CN115486542A - Composite probiotic powder beneficial to lipid-lowering metabolism and preparation method thereof - Google Patents

Composite probiotic powder beneficial to lipid-lowering metabolism and preparation method thereof Download PDF

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CN115486542A
CN115486542A CN202211117988.0A CN202211117988A CN115486542A CN 115486542 A CN115486542 A CN 115486542A CN 202211117988 A CN202211117988 A CN 202211117988A CN 115486542 A CN115486542 A CN 115486542A
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parts
powder
probiotic powder
lipid
lowering
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涂醉桃
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Shanghai Junxiaobao Health Technology Co ltd
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Shanghai Junxiaobao Health Technology Co ltd
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Abstract

The invention discloses composite probiotic powder beneficial to lipid-lowering metabolism and a preparation method thereof, wherein the composite probiotic powder beneficial to lipid-lowering metabolism comprises the following raw materials in parts by weight: 190-98 parts of probiotic powder, 21-5 parts of probiotic powder, 0.01-2 parts of bifidobacterium lactis B420, 0.01-2 parts of bifidobacterium lactis HN0190.01-2 parts of bifidobacterium breve B-30.01-2 parts of lactobacillus acidophilus NCFM0.01-2 parts of lactobacillus rhamnosus 65940.01-2 parts, 299v0.01-2 parts of lactobacillus plantarum, 0.01-2 parts of potato extract, 0.01-2 parts of flammulina velutipes powder and 0.01-2 parts of white kidney bean extract. The invention has reasonable design, has good lipid-lowering and metabolism-improving effects by the cooperation of a plurality of probiotics, has obvious weight-losing effect, is suitable for wide crowds, can control oxygen and water indexes in the product, and effectively prevents external stimulation such as light, heat and the like, thereby better preserving the activity of the probiotics and ensuring the quality of the product in the shelf life.

Description

Composite probiotic powder beneficial to lipid-lowering metabolism and preparation method thereof
Technical Field
The invention relates to the technical field of probiotic preparations, in particular to composite probiotic powder beneficial to lipid-lowering metabolism and a preparation method thereof.
Background
For the intervention and treatment of obesity, the current lifestyle intervention combining the exercise therapy and the diet therapy is more effective and most advocated, but the efficiency is low, the period is long, and the patient is difficult to persist. Surgical intervention is also one of the effective weight loss methods, but is often high in risk and expensive, and is difficult for patients to bear; in addition, the medicine has high treatment efficiency, good effect, low risk and easy acceptance by patients, but part of the medicines can cause serious adverse reactions to the patients. Therefore, development of new natural ingredients for body fat reduction is urgently required.
At present, a large number of researches show that obesity is closely related to intestinal flora, and probiotics can reduce the serum total cholesterol and triglyceride levels of obesity model mice induced by high-fat diet, improve lipid metabolism, reduce fat accumulation in vivo and reduce body weight, thereby reducing the risk of obesity-related diseases. Some probiotic products mainly aiming at slimming are available in the market, but the disadvantages of low bacterial activity, mixed components and the like generally exist, and the quality of the products in the shelf life cannot be guaranteed, so that the composite probiotic powder which is helpful for reducing blood fat metabolism and the preparation method thereof are provided.
Disclosure of Invention
The invention aims to solve the problems in the prior art, and provides the composite probiotic powder beneficial to lipid-lowering metabolism and the preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
the composite probiotic powder helpful for lipid-lowering metabolism comprises the following raw materials in parts by weight: 190-98 parts of probiotic powder, 21-5 parts of probiotic powder, 0.01-2 parts of bifidobacterium lactis B420, 0.01-2 parts of bifidobacterium lactis HN0190.01-2 parts of bifidobacterium breve B-30.01-2 parts of lactobacillus acidophilus NCFM0.01-2 parts of lactobacillus rhamnosus 65940.01-2 parts, 0.01-2 parts of lactobacillus plantarum 299v, 0.01-2 parts of potato extract, 0.01-2 parts of flammulina velutipes powder and 0.01-2 parts of white kidney bean extract.
Preferably, the probiotic powder 1 comprises the following raw materials in parts by weight: 40-44 parts of resistant dextrin, 4-8 parts of xylo-oligosaccharide, 2-6 parts of erythritol, 34-38 parts of cranberry fruit powder, 130.3-0.7 part of lactobacillus plantarum N, 0.01-0.05 part of lactobacillus rhamnosus LRa050, 0.2-0.6 part of pediococcus acidilactici CCFM79020, 0.04-0.08 part of bifidobacterium lactis Bla, 26-30 parts of fructo-oligosaccharide and 20-24 parts of stachyose.
Preferably, the probiotic powder 2 comprises the following raw materials in parts by weight: bifidobacterium animalis CP-90.01-0.05 parts, fructo-oligosaccharide 12-16 parts, and Lactobacillus rhamnosus bv-77.04-0.08 parts.
Preferably, the number of the viable bacteria of each strain is 2-6 multiplied by 10 10 CFU/g。
A method for preparing a composite probiotic powder for aiding lipid-lowering metabolism, the method comprising the steps of:
s1, adding distilled water into a stirring kettle, adding probiotic powder 1, probiotic powder 2, bifidobacterium lactis B420, bifidobacterium lactis HN019, bifidobacterium breve B-3, lactobacillus acidophilus NCFM, lactobacillus rhamnosus 6594, lactobacillus plantarum 299v, a potato extract, flammulina velutipes powder and a white kidney bean extract into the stirring kettle one by one, stirring clockwise in the adding process at the rotation speed of 100-120r/min, continuing stirring for 26-30min after the adding is finished at the rotation speed of 160-180r/min to obtain a first mixed raw material;
s2, adjusting the temperature of a freeze drying oven to 0-4 ℃, adding the first mixed raw material into the drying oven for freeze drying, wherein the freeze drying temperature is-40 ℃ to-36 ℃, the pressure of the freeze drying oven is 1-9Pa, and the freeze drying time is 18-22h;
s3, putting the freeze-dried mixed raw material I into a granulator, and extruding and granulating the mixed raw material I until the particle size is 20-40 meshes to obtain a powder raw material I;
s4, grinding the powder raw material I for 2-4h by using a ball mill, and screening by using a vibration screening machine after grinding is finished to obtain a powder raw material II with the particle size of 160-200 meshes;
s5, treating the powder raw material II through a triple embedding technology to obtain powder particles;
s6, packaging the powder particles into a packaging shell through a packaging machine, vacuumizing and filling nitrogen into the packaging shell, and controlling the water content of the product to be 3% -7% and the oxygen content to be 1% -1.8% to obtain the composite probiotic powder beneficial to lipid-lowering metabolism.
Preferably, before step S1, bifidobacterium lactis B420, bifidobacterium lactis HN019, bifidobacterium breve B-3, lactobacillus acidophilus NCFM, lactobacillus rhamnosus 6594 and lactobacillus plantarum 299v are subjected to fermentation, freezing and drying treatment.
Preferably, in S6, the packaging shell is made of food-grade polyethylene material.
Compared with the prior art, the invention has the following beneficial effects:
1. in the application, by source adjustment, bifidobacterium lactis B420 and bifidobacterium lactis HN019 are used, the secretion of GPL-1 (glucagon-like peptide) of a human body is increased, ghrelin is reduced, and the appetite of consumers is further reduced; bifidobacterium animalis CP-9 and Lactobacillus rhamnosus bv-77 consume bile and bile acid in the digestive tract, reduce the decomposition of the bile and bile acid on fat, further reduce the absorption of the decomposed micromolecular fat by a human body, and further reduce the accumulation of the fat; bifidobacterium breve B-3 and Bifidobacterium animalis CP-9, and has effects of promoting lipodieresis in liver, reducing visceral fat, and inhibiting weight gain.
2. In the application, through the use of the multiple probiotics in a matched manner, and the composite probiotic powder and the plant active ingredients are scientifically and reasonably used in a matched manner, the generation of fat in the body can be effectively reduced, the types and the quantity of probiotics can be increased, and the growth of harmful bacteria can be inhibited, so that the selective regulation effect on the intestinal flora is achieved, the stability and the weight-losing effect of the probiotic composition are improved, and the weight-losing effect is remarkable and is suitable for wide crowds.
3. In this application, freeze-drying, triple embedding and evacuation nitrogenize technique have been used, make the bacterial can not take place the degeneration or lose life vigor, oxygen and moisture index in the help control product inner packing, simultaneously, adopted food level polyethylene packaging shell, effectively blocked external stimulus such as light, heat to preserve the probiotic activity better, guarantee the quality of product in the shelf life.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.
Example 1
The embodiment provides composite probiotic powder beneficial to lipid-lowering metabolism, which comprises the following raw materials in parts by weight: 1 part of probiotic powder, 2 parts of probiotic powder, 0.01 part of bifidobacterium lactis B420, 0.01 part of bifidobacterium lactis HN019, 0.01 part of bifidobacterium breve B-3.01 part, 0.01 part of lactobacillus acidophilus NCFM, 0.01 part of lactobacillus rhamnosus 6594, 0.01 part of lactobacillus plantarum 299v, 0.01 part of potato extract, 0.01 part of flammulina velutipes powder and 0.01 part of white kidney bean extract, wherein the number of viable bacteria of each strain is 2 multiplied by 10 10 CFU/g, various probiotics are used in a matching way, so that the lipid-lowering health-care tea has good lipid-lowering and metabolism-improving effects, is remarkable in weight-losing effect and is suitable for wide crowds;
the probiotic powder 1 comprises the following raw materials in parts by weight: 40 parts of resistant dextrin, 4 parts of xylo-oligosaccharide, 2 parts of erythritol, 34 parts of cranberry fruit powder, 13.3 parts of lactobacillus plantarum N, 0.01 part of lactobacillus rhamnosus LRa05, 0.2 part of pediococcus acidilactici CCFM7902, 80.04 parts of bifidobacterium lactis Bla, 26 parts of fructo-oligosaccharide and 20 parts of stachyose;
wherein the probiotic powder 2 comprises the following raw materials in parts by weight: bifidobacterium animalis CP-9.01 parts, fructo-oligosaccharide 12 parts, lactobacillus rhamnosus bv-77.04 parts;
the embodiment also provides a preparation method of the composite probiotic powder for helping lipid-lowering metabolism, which comprises the following steps:
s1, adding distilled water into a stirring kettle, adding probiotic powder 1, probiotic powder 2, bifidobacterium lactis B420, bifidobacterium lactis HN019, bifidobacterium breve B-3, lactobacillus acidophilus NCFM, lactobacillus rhamnosus 6594, lactobacillus plantarum 299v, a potato extract, flammulina velutipes powder and a white kidney bean extract into the stirring kettle one by one, stirring clockwise in the adding process at the rotation speed of 100r/min, continuously stirring for 26min after the adding is finished at the rotation speed of 160r/min to obtain a first mixed raw material, and fully mixing various raw materials to uniformly distribute various strains, wherein before the step S1, fermenting, freezing and drying bifidobacterium lactis B420, lactobacillus lactis HN019, bifidobacterium breve B-3, bifidobacterium acidophilus NCFM, lactobacillus rhamnosus 6594 and lactobacillus plantarum 299 v;
s2, adjusting the temperature of a freeze drying oven to 0 ℃, adding the mixed raw material I into the drying oven for freeze drying, wherein the freeze drying temperature is-40 ℃, the pressure of the freeze drying oven is 1Pa, and the freeze drying time is 18h, and the freeze drying is carried out to ensure that the dried material can keep the original chemical composition and physical properties;
s3, putting the freeze-dried mixed raw material I into a granulator, and extruding and granulating the mixed raw material I until the particle size is 20 meshes to obtain a powder raw material I;
s4, grinding the powder raw material I for 2 hours by using a ball mill, and after grinding is finished, screening by using a vibration screening machine to obtain a powder raw material II with the particle size of 160 meshes;
s5, processing the powder raw material II through a triple embedding technology to obtain powder particles, wherein the triple embedding technology enables the composite probiotic powder to have a directional slow-release controlled-release effect, so that the composite probiotic powder is not damaged by gastric acid and bile before reaching an intestinal tract and can be absorbed by the intestinal tract, and the effect of contributing to lipid-lowering metabolism is further realized;
s6, packaging the powder particles into a packaging shell through a packaging machine, and vacuumizing and filling nitrogen into the packaging shell, wherein in S6, the packaging shell is made of food-grade polyethylene materials, external stimulation such as light, heat and the like is effectively blocked, so that the activity of probiotics is better preserved, the quality of products in a shelf life is guaranteed, the water content of the products is controlled to be 3%, and the oxygen content is controlled to be 1%, so that the composite probiotic powder beneficial to lipid-lowering metabolism is obtained.
Example 2
The embodiment provides composite probiotic powder beneficial to lipid-lowering metabolism, which comprises the following raw materials in parts by weight: 1 92 parts of probiotic powder, 2 parts of probiotic powder, 0.5 part of bifidobacterium lactis B420, 0.5 part of bifidobacterium lactis HN019, 0.5 part of bifidobacterium breve B-3.5 parts, 0.5 part of lactobacillus acidophilus NCFM, 0.5 part of lactobacillus rhamnosus 6594, 0.5 part of lactobacillus plantarum 299v, 0.5 part of potato extract, 0.5 part of flammulina velutipes powder and 0.5 part of white kidney bean extract, wherein the number of viable bacteria of each strain is 3 multiplied by 10 10 CFU/g, various probiotics are used in a matched mode, the lipid-lowering and metabolism-improving effects are good, the weight-losing effect is obvious, and the weight-losing tea is suitable for wide crowds;
wherein the probiotic powder 1 comprises the following raw materials in parts by weight: 41 parts of resistant dextrin, 5 parts of xylo-oligosaccharide, 3 parts of erythritol, 35 parts of cranberry fruit powder, 13.4 parts of lactobacillus plantarum N, 0.02 part of lactobacillus rhamnosus LRa05, 0.3 part of pediococcus acidilactici CCFM7902, 80.05 parts of bifidobacterium lactis Bla, 27 parts of fructo-oligosaccharide and 21 parts of stachyose;
wherein the probiotic powder 2 comprises the following raw materials in parts by weight: bifidobacterium animalis CP-9.02 parts, fructo-oligosaccharide 13 parts, and Lactobacillus rhamnosus bv-77.05 parts;
the embodiment also provides a preparation method of the composite probiotic powder for helping lipid-lowering metabolism, which comprises the following steps:
s1, adding distilled water into a stirring kettle, adding probiotic powder 1, probiotic powder 2, bifidobacterium lactis B420, bifidobacterium lactis HN019, bifidobacterium breve B-3, lactobacillus acidophilus NCFM, lactobacillus rhamnosus 6594, lactobacillus plantarum 299v, a potato extract, flammulina velutipes powder and a white kidney bean extract into the stirring kettle one by one, stirring clockwise in the adding process at a rotation speed of 105r/min, continuously stirring for 27min after the adding is finished, and at a rotation speed of 165r/min to obtain a mixed raw material I, and fully mixing various raw materials to uniformly distribute various strains, wherein before the step S1, the bifidobacterium lactis B420, the bifidobacterium lactis HN019, the bifidobacterium breve B-3, the lactobacillus acidophilus NCFM, the lactobacillus rhamnosus 6594 and the lactobacillus plantarum 299v are fermented, frozen and dried;
s2, adjusting the temperature of a freeze drying oven to 1 ℃, adding the mixed raw material I into the drying oven for freeze drying, wherein the freeze drying temperature is-39 ℃, the pressure of the freeze drying oven is 4Pa, and the freeze drying time is 19h, and the freeze drying is carried out to ensure that the dried material can keep the original chemical composition and physical properties;
s3, putting the freeze-dried mixed raw material I into a granulator, and extruding and granulating the mixed raw material I until the particle size is 25 meshes to obtain a powder raw material I;
s4, grinding the powder raw material I through a ball mill for 2.5 hours, and after grinding is finished, screening through a vibration screening machine to obtain a powder raw material II with the particle size of 170 meshes;
s5, treating the powder raw material II through a triple embedding technology to obtain powder particles, wherein the triple embedding technology enables the composite probiotic powder to have a directional slow-release controlled-release effect, so that the composite probiotic powder is not damaged by gastric acid and bile before reaching the intestinal tract and can be absorbed by the intestinal tract, and the effect of contributing to lipid reduction and metabolism is further achieved;
s6, packaging the powder particles into a packaging shell through a packaging machine, and vacuumizing and filling nitrogen into the packaging shell, wherein in S6, the packaging shell is made of food-grade polyethylene materials and effectively prevents external stimulation such as light, heat and the like, so that the activity of probiotics is better preserved, the quality of products in shelf life is guaranteed, the water content of the products is controlled to be 4%, and the oxygen content is controlled to be 1.2%, and the composite probiotic powder beneficial to lipid-lowering metabolism is obtained.
Example 3
The embodiment provides composite probiotic powder beneficial to lipid-lowering metabolism, which comprises the following raw materials in parts by weight: 1 part of probiotic powder, 2 parts of bifidobacterium lactis B420, 1 part of bifidobacterium lactis HN019, and 1 part of brevibacterium1 part of bifidobacterium B-3, 1 part of lactobacillus acidophilus NCFM, 6594 parts of lactobacillus rhamnosus, 299v 1 part of lactobacillus plantarum, 1 part of potato extract, 1 part of flammulina velutipes powder and 1 part of white kidney bean extract, wherein the number of viable bacteria of each strain is 4 multiplied by 10 10 CFU/g, various probiotics are used in a matching way, so that the lipid-lowering health-care tea has good lipid-lowering and metabolism-improving effects, is remarkable in weight-losing effect and is suitable for wide crowds;
wherein the probiotic powder 1 comprises the following raw materials in parts by weight: 42 parts of resistant dextrin, 6 parts of xylo-oligosaccharide, 4 parts of erythritol, 36 parts of cranberry fruit powder, 0.5 part of lactobacillus plantarum N, 0.03 part of lactobacillus rhamnosus LRa05, 0.4 part of pediococcus acidilactici CCFM7902, 0.6 part of bifidobacterium lactis Bla, 28 parts of fructo-oligosaccharide and 22 parts of stachyose;
wherein the probiotic powder 2 comprises the following raw materials in parts by weight: bifidobacterium animalis CP-9.3 parts, fructo-oligosaccharide 14 parts, and Lactobacillus rhamnosus bv-77.06 parts;
the embodiment also provides a preparation method of the composite probiotic powder for helping lipid-lowering metabolism, which comprises the following steps:
s1, adding distilled water into a stirring kettle, adding probiotic powder 1, probiotic powder 2, bifidobacterium lactis B420, bifidobacterium lactis HN019, bifidobacterium breve B-3, lactobacillus acidophilus NCFM, lactobacillus rhamnosus 6594, lactobacillus plantarum 299v, a potato extract, flammulina velutipes powder and a white kidney bean extract into the stirring kettle one by one, stirring clockwise in the adding process at the rotation speed of 110r/min, continuously stirring for 28min after the adding is finished at the rotation speed of 170r/min to obtain a mixed raw material I, and fully mixing various raw materials to uniformly distribute various strains, wherein before the step S1, the bifidobacterium lactis B420, the bifidobacterium lactis HN019, the bifidobacterium breve B-3, the lactobacillus acidophilus NCFM, the lactobacillus rhamnosus 6594 and the lactobacillus plantarum 299v are fermented, frozen and dried;
s2, adjusting the temperature of a freeze drying oven to 2 ℃, adding the mixed raw material I into the drying oven for freeze drying, wherein the freeze drying temperature is-38 ℃, the pressure of the freeze drying oven is 5Pa, and the freeze drying time is 20 hours, and the freeze drying enables the dried material to keep the original chemical composition and physical properties;
s3, putting the freeze-dried mixed raw material I into a granulator, and extruding and granulating the mixed raw material I until the particle size is 30 meshes to obtain a powder raw material I;
s4, grinding the powder raw material I for 3 hours by using a ball mill, and after grinding is finished, screening by using a vibration screening machine to obtain a powder raw material II with the particle size of 180 meshes;
s5, processing the powder raw material II through a triple embedding technology to obtain powder particles, wherein the triple embedding technology enables the composite probiotic powder to have a directional slow-release controlled-release effect, so that the composite probiotic powder is not damaged by gastric acid and bile before reaching an intestinal tract and can be absorbed by the intestinal tract, and the effect of contributing to lipid-lowering metabolism is further realized;
s6, packaging the powder particles into a packaging shell through a packaging machine, and vacuumizing and filling nitrogen into the packaging shell, wherein in S6, the packaging shell is made of food-grade polyethylene materials and effectively prevents external stimulation such as light, heat and the like, so that the activity of probiotics is better preserved, the quality of products in shelf life is guaranteed, the water content of the products is controlled to be 5%, and the oxygen content is controlled to be 1.4%, and the composite probiotic powder beneficial to lipid-lowering metabolism is obtained.
Example 4
The embodiment provides composite probiotic powder beneficial to lipid-lowering metabolism, which comprises the following raw materials in parts by weight: 1 part of probiotic powder, 2 parts of probiotic powder, 420 parts of bifidobacterium lactis, 2 parts of bifidobacterium lactis HN019, 2 parts of bifidobacterium breve B-3 parts, 2 parts of lactobacillus acidophilus NCFM, 6594 parts of lactobacillus rhamnosus, 299v 2 parts of lactobacillus plantarum, 2 parts of potato extract, 2 parts of flammulina velutipes powder and 2 parts of white kidney bean extract, wherein the number of live bacteria of each strain is 6 multiplied by 10 10 CFU/g, various probiotics are used in a matching way, so that the lipid-lowering health-care tea has good lipid-lowering and metabolism-improving effects, is remarkable in weight-losing effect and is suitable for wide crowds;
the probiotic powder 1 comprises the following raw materials in parts by weight: 44 parts of resistant dextrin, 8 parts of xylo-oligosaccharide, 6 parts of erythritol, 38 parts of cranberry fruit powder, 0.7 part of lactobacillus plantarum N, 0.05 part of lactobacillus rhamnosus LRa, 0.6 part of pediococcus acidilactici CCFM7902, 80.08 parts of bifidobacterium lactis Bla, 30 parts of fructo-oligosaccharide and 24 parts of stachyose;
the probiotic powder 2 comprises the following raw materials in parts by weight: bifidobacterium animalis CP-9.05 parts, fructo-oligosaccharide 16 parts, and Lactobacillus rhamnosus bv-77.08 parts;
the embodiment also provides a preparation method of the composite probiotic powder for helping lipid-lowering metabolism, which comprises the following steps:
s1, adding distilled water into a stirring kettle, adding probiotic powder 1, probiotic powder 2, bifidobacterium lactis B420, bifidobacterium lactis HN019, bifidobacterium breve B-3, lactobacillus acidophilus NCFM, lactobacillus rhamnosus 6594, lactobacillus plantarum 299v, a potato extract, flammulina velutipes powder and a white kidney bean extract into the stirring kettle one by one, stirring clockwise in the adding process at the rotation speed of 120r/min, continuously stirring for 30min after the adding is finished at the rotation speed of 180r/min to obtain a first mixed raw material, and fully mixing various raw materials to uniformly distribute various strains, wherein before the step S1, fermenting, freezing and drying bifidobacterium lactis B420, lactobacillus lactis HN019, bifidobacterium breve B-3, bifidobacterium acidophilus NCFM, lactobacillus rhamnosus 6594 and lactobacillus plantarum 299 v;
s2, adjusting the temperature of a freeze drying oven to 4 ℃, adding the mixed raw material I into the drying oven for freeze drying, wherein the freeze drying temperature is-36 ℃, the pressure of the freeze drying oven is 9Pa, and the freeze drying time is 22h, and the freeze drying enables the dried material to keep the original chemical composition and physical properties;
s3, putting the freeze-dried mixed raw material I into a granulator, and extruding and granulating the mixed raw material I until the particle size is 40 meshes to obtain a powder raw material I;
s4, grinding the powder raw material I for 4 hours by using a ball mill, and after grinding is finished, screening by using a vibration screening machine to obtain a powder raw material II with the particle size of 200 meshes;
s5, processing the powder raw material II through a triple embedding technology to obtain powder particles, wherein the triple embedding technology enables the composite probiotic powder to have a directional slow-release controlled-release effect, so that the composite probiotic powder is not damaged by gastric acid and bile before reaching an intestinal tract and can be absorbed by the intestinal tract, and the effect of contributing to lipid-lowering metabolism is further realized;
s6, packaging the powder particles into a packaging shell through a packaging machine, and vacuumizing and filling nitrogen into the packaging shell, wherein in S6, the packaging shell is made of food-grade polyethylene materials, external stimulation such as light, heat and the like is effectively blocked, so that the activity of probiotics is better preserved, the quality of products in a shelf life is guaranteed, the water content of the products is controlled to be 7%, and the oxygen content is controlled to be 1.8%, so that the composite probiotic powder beneficial to lipid-lowering metabolism is obtained.
The beneficial effects of the drug of the present invention are further illustrated by the following test examples.
General data:
100 obese adult patients are selected, each patient takes the product twice a day with 2g of warm boiled water below 40 ℃ after meals for 28 days continuously.
Diagnostic criteria:
obese patients had weight loss.
3. The treatment effect is as follows: (see the following Table)
Item Effective/human Invalid/human Effective rate/%
Obesity 98 2 98
As can be seen from the data in the table above, after the obesity patient takes the product, the effective rate of the product for the obesity patient is 98%, and the effect is very good.
The following are individual examples of the administration of the products of the invention:
1. wholy, 28 years old, female, pre-dose symptoms: no obvious symptoms, and only overweight. After taking the product: weight loss.
2. Payment, 32 years old, female, pre-administration symptoms: overweight is associated with symptoms of shortness of breath, joint pain, muscle soreness, reduced physical activity, and anxiety. After taking the product: weight loss, body fat loss, relief of symptoms of gas urgency, joint pain, muscle soreness, increased physical activity and reduced symptoms of anxiety.
3. Some of matacia, 34 years old, male, with symptoms before administration: overweight, accompanied by dyslipidemia and hypertension. After taking the product: weight loss, dyslipidemia and relief of symptoms of hypertension.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (7)

1. The composite probiotic powder for assisting in lipid-lowering metabolism is characterized by comprising the following raw materials in parts by weight: 190-98 parts of probiotic powder, 21-5 parts of probiotic powder, 0.01-2 parts of bifidobacterium lactis B420, 0.01-2 parts of bifidobacterium lactis HN0190.01-2 parts of bifidobacterium breve B-30.01-2 parts of lactobacillus acidophilus NCFM0.01-2 parts of lactobacillus rhamnosus 65940.01-2 parts, 0.01-2 parts of lactobacillus plantarum 299v, 0.01-2 parts of potato extract, 0.01-2 parts of flammulina velutipes powder and 0.01-2 parts of white kidney bean extract.
2. The composite probiotic powder for assisting lipid-lowering metabolism according to claim 1, wherein the probiotic powder 1 comprises the following raw materials in parts by weight: 40-44 parts of resistant dextrin, 4-8 parts of xylo-oligosaccharide, 2-6 parts of erythritol, 34-38 parts of cranberry fruit powder, 130.3-0.7 part of lactobacillus plantarum N, 0.01-0.05 part of lactobacillus rhamnosus LRa050, 0.2-0.6 part of pediococcus acidilactici CCFM79020, 0.04-0.08 part of bifidobacterium lactis Bla, 26-30 parts of fructo-oligosaccharide and 20-24 parts of stachyose.
3. The composite probiotic powder for assisting lipid-lowering metabolism according to claim 2, wherein the probiotic powder 2 comprises the following raw materials in parts by weight: bifidobacterium animalis CP-90.01-0.05 parts, lactobacillus rhamnosus bv-770.04-0.08 parts and fructo-oligosaccharide 12-16 parts.
4. The composite probiotic powder for assisting lipid-lowering metabolism according to claim 3, wherein the number of viable bacteria of each strain is 2-6 x 10 10 CFU/g。
5. The method for preparing a composite probiotic powder for assisting the metabolism of lipid lowering according to any of claims 1 to 4, characterized in that it comprises the following steps:
s1, adding distilled water into a stirring kettle, adding probiotic powder 1, probiotic powder 2, bifidobacterium lactis B420, bifidobacterium lactis HN019, bifidobacterium breve B-3, lactobacillus acidophilus NCFM, lactobacillus rhamnosus 6594, lactobacillus plantarum 299v, a potato extract, flammulina velutipes powder and a white kidney bean extract into the stirring kettle one by one, stirring clockwise in the adding process at the rotating speed of 100-120r/min, continuing stirring for 26-30min after the adding is finished, and at the rotating speed of 160-180r/min to obtain a first mixed raw material;
s2, adjusting the temperature of a freeze drying oven to 0-4 ℃, adding the first mixed raw material into the drying oven for freeze drying, wherein the freeze drying temperature is-40 ℃ to-36 ℃, the pressure of the freeze drying oven is 1-9Pa, and the freeze drying time is 18-22h;
s3, putting the freeze-dried mixed raw material I into a granulator, and extruding and granulating the mixed raw material I until the particle size is 20-40 meshes to obtain a powder raw material I;
s4, grinding the powder raw material I for 2-4h by using a ball mill, and screening by using a vibration screening machine after grinding is finished to obtain a powder raw material II with the particle size of 160-200 meshes;
s5, treating the powder raw material II through a triple embedding technology to obtain powder particles;
s6, packaging the powder particles into a packaging shell through a packaging machine, vacuumizing and filling nitrogen into the packaging shell, and controlling the water content of the product to be 3% -7% and the oxygen content to be 1% -1.8% to obtain the composite probiotic powder beneficial to lipid-lowering metabolism.
6. The method for preparing composite probiotic powder for assisting lipid-lowering metabolism according to claim 5, wherein, prior to step S1, fermentation, freezing and drying treatment are performed on Bifidobacterium lactis B420, bifidobacterium lactis HN019, bifidobacterium breve B-3, lactobacillus acidophilus NCFM, lactobacillus rhamnosus 6594 and Lactobacillus plantarum 299 v.
7. The method for preparing composite probiotic powder for assisting lipid-lowering metabolism according to claim 5, wherein in S6, food-grade polyethylene material is adopted as a packaging shell.
CN202211117988.0A 2022-09-14 2022-09-14 Composite probiotic powder beneficial to lipid-lowering metabolism and preparation method thereof Pending CN115486542A (en)

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Application publication date: 20221220