CN115461073A - 用于增强树突细胞和T细胞激活以及用于诱导Th-1免疫应答的体外方法和组合物 - Google Patents

用于增强树突细胞和T细胞激活以及用于诱导Th-1免疫应答的体外方法和组合物 Download PDF

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CN115461073A
CN115461073A CN202080084824.5A CN202080084824A CN115461073A CN 115461073 A CN115461073 A CN 115461073A CN 202080084824 A CN202080084824 A CN 202080084824A CN 115461073 A CN115461073 A CN 115461073A
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antigen
cells
dendritic cells
agonist
palmitoyl
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Chinese (zh)
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M·L·博施
L·F·鲍尔斯
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Northwest Biotherapeutics LLC
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Northwest Biotherapeutics LLC
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CN202080084824.5A 2019-10-07 2020-10-07 用于增强树突细胞和T细胞激活以及用于诱导Th-1免疫应答的体外方法和组合物 Pending CN115461073A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962912005P 2019-10-07 2019-10-07
US62/912,005 2019-10-07
PCT/US2020/054621 WO2021071977A1 (en) 2019-10-07 2020-10-07 In vitro methods and compositions for enhancing the activation of dendritic cells and t cells, and for inducing a th-1 immune response

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CN115461073A true CN115461073A (zh) 2022-12-09

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CN202080084824.5A Pending CN115461073A (zh) 2019-10-07 2020-10-07 用于增强树突细胞和T细胞激活以及用于诱导Th-1免疫应答的体外方法和组合物

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US (1) US20240122975A1 (https=)
EP (1) EP4041298A4 (https=)
JP (1) JP2022552200A (https=)
KR (1) KR20220098351A (https=)
CN (1) CN115461073A (https=)
AU (1) AU2020363707A1 (https=)
BR (1) BR112022006743A2 (https=)
CA (1) CA3157004A1 (https=)
IL (1) IL292009A (https=)
MX (1) MX2022004186A (https=)
WO (1) WO2021071977A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180318414A1 (en) 2015-01-12 2018-11-08 Children's Medical Center Corporation Pro-Inflammatory and Adjuvant Functions of Toll-Like Receptor 4 Antagonists
JP7753205B2 (ja) * 2019-11-18 2025-10-14 ザ・チルドレンズ・メデイカル・センター・コーポレーシヨン 超活性樹状細胞は養子細胞移植に基づく持続性抗腫瘍免疫を可能にする
WO2024151124A1 (ko) * 2023-01-12 2024-07-18 주식회사 이뮤노맥스 항암능이 우수한 기억 t 세포 유래 면역세포치료제의 제조방법

Citations (3)

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CN102973928A (zh) * 2001-09-06 2013-03-20 西北生物治疗药物公司 引发单核树突细胞和t细胞th-1应答的组合物和方法
WO2016115097A2 (en) * 2015-01-12 2016-07-21 Children's Medical Center Corporation Pro-inflammatory and adjuvant functions of toll-like receptor 4 antagonists
CN108291204A (zh) * 2015-09-15 2018-07-17 西北生物治疗药物公司 涉及用于患有晚期癌症的受试者的经活化树突状细胞组合物和免疫治疗处理的方法

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CN107849537A (zh) * 2015-06-30 2018-03-27 西北生物治疗药物公司 诱发改善的或增加的抗肿瘤免疫应答的经最佳活化的树突细胞

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102973928A (zh) * 2001-09-06 2013-03-20 西北生物治疗药物公司 引发单核树突细胞和t细胞th-1应答的组合物和方法
WO2016115097A2 (en) * 2015-01-12 2016-07-21 Children's Medical Center Corporation Pro-inflammatory and adjuvant functions of toll-like receptor 4 antagonists
CN108291204A (zh) * 2015-09-15 2018-07-17 西北生物治疗药物公司 涉及用于患有晚期癌症的受试者的经活化树突状细胞组合物和免疫治疗处理的方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZANONI, IVAN等: "An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells", 《SCIENCE》, vol. 352, no. 6290, 3 June 2016 (2016-06-03), pages 1232 - 1236 *

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WO2021071977A1 (en) 2021-04-15
EP4041298A4 (en) 2024-07-24
EP4041298A1 (en) 2022-08-17
CA3157004A1 (en) 2021-04-15
BR112022006743A2 (pt) 2022-08-30
MX2022004186A (es) 2022-07-19
AU2020363707A1 (en) 2022-04-28
IL292009A (en) 2022-06-01
KR20220098351A (ko) 2022-07-12
AU2020363707A8 (en) 2022-05-05
US20240122975A1 (en) 2024-04-18
JP2022552200A (ja) 2022-12-15

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