CN115032404A - Vaccine antibody detection card, detection system and detection method thereof - Google Patents
Vaccine antibody detection card, detection system and detection method thereof Download PDFInfo
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- CN115032404A CN115032404A CN202210655695.1A CN202210655695A CN115032404A CN 115032404 A CN115032404 A CN 115032404A CN 202210655695 A CN202210655695 A CN 202210655695A CN 115032404 A CN115032404 A CN 115032404A
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
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- G—PHYSICS
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- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00752—Type of codes bar codes
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Abstract
The invention relates to a vaccine antibody detection card, a detection system and a detection method thereof, belonging to the technical field of immunological detection, and comprising a detection card main body, wherein the inner wall of the bottom of the detection card main body is provided with a reagent strip, the top of the detection card main body is provided with a sample adding hole and an observation window, one side of the top of the detection card main body is fixedly connected with a first bar code, a glass plate is fixedly connected in the observation window, and the top of the detection card main body is provided with two groups of sealing components which have the same structure and are used for sealing the sample adding hole Automatically dripping the test agent to be detected and scanning the code operation to make the detection card body and the user perform information binding.
Description
Technical Field
The invention belongs to the technical field of immunological detection, and relates to a vaccine antibody detection card, a detection system and a detection method thereof.
Background
The vaccine is a preventive biological product for preventing and controlling the occurrence and prevalence of infectious diseases and used for human body vaccination. Biologics for vaccination include vaccines, bacterins and toxoids. Wherein the vaccine is prepared from pathogenic bacteria; the vaccine is prepared from virus, rickettsia and spirochete and is generally called vaccine. The vaccine is an automatic immune preparation for preventing infectious diseases, which is prepared by artificially attenuating and inactivating pathogenic microorganisms (such as bacteria, rickettsia, viruses and the like) and metabolites thereof or by utilizing genetic engineering and other methods. After the pathogenic bacteria without harm are inoculated, the immune system can generate certain protective substances, such as immune hormone, active physiological substances, special antibodies and the like; when the body is again exposed to such pathogenic bacteria, the immune system of the body is rapidly activated, producing specific antibodies to protect the body.
In addition, during the existing detection, mostly the detection reagent is dropped into the sample adding hole for detection through manpower, the manpower can only be suitable for a small amount of detection, a large amount of detection reagents can not be detected, and the detection reagent and the detection result are easy to confuse to cause errors of detection data.
Disclosure of Invention
In view of this, the present invention provides a vaccine antibody detection card, a detection system and a detection method thereof, in order to solve the problems in the prior art that the detection card is contaminated by external bacteria, the detection card is contaminated by the detection agent to be detected spilled from the detection card, manual detection is required, a large amount of detection cannot be performed, and the detection agent to be detected is confused with a detection result.
In order to achieve the purpose, the invention provides the following technical scheme:
a vaccine antibody detection card comprises a detection card main body, wherein a reagent strip is arranged on the inner wall of the bottom of the detection card main body, a sample adding hole and an observation window are arranged on the top of the detection card main body, a first bar code is fixedly connected to one side of the top of the detection card main body, and a glass plate is fixedly connected in the observation window;
the top of the detection card main body is provided with two groups of sealing components which have the same structure and are used for sealing the sample adding holes.
Further, the seal assembly comprises a sliding groove arranged at the top of the detection card main body, a sliding plate is connected in the sliding groove, one side of the sliding plate close to the sample adding hole is fixedly connected with a plurality of first tension springs, the other end of each first tension spring is fixedly connected with the inner wall of one side of the sliding groove, the top of the detection card main body is slidably connected with a seal plate used for sealing the sample adding hole, the bottom of the seal plate is fixedly connected with the top of the sliding plate, and a trapezoidal through hole is formed in the seal plate.
Further, the bottom fixedly connected with of detection card main part has a plurality of rubber pads, the bottom fixedly connected with magnet of detection card main part increases the detection card main part through the rubber pad and places the frictional force between the platform, avoids the detection card main part light and easily slides, leads to the sample in the sample loading hole to wait to detect reagent and spills.
A vaccine antibody detection system is used for automatically detecting the vaccine antibody detection card and comprises a workbench and a liquid storage bag positioned above the workbench, wherein a metal conveying belt is arranged at the top of the workbench, a plurality of detection card bodies are placed at the top of the metal conveying belt, the detection card bodies can be tightly adsorbed on the metal conveying belt through magnets to avoid displacement of the detection card bodies on the metal conveying belt, a first vertical plate and a second vertical plate are fixedly connected to the top of the workbench, and a sliding plate is connected between the first vertical plate and the second vertical plate in a sliding manner;
the top of the workbench is provided with an opening component for opening a sample adding hole;
the top of the sliding plate is provided with an extrusion component for extruding the liquid storage bag;
one side of second riser is equipped with the yard subassembly of sweeping that is used for sweeping the sign indicating number, and the subassembly of opening can drive simultaneously and extrude the subassembly and sweep a yard subassembly.
Further, the opening assembly comprises a first electric push rod fixedly connected to the top of the workbench, a sliding hole is formed in the top of the second vertical plate, a connecting block fixedly connected with the sliding plate is connected in the sliding hole in a sliding mode, an output shaft of the first electric push rod is fixedly connected with the bottom of the connecting block, two trapezoidal blocks are fixedly connected to the bottom of the sliding plate, and the trapezoidal blocks are matched with the trapezoidal through holes.
Further, the extrusion subassembly includes two symmetrical fixed plates of fixed connection at the sliding plate top, the fixed plate is close to a plurality of springs of one side fixedly connected with of reservoir, the splint that the other end fixedly connected with of spring and reservoir touched mutually, and the top sliding connection of the bottom of splint and sliding plate, the liquid dropping needle of sliding plate is run through to the bottom fixedly connected with of reservoir, the equal fixedly connected with trapezoidal pole in one side that first riser and second riser are close to each other, and trapezoidal pole and splint cooperate, be equipped with two holes of stepping down in the sliding plate.
Further, sweep the diaphragm that the sign indicating number subassembly includes that fixed connection keeps away from one side of first riser at the second riser, one side sliding connection of second riser has first rack, the bottom of first rack and the top of diaphragm pass through second extension spring elastic connection, one side sliding connection of second riser has the slide bar with connecting block fixed connection, the one end fixedly connected with second rack of connecting block is kept away from to the slide bar, it is connected with the pivot to rotate between second riser and the first riser, the fixed cover of outer wall of pivot is equipped with first sign indicating number ware, the one end of pivot is rotated and is run through second riser and fixedly connected with gear, and the gear meshes with second rack and first rack mutually respectively.
Further, one side fixedly connected with second bar code that the reservoir is close to first bar code ware can bind user's information and second bar code through the second bar code to bind with later stage testing result and second bar code, thereby can be clear link testing result and user, avoid testing result and user information to obscure.
Further, one side of the top of the workbench is fixedly connected with an L-shaped frame, the inner wall of the top of the L-shaped frame is fixedly connected with a second code scanner and a camera, the inner wall of one side of the L-shaped frame is fixedly connected with a second electric push rod, one side of the workbench, which is far away from the L-shaped frame, is provided with a collecting box, a rotating shaft is rotationally connected in the collecting box, a rotating cover is fixedly sleeved on the outer wall of the rotating shaft, two torsional springs are sleeved on the outer wall of the rotating shaft, one ends, which are close to each other, of the two torsional springs are fixedly connected with the rotating cover, the other end of the torsional springs is fixedly connected with the inner wall of one side of the collecting box, a detection card main body is positioned below the L-shaped frame, a test agent to be detected and a reagent strip react at the moment, the camera obtains a detection result through shooting of an observation window, the second code scanner scans the first bar code, and transmits information to a control terminal, the control terminal binds the detection result with the corresponding first bar code and the second bar code, so that the detection result of the user can be obtained, and the data confusion phenomenon occurring in the process of detecting a large number of data is avoided.
The detection method of the vaccine antibody detection system comprises the following steps:
s1, placing the plurality of detection card bodies on a metal conveyor belt, placing the liquid storage bag on a sliding plate, penetrating a liquid dropping needle through the sliding plate, clamping the liquid storage bag preliminarily by the two clamping plates under the elastic action of a spring, starting the metal conveyor belt, and conveying the detection card bodies to the left side by the metal conveyor belt;
s2, when the sample adding hole is located below the liquid dropping needle, the metal conveying belt stops running, the first electric push rod is started, the output shaft of the first electric push rod drives the sliding plate to move downwards through the connecting block, the sliding plate drives the liquid storage bag and the liquid dropping needle to move downwards, the connecting block can drive the sliding rod and the second rack to move downwards for a certain distance along with the downward movement of the sliding plate, the second rack is not meshed with the gear at the moment, and then the sliding plate drives the liquid storage bag to move downwards for a certain distance, the first code scanner can just scan the second bar code carrying user information, and the first code scanner transmits the scanning information to a control terminal (not shown in the figure);
s3, continuing to drive the sliding plate and the second rack to move downwards by the output shaft of the first electric push rod, extending the trapezoidal block into the trapezoidal through hole, enabling the sealing plate and the sliding plate to move outwards by the matching of the trapezoidal block and the trapezoidal through hole, starting to stretch the first tension spring, releasing the sealing of the sealing plate on the sample adding hole, continuing to move downwards by the sliding plate, extending the liquid dropping needle into the sample adding hole, enabling the inclined surface of the trapezoidal rod to be in contact with the clamping plate in the downward moving process of the sliding plate, pushing the clamping plate to move towards the middle by the inclined surface of the trapezoidal rod, and further enabling the clamping plate to extrude the liquid storage bag, wherein the test agent to be tested in the liquid storage bag is dropped into the sample adding hole through the liquid dropping needle and is dropped on the reagent strip for detection;
s4, when the sliding plate moves downwards to finish the dropping operation of the reagent to be detected, the connecting block drives the second rack to move downwards through the sliding rod, the second rack is meshed with the gear at the moment, the second rack drives the gear, the rotating shaft and the first code scanner to rotate 90 degrees anticlockwise, the first code scanner can scan the first code, the first code scanner transmits code scanning information to the control terminal, the control terminal performs information binding on the corresponding first code and the second code, and when the gear rotates 90 degrees anticlockwise, the gear drives the first rack to slide upwards and stretch the second tension spring;
s5, when the test agent to be detected in the liquid storage bag is dripped completely and the code scanning is completed, starting a first electric push rod, driving a second rack, a sliding plate and a sliding rod to reset upwards through a connecting block by an output shaft of the first electric push rod, re-sealing a sample feeding hole under the tension of a first tension spring after the sealing plate loses the thrust of a trapezoidal block, reversely rotating a gear under the tension of a second tension spring after the second rack is disengaged, and keeping the first code scanner in a horizontal state again;
s6, with the continuous conveying of the metal conveying belt, the main body of the detection card is located below the L-shaped frame after being conveyed for 15 minutes, the reaction of the test agent to be detected and the reagent strip is finished, the camera obtains the detection result through shooting the observation window, the second code scanner scans the first bar code, the second code scanner and the camera transmit information to the control terminal, the control terminal binds the detection result with the corresponding first bar code and the second bar code, the detection result of the user can be obtained, and the data confusion phenomenon occurring in the process of mass detection is avoided.
The invention has the beneficial effects that:
1. the top of the detection card main body of the vaccine antibody detection card is slidably connected with two closing plates for closing sample adding holes, trapezoidal through holes are formed in the closing plates, the bottom of each closing plate is fixedly connected with a sliding plate which is slidably connected with a sliding groove, one side, close to the sample adding holes, of each sliding plate is fixedly connected with a plurality of first tension springs, the other ends of the first tension springs are fixedly connected with the inner wall of one side of the sliding groove, under the action of the tension force of the first tension springs on the sliding plates, after the injection of a reagent to be detected into the sample adding holes is finished, the closing plates re-close the sample adding holes under the tension force of the first tension springs, the reagent to be detected is prevented from being polluted by external bacteria during waiting, and the pollution caused by the fact that the reagent to be detected is scattered is avoided;
2. the outer wall of the rotating shaft of the vaccine antibody detection system is fixedly sleeved with a first bar code, one side of the liquid storage bag is fixedly connected with a second bar code, the second bar code and the first bar code are scanned by the first bar code, the scanned data of the first bar code are transmitted to a control terminal, the first bar code and the second bar code can be bound by the control terminal, and then the information of a user can be bound with a detection card body, so that the detection result of the corresponding user can be conveniently obtained from an observation window in the later period, and the detection result distortion caused by the fact that the detection data does not correspond to the information of the user is avoided;
3. this a vaccine antibody detecting system's fixed plate is close to a plurality of springs of one side fixedly connected with of reservoir, the other end fixedly connected with splint of spring, and the bottom of splint and the top sliding connection of sliding plate, the equal fixedly connected with ladder-shaped pole in one side that first riser and second riser are close to each other, and the ladder-shaped pole cooperatees with splint, when the sliding plate drives splint and moves down, the inclined plane and the splint of ladder-shaped pole touch each other, splint extrude the reservoir under the effect of ladder-shaped pole, and then can accomplish and wait to detect in the reservoir that the reagent instils into sample application hole, need not manual operation, reduce medical staff's intensity of labour and ensure medical staff's safety again.
4. This teenagers 'growth language pronunciation correction education device based on internet's two trapezoidal pieces of bottom fixedly connected with, and trapezoidal piece and trapezoidal through-hole cooperate, when the sliding plate drives trapezoidal piece and moves down, trapezoidal piece extends to trapezoidal through-hole in, can open sample application of sample hole automatically through the cooperation of trapezoidal through-hole and trapezoidal piece and make things convenient for the later stage automatic will examine the testing agent and instil into sample application of sample hole in.
The sample feeding hole can be closed in time through the matching of the closing plate, the sliding plate and the first tension spring, so that the reagent to be detected is prevented from being polluted by external bacteria during waiting, the pollution caused by the sprinkling of the reagent to be detected can be avoided, in addition, the opening of the sample feeding hole, the automatic dripping of the reagent to be detected and the code scanning operation can be sequentially completed by starting the first electric push rod to drive the connecting block to move up and down, the simplicity and convenience are realized, the detection task can be rapidly completed, and meanwhile, the information binding between the detection card body and a user can be realized.
Drawings
For the purposes of promoting a better understanding of the objects, aspects and advantages of the invention, reference will now be made to the following detailed description taken in conjunction with the accompanying drawings in which:
FIG. 1 is a three-dimensional view of a vaccine antibody detection card according to the present invention;
FIG. 2 is a three-dimensional sectional view of a vaccine antibody detection card according to the present invention;
FIG. 3 is a three-dimensional view of a vaccine antibody detection system according to the present invention;
FIG. 4 is a three-dimensional view from a first perspective of a vaccine antibody detection system according to the present invention;
FIG. 5 is a three-dimensional view from a second perspective of a vaccine antibody detection system according to the present invention;
FIG. 6 is a three-dimensional view of the extrusion assembly of a vaccine antibody detection system according to the present invention;
FIG. 7 is a three-dimensional view of a code scanning assembly of the vaccine antibody detection system according to the present invention;
FIG. 8 is a front view of a vaccine antibody detection system according to the present invention in example two;
fig. 9 is a front sectional view of the collection box of the front view of the vaccine antibody detection system according to the second embodiment of the present invention.
Reference numerals: 1. detecting a card main body; 2. a sample addition well; 3. an observation window; 4. a reagent strip; 5. a first bar code; 6. a magnet; 7. a rubber pad; 8. a glass plate; 9. a chute; 10. a closing plate; 11. a slide plate; 12. a first tension spring; 13. a trapezoidal through hole; 14. a work table; 15. a metal conveyor belt; 16. a first vertical plate; 17. a second vertical plate; 18. a sliding plate; 19. a reservoir; 20. a second bar code; 21. a slide hole; 22. connecting blocks; 23. a first electric push rod; 24. a trapezoidal block; 25. a drip needle; 26. a fixing plate; 27. a splint; 28. a spring; 29. a hole of abdication; 30. a trapezoidal bar; 31. a rotating shaft; 32. a first code scanner; 33. a gear; 34. a transverse plate; 35. a first rack; 36. a second tension spring; 37. a slide bar; 38. a second rack; 39. an L-shaped frame; 40. a second electric push rod; 41. a collection box; 42. a rotating shaft; 43. rotating the cover; 44. a torsion spring; 45. a second code scanner; 46. a camera is provided.
Detailed Description
The embodiments of the present invention are described below with reference to specific embodiments, and other advantages and effects of the present invention will be easily understood by those skilled in the art from the disclosure of the present specification. The invention is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present invention. It should be noted that the drawings provided in the following embodiments are only for illustrating the basic idea of the present invention in a schematic way, and the features in the following embodiments and embodiments may be combined with each other without conflict.
Wherein the showings are for the purpose of illustrating the invention only and not for the purpose of limiting the same, and in which there is shown by way of illustration only and not in the drawings in which there is no intention to limit the invention thereto; to better illustrate the embodiments of the present invention, some parts of the drawings may be omitted, enlarged or reduced, and do not represent the size of an actual product; it will be understood by those skilled in the art that certain well-known structures in the drawings and descriptions thereof may be omitted.
The same or similar reference numerals in the drawings of the embodiments of the present invention correspond to the same or similar components; in the description of the present invention, it should be understood that if there is an orientation or positional relationship indicated by terms such as "upper", "lower", "left", "right", "front", "rear", etc., based on the orientation or positional relationship shown in the drawings, it is only for convenience of description and simplification of description, but it is not an indication or suggestion that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes, and are not to be construed as limiting the present invention, and the specific meaning of the terms may be understood by those skilled in the art according to specific situations.
Example one
Referring to fig. 1-2, a vaccine antibody detection card, including detection card main part 1, the bottom inner wall of detection card main part 1 is equipped with reagent strip 4, the top of detection card main part 1 is equipped with sample application hole 2 and observation window 3, top one side fixedly connected with first bar code 5 of detection card main part 1, there is glass plate 8 through bolt fixedly connected with in the observation window 3, the top of detection card main part 1 is equipped with two sets of closed components that are used for closing sample application hole 2 that have the same structure, a plurality of rubber pads 7 of bolt fixedly connected with are passed through to the bottom of detection card main part 1, there is magnet 6 through bolt fixedly connected with in the bottom of detection card main part 1, increase the frictional force between detection card main part 1 and the platform of placing through rubber pad 7, avoid detection card main part 1 to slide easily, lead to the reagent that detects in sample application hole 2 to spill.
In the invention, the sealing component comprises a chute 9 arranged at the top of the detection card main body 1, a sliding plate 11 is connected in the chute 9 in a sliding way, one side of the sliding plate 11 close to the sample adding hole 2 is fixedly connected with a plurality of first tension springs 12, the other end of the first tension spring 12 is fixedly connected with the inner wall of one side of the chute 9, the top of the detection card main body 1 is slidably connected with a closing plate 10 for closing the sample adding hole 2, the bottom of the closing plate 10 is fixedly connected with the top of the sliding plate 11 through a bolt, a trapezoidal through hole 13 is arranged in the closing plate 10, under the action of the tension of the first tension spring 12 on the sliding plate 11, after the reagent to be detected is injected into the sample adding hole 2, the closing plate 10 closes the sample adding hole 2 again under the tension of the first tension spring 12, so that the reagent to be detected is prevented from being polluted by external bacteria during waiting, and the pollution caused by the spilling of the reagent to be detected can be avoided.
Referring to fig. 3-7, a vaccine antibody detection system for automatic detection of the vaccine antibody detection card as described above comprises a workbench 14 and a reservoir 19 located above the workbench 14, a metal conveyor belt 15 is provided on the top of the workbench 14, a plurality of detection card bodies 1 are placed on the top of the metal conveyor belt 15, the detection card bodies 1 can be tightly attached to the metal conveyor belt 15 by a magnet 6 to prevent the detection card bodies 1 from displacing on the metal conveyor belt 15, a first vertical plate 16 and a second vertical plate 17 are fixedly connected to the top of the workbench 14 by bolts, a sliding plate 18 is slidably connected between the first vertical plate 16 and the second vertical plate 17, an opening component for opening a sample adding hole 2 is provided on the top of the workbench 14, a pressing component for pressing the reservoir 19 is provided on the top of the sliding plate 18, a code scanning component for scanning codes is provided on one side of the second vertical plate 17, the opening assembly can drive the extrusion assembly and the code scanning assembly at the same time, the liquid storage bag 19 is close to the second bar code 20 of one side fixedly connected with of the first code scanning device 32, the information of the user can be bound with the second bar code 20 through the second bar code 20, and the detection result is bound with the second bar code 20, so that the detection result can be clearly linked with the user, and the confusion of the detection result and the user information is avoided.
According to the invention, the opening component comprises a first electric push rod 23 fixedly connected to the top of the workbench 14 through a bolt, a sliding hole 21 is formed in the top of the second vertical plate 17, a connecting block 22 fixedly connected with the sliding plate 18 is connected in the sliding hole 21 in a sliding manner, an output shaft of the first electric push rod 23 is fixedly connected with the bottom of the connecting block 22 through a bolt, two trapezoidal blocks 24 are fixedly connected to the bottom of the sliding plate 18 through bolts, the trapezoidal blocks 24 are matched with the trapezoidal through holes 13, when the sliding plate 18 drives the trapezoidal blocks 24 to move downwards, the trapezoidal blocks 24 extend into the trapezoidal through holes 13, and the sample adding holes 2 can be automatically opened through the matching of the trapezoidal through holes 13 and the trapezoidal blocks 24, so that a test agent to be detected can be automatically dripped into the sample adding holes 2 in the later period.
In the invention, the extrusion assembly comprises two symmetrical fixed plates 26 fixedly connected to the top of the sliding plate 18 through bolts, one side of the fixed plate 26 close to the reservoir 19 is fixedly connected with a plurality of springs 28, the other end of each spring 28 is fixedly connected with a clamping plate 27 touching the reservoir 19, the bottom of each clamping plate 27 is slidably connected with the top of the sliding plate 18, the bottom of the reservoir 19 is fixedly connected with a drip needle 25 penetrating through the sliding plate 18, one side of the first vertical plate 16 and one side of the second vertical plate 17 close to each other are fixedly connected with a trapezoidal rod 30 through bolts, the trapezoidal rods 30 are matched with the clamping plates 27, two abdicating holes 29 are arranged in the sliding plate 18, when the sliding plate 18 drives the clamping plates 27 to move downwards, the inclined surfaces of the trapezoidal rods 30 touch the clamping plates 27, the clamping plates 27 extrude the reservoir 19 under the action of the trapezoidal rods 30, and further can finish dripping the reagent to be detected in the reservoir 19 into the sample adding hole 2, the manual operation is not needed, the labor intensity of the medical staff is reduced, and the safety of the medical staff is guaranteed.
In the invention, the code scanning component comprises a transverse plate 34 fixedly connected to one side of the second vertical plate 17 far away from the first vertical plate 16 through a bolt, one side of the second vertical plate 17 is slidably connected with a first rack 35, the bottom end of the first rack 35 is elastically connected with the top of the transverse plate 34 through a second tension spring 36, one side of the second vertical plate 17 is slidably connected with a slide bar 37 fixedly connected with the connecting block 22, one end of the slide bar 37 far away from the connecting block 22 is fixedly connected with a second rack 38 through a bolt, a rotating shaft 31 is rotatably connected between the second vertical plate 17 and the first vertical plate 16, the outer wall of the rotating shaft 31 is fixedly sleeved with a first code scanner 32, one end of the rotating shaft 31 rotatably penetrates through the second vertical plate 17 and is fixedly connected with a gear 33, the gear 33 is respectively meshed with the second rack 38 and the first rack 35, the first bar code 5 and the second bar code 20 can be bound through a control terminal, and further the information of a user can be bound with the detection card body 1, therefore, the detection result of the corresponding user can be conveniently obtained from the observation window 3 in the later stage, and the detection result distortion caused by the fact that the detection data does not correspond to the user information is avoided.
Example two
As a further improvement of the previous embodiment, referring to fig. 1-2, the vaccine antibody detection card comprises a detection card body 1, a reagent strip 4 is disposed on the inner wall of the bottom of the detection card body 1, a sample application hole 2 and an observation window 3 are disposed on the top of the detection card body 1, a first bar code 5 is fixedly connected to one side of the top of the detection card body 1, a glass plate 8 is fixedly connected to the inside of the observation window 3 through bolts, two sets of sealing components having the same structure and used for sealing the sample application hole 2 are disposed on the top of the detection card body 1, a plurality of rubber pads 7 are fixedly connected to the bottom of the detection card body 1 through bolts, a magnet 6 is fixedly connected to the bottom of the detection card body 1 through bolts, increase the frictional force between detection card main part 1 and the platform of placing through rubber pad 7, avoid detecting card main part 1 and slide easily, lead to the sample to wait to detect reagent in the sample application hole 2 and spill.
In the invention, the sealing component comprises a sliding chute 9 arranged at the top of the detection card main body 1, a sliding plate 11 is connected in the sliding chute 9 in a sliding way, one side of the sliding plate 11 close to the sample adding hole 2 is fixedly connected with a plurality of first tension springs 12, the other end of the first tension spring 12 is fixedly connected with the inner wall of one side of the chute 9, the top of the detection card main body 1 is slidably connected with a closing plate 10 for closing the sample adding hole 2, the bottom of the closing plate 10 is fixedly connected with the top of the sliding plate 11 through a bolt, a trapezoidal through hole 13 is arranged in the closing plate 10, under the action of the tension of the first tension spring 12 on the sliding plate 11, after the reagent to be detected is injected into the sample adding hole 2, the closing plate 10 closes the sample adding hole 2 again under the tension of the first tension spring 12, so that the reagent to be detected is prevented from being polluted by external bacteria during waiting, and the pollution caused by the spilling of the reagent to be detected can be avoided.
Referring to fig. 3-9, a vaccine antibody detection system for automatically detecting the vaccine antibody detection card as described above, comprising a workbench 14 and a reservoir 19 located above the workbench 14, wherein a metal conveyor belt 15 is provided on the top of the workbench 14, a plurality of detection card bodies 1 are placed on the top of the metal conveyor belt 15, the detection card bodies 1 can be tightly adsorbed on the metal conveyor belt 15 by a magnet 6 to prevent the detection card bodies 1 from displacement on the metal conveyor belt 15, a first vertical plate 16 and a second vertical plate 17 are fixedly connected to the top of the workbench 14 by bolts, a sliding plate 18 is slidably connected between the first vertical plate 16 and the second vertical plate 17, an opening component for opening a sample application hole 2 is provided on the top of the workbench 14, a pressing component for pressing the reservoir 19 is provided on the top of the sliding plate 18, a code scanning component for scanning a code is provided on one side of the second vertical plate 17, the opening assembly can drive the extrusion assembly and the code scanning assembly at the same time, the liquid storage bag 19 is close to the second bar code 20 of one side fixedly connected with of the first code scanning device 32, the information of the user can be bound with the second bar code 20 through the second bar code 20, and the detection result is bound with the second bar code 20, so that the detection result can be clearly linked with the user, and the confusion of the detection result and the user information is avoided.
According to the invention, the opening assembly comprises a first electric push rod 23 fixedly connected to the top of the workbench 14 through a bolt, a sliding hole 21 is formed in the top of the second vertical plate 17, a connecting block 22 fixedly connected with the sliding plate 18 is connected in the sliding hole 21 in a sliding mode, an output shaft of the first electric push rod 23 is fixedly connected with the bottom of the connecting block 22 through a bolt, two trapezoidal blocks 24 are fixedly connected to the bottom of the sliding plate 18 through bolts, the trapezoidal blocks 24 are matched with the trapezoidal through holes 13, when the sliding plate 18 drives the trapezoidal blocks 24 to move downwards, the trapezoidal blocks 24 extend into the trapezoidal through holes 13, and the sample adding holes 2 can be automatically opened through the matching of the trapezoidal through holes 13 and the trapezoidal blocks 24, so that a test agent to be tested can be automatically dripped into the sample adding holes 2 in the later period.
In the invention, the extrusion assembly comprises two symmetrical fixed plates 26 fixedly connected to the top of the sliding plate 18 through bolts, one side of the fixed plate 26 close to the reservoir 19 is fixedly connected with a plurality of springs 28, the other end of each spring 28 is fixedly connected with a clamping plate 27 touching the reservoir 19, the bottom of each clamping plate 27 is slidably connected with the top of the sliding plate 18, the bottom of the reservoir 19 is fixedly connected with a drip needle 25 penetrating through the sliding plate 18, one side of the first vertical plate 16 and one side of the second vertical plate 17 close to each other are fixedly connected with a trapezoidal rod 30 through bolts, the trapezoidal rods 30 are matched with the clamping plates 27, two abdicating holes 29 are arranged in the sliding plate 18, when the sliding plate 18 drives the clamping plates 27 to move downwards, the inclined surfaces of the trapezoidal rods 30 touch the clamping plates 27, the clamping plates 27 extrude the reservoir 19 under the action of the trapezoidal rods 30, and further can finish dripping the reagent to be detected in the reservoir 19 into the sample adding hole 2, the manual operation is not needed, the labor intensity of the medical staff is reduced, and the safety of the medical staff is guaranteed.
In the invention, the code scanning component comprises a transverse plate 34 fixedly connected to one side of the second vertical plate 17 far away from the first vertical plate 16 through a bolt, one side of the second vertical plate 17 is slidably connected with a first rack 35, the bottom end of the first rack 35 is elastically connected with the top of the transverse plate 34 through a second tension spring 36, one side of the second vertical plate 17 is slidably connected with a slide bar 37 fixedly connected with the connecting block 22, one end of the slide bar 37 far away from the connecting block 22 is fixedly connected with a second rack 38 through a bolt, a rotating shaft 31 is rotatably connected between the second vertical plate 17 and the first vertical plate 16, the outer wall of the rotating shaft 31 is fixedly sleeved with a first code scanner 32, one end of the rotating shaft 31 rotatably penetrates through the second vertical plate 17 and is fixedly connected with a gear 33, the gear 33 is respectively meshed with the second rack 38 and the first rack 35, the first bar code 5 and the second bar code 20 can be bound through a control terminal, and further the information of a user can be bound with the detection card body 1, therefore, the detection result of the corresponding user can be conveniently obtained from the observation window 3 in the later stage, and the detection result distortion caused by the fact that the detection data does not correspond to the user information is avoided.
In the invention, an L-shaped frame 39 is fixedly connected with one side of the top of a workbench 14 through a bolt, a second code scanner 45 and a camera 46 are fixedly connected with the inner wall of the top of the L-shaped frame 39 through a bolt, a second electric push rod 40 is fixedly connected with the inner wall of one side of the L-shaped frame 39 through a bolt, a collecting box 41 is arranged on one side of the workbench 14 far away from the L-shaped frame 39, a rotating shaft 42 is connected in the collecting box 41 in a rotating manner, a rotating cover 43 is fixedly sleeved on the outer wall of the rotating shaft 42, two torsion springs 44 are sleeved on the outer wall of the rotating shaft 42, the mutually close ends of the two torsion springs 44 are fixedly connected with the rotating cover 43, the other end of the torsion spring 44 is fixedly connected with the inner wall of one side of the collecting box 41, a detection card main body 1 is positioned below the L-shaped frame 39, at the moment, a test agent to be detected and a reagent strip 4 are reacted, the camera 46 obtains a detection result through shooting of an observation window 3, and the second code scanner 45 scans a first bar code 5, the second bar code scanner 45 and the camera 46 transmit information to the control terminal, and the control terminal binds the detection result with the corresponding first bar code 5 and the second bar code 20, so that the detection result of the user can be obtained, and the data confusion phenomenon occurring in a large amount of detection is avoided.
The advantages of the second embodiment over the first embodiment are: bolt fixedly connected with L type frame 39 is passed through to top one side of workstation 14, bolt fixedly connected with second bar code collector 45 and camera 46 are passed through to the top inner wall of L type frame 39, bolt fixedly connected with second electric putter 40 is passed through to one side inner wall of L type frame 39, one side that L type frame 39 was kept away from to workstation 14 is equipped with collecting box 41, 41 internal rotation of collecting box is connected with axis of rotation 42, the outer wall fixed cover of axis of rotation 42 is equipped with rotation lid 43, the outer wall cover of axis of rotation 42 is equipped with two torsional springs 44, the one end that two torsional springs 44 are close to each other all with rotation lid 43 fixed connection, the other end of torsional spring 44 and one side inner wall fixed connection of collecting box 41.
A detection method of a vaccine antibody detection system comprises the following steps:
s1, placing a plurality of detection card main bodies 1 on the metal conveyor belt 15, placing the liquid storage bag 19 on the sliding plate 18, enabling the liquid dropping needle 25 to penetrate through the sliding plate 18, enabling the two clamping plates 27 to preliminarily clamp the liquid storage bag 19 under the elastic action of the spring 28, starting the metal conveyor belt 15, and enabling the metal conveyor belt 15 to convey the detection card main bodies 1 to the left side;
s2, when the sample adding hole 2 is located below the liquid dropping needle 25, the metal conveyor belt 15 stops running, the first electric push rod 23 is started, the output shaft of the first electric push rod 23 drives the sliding plate 18 to move downwards through the connecting block 22, the sliding plate 18 drives the liquid storage bag 19 and the liquid dropping needle 25 to move downwards, the connecting block 22 can drive the sliding rod 37 and the second rack 38 to move downwards for a certain distance along with the downward movement of the sliding plate 18, at the moment, the second rack 38 is not meshed with the gear 33, and further, when the sliding plate 18 drives the liquid storage bag 19 to move downwards for a certain distance, the first code scanner 32 can just scan the second rack 20 carrying user information, and the first code scanner 32 transmits the scanning information to the control terminal and is not shown in the drawing;
s3, continuing to drive the sliding plate 18 and the second rack 38 to move downwards by the output shaft of the first electric push rod 23, extending the trapezoidal block 24 into the trapezoidal through hole 13, enabling the closing plate 10 and the sliding plate 11 to move outwards by the matching of the trapezoidal block 24 and the trapezoidal through hole 13, starting to stretch the first tension spring 12, releasing the closing of the closing plate 10 on the sample adding hole 2, continuing to move downwards by the sliding plate 18, enabling the dropping needle 25 to extend into the sample adding hole 2, enabling the inclined surface of the trapezoidal rod 30 to be in contact with the clamping plate 27 in the downward movement process of the sliding plate 18, enabling the clamping plate 27 to move downwards towards the middle under the pushing of the inclined surface of the trapezoidal rod 30, and further enabling the clamping plate 27 to extrude the liquid storage bag 19, enabling the test agent to be tested in the liquid storage bag 19 to be dropped into the sample adding hole 2 through the dropping needle 25 and to be detected on the reagent strip 4;
s4, when the sliding plate 18 moves downwards to finish the dropping operation of the reagent to be detected, the connecting block 22 drives the second rack 38 to move downwards through the sliding rod 37, at the moment, the second rack 38 starts to be meshed with the gear 33, the second rack 38 drives the gear 33, the rotating shaft 31 and the first code scanner 32 to rotate 90 degrees anticlockwise, the first code scanner 32 can scan the first code 5, the first code scanner 32 transmits code scanning information to the control terminal, the control terminal binds the corresponding first code 5 and the second code 20, and when the gear 33 rotates 90 degrees anticlockwise, the gear 33 drives the first rack 35 to slide upwards and stretch the second tension spring 36;
s5, when the reagent to be detected in the liquid storage bag 19 is dripped into the liquid storage bag and the code scanning is finished, the first electric push rod 23 is started, the output shaft of the first electric push rod 23 drives the second rack 38, the sliding plate 18 and the sliding rod 37 to reset upwards through the connecting block 22, the sealing plate 10 closes the sample adding hole 2 again under the tension of the first tension spring 12 after losing the thrust of the trapezoidal block 24, the gear 33 rotates reversely under the tension of the second tension spring 36 after the second rack 38 is disengaged, and the first code scanner 32 is in a horizontal state again;
s6, with the continuous conveying of the metal conveying belt 15, the detection card body 1 is located below the L-shaped frame 39 after being conveyed for 15 minutes, at the moment, the reaction of the test agent to be detected and the reagent strip 4 is finished, the camera 46 obtains the detection result through the shooting of the observation window 3, the second code scanner 45 scans the first bar code 5, the second code scanner 45 and the camera 46 transmit information to the control terminal, the control terminal binds the detection result with the corresponding first bar code 5 and the second bar code 20, the detection result of the user can be obtained, and the data confusion phenomenon occurring in the process of mass detection is avoided.
However, the working principle and wiring method of the second scanner 45, the camera 46, the second electric putter 40, the first electric putter 23 and the first scanner 32 are well known to those skilled in the art, and will not be described herein, and those skilled in the art can make any choice according to their needs or convenience.
Finally, the above embodiments are only intended to illustrate the technical solutions of the present invention and not to limit the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, it will be understood by those skilled in the art that modifications or equivalent substitutions may be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions, and all of them should be covered by the claims of the present invention.
Claims (10)
1. A vaccine antibody detection card comprises a detection card main body (1), wherein a reagent strip (4) is arranged on the inner wall of the bottom of the detection card main body (1), and a sample adding hole (2) and an observation window (3) are arranged on the top of the detection card main body (1), and is characterized in that a first bar code (5) is fixedly connected to one side of the top of the detection card main body (1), and a glass plate (8) is fixedly connected in the observation window (3);
the top of the detection card main body (1) is provided with two groups of sealing components which have the same structure and are used for sealing the sample adding holes (2).
2. The vaccine antibody detection card according to claim 1, wherein the sealing component comprises a sliding groove (9) arranged at the top of the detection card main body (1), a sliding plate (11) is slidably connected in the sliding groove (9), one side of the sliding plate (11) close to the sample adding hole (2) is fixedly connected with a plurality of first tension springs (12), the other end of each first tension spring (12) is fixedly connected with the inner wall of one side of the sliding groove (9), the top of the detection card main body (1) is slidably connected with a sealing plate (10) for sealing the sample adding hole (2), the bottom of the sealing plate (10) is fixedly connected with the top of the sliding plate (11), and a trapezoidal through hole (13) is arranged in the sealing plate (10).
3. The vaccine antibody detection card according to claim 1, wherein a plurality of rubber pads (7) are fixedly connected to the bottom of the detection card body (1), and a magnet (6) is fixedly connected to the bottom of the detection card body (1).
4. A vaccine antibody detection system for automatically detecting the vaccine antibody detection card according to any one of claims 1 to 3, which comprises a workbench (14) and a liquid storage bag (19) positioned above the workbench (14), wherein a metal conveyor belt (15) is arranged on the top of the workbench (14), a plurality of detection card bodies (1) are placed on the top of the metal conveyor belt (15), a first vertical plate (16) and a second vertical plate (17) are fixedly connected to the top of the workbench (14), and a sliding plate (18) is slidably connected between the first vertical plate (16) and the second vertical plate (17);
the top of the workbench (14) is provided with an opening component for opening the sample adding hole (2);
the top of the sliding plate (18) is provided with a squeezing component for squeezing the liquid storage bag (19);
one side of second riser (17) is equipped with the yard subassembly of sweeping that is used for sweeping the sign indicating number, and the subassembly of opening can drive the extrusion subassembly simultaneously and sweep a yard subassembly.
5. The vaccine antibody detection system according to claim 4, wherein the opening component comprises a first electric push rod (23) fixedly connected to the top of the workbench (14), the top of the second vertical plate (17) is provided with a sliding hole (21), a connecting block (22) fixedly connected with the sliding plate (18) is slidably connected in the sliding hole (21), an output shaft of the first electric push rod (23) is fixedly connected with the bottom of the connecting block (22), two trapezoidal blocks (24) are fixedly connected to the bottom of the sliding plate (18), and the trapezoidal blocks (24) are matched with the trapezoidal through holes (13).
6. The vaccine antibody detection system according to claim 4, wherein the pressing assembly comprises two symmetrical fixed plates (26) fixedly connected to the top of the sliding plate (18), one side of the fixing plate (26) close to the liquid storage bag (19) is fixedly connected with a plurality of springs (28), the other end of the spring (28) is fixedly connected with a splint (27) which is in contact with the liquid storage bag (19), the bottom of the splint (27) is connected with the top of the sliding plate (18) in a sliding way, the bottom of the liquid storage bag (19) is fixedly connected with a drip needle (25) which penetrates through the sliding plate (18), the sides of the first vertical plate (16) and the second vertical plate (17) close to each other are fixedly connected with trapezoidal rods (30), the trapezoidal rod (30) is matched with the clamping plate (27), and two abdicating holes (29) are arranged in the sliding plate (18).
7. The vaccine antibody detection system according to claim 4, wherein the code scanning component comprises a transverse plate (34) fixedly connected to one side of the second vertical plate (17) far away from the first vertical plate (16), a first rack (35) is slidably connected to one side of the second vertical plate (17), the bottom end of the first rack (35) is elastically connected to the top of the transverse plate (34) through a second tension spring (36), a sliding rod (37) fixedly connected to the connecting block (22) is slidably connected to one side of the second vertical plate (17), a second rack (38) is fixedly connected to one end of the sliding rod (37) far away from the connecting block (22), and a rotating shaft (31) is rotatably connected between the second vertical plate (17) and the first vertical plate (16).
8. The vaccine antibody detection system according to claim 7, wherein the code scanning assembly further comprises a first code scanner (32) fixedly sleeved on the outer wall of the rotating shaft (31), one end of the rotating shaft (31) is rotatably penetrated through the second vertical plate (17) and is fixedly connected with a gear (33), the gear (33) is respectively engaged with the second rack (38) and the first rack (35), and the side of the reservoir (19) close to the first code scanner (32) is fixedly connected with the second code scanner (20).
9. The vaccine antibody detection system according to claim 4, wherein an L-shaped frame (39) is fixedly connected to one side of the top of the workbench (14), the inner wall of the top part of the L-shaped frame (39) is fixedly connected with a second code scanner (45) and a camera (46), a second electric push rod (40) is fixedly connected with the inner wall of one side of the L-shaped frame (39), a collecting box (41) is arranged on one side of the workbench (14) far away from the L-shaped frame (39), a rotating shaft (42) is rotatably connected in the collecting box (41), a rotating cover (43) is fixedly sleeved on the outer wall of the rotating shaft (42), two torsion springs (44) are sleeved on the outer wall of the rotating shaft (42), one ends of the two torsion springs (44) close to each other are fixedly connected with a rotating cover (43), the other end of the torsion spring (44) is fixedly connected with the inner wall of one side of the collecting box (41).
10. The method for detecting the vaccine antibody detection system according to any one of claims 5 to 9, comprising the steps of:
s1, placing a plurality of detection card main bodies (1) on a metal conveying belt (15), placing a liquid storage bag (19) on a sliding plate (18), enabling a dripping needle (25) to penetrate through the sliding plate (18), enabling two clamping plates (27) to preliminarily clamp the liquid storage bag (19) under the elastic action of a spring (28), starting the metal conveying belt (15), and conveying the detection card main bodies (1) to the left side through the metal conveying belt (15);
s2, when the sample adding hole (2) is located below the drip needle (25), the metal conveyor belt (15) stops running, the first electric push rod (23) is started, an output shaft of the first electric push rod (23) drives the sliding plate (18) to move downwards through the connecting block (22), the sliding plate (18) drives the liquid storage bag (19) and the drip needle (25) to move downwards, the connecting block (22) can drive the sliding rod (37) and the second rack (38) to move downwards for a certain distance along with the downward movement of the sliding plate (18), the second rack (38) is not meshed with the gear (33), and further when the sliding plate (18) drives the liquid storage bag (19) to move downwards for a certain distance, the first code scanner (32) can just scan the second bar code (20) carrying user information, and transmits scanning information to the control terminal;
s3, continuing to drive the sliding plate (18) and the second rack (38) to move downwards by the output shaft of the first electric push rod (23), extending the trapezoidal block (24) into the trapezoidal through hole (13), enabling the closing plate (10) and the sliding plate (11) to move outwards by the matching of the trapezoidal block (24) and the trapezoidal through hole (13), starting to stretch the first tension spring (12), releasing the closing of the closing plate (10) on the sample adding hole (2), continuing to move downwards by the sliding plate (18), extending the dripping needle (25) into the sample adding hole (2), contacting the inclined plane of the trapezoidal rod (30) with the clamping plate (27) in the downward moving process of the sliding plate (18), pushing the clamping plate (27) to move downwards to the middle by the inclined plane of the trapezoidal rod (30), and further extruding the liquid storage bag (19) by the clamping plate (27), dripping the test agent in the liquid storage bag (19) into the sample adding hole (2) through the dripping needle (25), and the reagent falls on the reagent strip (4) for detection;
s4, when the sliding plate (18) moves downwards to finish the dropping operation of the reagent to be detected, the connecting block (22) drives the second rack (38) to move downwards through the sliding rod (37), the second rack (38) is meshed with the gear (33) at the moment, the second rack (38) drives the gear (33), the rotating shaft (31) and the first code scanner (32) to rotate 90 degrees anticlockwise, the first code scanner (32) can scan the first bar code (5), the first code scanner (32) transmits code scanning information to the control terminal, the control terminal binds the corresponding first bar code (5) and the second bar code (20) with information, and when the gear (33) rotates 90 degrees anticlockwise, the gear (33) drives the first rack (35) to slide upwards and stretches the second tension spring (36);
s5, when the reagent to be detected in the liquid storage bag (19) is dripped completely and code scanning is completed, the first electric push rod (23) is started, an output shaft of the first electric push rod (23) drives the second rack (38), the sliding plate (18) and the sliding rod (37) to reset upwards through the connecting block (22), the sealing plate (10) closes the sample adding hole (2) again under the tension of the first tension spring (12) after losing the thrust of the trapezoidal block (24), the gear (33) reversely rotates under the tension of the second tension spring (36) after the second rack (38) is disengaged, and the first code scanner (32) is in a horizontal state again;
s6, with the continuous conveying of the metal conveying belt (15), after the metal conveying belt is conveyed for 15 minutes, the detection card main body (1) is located below the L-shaped frame (39), at the moment, the reaction of the test agent to be detected and the reagent strip (4) is finished, the camera (46) obtains a detection result through shooting the observation window (3), the second code scanner (45) scans the first bar code (5), the second code scanner (45) and the camera (46) transmit information to the control terminal, the control terminal binds the detection result with the corresponding first bar code (5) and the second bar code (20), the detection result of a user can be obtained, and the data confusion phenomenon occurring in the process of mass detection is avoided.
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|---|---|---|---|---|
| CN117705734A (en) * | 2024-02-06 | 2024-03-15 | 北京众驰伟业科技发展有限公司 | Testing device for detecting reagent strips |
| CN117705734B (en) * | 2024-02-06 | 2024-04-05 | 北京众驰伟业科技发展有限公司 | Testing device for detecting reagent strips |
| CN117871846A (en) * | 2024-03-12 | 2024-04-12 | 南京长健生物科技有限公司 | Handheld fluorescence immunoassay device |
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| CN115032404B (en) | 2023-05-23 |
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