CN115087866A - 液相色谱仪 - Google Patents

液相色谱仪 Download PDF

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Publication number
CN115087866A
CN115087866A CN202080096485.2A CN202080096485A CN115087866A CN 115087866 A CN115087866 A CN 115087866A CN 202080096485 A CN202080096485 A CN 202080096485A CN 115087866 A CN115087866 A CN 115087866A
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CN
China
Prior art keywords
port
column
flow path
sample
chip
Prior art date
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Pending
Application number
CN202080096485.2A
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English (en)
Chinese (zh)
Inventor
凑浩之
安藤翔太郎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shimadzu Corp
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Shimadzu Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Shimadzu Corp filed Critical Shimadzu Corp
Publication of CN115087866A publication Critical patent/CN115087866A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N37/00—Details not covered by any other group of this subclass
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N2030/382—Flow patterns flow switching in a single column
    • G01N2030/385—Flow patterns flow switching in a single column by switching valves

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
CN202080096485.2A 2020-02-21 2020-02-21 液相色谱仪 Pending CN115087866A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2020/007254 WO2021166265A1 (ja) 2020-02-21 2020-02-21 液体クロマトグラフ

Publications (1)

Publication Number Publication Date
CN115087866A true CN115087866A (zh) 2022-09-20

Family

ID=77391543

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080096485.2A Pending CN115087866A (zh) 2020-02-21 2020-02-21 液相色谱仪

Country Status (4)

Country Link
US (1) US12360088B2 (https=)
JP (1) JP7334845B2 (https=)
CN (1) CN115087866A (https=)
WO (1) WO2021166265A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116448931A (zh) * 2023-04-12 2023-07-18 西北工业大学 一种液相色谱阵列柱芯片及其制备方法和应用

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US20100307334A1 (en) * 2009-06-09 2010-12-09 National Taiwan University Of Science And Technology Fluid separation method and fluid separation apparatus
US20120024399A1 (en) * 2009-03-06 2012-02-02 Waters Technologies Corporation Electrospray Interface To A Microfluidic Substrate
JP2013200231A (ja) * 2012-03-26 2013-10-03 Toppan Printing Co Ltd 複数の流路を持つクロマトグラフ分析装置
JP2017116350A (ja) * 2015-12-22 2017-06-29 株式会社島津製作所 流路機構及びこれを備えた液体クロマトグラフ
JP2018169350A (ja) * 2017-03-30 2018-11-01 株式会社島津製作所 液体クロマトグラフ
CN209858493U (zh) * 2019-04-25 2019-12-27 天津出入境检验检疫局动植物与食品检测中心 一种双通道在线分析前处理和离线分析一体液相色谱仪

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JPH01235849A (ja) * 1988-03-15 1989-09-20 Shimadzu Corp 分取液体クロマトグラフ
US5958227A (en) * 1997-07-15 1999-09-28 Tosoh Corporation Liquid chromatograph apparatus with a switching valve
US6136272A (en) * 1997-09-26 2000-10-24 University Of Washington Device for rapidly joining and splitting fluid layers
WO2000045929A1 (en) * 1999-02-08 2000-08-10 Admetric Biochem Inc. Chromatographic system with pre-detector eluent switching
ATE419911T1 (de) * 1999-04-23 2009-01-15 Advion Biosystems Inc Parallel ausgeführte flüssigkeitschromatographievorrichtung mit hohem durchsatz
JP2001235849A (ja) * 2000-02-24 2001-08-31 Shin Etsu Chem Co Ltd 位相シフトマスク及びその製造方法
US7691645B2 (en) * 2001-01-09 2010-04-06 Agilent Technologies, Inc. Immunosubtraction method
WO2004015411A1 (en) * 2002-08-08 2004-02-19 Nanostream, Inc. Systems and methods for high-throughput microfluidic sample analysis
JP3816883B2 (ja) * 2003-03-06 2006-08-30 株式会社日立ハイテクノロジーズ 液体クロマトグラフ質量分析装置
JP3823092B2 (ja) * 2003-03-11 2006-09-20 株式会社日立ハイテクノロジーズ 分離分析装置
WO2005079944A1 (en) 2004-02-17 2005-09-01 California Institute Of Technology On-chip temperature controlled liquid chromatography methods and devices
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WO2008073535A2 (en) * 2006-08-12 2008-06-19 Van Pelt Colleen K Nanoliter flow rate separation and electrospray device with plug and play high pressure connections and multi-sensor diagnostic monitoring system
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JP5081473B2 (ja) * 2007-02-28 2012-11-28 株式会社日立ハイテクノロジーズ 液体クロマトグラフ及び分離カラム
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US10092858B2 (en) * 2012-05-25 2018-10-09 Thermo Electron Manufacturing Limited Method and apparatus for improved resolution chromatography
US20160018365A1 (en) * 2014-06-13 2016-01-21 Masoud Agah Functionalized Metal Oxides As A Stationary Phase And A Surface Template For Micro Gas Chromatography Separation Columns
US10488375B2 (en) * 2017-06-02 2019-11-26 Venica Fluid Sciences Limited System for detecting liquid analytes
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Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070071638A1 (en) * 2004-05-22 2007-03-29 Karsten Kraiczek Parallel processing microfluidic chip
US20120024399A1 (en) * 2009-03-06 2012-02-02 Waters Technologies Corporation Electrospray Interface To A Microfluidic Substrate
US20100307334A1 (en) * 2009-06-09 2010-12-09 National Taiwan University Of Science And Technology Fluid separation method and fluid separation apparatus
JP2013200231A (ja) * 2012-03-26 2013-10-03 Toppan Printing Co Ltd 複数の流路を持つクロマトグラフ分析装置
JP2017116350A (ja) * 2015-12-22 2017-06-29 株式会社島津製作所 流路機構及びこれを備えた液体クロマトグラフ
JP2018169350A (ja) * 2017-03-30 2018-11-01 株式会社島津製作所 液体クロマトグラフ
CN209858493U (zh) * 2019-04-25 2019-12-27 天津出入境检验检疫局动植物与食品检测中心 一种双通道在线分析前处理和离线分析一体液相色谱仪

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116448931A (zh) * 2023-04-12 2023-07-18 西北工业大学 一种液相色谱阵列柱芯片及其制备方法和应用

Also Published As

Publication number Publication date
JPWO2021166265A1 (https=) 2021-08-26
US20230104759A1 (en) 2023-04-06
US12360088B2 (en) 2025-07-15
JP7334845B2 (ja) 2023-08-29
WO2021166265A1 (ja) 2021-08-26

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