a thermometer for 1 hour and 30 minutes. The heating temperature was maintained at 120 캜. Subsequently, the pressure vessel was cooled with the lid of the pressure vessel being opened at room temperature. Subsequently, the solid material and the liquid component were separated using a marginal cloth, and the liquid component was further extracted by squeezing the solid matter using a stick.

Example 3-1 (Hair growth stimulation without application of pretreatment liquid)

One female in her 50s and one male in her 30s performed hair stimulation using the hair growth promoting component of Example 2-1. The procedure is as follows.

After shampooing, it was rinsed with hot water and wiped with a towel. Then, the hair growth promoting component of Example 2-1 was sprayed in a spray bottle and sprayed evenly on the scalp. Injection was performed by moving the hair of the recipient and moving the hair around, thereby allowing the composition to escape to all parts of the scalp. Then, the scalp was gently taped using a fingertip for 10 minutes, left to stand for 30 minutes, and shampooed to remove the treatment solutions.

The above procedure was repeated three times a week for one year.

Example 3-2 (Hair growth stimulation treatment using pretreatment liquid)

One female in her twenties, one female in her 50s, and one female in her 60s performed the hair growth stimulation using the pretreatment liquid of Example 1 and the hair growth promoting component of Example 2-1. The procedure was the same as in Example 3-1 except that the pretreatment solution of Example 1 was sprayed onto the scalp before spraying the hair growth promoting component of Example 2-1, sprayed evenly onto the scalp and left for 15 minutes It went on.

Example 3-3 (Hair growth promoting treatment using pretreatment liquid)

One male in her 60s and one female in her 30s performed hair stimulation using the pretreatment liquid of Example 1 and the hair growth promoting component of Example 2-2. The procedure was carried out in the same manner as in Example 3-2 except that the hair growth promoting component of Example 2-2 was used.

Evaluation example (hair growth effect evaluation)

Changes in hair before and after hair growth stimulation were observed in order to evaluate the results of promoting hair growth promoted according to Example 3-1, Example 3-2, and Example 3-3.

Fig. 3 is a photograph evaluating the results of the hair growth promoting procedure according to Example 3-1. Fig. Referring to FIG. 3, a hairless scalp area was widely observed in a 50-year-old woman (upper photograph) before the procedure, but the width of the scalp area without hair was remarkably reduced after the procedure. A male in his thirties (lower image) showed that hair density was very low in the upper area before the procedure, but the density of the hair was increased after the procedure.

4 is a photograph showing evaluation of the results of the hair growth promoting procedure according to Example 3-2. Referring to FIG. 4, in a female in her twenties (upper photograph), partial hair loss occurred in the lower part of the head before the procedure, but partial hair loss area disappeared after the procedure. In the fifties (middle picture), hair density was low in the hair overhead area, but hair density was relatively high after the procedure. A woman in her 60s (lower figure) had partial hair loss in the middle of her head, but the hair loss area disappeared after the procedure.

Fig. 5 is a photograph showing evaluation results of the hair growth promoting procedure according to Example 3-3. Fig. Referring to FIG. 5, a male in his 60's (upper photograph) had severe hair loss before the procedure, but after hair removal, hair loss was stopped and new hair was grown. A woman in their thirties (lower image) showed that the hair became less dense and partly hairless after hair loss on the back of the hair, but after the procedure, new hair grew and the density of hair as a whole increased.

While the present invention has been described in connection with what is presently considered to be practical exemplary embodiments, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, . Therefore, the embodiments described in the present invention are not intended to limit the scope of the present invention but to limit the scope of the present invention. The scope of protection of the present invention should be construed according to the claims, and all technical ideas within the scope of equivalents should be construed as falling within the scope of the present invention.

Claims (5)

(1) As the herbal medicine ingredient, 15 parts by weight of green algae, 17 parts by weight of goose gourd, 17 parts by weight of red ginseng, 17 parts by weight of dried jujube, 12 parts by weight of sulfur, 12 parts by weight of Angelica keiskei, 12 parts by weight of mugwort, 2 parts by weight of purified water and 200 parts by weight of purified water are mixed and the mixture is heated in a pressure vessel at 120 ° C for 1 hour and 30 minutes to extract;
(2) The extracted aqueous solution is spontaneously cooled to room temperature while keeping the cap of the pressure vessel open to obtain an extract in which the volatile components have been removed; And
(3) Extracting solids and liquid components from the extract liquid from which the volatile substances have been removed using a hemp cloth, extracting the liquid components by squeezing solids using a rod, and extracting the hair growth promoting component Way. delete delete delete delete

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