CN1155245A - 胞壁酰肽化合物的应用 - Google Patents
胞壁酰肽化合物的应用 Download PDFInfo
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- CN1155245A CN1155245A CN95194573A CN95194573A CN1155245A CN 1155245 A CN1155245 A CN 1155245A CN 95194573 A CN95194573 A CN 95194573A CN 95194573 A CN95194573 A CN 95194573A CN 1155245 A CN1155245 A CN 1155245A
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- acetyl group
- muramyl
- alanyl
- gmdp
- psoriasis
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- 206010025482 malaise Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 229920001983 poloxamer Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 230000000770 proinflammatory effect Effects 0.000 description 1
- 229940124551 recombinant vaccine Drugs 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 150000004492 retinoid derivatives Chemical class 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- 201000008261 skin carcinoma Diseases 0.000 description 1
- 231100000430 skin reaction Toxicity 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 125000003696 stearoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229940031626 subunit vaccine Drugs 0.000 description 1
- 238000004347 surface barrier Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229940126577 synthetic vaccine Drugs 0.000 description 1
- 235000012976 tarts Nutrition 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- LOIYMIARKYCTBW-UHFFFAOYSA-N trans-urocanic acid Natural products OC(=O)C=CC1=CNC=N1 LOIYMIARKYCTBW-UHFFFAOYSA-N 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
- 125000002987 valine group Chemical group [H]N([H])C([H])(C(*)=O)C([H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 150000003704 vitamin D3 derivatives Chemical class 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9413935A GB9413935D0 (en) | 1994-07-11 | 1994-07-11 | Use of maramyl peptide compounds |
| EP95924437A EP0768888A1 (en) | 1994-07-11 | 1995-07-10 | Use of muramyl peptide compounds |
| SK26-97A SK2697A3 (en) | 1994-07-11 | 1995-07-10 | Use of muramyl peptide compounds and pharmaceutical composition |
| JP8504191A JPH10505580A (ja) | 1994-07-11 | 1995-07-10 | ムラミルペプチド化合物の使用 |
| PCT/GB1995/001619 WO1996001645A1 (en) | 1994-07-11 | 1995-07-10 | Use of muramyl peptide compounds |
| HU9700071A HUT77290A (hu) | 1994-07-11 | 1995-07-10 | Muramilpeptid vegyületek alkalmazása |
| AU28935/95A AU2893595A (en) | 1994-07-11 | 1995-07-10 | Use of muramyl peptide compounds |
| CA002194678A CA2194678A1 (en) | 1994-07-11 | 1995-07-10 | Use of muramyl peptide compounds |
| CZ9747A CZ4797A3 (en) | 1994-07-11 | 1995-07-10 | Use of muramylpeptide compounds and pharmaceutical composition |
| CN95194573A CN1155245A (zh) | 1994-07-11 | 1995-07-10 | 胞壁酰肽化合物的应用 |
| ZA955763A ZA955763B (en) | 1994-07-11 | 1995-07-11 | Use of muramyl peptide compounds |
| IL11454295A IL114542A0 (en) | 1994-07-11 | 1995-07-11 | Use of muramyl peptide compounds |
| BG101126A BG101126A (en) | 1994-07-11 | 1997-01-10 | The use of muramylpeptide compounds |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9413935A GB9413935D0 (en) | 1994-07-11 | 1994-07-11 | Use of maramyl peptide compounds |
| GB9413935.9 | 1994-07-11 | ||
| CN95194573A CN1155245A (zh) | 1994-07-11 | 1995-07-10 | 胞壁酰肽化合物的应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1155245A true CN1155245A (zh) | 1997-07-23 |
Family
ID=25743816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95194573A Pending CN1155245A (zh) | 1994-07-11 | 1995-07-10 | 胞壁酰肽化合物的应用 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0768888A1 (ja) |
| JP (1) | JPH10505580A (ja) |
| CN (1) | CN1155245A (ja) |
| AU (1) | AU2893595A (ja) |
| BG (1) | BG101126A (ja) |
| CA (1) | CA2194678A1 (ja) |
| CZ (1) | CZ4797A3 (ja) |
| GB (1) | GB9413935D0 (ja) |
| HU (1) | HUT77290A (ja) |
| IL (1) | IL114542A0 (ja) |
| SK (1) | SK2697A3 (ja) |
| WO (1) | WO1996001645A1 (ja) |
| ZA (1) | ZA955763B (ja) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108883080A (zh) * | 2015-12-15 | 2018-11-23 | 巴拉特生物技术国际有限公司 | 新颖的胞壁酰肽衍生物化合物、其合成及其用途 |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1038532A4 (en) * | 1997-04-11 | 2003-08-13 | Oleg Vitallievich Kaljuzhin | IMMUNO MODULATOR AND PHARMACEUTICAL COMPOSITIONS WITH ANTITUM PROPERTIES, AND A FOOD ADDITIVE |
| GB9710351D0 (en) * | 1997-05-20 | 1997-07-16 | Scotia Holdings Plc | Glucosamine fatty acids |
| WO1999062537A1 (en) * | 1998-06-04 | 1999-12-09 | The Rockefeller University | Methods and agents for modulating the immune response and inflammation involving monocyte and dendritic cell membrane proteins |
| DE10106852A1 (de) * | 2001-02-14 | 2002-09-05 | T Luger | Entzündungshemmende Verbindungen |
| FR2899466B1 (fr) * | 2006-04-07 | 2008-09-26 | Oreal | Utilisation de compose c-glycoside agent activateur et regulateur de l'immunite cutanee |
| US20120156137A1 (en) | 2006-10-20 | 2012-06-21 | Soo-Youl Kim | Composition for treatment of atopic dermatitis comprising glucosamine and derivatives thereof and a method for treatment of atopic dermatitis using them |
| US8603978B2 (en) * | 2006-12-01 | 2013-12-10 | The United States of America, as represented by the Secretary, Department of Health and Humand Services | Use of muramyl dipeptide (MDP) for treating inflammation |
| FR2933984B1 (fr) * | 2008-07-15 | 2013-01-04 | Univ Bourgogne | D,d muramyldipeptide,composes derives et utilisation pour le traitement des plaques atheromateuses |
| US10610564B2 (en) | 2015-02-26 | 2020-04-07 | Stc.Unm | IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy |
| ES2930246T3 (es) | 2015-12-10 | 2022-12-09 | Bharat Biotech Int Ltd | Nuevo compuesto derivado del péptido muramilo, síntesis y utilizaciones del mismo |
| MX2023011004A (es) | 2021-03-19 | 2024-01-08 | Trained Therapeutix Discovery Inc | Compuestos para regular la inmunidad entrenada y métodos para usarlos. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4357322A (en) * | 1980-07-29 | 1982-11-02 | Syntex (U.S.A.) Inc. | Method of preventing, reducing or inhibiting inflammation |
| US4698330A (en) * | 1983-06-27 | 1987-10-06 | President & Fellows Of Harvard College | Somnogenic compositions and method of use |
| HU205147B (en) * | 1989-06-29 | 1992-03-30 | Sandoz Ag | Process for producing muramyl dipeptide derivative and pharmaceutical compostions comprising same |
| US5506204A (en) * | 1991-11-19 | 1996-04-09 | Peptech (Uk) Limited | Muramyl compounds for treatment of septic shock |
| GB9204354D0 (en) * | 1992-02-28 | 1992-04-08 | Biokine Tech Ltd | Compounds for medicinal use |
| GB9320820D0 (en) * | 1993-10-08 | 1993-12-01 | Biokine Tech Ltd | Compounds for medicinal use |
| GB9326518D0 (en) * | 1993-12-29 | 1994-03-02 | Sandoz Ltd | Organic compounds |
-
1994
- 1994-07-11 GB GB9413935A patent/GB9413935D0/en active Pending
-
1995
- 1995-07-10 AU AU28935/95A patent/AU2893595A/en not_active Abandoned
- 1995-07-10 EP EP95924437A patent/EP0768888A1/en not_active Withdrawn
- 1995-07-10 HU HU9700071A patent/HUT77290A/hu unknown
- 1995-07-10 JP JP8504191A patent/JPH10505580A/ja active Pending
- 1995-07-10 CZ CZ9747A patent/CZ4797A3/cs unknown
- 1995-07-10 CN CN95194573A patent/CN1155245A/zh active Pending
- 1995-07-10 WO PCT/GB1995/001619 patent/WO1996001645A1/en not_active Application Discontinuation
- 1995-07-10 CA CA002194678A patent/CA2194678A1/en not_active Abandoned
- 1995-07-10 SK SK26-97A patent/SK2697A3/sk unknown
- 1995-07-11 IL IL11454295A patent/IL114542A0/xx unknown
- 1995-07-11 ZA ZA955763A patent/ZA955763B/xx unknown
-
1997
- 1997-01-10 BG BG101126A patent/BG101126A/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108883080A (zh) * | 2015-12-15 | 2018-11-23 | 巴拉特生物技术国际有限公司 | 新颖的胞壁酰肽衍生物化合物、其合成及其用途 |
| CN108883080B (zh) * | 2015-12-15 | 2021-12-21 | 巴拉特生物技术国际有限公司 | 胞壁酰肽衍生物化合物、其合成及其用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| GB9413935D0 (en) | 1994-08-31 |
| AU2893595A (en) | 1996-02-09 |
| HUT77290A (hu) | 1998-03-30 |
| JPH10505580A (ja) | 1998-06-02 |
| IL114542A0 (en) | 1995-11-27 |
| CZ4797A3 (en) | 1997-07-16 |
| CA2194678A1 (en) | 1996-01-25 |
| EP0768888A1 (en) | 1997-04-23 |
| ZA955763B (en) | 1997-01-13 |
| HU9700071D0 (en) | 1997-02-28 |
| BG101126A (en) | 1997-09-30 |
| SK2697A3 (en) | 1997-08-06 |
| WO1996001645A1 (en) | 1996-01-25 |
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| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |