CN115245534A - 一种提高记忆力并治疗失眠焦虑的中成药 - Google Patents
一种提高记忆力并治疗失眠焦虑的中成药 Download PDFInfo
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- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开的属于中药技术领域，具体为一种提高记忆力并治疗失眠焦虑的中成药，包括食用真菌粉剂和植物中药材粉剂和酶解发酵剂，称取酶解发酵剂、食用真菌粉剂、植物中药材粉剂，将称取的原料加入发酵罐中，然后再饮用水并搅拌，搅拌均匀后将发酵罐置于无菌室内酶解发酵，然后向发酵罐添加15％浓度的乙醚，然后搅拌，随后使用膜过滤机对发酵罐中的液体进行浓缩过滤，然后将浓缩后的过滤液在65℃的条件下进行喷雾干燥，食用真菌粉剂和植物中药材粉剂通过生物酶解发酵有机溶合于一体，使组方中的各生物原料干细胞在活性条件下被人体吸收利用，从而快速提高人们睡眠质量，减缓记忆力衰退，从而提高记忆力。
Description
技术领域
本发明涉及中药技术领域，具体为一种提高记忆力并治疗失眠焦虑的中成药。
背景技术
失眠是指入睡困难、睡眠质量下降和睡眠时间减少，长期失眠不但会会导致人体焦虑，还会导致记忆力和注意力的下降。失眠的干预措施主要包括药物治疗和非药物治疗，药物治疗主要以苯二氮卓类受体激动剂、抗组胺药物、艾司佐匹克隆、艾司唑仑、三环类抗抑郁药物等安眠药为主。
焦虑性失眠是由于情志不舒、气郁结滞、扰乱心神而引起的一类疾病，中医认为，多思善虑容易伤脾，进而易引发血、痰、热、食等郁结，这也是焦虑会伴发多种躯体症状等原因。中医提倡治疗与调理相结合，疏肝、益肾、健脾，宁心安神，调理气血，平衡阴阳，同时增强人体免疫力，改善人体生物节律，提高细胞活力，改善脑组织的营养状态，消除神经细胞因能量消耗而产生的功能紊乱，达到降低大脑皮层的病态兴奋性，改善睡眠，调节机体的功能的目的。
西药安眠片带有副作用的，可以引起头晕、疲乏等症状，严重时还会对肝、肾功能造成损害，且西药安眠片多数会有药物依赖，即长期服用西药安眠片后，如果停止服药就会再次失眠，而且长期服用西药安眠片后会产生抗药性，此时需要增大西药安眠片的计量才能再次起到安眠的效果。
发明内容
本发明的目的在于提供一种提高记忆力并治疗失眠焦虑的中成药，以解决上述背景技术中提出的现有的西药安眠片长期服用不但会产生抗药性还会出现药物依赖的问题。
为实现上述目的，本发明提供如下技术方案：一种提高记忆力并治疗失眠焦虑的中成药，包括食用真菌粉剂和植物中药材粉剂和酶解发酵剂，所述食用真菌粉剂按质量份数包括猴头菌8～11份、茯苓12～15份、榛蘑6～10份、金针菇3～6份、珍珠菇3～5份、雪山灵芝3～4份、黑皮鸡枞菌2～4份、平菇2～5份，所述植物中药材粉剂按质量份数包括酸枣仁8～11份、淡豆豉10～12份、栀子5～8份、桃仁6～9份、人参2～4份、肉桂3～5份、当归2～4份、大枣3～5份、甘草1～2份，称取酶解发酵剂1～3份、食用真菌粉剂40～60份、植物中药材粉剂40～60份，将称取的原料加入发酵罐中，然后再饮用水并搅拌，所述饮用水的质量与食用真菌粉剂和植物中药材粉剂质量之和的比值为2∶1，搅拌均匀后将发酵罐置于湿度为70％、温度为25℃的无菌室内酶解发酵72h，然后向发酵罐添加15％浓度的乙醚，所述乙醚的重量是饮用水重量的0.5倍，然后搅拌250min，随后使用膜过滤机对发酵罐中的液体进行浓缩过滤，然后将浓缩后的过滤液在65℃的条件下进行喷雾干燥，干燥后获得中成药半成品，使用低温粉碎机对中成药半成品进行粉碎可获得提高记忆力并治疗失眠焦虑的中成药。
优选的，所述酶解发酵剂包括纤维素酶、木聚糖酶、真菌蛋白酶、氨肽酶、过氧化酶、漆酶、多聚半乳糖醛酸酶、果胶酶、葡糖异构酶、亚硒酸钠、硫酸锌、硫酸镁、硫酸钙、氯化钾和活性干酵母，其质量之比为10∶5∶2.5∶2.5∶5∶4∶3∶2∶3∶0.1∶0.1∶1∶1∶1∶30。
优选的，所述食用真菌粉剂按质量份数包括猴头菌10份、茯苓14份、榛蘑9份、金针菇5份、珍珠菇5份、雪山灵芝4份、黑皮鸡枞菌4份、平菇4份。
优选的，所述植物中药材粉剂按质量份数包括酸枣仁10份、淡豆豉12份、栀子7份、桃仁7份、人参2份、肉桂3份、当归3份、大枣5份、甘草1份。
优选的，所述食用真菌粉剂和植物中药材粉剂的粒径为0.8～1mm，所述提高记忆力并治疗失眠焦虑的中成药的粒径为50～120um。
优选的，所述发酵罐中的液体在发酵时，所述发酵罐中的液体温度保持在34～36℃。
优选的，所述食用真菌粉剂和植物中药材粉剂在制备时，首先对原料进行清洗，清洗完毕后将其荫干，然后使用植物粉碎机将其粉碎可以获得食用真菌粉剂和植物中药材粉剂，随后将食用真菌粉剂和植物中药材粉剂分别打包备用。
与现有技术相比，本发明的有益效果是：
1)食用真菌粉剂和植物中药材粉剂通过生物酶解发酵有机溶合于一体，使组方中的各生物原料干细胞在活性条件下被人体吸收利用，从而快速提高人们睡眠质量，减缓记忆力衰退，从而提高记忆力；
2)本产品原料的选择均为中华人民共和国药食同源目录中规定的既可食用又可药用的中药材，其无毒无害、安全可靠，本产品以食用真菌粉剂中的各种真菌多糖相互组合来提高人体免疫系统为基础，然后以植物中药材粉剂的活体干细胞之精华对失眠焦虑进行治疗，通过提高免疫力来使人体自动恢复可以避免人体产生药物依赖，同时真菌粉剂和植物中药材粉剂中的多种中药材和真菌相互混合，可以避免人体对单一药材产生抗药性。
附图说明
图1为本发明生产流程示意图。
具体实施方式
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
在本发明的描述中，需要理解的是，术语“上”、“下”、“前”、“后”、“左”、“右”、“顶”、“底”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。
在本发明的描述中，需要说明的是，除非另有明确的规定和限定，术语“安装”、“设置有”、“套设/接”、“连接”等，应做广义理解，例如“连接”，可以是固定连接，也可以是可拆卸连接，或一体地连接；可以是机械连接，也可以是电连接；可以是直接相连，也可以通过中间媒介间接相连，可以是两个元件内部的连通。对于本领域的普通技术人员而言，可以具体情况理解上述术语在本发明中的具体含义。
实施例：
请参阅图1，本发明提供一种技术方案：一种提高记忆力并治疗失眠焦虑的中成药，包括食用真菌粉剂和植物中药材粉剂和酶解发酵剂，其特征在于：食用真菌粉剂按质量份数包括猴头菌8～11份、茯苓12～15份、榛蘑6～10份、金针菇3～6份、珍珠菇3～5份、雪山灵芝3～4份、黑皮鸡枞菌2～4份、平菇2～5份；
猴头菌具有健脾养胃、安神、抗癌的功效，对体虚乏力、消化不良、失眠、胃与十二指肠溃疡、慢性胃炎、消化道肿瘤等症均有特效；
茯苓，《本草正》曰：能利窍去湿，利窍则开心益智，导浊生津，去湿则逐水燥脾，补中健胃，袪惊痫，厚肠脏，治痰之本，宁心安神；
榛蘑具有祛风活络、强筋壮骨的作用，用于治疗腰腿疼痛、佝偻病、癫痫、头痛头晕、神经衰弱；
金针菇中含有金针菇多糖，通过金针菇多糖治疗记忆障碍模型小鼠，发现金针菇多糖能有效改善障碍小鼠的学习记忆能力，因此，金针菇具有增强学习记忆能力；
珍珠菇菌伞表面的粘性物质是一种核酸，其对保持人体的精力和脑力大有益处；
平菇中含有大量蛋白质和氨基酸等能促进智力发育的有效成分，对婴儿和老人健康十分重要；
植物中药材粉剂按质量份数包括酸枣仁8～11份、淡豆豉10～12份、栀子5～8份、桃仁6～9份、人参2～4份、肉桂3～5份、当归2～4份、大枣3～5份、甘草1～2份；
酸枣仁具具有养心补肝、宁心安神、敛汗、生津之功效，常用于虚烦不眠、惊悸多梦、体虚多汗、津伤口渴；
淡豆豉为豆科植物大豆的成熟种子的发酵加工品，其性味苦寒，具有解表、除烦、宣郁、解毒之功效，用于伤寒热病、寒热、头痛、烦躁、胸闷；
人参归脾、肺经、心经，有补气、固脱、生津、安神、益智的功效，其为著名强壮滋补药，适用于调整血压、恢复心脏功能、神经衰弱及身体虚弱等症；
称取酶解发酵剂1～3份、食用真菌粉剂40～60份、植物中药材粉剂40～60份，将称取的原料加入发酵罐中，然后再饮用水并搅拌，饮用水的质量与食用真菌粉剂和植物中药材粉剂质量之和的比值为2∶1，搅拌均匀后将发酵罐置于湿度为70％、温度为25℃的无菌室内酶解发酵72h，然后向发酵罐添加15％浓度的乙醚，乙醚的重量是饮用水重量的0.5倍，然后搅拌250min，随后使用膜过滤机对发酵罐中的液体进行浓缩过滤，然后将浓缩后的过滤液在65℃的条件下进行喷雾干燥，干燥后获得中成药半成品，使用低温粉碎机对中成药半成品进行粉碎可获得提高记忆力并治疗失眠焦虑的中成药。
酶解发酵剂包括纤维素酶、木聚糖酶、真菌蛋白酶、氨肽酶、过氧化酶、漆酶、多聚半乳糖醛酸酶、果胶酶、葡糖异构酶、亚硒酸钠、硫酸锌、硫酸镁、硫酸钙、氯化钾和活性干酵母，其质量之比为10∶5∶2.5∶2.5∶5∶4∶3∶2∶3∶0.1∶0.1∶1∶1∶1∶30，纤维素酶、木聚糖酶、真菌蛋白酶、氨肽酶、过氧化酶、漆酶、多聚半乳糖醛酸酶、果胶酶、葡糖异构酶、亚硒酸钠、硫酸锌、硫酸镁、硫酸钙、氯化钾和活性干酵母混合均匀后可获得酶解发酵剂，制成的酶解发酵剂打包后放置在0～4℃的条件保存备用。
食用真菌粉剂按质量份数包括猴头菌10份、茯苓14份、榛蘑9份、金针菇5份、珍珠菇5份、雪山灵芝4份、黑皮鸡枞菌4份、平菇4份。
植物中药材粉剂按质量份数包括酸枣仁10份、淡豆豉12份、栀子7份、桃仁7份、人参2份、肉桂3份、当归3份、大枣5份、甘草1份。
食用真菌粉剂和植物中药材粉剂的粒径为0.8～1mm，提高记忆力并治疗失眠焦虑的中成药的粒径为50～120um。
发酵罐中的液体在发酵时，发酵罐中的液体温度保持在34～36℃，发酵时，发酵罐中液体的温度会逐渐上升，当温度高于35℃时，可以通过搅拌降低其温度，正常情况下8小时搅拌一次，每天搅拌三次即可。
食用真菌粉剂和植物中药材粉剂在制备时，首先对原料进行清洗，清洗完毕后将其荫干，然后使用植物粉碎机将其粉碎可以获得食用真菌粉剂和植物中药材粉剂，随后将食用真菌粉剂和植物中药材粉剂分别打包备用。
以上显示和描述了本发明的基本原理和主要特征和本发明的优点，对于本领域技术人员而言，显然本发明不限于上述示范性实施例的细节，而且在不背离本发明的精神或基本特征的情况下，能够以其他的具体形式实现本发明；因此，无论从哪一点来看，均应将实施例看作是示范性的，而且是非限制性的，本发明的范围由所附权利要求而不是上述说明限定，因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本发明内，不应将权利要求中的任何附图标记视为限制所涉及的权利要求。
尽管已经示出和描述了本发明的实施例，对于本领域的普通技术人员而言，可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型，本发明的范围由所附权利要求及其等同物限定。
Claims (7)
1.一种提高记忆力并治疗失眠焦虑的中成药，包括食用真菌粉剂和植物中药材粉剂和酶解发酵剂，其特征在于：所述食用真菌粉剂按质量份数包括猴头菌8～11份、茯苓12～15份、榛蘑6～10份、金针菇3～6份、珍珠菇3～5份、雪山灵芝3～4份、黑皮鸡枞菌2～4份、平菇2～5份，所述植物中药材粉剂按质量份数包括酸枣仁8～11份、淡豆豉10～12份、栀子5～8份、桃仁6～9份、人参2～4份、肉桂3～5份、当归2～4份、大枣3～5份、甘草1～2份，称取酶解发酵剂1～3份、食用真菌粉剂40～60份、植物中药材粉剂40～60份，将称取的原料加入发酵罐中，然后再饮用水并搅拌，所述饮用水的质量与食用真菌粉剂和植物中药材粉剂质量之和的比值为2∶1，搅拌均匀后将发酵罐置于湿度为70％、温度为25℃的无菌室内酶解发酵72h，然后向发酵罐添加15％浓度的乙醚，所述乙醚的重量是饮用水重量的0.5倍，然后搅拌250min，随后使用膜过滤机对发酵罐中的液体进行浓缩过滤，然后将浓缩后的过滤液在65℃的条件下进行喷雾干燥，干燥后获得中成药半成品，使用低温粉碎机对中成药半成品进行粉碎可获得提高记忆力并治疗失眠焦虑的中成药。
2.根据权利要求1所述的一种提高记忆力并治疗失眠焦虑的中成药，其特征在于：所述酶解发酵剂包括纤维素酶、木聚糖酶、真菌蛋白酶、氨肽酶、过氧化酶、漆酶、多聚半乳糖醛酸酶、果胶酶、葡糖异构酶、亚硒酸钠、硫酸锌、硫酸镁、硫酸钙、氯化钾和活性干酵母，其质量之比为10∶5∶2.5∶2.5∶5∶4∶3∶2∶3∶0.1∶0.1∶1∶1∶1∶30。
3.根据权利要求1所述的一种提高记忆力并治疗失眠焦虑的中成药，其特征在于：所述食用真菌粉剂按质量份数包括猴头菌10份、茯苓14份、榛蘑9份、金针菇5份、珍珠菇5份、雪山灵芝4份、黑皮鸡枞菌4份、平菇4份。
4.根据权利要求1所述的一种提高记忆力并治疗失眠焦虑的中成药，其特征在于：所述植物中药材粉剂按质量份数包括酸枣仁10份、淡豆豉12份、栀子7份、桃仁7份、人参2份、肉桂3份、当归3份、大枣5份、甘草1份。
5.根据权利要求1所述的一种提高记忆力并治疗失眠焦虑的中成药，其特征在于：所述食用真菌粉剂和植物中药材粉剂的粒径为0.8～1mm，所述提高记忆力并治疗失眠焦虑的中成药的粒径为50～120um。
6.根据权利要求1所述的一种提高记忆力并治疗失眠焦虑的中成药，其特征在于：所述发酵罐中的液体在发酵时，所述发酵罐中的液体温度保持在34～36℃。
7.根据权利要求1所述的一种提高记忆力并治疗失眠焦虑的中成药，其特征在于：所述食用真菌粉剂和植物中药材粉剂在制备时，首先对原料进行清洗，清洗完毕后将其荫干，然后使用植物粉碎机将其粉碎可以获得食用真菌粉剂和植物中药材粉剂，随后将食用真菌粉剂和植物中药材粉剂分别打包备用。
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