CN115462526A - Weight management composition containing plant exosomes - Google Patents
Weight management composition containing plant exosomes Download PDFInfo
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- CN115462526A CN115462526A CN202211168565.1A CN202211168565A CN115462526A CN 115462526 A CN115462526 A CN 115462526A CN 202211168565 A CN202211168565 A CN 202211168565A CN 115462526 A CN115462526 A CN 115462526A
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the technical field of foods, and relates to a weight management composition containing plant exosomes. The weight management composition comprises the following effective components in parts by mass: 10-20 parts of plant exosomes, 6-12 parts of medium chain triglyceride, 5-15 parts of plant fat powder, 2-8 parts of milk mineral salt and 8-14 parts of seaweed extract. The invention combines the plant exocrine, medium chain triglyceride, the plant fat powder, the milk mineral salt and the seaweed extract to prepare the weight management composition, has the synergistic effect on reducing the fat rate and improving the body type, solves the problems of malnutrition and the like easily caused by common weight management foods, and can also promote metabolism and improve cardiovascular health.
Description
Technical Field
The invention belongs to the technical field of food, and relates to a weight management composition containing plant exosomes.
Background
With the continuous development and progress of society, the living standard of people is gradually improved, and the living style is changed day by day, so that overweight and obese people are increased greatly. The harm of weight growth to the health and the psychology of the group exceeds the imagination of people, and becomes a social problem of general attention. According to the WHO report, overweight and obesity seriously affect human health, and can cause coronary heart disease, ischemic stroke, cancer, hypertension, dyslipidemia, type 2 diabetes, arthropathy, sleep apnea, asthma and other chronic diseases. The importance of weight management goes undoubtedly, but how to effectively and thoroughly carry out the management for a long time to achieve long-term weight control and reduce or eliminate the risk factor is a serious issue for researchers at home and abroad at present.
The exosome is an extracellular vesicle with the diameter of 40-100nm secreted by eukaryotic cells, and is a vesicle released from cells after intracellular MVB is fused with PM. The plant exosome has a similar morphological structure to the animal exosome, has a phospholipid bilayer structure, contains protein and micro RNA, and is in a saucer shape or a cup shape. The existing research shows that the plant exosome has certain functions in aspects of plant defense immunity, interspecies communication, mammal inflammatory reaction treatment, drug carrier and the like, and the development prospect of the plant exosome is very wide in the aspects.
Medium Chain Triglycerides (MCT) are saturated fatty acids with a carbon chain length of 8-12, naturally occurring mainly in coconut oil, but in other natural foods in small amounts, with a caloric value of 34.73kJ (8.3 kcal)/g. The effect of MCT on protein metabolism is not yet known. Experiments show that MCT can increase protein retention and protein utilization rate of chickens more than LCT under the same feeding condition, and has strong weight increasing effect; however, in another chicken experiment, MCT-containing feed reduced chicken energy utilization and protein retention, but protein utilization was not significantly altered.
The natural vegetable fat powder is water soluble powdered oil prepared with vegetable oil, milk protein, starch syrup as main material, emulsifier, stabilizer, flavoring agent and other supplementary material and through emulsifying, homogenizing and spray drying. Has the characteristics of grease oxidation prevention, good fluidity, high nutritive value and the like. Contains abundant unsaturated fatty acids, wherein omega-3 and omega-6 fatty acids have the benefits of lowering blood pressure and cholesterol, preventing cardiovascular disease risk and increasing bone density, maintaining and optimizing brain health, eye health, etc.
The milk mineral salt is a nutritional supplement which is prepared by taking whey as a raw material and removing protein, lactose and other components, namely milk basic protein and is beneficial to absorption of a human body. The milk mineral salt can not only supplement calcium intake, but also has health promotion effects of lowering blood pressure and preventing arterial stenosis. Research has shown that milk mineral salts have the effects of increasing the biological availability of calcium, increasing bone density, reducing the risk of colon cancer and inhibiting hypertension.
The seaweed extract is a purely natural marine product, and the extracts of different types of seaweed have great difference. Generally speaking, the seaweed extract contains alginic acid, crude protein, various vitamins, enzymes and trace elements. The active substances of the seaweed extract mainly comprise cytokinin, betaine, auxin, seaweed polyphenol, abscisic acid, gibberellin, ethylene, polyamine and the like. The research shows that the seaweed extract has lipid-lowering and anti-oxidation effects on experimental hyperlipemia rat models.
At present, weight management products on the market are mainly weight management tea, sports weight management food, meal replacement weight management food and the like. The weight management food, in particular to meal replacement type weight management food, can replace middle and late meals to be eaten, can enhance satiety and can delay gastric emptying, so that the weight management effect is achieved, and more people can select to eat the weight management food for weight management. However, most of the current weight management foods are easy to cause the problems of malnutrition and the like, and are also easy to influence the metabolism and the cardiovascular health.
Disclosure of Invention
The present invention addresses the above-mentioned problems by providing a weight management composition comprising plant exosomes. The effective components of the weight management composition show synergistic effect in reducing fat rate and improving body shape. The weight management composition containing the plant exosomes solves the problems of malnutrition and the like easily caused by common weight management foods, and can also promote metabolism and improve cardiovascular health.
On one hand, the invention relates to a weight management composition containing plant exosomes, which comprises the following effective components in parts by mass: 10-20 parts of plant exosome, 6-12 parts of medium-chain triglyceride, 5-15 parts of plant fat powder, 2-8 parts of milk mineral salt and 8-14 parts of seaweed extract; preferably, the effective components comprise the following components in parts by mass: 15 parts of plant exosome, 10 parts of medium-chain triglyceride, 13 parts of plant fat powder, 6 parts of milk mineral salt and 10 parts of seaweed extract.
Further, in the weight management composition provided by the invention, the plant exosomes are one or a mixture of more of grape fruit cell exosomes, pomegranate exosomes, onion exosomes, horse tooth exosomes, asiatic pennywort exosomes, carrot exosomes, rose exosomes and daisy exosomes.
In the weight management composition provided by the invention, the seaweed extract is one of an undaria pinnatifida fat-soluble extract, a sargassum thunbergii fat-soluble extract and a dictyococcus divaricatus fat-soluble extract.
In another aspect, the invention relates to a food product comprising a weight management composition as provided by the invention and a dietetically acceptable adjuvant.
Further, the present invention provides the food wherein the dietetically acceptable auxiliary materials include oligosaccharides, antioxidants and sweeteners.
Further, in the food provided by the invention, the oligosaccharide is one or a mixture of fructo-oligosaccharide, galacto-oligosaccharide and xylo-oligosaccharide.
Further, in the food provided by the invention, the antioxidant is one or a mixture of vitamin C, vitamin E and glutathione.
Further, in the food provided by the invention, the sweetener is stevioside and/or erythritol.
Furthermore, in the food provided by the invention, the food is in a powder form.
Compared with the prior art, the invention has the following beneficial effects or advantages:
the invention combines the plant exocrine, medium chain triglyceride, the plant fat powder, the milk mineral salt and the seaweed extract to prepare the weight management composition, has the synergistic effect on reducing the fat rate and improving the body type, solves the problems of malnutrition and the like easily caused by common weight management foods, and can also promote metabolism and improve cardiovascular health. The invention adds the milk mineral salt and the seaweed extract, not only can enrich the taste of the food, but also can supplement calcium and various nutrient substances, and solves the health problems of malnutrition and the like caused by overhigh body fat rate while realizing the reduction of fat rate and the improvement of body shape.
Detailed Description
In order to make the technical solutions of the present invention better understood and enable those skilled in the art to practice the present invention, the following embodiments are further described, but the present invention is not limited to the following embodiments.
The experimental methods and the detection methods described in the following examples are all conventional methods unless otherwise specified; the test articles and materials, unless otherwise specified, are commercially available.
Example 1
This example provides the preparation of a weight management food (powder).
Preparing the undaria pinnatifida fat-soluble extract: washing off surface attachments of fresh undaria pinnatifida by using clear water, then scalding 10g of clean fresh seaweed in boiling water for 2-3 min to inactivate lipolytic enzymes in the seaweed, sucking water on the surface of a sample by using filter paper, putting about 5g of seaweed into a mortar, and adding a small amount of pickling sand for grinding.
The raw materials are prepared from, by mass, 3 parts of grape fruit cell exosome, 3 parts of pomegranate exosome, 4 parts of onion exosome, 6 parts of medium-chain triglyceride, 5 parts of plant fat powder, 2 parts of milk mineral salt, 8 parts of undaria pinnatifida fat-soluble extract, 1 part of fructo-oligosaccharide, 0.05 part of vitamin C and 0.01 part of stevioside.
The weight management composition (powder) is prepared by mixing the raw materials, grinding, sieving with a 50-mesh sieve, mixing, quantitatively packaging.
Example 2
This example provides the preparation of a weight management food (powder).
The preparation method of the sargassum thunbergii fat-soluble extract is the same as that in example 1, except that the raw material for preparation is fresh sargassum thunbergii.
Preparing raw materials, by mass, 5 parts of horse tooth exosomes, 5 parts of centella asiatica exosomes, 5 parts of carrot exosomes, 10 parts of medium-chain triglycerides, 13 parts of vegetable fat powder, 6 parts of milk mineral salt, 10 parts of sargassum thunbergii fat-soluble extract, 0.5 part of galacto-oligosaccharide, 0.01 part of vitamin E and 0.05 part of erythritol.
The weight management composition (powder) is prepared by mixing the raw materials, grinding, sieving with a 50-mesh sieve, mixing, quantitatively packaging.
Example 3
This example provides the preparation of a weight management food (powder).
The preparation method of the dictyocauline molt-soluble extract is the same as that in example 1, except that the raw material is fresh dictyocauline molt-soluble extract.
The raw materials are prepared from, by mass, 10 parts of rose exosomes, 10 parts of daisy exosomes, 12 parts of medium-chain triglycerides, 15 parts of plant fat powder, 8 parts of milk mineral salts, 14 parts of dictyota liposoluble extract, 0.8 part of xylo-oligosaccharides, 0.03 part of glutathione and 0.01 part of erythritol.
The weight management composition (powder) is prepared by mixing the raw materials, grinding, sieving with a 50-mesh sieve, mixing, quantitatively packaging.
Example 4
This example provides a test of a weight management composition comprising plant exosomes for reducing fat rate and improving body size.
120 subjects are taken as test subjects, athletes, long-term fitness persons and subjects with low body fat are excluded, after two weeks of preparation (without any medicaments or foods related to weight-loss management), the test is started, and the test subjects are divided into subjects with high body fat (male body fat is more than or equal to 20 percent and female body fat is more than or equal to 23 percent) and subjects with normal fat (male body fat is more than 15 percent and less than 20 percent and female body fat is more than 18 percent and less than 23 percent) according to the body fat rate. 120 subjects were divided into 3 groups of 40 persons, with the average distribution of subjects with high body fat and normal fat in each group, and the average distribution of male and female gender in each group.
Each group of subjects ingested the products of the different examples, 3 groups of products of examples 1-3, 2 times a day, 20g each time, and taken with 200mL warm water 2h after breakfast and 2h after lunch, respectively. The test was conducted for 3 months, and the weight, body fat, waist circumference, hip circumference and other indicators were recorded once a month to compare the changes before and after ingestion of the product.
TABLE 1 weight change results of the weight management foods provided in example 1
TABLE 2 weight change results of the weight management foods provided in example 2
TABLE 3 weight change results of taking the weight management food provided in example 3
As can be seen from tables 1 to 3, the weight management food provided by the present invention has significant fat-reducing rate and body-shaping effect, and among them, the subjects who took the weight management food provided in example 2 achieved the best fat-reducing rate and body-shaping effect.
Example 5
This example provides an animal trial of a weight management composition containing plant exosomes in reducing fat rate and improving body size.
Mice, SPF grade, male. The animals were acclimatized at an indoor temperature of 22 ℃ and a relative humidity of 60% for 7 days, and then given a high fat diet for 7 days. Grouping, the mice were randomly grouped into 10 mice each group, which were blank control group, example 1 group, example 2 group, example 3 group, plant exosome 1 control group, plant exosome 2 control group, plant exosome 3 control group, seaweed extract 1 control group, seaweed extract 2 control group, and seaweed extract 3 control group. Example 1 group gavage daily 0.25g of the weight management composition provided in example 1; example 2 group gavage daily 0.25g of the weight management composition provided in example 2; example 3 group gavage daily 0.25g of the weight management composition provided in example 3; the plant exosome 1 control group is irrigated with 0.25g of a mixture of grape fruit cell exosomes, pomegranate exosomes and onion exosomes every day, and the mixing ratio of the grape fruit cell exosomes, the pomegranate exosomes and the onion exosomes is 3; plant exosome 2 control group is irrigated with 0.25g of mixture of horse tooth exosomes, snowgrass exosomes and carrot exosomes every day, and the mixing ratio of the horse tooth exosomes, the snowgrass exosomes and the carrot exosomes is 1; plant exosome 3 control group was gavaged with 0.25g of a mixture of rose exosomes and daisy exosomes per day, and the mixing ratio of the rose exosomes and the daisy exosomes was 1 by mass ratio; the blank control group was gavaged daily with equal amount of clear water. During the test period, each group of mice is given normal diet, the weight average value of each group of mice is measured on the 0 th day, the 10 th day and the 30 th day respectively, and after the test on the 30 th day is finished, the mice are fasted for 12h, and the content of triglyceride in the blood serum of each group of mice is measured.
TABLE 4 results of mouse body weight changes
| Body weight/g | Day 0 | 10 days | 30 days |
| Blank control group | 25.20 | 30.13 | 40.33 |
| EXAMPLE 1 group | 25.05 | 27.94 | 32.56 |
| EXAMPLE 2 group | 25.20 | 27.84 | 32.04 |
| EXAMPLE 3 group | 25.22 | 27.91 | 32.39 |
| Plant exosome 1 control group | 25.34 | 29.17 | 34.59 |
| Plant exosome 2 control group | 25.06 | 28.71 | 34.40 |
| Plant exosome 3 control group | 25.68 | 29.36 | 35.35 |
| Seaweed extract 1 control group | 25.38 | 29.81 | 37.53 |
| Seaweed extract 2 control group | 25.49 | 29.87 | 37.99 |
| Seaweed extract 3 control group | 25.71 | 29.96 | 38.19 |
TABLE 5 results of triglyceride content variation
| Triglyceride (mmol/L) | |
| Blank control group | 1.14 |
| EXAMPLE 1 group | 0.75 |
| EXAMPLE 2 group | 0.72 |
| EXAMPLE 3 group | 0.74 |
| Plant exosome 1 control group | 0.89 |
| Plant exosome 2 control group | 0.90 |
| Plant exosome 3 control group | 0.82 |
| Seaweed extract 1 control group | 0.99 |
| Seaweed extract 2 control group | 0.98 |
| Seaweed extract 3 control group | 0.92 |
As can be seen from the results of table 4, the weight management food provided by the present invention has a significant effect of reducing the weight of mice, wherein the weight management food provided in example 2 has the best effect on the weight loss of mice. As can be seen from the results in table 5, the weight management food provided by the present invention has a significant lipid-lowering effect, and the weight management food provided in example 2 has the best effect on lowering lipid in mice.
As described above, the present invention can be preferably implemented, and the above-mentioned embodiments only describe the preferred embodiments of the present invention, and do not limit the scope of the present invention, and various changes and modifications of the technical solution of the present invention made by those skilled in the art without departing from the design spirit of the present invention shall fall within the protection scope defined by the present invention.
Claims (10)
1. A weight management composition containing plant exosomes is characterized by comprising the following effective components in parts by mass: 10-20 parts of plant exosome, 6-12 parts of medium-chain triglyceride, 5-15 parts of plant fat powder, 2-8 parts of milk mineral salt and 8-14 parts of seaweed extract.
2. The weight management composition according to claim 1, wherein the effective ingredients comprise, in parts by mass: 15 parts of plant exosome, 10 parts of medium-chain triglyceride, 13 parts of plant fat powder, 6 parts of milk mineral salt and 10 parts of seaweed extract.
3. The weight management composition of claim 1, wherein the plant exosomes are a mixture of one or more of grape fruit cell exosomes, pomegranate exosomes, onion exosomes, horse teeth exosomes, snowflake exosomes, carrot exosomes, rose exosomes, daisy exosomes.
4. The weight management composition of claim 1, wherein the seaweed extract is one of a lipid soluble extract of Undaria pinnatifida, a lipid soluble extract of Surgassum thunbergii, and a lipid soluble extract of Dictyotanus divaricata.
5. A food product comprising the weight management composition of any of claims 1-4 and a dietetically acceptable adjuvant.
6. The food product of claim 5, wherein the comestibly acceptable excipients comprise an oligosaccharide, an antioxidant, and a sweetener.
7. The food product of claim 6, wherein the oligosaccharide is a mixture of one or more of fructooligosaccharides, galactooligosaccharides and xylooligosaccharides.
8. The food product of claim 6, wherein the antioxidant is a blend of one or more of vitamin C, vitamin E, and glutathione.
9. The food product of claim 6, wherein the sweetener is a steviol glycoside and/or erythritol.
10. The food product of claim 6, wherein the food product is in the form of a powder.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024025934A1 (en) * | 2022-07-29 | 2024-02-01 | Abbott Laboratories | Methods for promoting healthy catch-up growth |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050003026A1 (en) * | 2002-08-14 | 2005-01-06 | Song-Hae Bok | Powder or extracts of plant leaves with anti-obesity effects and anti-obesity food comprising them |
| JP2013150635A (en) * | 2013-05-01 | 2013-08-08 | Hayashibara Co Ltd | Orally ingestible composition for diet |
| CN104643250A (en) * | 2015-02-14 | 2015-05-27 | 河南省摇太阳食品有限公司 | Solid beverage capable of bidirectionally regulating body weight and improving subhealth |
| CN110447906A (en) * | 2019-09-10 | 2019-11-15 | 江西人之初营养科技股份有限公司 | A kind of composition and preparation method thereof for helping to control weight |
| CN111034999A (en) * | 2019-12-31 | 2020-04-21 | 北京康比特体育科技股份有限公司 | Composition with sugar-resisting and weight-losing functions |
| CN111436609A (en) * | 2020-04-30 | 2020-07-24 | 东莞自然衡健康科技有限公司 | Product containing plant exosomes and resveratrol and preparation method thereof |
| CN113273694A (en) * | 2021-05-31 | 2021-08-20 | 东莞自然衡健康科技有限公司 | Weight management composition containing plant exosomes and preparation method thereof |
| CN113729211A (en) * | 2021-08-04 | 2021-12-03 | 北京斯利安健康科技有限公司 | Composition and preparation method and application thereof |
-
2022
- 2022-09-24 CN CN202211168565.1A patent/CN115462526A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050003026A1 (en) * | 2002-08-14 | 2005-01-06 | Song-Hae Bok | Powder or extracts of plant leaves with anti-obesity effects and anti-obesity food comprising them |
| JP2013150635A (en) * | 2013-05-01 | 2013-08-08 | Hayashibara Co Ltd | Orally ingestible composition for diet |
| CN104643250A (en) * | 2015-02-14 | 2015-05-27 | 河南省摇太阳食品有限公司 | Solid beverage capable of bidirectionally regulating body weight and improving subhealth |
| CN110447906A (en) * | 2019-09-10 | 2019-11-15 | 江西人之初营养科技股份有限公司 | A kind of composition and preparation method thereof for helping to control weight |
| CN111034999A (en) * | 2019-12-31 | 2020-04-21 | 北京康比特体育科技股份有限公司 | Composition with sugar-resisting and weight-losing functions |
| CN111436609A (en) * | 2020-04-30 | 2020-07-24 | 东莞自然衡健康科技有限公司 | Product containing plant exosomes and resveratrol and preparation method thereof |
| CN113273694A (en) * | 2021-05-31 | 2021-08-20 | 东莞自然衡健康科技有限公司 | Weight management composition containing plant exosomes and preparation method thereof |
| CN113729211A (en) * | 2021-08-04 | 2021-12-03 | 北京斯利安健康科技有限公司 | Composition and preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 郑建仙主编: "《桂北药用植物资源现代研究》", 30 September 1999, 中国海洋大学出版社, pages: 509 - 511 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024025934A1 (en) * | 2022-07-29 | 2024-02-01 | Abbott Laboratories | Methods for promoting healthy catch-up growth |
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