CN115151819A - 检测和/或定量多个生物液体样品中的感兴趣的分析物的方法 - Google Patents

检测和/或定量多个生物液体样品中的感兴趣的分析物的方法 Download PDF

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Publication number
CN115151819A
CN115151819A CN202080096609.7A CN202080096609A CN115151819A CN 115151819 A CN115151819 A CN 115151819A CN 202080096609 A CN202080096609 A CN 202080096609A CN 115151819 A CN115151819 A CN 115151819A
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analyte
microparticles
interest
sample
subset
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Chinese (zh)
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云根·恩尔曼川特
凯瑟琳·斯蒂尔莫茨
斯蒂芬·胡博得
托马斯·艾林戈
奥利沃·莱姆茨
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Brink Co
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Brink Co
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
CN202080096609.7A 2019-12-16 2020-12-15 检测和/或定量多个生物液体样品中的感兴趣的分析物的方法 Pending CN115151819A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19216592.6 2019-12-16
EP19216592.6A EP3839508A1 (en) 2019-12-16 2019-12-16 A method of detecting and/or quantitating an analyte of interest in a plurality of biological liquid samples
PCT/EP2020/086194 WO2021122579A1 (en) 2019-12-16 2020-12-15 A method of detecting and/or quantitating an analyte of interest in a plurality of biological liquid samples

Publications (1)

Publication Number Publication Date
CN115151819A true CN115151819A (zh) 2022-10-04

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CN202080096609.7A Pending CN115151819A (zh) 2019-12-16 2020-12-15 检测和/或定量多个生物液体样品中的感兴趣的分析物的方法

Country Status (13)

Country Link
US (1) US20230063987A1 (https=)
EP (2) EP3839508A1 (https=)
JP (1) JP2023506261A (https=)
KR (1) KR20220114630A (https=)
CN (1) CN115151819A (https=)
AU (1) AU2020403853A1 (https=)
BR (1) BR112022011676A2 (https=)
CA (1) CA3161939A1 (https=)
DK (1) DK4078181T3 (https=)
ES (1) ES2980821T3 (https=)
FI (1) FI4078181T3 (https=)
IL (1) IL293851B2 (https=)
WO (1) WO2021122579A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024260204A1 (zh) * 2023-06-22 2024-12-26 台湾创新材料股份有限公司 一种微液滴产生装置和方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022205377A1 (en) 2021-01-08 2023-07-20 Cellanome, Inc. Devices and methods for analyzing biological samples
WO2022150659A1 (en) * 2021-01-08 2022-07-14 Cellanome, Inc. Devices and methods for analyzing biological samples
US12576400B2 (en) 2021-01-08 2026-03-17 Cellanome, Inc. Methods for incubating and analyzing a cell in a compartment of a fluidic device
EP4177352A1 (en) 2021-11-05 2023-05-10 Blink AG A microsphere comprising a first material and a second material
EP4252907A1 (en) 2022-03-30 2023-10-04 Blink AG A method for arranging microspheres in a non-aqueous liquid phase
EP4438737A1 (en) * 2023-03-31 2024-10-02 Blink AG A method of quantifying a concentration of an analyte in a sample

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1470873A (zh) * 2002-07-22 2004-01-28 � 赵 Dna固相扩增与流式检测分析技术与试剂盒
WO2009048530A2 (en) * 2007-10-05 2009-04-16 Panomics, Inc. Highly multiplexed particle-based assays
WO2015073999A1 (en) * 2013-11-18 2015-05-21 Integenx Inc. Cartridges and instruments for sample analysis
WO2018122162A1 (en) * 2016-12-30 2018-07-05 Blink Ag A prefabricated microparticle for performing a detection of an analyte

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1470873A (zh) * 2002-07-22 2004-01-28 � 赵 Dna固相扩增与流式检测分析技术与试剂盒
WO2009048530A2 (en) * 2007-10-05 2009-04-16 Panomics, Inc. Highly multiplexed particle-based assays
WO2015073999A1 (en) * 2013-11-18 2015-05-21 Integenx Inc. Cartridges and instruments for sample analysis
WO2018122162A1 (en) * 2016-12-30 2018-07-05 Blink Ag A prefabricated microparticle for performing a detection of an analyte

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024260204A1 (zh) * 2023-06-22 2024-12-26 台湾创新材料股份有限公司 一种微液滴产生装置和方法

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Publication number Publication date
FI4078181T3 (fi) 2024-05-07
EP4078181A1 (en) 2022-10-26
WO2021122579A1 (en) 2021-06-24
BR112022011676A2 (pt) 2022-10-11
ES2980821T3 (es) 2024-10-03
EP4078181B1 (en) 2024-03-20
US20230063987A1 (en) 2023-03-02
IL293851A (en) 2022-08-01
JP2023506261A (ja) 2023-02-15
IL293851B2 (en) 2024-03-01
CA3161939A1 (en) 2022-06-14
KR20220114630A (ko) 2022-08-17
EP3839508A1 (en) 2021-06-23
DK4078181T3 (da) 2024-05-13
IL293851B1 (en) 2023-11-01
AU2020403853A1 (en) 2022-07-07

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