CN115399749A - Fixing device and magnetic resonance inspection device of rodent experimental animals - Google Patents
Fixing device and magnetic resonance inspection device of rodent experimental animals Download PDFInfo
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- CN115399749A CN115399749A CN202210876855.5A CN202210876855A CN115399749A CN 115399749 A CN115399749 A CN 115399749A CN 202210876855 A CN202210876855 A CN 202210876855A CN 115399749 A CN115399749 A CN 115399749A
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- 241000283984 Rodentia Species 0.000 title claims abstract description 89
- 238000010171 animal model Methods 0.000 title claims abstract description 81
- 238000007689 inspection Methods 0.000 title abstract description 10
- 230000000149 penetrating effect Effects 0.000 claims description 13
- 238000002474 experimental method Methods 0.000 claims description 5
- 238000004891 communication Methods 0.000 claims description 2
- 238000011160 research Methods 0.000 abstract description 6
- 238000002604 ultrasonography Methods 0.000 description 10
- 238000005516 engineering process Methods 0.000 description 8
- 210000004556 brain Anatomy 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 238000005481 NMR spectroscopy Methods 0.000 description 4
- 210000003625 skull Anatomy 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 210000003169 central nervous system Anatomy 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000004007 neuromodulation Effects 0.000 description 2
- 230000000452 restraining effect Effects 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010033546 Pallor Diseases 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- 238000002679 ablation Methods 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 238000007428 craniotomy Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 210000001951 dura mater Anatomy 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000007917 intracranial administration Methods 0.000 description 1
- 230000005865 ionizing radiation Effects 0.000 description 1
- 238000002595 magnetic resonance imaging Methods 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000007674 radiofrequency ablation Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/70—Means for positioning the patient in relation to the detecting, measuring or recording means
- A61B5/702—Posture restraints
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/40—Animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/003—Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
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Abstract
The invention provides a fixing device for rodent experimental animals and a magnetic resonance inspection device, relates to the field of experimental inspection devices, and solves the problem that rodent experimental research supporting equipment which is lack of a magnetic wave knife is available in the market at present. The fixing device for rodent experimental animals comprises: an examination bed; the experimental device is fixed on the examination bed and is an open container; the base is fixed on the opening of the experimental device; the base is provided with a first connecting groove communicated with the opening of the experimental device; the supporting seat is fixed on the base, and the supporting seat is provided with a fixing device for fixing the head and the trunk of the rodent experimental animal. The scheme of the invention realizes the treatment research of experimental rodent in the field of magnetic wave knives.
Description
Technical Field
The invention relates to the field of experimental examination devices, in particular to a fixing device for rodent experimental animals and a magnetic resonance examination device.
Background
Ultrasound is a mechanical wave with good pointing property (Directivity), and the focusing of ultrasound can bring various biological effects, which is always one of the important directions for the development of clinical treatment technology, and is widely explored and researched in various clinical treatment scenes. In the prior art, the technology is applied to pallor ablation of PD patients, and the tremor of the patients is improved. However, due to the interference effect of the skull, dura mater and other natural brain barriers on ultrasonic conduction, the skull needs to be opened to establish an auditory window for early brain application focused ultrasound therapy; meanwhile, the intracranial scale-bar ratio and the staggered repeat-and-transverse organization structure are easy to cause the dissipation, the offset and the attenuation of the ultrasonic focus, which greatly limits the application of the focused ultrasound in the central nervous system. In recent years, the maturation of new generation MRgFUS technology has overcome the above problems, and its successful commercialization has marked the beginning of central nervous system focused ultrasound therapy towards substantial clinical applications. The new generation MRgFUS technology utilizes the magnetic resonance imaging technology to judge the ultrasonic beam, ablate, focus and position, monitor the target area in real time, and guide the phased array transducer to lead the ultrasonic to pass through the skull and focus on the target area, thus realizing accurate and reliable brain ultrasonic focusing. Compared with the classical radio frequency ablation technology, the deep brain stimulation technology and the like, the MRgFUS has the advantages of no craniotomy anesthesia, real-time adjustment and positioning, real-time treatment monitoring, real-time curative effect observation, repeated treatment, no ionizing radiation and the like. Non-implantable neuromodulation technologies represented by magnetic resonance Guided Focused Ultrasound (MRgFUS) are promising to become important breakthrough ports for non-invasive precise PD therapy. MRgFUS is commonly called as a magnetic wave knife, and mainly guides focused ultrasound through MR imaging to perform target multi-effect neuromodulation treatment, and the current MRgFUS has some defects and problems in the practice and research process, which all need further rodent experimental research to explore target point schemes and parameter settings for magnetic wave knife treatment. However, related rodent experimental study supporting equipment is lacking in the market at present, and the therapeutic study of the magnetic wave knife by utilizing experimental animals cannot be met.
Disclosure of Invention
The invention aims to provide a fixing device for rodent experimental animals and a magnetic resonance inspection device, so as to realize nuclear magnetic inspection by utilizing the rodent experimental animals.
In order to solve the technical problems, the technical scheme of the invention is as follows:
an embodiment of the present invention provides a fixing device for a rodent experimental animal, including:
an examination bed;
the experimental device is fixed on the examination bed and is an open container;
the base is fixed on the opening of the experimental device; the base is provided with a first connecting groove communicated with the opening of the experimental device;
the supporting seat is fixed on the base, and the supporting seat is provided with a fixing device for fixing the head and the trunk of the rodent experimental animal.
Optionally, the supporting seat includes:
place the first recess of rodent experimental animals, be provided with in the first recess and link up from top to bottom the second intercommunication groove of supporting seat, the second intercommunication groove with the first intercommunication groove intercommunication of base.
Optionally, the side wall of the first groove is provided with a head fixing device for fixing the head of the rodent experimental animal.
Optionally, the head fixation device comprises:
the first rotating shaft penetrates through a first through hole at a first end on a first side wall of the second communicating groove and is rotatably connected with the supporting seat;
the second rotating shaft penetrates through a second through hole at the first end on the second side wall of the second communicating groove and is rotatably connected with the supporting seat;
the first end of the fixing plate is connected with the first end of the supporting seat in a sliding mode, the second end of the fixing plate is located between the first rotating shaft and the second rotating shaft, and the second end of the fixing plate is provided with a round hole penetrating through the fixing plate;
the head of the rodent experimental animal is placed in the second communicating groove, is positioned below the second end part of the fixing plate and is fixed by the first rotating shaft, the second rotating shaft and the fixing plate.
Optionally, the second end of the fixing plate has a round hole penetrating through the fixing plate, and the teeth of the experimental rodent pass through the round hole, so that the head of the experimental rodent is fixed on the fixing plate.
Optionally, the first end of fixed plate can make a round trip to slide along the vertical direction of supporting seat, just still be provided with on the up end of fixed plate and link up from top to bottom the waist shape hole of fixed plate, waist shape hole passes through the screw will the fixed plate is fixed the first end of supporting seat.
Optionally, a second end of the first sidewall of the first groove has a third through hole;
a second end of the second side wall of the first groove is provided with a fourth through hole;
and the trunk of the experimental animal is fixed by a binding belt passing through the third through hole of the second end of the first side wall of the first groove and the fourth through hole of the second end of the second side wall.
Optionally, the base is provided with a plurality of threaded holes penetrating through the base, and the threaded holes are arranged on two sides of the first connecting groove.
Optionally, a plurality of limiting holes penetrating through the supporting seat are formed in two sides of the first end face of the supporting seat, and the supporting seat is fixed on the base by penetrating through the limiting holes and the threaded holes in the base through screws.
An embodiment of the present invention further provides a magnetic resonance examination apparatus for a rodent experimental animal, including: the fixing device of rodent experimental animals, magnetic resonance host computer and as described in any one above, rodent experimental animals's fixing device's experimental apparatus, base and supporting seat with the inspection cavity of magnetic resonance host computer corresponds the setting.
The scheme of the invention at least comprises the following beneficial effects:
the above-mentioned aspect of the present invention provides a fixing device for a rodent experimental animal, comprising: an examination bed; the experimental device is fixed on the examination bed and is an open container; the base is fixed on the opening of the experimental device; the base is provided with a first connecting groove communicated with the opening of the experimental device; the supporting seat is fixed on the base, and the supporting seat is provided with a fixing device for fixing the head and the trunk of the rodent experimental animal. Can realize the fixation of the experimental rodent in the nuclear magnetic examination, has convenient operation and reliable work, and realizes the treatment research of the experimental rodent in the field of the magnetic wave knife.
Drawings
Fig. 1 is a schematic view of the general structure of a magnetic resonance examination apparatus for a rodent experimental animal of the present invention;
FIG. 2 is a partial schematic view of the magnetic resonance examination apparatus for a rodent experimental animal according to the present invention;
FIG. 3 is a schematic structural view of a fixing device for a rodent experimental animal according to the present invention;
FIG. 4 is a schematic view of a rodent fixing structure of the rodent experimental animal fixing device of the invention;
FIG. 5 is a schematic structural view of the experimental device of the rodent experimental animal fixing device of the invention;
wherein, 1, examining the bed; 100. experimental rodent animals; 2. an experimental device; 3. a base; 31. a first connecting groove; 32. a threaded hole; 4. a supporting seat; 40. a first groove; 41. a second communicating groove; 42. a first side wall; 43. a second side wall; 44. a third through hole; 45. a fourth via hole; 46. a limiting hole; 47. a first support plate; 48. a second support plate; 49. a threaded hole; 5. a fixing plate; 50. a circular hole; 61. a first rotating shaft; 62. a second rotating shaft; 7. a binding belt.
Detailed Description
Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be embodied in various forms and should not be limited by the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.
As shown in fig. 1, an embodiment of the present invention provides a rodent experimental animal fixing device, including:
an examination couch 1;
the experimental device 2 is fixed on the examining table 1, and the experimental device 2 is an open container;
the base 3 is fixed on the opening of the experimental device 2; a first connecting groove 31 communicated with the opening of the experimental device 2 is formed in the base 3;
the supporting seat 4, the supporting seat 4 is fixed on the base 3, be provided with the fixing device of the head and the truck of fixed rodent experimental animals on the supporting seat 4.
As shown in fig. 5, in the present embodiment, the experimental apparatus 2 is provided with a phased array ultrasound focusing device for focusing ultrasound, specifically, a phased array ultrasound unit is placed at the bottom of an open container, water is stored in the open container, the brain of the rodent experimental animal 100 is contacted with the water in the open container through a first connecting groove 31, and two observation grooves are further provided on two sides of the first connecting groove 31 of the base 3 for fixing the water level in the open container after the experimental animal is observed.
As shown in fig. 2, fig. 3 and fig. 4, in an alternative embodiment of the present invention, the supporting seat 4 includes:
the first groove 40 for placing the rodent experimental animal 100 is provided with a second communicating groove 41 which vertically penetrates through the supporting seat 4, and the second communicating groove 41 is communicated with the first communicating groove 31 of the base 3.
The side wall of the first groove 40 is provided with a head fixing device for fixing the head of the rodent experimental animal 100, and the head fixing device comprises:
a first rotating shaft 61, wherein the first rotating shaft 61 passes through a first through hole at a first end of the first side wall 42 of the second communicating groove 41 and is rotatably connected with the supporting seat 4;
a second rotating shaft 62, wherein the second rotating shaft 62 passes through the second through hole at the first end of the second side wall 43 of the second communicating groove 41 and is rotatably connected with the supporting seat 4;
a fixed plate 5, a first end of the fixed plate 5 is slidably connected to a first end of the support base 4, a second end of the fixed plate 5 is located between the first rotating shaft 61 and the second rotating shaft 62, and the second end of the fixed plate 5 has a circular hole 50 penetrating through the fixed plate 5;
the head of the rodent experimental animal 100 is placed in the second communication groove 41, is positioned below the second end portion of the fixing plate 5, and is fixed by the first rotating shaft 61, the second rotating shaft 62 and the fixing plate 5.
The second end of the fixing plate 5 has a circular hole 50 penetrating through the fixing plate 5, and the teeth of the experimental rodent 100 pass through the circular hole 50, so that the head of the experimental rodent 100 is fixed on the fixing plate 5.
The first end of fixed plate 5 can make a round trip to slide along the vertical direction of supporting seat 4, just still be provided with on the up end of fixed plate 5 and link up from top to bottom the waist shape hole of fixed plate 5, the waist shape hole will through the screw fixed plate 5 is in the first end of supporting seat 4.
In this embodiment, the rodent experimental animal 100 is placed in the first groove 40 with the head of the rodent experimental animal facing upward, the head of the rodent experimental animal is positioned above the second communicating groove 41 and is in contact with the water in the experimental device 2, then the teeth of the rodent experimental animal 100 are passed through the circular hole 50, then the fixing plate 5 is slid, the nose-to-mouth portion of the rodent experimental animal 100 is pressed on the first supporting plate 47 at the first end of the first groove 40, the ear of the rodent experimental animal 100 is positioned at the middle position between the first rotating shaft 61 and the second rotating shaft 62, then the fixing plate 5 is fixed at the first end of the supporting seat 4 by passing screws through the waist-shaped holes on the fixing plate 5, and the ear of the rodent experimental animal 100 is fixed by rotating the first rotating shaft 61 and the second rotating shaft 62.
The first and second rotating shafts 61 and 62 for fixing the ear of the rodent experimental animal 100 in this embodiment are not limited, as long as the ear of the rodent experimental animal 100 is fixed, and the first and second rotating shafts 61 and 62 in this embodiment may be rotating shafts designed to have an external thread shape, and simultaneously, the first and second through holes are internally and respectively provided with internal threads corresponding to the first and second rotating shafts 61 and 62, the first and second rotating shafts 61 and 62 are fixed by internal and external thread structures, or the first and second rotating shafts 61 and 62 are further fixed by a screw hole 49 drilled directly above the first and second through holes and communicated with the first and second through holes, and the first and second rotating shafts 61 and 62 are further fixed by a matching screw, so that the ear of the rodent experimental animal 100 is fixed by the first and second rotating shafts 61 and 62.
In an alternative embodiment of the present invention, the second end of the first sidewall 42 of the first groove 40 has a third through hole 44; the second end of the second sidewall 43 of the first groove 40 has a fourth through hole 45;
the trunk of the experimental animal 100 is fixed to the second support plate 48 at the second end of the first recess 40 by passing the restraining band 7 through the third through hole 44 at the second end of the first sidewall 42 of the first recess 40 and the fourth through hole 45 at the second end of the second sidewall 43.
In an alternative embodiment of the present invention, as shown in fig. 3, a plurality of threaded holes 32 are formed in the base 3, and the threaded holes 32 are arranged on two sides of the first connecting groove 31.
The two sides of the first end face of the supporting seat 4 are provided with a plurality of limiting holes 46 penetrating through the supporting seat 4, and the supporting seat 4 is fixed on the base 3 by screws penetrating through the limiting holes 46 and the threaded holes 32 in the base 3.
In this embodiment, the design of the threaded hole 32 is used for conveniently adjusting the position of the support seat 4 on the base 3, and after the support seat 4 is moved to a proper position along the threaded holes 32 on the two sides of the first connecting groove 31, the support seat 4 is fixed on the base 3 by passing through the limiting hole 46 and the threaded hole 32 on the base 3 through screws.
As shown in fig. 1, another embodiment of the present invention provides a magnetic resonance examination apparatus for a rodent experimental animal, including: the fixing device for the rodent experimental animal comprises a magnetic resonance host 6 and the fixing device for the rodent experimental animal as described in the above embodiments, wherein the experimental device 2, the base 3 and the supporting seat 4 of the fixing device for the rodent experimental animal are arranged corresponding to the inspection cavity of the magnetic resonance host.
In this embodiment, the magnetic resonance host 6 is used for performing an experiment operation on the fixed experimental animal 100.
The specific working flow of the fixing device for rodent experimental animals in the embodiment is as follows: first, an anesthetized rodent experimental animal 100 is placed in the first groove 40 with the limbs upward, the trunk of the rodent experimental animal 100 is positioned on the second support plate 48 at the second end of the first groove 40, the head of the rodent experimental animal is positioned above the second communicating groove 41 and is contacted with water in the experimental device 2, then the teeth of the rodent experimental animal 100 are passed through the round hole 50, then the fixing plate 5 is slid, the nose to mouth part of the rodent experimental animal 100 is pressed on the first support plate 47 at the first end of the first groove 40, the ear part of the rodent experimental animal 100 is positioned at the middle position of the first rotating shaft 61 and the second rotating shaft 62, then the fixing plate 5 is fixed at the first end of the support seat 4 through the waist-shaped hole on the fixing plate 5 by a screw, the ear part of the rodent experimental animal 100 is fixed by rotating the first rotating shaft 61 and the second rotating shaft 62, and then the ear part of the rodent experimental animal 100 is fixed on the fourth support plate 48 at the second end of the trunk hole 45 of the rodent experimental animal 40 by the restraining belt 7 passing through the first end 42 and the second end of the first side wall 42 of the first groove 40. Promote finally the inspection bed 1 sends into the rodent experimental animal 100 that has fixed in the cavity of magnetic resonance host computer 6, through the phased array ultrasonic focusing equipment of the focus supersound among the experimental apparatus 2 with the experimental operation is carried out to rodent experimental animal 100 to magnetic resonance host computer 6, specifically, utilizes MR (nuclear magnetic resonance) body coil, carries out focus supersound intervention experiment under the MR guide, passes through after the experiment the inspection bed 1 pulls out rodent experimental animal 100 magnetic resonance host computer 6 takes off rodent experimental animal 100.
The fixing device for the rodent experimental animals solves the problem that the rodent experimental research supporting equipment which is lack of the magnetic wave knife is available in the market at present, and has the advantages of simple structure, convenience in operation and reliability in work.
While the foregoing is directed to the preferred embodiment of the present invention, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the invention as defined in the appended claims.
Claims (10)
1. A rodent experimental animal fixture, comprising:
an examination couch (1);
the experiment device (2) is fixed on the examination bed (1), and the experiment device (2) is an open container;
the base (3), the said base (3) is fixed on opening of the said experimental apparatus (2); a first connecting groove (31) communicated with the opening of the experimental device (2) is formed in the base (3);
the supporting seat (4), the supporting seat (4) is fixed on the base (3), be provided with the fixing device of the head and the truck of fixed rodent experimental animals on supporting seat (4).
2. The rodent experimental animal fixing device according to claim 1, characterized in that the support seat (4) comprises:
the first groove (40) for placing the rodent experimental animal (100), a second communicating groove (41) which penetrates through the supporting seat (4) from top to bottom is formed in the first groove (40), and the second communicating groove (41) is communicated with the first communicating groove (31) of the base (3).
3. The rodent experimental animal fixing device according to claim 2, characterized in that the side wall of the first groove (40) is provided with a head fixing device for fixing the head of the rodent experimental animal (100).
4. The rodent experimental animal fixture of claim 3, wherein the head fixture comprises:
the first rotating shaft (61), the first rotating shaft (61) penetrates through a first through hole at a first end on a first side wall (42) of the second communicating groove (41) and is rotatably connected with the supporting seat (4);
the second rotating shaft (62) penetrates through a second through hole at the first end of the second side wall (43) of the second communicating groove (41) and is rotatably connected with the supporting seat (4);
a fixed plate (5), wherein a first end of the fixed plate (5) is slidably connected with a first end of the support seat (4), a second end of the fixed plate (5) is located between the first rotating shaft (61) and the second rotating shaft (62), and the second end of the fixed plate (5) is provided with a round hole (50) penetrating through the fixed plate (5);
the head of the rodent experimental animal (100) is placed in the second communication groove (41), is positioned below the second end part of the fixing plate (5), and is fixed by the first rotating shaft (61), the second rotating shaft (62) and the fixing plate (5).
5. The rodent experimental animal fixing device according to claim 3 or 4, characterized in that the second end of the fixing plate (5) is provided with a round hole (50) penetrating through the fixing plate (5), the teeth of the rodent experimental animal (100) pass through the round hole (50), and the head of the rodent experimental animal (100) is fixed on the fixing plate (5).
6. The rodent experimental animal fixing device according to claim 5, wherein the first end of the fixing plate (5) can slide back and forth along the vertical direction of the supporting seat (4), and a waist-shaped hole which penetrates through the fixing plate (5) up and down is further arranged on the upper end surface of the fixing plate (5), and the fixing plate (5) is fixed at the first end of the supporting seat (4) through a screw in the waist-shaped hole.
7. The rodent experimental animal fixing device of claim 4,
a second end of the first side wall (42) of the first groove (40) is provided with a third through hole (44);
a second end of the second side wall (43) of the first groove (40) is provided with a fourth through hole (45);
the trunk of the experimental animal (100) is fixed by a binding band (7) passing through a third through hole (44) of the second end of the first sidewall (42) and a fourth through hole (45) of the second end of the second sidewall (43) of the first groove (40).
8. The rodent experimental animal fixing device according to claim 1, characterized in that the base (3) is provided with a plurality of threaded holes (32) penetrating the base (3), the threaded holes (32) being arranged on both sides of the first connecting groove (31).
9. The rodent experimental animal fixing device according to claim 8, characterized in that a plurality of limiting holes (46) penetrating through the supporting seat (4) are arranged on two sides of the first end surface of the supporting seat (4), and the supporting seat (4) is fixed on the base (3) through the limiting holes (46) and the threaded holes (32) on the base (3) by screws.
10. A magnetic resonance examination apparatus for rodent laboratory animals, comprising: the rodent experimental animal fixing device of one of the claims 1 to 9 and the magnetic resonance main machine (6), wherein the experimental device (2), the base (3) and the supporting seat (4) of the rodent experimental animal fixing device are arranged corresponding to the examination cavity of the magnetic resonance main machine.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202210876855.5A CN115399749A (en) | 2022-07-25 | 2022-07-25 | Fixing device and magnetic resonance inspection device of rodent experimental animals |
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| CN202210876855.5A CN115399749A (en) | 2022-07-25 | 2022-07-25 | Fixing device and magnetic resonance inspection device of rodent experimental animals |
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| CN103919626A (en) * | 2014-04-22 | 2014-07-16 | 中国科学技术大学 | Small animal brain three-dimensional positioning system for magnetic resonance imaging scanning equipment |
| CN206103132U (en) * | 2016-07-19 | 2017-04-19 | 中国科学院深圳先进技术研究院 | High strength focus ultrasound therapy device of magnetic resonance guide |
| KR20180114465A (en) * | 2017-04-10 | 2018-10-18 | 경희대학교 산학협력단 | Fixing apparatus for small animals |
| CN211658411U (en) * | 2019-10-31 | 2020-10-13 | 上海市第一人民医院 | Transcranial focused ultrasound experimental equipment with magnetic resonance compatibility |
| CN211985787U (en) * | 2019-12-24 | 2020-11-24 | 浙江大学医学院附属第四医院 | Head fixing device suitable for rat to carry out magnetic resonance and CT examination |
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| CN114668381A (en) * | 2022-02-17 | 2022-06-28 | 中国科学院深圳先进技术研究院 | Marmoset monkey nuclear magnetic compatibility orientator |
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