CN115551484A - 一种法匹拉韦组合物及其制备方法 - Google Patents
一种法匹拉韦组合物及其制备方法 Download PDFInfo
- Publication number
- CN115551484A CN115551484A CN202080100612.1A CN202080100612A CN115551484A CN 115551484 A CN115551484 A CN 115551484A CN 202080100612 A CN202080100612 A CN 202080100612A CN 115551484 A CN115551484 A CN 115551484A
- Authority
- CN
- China
- Prior art keywords
- composition
- favipiravir
- percent
- weight
- povidone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
一种法匹拉韦组合物、法匹拉韦片剂及其制备方法,组合物包含法匹拉韦或其盐、占组合物重量百分比为2.5%‑15%的崩解剂羧甲基淀粉钠或羧甲基纤维素钙中的一种或两种组合和粘合剂。法匹拉韦组合物药物含量高,可实现法匹拉韦的快速释放,在体外溶出试验中能够在15分钟溶出≥85%。
Description
PCT国内申请,说明书已公开。
Claims (13)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010565808 | 2020-06-19 | ||
CN202010565808X | 2020-06-19 | ||
PCT/CN2020/118723 WO2021253681A1 (zh) | 2020-06-19 | 2020-09-29 | 一种法匹拉韦组合物及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN115551484A true CN115551484A (zh) | 2022-12-30 |
Family
ID=79269111
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202080100612.1A Pending CN115551484A (zh) | 2020-06-19 | 2020-09-29 | 一种法匹拉韦组合物及其制备方法 |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN115551484A (zh) |
WO (1) | WO2021253681A1 (zh) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2011009440A (es) * | 2009-03-13 | 2011-11-04 | Toyama Chemical Co Ltd | Tableta y polvo granulado que contiene 6-fluoro-3-hidroxi-2-pirazi ncarboxamida. |
CN106667926B (zh) * | 2015-11-09 | 2020-01-17 | 石药集团中奇制药技术(石家庄)有限公司 | 一种法匹拉韦片剂及其制备方法 |
CN105687152B (zh) * | 2016-03-22 | 2020-04-07 | 山东齐都药业有限公司 | 一种法匹拉韦快速释放药物制剂及制备方法 |
-
2020
- 2020-09-29 CN CN202080100612.1A patent/CN115551484A/zh active Pending
- 2020-09-29 WO PCT/CN2020/118723 patent/WO2021253681A1/zh active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2021253681A1 (zh) | 2021-12-23 |
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