CN115054564A - Composite small-molecule active peptide whitening secondary polishing essence - Google Patents
Composite small-molecule active peptide whitening secondary polishing essence Download PDFInfo
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- CN115054564A CN115054564A CN202111143053.5A CN202111143053A CN115054564A CN 115054564 A CN115054564 A CN 115054564A CN 202111143053 A CN202111143053 A CN 202111143053A CN 115054564 A CN115054564 A CN 115054564A
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- extract
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- active peptide
- small
- whitening
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- 229930182817 methionine Natural products 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 1
- 239000012982 microporous membrane Substances 0.000 description 1
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- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229960005323 phenoxyethanol Drugs 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 235000005412 red sage Nutrition 0.000 description 1
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- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
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Abstract
The invention relates to a composite small-molecule active peptide whitening secondary polishing essence which contains raw materials such as a composite small-molecule active peptide, an improved Taohong Siwu decoction extract, a rhodiola rosea extract, a ginseng extract, nicotinamide, arbutin, a bird's nest extract and the like, wherein the composite small-molecule active peptide is composed of small-molecule peptides such as nonapeptide-1, yeast polypeptide, hydrolyzed collagen, a leech extract, a lumbricus extract and an embryo extract. Through the combination and proportioning of various functional raw materials, the product can well solve the problem of dull skin, so that the skin using the essence can recover the normal vitality state, and the skin color is bright, red, moist and healthy.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a composite small-molecule active peptide whitening secondary polishing essence.
Background
The problem of excessive keratinization of the stratum corneum of the skin is constantly occurring due to the changing living environment, the widespread use of daily care products and the excessive use of cosmetic products applied, which cause the skin of the consumer to become more and more delicate and sensitive. The existing people are increased in working and living pressure, raised in dust around motor vehicle exhaust and other environmental pollution, and the atmospheric climate warming sunlight ultraviolet ray is enhanced, and in addition, the existing take-out food additives are used too much, so that the consumers have irregular food and drink on the dinner, the food and drink are greasy, the people have irregular work and rest in the night, and other reasons are integrated, the skin is influenced, and the body and the skin are in an extremely unbalanced state. Meanwhile, human fibrocytes gradually lose the regeneration capacity of the fibrocytes along with the increase of age and lack of nutrition, particularly ultraviolet rays, and the influence of various stresses of life and work is further deepened, so that the skin is yellowed, deposited with melanin, dark, lack of blood color, lack of normal luster and brightness and the like.
The lack of internal functions needs to be remedied from the outside, and the essence has the effects of activating and promoting cells to recover to normal and the like, so that the skin can be kept in a better state by using the essence.
The common nutrient molecules in water, emulsion and cream in the market have relatively large molecular weight, and have very limited absorption effect and permeability, so that the skin care effect is difficult to achieve. And most of essence is packaged by 30-300ml, so that once the essence is unsealed and used, the essence cannot be polluted, and the essence can only be placed at home at ordinary times and is inconvenient to carry on business trip and the like. The secondary polishing is one-time polishing, and the automatic aseptic integrated forming technology of blowing, filling and sealing (BFS) is adopted, so that the secondary polishing essence is prevented from being polluted in use, 1-1.5ml of secondary polishing essence is independently packaged, the size is small, the secondary polishing essence is convenient to carry, and compared with the traditional essence, the secondary polishing essence not only improves the portability and convenience of consumers in use, but also can ensure the safety in use.
Disclosure of Invention
The invention aims to provide an easily-absorbed composite small-molecule active peptide whitening secondary polishing essence, which mainly adopts the following technical scheme:
the invention relates to a micromolecular active peptide essence which comprises the following raw materials: the composition comprises small molecular compound active peptide, glycerol, carbomer, EDTA disodium, triethanolamine, 1, 3-propylene glycol, polyethylene glycol-200, modified Taohong Siwu decoction extract, rhodiola rosea extract, ginseng extract, mulberry root bark extract, hydrolyzed pearl, nicotinamide, glabridin, 3-o-ethyl ascorbic acid, arbutin, cubilose extract, plant essential oil and water.
Further, the weight ratio of the raw materials is as follows: 1-10 parts of composite small molecular active peptide, 2-10 parts of glycerol, 1-5 parts of carbomer, 1-5 parts of EDTA disodium, 1-5 parts of triethanolamine, 1-10 parts of 1, 3-propylene glycol, 1.1-1 part of polyethylene glycol, 0.6-6 parts of modified peach-red four-ingredient decoction extract, 0.1-1 part of rhodiola extract, 0.1-1 part of ginseng extract, 0.1-1 part of mulberry root bark extract, 0.1-1 part of hydrolyzed pearl, 1-5 parts of nicotinamide, 0.1-0.5 part of glabridin, 1-5 parts of 3-o-ethyl ascorbic acid, 1-5 parts of glycoside, 0.1-1 part of cubilose extract, 0.001-0.1 part of plant essential oil and 30-80 parts of water.
The improved peach-red four-ingredient decoction extract used in the invention is composed of a safflower extract, a peach kernel extract, a ligusticum wallichii extract, a angelica root extract, a rehmannia root extract and a peony root extract according to the weight ratio of 1:1:1:1:1:1, and according to the traditional classic formula of traditional Chinese medicine, namely peach-red four-ingredient decoction, the effective components contained in the improved peach-red four-ingredient decoction extract are water-soluble small molecular substances such as ferulic acid and the like.
The composite small molecule active peptide used in the invention is composed of any one of the following combinations:
composition 1: nonapeptide-1, yeast polypeptide, hydrolyzed collagen, leech extract, earthworm extract and embryo extract according to the weight ratio of 1:0.05:0.25:0.25:0.25:0.25, wherein the effective peptide chain structure is LTERA.
Composition 2: glutathione, tenglong oligopeptide, ground beetle oligopeptide, hydrolyzed collagen and oligopeptide-1 according to the weight ratio of 1:0.2:0.2:0.5:0.8, wherein the effective peptide chain structure is AVFIV.
Composition 3: hydrolyzed collagen, oligopeptide-6, woodlouse oligopeptide, carnosine and tetrapeptide-1 according to the weight ratio of 1:0.5:0.2:0.5:0.3, wherein the effective peptide chain structure is DLTAGF.
The effective peptide chain structures LTERA, AVFIV and DLTAGF are expressed as the arrangement sequence of amino acids, letters are English abbreviations of the amino acids, and each letter represents as follows: alanine, Ala, A, valine, Val, V, leucine, Leu, L, isoleucine, Ile, I, methionine, Met, M, proline, Pro, P, phenylalanine, Phe, F, tryptophan, Trp, W, serine, Ser, S, threonine, Thr, T, tyrosine, Tyr, Y, cysteine, Cys, C, asparagine, Asn, N, glutamine, Gln, Q, glycine, Gly, G, aspartic acid, Asp, D, glutamic acid, Glu, E, lysine, Lys, K, arginine, Arg, R, histidine, His, H.
The molecular weight of the composite small molecule active peptide used in the invention is less than 1500D, and the composite small molecule active peptide provides a multi-component and multi-nutrient transdermal substance basis and thrombolysis and plaque dissolving active ingredients through combination and proportioning. The 6 extracts are used in a compatibility and combination mode, and are improved according to the prescription of a traditional famous formula of the traditional Chinese medicine, namely peach red four-ingredient decoction, the peach red four-ingredient decoction has long clinical use, has clear effects of nourishing blood, invigorating blood circulation and dispelling blood stasis, and contains water-soluble small molecular substances such as ferulic acid and the like, so that the peach red four-ingredient decoction has a good anti-oxidation effect; the composition is innovative when applied to skin care essence.
The peach kernel, recorded in the 2020 edition of Chinese pharmacopoeia, is bitter, sweet and neutral in nature. It enters heart, liver and large intestine meridians. Has the functions of promoting blood circulation to disperse blood clots, relaxing bowels, relieving cough and asthma. Can be used for treating amenorrhea, dysmenorrhea, abdominal mass, pulmonary abscess, intestinal abscess, traumatic injury, constipation due to intestinal dryness, cough, and asthma. Walnut kernel is sweet in nature and warm. It enters kidney, lung and large intestine meridians. Has the functions of tonifying kidney, warming lung and moistening intestine. Can be used for treating kidney yang deficiency, soreness of waist and knees, sexual impotence, spermatorrhea, asthenic cold, cough, intestinal dryness, and constipation. According to the invention, the original formula of the peach-red Siwu decoction is improved, walnut kernels replace peach kernels, and the common functions of the walnut kernels, namely sweet nature, large intestine meridian entering and intestine moistening are taken. As is known, dark and yellow skin color is related to toxin and garbage in vivo, the intestine and stomach peristalsis is promoted to discharge toxin in vivo through the components for relaxing bowel, and the problems of dark and dull skin color, no light, spots and the like can be easily solved after the toxin is cleaned. This is also one of the inventive features of the present invention.
The plant essential oil in the invention is any one or more of rose oil, lavender oil, clove oil, Roman chamomile oil and geranium oil.
The preparation method of the essence comprises the following steps:
(1) and adding carbomer into water, and swelling for 24-48 hours at room temperature.
(2) Adding disodium EDTA, Carthami flos extract, semen Persicae extract, rhizoma Ligustici Chuanxiong extract, radix Angelicae sinensis extract, radix rehmanniae extract, radix Paeoniae extract, radix Rhodiolae extract, Ginseng radix extract, cortex Mori extract, hydrolyzed Margarita, nicotinamide, glabridin, 3-o-ethyl ascorbic acid, arbutin, and nidus Collocaliae extract into water, heating to 50 + -5 deg.C for dissolving, stirring, and cooling to room temperature.
(3) Mixing plant essential oil, glycerol, 1, 3-propylene glycol, and polyethylene glycol-200, and stirring.
(4) Sequentially adding (2) and (3) into (1), adding triethanolamine, stirring, optionally adding antiseptic, filtering with microporous membrane, and sterilizing.
The preservative in the invention is methyl hydroxybenzoate and phenoxyethanol.
The application method of the essence comprises the following steps: the lotion is used in the morning and evening, after toner, before essence milk and cream. The product has good ductility, and can be applied on face uniformly by only 3 drops.
The essence disclosed by the invention contains various micromolecular active peptide components, can keep moisture for a long time, improve the luster, and enable the skin to recover tender and compact vitality and luster.
The essence can easily pass through the horny layer, enter the epidermis, penetrate into the substrate and be absorbed by the basal cells, and protect the skin from the roots. The essence can well solve the problem of dull skin through the combination and proportioning of various functional raw materials, so that the skin regularly using the essence can recover a healthy, ruddy and bright state.
In order to further examine the quality of the essence of the invention, 8 different samples are respectively prepared, and employees of a company and 30 relatives (female 26 and male 4) are recruited to carry out voluntary and free trial, and the experiment is as follows:
(1) experimental sample
Sample 1: the essence of example 1.
Sample 2: the essence of example 2.
Sample 3: the essence of example 3.
Sample 4: 10 weight parts of composite micromolecular active peptide (nonapeptide-1, yeast polypeptide according to the weight ratio of 1: 1), 3 weight parts of glycerol, 2 weight parts of carbomer, 2 weight parts of EDTA disodium, 1 weight part of triethanolamine, 1 weight part of 1, 3-propylene glycol, 2000.2 weight parts of polyethylene glycol, 0.5 weight part of safflower extract, 0.5 weight part of peach kernel extract, 0.5 weight part of ligusticum wallichii extract, 0.5 weight part of angelica root extract, 0.5 weight part of rehmannia root extract, 0.5 weight part of peony root extract, 0.5 weight part of red sage root extract, 0.5 weight part of ginseng extract, 0.5 weight part of mulberry root bark extract, 1 weight part of hydrolyzed pearl, 2 weight parts of nicotinamide, 0.2 weight part of glabridin, 2 weight parts of 3-o-ethyl ascorbic acid, 2 weight parts of arbutin, 0.5 weight part of bird's nest extract, 0.1 weight part of clove oil, 0.5 weight part of carbomer, 0.5 weight part of EDTA disodium, 0.5 weight part of triethanolamine, 0.5 weight part of rehmannia root extract, 0.5 weight part of rhizoma corydalis extract, 0.5 weight part of radix et rhizoma corydalis extract, 0.5 weight of radix sedi extract, 1, and the like, 68.5 parts of water. (10 g per part by weight)
Sample 5: 5 parts of composite small-molecule active peptide (nonapeptide-1, yeast polypeptide, hydrolyzed collagen, a leech extract, a lumbricus extract and an embryo extract according to the weight ratio of 1:0.05:0.25:0.25: 0.25) by weight, 3 parts of glycerol, 2 parts of carbomer, 2 parts of EDTA disodium, 1 part of triethanolamine, 1 part of 1, 3-propylene glycol, 2000.2 parts of polyethylene glycol, 0.5 part of a rhodiola rosea extract, 0.5 part of a ginseng extract, 0.5 part of a mulberry root bark extract, 1 part of hydrolyzed pearl, 2 parts of nicotinamide, 0.2 part of glabridin, 2 parts of 3-o-ethyl ascorbic acid, 2 parts of arbutin, 0.5 part of a bird's nest extract, 0.1 part of geranium oil and 76.5 parts of water. (50 g per part by weight)
Sample 6: 10 parts of composite micromolecule active peptide (composed of glutathione, tianlong oligopeptide, woodlouse oligopeptide, hydrolyzed collagen and oligopeptide-1 according to the weight ratio of 1:0.2:0.2:0.5: 0.8), 3 parts of glycerol, 2 parts of carbomer, 2 parts of EDTA disodium, 1 part of triethanolamine, 1 part of 1, 3-propylene glycol, 2000.2 parts of polyethylene glycol, 0.5 part of rhodiola rosea extract, 0.5 part of ginseng extract, 0.5 part of mulberry root bark extract, 1 part of hydrolyzed pearl, 2 parts of nicotinamide, 0.2 part of glabridin, 2 parts of 3-o-ethyl ascorbic acid, 2 parts of arbutin, 0.5 part of nidus Collocalia extract, 0.1 part of Roman chamomile oil and 71.5 parts of water. (10 g per part by weight)
Sample 7: 10 parts of composite micromolecule active peptide (consisting of hydrolyzed collagen, oligopeptide-6, woodlouse oligopeptide, carnosine and tetrapeptide-1 according to the weight ratio of 1:0.5:0.2:0.5: 0.3), 3 parts of glycerol, 2 parts of carbomer, 2 parts of EDTA disodium, 1 part of triethanolamine, 1 part of 1, 3-propylene glycol, 2000.2 parts of polyethylene glycol, 0.5 part of rhodiola rosea extract, 0.5 part of ginseng extract, 0.5 part of mulberry root bark extract, 1 part of hydrolyzed pearl, 2 parts of nicotinamide, 0.2 part of glabridin, 2 parts of 3-o-ethyl ascorbic acid, 2 parts of arbutin, 0.5 part of nidus Collocaliae extract, 0.1 part of clove oil and 71.5 parts of water. (50 g per part by weight)
Sample 8: 5 parts of glutathione, 3 parts of glycerol, 2 parts of carbomer, 2 parts of EDTA disodium, 1 part of triethanolamine, 1 part of 1, 3-propylene glycol, 2000.2 parts of polyethylene glycol, 0.5 part of rhodiola rosea extract, 0.5 part of ginseng extract, 0.5 part of mulberry root bark extract, 1 part of hydrolyzed pearl, 2 parts of nicotinamide, 0.2 part of glabridin, 2 parts of 3-o-ethyl ascorbic acid, 2 parts of arbutin, 0.5 part of bird's nest extract, 0.1 part of geranium oil and 76.5 parts of water. (10 g per part by weight)
(2) Experimental methods
8 samples are respectively tried for 60 days for observation, and the evaluation scores of the samples are obtained from five aspects of skin darkness improvement (3 points), moisture keeping (2 points), elasticity improvement (3 points), fragrance (1 point) and ductility (1 point), and the results are as follows:
as a result, the evaluation scores of the products of the present invention (sample 1, sample 2, and sample 3) were high. Especially, the effect difference caused by the raw material composition and different proportions of different composite small molecule active peptides is obvious, and the raw material composition and proportion of the formula of the invention have obvious effect.
Detailed Description
The present invention will be described in further detail with reference to examples, but the present invention is not limited thereto.
Example 1
A composite micromolecule active peptide essence comprises the following raw and auxiliary materials: 10 parts of composite small molecule active peptide (nonapeptide-1, yeast polypeptide, hydrolyzed collagen, leech extract, earthworm extract and embryo extract according to the weight ratio of 1:0.05:0.25:0.25:0.25: 0.25) by weight, 3 parts of glycerol, 2 parts of carbomer, 2 parts of EDTA disodium, 1 part of triethanolamine, 1, 3-propylene glycol, 2000.2 parts of polyethylene glycol, 0.5 part of safflower extract, 0.5 part of walnut kernel extract, 0.5 part of ligusticum wallichii extract, 0.5 part of angelica root extract, 0.5 part of rehmannia root extract, 0.5 part of peony root extract, 0.5 part of rhodiola root extract, 0.5 part of ginseng extract, 0.5 part of mulberry root bark extract, 1 part of hydrolyzed pearl, 2 parts of nicotinamide, 0.2 part of glabridin and 2-o-ethyl ascorbic acid by weight, 2 parts of arbutin, 0.5 part of cubilose extract, 0.1 part of rose oil and 68.5 parts of water. (100 g per part by weight)
Example 2
A composite micromolecule active peptide essence comprises the following raw and auxiliary materials: 1 part of composite micromolecule active peptide (composed of glutathione, tianlong oligopeptide, woodlouse oligopeptide, hydrolyzed collagen and oligopeptide-1 according to the weight ratio of 1:0.2:0.2:0.5: 0.8), 3 parts of glycerol, 2 parts of carbomer, 2 parts of EDTA disodium, 1 part of triethanolamine, 1 part of 1, 3-propylene glycol, 1 part of polyethylene glycol-2000.2 parts of polyethylene glycol, 0.5 part of safflower extract, 0.5 part of peach kernel extract, 0.5 part of ligusticum wallichii extract, 0.5 part of angelica root extract, 0.5 part of rehmannia root extract, 0.5 part of peony root extract, 0.5 part of rhodiola rosea extract, 0.5 part of ginseng extract, 0.5 part of mulberry root bark extract, 1 part of hydrolyzed pearl, 2 parts of nicotinamide, 0.2 part of glabridin, 2 parts of 3-o-ethyl ascorbic acid, 2 parts of arbutin, 0.5 part of cubilose extract, 0.1 part of lavender oil and 77.5 parts of water. (100 g per part by weight)
Example 3
A composite micromolecule active peptide essence comprises the following raw and auxiliary materials: 5 parts of composite micromolecular active peptide (consisting of hydrolyzed collagen, oligopeptide-6, woodlouse oligopeptide, carnosine and tetrapeptide-1 according to the weight ratio of 1:0.5:0.2:0.5: 0.3), 3 parts of glycerol, 2 parts of carbomer, 2 parts of EDTA disodium, 1 part of triethanolamine, 1 part of 1, 3-propylene glycol, 2000.2 parts of polyethylene glycol, 0.5 part of safflower extract, 0.5 part of peach kernel extract, 0.5 part of ligusticum wallichii extract, 0.5 part of angelica root extract, 0.5 part of rehmannia root extract, 0.5 part of peony root extract, 0.5 part of rhodiola rosea extract, 0.5 part of ginseng extract, 0.5 part of mulberry root bark extract, 1 part of hydrolyzed pearl, 2 parts of nicotinamide, 0.2 part of glabridin, 2 parts of 3-o-ethyl ascorbic acid, 2 parts of arbutin, 0.5 part of cubilose extract, 0.1 part of Roman chamomile oil and 73.5 parts of water. The preparation method (10 g per weight portion) comprises the following steps:
(1) and adding carbomer into water, and swelling for 24-48 hours at room temperature.
(2) Adding disodium EDTA, Carthami flos extract, semen Persicae extract, rhizoma Ligustici Chuanxiong extract, radix Angelicae sinensis extract, radix rehmanniae extract, radix Paeoniae extract, radix Rhodiolae extract, Ginseng radix extract, cortex Mori extract, hydrolyzed Margarita, nicotinamide, glabridin, 3-o-ethyl ascorbic acid, arbutin, and nidus Collocaliae extract into water, heating to 50 + -5 deg.C for dissolving, stirring, and cooling to room temperature.
(3) Mixing plant essential oil, glycerol, 1, 3-propylene glycol, and polyethylene glycol-200, and stirring.
(4) Sequentially adding the (2) and the (3) into the (1), adding triethanolamine, stirring uniformly, filtering with a microporous filter membrane, and sterilizing to obtain the product.
Claims (8)
1. The composite small-molecule active peptide whitening secondary polishing essence is characterized by comprising the following raw materials: the composition comprises small molecular compound active peptide, glycerol, carbomer, EDTA disodium, triethanolamine, 1, 3-propylene glycol, polyethylene glycol-200, modified Taohong Siwu decoction extract, rhodiola rosea extract, ginseng extract, mulberry root bark extract, hydrolyzed pearl, nicotinamide, glabridin, 3-o-ethyl ascorbic acid, arbutin, cubilose extract, plant essential oil and water.
2. The compound small-molecule active peptide whitening secondary polishing essence liquid as claimed in claim 1, characterized in that the essence liquid comprises the following raw materials: 1-10 parts of composite small molecular active peptide, 2-10 parts of glycerol, 1-5 parts of carbomer, 1-5 parts of EDTA disodium, 1-5 parts of triethanolamine, 1-10 parts of 1, 3-propylene glycol, 1.1-1 part of polyethylene glycol, 0.6-6 parts of modified peach-red four-ingredient decoction extract, 0.1-1 part of rhodiola extract, 0.1-1 part of ginseng extract, 0.1-1 part of mulberry root bark extract, 0.1-1 part of hydrolyzed pearl, 1-5 parts of nicotinamide, 0.1-0.5 part of glabridin, 1-5 parts of 3-o-ethyl ascorbic acid, 1-5 parts of glycoside, 0.1-1 part of cubilose extract, 0.001-0.1 part of plant essential oil and 30-80 parts of water.
3. The composite small-molecule active peptide whitening secondary polishing essence liquid as claimed in claim 1 or 2, wherein the modified peach-red four-ingredient decoction extract is composed of safflower extract, peach kernel extract, ligusticum wallichii extract, angelica root extract, rehmannia root extract and peony root extract according to a weight ratio of 1:1:1: 1.
4. The whitening sub-polishing essence containing small-molecule active peptides as claimed in claim 1 or 2, wherein the small-molecule active peptides are composed of nonapeptide-1, yeast polypeptide, hydrolyzed collagen, leech extract, lumbricus extract and embryo extract according to the weight ratio of 1:0.05:0.25:0.25:0.25:0.25, wherein the effective peptide chain structure is LTERA.
5. The compound small molecule active peptide whitening secondary polishing essence liquid as claimed in claim 1 or 2, characterized in that the compound small molecule active peptide is composed of glutathione, tianlong oligopeptide, ground beetle oligopeptide, hydrolyzed collagen and oligopeptide-1 according to the weight ratio of 1:0.2:0.2:0.5:0.8, wherein the effective peptide chain structure contained in the essence liquid is AVFIV.
6. The whitening sub-polishing essence containing small-molecule bioactive peptides as claimed in claim 1 or 2, wherein the small-molecule bioactive peptides are composed of hydrolyzed collagen, oligopeptide-6, Eupolyphaga oligopeptide, carnosine and tetrapeptide-1 according to the weight ratio of 1:0.5:0.2:0.5:0.3, wherein the effective peptide chain structure contained in the essence is DLTAGF.
7. The compound small-molecule active peptide whitening secondary polishing essence liquid as claimed in claim 1 or 2, wherein the plant essential oil is one or more of rose oil, lavender oil, clove oil, roman chamomile oil and geranium oil.
8. The compound small-molecule active peptide whitening secondary polishing essence liquid as claimed in claim 1 or 2, wherein the essence liquid is applied to the preparation of cosmetics for improving dull skin.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110063911A (en) * | 2019-06-11 | 2019-07-30 | 包磊 | A kind of compound small active peptides Essence |
| CN112494406A (en) * | 2020-12-25 | 2021-03-16 | 云南科妍医药生物科技有限公司 | Whitening and freckle-removing cosmetic and preparation method thereof |
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2021
- 2021-09-28 CN CN202111143053.5A patent/CN115054564A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110063911A (en) * | 2019-06-11 | 2019-07-30 | 包磊 | A kind of compound small active peptides Essence |
| CN112494406A (en) * | 2020-12-25 | 2021-03-16 | 云南科妍医药生物科技有限公司 | Whitening and freckle-removing cosmetic and preparation method thereof |
Non-Patent Citations (1)
| Title |
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| 丁兆平: "《发现本草之旅 2》", 中国医药科技出版社, pages: 358 * |
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Application publication date: 20220916 |