CN115038517A - 反应装置及其加工方法、栓塞微球的制备设备及其制备方法 - Google Patents

反应装置及其加工方法、栓塞微球的制备设备及其制备方法 Download PDF

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CN115038517A
CN115038517A CN202080093565.2A CN202080093565A CN115038517A CN 115038517 A CN115038517 A CN 115038517A CN 202080093565 A CN202080093565 A CN 202080093565A CN 115038517 A CN115038517 A CN 115038517A
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马亚丹
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Suzhou Hengrui Hongyuan Medical Technology Co ltd
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Suzhou Hengrui Hongyuan Medical Technology Co ltd
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Priority claimed from CN202010072301.0A external-priority patent/CN112569878B/zh
Priority claimed from CN202010722636.2A external-priority patent/CN112569881B/zh
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093Microreactors, e.g. miniaturised or microfabricated reactors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006Controlling or regulating processes
    • B01J19/0013Controlling the temperature of the process
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/02Apparatus characterised by being constructed of material selected for its chemically-resistant properties
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J4/00Feed or outlet devices; Feed or outlet control devices
    • B01J4/001Feed or outlet devices as such, e.g. feeding tubes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00788Three-dimensional assemblies, i.e. the reactor comprising a form other than a stack of plates
    • B01J2219/00792One or more tube-shaped elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00851Additional features
    • B01J2219/00869Microreactors placed in parallel, on the same or on different supports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00873Heat exchange

Abstract

本发明提供了反应装置及其加工方法,其中反应装置包括主体结构层和封装层,主体结构层集成有液珠的槽,封装层叠置于所述主体结构层的一侧;主体结构层与封装层采用同种材料制成,且主体结构层的熔融温度高于封装层的熔融温度,主体结构层与封装层通过热键合方式连接。本发明反应装置具有一体化、结构稳定、强度高等优点,显著提升液珠生成的稳定性。本发明还涉及栓塞微球的制备设备及其制备方法,其通过进料系统(1)、微球生成模块(2)、固化装置(3)三大系统结合实现了自动化、标准化、可控化生产。

Description

PCT国内申请,说明书已公开。

Claims (44)

  1. PCT国内申请,权利要求书已公开。
CN202080093565.2A 2020-01-21 2020-09-21 反应装置及其加工方法、栓塞微球的制备设备及其制备方法 Pending CN115038517A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN202010072301.0A CN112569878B (zh) 2020-01-21 2020-01-21 制备粒径均一的聚乙烯醇栓塞微球的设备及其生产工艺
CN2020100723010 2020-01-21
CN2020107226362 2020-07-24
CN202010722636.2A CN112569881B (zh) 2020-07-24 2020-07-24 一种反应装置及其加工方法
PCT/CN2020/116485 WO2021147356A1 (zh) 2020-01-21 2020-09-21 反应装置及其加工方法、栓塞微球的制备设备及其制备方法

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