CN1151318A - Traditional Chinese medicinal preparation for treatment of tetanus - Google Patents
Traditional Chinese medicinal preparation for treatment of tetanus Download PDFInfo
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- CN1151318A CN1151318A CN 96119436 CN96119436A CN1151318A CN 1151318 A CN1151318 A CN 1151318A CN 96119436 CN96119436 CN 96119436 CN 96119436 A CN96119436 A CN 96119436A CN 1151318 A CN1151318 A CN 1151318A
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- tetanus
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Abstract
A Chinese-medicinal medication for curing tetanus of mankind or animals is prepared from 11 Chinese-medicinal materials such as gastrodia tuber, ledebouriella root, honeysuckle flower, chaenomeles fruit, earthworm, etc. and features high curative rate up to 95% or more, quick action and less by-effect.
Description
The present invention relates to a kind of Chinese medicine preparation, the tetanic Chinese medicine preparation of particularly a kind of treatment.
Tetanus is to invade body by clostridium tetani, breeding, a kind of strong extracellular toxin of secretion---sphaceltoxin and cause with muscle clonospasm and tonic contraction to be the serious specific infection of feature.This disease mortality rate is higher, average about 30%, neonate Ke Da 70%.Sickness rate such as complication that this is sick such as respiratory failure, circulatory failure and pulmonary infection are also higher, can reach about 70%.It is that paroxysmal is twitched that tetanus threatens the risk factor of people's life, particularly the spasm of respiratory muscle and larynx.At present should disease still higher at the relatively poor geographic sickness rate of sanitary condition.In war wound infected, tetanus was a kind of disease of serious threat wounded life.At present, medical circle does not still have the specific treatment method both at home and abroad.Comprehensive treatments such as that doctor trained in Western medicine all adopts is antitoxin, infection, relieving convulsion, calmness, reinforcement nutrition and nursing.Aspect antitoxin, mainly use antitetanic serum (TAT), but TAT can only in and blood and the free tetanus toxin of brain chi chung because there are powerful affinity in tetanus toxin and nervous tissue, in case the combination just can not be neutralized by TAT.Use TAT treatment tetanus many families on the consumption usage at present and have different opinions, nothing concerns that certainly this fact is generally accepted but TAT consumption and patient live or die.Previously used the patient of TAT, and did its positive rate of hypersensitive test again and obviously improve, have in addition general reaction can take place.Aspect infection, adopt penicillin and metronidazole etc., to suppress breeding, control infection and the complication prevention of clostridium tetani more.Using types of drugs more aspect the relieving convulsion calmness in the past, as stable, chlorpromazine, sodium phenobarbital, chloral hydrate etc., be recognized that both at home and abroad at present: " stabilization " intravenously administrable, stabile consumption surpasses conventional several times, in order to calm convulsion, because stabile safety coefficient is bigger, and there is blocking-up tetanus extracellular toxin can reduce oxygen consumption again to neural effect.But comprise the general tranquilizer of stabilizing, Chang Buneng controls serious persistence effectively and twitches, need use thiopentone and muscle relaxant again, but the side effect that all influential respiratory function of these medicines and inhibition are breathed, improper use can cause paralysis of respiratory muscle and suffocate.Muscle relaxant can also cause that gastrointestinal smoulders and the serious cardiovascular dysfunction.Use tracheal intubation and respirator, can cause respiratory secretions to increase again and merge pulmonary infection.Tracheotomy is one of tetanic important measures of rescue, but still has unified not accusing of so far, and the frequent expectorant of inhaling of the wound of tracheotomy and incision back easily causes twitch generation and respiratory infections.Still can cause respiratory failure death every muscular spasm after the tracheotomy because of rib.Nasal feeding is to keep one of important measures of nutrition at present, but also can cause laryngospasm, scorching around the laryngeal cartilages, complication such as cough does not freely cause suffocating.The traditional Chinese medical science to tetanic understanding relatively early just clearly proposes " tetanus " this name of disease far away from the Tang Dynasty, thinks brokenly to hinder in the part in ailment said due to cold or exposure, and is in full accord to the tetanus disease of the description of symptom and modern medicine.Aspect treatment with dispel the wind, detoxifcation, relieving spasm by subduing liver-wind, eliminate the phlegm, the tranquillizing and allaying excitement pending trial because of and dialectical opinion to control be guideline, the side's of sending medication kind more than 100, representative prescription commonly used chase after wind soup etc. as Yuzhen San, five tigers, but curative effect is all not as people's will.Some units adopt combination of Chinese and Western medicine method treatment tetanus at present, obviously reduced mortality rate, but cure rate are still undesirable.
The purpose of this invention is to provide the tetanic Chinese medicine preparation of a kind of treatment, this preparation cure rate height, side effect is little, and effect is rapidly.
The object of the present invention is achieved like this: prescription comprises following component and weight portion ratio:
Rhizoma Gastrodiae 9-50 Radix Saposhnikoviae 9-30
Flos Lonicerae 9-50 Fructus Chaenomelis 9-50
Pheretima 3-15 Radix Glycyrrhizae 6-15
Scolopendra 3-10 Herba Ephedrae 1-15
Scorpio 1-6 Bombyx Batryticatus 1-10
Periostracum Cicadae 1-15
Above-mentioned prescription also can add following at least a component and weight portion:
Agkistrodon 3-15 Radix Puerariae 9-30
Fructus Mume 9-30 Rhizoma Belamcandae 9-30
Radix Paeoniae Alba 9-30 Concretio silicea Bambusae seu schizostachyi 9-30
Gypsum Fibrosum 20-60
Above-mentioned each component is carried out conventional water extraction, concentrate, make mixture, pill; Also can pass through conventional water extraction, after concentrating, make granule by conventional alcohol precipitation process; Can also extract through conventional many solvents and make oral liquid or injection.
Advantage of the present invention is: the cure rate height, can reach more than 95%, side effect is little, this preparation has the merit of the expectorant of dispeling the wind, heat-clearing and toxic substances removing, relieving spasm by subduing liver-wind, tranquillizing and allaying excitement, take effect rapidly, potion can be removed the tic symptom, removes life danger, also can be used for the tetanus treatment of animals such as pig, cattle, horse, sheep.
Provide embodiment below:
The component and the weight portion of embodiment 1 prescription are as follows:
Rhizoma Gastrodiae 10 Radix Saposhnikoviaes 9
Flos Lonicerae 10 Fructus Chaenomeliss 10
Pheretima 3 Radix Glycyrrhizae 6
Scolopendra 3 Herba Ephedraes 1
Scorpio 1 Bombyx Batryticatus 3
Periostracum Cicadae 3
After ratio takes by weighing by weight with above-mentioned each component, carry out conventional water extraction, concentrate, adding preservative agent is made mixture.
The component and the weight portion of embodiment 2 prescriptions are as follows;
Rhizoma Gastrodiae 50 Radix Saposhnikoviaes 30
Flos Lonicerae 50 Fructus Chaenomeliss 50
Pheretima 15 Radix Glycyrrhizae 15
Scolopendra 10 Herba Ephedraes 10
Scorpio 6 Bombyx Batryticatus 10
Periostracum Cicadae 15
After ratio takes by weighing by weight with above-mentioned each component, carry out conventional water extraction, concentrate, add excipient and make tablet.
The component and the weight portion of embodiment 3 prescriptions are as follows;
Rhizoma Gastrodiae 15 Radix Saposhnikoviaes 15
Flos Lonicerae 15 Fructus Chaenomeliss 15
Pheretima 10 Radix Glycyrrhizae 9
Scolopendra 6 Herba Ephedraes 3
Scorpio 2 Bombyx Batryticatus 5
Periostracum Cicadae 6 Agkistrodons 6
After ratio takes by weighing by weight with above-mentioned each component, carry out conventional water extraction, concentrate, add excipient and make pill (watered pill or honeyed pill).
The component and the weight portion of embodiment 4 prescriptions are as follows;
Rhizoma Gastrodiae 15 Radix Saposhnikoviaes 15
Flos Lonicerae 15 Fructus Chaenomeliss 15
Pheretima 10 Radix Glycyrrhizae 9
Scolopendra 6 Herba Ephedraes 5
Scorpio 2 Bombyx Batryticatus 5
Periostracum Cicadae 10 Radix Puerariaes 15
After ratio takes by weighing by weight with above-mentioned each component, carry out conventional water extraction, concentrate, precipitate with ethanol, water precipitating are made oral liquid.
The component and the weight portion of embodiment 5 prescriptions are as follows:
Rhizoma Gastrodiae 20 Radix Saposhnikoviaes 15
Flos Lonicerae 20 Fructus Chaenomeliss 20
Pheretima 10 Radix Glycyrrhizae 9
Scolopendra 10 Herba Ephedraes 5
Scorpio 3 Bombyx Batryticatus 5
Periostracum Cicadae 10 Fructus Mumes 15
After ratio takes by weighing by weight with above-mentioned each component, carry out conventional water extraction, alcohol reflux, make injection.
The component and the weight portion of embodiment 6 prescriptions are as follows:
Rhizoma Gastrodiae 30 Radix Saposhnikoviaes 30
Flos Lonicerae 30 Fructus Chaenomeliss 30
Pheretima 15 Radix Glycyrrhizae 15
Scolopendra 10 Herba Ephedraes 10
Scorpio 4 Bombyx Batryticatus 10
Periostracum Cicadae 15 Rhizoma Belamcandae 25
After ratio takes by weighing by weight with above-mentioned each component, carry out conventional water extraction, precipitate with ethanol, ether extraction, make injection.
The component and the weight portion of embodiment 7 prescriptions are as follows:
Rhizoma Gastrodiae 40 Radix Saposhnikoviaes 30
Flos Lonicerae 40 Fructus Chaenomeliss 40
Pheretima 15 Radix Glycyrrhizae 15
Scolopendra 10 Herba Ephedraes 10
Scorpio 6 Bombyx Batryticatus 10
Periostracum Cicadae 15 Radix Paeoniae Albas 30
Plant amedica in the prescription is carried out water extraction, precipitate with ethanol; Animal drugs water extraction, concentrated is made granule according to a conventional method.
The component and the weight portion of embodiment 8 prescriptions are as follows:
Rhizoma Gastrodiae 10 Radix Saposhnikoviaes 9
Flos Lonicerae 10 Fructus Chaenomeliss 9
Pheretima 3 Radix Glycyrrhizae 6
Scolopendra 3 Herba Ephedraes 1
Scorpio 1 Bombyx Batryticatus 3
Periostracum Cicadae 3 Concretio silicea Bambusae seu schizostachyis 9
To fill a prescription and carry out water extraction according to a conventional method, precipitate with ethanol, water precipitating are made oral liquid.
The component and the weight portion of embodiment 9 prescriptions are as follows:
Rhizoma Gastrodiae 20 Radix Saposhnikoviaes 15
Flos Lonicerae 20 Fructus Chaenomeliss 20
Pheretima 10 Radix Glycyrrhizae 9
Scolopendra 10 Herba Ephedraes 5
Scorpio 3 Bombyx Batryticatus 5
Periostracum Cicadae 10 Gypsum Fibrosum 50
Above-mentioned each component is taken by weighing by weight, carry out water extraction according to a conventional method, concentrated, precipitate with ethanol is made oral liquid.
Claims (2)
1, the tetanic Chinese medicine preparation of a kind of treatment is characterized in that: prescription comprises following component and weight portion:
Rhizoma Gastrodiae 9-50 Radix Saposhnikoviae 9-30
Flos Lonicerae 9-50 Fructus Chaenomelis 9-50
Pheretima 3-15 Radix Glycyrrhizae 6-15
Scolopendra 3-10 Herba Ephedrae 1-15
Scorpio 1-6 Bombyx Batryticatus 1-10
Periostracum Cicadae 1-15.
2, Chinese medicine preparation according to claim 1 is characterized in that: can add following at least a component and weight portion in the prescription:
Agkistrodon 3-15 Radix Puerariae 9-30
Fructus Mume 9-30 Rhizoma Belamcandae 9-30
Radix Paeoniae Alba 9-30 Concretio silicea Bambusae seu schizostachyi 9-30
Gypsum Fibrosum 20-60.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96119436 CN1151318A (en) | 1996-09-25 | 1996-09-25 | Traditional Chinese medicinal preparation for treatment of tetanus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96119436 CN1151318A (en) | 1996-09-25 | 1996-09-25 | Traditional Chinese medicinal preparation for treatment of tetanus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1151318A true CN1151318A (en) | 1997-06-11 |
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ID=5125695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 96119436 Pending CN1151318A (en) | 1996-09-25 | 1996-09-25 | Traditional Chinese medicinal preparation for treatment of tetanus |
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| CN (1) | CN1151318A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181534B (en) * | 2007-12-04 | 2010-07-21 | 张丽 | Traditional Chinese medicine preparation for curing tetanus |
| CN102247409A (en) * | 2011-08-18 | 2011-11-23 | 潘万领 | Traditional Chinese medicine for treating acne and preparation method thereof |
| CN102526393A (en) * | 2012-01-16 | 2012-07-04 | 崔永奎 | Traditional Chinese medicine for treating tetanus |
| CN103272121A (en) * | 2013-06-07 | 2013-09-04 | 刘建飞 | Tetanus treatment traditional Chinese medicine preparation |
| CN104784360A (en) * | 2015-03-31 | 2015-07-22 | 赵忠莲 | Traditional Chinese medicine preparation for preventing tetanus |
| CN107715109A (en) * | 2017-10-20 | 2018-02-23 | 马玉珍 | Traditional Chinese and western medicine for lockjaw disease treatment combines medicine and its application |
| CN109966424A (en) * | 2019-03-26 | 2019-07-05 | 内蒙古艾鲁维农牧业开发有限责任公司 | A kind of Chinese materia medica preparation for tetanus treatment initial stage |
-
1996
- 1996-09-25 CN CN 96119436 patent/CN1151318A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181534B (en) * | 2007-12-04 | 2010-07-21 | 张丽 | Traditional Chinese medicine preparation for curing tetanus |
| CN102247409A (en) * | 2011-08-18 | 2011-11-23 | 潘万领 | Traditional Chinese medicine for treating acne and preparation method thereof |
| CN102526393A (en) * | 2012-01-16 | 2012-07-04 | 崔永奎 | Traditional Chinese medicine for treating tetanus |
| CN102526393B (en) * | 2012-01-16 | 2013-09-04 | 崔永奎 | Traditional Chinese medicine for treating tetanus |
| CN103272121A (en) * | 2013-06-07 | 2013-09-04 | 刘建飞 | Tetanus treatment traditional Chinese medicine preparation |
| CN104784360A (en) * | 2015-03-31 | 2015-07-22 | 赵忠莲 | Traditional Chinese medicine preparation for preventing tetanus |
| CN107715109A (en) * | 2017-10-20 | 2018-02-23 | 马玉珍 | Traditional Chinese and western medicine for lockjaw disease treatment combines medicine and its application |
| CN109966424A (en) * | 2019-03-26 | 2019-07-05 | 内蒙古艾鲁维农牧业开发有限责任公司 | A kind of Chinese materia medica preparation for tetanus treatment initial stage |
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