CN115551545A - SARS-COV-2 mRNA结构域疫苗 - Google Patents

SARS-COV-2 mRNA结构域疫苗 Download PDF

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Publication number
CN115551545A
CN115551545A CN202180013506.4A CN202180013506A CN115551545A CN 115551545 A CN115551545 A CN 115551545A CN 202180013506 A CN202180013506 A CN 202180013506A CN 115551545 A CN115551545 A CN 115551545A
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mrna
seq
amino acid
optionally
nucleotide sequence
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Pending
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Chinese (zh)
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纪尧姆·斯图尔特-琼斯
萨伊达·马哈古卜·埃尔巴希尔
安德烈亚·卡尔菲
米希尔·迈特卡
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ModernaTx Inc
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ModernaTx Inc
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Application filed by ModernaTx Inc filed Critical ModernaTx Inc
Publication of CN115551545A publication Critical patent/CN115551545A/zh
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    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
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    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20071—Demonstrated in vivo effect

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  • Genetics & Genomics (AREA)
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  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202180013506.4A 2020-02-07 2021-02-06 SARS-COV-2 mRNA结构域疫苗 Pending CN115551545A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202062971825P 2020-02-07 2020-02-07
US62/971,825 2020-02-07
US202063016175P 2020-04-27 2020-04-27
US63/016,175 2020-04-27
US202063044330P 2020-06-25 2020-06-25
US63/044,330 2020-06-25
US202063063137P 2020-08-07 2020-08-07
US63/063,137 2020-08-07
PCT/US2021/016979 WO2021159040A2 (en) 2020-02-07 2021-02-06 Sars-cov-2 mrna domain vaccines

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Publication Number Publication Date
CN115551545A true CN115551545A (zh) 2022-12-30

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CN202180013506.4A Pending CN115551545A (zh) 2020-02-07 2021-02-06 SARS-COV-2 mRNA结构域疫苗

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US (1) US20230346914A1 (enExample)
EP (1) EP4100052A2 (enExample)
JP (3) JP7438604B2 (enExample)
KR (1) KR20220140528A (enExample)
CN (1) CN115551545A (enExample)
AU (1) AU2021215938A1 (enExample)
BR (1) BR112022015565A2 (enExample)
CA (1) CA3170150A1 (enExample)
IL (1) IL295377A (enExample)
MX (1) MX2022009707A (enExample)
WO (1) WO2021159040A2 (enExample)

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