CN115531247A - Cosmetic preparation with effects of reconstructing sebum membrane and repairing cutin injury - Google Patents
Cosmetic preparation with effects of reconstructing sebum membrane and repairing cutin injury Download PDFInfo
- Publication number
- CN115531247A CN115531247A CN202210451954.9A CN202210451954A CN115531247A CN 115531247 A CN115531247 A CN 115531247A CN 202210451954 A CN202210451954 A CN 202210451954A CN 115531247 A CN115531247 A CN 115531247A
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- China
- Prior art keywords
- parts
- cutin
- skin
- repairing
- cosmetic preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012528 membrane Substances 0.000 title claims abstract description 26
- 210000002374 sebum Anatomy 0.000 title claims abstract description 22
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- 239000002537 cosmetic Substances 0.000 title claims abstract description 18
- 229920000832 Cutin Polymers 0.000 title claims abstract description 15
- 230000006378 damage Effects 0.000 title claims abstract description 11
- 230000000694 effects Effects 0.000 title abstract description 8
- 208000027418 Wounds and injury Diseases 0.000 title description 2
- 208000014674 injury Diseases 0.000 title description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims abstract description 21
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229940032094 squalane Drugs 0.000 claims abstract description 10
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 claims abstract description 8
- 102000008186 Collagen Human genes 0.000 claims abstract description 8
- 108010035532 Collagen Proteins 0.000 claims abstract description 8
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 claims abstract description 8
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 8
- 229940106189 ceramide Drugs 0.000 claims abstract description 8
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 claims abstract description 8
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 8
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 8
- 229920001436 collagen Polymers 0.000 claims abstract description 7
- 150000001413 amino acids Chemical class 0.000 claims abstract description 6
- 230000003902 lesion Effects 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 230000036560 skin regeneration Effects 0.000 claims 1
- 210000003491 skin Anatomy 0.000 abstract description 25
- 230000003020 moisturizing effect Effects 0.000 abstract description 6
- 210000004927 skin cell Anatomy 0.000 abstract description 4
- 229940024606 amino acid Drugs 0.000 abstract description 2
- 229960005188 collagen Drugs 0.000 abstract description 2
- 230000002500 effect on skin Effects 0.000 abstract description 2
- 230000001737 promoting effect Effects 0.000 abstract description 2
- 230000035945 sensitivity Effects 0.000 abstract description 2
- 239000000126 substance Substances 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 4
- 239000010410 layer Substances 0.000 description 4
- 150000002632 lipids Chemical class 0.000 description 4
- 210000000056 organ Anatomy 0.000 description 3
- 206010013786 Dry skin Diseases 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 210000004381 amniotic fluid Anatomy 0.000 description 2
- 210000001188 articular cartilage Anatomy 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 210000000695 crystalline len Anatomy 0.000 description 2
- 210000000805 cytoplasm Anatomy 0.000 description 2
- 210000004207 dermis Anatomy 0.000 description 2
- 230000001050 lubricating effect Effects 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 239000012466 permeate Substances 0.000 description 2
- 210000002826 placenta Anatomy 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 230000008591 skin barrier function Effects 0.000 description 2
- 210000000434 stratum corneum Anatomy 0.000 description 2
- 239000002344 surface layer Substances 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 208000002197 Ehlers-Danlos syndrome Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- -1 dextran aldehyde Chemical class 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical group 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to a cosmetic preparation with the functions of reconstructing a sebum membrane and repairing cutin damage. The preparation contains ceramide, squalane, sodium hyaluronate, amino acid and collagen, can effectively act on a sebum membrane and cutin when being applied to cosmetics, has the effects of moistening and moisturizing, improving the problems of dry and rough skin, promoting the repair effect on skin cells, rebuilding and repairing the sebum membrane and the cutin, effectively improving the skin sensitivity problem and having better popularization prospect.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a cosmetic preparation capable of reconstructing a sebum membrane and repairing cutin damage.
Background
The skin, as the largest organ of the human body, has the functions of preventing the loss of substances such as water, electrolytes and the like in the human body, preventing the invasion of external harmful substances, keeping the stability of the internal environment of the human body and the like, and is a common pursuit target of people for smooth, fine and elastic skin. The skin is mainly composed of a sebum membrane and a horny layer, so that the moisture retention and the resistance of the skin barrier are determined by the soundness of the sebum membrane and the neatness of the arrangement of the horny layer. However, the health of the sebum membrane and the cuticle can be damaged by the problems of over-cleaning, unbalanced skin pH, dry skin and the like, so that the moisture in the skin can run out, and the skin has the problems of dryness, darkness, peeling, blocking powder, allergy, fragility, season-changing redness, dryness, itching and the like. Therefore, the key to improving the symptoms of dry, red, dry and itchy skin is repairing the sebaceous membrane and the stratum corneum. At present, most of products for repairing damaged sebaceous membranes and horny layers on the market have certain irritation to damaged skin barriers, and the effect of repairing damaged sebaceous membranes and horny layers is slow.
Disclosure of Invention
In view of the problems in the prior art, the invention discloses a cosmetic preparation with the functions of reconstructing a skin lipid membrane and repairing cutin damage, which comprises the following main components in parts by weight:
as a preferred embodiment of the present invention, ceramide is a lipid naturally present in the skin, which forms a water-resistant barrier on the skin surface, better protecting the skin, and making it moist and tender. It is similar to the substances that make up the stratum corneum of the skin and helps to renew the natural protective layer of the skin.
As a preferable scheme of the invention, the squalane is hydrocarbon grease obtained by hydrogenating squalene, is lipid closest to sebum of a human body, can be integrated with a sebum membrane to form a protective membrane on the surface layer of skin, and has stable chemical property and difficult oxidation; the squalane has a closed moisturizing effect and can effectively permeate into skin to play roles in moisturizing the skin and repairing skin cells.
As a preferred scheme of the invention, the sodium hyaluronate is an inherent component in a human body, is dextran aldehyde acid, has no species specificity, and is widely present in tissues such as placenta, amniotic fluid, crystalline lens, articular cartilage, skin dermis and the like; it is distributed in cytoplasm and intercellular substance, and has effects of lubricating and nourishing cells and cell organs, and moistening skin.
The invention has the beneficial effects that: the cosmetic preparation capable of reconstructing a sebum membrane and repairing cutin damage, which is provided by the invention, contains ceramide, squalane, sodium hyaluronate, amino acid and collagen, and when the preparation is applied to cosmetics, the preparation can effectively act on the sebum membrane and cutin, has the effects of moistening and moisturizing, and can be used for improving the problems of dry and rough skin, and meanwhile, the preparation can be used for promoting the repairing effect on skin cells, has the effects of reconstructing and repairing the sebum membrane and the cutin, and can be used for effectively improving the skin sensitivity problem, so that the cosmetic preparation has a good popularization prospect.
Detailed Description
Example 1
The invention relates to a cosmetic preparation capable of reconstructing a sebum membrane and repairing cutin damage, which comprises the following main components in parts by weight:
example 2
The invention relates to a cosmetic preparation capable of reconstructing a sebum membrane and repairing cutin damage, which comprises the following main components in parts by weight:
example 3
The invention relates to a cosmetic preparation for reconstructing a sebum membrane and repairing cutin damage, which comprises the following main components in parts by weight:
ceramide can form a waterproof barrier on the skin surface, so that the skin is better protected, and is moistened and tender. Squalane is a lipid closest to sebum of a human body, can be fused with a sebum membrane into a whole, forms a protective membrane on the surface layer of skin, and has stable chemical property and difficult oxidation; the squalane has a closed moisturizing effect and can effectively permeate into skin to play roles in moisturizing the skin and repairing skin cells.
Sodium hyaluronate is an inherent component in human body, and is widely present in tissues such as placenta, amniotic fluid, crystalline lens, articular cartilage, skin dermis and the like; it is distributed in cytoplasm and intercellular substance, and has effects of lubricating and nourishing cells and cell organs, and moistening skin.
Parts not described in detail herein are prior art.
Although the present invention has been described in detail with reference to the specific embodiments, the present invention is not limited to the above embodiments, and various changes and modifications without inventive changes may be made within the knowledge of those skilled in the art without departing from the spirit of the present invention.
Claims (4)
1. A cosmetic preparation with the functions of reconstructing a sebum membrane and repairing cutin damage is characterized by comprising the following main components in parts by weight: 10-20 parts of ceramide, 10-20 parts of squalane, 20-30 parts of sodium hyaluronate, 50-60 parts of amino acid and 40-50 parts of collagen.
2. The cosmetic preparation for the reconstruction of sebum membranes and the repair of keratinous lesions according to claim 1, wherein: the collagen protein gel is composed of 10 parts of ceramide, 10 parts of squalane, 20 parts of sodium hyaluronate, 50 parts of amino acid and 40 parts of collagen.
3. The cosmetic preparation for skin regeneration and cutin damage repair according to claim 1, wherein the cosmetic preparation comprises: the collagen peptide consists of 20 parts of ceramide, 20 parts of squalane, 30 parts of sodium hyaluronate, 60 parts of amino acid and 50 parts of collagen.
4. The cosmetic preparation for the reconstruction of sebum membranes and the repair of keratinous lesions according to claim 1, wherein: the skin care composition is composed of 15 parts of ceramide, 15 parts of squalane, 25 parts of sodium hyaluronate, 55 parts of amino acid and 45 parts of collagen.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210451954.9A CN115531247A (en) | 2022-04-26 | 2022-04-26 | Cosmetic preparation with effects of reconstructing sebum membrane and repairing cutin injury |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210451954.9A CN115531247A (en) | 2022-04-26 | 2022-04-26 | Cosmetic preparation with effects of reconstructing sebum membrane and repairing cutin injury |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115531247A true CN115531247A (en) | 2022-12-30 |
Family
ID=84724228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210451954.9A Pending CN115531247A (en) | 2022-04-26 | 2022-04-26 | Cosmetic preparation with effects of reconstructing sebum membrane and repairing cutin injury |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115531247A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113143792A (en) * | 2021-03-23 | 2021-07-23 | 杭州帝通生物科技有限公司 | Moisturizing repair cream for repairing skin barrier and preparation method thereof |
| CN113827497A (en) * | 2021-10-28 | 2021-12-24 | 苏州九维抗衰科技研究院 | Skin anti-aging formula and preparation method thereof |
-
2022
- 2022-04-26 CN CN202210451954.9A patent/CN115531247A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113143792A (en) * | 2021-03-23 | 2021-07-23 | 杭州帝通生物科技有限公司 | Moisturizing repair cream for repairing skin barrier and preparation method thereof |
| CN113827497A (en) * | 2021-10-28 | 2021-12-24 | 苏州九维抗衰科技研究院 | Skin anti-aging formula and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20221230 |
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| RJ01 | Rejection of invention patent application after publication |