CN110063911A - A kind of compound small active peptides Essence - Google Patents
A kind of compound small active peptides Essence Download PDFInfo
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- CN110063911A CN110063911A CN201910500214.8A CN201910500214A CN110063911A CN 110063911 A CN110063911 A CN 110063911A CN 201910500214 A CN201910500214 A CN 201910500214A CN 110063911 A CN110063911 A CN 110063911A
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- sodium hyaluronate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Birds (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to a kind of compound small active peptides Essences, contain compound small active peptides, butanediol, 1, the raw materials such as 2- pentanediol, glycerin polyether -26, wherein compound small active peptides are made of small-molecular peptides such as glutathione, oligopeptides -1, hydrolysis placenta (sheep) extract, ground bettle oligopeptides, hydrolysis of keratin, oligopeptides -6.By the combination matching of multiple efficacies raw material, can be very good to solve skin sensitive issue, so that being able to maintain good state using the skin of this Essence.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of compound small active peptides Essence.
Background technique
Due to the variation of living environment, daily nursing product be widely used and the excessive use of mask sheet class product, lead
The problem of causing the skin of consumer to become more and more fragile sensitive, causing keratoderma excessive keratinization emergence.Now
People due to various pressure, there are also irregular, kinds of eating under various pollutions of surrounding, present food less health including upper meal
Kind reason is comprehensive, has influenced skin, skin is allowed to be in a kind of unbalanced state of extreme.Meanwhile the fibrocyte of people can be with
The growth at age and the body and mind of people influence, at leisure without the power of regeneration of cell, especially ultraviolet light, life, work
The influence for the various pressure made even more deepens such case, it is caused in this way the result is that skin water holding decreased capacity.Women
Skin inherently contain moisture-keeping functions, but with the age, the influence of the environment such as pressure, slowly also just become without it is original that
It is good.
The shortage of built-in function, we will remedy from outside, and Essence contains moisturizing, promotion cytothesis etc. and makees
With, so, Essence is made good use of, skin can be allowed to keep better state.
The common water in market, lotion, the nutrient molecule in face cream are because component volume is relatively large, assimilation effect and infiltration
Ability is extremely limited, it is difficult to reach preferable skin effect.
Summary of the invention
The object of the present invention is to provide a kind of compound small active peptides Essence for being easy to absorb, the present invention is mainly used
Following technical scheme:
A kind of small active peptides Essence of the invention includes following raw material: compound small active peptides, butanediol, 1,
2- pentanediol, glycerin polyether -26, double-PEG-15 methyl ether dimethicones, lecithin, Sodium Hyaluronate, hydrolysis are transparent
Matter acid sodium, Sodium Hyaluronate cross-linked polymer, acetylation Sodium Hyaluronate, plants essential oil, water.
Further, the weight proportion of raw material are as follows: compound 1~10 parts by weight of small active peptides, 5~10 weight of butanediol
Part, 5~10 parts by weight of 1,2- pentanediol, 1~10 parts by weight of glycerin polyether -26, double-PEG-15 methyl ether polydimethylsiloxanes
1~10 parts by weight of alkane, 1~10 parts by weight of lecithin, 0.1~0.5 parts by weight of Sodium Hyaluronate, hydrolysis Sodium Hyaluronate 0.1~
0.5 parts by weight, 0.1~0.5 parts by weight of Sodium Hyaluronate cross-linked polymer, 0.1~0.5 parts by weight of acetylation Sodium Hyaluronate,
0.1~1 parts by weight of plants essential oil, 10~50 parts by weight of water.
Compound small active peptides used in the present invention are made of any one of following combination:
Composition 1: glutathione, oligopeptides -1, hydrolysis placenta (sheep) extract, hydrolytic collagen, ascorbyl polypeptide are according to 1:
The weight ratio of 0.5:0.2:2:1 forms, wherein being HGETEAP containing effective peptide chain structure.
Composition 2: glutathione, sky dragon oligopeptides, ground bettle oligopeptides, hydrolysis of keratin, oligopeptides -6 are according to 1:0.2:0.3:
The weight ratio of 0.5:0.6 forms, wherein being ENTTPHE containing effective peptide chain structure.
Composition 3: hydrolytic collagen, oligopeptides -6, ground bettle oligopeptides, carnosine are formed according to the weight ratio of 1:0.5:0.3:0.2,
In containing effective peptide chain structure be CCEAGFP.
Wherein effective peptide chain structure HGETEAPYM, ENTTPHEAV, CCEAGFPHVAP, the structure representation are amino acid
Put in order, letter be amino acid english abbreviation, it is each letter represent it is as follows: alanine, Ala, A, valine, Val, V are bright
Propylhomoserin, Leu, L, isoleucine, Ile, I, methionine, Met, M, proline, Pro, P, phenylalanine, Phe, F, tryptophan,
Trp, W, serine, Ser, S, threonine, Thr, T, tyrosine, Tyr, Y, cysteine, Cys, C, asparagine, Asn, N, paddy
Glutamine, Gln, Q, glycine, Gly, G, aspartic acid, Asp, D, glutamic acid, Glu, E, lysine, Lys, K, arginine,
Arg, R, histidine, His, H.
Compound small active peptides, molecular weight used in the present invention are respectively less than 2000D, by combination matching, provide
Multicomponent, polyauxotrophic material base.
Plants essential oil in the present invention is rose oil, in lavender oil, caryophyllus oil, Rome oil of chamomile, pelargonium oil
Any one or more composition.
Essence of the present invention the preparation method comprises the following steps:
(1) by Sodium Hyaluronate, hydrolysis Sodium Hyaluronate, Sodium Hyaluronate cross-linked polymer, acetylation Sodium Hyaluronate
It is added to the water, room temperature swollen 24~48 hours.
(2) butanediol, 1,2- pentanediol are added in above-mentioned sodium hyaluronate solution, stir evenly, adds compound small
Molecular activity peptide, glycerin polyether -26, double-PEG-15 methyl ether dimethicones, lecithin, be heated to 80 ± 5 DEG C it is molten
Solution, stirs evenly, medical fluid to be mixed is cooled to room temperature.
(3) plants essential oil is added in above-mentioned admixing medical solutions, is stirred evenly, added or not adding preservative agent, high pressure steam sterilization,
To obtain the final product.
Preservative is methyl hydroxybenzoate, ethyl hydroxy benzoate in the present invention.
The application method of Essence of the present invention are as follows: sooner or later daily, after toner, used before essence cream and face cream.This
Product have good ductility, only need 3 drops, so that it may uniformly smear face.
Containing there are many small active peptides ingredient in Essence of the present invention, can lasting moisturizing, promote elasticity, desalination is thin
Line enables skin restore tender compact vigor honorable.
Essence of the present invention can easily pass through cuticula, into epidermis, then penetrate into substrate and absorbed by basal cell, from
Root skin care.The Essence passes through the combination matching of multiple efficacies raw material, can be very good to solve skin sensitive issue, so that
Good state is able to maintain using the skin of this Essence.
For the quality for further investigating Essence of the present invention, 8 parts of different samples are prepared respectively, 10 people is looked for try out, it is real
It tests as follows:
(1) laboratory sample
Sample 1: the Essence of embodiment 1.
Sample 2: the Essence of embodiment 2.
Sample 3: the Essence of embodiment 3.
Sample 4: (glutathione, hydrolysis placenta (sheep) extract, hydrolytic collagen, resists oligopeptides -1 compound small active peptides
Bad hematic acid polypeptide is formed according to the weight ratio of 1:1:1:1:1) 10 parts by weight, 10 parts by weight of butanediol, 5 weight of 1,2- pentanediol
Part, 10 parts by weight of glycerin polyether -26, double 10 parts by weight of-PEG-15 methyl ether dimethicone, 1 parts by weight of lecithin,
0.5 parts by weight of Sodium Hyaluronate, hydrolysis 0.1 parts by weight of Sodium Hyaluronate, 0.1 parts by weight of Sodium Hyaluronate cross-linked polymer, second
Acylated 0.5 parts by weight of Sodium Hyaluronate, 1 parts by weight of rose oil, 50 parts by weight of water.(every parts by weight 10g)
Sample 5: compound small active peptides (glutathione, sky dragon oligopeptides, ground bettle oligopeptides, hydrolysis of keratin, oligopeptides -6
Formed according to the weight ratio of 1:1:1:1:1) 5 parts by weight, 5 parts by weight of butanediol, 10 parts by weight of 1,2- pentanediol, glycerin polyether-
26 1 parts by weight, double 1 parts by weight of-PEG-15 methyl ether dimethicone, 1 parts by weight of lecithin, 0.1 weight of Sodium Hyaluronate
Measure part, hydrolysis 0.5 parts by weight of Sodium Hyaluronate, 0.5 parts by weight of Sodium Hyaluronate cross-linked polymer, acetylation Sodium Hyaluronate
0.1 parts by weight, 0.1 parts by weight of lavender oil, 10 parts by weight of water.(every parts by weight 50g)
Sample 6: (glutathione, hydrolysis placenta (sheep) extract, hydrolytic collagen, resists oligopeptides -1 compound small active peptides
Bad hematic acid polypeptide is formed according to the weight ratio of 1:5:1:5:1) 10 parts by weight, 10 parts by weight of butanediol, 5 weight of 1,2- pentanediol
Part, 10 parts by weight of glycerin polyether -26, double 10 parts by weight of-PEG-15 methyl ether dimethicone, 1 parts by weight of lecithin,
0.5 parts by weight of Sodium Hyaluronate, hydrolysis 0.1 parts by weight of Sodium Hyaluronate, 0.1 parts by weight of Sodium Hyaluronate cross-linked polymer, second
Acylated 0.5 parts by weight of Sodium Hyaluronate, 1 parts by weight of Rome oil of chamomile, 50 parts by weight of water.(every parts by weight 10g)
Sample 7: compound small active peptides (glutathione, sky dragon oligopeptides, ground bettle oligopeptides, hydrolysis of keratin, oligopeptides -6
Formed according to the weight ratio of 5:1:5:1:5) 5 parts by weight, 5 parts by weight of butanediol, 10 parts by weight of 1,2- pentanediol, glycerin polyether-
26 1 parts by weight, double 1 parts by weight of-PEG-15 methyl ether dimethicone, 1 parts by weight of lecithin, 0.1 weight of Sodium Hyaluronate
Measure part, hydrolysis 0.5 parts by weight of Sodium Hyaluronate, 0.5 parts by weight of Sodium Hyaluronate cross-linked polymer, acetylation Sodium Hyaluronate
0.1 parts by weight, 0.1 parts by weight of caryophyllus oil, 10 parts by weight of water.(every parts by weight 50g)
Sample 8: 5 parts by weight of glutathione, 10 parts by weight of butanediol, 5 parts by weight of 1,2- pentanediol, glycerin polyether -2610
Parts by weight, double 10 parts by weight of-PEG-15 methyl ether dimethicone, 1 parts by weight of lecithin, 0.5 weight of Sodium Hyaluronate
Part, hydrolysis 0.1 parts by weight of Sodium Hyaluronate, 0.1 parts by weight of Sodium Hyaluronate cross-linked polymer, acetylation Sodium Hyaluronate 0.5
Parts by weight, 1 parts by weight of pelargonium oil, 50 parts by weight of water.(every parts by weight 10g)
(2) experimental method
Observation on probation is carried out to 8 parts of samples respectively, from lasting moisturizing (3 points), promotes elastic (2 points), desalination microgroove (3
Point), fragrant odour (1 point), the aspect experience of ductility (1 point) five, acquire each sample evaluation score, it is as a result as follows:
Sample number into spectrum | Evaluate score |
Sample 1 | 94 |
Sample 2 | 96 |
Sample 3 | 91 |
Sample 4 | 82 |
Sample 5 | 86 |
Sample 6 | 80 |
Sample 7 | 81 |
Sample 8 | 78 |
As a result as it can be seen that the evaluation score of product of the present invention (sample 1, sample 2, sample 3) is higher.In particular, in that different composite
The raw material of small active peptides forms, difference on effect caused by different ratio is obvious, and the raw material of inventive formulation forms and matches
Than with significant effect.
Specific embodiment
More detailed description is carried out to the present invention below with reference to embodiment, but is not limitation of the invention.
Embodiment 1
A kind of compound small active peptides Essence, supplementary material composition are as follows: compound small active peptides (glutathione, widow
Peptide -1, hydrolysis placenta (sheep) extract, hydrolytic collagen, ascorbyl polypeptide are formed according to the weight ratio of 1:0.5:0.2:2:1) 10
Parts by weight, 10 parts by weight of butanediol, 5 parts by weight of 1,2- pentanediol, 10 parts by weight of glycerin polyether -26, double-PEG-15 methyl ethers
10 parts by weight of dimethyl silicone polymer, 1 parts by weight of lecithin, 0.5 parts by weight of Sodium Hyaluronate, hydrolysis 0.1 weight of Sodium Hyaluronate
Measure part, 0.1 parts by weight of Sodium Hyaluronate cross-linked polymer, 0.5 parts by weight of acetylation Sodium Hyaluronate, 1 parts by weight of rose oil,
50 parts by weight of water.(every parts by weight 100g)
Embodiment 2
A kind of compound small active peptides Essence, supplementary material composition are as follows: compound small active peptides (glutathione, day
Imperial oligopeptides, ground bettle oligopeptides, hydrolysis of keratin, oligopeptides -6 are formed according to the weight ratio of 1:0.2:0.3:0.5:0.6) 1 parts by weight,
5 parts by weight of butanediol, 10 parts by weight of 1,2- pentanediol, 1 parts by weight of glycerin polyether -26, double-PEG-15 methyl ether poly dimethyls
1 parts by weight of siloxanes, 0.1 parts by weight of Sodium Hyaluronate, hydrolyze 0.5 parts by weight of Sodium Hyaluronate, are transparent 1 parts by weight of lecithin
0.5 parts by weight of matter acid sodium cross-linked polymer, 0.1 parts by weight of acetylation Sodium Hyaluronate, 0.1 parts by weight of lavender oil, 10 weight of water
Measure part.(every parts by weight 500g)
Embodiment 3
A kind of compound small active peptides Essence, supplementary material composition are as follows: compound small active peptides (hydrolytic collagen, widow
Peptide -6, ground bettle oligopeptides, carnosine are formed according to the weight ratio of 1:0.5:0.3:0.2) 5 parts by weight, 8 parts by weight of butanediol, 1,2-
10 parts by weight of pentanediol, -263 parts by weight of glycerin polyether, double 5 parts by weight of-PEG-15 methyl ether dimethicone, lecithin
2 parts by weight, 0.3 parts by weight of Sodium Hyaluronate, hydrolysis 0.3 parts by weight of Sodium Hyaluronate, 0.2 weight of Sodium Hyaluronate cross-linked polymer
Measure part, 0.1 parts by weight of acetylation Sodium Hyaluronate, 0.2 parts by weight of Rome oil of chamomile, 50 parts by weight of water.(every parts by weight 10g)
The preparation method comprises the following steps:
(1) by Sodium Hyaluronate, hydrolysis Sodium Hyaluronate, Sodium Hyaluronate cross-linked polymer, acetylation Sodium Hyaluronate
It is added to the water, room temperature swollen 48 hours.
(2) butanediol, 1,2- pentanediol are added in above-mentioned sodium hyaluronate solution, stir evenly, adds compound small
Molecular activity peptide, glycerin polyether -26, double-PEG-15 methyl ether dimethicones, lecithin are heated to 80 DEG C of dissolutions, stir
It mixes uniformly, medical fluid to be mixed is cooled to room temperature.
(3) plants essential oil is added in above-mentioned admixing medical solutions, is stirred evenly, high pressure steam sterilization to get.
Embodiment 4
Small active peptides Essence prepared by Example 2, giving 10 people of intra-company employee, (8 people of women, male 2
People) it is on probation, after 60 days, there are 8 people to feel to be able to ascend elasticity, desalination microgroove, there are 10 people to feel being capable of lasting moisturizing.
Claims (7)
1. a kind of compound small active peptides Essence, it is characterised in that the Essence includes following raw material: compound small molecule
Active peptide, butanediol, 1,2- pentanediol, glycerin polyether -26, double-PEG-15 methyl ether dimethicones, lecithin, thoroughly
Bright matter acid sodium, hydrolysis Sodium Hyaluronate, Sodium Hyaluronate cross-linked polymer, acetylation Sodium Hyaluronate, plants essential oil, water.
2. compound small active peptides Essence as described in claim 1, it is characterised in that the Essence includes following original
Material: compound 1~10 parts by weight of small active peptides, 5~10 parts by weight of butanediol, 5~10 parts by weight of 1,2- pentanediol, glycerol are poly-
1~10 parts by weight of ether -26, double 1~10 parts by weight of-PEG-15 methyl ether dimethicone, 1~10 parts by weight of lecithin,
0.1~0.5 parts by weight of Sodium Hyaluronate, hydrolysis 0.1~0.5 parts by weight of Sodium Hyaluronate, Sodium Hyaluronate cross-linked polymer 0.1
~0.5 parts by weight, 0.1~0.5 parts by weight of acetylation Sodium Hyaluronate, 0.1~1 parts by weight of plants essential oil, 10~50 weight of water
Part.
3. compound small active peptides Essence as claimed in claim 1 or 2, it is characterised in that the compound small molecule is living
Property peptide be by glutathione, oligopeptides -1, hydrolysis placenta (sheep) extract, hydrolytic collagen, ascorbyl polypeptide is according to 1:0.5:
The weight ratio of 0.2:2:1 forms, wherein being HGETEAP containing effective peptide chain structure.
4. compound small active peptides Essence as claimed in claim 1 or 2, it is characterised in that the compound small molecule is living
Property peptide is by glutathione, sky dragon oligopeptides, ground bettle oligopeptides, hydrolysis of keratin, oligopeptides -6 according to 1:0.2:0.3:0.5:0.6
Weight ratio composition, wherein being ENTTPHE containing effective peptide chain structure.
5. compound small active peptides Essence as claimed in claim 1 or 2, it is characterised in that the compound small molecule is living
Property peptide is made of hydrolytic collagen, oligopeptides -6, ground bettle oligopeptides, carnosine according to the weight ratio of 1:0.5:0.3:0.2, wherein containing
Effective peptide chain structure is CCEAGFP.
6. compound small active peptides Essence as claimed in claim 1 or 2, it is characterised in that the plants essential oil is rose
Rare caul-fat, lavender oil, caryophyllus oil, Rome oil of chamomile, any one or more composition in pelargonium oil.
7. compound small active peptides Essence as claimed in claim 1 or 2, it is characterised in that the Essence passes through a variety of function
The combination matching for imitating raw material can be very good to solve skin sensitive issue, so that being able to maintain using the skin of this Essence good
Good state.
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111588657A (en) * | 2020-06-09 | 2020-08-28 | 广州市轩颜化妆品有限公司 | Vitreous chromogen and blue copper peptide double-effect combined essence and preparation method thereof |
CN114948837A (en) * | 2022-04-21 | 2022-08-30 | 山东仟草医药科技有限公司 | Composite micromolecule active peptide wrinkle-removing secondary polishing essence |
CN114948785A (en) * | 2022-04-21 | 2022-08-30 | 山东仟草医药科技有限公司 | Compound small-molecule active peptide essence capable of astringing and relieving acne red and swollen and secondarily polishing |
CN115054564A (en) * | 2021-09-28 | 2022-09-16 | 山东仟草医药科技有限公司 | Composite small-molecule active peptide whitening secondary polishing essence |
CN115054532A (en) * | 2021-09-28 | 2022-09-16 | 山东仟草医药科技有限公司 | Compound small-molecule active peptide moisturizing secondary polishing essence |
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CN101293929A (en) * | 2007-04-29 | 2008-10-29 | 王鹤尧 | Preparation and application of natural polypeptide medicaments derivative |
CN106137906A (en) * | 2015-04-27 | 2016-11-23 | 广州慕咖伦生物科技有限公司 | A kind of plant essence Face-protecting mask essence |
CN107823095A (en) * | 2017-12-07 | 2018-03-23 | 安徽生物肽产业研究院有限公司 | A kind of active peptide facial mask |
CN109223618A (en) * | 2018-10-31 | 2019-01-18 | 成都珂萝瑞诗化妆品有限公司 | A kind of hyaluronic acid Essence and preparation method thereof |
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CN101293929A (en) * | 2007-04-29 | 2008-10-29 | 王鹤尧 | Preparation and application of natural polypeptide medicaments derivative |
CN106137906A (en) * | 2015-04-27 | 2016-11-23 | 广州慕咖伦生物科技有限公司 | A kind of plant essence Face-protecting mask essence |
CN107823095A (en) * | 2017-12-07 | 2018-03-23 | 安徽生物肽产业研究院有限公司 | A kind of active peptide facial mask |
CN109223618A (en) * | 2018-10-31 | 2019-01-18 | 成都珂萝瑞诗化妆品有限公司 | A kind of hyaluronic acid Essence and preparation method thereof |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111588657A (en) * | 2020-06-09 | 2020-08-28 | 广州市轩颜化妆品有限公司 | Vitreous chromogen and blue copper peptide double-effect combined essence and preparation method thereof |
CN115054564A (en) * | 2021-09-28 | 2022-09-16 | 山东仟草医药科技有限公司 | Composite small-molecule active peptide whitening secondary polishing essence |
CN115054532A (en) * | 2021-09-28 | 2022-09-16 | 山东仟草医药科技有限公司 | Compound small-molecule active peptide moisturizing secondary polishing essence |
CN114948837A (en) * | 2022-04-21 | 2022-08-30 | 山东仟草医药科技有限公司 | Composite micromolecule active peptide wrinkle-removing secondary polishing essence |
CN114948785A (en) * | 2022-04-21 | 2022-08-30 | 山东仟草医药科技有限公司 | Compound small-molecule active peptide essence capable of astringing and relieving acne red and swollen and secondarily polishing |
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