CN115327149A

CN115327149A - Full-automatic immunity analyzer and analysis and detection method thereof

Info

Publication number: CN115327149A
Application number: CN202211232644.4A
Authority: CN
Inventors: 李石存; 何东陆; 黄欣; 陈文杰
Original assignee: Hunan Chaoji Testing Technology Co ltd
Current assignee: Hunan Chaoji Testing Technology Co ltd
Priority date: 2022-10-10
Filing date: 2022-10-10
Publication date: 2022-11-11
Anticipated expiration: 2042-10-10
Also published as: CN115327149B

Abstract

The invention discloses a full-automatic immunity analyzer and an analysis detection method thereof, wherein the analyzer comprises a sample transmission channel mechanism, a reagent tray mechanism, an incubation tray mechanism, a blending mechanism, an optical detection mechanism, a chip grabbing mechanism, a cup feeding mechanism and a cleaning mechanism, wherein the reagent tray mechanism, the incubation tray mechanism, the blending mechanism, the optical detection mechanism, the chip grabbing mechanism, the cup feeding mechanism and the cleaning mechanism are arranged at one side of the sample transmission channel mechanism; a second cup grabbing mechanism is arranged between the blending mechanism and the incubation disc mechanism; a sample arm is also arranged between the sample conveying channel mechanism and the incubation disc mechanism; a reagent arm is arranged between the reagent tray mechanism and the incubation tray mechanism, and a sample storage mechanism and a sample taking and placing mechanism are arranged at one end of the sample conveying channel mechanism; the sample is stored in the sample storage mechanism, and the sample taking and placing mechanism can automatically take the sample from the sample storage mechanism and send the sample to the sample conveying channel mechanism or recycle the sample taken by the sample conveying channel mechanism into the sample storage mechanism.

Description

Full-automatic immunity analyzer and analysis and detection method thereof

Technical Field

The invention relates to the technical field of medical examination, in particular to a full-automatic immunoassay analyzer and an analysis and detection method thereof.

Background

Since the first automated chemical analysis instrument was manufactured to date, over half a century of development, fully automated immunoassays have matured in technology. The existing full-automatic immunoassay analyzer has the following characteristics: 1. a multi-degree-of-freedom mechanical arm is adopted to coordinate the actions among the modules; 2. the instrument has strong flexibility and can meet various analysis requirements; 3. the test speed is high, and the continuous running time without human intervention is long; 4. the detection technology adopts the combination of various technologies and the full automation of the processing, so that the detection result is more accurate and the precision is higher. The full-automatic immunity analyzer can realize the steps of taking a reaction cup, adding a standard book, adding a reaction liquid, shaking uniformly, promoting reaction, measuring, performing operational analysis, cleaning and the like in the experimental test process, replaces manual operation, not only saves labor cost, but also stops human errors more importantly and ensures the accuracy of data. The full-automatic immunoassay analyzer has the advantages of rapidness, high efficiency, high precision, repeated consistency and the like, is widely applied to the fields of processing, production, testing, life assistance and the like, and inevitably becomes a trend in the field of medical detection.

The detection efficiency is a key technical index of the full-automatic immunoassay analyzer, and the analyzer with high detection efficiency greatly helps people in actual work under the condition of huge detection amount. In order to improve the detection efficiency, the continuous optimization of the mechanical automation technology of the full-automatic immunoassay analyzer is an important approach.

In a fully automatic immunoassay analyzer, a sample is used as a test object, which is the basis of an analysis detection work. The efficiency of the analysis and detection work is directly affected by the indexes such as the sample loading capacity and the sample conveying speed, and therefore, the design of the aspects such as storage, taking and conveying, and the like of the samples is very important in the fully automatic immunoassay analyzer. With the progress of detection technology, the application of the full-automatic immunoassay analyzer is wider and wider, and the market puts higher requirements on the access quantity and the access speed of samples.

The following three comparative patent documents were retrieved:

1. the Chinese patent application with the patent application publication number of CN113504380A and the application publication number of 2021, 10 and 15 discloses a full-automatic chemiluminescent immunoassay analyzer, which comprises a transmission track module, a reaction cup loading module, a sample filling module, a reagent filling module, a reaction disc module, a magnetic separation disc module and a detection module, wherein after a sample needle is rotated to a sampling position of the transmission track module by the sample filling module, the sample needle is inserted into a liquid level for sampling, and after sampling is finished, the sample needle is lifted and rotated to the sampling position of the reaction disc module for sampling; and after the reaction is finished, the reaction disk module transfers the reaction cup to the magnetic separation module, adsorbs the components participating in the reaction on the wall of the reaction cup, and extracts the components not participating in the reaction, or transfers the reaction cup to the detection module by the reaction disk module, and the sample is analyzed and detected.

2. Chinese utility model patent with publication number CN208937504U and publication date of 2019, 6 months and 4 days discloses a full-automatic chemiluminescence immunoassay analyzer, which comprises: a sample conveying device, a reaction cup conveying device, a reagent conveying device, a reaction device and an optical detection device; the reaction device is used for placing the reaction cups conveyed by the reaction cup conveying device and receiving the samples conveyed by the sample conveying device and the reagents conveyed by the reagent conveying device into the reaction cups; the reaction device comprises a reaction disc, an incubation component and a shaking mechanism; the reaction disc is provided with at least two circles of reaction cup rails, and a reaction cup accommodating cavity is arranged at the same position of each reaction cup rail; the incubation assembly is arranged along the circumferential direction of the reaction disc; the shaking mechanism is fixedly connected to the reaction cup accommodating cavity at any position, and after the reaction cup rotates to the reaction cup accommodating cavity, the shaking mechanism shakes the reaction cup uniformly; the optical detection device is used for receiving and detecting the test solution reacted by the reaction device.

3. The Chinese utility model patent with the publication number of CN 217180948U and the publication date of 2022, 8 months and 12 days discloses a full-automatic chemiluminescence immunoassay analyzer with high compactness, which comprises an equipment frame, wherein a sample system, a reagent system, a washing module, an incubation module, a detection module and a filling system are arranged in the equipment frame, the reagent system is of a circular structure, and the sample system concentric ring surrounds the circumferential outer side of the reagent system; the detection module comprises a circular tray which is rotatably arranged and a light-emitting detection assembly positioned outside the circular tray, and detection gaps for mounting reaction cups are distributed on the circumferential edge of the circular tray; the incubation module is integrally arranged in the central area of the circular tray; a transfer module is arranged between the washing module and the detection module and used for placing a reaction cup, the washing module, the transfer module and the detection module are positioned on the same straight line, and a mechanical clamping arm is transversely arranged above the transfer module; the filling system is located between the sample system and the transfer module and comprises a stand column and a cantilever arranged at the top end of the stand column, a filling needle is fixedly installed on the lower portion of the far end of the cantilever, and the filling needle rotates along the axis of the stand column along with the cantilever and slides along the axis direction of the stand column.

In the first patent document, there is no disclosure of how the sample to be sampled is placed on the transfer rail module and how the sampled sample is taken from the transfer rail module, which would inevitably affect the detection efficiency if done manually.

In both the second and third patent documents, the samples are arranged in a ring shape, which occupies a relatively large space; and the sample is taken and sent manually, and automation is not realized, so that the detection efficiency is inevitably influenced.

In conclusion, how to design a full-automatic immunoassay analyzer and an analysis and detection method thereof, which can improve the detection efficiency after the optimization design of each component mechanism, and adapt to the complex and huge detection task requirements is a technical problem which is urgently needed to be solved.

Disclosure of Invention

The invention aims to solve the technical problem of the prior art and provides a full-automatic immunoassay analyzer and an analysis and detection method thereof.

In order to solve the technical problems, the technical scheme adopted by the invention is as follows: a full-automatic immunity analyzer comprises a sample conveying channel mechanism, a reagent tray mechanism, an incubation tray mechanism, a blending mechanism, an optical detection mechanism, a chip grabbing mechanism, a cup feeding mechanism and a cleaning mechanism, wherein the reagent tray mechanism, the incubation tray mechanism, the blending mechanism, the optical detection mechanism, the chip grabbing mechanism, the cup feeding mechanism and the cleaning mechanism are arranged at one side of the sample conveying channel mechanism; a second cup grabbing mechanism is arranged between the blending mechanism and the incubation disc mechanism; a sample arm is also arranged between the sample conveying channel mechanism 1 and the incubation disc mechanism; a reagent arm is arranged between the reagent tray mechanism and the incubation tray mechanism, and a sample storage mechanism and a sample taking and placing mechanism are arranged at one end of the sample conveying channel mechanism; the sample is stored in the sample storage mechanism, and the sample taking and placing mechanism can automatically take the sample from the sample storage mechanism and send the sample to the sample conveying channel mechanism or recover the sample after taking the sample from the sample conveying channel mechanism to the sample storage mechanism.

Preferably, the sample storage mechanism includes a storage table and a sample tube carrier placed on the storage table, and a plurality of sample tube racks are placed in the sample tube carrier.

Preferably, the sample tube basket comprises a handle and a basket frame, the basket frame comprises a basket bottom plate and a basket enclosure arranged on the periphery of the basket bottom plate, three sides of the basket frame are provided with the basket enclosure, and one side of the basket enclosure is provided with an opening of the basket enclosure; the basket bottom plate is provided with a plurality of basket partition plates which are arranged in parallel, the basket partition plates are arranged towards the opening direction of the basket enclosure, the internal space of the basket frame is divided into a plurality of strip-shaped groove-shaped spaces by the plurality of basket partition plates, and each groove-shaped space is provided with a sample pipe frame; and a basket sliding groove is arranged in each groove-shaped space and positioned on the basket bottom plate.

Preferably, the sample taking and placing mechanism comprises an ejecting component and a taking and placing component, and the ejecting component is arranged at the bottom of the table top of the storage table; the pick-and-place component is arranged at a position between the table top and the sample conveying channel mechanism.

Preferably, a plurality of stations are arranged on the table board, a plurality of table board through grooves are formed in each station, the sample tube lifting basket is placed on the station on the table board, and each table board through groove corresponds to one sample tube frame;

the pushing component comprises a pushing component base body and a pushing block connected to the pushing component base body in a sliding mode, and the pushing component base body is connected to the bottom plate of the storage table in a sliding mode; the bottom plate is also provided with a first power mechanism for driving the pushing component substrate to move, and the pushing component substrate can move back and forth under the driving of the first power mechanism; the pushing part base body is also provided with a second power mechanism for driving the pushing block to move, and the pushing block can move back and forth under the driving of the second power mechanism; the pushing block is also provided with a telescopic push rod which can extend out of or retract into the pushing block, and the pushing block is also provided with a driving motor III for controlling the telescopic push rod to extend out of or retract into;

the taking and placing component comprises a taking and placing component base body, the taking and placing component base body is connected to the bottom plate in a sliding mode, a third power mechanism is further arranged on the bottom plate, and the taking and placing component base body can move back and forth under the driving of the third power mechanism; a conveying channel for conveying the sample pipe frame is further arranged on the taking and placing component base body, and a conveying belt for conveying the sample pipe frame is arranged at the bottom of the conveying channel;

after the sample tube lifting basket is placed on a station on the table board, the pushing block of the pushing component extends out to penetrate through the through groove of the table board and the lifting basket sliding groove and then contacts with the sample tube rack to push the sample tube rack to move, then the pushing block is utilized to push the sample tube rack to move and the conveying belt of the conveying channel is utilized to drive the sample tube rack to move, and the sample tube rack is completely moved to the conveying belt of the conveying channel.

Preferably, the sample transfer passage mechanism includes a passage frame and a plurality of transfer passages provided on the passage frame;

the sample storage mechanism is positioned at one end of the sample conveying channel mechanism, and the other end of the sample conveying channel mechanism is also provided with a channel switching component, and a sample tube rack on any one conveying channel can be switched to the other conveying channel through the channel switching component.

Preferably, the passageway switches the part and includes the part base plate and set up passageway on the part base plate switches synchronous belt drive mechanism sliding connection has the slide arm on the part base plate, and the one end and the passageway of slide arm switch synchronous belt drive mechanism and are connected to under the drive that synchronous belt drive mechanism was switched to the passageway, ability round trip movement still is provided with U type draw-in groove body on the other end of slide arm, U type draw-in groove body level sets up, and its U type opening direction is towards transfer passage.

Preferably, the reagent tray mechanism comprises a shell, a rotating disc and a plurality of reagent boxes, the rotating disc is rotatably arranged in the shell, the reagent boxes are arranged on the rotating disc, the rotating disc is connected with a driving motor five in a matching mode, each reagent box comprises a box body, a plurality of mutually independent reagent accommodating cavities I are arranged in the box body, a reagent pipe is further rotatably connected to one end of the box body, and a reagent accommodating cavity II is arranged in the reagent pipe; the reagent tube is characterized in that a plurality of first transmission mechanisms are arranged on the rotary disc, the bottom of each reagent tube is connected with one first transmission mechanism, a second transmission mechanism and a sixth driving motor are further arranged inside the shell, the second transmission mechanism is in transmission connection with the first transmission mechanism in a matched mode, and the reagent tubes are in transmission connection with the sixth driving motor in a matched mode through the first transmission mechanism and the second transmission mechanism.

Preferably, drive mechanism one includes carousel, lower gear and connects go up the connecting axle of carousel and lower gear, go up the relative both sides position that carousel and lower gear are located the carousel respectively, the connecting axle passes the carousel just the one end of connecting axle is connected with last carousel, the other one end and the lower gear connection of connecting axle.

Preferably, the second transmission mechanism comprises a bidirectional gear ring, a gear ring bearing and a second driving gear, the gear ring bearing is arranged in the shell, an outer ring of the gear ring bearing is fixedly connected to the inner bottom of the shell, an inner ring of the gear ring bearing is connected with the bidirectional gear ring, so that the bidirectional gear ring is rotatably connected to the inner bottom of the shell, a second driving motor is further arranged in the shell, and the second driving gear is arranged on an output shaft of the second driving motor; and the second driving gear is in meshing transmission with the inner ring gear of the bidirectional gear ring, and the lower gear of each first transmission mechanism is in meshing transmission with the outer ring gear of the bidirectional gear ring, so that the second transmission mechanism is in matched transmission connection with the first transmission mechanism.

Preferably, the shell comprises a shell body and a shell cover arranged at an opening at the top end of the shell body; the top of each reagent containing cavity I is provided with an opening I, a reagent containing cavity II is arranged inside the reagent pipe, and the top of the reagent containing cavity II is also provided with an opening II; the cover is provided with through holes for the reagent needles to suck reagents conveniently, and the number of the through holes is consistent with the number of the first openings on one reagent kit and the second openings of the reagent tubes.

Preferably, every kit is the arc setting and a plurality of openings one and the opening two of reagent pipe on every kit also are the arc and arrange, and a plurality of curved kits set gradually on the reagent dish along the circumference of reagent dish, and is corresponding, and be a plurality of on the cap the through-hole also is the arc and arranges.

The invention also discloses an analysis and detection method of the full-automatic immunity analyzer, which comprises the following steps:

1) The first cup grabbing mechanism transfers the reaction cup from the cup feeding mechanism to the incubation disc mechanism;

2) The sample to be measured is placed on the sample storage mechanism, the sample taking and placing mechanism takes the sample from the sample storage mechanism to the sample taking and placing mechanism, the sample taking and placing mechanism takes the sample to the sample conveying channel mechanism, the sample is conveyed to a sampling position through the sample conveying channel mechanism, and the sample arm adds the sample to a reaction cup in the incubation disc mechanism;

3) The reagent arm sucks reagent from the reagent tray mechanism and adds the reagent into the reaction cup;

4) Transferring the reaction cup to a mixing mechanism by a cup grabbing mechanism II and mixing uniformly;

5) Transferring the uniformly mixed reaction cups to an incubation disc mechanism for incubation by a cup grabbing mechanism II;

6) Repeating the steps 3) to 5) for multiple times, and transferring the reaction cup to a cleaning mechanism from a cup grabbing mechanism for cleaning;

7) The washed reaction cup is transferred back to the incubation disc by the first cup grabbing mechanism, and then a luminescent substrate reagent is added by the reagent arm;

8) The chip grabbing mechanism is used for taking and placing the chip into the optical detection mechanism, the sample arm is used for sucking the sample to be detected from the reaction cup and adding the sample to be detected into the chip, and the optical detection mechanism is used for detecting the sample.

Preferably, the sample storage mechanism comprises a storage table and a sample tube carrier placed on the storage table, and a plurality of sample tube carriers are placed in the sample tube carrier; the sample tube lifting basket comprises a lifting handle and a basket frame, the basket frame comprises a lifting basket bottom plate and a lifting basket enclosure arranged on the periphery of the lifting basket bottom plate, three surfaces of the basket frame are provided with the lifting basket enclosure, and one surface of the basket frame is provided with an opening of the lifting basket enclosure; the basket bottom plate is provided with a plurality of basket partition plates which are arranged in parallel, the basket partition plates are arranged towards the opening direction of the basket enclosure, the internal space of the basket frame is divided into a plurality of strip-shaped groove-shaped spaces by the plurality of basket partition plates, and each groove-shaped space is provided with a sample pipe frame; a basket sliding groove is arranged in each groove-shaped space and positioned on the basket bottom plate; the sample taking and placing mechanism comprises a pushing component and a taking and placing component, and the pushing component is arranged at the bottom of the table top of the storage table; the taking and placing component is arranged between the table top and the sample conveying channel mechanism; a plurality of stations are arranged on the table board, a plurality of table board through grooves are formed in each station, the sample tube lifting basket is placed on the station on the table board, and each table board through groove corresponds to one sample tube frame; the pushing component comprises a pushing component base body and a pushing block connected to the pushing component base body in a sliding mode, and the pushing component base body is connected to the bottom plate of the storage table in a sliding mode; the bottom plate is also provided with a first power mechanism for driving the pushing component substrate to move, and the pushing component substrate can move back and forth under the driving of the first power mechanism; the pushing part base body is also provided with a second power mechanism for driving the pushing block to move, and the pushing block can move back and forth under the driving of the second power mechanism; the pushing block is also provided with a telescopic push rod which can extend out of or retract into the pushing block, and the pushing block is also provided with a driving motor III for controlling the telescopic push rod to extend out of or retract into the pushing block; the taking and placing component comprises a taking and placing component base body, the taking and placing component base body is connected to the bottom plate in a sliding mode, a third power mechanism is further arranged on the bottom plate, and the taking and placing component base body can move back and forth under the driving of the third power mechanism; a conveying channel for conveying the sample pipe rack is further arranged on the taking and placing component base body, and a conveying belt for conveying the sample pipe rack is arranged at the bottom of the conveying channel;

the step 2) is that a plurality of sample tubes sampled from the object to be tested are loaded into sample tube racks by workers, then the sample tube racks are loaded into sample tube baskets, and then the sample tube baskets are placed on a station on the table top of the storage table;

the telescopic push rod of the pushing component is controlled to extend out, the telescopic push rod sequentially penetrates through a table-board through groove on the table board and a basket lifting chute of the sample tube basket and then is contacted with a sample tube rack, and the action of a power mechanism II of the pushing component is controlled, so that the sample tube rack is pushed out to a conveying belt of the picking and placing component by the telescopic push rod; when the sample pipe racks enter the conveying belt, the conveying belt of the taking and placing part is controlled to act, so that the sample pipe racks are conveyed to the conveying belt under the pushing action of the telescopic push rods and the driving action of the conveying belt;

and after the sample pipe support is conveyed to the conveying belt, the conveying belt is controlled to stop acting, the picking and placing part base body of the picking and placing part is controlled to move to the sample conveying channel mechanism, then the conveying belt is controlled to act again, the sample pipe support is conveyed to the sample arm sampling position under the driving of the conveying belt and the sample conveying channel mechanism, and the sample arm is used for sampling.

Preferably, the sample transfer passage mechanism includes a passage frame and a plurality of transfer passages provided on the passage frame; the plurality of transmission channels comprise a recovery channel, and the other transmission channels are feeding channels; the sample storage mechanism is positioned at one end of the sample conveying channel mechanism, and a channel switching part is also arranged at the other end of the sample conveying channel mechanism; the channel switching component comprises a component substrate and a channel switching synchronous belt transmission mechanism arranged on the component substrate, a sliding arm is connected on the component substrate in a sliding manner, one end of the sliding arm is connected with the channel switching synchronous belt transmission mechanism, so that the sliding arm can move back and forth under the driving of the channel switching synchronous belt transmission mechanism, a U-shaped clamping groove body is also arranged at the other end of the sliding arm, the U-shaped clamping groove body is horizontally arranged, and the U-shaped opening direction of the U-shaped clamping groove body faces to the conveying channel;

in the step 2), after the sample arm finishes sampling, the method also comprises a sample tube rack recovery step, wherein the sample tube rack recovery step is to control a feeding channel to move after the sample arm finishes sampling, the sample tube rack which finishes sampling is conveyed to a U-shaped clamping groove body of a channel switching part, then the feeding channel is controlled to stop moving, a sliding arm of the channel switching part is controlled to move again to drive the U-shaped clamping groove body and the sample tube rack which finishes sampling to move together to a recovery channel, the recovery channel is controlled again to move the sample tube rack which finishes sampling to a taking and placing part, and the taking and placing part is controlled again to completely move the sample tube rack which finishes sampling to a sample storage mechanism to complete the recovery step.

Preferably, the reagent tray mechanism comprises a shell, a rotating disc and a plurality of reagent boxes, the rotating disc is rotatably arranged in the shell, the reagent boxes are arranged on the rotating disc, the rotating disc is connected with a driving motor five in a matching mode, each reagent box comprises a box body, a plurality of mutually independent reagent accommodating cavities I are arranged in the box body, a reagent pipe is further rotatably connected to one end of the box body, and a reagent accommodating cavity II is arranged in the reagent pipe; the reagent tube comprises a shell, a plurality of reagent tubes, a plurality of transmission mechanisms I, a transmission mechanism II and a driving motor VI, wherein the transmission mechanisms I are arranged on a turntable, the bottom of each reagent tube is connected with one transmission mechanism I, the transmission mechanism II and the transmission mechanism I are matched and in transmission connection, and the reagent tubes are matched and connected with the driving motor VI through the transmission mechanism I and the transmission mechanism II; the first transmission mechanism comprises an upper rotary table, a lower gear and a connecting shaft for connecting the upper rotary table and the lower gear, the upper rotary table and the lower gear are respectively positioned at two opposite sides of the rotary table, the connecting shaft penetrates through the rotary table, one end of the connecting shaft is connected with the upper rotary table, and the other end of the connecting shaft is connected with the lower gear; the transmission mechanism II comprises a bidirectional gear ring, a gear ring bearing and a driving gear II, the gear ring bearing is arranged in the shell, an outer ring of the gear ring bearing is fixedly connected to the inner bottom of the shell, an inner ring of the gear ring bearing is connected with the bidirectional gear ring, so that the bidirectional gear ring is rotatably connected to the inner bottom of the shell, a driving motor VI is further arranged in the shell, and the driving gear II is arranged on an output shaft of the driving motor VI; the driving gear II is in meshed transmission with an inner ring gear of the bidirectional gear ring, and a lower gear of each transmission mechanism I is in meshed transmission with an outer ring gear of the bidirectional gear ring, so that the transmission mechanism II is in matched transmission connection with the transmission mechanism I;

before the reagent arm sucks the reagent from the reagent disk mechanism in the step 3), a driving motor V of a power mechanism IV is controlled to act so as to drive the rotary disk to rotate; at the moment, the driving motor VI does not act, and the turntable can drive a lower gear of a transmission mechanism I connected with the reagent tube to rotate along an outer ring gear of the bidirectional gear ring, so that the reagent tube automatically rotates;

when the rotary table rotates to the position for sucking the reagent, the driving motor five is controlled to stop, the rotary table stops rotating, at the moment, the driving motor six is controlled to act, so that the driving gear two, the bidirectional gear ring, the lower gear of the transmission mechanism one, the connecting shaft of the transmission mechanism one and the upper rotary table of the transmission mechanism one are sequentially driven to rotate, and finally the reagent tube is driven to rotate through the rotation of the upper rotary table of the transmission mechanism one.

The invention has the beneficial effects that: the invention is optimized by the automatic sampling method and mechanism in the full-automatic immunity analyzer, a large number of sample pipe frames can be stored, and the number of samples is increased; the sample pipe frame is quickly conveyed to a sampling position in the automatic detection system for sampling in a mode that the pushing component and the taking and placing component of the sample taking and placing mechanism are matched with the relay, so that the requirement of quickly inputting the sample pipe frame is met, the structure of a main body of the automatic detection system is simplified, and the automatic detection system is more compact. After the sample is taken, the sample pipe support can be rapidly recycled, and the detection efficiency is further improved. The sample tube rack is provided with a plurality of one-way conveying channels and is used for conveying different detection items. The sample pipe support can line up in one-way transfer passage, carries out the conveying in order, improves the conveying quantity and the transfer rate of sample pipe support, has saved the transfer time, has improved detection speed. The reagent disk mechanism is optimized, the reagent tube loaded with the reagent easy to deposit and accumulate is connected to rotate independently on the integrated reagent kit, the first transmission mechanism and the second transmission mechanism are matched, the reagent tube is connected with the second servo driving motor through the first transmission mechanism and the second transmission mechanism, and therefore the reagent needle absorbs the reagent. Through the specific structural design of the first transmission mechanism and the second transmission mechanism, the continuous rotation function of the reagent tube is further ensured. The rotating angle position of the rotating disc can be monitored and controlled in real time by arranging the induction disc and the sensor, so that the specific rotating position of the reagent kit on the rotating disc can be controlled. The reagent box is optimized, the reagent box and the openings on the reagent box are arranged in an arc shape, and the reagent boxes with a plurality of arc shapes are sequentially arranged on the reagent plate along the circumferential direction of the reagent plate, so that the movement track of the reagent needle coincides with the arc arrangement positions of the openings, the reagent needle can suck the reagent conveniently, the suction time is shortened, and the working efficiency is improved.

Drawings

FIG. 1 is a schematic top view of a fully automatic immunoassay analyzer according to an embodiment of the present invention;

FIG. 2 is a schematic perspective view of a fully automatic immunoassay analyzer according to an embodiment of the present invention;

FIG. 3 is a schematic perspective view of a full-automatic immunoassay analyzer according to an embodiment of the present invention;

FIG. 4 is a first schematic perspective view of a sample tube rack with sample tubes according to an embodiment of the present invention;

FIG. 5 is a schematic perspective view of a sample tube rack with sample tubes according to an embodiment of the present invention;

FIG. 6 is a schematic perspective view of a sample tube carrier according to an embodiment of the present invention;

FIG. 7 is a schematic perspective view of a sample pick and place mechanism according to an embodiment of the present invention;

FIG. 8 is an enlarged view of portion A of FIG. 2;

FIG. 9 is a schematic partial perspective view of the ejection assembly of FIG. 7;

FIG. 10 is a partial perspective view of the pick-and-place assembly of FIG. 7;

fig. 11 is a schematic top view of a portion of the sample storage mechanism, sample pick and place mechanism, and sample transport channel mechanism of fig. 1;

FIG. 12 is a schematic top view of a sample transport channel mechanism according to an embodiment of the present invention;

FIG. 13 is a schematic partial perspective view of a sample transport path mechanism at a path switching member according to an embodiment of the present invention;

fig. 14 is a schematic partial perspective view of a U-shaped card slot in a channel switching component according to an embodiment of the present invention;

FIG. 15 is a schematic view illustrating a first principle of a process of transporting a sample tube rack from a sample tube basket to a pick-and-place component of a sample pick-and-place mechanism by using the sample pick-and-place mechanism according to an embodiment of the present invention;

FIG. 16 is a schematic diagram illustrating a second principle of the process of transporting the sample tube rack from the sample tube basket to the pick-and-place component of the sample pick-and-place mechanism by the sample pick-and-place mechanism according to the embodiment of the present invention;

FIG. 17 is a schematic diagram showing the principle of the process of transporting the sample tube rack from the sample tube basket to the pick-and-place component of the sample pick-and-place mechanism by the sample pick-and-place mechanism in the embodiment of the present invention;

FIG. 18 is a first perspective view of a reagent disk mechanism according to an embodiment of the present invention;

FIG. 19 is a schematic axial cross-sectional structural view of a reagent disk mechanism in an embodiment of the present invention;

FIG. 20 is a partial axial cross-sectional structural schematic view at one side of FIG. 19;

FIG. 21 is a second schematic perspective view of a reagent disk mechanism according to an embodiment of the present invention;

FIG. 22 is a schematic perspective view of a turntable according to an embodiment of the present invention;

FIG. 23 is an axial cross-sectional structural view of FIG. 22;

FIG. 24 is a schematic perspective view of the reagent cartridge of the embodiment of the present invention after being mounted on the turntable;

FIG. 25 is a schematic perspective view of a kit according to an embodiment of the present invention;

FIG. 26 is a schematic axial sectional view of a cartridge according to an embodiment of the present invention;

FIG. 27 is a schematic view in partial axial cross-section of the reagent vessel of FIG. 26;

FIG. 28 is an enlarged view of the portion B of FIG. 23;

FIG. 29 is a schematic axial sectional perspective view of a reagent disk with a cover and a reagent cartridge removed according to an embodiment of the present invention;

FIG. 30 is an enlarged view of section E of FIG. 29;

FIG. 31 is an enlarged view of portion F of FIG. 29;

FIG. 32 is a schematic perspective view of a housing cover according to an embodiment of the present invention;

FIG. 33 is a schematic diagram showing a track route of a reagent needle sucking up a reagent in a reagent cartridge according to the prior art;

FIG. 34 is a schematic diagram showing the track route of the reagent needle when aspirating the reagent in the reagent cartridge in the embodiment of the present invention;

in the figure: 1. a sample conveying channel mechanism, 111 a channel frame, 112 a conveying channel, 1121 a preferential feeding channel, 1122 a common feeding channel, 1123 a recovery channel, 2 a reagent tray mechanism, 3 an incubation tray mechanism, 4 a blending mechanism, 5 an optical detection mechanism, 6 a chip grabbing mechanism, 7 a cup feeding mechanism, 8 a cleaning mechanism, 9 a cup grabbing mechanism I, 10 a cup grabbing mechanism II, 11 a sample arm, 12 a reagent arm, 13 a sample storage mechanism, 14 a sample taking mechanism, 15 a storage table, 151 a table top, 1511 a table top through groove, 152 a bulge, 153 a bottom plate, 16 a sample tube lifting basket, 161 a lifting handle, 162 a basket frame, 1621 a lifting basket bottom plate, 1622 a lifting basket enclosure, 17 a sample tube, 171 a tube position, 172 a tube position sensing piece, 18 a sample tube frame, 19 an identification code, 20 a fixing magnetic steel, 21 reinforcing ribs, 22 a lifting basket partition plate, 23, a groove space, 24, a basket sliding groove, 25, a basket magnet, 26, a pushing component, 261, a pushing component base body, 262, a pushing block, 263, a telescopic push rod, 27, a taking and placing component, 271, a taking and placing component base body, 272, a conveying channel, 28, a common station, 29, a priority station, 30, a first sliding rail and guide block mechanism, 31, a second sliding rail and guide block mechanism, 32, a first power mechanism, 321, a first driving motor, 322, a first driving belt, 33, a second power mechanism, 331, a second driving motor, 332, a second driving belt, 34, a third driving motor, 35, a first positioning plate, 36, a first positioning sensor, 37, a second positioning plate, 38, a second positioning sensor, 39, a third sliding rail and guide block mechanism, 40, a third power mechanism, 401, a third driving motor, 402, a third driving belt, 41, a synchronous belt transmission mechanism, 411, a fourth driving motor, 412, a conveying belt, 42. a third positioning plate 43, a third positioning sensor 44, a sample tube rack code reader 45, a sample tube code reader 46, a sample conveyor belt 47, a channel switching component 471, a component base plate 472, a sliding arm 473, a fourth transmission belt 474, a U-shaped clamping groove body 48, a fourth positioning sensor 49, a fourth positioning plate 50, a channel side baffle 51, a fourth sliding rail and guide block mechanism 52, a fourth sliding rail and guide block mechanism 53, a fifth positioning sensor 54, a fifth positioning plate 55, a shell 551, a shell body 5511, an outer shell 5512, an inner shell 552, a shell cover 56, a turntable 561, a turntable body 562, a turntable cylinder 57, a kit, a box 571, a 572, a tube body installation cavity 58, a heat insulation material 59, a spindle bearing seat 60, a spindle, 61, a main gear 62, a sensing disc, 621, a sensing groove, 63, a sensor, 631, a first sensor, 632, a second sensor, 64, a support leg, 65, a mounting clamping groove, 651, a clamping groove through hole, 66, a driving motor, 67, a reagent cavity I, 671, an opening I, 68, a reagent tube, 681, a reagent cavity II, 682, an opening II, 683, a tube body, 684, a flange, 685, a guide rod, 69, a transmission mechanism I, 691, an upper rotating disc, 692, a lower gear, 6921, a convex column, 6922, a rotating disc connecting hole, 693, a connecting shaft, 70, a gear ring bearing, 701, an outer ring, 702, an inner ring, 71, a connecting block, 72, a bidirectional gear ring, 721, an extending block, 73, a driving motor, six, 731, a driving gear II, 74, a driving belt, 75, a through hole, 76, a reagent needle, 77, a code scanning window, 78, a box body identification code, 79, a code scanning device and an 80 refrigerator.

Detailed Description

The technical solution of the present invention is further explained in detail with reference to the accompanying drawings and specific embodiments.

Example (b): as shown in fig. 1, a full-automatic immunoassay analyzer comprises a sample conveying channel mechanism 1, a reagent tray mechanism 2, an incubation tray mechanism 3, a blending mechanism 4, an optical detection mechanism 5, a chip grabbing mechanism 6, a cup feeding mechanism 7 and a cleaning mechanism 8, wherein the reagent tray mechanism 2, the incubation tray mechanism 3, the blending mechanism 4, the optical detection mechanism 5, the chip grabbing mechanism 6, the cup feeding mechanism 7 and the cleaning mechanism 8 are arranged at one side of the sample conveying channel mechanism 1, a first cup grabbing mechanism 9 is further arranged between the cup feeding mechanism 7 and the incubation tray mechanism 3, and the first cup grabbing mechanism 9 is used for grabbing reaction cups from the cup feeding mechanism 7 to the incubation tray mechanism 3; a second cup grabbing mechanism 10 is further arranged between the blending mechanism 4 and the incubation disc mechanism 3, and the second cup grabbing mechanism 10 is used for transporting the reaction cup between the blending mechanism 4 and the incubation disc mechanism 3 in a rotating manner; a sample arm 11 is further arranged between the sample conveying channel mechanism 1 and the incubation disc mechanism 3, and the sample arm 11 is used for adding the sample conveyed by the sample conveying channel mechanism 1 into a reaction cup in the incubation disc 7; a reagent arm 12 is further arranged between the reagent disk mechanism 2 and the incubation disk mechanism 3, and the reagent arm 12 is used for sucking a proper amount of reagent from the reagent disk 16 and adding the reagent into a reaction cup in the incubation disk mechanism 3; a sample storage mechanism 13 and a sample taking and placing mechanism 14 are further arranged at one end of the sample conveying channel mechanism 1, the sampled samples are stored in the sample storage mechanism 13, and the sample taking and placing mechanism 14 can automatically sample from the sample storage mechanism 13 and send the samples to the sample conveying channel mechanism 1 or recycle the samples after sampling test on the sample conveying channel mechanism 1 to the sample storage mechanism 13. In this embodiment, the worker can automatically transport the sample between the sample storage mechanism 13 and the sample transport channel mechanism 1 back and forth through the sample taking and placing mechanism 14 as long as the sample after sampling is placed in the sample storage mechanism 13, without manual operation, thereby greatly improving the detection efficiency and being suitable for complex and huge detection tasks.

As shown in fig. 1, the analysis and detection method of the fully automatic immunoassay analyzer in this embodiment includes the steps of:

1) The first cup grabbing mechanism 9 transfers the reaction cup from the cup feeding mechanism 7 to the incubation disc mechanism 3;

2) The tested sample is placed on the sample storage mechanism 13, the sample is taken from the sample storage mechanism 13 to the sample taking and placing mechanism 14 by the sample taking and placing mechanism 14, then the sample is taken to the sample conveying channel mechanism 1 by the sample taking and placing mechanism 14, the sample is conveyed to a sampling position through the sample conveying channel mechanism 1, and then the sample is added into a reaction cup in the incubation disc mechanism 3 by the sample arm 11;

3) The reaction cup rotates to the position of a reagent arm 12 in the incubation disc mechanism 3, and the reagent arm 12 sucks a proper amount of reagent from the reagent disc mechanism 2 and adds the reagent into the reaction cup;

4) The reaction cup rotates to the position of the second cup grabbing mechanism 10 in the incubation disc mechanism 3, and the second cup grabbing mechanism 10 transfers the reaction cup to the mixing mechanism 4 for mixing uniformly;

5) Transferring the uniformly mixed reaction cups to an incubation disc mechanism 3 for incubation by a cup grabbing mechanism II 10;

6) Repeating the steps 3) to 5) for multiple times, and transferring the reaction cup from the cup grabbing mechanism I9 to the cleaning mechanism 8 for cleaning;

7) The washed reaction cup 18 is transferred back to the incubation tray by the cup grabbing mechanism I9, and then the luminescent substrate reagent is added by the reagent arm 12;

8) The chip grabbing mechanism 6 is used for taking and placing the chip into the optical detection mechanism 5, the sample arm 11 is used for sucking a proper amount of sample to be detected from the reaction cup and adding the sample to be detected into the chip, and the optical detection mechanism 5 is used for completing detection.

As shown in fig. 2 and 3, the sample storage mechanism 13 includes a storage platform 15 and a sample tube basket 16 placed on the storage platform 15, the storage platform 15 includes a table top 151, the sample tube basket 16 is placed on the table top 151, in order to solve the problem of positioning the sample tube basket 16 on the table top 151, a protrusion 152 is further provided on one end of the table top 151, and when the sample tube basket 16 is placed on the table top 151, the sample tube basket can be positioned by abutting contact on the protrusion 152.

As shown in fig. 4, a sample extracted from an object to be tested is placed in a sample tube 17, a plurality of sample tubes 17 are placed in a sample tube rack 18, the sample tube rack 17 includes a plurality of tube positions 171, and each tube position 171 is inserted into one sample tube 17, typically a group of ten tube positions. The sample tube holder 1 is made of a non-magnetically conductive, lightweight material, such as plastic or aluminum alloy. Each tube site 171 is a vertical cavity having a C-shaped cross-section. A tube position sensing piece 172 for detecting the position of the sample tube rack 1 is provided on one side of the bottom of each tube position 171. The tube position sensing piece 172 is a magnetic steel, a metal sheet or a reflecting plate, and is respectively matched with the hall sensor or the photoelectric sensor for detection. The position of the sample tube rack 1 in the automatic detection system is detected by the tube position sensing piece 172, and the movement of the sample tube rack 1 is controlled, so that the automatic detection system can position and sample the sample tube on the sample tube rack.

An identification code 19, such as a binary code or bar code, is provided at one end of the sample tube rack 18. The code scanning component on the automatic detection system can read the sample tube identification code 19, obtain the information of the sample tube rack and determine the items to be detected.

As shown in fig. 5, a fixed magnetic steel 20 is provided on the other end of the sample tube rack 18 away from the sample tube identification code 19, and a magnet is provided on the sample tube basket or the automatic detection system. Utilize magnet actuation fixed magnet steel 20, fix sample pipe support 1 actuation on sample pipe hand-basket or automatic check out system, prevent the position of sample pipe support and remove or the landing (can mention again when explaining sample pipe hand-basket).

Be provided with many convex strengthening ribs 21 in sample pipe support 18 bottom, strengthening rib 21 can enough increase the intensity of sample pipe support, can regard as the rack again, with the gear of drive mechanism or the protruding tooth cooperation on the belt, increase the engaging force between sample pipe support and the drive mechanism, can the removal and the location of accurate control sample pipe support, the sample part sample of being convenient for (can mention again when explaining sample pick and place the mechanism).

This embodiment has set up the sample tube hand-basket, can place a plurality of sample tube supports in a sample tube hand-basket after the sampling personnel has adopted the appearance, places sample tube hand-basket again and just need not manage after depositing the bench, can go to carry out other work, very big sampling work that has made things convenient for the sampling personnel has also improved the degree of automation of analysis appearance to detection efficiency has further been improved. As shown in fig. 6, sample tube carrier 16 includes a handle 161 and a rim 162, and rim 162 is rectangular or polygonal, preferably rectangular. The rim 162 includes a basket bottom plate 1621 and a basket enclosure 1622 disposed around the basket bottom plate 1621, three sides of the rectangular rim 162 are provided with basket enclosure 1622, and one side is an opening for the basket enclosure. The basket bottom plate 1621 is provided with a plurality of basket partition plates 22 arranged in parallel, the basket partition plates 22 are arranged towards the direction of the basket enclosure opening 204, the basket partition plates 22 divide the inner space of the basket 162 into a plurality of strip-shaped groove-shaped spaces 23, and one sample pipe support 18 is installed in each groove-shaped space 23. A basket chute 24 is disposed in each groove-shaped space 23 and on the basket bottom plate 1621, and the basket chute 24 facilitates the sample taking and placing mechanism 14 to extend into the basket 162 and the sample tube rack 18, so as to drive the sample tube rack 18 to move for a certain distance (described in detail later), thereby facilitating the automatic taking out or placing back of the sample tube rack 18.

As shown in fig. 5 and 6, a basket magnet 25 is provided on the basket enclosure 1622 located opposite to the opening of the basket enclosure in each groove-shaped space 23, and when the sample tube rack 18 is installed in the groove-shaped space 23, the basket magnet 25 and the fixed magnetic steel 20 on the sample tube rack 18 attract each other, thereby ensuring that the sample tube rack is prevented from being fixed in position. The rim 162 is made of a non-magnetic light material, such as plastic or aluminum alloy, so that a plurality of basket magnets 25 can be disposed on the rim 162, and a single magnetic field can be formed by the plurality of basket magnets 25.

The basket enclosure 1622 on one side of the basket is provided with a basket identification code which is a two-position code or a bar code. The automatic detection system can scan and read the basket lifting identification code, acquire the information of the sample pipe frame and determine the items to be detected.

Describing the sample taking and placing mechanism 14, as shown in fig. 2, fig. 7 and fig. 8, the sample taking and placing mechanism 14 includes a pushing component 26 and a taking and placing component 27, the pushing component 26 is disposed at the bottom of the platform 151 of the storage platform and is used for pushing the sample tube rack 18 out of the platform 151 onto the taking and placing component 27 or pushing the sample tube rack 18 retrieved from the taking and placing component 27 back onto the platform 151; the taking and placing component 27 is arranged at a position between the table top 151 and the sample conveying channel mechanism 1 and is used for conveying the sample pipe rack 18 to the sample arm 11 to wait for the sample arm 11 to take a sample or conveying the sample pipe rack 18 after the sample arm 11 finishes taking the sample back to the table top 151. The sample taking and placing mechanism 14 realizes the automatic access of the sample pipe rack 18 so as to meet the automation requirement of an automatic detection system.

The common station 28 and the preferential station 29 are arranged on the table-board 151, and because the pushing component 26 is arranged at the bottom of the table-board 151 of the storage table, in order to enable the pushing component 26 to contact the sample tube rack 18, a plurality of table-board through grooves 1511 are formed on each station, the sample tube baskets 16 are placed on the stations on the table-board, and each table-board through groove 1511 corresponds to one sample tube rack 18. When the pushing member 26 is operated, the pushing member 26 is sequentially pushed through a table top through groove 1511 and a basket chute 24 of the sample tube basket 16 and then contacts with a sample tube rack 18.

First, as shown in fig. 1 and 7, the longitudinal direction (X direction) along the length direction of the sample transport channel mechanism 1 is defined as a longitudinal direction, the width direction (Y direction) along the width direction of the sample transport channel mechanism 1 is defined as a transverse direction, and the height direction (Z direction) along the height direction of the sample transport channel mechanism 1 is defined as a vertical direction, and then the specific structure of the pushing member 26 is shown in fig. 7 and 9, the pushing member 26 includes a pushing member base 261 and a pushing block 262 slidably connected to the pushing member base 261, the pushing block 262 can move back and forth along the X direction, the pushing member base 261 is slidably connected to the bottom plate 153 of the storage table, and the pushing member base 261 can move back and forth along the Y direction, in this embodiment, the pushing member base 261 is slidably connected to the bottom plate 153 by a slide rail and a guide block mechanism one 30, and the pushing block 262 is slidably connected to the pushing member base 261 by a slide rail and a guide block mechanism two 31. The first power mechanism 32 is further arranged on the bottom plate 153, the first power mechanism 32 is a synchronous belt transmission mechanism and comprises a first driving motor 321 arranged on the bottom plate 153 and a first transmission belt 322 in matched transmission with the first driving motor 321, and the pushing component base body 261 is fixedly connected with the first transmission belt 322, so that the pushing component base body 261 can move back and forth along the Y direction under the driving of the first power mechanism 32, and the first driving motor can be a servo motor. The second power mechanism 33 is further arranged on the second pushing member substrate 261, the second power mechanism 33 is also a synchronous belt transmission mechanism and comprises a second driving motor 331 arranged on the second pushing member substrate 261 and a second transmission belt 332 in matched transmission with the second driving motor 331, the second pushing block 262 is fixedly connected with the second transmission belt 332, so that the second pushing block 262 can move back and forth along the X direction under the driving of the second power mechanism 33, and the second driving motor 331 can adopt a servo motor. The pushing block 262 is further provided with a telescopic push rod 263 capable of extending out of or retracting into the pushing block 262 from the pushing block 262, the telescopic push rod 263 can be extended and retracted by adopting a turbine screw rod lifter structure, the telescopic push rod 263 is equivalent to a screw rod of the turbine screw rod lifter structure, the pushing block 262 is further provided with a third driving motor 34 for controlling the telescopic push rod 263 to extend out of or retract into, and the third driving motor 34 can adopt a servo motor. Here, one end of the telescopic push rod 263 may be directly vertically connected to an output shaft of the driving motor three 34, and the rotation of the output shaft of the driving motor three 34 drives the other end of the telescopic push rod 263 to rotate around one end thereof, so as to drive the telescopic push rod 263 to rotate by a certain angle to extend out of the pushing block 262 or to rotate reversely by a certain angle to retract into the pushing block 262. In order to accurately control the position of the pushing member base 261 in the Y direction, a first positioning plate 35 is further provided on the bottom plate 153, and a first positioning sensor 36 is further provided on the pushing member base 261, and the first positioning plate 35 and the first positioning sensor 36 are matched with each other, so that the position of the pushing member base 261 in the Y direction can be accurately controlled. In order to accurately control the position of the pushing block 262 in the X direction, a second positioning plate 37 is further arranged on the pushing component base 261, a second positioning sensor 38 is further arranged on the pushing block 262, and the second positioning plate 37 and the second positioning sensor 38 are matched with each other, so that the position of the pushing block 262 in the X direction can be accurately controlled.

The specific structure of the pick-and-place unit 27 is described as follows: as shown in fig. 7 and 10, the pick-and-place unit 27 includes a pick-and-place unit base 271, the pick-and-place unit base 271 is slidably connected to the bottom plate 153 through a slide rail and a third guide block mechanism 39, a third power mechanism 40 is further disposed on the bottom plate 153, the third power mechanism 40 is also a synchronous belt transmission mechanism, and includes a third driving motor 401 disposed on the bottom plate 153 and a third driving belt 402 in cooperation with the third driving motor 401, the pick-and-place unit base 271 is fixedly connected to the third driving belt 402, so that the pick-and-place unit base 271 can move back and forth along the Y direction under the driving of the third power mechanism 40, and the third driving motor 401 can adopt a servo motor. In order to accurately control the position of the taking-placing component base 271 in the Y direction, a third positioning plate 42 is further disposed on the bottom plate 153, and a third positioning sensor 43 is further disposed on the taking-placing component base 271, so that the position of the taking-placing component base 271 in the Y direction can be accurately controlled by the cooperation of the third positioning plate 42 and the third positioning sensor 43. The taking and placing component base body 271 is further provided with a conveying channel 272 for conveying the sample tube rack 18, the conveying channel 272 is used for conveying the sample tube rack through a synchronous belt transmission mechanism 41 which is arranged on the taking and placing component base body 271 and is positioned at the bottom of the conveying channel 272, the synchronous belt transmission mechanism 41 comprises a driving motor IV 411 and a conveying belt 412 which is in matched transmission with the driving motor IV 411, and the sample tube rack 18 is conveyed through the conveying belt 412. Be provided with a plurality of driving teeth on the surface of conveyer belt 412, through a plurality of strengthening ribs 21 looks meshing cooperation transmission of a plurality of driving teeth and sample pipe support 18 bottom to increase the frictional force between sample pipe support and the conveyer belt, prevent to skid and lead to the sample pipe support can not convey to the target in place. The pick-and-place member base 271 is further provided with a sample tube rack code reader 44 and a sample tube code reader 45, and the sample tube rack code reader 44 is used for reading the identification code 19 on the end of the sample tube rack, thereby determining which sample tube rack needs to be picked and sent. The sample tube code reader 45 is used to read the tube position sensing strip 172 on one sample tube rack, so as to determine the position of the sample tube rack in the conveying channel 272.

Next, a specific structure of the specimen transport path mechanism 1 is described, and as shown in fig. 11 and 12, the specimen transport path mechanism 1 includes a path frame 111 and a plurality of transport paths 112 provided on the path frame 111, and in this embodiment, three transport paths 112 are provided, one of which is a preferential feed path 1121, one of which is a normal feed path 1122, and one of which is a recovery path 1123. Each of the transport paths 112 is provided with a sample transport belt 46, and the rack 18 transported from the transport belt 412 of the pick-and-place section 27 is transported to the sample transport belt 46 of an input path, and then transported to the sampling site of the sample arm 11 through the input path for sampling. As shown in fig. 10 and 11, in order to control the position between the pick-and-place unit 27 and the specific conveying channel 112, a positioning sensor four 48 is further disposed on the pick-and-place unit base 271, a positioning plate four 49 is further disposed on the bottom plate 153, and the positioning plate four 49 and the positioning sensor four 48 are matched with each other, so that the position between the pick-and-place unit 27 and the specific conveying channel 112 can be precisely controlled.

As shown in fig. 12, a channel switching member 47 is further provided at one end of the transport channel, and the rack 18 from which samples have been taken from the preferential feed channel 1121 or the normal feed channel 1122 can be switched to the collection channel 1123 by the channel switching member 47, and then transported to the pick-and-place member 27 through the collection channel 1123. As shown in fig. 13 and 14, a channel side guard 50 is disposed on both sides of each transport channel, one end of the sample transport belt 46 in the transport channel is exposed out of the channel side guard 50, the channel switching member 47 is disposed at one end of the sample transport belt 46 exposed out of the channel side guard 50, the channel switching member 47 includes a component substrate 471 disposed at one end of the sample transport belt 46 exposed out of the channel side guard 50 and a channel switching synchronous belt transmission mechanism disposed on the component substrate 471, a sliding arm 472 is slidably connected to the guide block mechanism iv 51 on the component substrate 471 through a sliding rail, and one end of the sliding arm 472 is connected to a transport belt iv 473 of the channel switching synchronous belt transmission mechanism, so that the component substrate can move back and forth in the Y direction under the driving of the channel switching synchronous belt transmission mechanism. The other end of the sliding arm 472 is provided with a U-shaped card-receiving body 474, and the U-shaped card-receiving body 474 is horizontally disposed with the U-shaped opening thereof facing the conveying passage. In order to control the position of the U-shaped card slot body 474 moving back and forth in the Y direction, a positioning sensor five 53 is further provided on the sliding arm 472, a positioning plate five 54 is further provided on the component base plate 471, and the positioning plate five 54 and the positioning sensor five 53 are matched with each other, so that the position of the U-shaped card slot body 4744 moving back and forth in the Y direction can be accurately controlled.

The positioning sensor can adopt a photoelectric sensor, the positioning plate can adopt angle steel provided with a plurality of notches, and when the photoelectric sensor passes through the notches of the positioning plate, the photoelectric sensor detects pulse signals and converts the pulse signals into position signals through a control system.

The automatic sampling step in this embodiment is: as shown in fig. 2 and 3, the worker loads a plurality of sample tubes sampled from the object to be measured into sample tube racks, loads a plurality of sample tube racks into the sample tube baskets 16, and places the sample tube baskets 16 on the common station 28 or the priority station 29 on the top 151 of the storage table. As shown in fig. 8 and fig. 15 to fig. 17, the telescopic push rod 263 of the pushing component 26 is controlled to extend, the telescopic push rod 263 sequentially passes through one table-board through slot 1511 on the table-board 151 and one basket chute 24 of the sample tube basket 16 to contact with one sample tube rack 18, and then the second power mechanism 33 of the pushing component 26 is controlled to operate, so that the one sample tube rack 18 is pushed out to the conveyor belt 412 of the pick-and-place component 27 by the telescopic push rod 263; when the sample tube code reader 45 of the pick-and-place unit 27 detects that the sample tube rack 18 enters the conveyor belt 412, the conveyor belt 412 of the pick-and-place unit 27 is controlled to move, so that the sample tube rack 18 is conveyed to the conveyor belt 412 under the pushing action of the telescopic push rod 263 and the driving action of the conveyor belt 412.

As shown in fig. 10 and 12, after the one sample tube rack 18 is conveyed onto the conveyor belt 412, the conveyor belt 412 is controlled to stop operating, the pick-and-place component base 271 of the pick-and-place component 27 is controlled to move to a feeding channel of the sample conveying channel mechanism 1, then the conveyor belt 412 is controlled to operate again, the one sample tube rack 18 is conveyed onto the sample conveyor belt 46 in the feeding channel by the driving of the conveyor belt 412 and the driving of the sample conveyor belt 46 in the feeding channel, the one sample tube rack 18 is conveyed to the sample arm sampling position by the sample conveyor belt 46, and the sample conveyor belt 46 stops operating, and sampling is performed by the sample arm.

As shown in fig. 12 and 13, after the sample arm finishes sampling, the sample conveyor 46 is controlled to move, the one sampled rack 18 is conveyed to the U-shaped slot body 474 of the channel switching unit 47, then the sample conveyor 46 is controlled to stop moving, the sliding arm 472 of the channel switching unit 47 is controlled to move, the U-shaped slot body 474 and the one sampled rack 18 are driven to move together to the sample conveyor of the recovery channel 1123, then the sample conveyor of the recovery channel 1123 is controlled to move the one sampled rack 18 to the conveyor 412 of the pick-and-place unit 27, then the pick-and-place unit 27 is controlled to move to the common station 28 or the sample tube carrier 16 of the priority station 29, then the one sampled rack 18 is driven by the conveyor 412 of the pick-and-place unit 27 to move to one trough-shaped space 23 of the sample tube carrier 16, and after one end of the one sampled rack 18 enters the trough-shaped space 23, the one sampled rack 18 is driven by the telescopic push rod 263 to move completely to the sample tube carrier 23 of the sample tube carrier 16, and the sample tube carrier 18 is driven by the trough-shaped space 23.

The automatic sampling method in the embodiment can store a large number of sample pipe frames, increase the number of samples, and quickly convey the sample pipe frames to sampling positions in the automatic detection system for sampling in a mode that the pushing component and the taking and placing component are matched for relay, so that the requirement of quickly inputting the sample pipe frames is met, the structure of the automatic detection system main body is simplified, and the automatic detection system is more compact. After taking out the appearance, can be with the quick recovery processing that carries on of sample pipe support, further increased detection efficiency. The sample tube rack is provided with a plurality of one-way conveying channels and is used for conveying different detection items. The sample pipe support can line up in one-way transfer passage, carries out orderly conveying, improves the conveying quantity and the transfer rate of sample pipe support, has saved the transfer time, has improved detection speed.

The applicant also optimized a reagent disk mechanism in which reagents required for reactions are stored and mounted on a reagent disk, and thus the reagent disk of the fully automatic immunoassay analyzer is a storage and supply unit of reagents required for reactions. When the reagent is sucked, the reagent box on the reagent disk is rotated to the position where the reagent needle needs to suck the reagent through the rotation of the reagent disk, and then the reagent in the reagent box is sucked into the incubation disk through the reagent needle to react with the sample. Generally, reagent boxes on a reagent tray have different structures such as a split type structure and an integrated type structure, a plurality of mutually independent reagent cavities are arranged in the integrated type reagent box, the upper end opening of each reagent cavity is convenient for a reagent needle to suck reagents, and different types of reagents are filled in each reagent cavity; a plurality of reagent boxes are arranged on the reagent disk, and the rotation of the reagent disk can drive the plurality of reagent boxes to rotate together. Among the reagents, there is a reagent (such as magnetic bead reagent, immunomagnetic bead, magnetic bead solid phase carrier) which is easy to precipitate and accumulate due to its characteristics, and it needs to rotate continuously during the test absorption process to prevent the precipitation and accumulation. However, in the existing integrated reagent kit, only when the reagent disk rotates, the reagent kit can rotate together with the reagent disk, the reagent in the reagent kit also moves together with the reagent disk, and when the reagent needle sucks the reagent from the reagent kit, the reagent disk and the reagent kit cannot move, so that the reagent which is easy to precipitate and accumulate in the reagent kit stops rotating, and the precipitation and accumulation phenomena are easy to occur in the process of sucking the reagent, thereby affecting the test result.

The reagent disk structure in this embodiment is: as shown in fig. 18 and 19, the reagent disk mechanism includes a housing 55, a rotary disk 56 rotatably provided inside the housing 55, and a plurality of reagent cartridges 57 provided on the rotary disk 56. The housing 55 comprises a cylindrical housing body 551 and a housing cover 552 arranged at an opening at the top end of the housing body 551, the inner cavity of the housing body 551 is a main working area of the reagent disk, and only the top end of the housing body 551 is an opening; the cover 552 is used to close the top opening of the housing body 551, so that the inner cavity of the housing body 551 becomes a relatively closed working space. In order to ensure the temperature of the inner cavity of the housing body 551, as shown in fig. 20, in the present embodiment, the housing body 551 is designed to be a double-layer structure, and includes an outer housing 5511 and an inner housing 5512, and the heat insulating material 58 is disposed between the outer housing 5511 and the inner housing 5512, where only one layer of the housing body may be disposed, and the heat insulating material is further mounted outside the housing body. However, the double-layer shell designed by the embodiment has a better heat preservation effect.

As shown in fig. 19, a spindle bearing seat 59 is installed at the bottom of the housing body 551, the spindle 60 is vertically arranged and rotatably connected in the spindle bearing seat 59, one end of the spindle 60 extends into the housing body to be connected with the turntable 56, the other end of the spindle 60 is exposed out of the bottom of the housing body, a main gear 61 is installed at the other end of the spindle 60, the main gear 61 is in transmission connection with a power mechanism four in a matching manner, and the main gear 61, the spindle 60 and the turntable 56 can be sequentially driven to rotate by the power mechanism four. In the present embodiment, the fourth power mechanism employs a fifth driving motor 66 (not shown in fig. 19, but labeled in fig. 21), which may be a servo motor, and a first driving gear on an output shaft of the fifth driving motor is in a fit-transmission connection with the main gear 61 through a transmission belt 74. An induction disc 62 is further disposed on the bottom end surface of the main gear 61, a sensor 63 is disposed at the bottom of the housing body 551 and at the position of the induction disc 62, and the rotation angle position and the zero point position of the rotary disc 56 can be controlled by the cooperation of the induction disc 62 and the sensor 63. Specifically, as shown in fig. 21, the sensor 63 may be configured as a first sensor 631 and a second sensor 632, wherein the first sensor 631 is configured to detect a zero position of the turntable, the second sensor 632 is configured to detect a rotation angle position of the turntable, a plurality of sensing grooves 621 are circumferentially disposed on the sensing disk 62, the sensor 63 employs a photoelectric sensor, and when the photoelectric sensor passes through the sensing grooves 621, the photoelectric sensor detects a pulse signal and converts the pulse signal into a position signal through a control system, so that the photoelectric sensor can determine the rotation angle position and the zero position by matching with the sensing grooves. A plurality of legs 64 are also provided at the bottom of the housing body 551 for placing the reagent disk on the ground.

As shown in fig. 22 to 24, the axial section of the turntable 56 is an inverted U-shape, and includes a circular turntable body 561 and a turntable cylinder 562 disposed on an inner ring of the turntable body 561, where the turntable body 561 and the turntable cylinder 562 are an integral structure. Be provided with a plurality of installation draw-in grooves 65 that are used for installing the kit on carousel body 561, the shape of installation draw-in groove 65 is unanimous with the shape of kit, and a plurality of installation draw-in grooves 65 distribute in proper order along carousel circumference and be provided with a whole circle on carousel body 561, connect in the installation draw-in groove behind every kit 57 cards income installation draw-in groove 65, also can link together through other modes such as screw between kit and the installation draw-in groove here. As shown in fig. 19 and 20, one end of spindle 60 is connected to a turntable cylinder 562 of turntable 56, thereby connecting spindle 60 and turntable 56 together. As can be seen from the figure, the middle position of the turntable 56 is set as the turntable cylinder 562, so that the inner cavity portion of the turntable cylinder 562 is an installation space to accommodate the lower spindle bearing seat 59 and other components such as a power mechanism five for driving the reagent tube to rotate, which will be mentioned later.

As shown in fig. 25 and 26, the reagent kit 57 includes a kit body 571, the kit body 571 is arc-shaped, a plurality of reagent cavities 67 independent from each other are arranged inside the kit body 571, and an opening 671 is arranged at the top of each reagent cavity 67, so that a reagent needle can be inserted into and suck up a reagent. In the present embodiment, three reagent chambers one 67 are provided, and the reagent chambers one 67 are used for loading general reagents. A reagent tube 68 is rotatably connected to one end of the cartridge 571, a second reagent chamber 681 is arranged inside the reagent tube, and an opening second 682 is also arranged at the top of the second reagent chamber 681. The reagent tube 68 is used to carry reagents that tend to precipitate and accumulate. Here, one or more reagent tubes 68 may be provided. In the present embodiment, one reagent tube 68 is provided.

As shown in fig. 23, a first transmission mechanism 69 is disposed on a bottom surface of one end of each mounting slot 65, and a bottom of each reagent tube 68 is connected to one first transmission mechanism 69. As shown in fig. 25 to 27, a cylindrical tube mounting cavity 572 is provided at one end of the cartridge body 571, the reagent tube 68 includes a tube 683, a flange 684 is provided at a top of the tube 683, a guide rod 685 is provided at an outer bottom of the tube 683, the tube 683 is inserted into the tube mounting cavity 572 in a loose-fitting connection, and the flange 684 is in contact with a top end surface of the tube mounting cavity 572, so that the reagent tube 68 is rotatably connected to one end of the cartridge body 571.

As shown in fig. 27 and fig. 28, the first transmission mechanism 69 is rotatably connected to a bottom surface at one end of the mounting slot 65, the first transmission mechanism 69 includes an upper rotary disc 691, a lower gear 692, and a connecting shaft 693 connecting the upper rotary disc 691 and the lower gear 692, the upper rotary disc 691 is located at an inner bottom of the mounting slot 65, the lower gear 692 is located at an outer portion of the mounting slot 65 (i.e., an outer bottom of the rotary disc body 561), and the connecting shaft 693 passes through the slot through hole 651 at the bottom of the mounting slot 65 to connect the upper rotary disc 691 and the lower gear 692. The structure of the rotational connection of the first transmission mechanism 69 can be various, and can be rotationally connected through clearance fit between the connecting shaft and the slot through hole, or like this embodiment, a convex pillar 6921 is provided on the top surface of the lower gear 692, and one end of the connecting shaft 693 is inserted into the convex pillar 6921 to be connected with the lower gear 692. The convex column 6921 of the lower gear 692 is inserted into the card slot through hole 651 and is in clearance fit and rotary connection with the card slot through hole 651. A turntable connecting hole 6922 is further formed in the upper turntable 691, and a guide rod 685 at the outer bottom of the pipe body 683 is inserted into the turntable connecting hole 6922, so that the reagent pipe 68 is in transmission connection with the first transmission mechanism 69.

As shown in fig. 29 to 31, a ring gear bearing 70 is further provided on the inner bottom surface of the housing body 551 in the vicinity of the spindle bearing base 59, the ring gear bearing 70 is horizontally disposed, an outer ring 701 of the ring gear bearing 70 is fixed to the inner bottom surface of the housing body 551 via a connecting block 71, and an inner ring 702 of the ring gear bearing 70 is connected to the bidirectional ring gear 72, thereby rotatably connecting the bidirectional ring gear 72 to the inner bottom surface of the housing body 551. In the present embodiment, the inner ring and the outer ring of the bidirectional ring gear 72 are both provided with gears, which are also horizontally disposed, and the lower end thereof is provided with an extension block 721, and the bidirectional ring gear 72 is connected to the inner ring 702 of the ring gear bearing 70 by fixing the extension block 721 to the inner ring of the ring gear bearing 70.

The fifth power mechanism is a driving motor six 73 which is arranged on the inner bottom surface of the shell body 551 and is located near the spindle bearing seat 59, the driving motor six 73 can adopt a servo motor, the driving motor six 73 is connected to the inner bottom surface of the shell body 551 through a bracket (not shown in the figure), and the driving motor six 73 is located in the inner cavity of the rotary table barrel 562. A second driving gear 731 is fixedly connected to an output shaft of the sixth driving motor 73, the second driving gear 731 is in meshing transmission with an inner ring gear of the bidirectional gear ring 72, and a lower gear 692 of each first transmission mechanism 69 is in meshing transmission with an outer ring gear of the bidirectional gear ring 72. The bidirectional gear ring 72, the gear ring bearing 70 and the driving gear II 731 form a transmission mechanism II, that is, the driving motor six 73 can drive the reagent tube 68 to rotate by the cooperation of the transmission mechanism II and the transmission mechanism I. The diameter of drive gear two 731 and lower gear 692 are each smaller than the diameter of bidirectional ring gear 72, and the weight of bidirectional ring gear 72 is also greater than the weight of drive gear two 731 and lower gear 692.

As shown in fig. 19, 30 and 31, the specific driving and rotating process of this embodiment is as follows: firstly, controlling a driving motor five of the power mechanism four to act, so as to sequentially drive the first driving gear, the transmission belt 74, the main gear 61 and the main shaft 60 to rotate, and finally driving the turntable 56 to rotate through the rotation of the main shaft 60; at this time, the driving motor six 73 does not operate, and the turntable 56 drives the lower gear 692 of the transmission mechanism one 69 connected to the reagent tube 68 to rotate along the outer ring gear of the bidirectional gear ring 72, so as to drive the reagent tube 68 containing the magnetic bead reagent to rotate. Here, the driving motor six 73 is preferably a servo motor of a braking device, and is similar to a motor structure of a winch, when the turntable 56 rotates, the bidirectional gear ring 72 is controlled to be fixed by the braking device, so that the lower gear 692 of the transmission mechanism one 69 rotates along the outer ring gear of the bidirectional gear ring 72 at a higher speed, thereby also enabling the reagent tube 68 to rotate at a higher speed.

When a certain reagent box on the rotary disc 56, which needs to absorb reagent, rotates to the position, the driving motor is controlled to stop operating, the rotary disc 56 stops rotating, at the moment, the driving motor six 73 is controlled to operate, so that the driving gear two 731, the bidirectional gear ring 72, the lower gear 692 of the transmission mechanism one 69, the connecting shaft 693 of the transmission mechanism one 69 and the upper rotary disc 691 of the transmission mechanism one 69 are sequentially driven to rotate, finally, the reagent tube 68 is driven to rotate through the rotation of the upper rotary disc 691 of the transmission mechanism one 69, and therefore when the rotary disc 56 does not rotate, the reagent tube 68 containing magnetic bead reagent can continuously rotate, and the phenomenon of deposition and accumulation cannot occur.

As shown in fig. 25 and 32, the case cover 552 is provided with through holes 75 for facilitating reagent needle to suck reagent, and the number of the through holes 75 is the same as the number of the first openings and the second openings of the reagent tubes on one reagent cartridge, for example, in the present embodiment, three first openings and one second opening are provided on one reagent cartridge, and the total number is four, so that the through holes 75 are also provided in four. When reagent in a certain reagent box needs to be sucked, the rotating disc is controlled to rotate, so that the reagent box rotates to the position where the opening I and the opening II correspond to the through holes in the shell cover, at the moment, the rotating disc is controlled to stop rotating, and then the reagent needle is inserted into the through hole and the opening in the reagent box to suck the reagent.

In this embodiment, the reagent cartridges are arranged in an arc shape, and the first openings and the second openings are arranged in an arc shape (i.e., the central points of the openings are arranged along the arc line C in fig. 9), so that the through holes 75 on the cover 552 are also arranged in an arc shape. In the prior art, as shown in fig. 33, the reagent kit 57 is mostly rectangular, the openings provided thereon are also linearly distributed, and the reagent needle 76 is mounted on the reagent arm, so the movement track L of the reagent needle 76 swings in an arc shape, when the reagent needle 76 swings to one opening K1 on the reagent kit 57, the reagent needle is inserted into the opening K1 to suck the reagent, but when another opening K2 needs to be sucked, the reagent arm does not suck the reagent, and the reagent arm needs to be operated again, so that the opening K2 is located on the movement track L of the reagent needle 76 to suck the reagent, thereby increasing the mechanical operation steps and reducing the detection efficiency. In the embodiment, the reagent cartridges and the openings thereof are arranged in an arc shape, and the plurality of arc-shaped reagent cartridges are sequentially arranged on the reagent tray along the circumferential direction of the reagent tray, as shown in fig. 24 and 34, so that each opening is located on the movement track L of the reagent needle 76, and therefore, in the action of sucking the reagent, the reagent needle 76 only needs to sequentially suck along the movement track L, and no redundant action is needed, thereby greatly improving the detection efficiency.

As shown in fig. 18 and 25, a code scanning window 77 is formed on the circumferential surface of the housing body 551, a cartridge identification code 78 is provided on the end surface of the cartridge 571 of each cartridge, and the cartridge identification code 78 may be a bar code or a two-dimensional code. A code scanning device 79 is also arranged outside the shell body 551 and at the position of the code scanning window. Thus, when a reagent cartridge is rotated to the code scanning window, the position of a specific reagent cartridge can be known by scanning the reagent cartridge by the code scanning device 79.

As shown in fig. 21, refrigerator 80 is further provided on the outer bottom surface of housing body 551, and semiconductor refrigerator can be used as refrigerator 80.

In conclusion, the automatic sampling method and the automatic sampling mechanism in the full-automatic immunoassay analyzer are optimized, so that a large number of sample pipe frames can be stored, and the number of samples is increased; the sample pipe frame is quickly conveyed to a sampling position in the automatic detection system for sampling in a mode that the pushing component and the taking and placing component of the sample taking and placing mechanism are matched for relay, so that the requirement of quickly inputting the sample pipe frame is met, the structure of the main body of the automatic detection system is simplified, and the automatic detection system is more compact. After taking out the appearance, can be with the quick recovery processing that carries on of sample pipe support, further increased detection efficiency. The sample tube rack is provided with a plurality of one-way conveying channels and is used for conveying different detection items. The sample pipe support can line up in one-way transfer passage, carries out the conveying in order, improves the conveying quantity and the transfer rate of sample pipe support, has saved the transfer time, has improved detection speed. Optimize reagent dish mechanism, rotate alone on the integrated form kit and connect the reagent pipe that loads the easy deposit and pile up reagent, the rethread sets up drive mechanism one and matches with drive mechanism two, make reagent pipe couple together through drive mechanism one and drive mechanism two and the transmission of servo drive motor two, and thus, when reagent needle absorbs reagent, when the carousel stall, also can drive the rotation that the reagent pipe does not stop through servo drive motor two, thereby when whole reagent dish is motionless, also can make the loading have the easy reagent pipe that deposits and pile up the reagent and rotate that does not stop, thereby avoided absorbing reagent in-process, the easy deposit is piled up reagent and is appeared and deposit and pile up the phenomenon, the accuracy of test result has been guaranteed. Through the specific structural design of the first transmission mechanism and the second transmission mechanism, the continuous rotation function of the reagent tube is further ensured. The rotation angle position of the rotary disc can be monitored and controlled in real time by arranging the induction disc and the sensor, so that the specific rotation position of the reagent box on the rotary disc can be controlled. The reagent box is optimized, the reagent box and the openings on the reagent box are arranged in an arc shape, and the reagent boxes with a plurality of arc shapes are sequentially arranged on the reagent plate along the circumferential direction of the reagent plate, so that the movement track of the reagent needle coincides with the arc arrangement positions of the openings, the reagent needle can suck the reagent conveniently, the suction time is shortened, and the working efficiency is improved.

The term "plurality" as used in this embodiment means a number of "two or more". The above embodiments are provided for illustrative purposes only and not for limiting the present invention, and those skilled in the art can make various changes and modifications without departing from the spirit and scope of the present invention, and therefore all equivalent technical solutions should fall within the scope of the present invention, and the scope of the present invention should be defined by the claims.

Claims

1. A full-automatic immunity analyzer comprises a sample conveying channel mechanism, a reagent tray mechanism, an incubation tray mechanism, a blending mechanism, an optical detection mechanism, a chip grabbing mechanism, a cup feeding mechanism and a cleaning mechanism, wherein the reagent tray mechanism, the incubation tray mechanism, the blending mechanism, the optical detection mechanism, the chip grabbing mechanism, the cup feeding mechanism and the cleaning mechanism are arranged at one side of the sample conveying channel mechanism; a second cup grabbing mechanism is arranged between the blending mechanism and the incubation disc mechanism; a sample arm is also arranged between the sample conveying channel mechanism and the incubation disc mechanism; still be provided with reagent arm, its characterized in that between reagent dish mechanism and hatching dish mechanism: a sample storage mechanism and a sample taking and placing mechanism are further arranged at one end of the sample conveying channel mechanism; the sample is stored in the sample storage mechanism, and the sample taking and placing mechanism can automatically take the sample from the sample storage mechanism and send the sample to the sample conveying channel mechanism or recycle the sample taken by the sample conveying channel mechanism into the sample storage mechanism.

2. The fully automatic immunoassay analyzer of claim 1, wherein: the sample storage mechanism comprises a storage table and a sample tube basket placed on the storage table, and a plurality of sample tube racks are placed in the sample tube basket.

3. The fully automatic immunoassay analyzer of claim 2, wherein: the sample tube lifting basket comprises a lifting handle and a basket frame, the basket frame comprises a lifting basket bottom plate and a lifting basket enclosure arranged on the periphery of the lifting basket bottom plate, three surfaces of the basket frame are provided with the lifting basket enclosure, and one surface of the basket frame is provided with an opening of the lifting basket enclosure; the basket bottom plate is provided with a plurality of basket partition plates which are arranged in parallel, the basket partition plates are arranged towards the opening direction of the basket enclosure, the inner space of the basket frame is divided into a plurality of strip-shaped groove-shaped spaces by the basket partition plates, and each groove-shaped space is provided with a sample pipe frame; and a basket sliding groove is arranged in each groove-shaped space and on the basket bottom plate.

4. The fully automatic immunoassay analyzer of claim 3, wherein: the sample taking and placing mechanism comprises a pushing component and a taking and placing component, and the pushing component is arranged at the bottom of the table top of the storage table; the pick-and-place component is arranged at a position between the table top and the sample conveying channel mechanism.

5. The fully automatic immunoassay analyzer of claim 4, wherein: a plurality of stations are arranged on the table board, a plurality of table board through grooves are formed in each station, the sample tube lifting basket is placed on the station on the table board, and each table board through groove corresponds to one sample tube frame;

the pushing component comprises a pushing component base body and a pushing block connected to the pushing component base body in a sliding mode, and the pushing component base body is connected to the bottom plate of the storage table in a sliding mode; the bottom plate is also provided with a first power mechanism for driving the pushing component substrate to move, and the pushing component substrate can move back and forth under the driving of the first power mechanism; the pushing part base body is also provided with a second power mechanism for driving the pushing block to move, and the pushing block can move back and forth under the driving of the second power mechanism; the pushing block is also provided with a telescopic push rod which can extend out of or retract into the pushing block, and the pushing block is also provided with a driving motor III for controlling the telescopic push rod to extend out of or retract into the pushing block;

the taking and placing component comprises a taking and placing component base body, the taking and placing component base body is connected to the bottom plate in a sliding mode, a third power mechanism is further arranged on the bottom plate, and the taking and placing component base body can move back and forth under the driving of the third power mechanism; a conveying channel for conveying the sample pipe rack is further arranged on the taking and placing component base body, and a conveying belt for conveying the sample pipe rack is arranged at the bottom of the conveying channel;

6. The fully automatic immunoassay analyzer of claim 1, wherein: the sample conveying channel mechanism comprises a channel rack and a plurality of conveying channels arranged on the channel rack;

the sample storage mechanism is positioned at one end of the sample conveying channel mechanism, and a channel switching component is also arranged at the other end of the sample conveying channel mechanism, and the sample tube rack on any one conveying channel can be switched to the other conveying channel through the channel switching component.

7. The fully automatic immunoassay analyzer of claim 6, wherein: the channel switching part comprises a part substrate and a channel switching synchronous belt transmission mechanism arranged on the part substrate, a sliding arm is connected to the part substrate in a sliding mode, one end of the sliding arm is connected with the channel switching synchronous belt transmission mechanism, so that the sliding arm can move back and forth under the driving of the channel switching synchronous belt transmission mechanism, a U-shaped clamping groove body is further arranged at the other end of the sliding arm, the U-shaped clamping groove body is horizontally arranged, and the U-shaped opening direction of the U-shaped clamping groove body faces towards the conveying channel.

8. The fully automatic immunoassay analyzer of claim 1, wherein: the reagent disk mechanism comprises a shell, a rotary disk and a plurality of reagent boxes, wherein the rotary disk is rotatably arranged in the shell, the plurality of reagent boxes are arranged on the rotary disk, the rotary disk is connected with a driving motor V in a matching mode, each reagent box comprises a box body, a plurality of mutually independent reagent containing cavities I are arranged in the box body, a reagent pipe is further rotatably connected to one end of the box body, and a reagent containing cavity II is arranged in the reagent pipe; the reagent tube testing device is characterized in that a plurality of first transmission mechanisms are arranged on the rotary disc, the bottom of each reagent tube is connected with one first transmission mechanism, a second transmission mechanism and a sixth driving motor are further arranged inside the shell, the second transmission mechanism is in transmission connection with the first transmission mechanism in a matched mode, and the reagent tubes are in transmission connection with the sixth driving motor in a matched mode through the first transmission mechanism and the second transmission mechanism.

9. The fully automatic immunoassay analyzer of claim 8, wherein: the first transmission mechanism comprises an upper rotary table, a lower gear and a connecting shaft connected with the upper rotary table and the lower gear, the upper rotary table and the lower gear are respectively located on two opposite sides of the rotary table, the connecting shaft penetrates through the rotary table, one end of the connecting shaft is connected with the upper rotary table, and the other end of the connecting shaft is connected with the lower gear.

10. The fully automatic immunoassay analyzer of claim 9, wherein: the transmission mechanism II comprises a bidirectional gear ring, a gear ring bearing and a driving gear II, the gear ring bearing is arranged in the shell, an outer ring of the gear ring bearing is fixedly connected to the inner bottom of the shell, an inner ring of the gear ring bearing is connected with the bidirectional gear ring, so that the bidirectional gear ring is rotatably connected to the inner bottom of the shell, a driving motor II is further arranged in the shell, and the driving gear II is arranged on an output shaft of the driving motor II; and the second driving gear is in meshed transmission with the inner ring gear of the bidirectional gear ring, and the lower gear of each first transmission mechanism is in meshed transmission with the outer ring gear of the bidirectional gear ring, so that the second transmission mechanism is in matched transmission connection with the first transmission mechanism.

11. The fully automated immunoassay analyzer of claim 8, wherein: the shell comprises a shell body and a shell cover arranged at an opening at the top end of the shell body; the top of each reagent containing cavity I is provided with an opening I, a reagent containing cavity II is arranged inside the reagent pipe, and the top of the reagent containing cavity II is also provided with an opening II; through holes convenient for reagent needles to suck reagents are arranged on the shell cover, and the number of the through holes is consistent with the number of the first openings on one reagent kit and the second openings of the reagent tubes.

12. The fully automatic immunoassay analyzer of claim 11, wherein: every kit is the arc setting and a plurality of openings one and the opening two of reagent pipe on every kit also are the arc and arrange, and a plurality of curved kits set gradually on the reagent dish along the circumference of reagent dish, correspond, and be a plurality of on the cap the through-hole also is the arc and arranges.

13. An analysis detection method of the fully automatic immunity analyzer according to any one of claims 1 to 12, characterized in that: the steps of the analytical detection method include:

6) Repeating the steps 3) to 5) for multiple times, and transferring the reaction cup to a cleaning mechanism for cleaning operation by a cup grabbing mechanism;

14. The analytical detection method according to claim 13, wherein: the sample storage mechanism comprises a storage platform and a sample tube basket placed on the storage platform, and a plurality of sample tube racks are placed in the sample tube basket; the sample tube lifting basket comprises a lifting handle and a basket frame, the basket frame comprises a lifting basket bottom plate and a lifting basket enclosure arranged on the periphery of the lifting basket bottom plate, three surfaces of the basket frame are provided with the lifting basket enclosure, and one surface of the basket frame is provided with an opening of the lifting basket enclosure; the basket bottom plate is provided with a plurality of basket partition plates which are arranged in parallel, the basket partition plates are arranged towards the opening direction of the basket enclosure, the inner space of the basket frame is divided into a plurality of strip-shaped groove-shaped spaces by the basket partition plates, and each groove-shaped space is provided with a sample pipe frame; a basket sliding groove is arranged in each groove-shaped space and positioned on the basket bottom plate; the sample taking and placing mechanism comprises a pushing component and a taking and placing component, and the pushing component is arranged at the bottom of the table top of the storage table; the taking and placing component is arranged between the table top and the sample conveying channel mechanism; a plurality of stations are arranged on the table board, a plurality of table board through grooves are formed in each station, the sample tube lifting basket is placed on the station on the table board, and each table board through groove corresponds to one sample tube frame; the pushing component comprises a pushing component base body and a pushing block which is connected to the pushing component base body in a sliding mode, and the pushing component base body is connected to the bottom plate of the storage table in a sliding mode; the base plate is also provided with a first power mechanism for driving the pushing component base body to move, and the pushing component base body can move back and forth under the driving of the first power mechanism; the pushing part base body is also provided with a second power mechanism for driving the pushing block to move, and the pushing block can move back and forth under the driving of the second power mechanism; the pushing block is also provided with a telescopic push rod which can extend out of or retract into the pushing block, and the pushing block is also provided with a driving motor III for controlling the telescopic push rod to extend out of or retract into; the taking and placing component comprises a taking and placing component base body, the taking and placing component base body is connected to the bottom plate in a sliding mode, a third power mechanism is further arranged on the bottom plate, and the taking and placing component base body can move back and forth under the driving of the third power mechanism; a conveying channel for conveying the sample pipe rack is further arranged on the taking and placing component base body, and a conveying belt for conveying the sample pipe rack is arranged at the bottom of the conveying channel;

15. The analytical detection method according to claim 13, wherein: the sample conveying channel mechanism comprises a channel rack and a plurality of conveying channels arranged on the channel rack; the plurality of transmission channels comprise a recovery channel, and the other transmission channels are feeding channels; the sample storage mechanism is positioned at one end of the sample conveying channel mechanism, and a channel switching part is also arranged at the other end of the sample conveying channel mechanism; the channel switching component comprises a component substrate and a channel switching synchronous belt transmission mechanism arranged on the component substrate, a sliding arm is connected on the component substrate in a sliding manner, one end of the sliding arm is connected with the channel switching synchronous belt transmission mechanism, so that the sliding arm can move back and forth under the driving of the channel switching synchronous belt transmission mechanism, a U-shaped clamping groove body is also arranged at the other end of the sliding arm, the U-shaped clamping groove body is horizontally arranged, and the U-shaped opening direction of the U-shaped clamping groove body faces to the conveying channel;

in the step 2), after the sample arm finishes sampling, the method further comprises a sample tube rack recovery step, wherein the sample tube rack recovery step is to control a feeding channel to act after the sample arm finishes sampling, convey the sample tube rack which finishes sampling to a U-shaped clamping groove body of a channel switching component, then control the feeding channel to stop acting, control a sliding arm of the channel switching component to move again, drive the U-shaped clamping groove body and the sample tube rack which finishes sampling to move to a recovery channel, control the recovery channel to move the sample tube rack which finishes sampling to a taking and placing component, and control the taking and placing component to completely move the sample tube rack which finishes sampling to a sample storage mechanism to finish the recovery step.

16. The analytical detection method according to claim 13, wherein: the reagent disk mechanism comprises a shell, a rotary disk and a plurality of reagent boxes, wherein the rotary disk is rotatably arranged in the shell, the plurality of reagent boxes are arranged on the rotary disk, the rotary disk is connected with a driving motor V in a matching mode, each reagent box comprises a box body, a plurality of mutually independent reagent containing cavities I are arranged in the box body, a reagent pipe is further rotatably connected to one end of the box body, and a reagent containing cavity II is arranged in the reagent pipe; the reagent tube comprises a shell, a plurality of reagent tubes, a plurality of transmission mechanisms I, a transmission mechanism II and a driving motor VI, wherein the transmission mechanisms I are arranged on a turntable, the bottom of each reagent tube is connected with one transmission mechanism I, the transmission mechanism II and the transmission mechanism I are matched and in transmission connection, and the reagent tubes are matched and connected with the driving motor VI through the transmission mechanism I and the transmission mechanism II; the first transmission mechanism comprises an upper rotary table, a lower gear and a connecting shaft for connecting the upper rotary table and the lower gear, the upper rotary table and the lower gear are respectively positioned at two opposite sides of the rotary table, the connecting shaft penetrates through the rotary table, one end of the connecting shaft is connected with the upper rotary table, and the other end of the connecting shaft is connected with the lower gear; the transmission mechanism II comprises a bidirectional gear ring, a gear ring bearing and a driving gear II, the gear ring bearing is arranged in the shell, an outer ring of the gear ring bearing is fixedly connected to the inner bottom of the shell, an inner ring of the gear ring bearing is connected with the bidirectional gear ring, so that the bidirectional gear ring is rotatably connected to the inner bottom of the shell, a driving motor VI is further arranged in the shell, and the driving gear II is arranged on an output shaft of the driving motor VI; the driving gear II is in meshed transmission with an inner ring gear of the bidirectional gear ring, and a lower gear of each transmission mechanism I is in meshed transmission with an outer ring gear of the bidirectional gear ring, so that the transmission mechanism II is in matched transmission connection with the transmission mechanism I;

before the reagent arm sucks the reagent from the reagent disk mechanism in the step 3), controlling a driving motor V of the power mechanism IV to act so as to drive the rotary disk to rotate; at the moment, the driving motor VI does not act, and the turntable can drive a lower gear of a transmission mechanism I connected with the reagent tube to rotate along an outer ring gear of the bidirectional gear ring, so that the reagent tube automatically rotates;