CN1154730C - 用于结核病诊断的化合物和方法 - Google Patents

用于结核病诊断的化合物和方法 Download PDF

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Publication number
CN1154730C
CN1154730C CNB961974672A CN96197467A CN1154730C CN 1154730 C CN1154730 C CN 1154730C CN B961974672 A CNB961974672 A CN B961974672A CN 96197467 A CN96197467 A CN 96197467A CN 1154730 C CN1154730 C CN 1154730C
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CNB961974672A
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CN1200146A (zh
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Sg
S·G·里德
W
Y·A·W·斯克凯
¡
D·C·笛勒隆
-
A·卡穆普斯-尼托
R·胡格藤
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T·H·威德维克
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D·R·特瓦德茨克
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Corixa Corp
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Corixa Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
CNB961974672A 1995-09-01 1996-08-30 用于结核病诊断的化合物和方法 Expired - Lifetime CN1154730C (zh)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US52343595A 1995-09-01 1995-09-01
US08/523,435 1995-09-01
US53213695A 1995-09-22 1995-09-22
US08/532,136 1995-09-22
US62028096A 1996-03-22 1996-03-22
US08/620,280 1996-03-22
US65880096A 1996-06-05 1996-06-05
US08/658,800 1996-06-05
US68057396A 1996-07-12 1996-07-12
US08/680,573 1996-07-12

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA2004100351841A Division CN1554664A (zh) 1995-09-01 1996-08-30 用于结核病诊断的化合物和方法

Publications (2)

Publication Number Publication Date
CN1200146A CN1200146A (zh) 1998-11-25
CN1154730C true CN1154730C (zh) 2004-06-23

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ID=27541833

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB961974672A Expired - Lifetime CN1154730C (zh) 1995-09-01 1996-08-30 用于结核病诊断的化合物和方法
CNA2004100351841A Pending CN1554664A (zh) 1995-09-01 1996-08-30 用于结核病诊断的化合物和方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA2004100351841A Pending CN1554664A (zh) 1995-09-01 1996-08-30 用于结核病诊断的化合物和方法

Country Status (13)

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EP (2) EP2154248B1 (OSRAM)
JP (1) JPH11514217A (OSRAM)
CN (2) CN1154730C (OSRAM)
AT (2) ATE530671T1 (OSRAM)
AU (1) AU7158796A (OSRAM)
CA (1) CA2230927A1 (OSRAM)
CY (1) CY2618B2 (OSRAM)
DE (1) DE69636075D1 (OSRAM)
DK (1) DK2154248T3 (OSRAM)
ES (1) ES2378051T3 (OSRAM)
MX (1) MX9801687A (OSRAM)
PT (1) PT2154248E (OSRAM)
WO (1) WO1997009429A2 (OSRAM)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
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US6641814B1 (en) 1997-04-02 2003-11-04 Statens Serum Institut Nucleic acids fragments and polypeptide fragments derived from M. tuberculosis
US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6592877B1 (en) 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6290969B1 (en) 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
TR199901569T2 (xx) * 1996-10-11 2000-12-21 Corixa Corporation T�berk�lozun te�hisi i�in bile�ikler ve y�ntemler.
US6627198B2 (en) 1997-03-13 2003-09-30 Corixa Corporation Fusion proteins of Mycobacterium tuberculosis antigens and their uses
US6350456B1 (en) 1997-03-13 2002-02-26 Corixa Corporation Compositions and methods for the prevention and treatment of M. tuberculosis infection
US6544522B1 (en) * 1998-12-30 2003-04-08 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
ATE370236T1 (de) * 1997-04-02 2007-09-15 Statens Seruminstitut Nukleinsäure- und polypeptidfragmente von m. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
US6613881B1 (en) * 1997-05-20 2003-09-02 Corixa Corporation Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
US6555653B2 (en) * 1997-05-20 2003-04-29 Corixa Corporation Compounds for diagnosis of tuberculosis and methods for their use
US6436409B1 (en) * 1997-07-16 2002-08-20 Institut Pasteur Polynucleotide functionally coding for the LHP protein from Mycobacterium tuberculosis, its biologically active derivative fragments, as well as methods using the same
EP1484405A1 (en) * 1997-11-10 2004-12-08 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from M. Tuberculosis
CA2319380A1 (en) * 1997-11-10 1999-05-20 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from m. tuberculosis
EP0921397A1 (en) * 1997-12-08 1999-06-09 Kreatech Biotechnology B.V. A method for identifying a mycobacterium species
KR100692227B1 (ko) * 1998-04-07 2007-03-09 코릭사 코포레이션 마이코박테리움 튜베르쿨로시스 항원의 융합 단백질 및이의 용도
US6183957B1 (en) * 1998-04-16 2001-02-06 Institut Pasteur Method for isolating a polynucleotide of interest from the genome of a mycobacterium using a BAC-based DNA library application to the detection of mycobacteria
GB9808720D0 (en) * 1998-04-23 1998-06-24 Smithkline Beecham Biolog Novel compounds
JP2002522067A (ja) * 1998-08-10 2002-07-23 カイロン コーポレイション 一群の抗原を発現する操作された抗原提示細胞およびその使用
US6465633B1 (en) 1998-12-24 2002-10-15 Corixa Corporation Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
US7932373B1 (en) 1999-05-04 2011-04-26 University Of Medicine And Dentistry Of New Jersey Proteins expressed by mycobacterium tuberculosis and not by BCG and their use as diagnostic reagents and vaccines
US7009042B1 (en) 1999-10-07 2006-03-07 Corixa Corporation Methods of using a Mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of the heterologous proteins
ATE354663T1 (de) * 1999-10-07 2007-03-15 Corixa Corp Eine mycobacterium tuberculosis kodierende sequenz zur expression von heterologen proteinen
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
AU2001241738A1 (en) 2000-02-25 2001-09-03 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
EP1542732B1 (en) 2000-06-20 2009-09-16 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
WO2003070187A2 (en) 2002-02-15 2003-08-28 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US20040072262A1 (en) 2002-10-11 2004-04-15 Montero-Julian Felix A. Methods and systems for detecting MHC class I binding peptides
WO2005077003A2 (en) * 2004-02-09 2005-08-25 Friedman Richard L Pili from mycobacterium tuberculosis
EP1781313A4 (en) * 2004-06-17 2009-08-26 Beckman Coulter Inc MYCOBACTERIUM TUBERCULOSIS EPITOPES AND METHODS OF USE
JP4838259B2 (ja) 2004-11-16 2011-12-14 クルセル ホランド ベー ヴェー 組み換えウイルスベクターを含む多価ワクチン
ES2381492T3 (es) 2005-04-29 2012-05-28 Glaxosmithkline Biologicals Sa Procedimiento de prevención o tratamiento de infección por M. tuberculosis
RU2473095C2 (ru) * 2007-12-28 2013-01-20 БиЭл КО., ЛТД Анализ иммунодетекции комплекса mycobacterium tuberculosis
WO2011092253A1 (en) 2010-01-27 2011-08-04 Glaxosmithkline Biologicals S.A. Modified tuberculosis antigens
SG190731A1 (en) 2010-12-14 2013-07-31 Glaxosmithkline Biolog Sa Mycobacterium antigenic composition
EP3415919B1 (en) * 2012-02-07 2020-07-29 Intuitive Biosciences Inc. Mycobacterium tuberculosis specific peptides for detection of infection or immunization in non-human primates
KR20170071507A (ko) 2014-10-23 2017-06-23 퀴아젠 사이언시스, 엘엘씨 펩티드 조성물 및 그의 용도
CN106008685A (zh) * 2016-05-18 2016-10-12 首都医科大学附属北京胸科医院 Trxc抗体识别的抗原多肽及其用途
CN110073215B (zh) * 2016-09-22 2024-04-30 佩斯诊断公司 结核分枝杆菌蛋白诊断测定和结核病检测和诊断装置
EP3399312A1 (fr) 2017-05-05 2018-11-07 Biomérieux Procédé de détection d'une réponse cellulaire immune
ES2933132T3 (es) 2017-05-05 2023-02-01 Biomerieux Sa Procedimiento para detectar una respuesta celular inmune
KR20220052937A (ko) * 2019-07-30 2022-04-28 디엔에이 스크립트 폴리(a) 및 폴리(u) 중합효소를 사용한 폴리뉴클레오타이드의 주형-부재 효소적 합성
CN111269856B (zh) * 2020-02-19 2021-11-30 首都医科大学附属北京胸科医院 一种分离和/或富集结核分枝杆菌的方法

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US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
EP0419355B1 (en) * 1989-09-19 2000-02-09 N.V. Innogenetics S.A. Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis
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US5330754A (en) * 1992-06-29 1994-07-19 Archana Kapoor Membrane-associated immunogens of mycobacteria
US5359681A (en) 1993-01-11 1994-10-25 University Of Washington Fiber optic sensor and methods and apparatus relating thereto
DK79893D0 (da) * 1993-07-02 1993-07-02 Statens Seruminstitut New vaccine
DK79793D0 (da) * 1993-07-02 1993-07-02 Statens Seruminstitut Diagnostic test

Also Published As

Publication number Publication date
WO1997009429A2 (en) 1997-03-13
DK2154248T3 (da) 2012-01-30
WO1997009429A3 (en) 1997-07-17
MX9801687A (es) 1998-11-29
ATE324445T1 (de) 2006-05-15
ATE530671T1 (de) 2011-11-15
EP2154248B1 (en) 2011-10-26
CA2230927A1 (en) 1997-03-13
PT2154248E (pt) 2012-01-16
AU7158796A (en) 1997-03-27
CN1554664A (zh) 2004-12-15
CY2618B2 (OSRAM) 2012-10-24
EP0850305B1 (en) 2006-04-26
EP0850305A2 (en) 1998-07-01
JPH11514217A (ja) 1999-12-07
CN1200146A (zh) 1998-11-25
ES2378051T3 (es) 2012-04-04
DE69636075D1 (de) 2006-06-01
EP2154248A1 (en) 2010-02-17

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