CN115605228A - 一种特异性结合cd137的制剂及其用途 - Google Patents
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (16)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010305482 | 2020-04-17 | ||
CN2020103054827 | 2020-04-17 | ||
PCT/CN2021/087582 WO2021209017A1 (zh) | 2020-04-17 | 2021-04-15 | 一种特异性结合cd137的制剂及其用途 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN115605228A true CN115605228A (zh) | 2023-01-13 |
Family
ID=78084661
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202180028568.2A Pending CN115605228A (zh) | 2020-04-17 | 2021-04-15 | 一种特异性结合cd137的制剂及其用途 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20230285555A1 (zh) |
EP (1) | EP4137155A1 (zh) |
JP (1) | JP2023522024A (zh) |
CN (1) | CN115605228A (zh) |
WO (1) | WO2021209017A1 (zh) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040033228A1 (en) * | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
CN107921104A (zh) * | 2015-02-22 | 2018-04-17 | 索伦托治疗有限公司 | 结合cd137的抗体疗法 |
AU2016249395B2 (en) * | 2015-04-17 | 2022-04-07 | Bristol-Myers Squibb Company | Compositions comprising a combination of an anti-PD-1 antibody and another antibody |
US10875926B2 (en) * | 2015-09-22 | 2020-12-29 | Dingfu Biotarget Co., Ltd. | Fully human antibody against human CD 137 |
BR112019000512A2 (pt) * | 2016-07-14 | 2019-04-24 | Genmab A/S | anticorpo, ácido nucleico, vetor de expressão, célula hospedeira, composição, métodos de tratamento de uma doença, para produzir um anticorpo biespecífico e para detectar se a reticulação entre as células que expressam cd40 e cd137 ocorre em uma amostra, uso de um anticorpo multiespecífico, e, kit |
-
2021
- 2021-04-15 US US17/919,043 patent/US20230285555A1/en active Pending
- 2021-04-15 JP JP2022562634A patent/JP2023522024A/ja active Pending
- 2021-04-15 WO PCT/CN2021/087582 patent/WO2021209017A1/zh unknown
- 2021-04-15 EP EP21788967.4A patent/EP4137155A1/en active Pending
- 2021-04-15 CN CN202180028568.2A patent/CN115605228A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
US20230285555A1 (en) | 2023-09-14 |
WO2021209017A1 (zh) | 2021-10-21 |
EP4137155A1 (en) | 2023-02-22 |
JP2023522024A (ja) | 2023-05-26 |
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Effective date of registration: 20240910 Address after: No. 999, High tech Industrial Park, Baishan City, Jilin Province, China Applicant after: SHIHUIDA PHARMACEUTICALS GROUP (JILIN) Ltd. Country or region after: China Address before: 2nd and 3rd floors, auxiliary building, Wanlong Building, No. 29 Xinfa Road, Suzhou Industrial Park, Suzhou City, Jiangsu Province, China 215127 Applicant before: DINGFU BIOTARGET Co.,Ltd. Country or region before: China |