CN115487262A - Composition for improving cardiovascular and cerebrovascular diseases and hypertension and preparation method thereof - Google Patents

Composition for improving cardiovascular and cerebrovascular diseases and hypertension and preparation method thereof Download PDF

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CN115487262A
CN115487262A CN202211340750.4A CN202211340750A CN115487262A CN 115487262 A CN115487262 A CN 115487262A CN 202211340750 A CN202211340750 A CN 202211340750A CN 115487262 A CN115487262 A CN 115487262A
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composition
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cerebrovascular diseases
hypertension
improving cardiovascular
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杨贝林
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Abstract

The invention provides a composition for improving cardiovascular and cerebrovascular diseases and hypertension and a preparation method thereof, and relates to the technical field of health care products. A composition for improving cardiovascular and cerebrovascular diseases and hypertension comprises the following components in parts by weight: 10-30 parts of astragalus membranaceus, 1-15 parts of aloe, 5-20 parts of pseudo-ginseng flowers, 1-15 parts of pseudo-ginseng and 10-25 parts of chrysanthemum. The preparation method comprises the following steps: cleaning raw materials, drying, pulverizing, adding water into the pulverized powder, stirring, making into watered pill, and oven drying. The composition can achieve the purpose of improving cardiovascular and cerebrovascular diseases and hypertension by expanding blood vessels, activating blood circulation to dissipate blood stasis and reducing blood viscosity, is simple and convenient to prepare, and is beneficial to enhancing the medicinal effect of the composition.

Description

Composition for improving cardiovascular and cerebrovascular diseases and hypertension and preparation method thereof
Technical Field
The invention relates to the technical field of health care products, in particular to a composition for improving cardiovascular and cerebrovascular diseases and hypertension and a preparation method thereof.
Background
The main reason for cardiovascular and cerebrovascular diseases is that the abnormal metabolism of smooth muscle cells in the vascular wall is caused, the metabolism of vascular tissues and other tissues of a human body is completed in a certain period, but as new cellular tissues cannot be normally formed, the vascular wall has defects, so that the constriction of inflammatory blood vessels is easy to generate, and the possibility of blockage or rupture exists at any time. Furthermore, due to long-term eating habits, the food is rich in lipid and alcohol. Meanwhile, reasonable movement does not promote the metabolism of lipid alcohols, so that lipid alcohols in the body are gradually increased; in addition, with the increase of age, the capability of human body to secrete antioxidant enzyme (such as superoxide dismutase SOD) is reduced, so that the level of free radicals in the body is increased, low-density lipoprotein cholesterol in blood fat is oxidized and deposited on the blood vessel wall, the blood vessel is blocked for a long time, and lipid and alcohol substances are easy to combine with free mineral ions in the body to form thrombus and generate cardiovascular and cerebrovascular diseases.
Hypertension (hypertension) is a clinical syndrome characterized by an increase in systemic arterial blood pressure (systolic pressure and/or diastolic pressure) (systolic pressure not less than 140 mm hg, diastolic pressure not less than 90 mm hg), which may be accompanied by functional or organic damage to organs such as heart, brain, kidney, etc.
At present, no specific medicine is available for treating cardiovascular and cerebrovascular diseases and hypertension, but medicines of chemical preparations are generally used in the process of treating cardiovascular and cerebrovascular diseases or hypertension, the side effects of the medicines are large, the medicines can greatly damage other organs of a user in the process of reducing blood pressure, and the disease condition can be repeated in a short time after stopping the medicine.
Disclosure of Invention
The invention aims to provide a composition for improving cardiovascular and cerebrovascular diseases and hypertension, which can achieve the purpose of improving the cardiovascular and cerebrovascular diseases and hypertension by expanding blood vessels, activating blood circulation to dissipate blood stasis and reducing blood viscosity, and can effectively avoid side effects and ensure that the composition is safer and healthier to use by utilizing medicinal and edible medicinal materials.
The invention also aims to provide a preparation method of the composition for improving cardiovascular and cerebrovascular diseases and hypertension, which is simple and convenient and is beneficial to enhancing the medicinal effect of the composition.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
The invention provides a composition for improving cardiovascular and cerebrovascular diseases and hypertension, which comprises the following raw materials in parts by weight: 10-30 parts of astragalus membranaceus, 1-15 parts of aloe, 5-20 parts of pseudo-ginseng flower, 1-15 parts of pseudo-ginseng and 10-25 parts of chrysanthemum.
The invention provides a preparation method of a composition for improving cardiovascular and cerebrovascular diseases and hypertension, which comprises the following steps:
cleaning raw materials, drying, pulverizing, adding water into the pulverized powder, stirring, making into watered pill, and oven drying.
The embodiment of the invention at least has the following beneficial effects:
according to the invention, astragalus membranaceus can play a role in reducing blood pressure by expanding blood vessels, inhibit the secretion of angiotensin converting enzyme of endothelial cells and enhance the expression of ACE2 and mRNA thereof by virtue of calycosin contained in astragalus membranaceus, so that the signal paths of vascular endothelial cell growth factors and fibroblast growth factors are regulated to realize angiogenesis, humoral immunity and cellular immunity can be promoted to improve the immune function of an organism, and further cardiovascular and cerebrovascular diseases are prevented or improved. The aloe-containing calcium isocitrate can dilate capillary vessels to achieve the effect of lowering blood pressure, can also enhance the disease resistance of human bodies, and regulate lipid metabolism of the organisms to achieve the effect of assisting in lowering blood pressure. The notoginseng flower can quickly expand blood vessels to smooth blood flow, soften the blood vessels, reduce the viscosity of the blood, clear the calcium deposition on the blood vessel wall, activate vascular endothelin, reduce the hematocrit, prolong the prothrombin time, reduce the quantity of fibrin, effectively prevent platelet aggregation and prevent the increase of the blood viscosity, thereby playing the roles of regulating blood fat and preventing thrombus. The notoginseng can delay the decomposition of high-energy phosphate compounds in cells during ischemia, improve the brain energy exhaustion caused by ischemia, has obvious brain protection effect, can expand coronary artery, promote the formation of collateral circulation of experimental myocardial infarction area, increase the blood flow of the coronary artery, improve myocardial blood oxygen supply, increase the content of platelet inner cyclic adenosine monophosphate (cAMP), reduce the generation of thromboxane A2, inhibit platelet aggregation and reduce the viscosity of plasma. The flavonoids contained in flos Chrysanthemi have effects of reducing blood lipid, reducing cholesterol, inhibiting thrombosis and dilating coronary artery, and can be used for treating hypertension and arteriosclerosis; rutin, luteolin-7-glucoside, robinin, kaempferol, quercetin, baicalein, apigenin, etc. in flos Chrysanthemi have different curative effects on cardiovascular disease and cerebrovascular disease. The combination of the above medicines can play a role in regulating blood pressure, expanding blood vessels, reducing blood viscosity, inhibiting platelet aggregation, enhancing immunity and the like so as to achieve the purpose of treating hypertension and cardiovascular and cerebrovascular diseases, and the medicines are reasonable in compatibility and supplement each other in efficacy. And medicinal and edible medicinal materials are utilized, so that side effects can be effectively avoided, the injury to organs is prevented, and the composition is safer and healthier to use.
In the invention, the raw materials are crushed and added with water to prepare the water-bindered pills, so that the loss of active ingredients of the raw materials can be reduced, the drug effect of the composition is improved, and the composition is convenient to take and carry and has higher convenience.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are conventional products which are not indicated by manufacturers and are commercially available.
It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
A composition for improving cardiovascular and cerebrovascular diseases and hypertension comprises the following raw materials in parts by weight: 10-30 parts of astragalus membranaceus, 1-15 parts of aloe, 5-20 parts of pseudo-ginseng flowers, 1-15 parts of pseudo-ginseng and 10-25 parts of chrysanthemum.
Astragalus root, radix astragali, mild in nature and sweet in taste, enters spleen and lung meridians, has the effects of invigorating qi and raising yang, consolidating superficial resistance and arresting sweating, inducing diuresis and relieving swelling, promoting the production of body fluid and nourishing blood, activating stagnancy and relieving arthralgia, expelling toxin and pus, healing sore and promoting granulation. The astragalus has the effect and function of promoting the metabolism of nucleic acid; enhancing hematopoietic function; improving myocardial function, and resisting myocardial infarction; has antioxidant, antiviral, anticancer, renal function improving, and renal histopathological changes improving effects. The decoction has effects of regulating immunity, resisting aging and stress. The astragalus contains saponin, flavone, polysaccharide, amino acid, linoleic acid, alkaloid, choline and the like, and the compounds have stronger biological activity. Astragalus root can enhance the phagocytic function of reticuloendothelial system, increase the number of white blood cells and multinucleate cells, increase the phagocytic percentage and phagocytic index of phagocytic cells, and promote humoral immunity and cellular immunity. The astragalus polysaccharide and the astragalus saponin can protect myocardial cells, reverse myocardial hypertrophy to a certain extent, prevent heart failure, reduce the activities of phosphocreatine kinase and lactate dehydrogenase of patients with myocardial ischemia and reduce the area of myocardial infarction. The astragalus has a certain bidirectional regulating effect on blood pressure, can dilate blood vessels, mildly and durably reduce the blood pressure, and can increase and keep the blood pressure of shock animals stable. In addition, astragalus has a protective effect on vascular endothelial cells, the mechanism of the astragalus is that calycosin contained in astragalus can inhibit the secretion of angiotensin converting enzyme of endothelial cells and enhance the expression of ACE2 and mRNA thereof, and the calycosin can also regulate the signal paths of vascular endothelial cell growth factors and fibroblast growth factors, so that angiogenesis is realized.
Aloe, cold in nature, bitter in taste, enter large intestine meridian, stomach meridian, liver meridian, clear liver heat, relax bowels, kill parasite and cure malnutrition, have diarrhea causing, antibacterial, anti-tumor effects, can lengthen the life cycle of sarcoma mouse; has liver protecting and stomach injury resisting effects, and can be used for treating diarrhea caused by intestinal cavity water increase; has effects in treating tissue injury and protecting skin; can stimulate the growth of fibroblasts; affecting the function of the immune system, etc.; can promote wound healing, relieve inflammation, and enhance immunity. The calcium isocitrate in aloe can dilate capillary vessels to reduce blood pressure. Aloe can enhance disease resistance of human body, has effects of invigorating stomach and catharsis, and is beneficial for repairing gastrointestinal mucosa, regulating organism lipid metabolism, and reducing body fat to assist in lowering blood pressure.
Notoginseng flower, sweet and cool, enters liver channel and heart channel, and has the effects of clearing heat, calming liver and lowering blood pressure. The notoginseng flower can obviously reduce the MDA content in the liver, inhibit peroxidation and reduce the damage of MDA to the human body. Meanwhile, the content of the GSH is increased, so that enough GSH can resist peroxidation, and the Notoginseng flower has the effects of scavenging free radicals and inhibiting lipid peroxidation. The saponin in Notoginseng can rapidly expand blood vessel, dredge blood flow, soften blood vessel, resist thrombi, reduce blood viscosity, remove calcium deposition on blood vessel wall, activate vascular endothelin, and regulate blood lipid abnormality. The panax notoginseng flower saponins can obviously reduce the whole blood viscosity of a blood stasis rat, reduce the hematocrit of the blood stasis rat, prolong the prothrombin time, reduce the quantity of fibrin, effectively prevent platelet aggregation and prevent the blood viscosity from increasing, thereby playing a role in preventing thrombus. In addition, the notoginseng flowers can play a role in reducing blood pressure by regulating the systolic pressure and the diastolic pressure of SHR. Notoginseng saponin of Notoginseng has effects of regulating arrhythmia caused by coronary atherosclerosis, enhancing myocardium oxygen supply capability of patient, increasing coronary blood flow, and protecting heart. Ginsenoside Rb2 in Notoginseng radix has effects of stabilizing central nerve, slowing heart rate and lowering blood pressure in rat, improving nerve function defect, reducing intracerebral infarction area, relieving encephaledema, and protecting cerebral ischemia injury by resisting oxidation injury.
Notoginseng, radix Notoginseng, with warm nature, sweet and slightly bitter taste, enters liver and stomach meridians, and has effects of dispelling blood stasis, stopping bleeding, and relieving swelling and pain. Notoginseng radix has hemostatic, platelet aggregation inhibiting, thrombolytic, hemolytic, and hematopoietic effects; has effects in resisting arrhythmia, atherosclerosis, anoxia, shock, and cerebral ischemia for cardiovascular system; has effects of inhibiting central nerve and relieving pain; it has effects in enhancing immunity, protecting liver function, resisting tumor, delaying aging, lowering blood sugar, relieving inflammation, regulating metabolism, and promoting growth; has low toxicity and basically no side effect after long-term administration. The panax notoginseng saponins can delay the decomposition of high-energy phosphate compounds in cells during ischemia, improve the brain energy exhaustion caused by ischemia and have obvious brain protection effect; notoginseng radix has effects of dilating coronary artery, promoting collateral circulation of experimental myocardial infarction area, increasing coronary blood flow, and improving myocardial blood oxygen supply. Can inhibit myocardial contractility, slow down heart rate, reduce peripheral vascular resistance, reduce oxygen consumption of myocardium, directly inhibit myocardium, and effectively treat arrhythmia induced by various medicines. The Panax notoginsenosides can increase the content of platelet internal cyclic adenosine monophosphate (cAMP), reduce the generation of thromboxane A2, inhibit platelet aggregation, and reduce the viscosity of plasma.
The chrysanthemum is slightly cold in nature, sweet and bitter in taste, enters lung and liver meridians, dissipates wind, clears heat, calms liver and improves eyesight, and has the effects of resisting bacteria, expanding coronary artery, increasing coronary flow, improving myocardial oxygen consumption and the like. The flavonoids contained in flos Chrysanthemi have effects of reducing blood lipid, reducing cholesterol, inhibiting thrombosis and dilating coronary artery, and can be used for treating hypertension and arteriosclerosis; rutin, luteolin-7-glucoside, robinin, kaempferol, quercetin, baicalein, apigenin, etc. in flos Chrysanthemi have different curative effects on cardiovascular disease and cerebrovascular disease.
In the embodiment, the composition for improving cardiovascular and cerebrovascular diseases and hypertension also comprises 1-10 parts by weight of selfheal and 2-8 parts by weight of dendrobium.
Spica Prunellae is cold in nature, pungent and bitter in taste, belongs to liver and gallbladder meridians, has effects of clearing pathogenic fire, improving eyesight, resolving hard mass, and relieving swelling, and has effects of lowering blood pressure, resisting arrhythmia, resisting inflammation, suppressing immunity, reducing blood sugar, resisting bacteria, resisting virus, and resisting cell toxicity.
The dendrobium nobile is slightly cold in nature and sweet in taste, enters the stomach channel and the kidney channel, has the effects of tonifying stomach, promoting the production of body fluid, nourishing yin and clearing heat, has the effect of regulating smooth muscle, has the effect of inhibiting the heart, can reduce myocardial contractility, reduces blood pressure and can enhance the immune function of the organism. Herba Dendrobii can significantly improve superoxide dismutase Hua Mei (SOD) level, reduce Lipid Peroxide (LPO), regulate brain monoamine neuromediator level, inhibit monoamine oxidase (MAO), and delay aging, and herba Dendrobii polysaccharide also has effects of significantly enhancing immunity, resisting aging, and resisting radiation. The herba Dendrobii contains ester components, and has effects of promoting blood circulation for removing blood stasis, dilating blood vessel, resisting platelet coagulation, improving cardiovascular and cerebrovascular function, and treating thromboangiitis obliterans, cerebral thrombosis, arteriosclerosis obliterans, etc.
In the embodiment, the composition for improving cardiovascular and cerebrovascular diseases and hypertension further comprises 2-7 parts by weight of cassia twig.
Cassia twig, pungent and sweet in flavor and warm in nature, enters bladder channel, heart channel and lung channel, releases superficies to relieve muscles, warms channels and promote blood circulation, supports yang to regulate qi, levels and lowers qi, and has certain antibacterial and antiviral effects; has antipyretic, analgesic, tranquilizing, and anticonvulsive effects on central system; has obvious anti-inflammatory effect; can increase myocardial nutritional blood flow, and has antiallergic and anticoagulant effects. The cassia twig contains a large amount of cassia twig oil substances, can accelerate the blood circulation of a human body, reduce the blood viscosity, and has the effects of reducing blood pressure and preventing and treating hypertension.
A preparation method of a composition for improving cardiovascular and cerebrovascular diseases and hypertension comprises the following steps:
cleaning raw materials, drying at 70-90 deg.C for 20-40min, micronizing into powder with particle size of 180-220 meshes, adding water into the powder, and mixing the powder and water at a mass ratio of 10: (1-4), stirring, making into watered pill, and spray drying at 50-60 deg.C until water content is less than 5%.
Adding water into the pulverized powder, and adding ganoderma lucidum spore oil, perilla seed oil and soybean oil before stirring, wherein the mass ratio of the ganoderma lucidum spore oil to the perilla seed oil to the soybean oil is 5:3:2.
the delicacies compound contained in the ganoderma lucidum spore oil has good biological activity, can effectively inhibit the release of in vivo cell histidinamine, can also play a role in reducing the activity of angiotensin enzyme, is beneficial to reducing blood pressure, can also play a role in regulating the liver function of a human body, and has the effects of reducing blood fat and reducing blood pressure. The Ganoderma spore oil also contains Ganoderma polysaccharide, triterpenes ganoderic acid, unsaturated fatty acid and various nutrients, and can supplement nutrients required by human body and improve immunity. The ganoderma spore oil can purify blood, soften blood vessel, and assist antivirus. The Ganoderma spore oil can accelerate metabolism of human body, promote discharge of toxic substances in vivo, and avoid angiosclerosis.
Perilla seed oil has effects of inhibiting platelet aggregation, resisting atherosclerosis, and preventing cerebral thrombosis. The perilla seed oil contains alpha-linolenic acid, can reduce blood pressure, can generate EPA and DHA after being metabolized in a human body, and can prevent cardiovascular and cerebrovascular diseases. The soybean oil is rich in vitamin E and unsaturated fatty acid essential to human body, and has effects of reducing blood lipid, lowering blood pressure, and softening blood vessel.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
A preparation method of a composition for improving cardiovascular and cerebrovascular diseases and hypertension comprises the following steps:
raw materials: 10g of astragalus, 1g of aloe, 5g of pseudo-ginseng flower, 1g of pseudo-ginseng and 10g of chrysanthemum;
cleaning raw materials, drying at 70 deg.C for 20min, micronizing into powder with particle size of 180 mesh, adding water into the powder, and mixing the powder and water at a mass ratio of 10:3, stirring, preparing into water pills, and spray drying at 50 ℃ until the water content is lower than 5%.
Example 2
A preparation method of a composition for improving cardiovascular and cerebrovascular diseases and hypertension comprises the following steps:
raw materials: 15g of astragalus, 5g of aloe, 8g of pseudo-ginseng flower, 10g of pseudo-ginseng and 15g of chrysanthemum;
cleaning raw materials, drying at 80 deg.C for 30min, micronizing into powder with particle size of 200 mesh, adding water into the powder, wherein the mass ratio of powder to water is 10:4, stirring, preparing into water pills, and spray drying at 60 ℃ until the water content is lower than 5%.
Example 3
A preparation method of a composition for improving cardiovascular and cerebrovascular diseases and hypertension comprises the following steps:
raw materials: 20 g of astragalus membranaceus, 10g of aloe, 15g of pseudo-ginseng flower, 10g of pseudo-ginseng, 15g of chrysanthemum, 5g of selfheal and 5g of dendrobium;
cleaning raw materials, drying at 80 deg.C for 40min, micronizing into 220 mesh powder, adding water into the powder, wherein the mass ratio of powder to water is 10:4, stirring, preparing into water pills, and spray drying at 60 ℃ until the water content is lower than 5%.
Example 4
A preparation method of a composition for improving cardiovascular and cerebrovascular diseases and hypertension comprises the following steps:
raw materials: 15g of astragalus membranaceus, 5g of aloe, 15g of pseudo-ginseng flower, 15g of pseudo-ginseng, 15g of chrysanthemum, 5g of selfheal, 5g of dendrobe and 5g of cassia twig;
cleaning raw materials, drying at 90 deg.C for 30min, micronizing into powder with particle size of 180 mesh, adding water into the powder, and mixing the powder and water at a mass ratio of 10:4, stirring, preparing into water pills, and spray drying at 60 ℃ until the water content is lower than 5%.
Example 5
A preparation method of a composition for improving cardiovascular and cerebrovascular diseases and hypertension comprises the following steps:
raw materials: 15g of astragalus, 10g of aloe, 10g of pseudo-ginseng flower, 10g of pseudo-ginseng and 15g of chrysanthemum;
cleaning raw materials, drying at 80 deg.C for 30min, micronizing into powder with particle size of 200 mesh, adding water into the powder, wherein the mass ratio of powder to water is 10:1, adding 4mL of ganoderma spore oil, 2.4mL of perilla oil and 1.6mL of soybean oil, stirring, making into watered pill, and spray drying at 60 deg.C until the water content is less than 5%.
Test results
5 hypertensive volunteers were selected and administered the compositions prepared in examples 1-5 of the present invention, 10g each time, in the morning and evening daily for 3 months, and blood pressure was recorded as follows:
TABLE 1 blood pressure changes
Figure BDA0003916134500000101
Figure BDA0003916134500000111
As can be seen from Table 1, the volunteers of examples 1-5 had significantly reduced systolic and diastolic blood pressure. The composition prepared by the invention can treat hypertension and has a good effect.
In addition, 5 volunteers with cardiovascular and cerebrovascular diseases with symptoms of: palpitation, shortness of breath, paroxysmal dyspnea at night, dizziness, fullness in the head, chest pain. The composition of examples 1-5 of the present invention was administered to 5 volunteers, 10g each in the morning and evening daily, for 1 month, and the symptoms of the volunteers were recorded as follows:
TABLE 2 symptom Change
Figure BDA0003916134500000112
As can be seen from Table 2, the compositions of examples 1 to 5 exhibited significant improvement in palpitation, shortness of breath, night paroxysmal dyspnea, dizziness, fullness in the head, and chest pain. The composition prepared by the invention can be used for treating cardiovascular and cerebrovascular diseases.
In conclusion, the composition for improving cardiovascular and cerebrovascular diseases and hypertension provided by the embodiment of the invention has the advantages that the raw materials are matched, the effects of regulating blood pressure, expanding blood vessels, reducing blood viscosity, inhibiting platelet aggregation, enhancing immunity and the like can be realized, the purpose of treating hypertension and cardiovascular and cerebrovascular diseases is realized, the compatibility is reasonable, and the effects supplement each other. And medicinal and edible medicinal materials are utilized, so that side effects can be effectively avoided, the injury to organs is prevented, and the composition is safer and healthier to use.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Claims (10)

1. The composition for improving cardiovascular and cerebrovascular diseases and hypertension is characterized by comprising the following raw materials in parts by weight: 10-30 parts of astragalus membranaceus, 1-15 parts of aloe, 5-20 parts of pseudo-ginseng flowers, 1-15 parts of pseudo-ginseng and 10-25 parts of chrysanthemum.
2. The composition for improving cardiovascular and cerebrovascular diseases and hypertension according to claim 1, further comprising 1-10 parts by weight of selfheal and 2-8 parts by weight of dendrobium.
3. The composition for improving cardiovascular and cerebrovascular diseases and hypertension according to claim 2, further comprising 2 to 7 parts by weight of cinnamon twig.
4. A method for preparing the composition for improving cardiovascular and cerebrovascular diseases and hypertension according to any one of claims 1 to 3, which comprises the following steps:
cleaning raw materials, drying, pulverizing, adding water into the pulverized powder, stirring, making into watered pill, and oven drying.
5. The method for preparing a composition for improving cardiovascular and cerebrovascular diseases and hypertension according to claim 4, wherein the drying is performed at 70-90 ℃ for 20-40min.
6. The method for preparing a composition for improving cardiovascular and cerebrovascular diseases and hypertension according to claim 4, wherein the composition is prepared by micronizing to obtain powder with particle size of 180-220 mesh.
7. The preparation method of the composition for improving cardiovascular and cerebrovascular diseases and hypertension according to claim 4, wherein the mass ratio of the powder to the water is 10: (1-4).
8. The method for preparing a composition for improving cardiovascular and cerebrovascular diseases and hypertension according to claim 4, wherein the composition is spray-dried at 50-60 ℃ until the water content is less than 5%.
9. The method for preparing a composition for improving cardiovascular and cerebrovascular diseases and hypertension according to claim 4, wherein the step of adding water to the pulverized powder further comprises adding Ganoderma lucidum spore oil, perilla frutescens seed oil and soybean oil before stirring.
10. The method for preparing a composition for improving cardiovascular and cerebrovascular diseases and hypertension according to claim 9, wherein the mass ratio of ganoderma lucidum spore oil, perilla oil and soybean oil is 5:3:2.
CN202211340750.4A 2022-10-29 2022-10-29 Composition for improving cardiovascular and cerebrovascular diseases and hypertension and preparation method thereof Withdrawn CN115487262A (en)

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