CN115011416A - Bactericidal cleaning composition and preparation method thereof - Google Patents
Bactericidal cleaning composition and preparation method thereof Download PDFInfo
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- CN115011416A CN115011416A CN202210676653.6A CN202210676653A CN115011416A CN 115011416 A CN115011416 A CN 115011416A CN 202210676653 A CN202210676653 A CN 202210676653A CN 115011416 A CN115011416 A CN 115011416A
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- cleaning composition
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- betaine
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- 238000004140 cleaning Methods 0.000 title claims abstract description 119
- 239000000203 mixture Substances 0.000 title claims abstract description 84
- 238000002360 preparation method Methods 0.000 title abstract description 8
- 230000000844 anti-bacterial effect Effects 0.000 title description 35
- 230000002070 germicidal effect Effects 0.000 claims abstract description 73
- 239000003945 anionic surfactant Substances 0.000 claims abstract description 26
- 150000001412 amines Chemical class 0.000 claims abstract description 23
- 239000002280 amphoteric surfactant Substances 0.000 claims abstract description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 230000003115 biocidal effect Effects 0.000 claims abstract description 6
- 239000003139 biocide Substances 0.000 claims abstract description 6
- 239000011734 sodium Substances 0.000 claims description 16
- 125000000217 alkyl group Chemical group 0.000 claims description 11
- 125000004432 carbon atom Chemical group C* 0.000 claims description 11
- 229910052708 sodium Inorganic materials 0.000 claims description 10
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 9
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims description 9
- 230000002421 anti-septic effect Effects 0.000 claims description 8
- 229920006395 saturated elastomer Polymers 0.000 claims description 8
- 239000003960 organic solvent Substances 0.000 claims description 7
- 239000004711 α-olefin Substances 0.000 claims description 6
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical group CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 5
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 4
- 239000003755 preservative agent Substances 0.000 claims description 4
- DROMNWUQASBTFM-UHFFFAOYSA-N dinonyl benzene-1,2-dicarboxylate Chemical group CCCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCCC DROMNWUQASBTFM-UHFFFAOYSA-N 0.000 claims description 3
- 239000003205 fragrance Substances 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 230000002335 preservative effect Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 12
- 230000001954 sterilising effect Effects 0.000 abstract description 11
- 238000012360 testing method Methods 0.000 description 23
- 238000000034 method Methods 0.000 description 10
- 239000003899 bactericide agent Substances 0.000 description 9
- 230000000052 comparative effect Effects 0.000 description 9
- 239000000047 product Substances 0.000 description 8
- 239000004615 ingredient Substances 0.000 description 6
- 239000000523 sample Substances 0.000 description 6
- 238000004659 sterilization and disinfection Methods 0.000 description 6
- 239000003599 detergent Substances 0.000 description 5
- 238000004090 dissolution Methods 0.000 description 5
- 239000002244 precipitate Substances 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 239000004698 Polyethylene Substances 0.000 description 4
- 239000000975 dye Substances 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 238000011056 performance test Methods 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 description 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 2
- 239000004141 Sodium laurylsulphate Substances 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 229960003237 betaine Drugs 0.000 description 2
- 239000012459 cleaning agent Substances 0.000 description 2
- 230000008034 disappearance Effects 0.000 description 2
- 239000010721 machine oil Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- -1 sodium fatty alcohol Chemical class 0.000 description 2
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 2
- 229910021653 sulphate ion Inorganic materials 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 239000003517 fume Substances 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000012456 homogeneous solution Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/94—Mixtures with anionic, cationic or non-ionic compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
- C11D3/04—Water-soluble compounds
- C11D3/044—Hydroxides or bases
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
- C11D3/04—Water-soluble compounds
- C11D3/046—Salts
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
- C11D3/04—Water-soluble compounds
- C11D3/06—Phosphates, including polyphosphates
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/26—Organic compounds containing nitrogen
- C11D3/30—Amines; Substituted amines ; Quaternized amines
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/43—Solvents
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/12—Sulfonic acids or sulfuric acid esters; Salts thereof
- C11D1/14—Sulfonic acids or sulfuric acid esters; Salts thereof derived from aliphatic hydrocarbons or mono-alcohols
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/90—Betaines
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
Abstract
The invention provides a sterilizing and cleaning composition and a preparation method thereof. The germicidal cleaning composition comprises, based on 100% of its total weight: 0.1 to 15% by weight of an anionic surfactant; 0.3 to 5% by weight of an amine based biocide; 1 to 20% by weight of a betaine-type amphoteric surfactant; and the balance water. According to the technical scheme of the invention, each component in the sterilizing and cleaning composition is good in intersolubility, and good cleaning effect and sterilizing effect can be simultaneously realized, so that the sterilizing and cleaning composition is particularly suitable for cleaning the interior of a vehicle.
Description
Technical Field
The invention relates to the technical field of automobile product cleaning agents, particularly provides a sterilizing cleaning composition and a preparation method thereof, and more particularly provides a sterilizing cleaning composition suitable for being used as an automobile interior cleaning agent and a preparation method thereof.
Background
Currently, automotive product cleaners are widely used to clean interior vehicle surfaces. The automotive product cleaner has a good cleaning effect without damaging the interior trim surface of the vehicle. However, currently marketed automotive product cleaners generally have only one function of cleaning and are not effective in killing bacteria inside automobiles. The reason for this is that most of the currently used detergent products generally use an anionic surfactant as an alkali for cleaning, while the commonly used germicidal ingredients contain an active amine site, and these two chemicals react with each other to generate a precipitate, which results in the reduction or disappearance of the antibacterial performance of the germicidal ingredients. In order to provide both cleaning and bactericidal effects, a method of exerting cleaning action by replacing anionic surfactants with nonionic surfactants or amphoteric surfactants is generally used, but this results in a great reduction in cleaning effect of the detergent.
Therefore, it is of great significance to develop a detergent for automobile products that achieves both good cleaning and sterilization effects.
Disclosure of Invention
Starting from the technical problems set forth above, the present invention aims to provide a germicidal cleaning composition and a preparation method thereof, wherein the germicidal cleaning composition has good intersolubility of the components, can simultaneously achieve good cleaning effect and germicidal effect, and is particularly suitable for cleaning the interior of a vehicle.
The present inventors have made intensive studies and completed the present invention.
According to one aspect of the present invention, there is provided an antiseptic cleaning composition comprising, based on 100% of its total weight:
0.1 to 15% by weight of an anionic surfactant;
0.3 to 5% by weight of an amine based biocide;
1 to 20% by weight of a betaine-type amphoteric surfactant; and
the balance of water.
According to another aspect of the present invention, there is provided a method of preparing an antiseptic cleaning composition comprising uniformly mixing the components of the antiseptic cleaning composition described above.
The sterilization cleaning composition has the advantages that the components in the sterilization cleaning composition are good in intersolubility, good cleaning effect and sterilization effect can be achieved at the same time, and the sterilization cleaning composition is particularly suitable for cleaning the interior of a vehicle.
Detailed Description
It is to be understood that other various embodiments can be devised and modified by those skilled in the art in light of the teachings of this specification without departing from the scope or spirit of the disclosure. The following detailed description is, therefore, not to be taken in a limiting sense.
Unless otherwise indicated, all numbers expressing feature sizes, quantities, and physical and chemical characteristics used in the specification and claims are to be understood as being modified in all instances by the term "about". Accordingly, unless indicated to the contrary, the numerical references set forth in the foregoing specification and attached claims are approximations that can be suitably varied by those skilled in the art in seeking to obtain the desired properties utilizing the teachings disclosed herein. The use of numerical ranges by endpoints includes all numbers within that range and any range within that range, for example, 1 to 5 includes 1, 1.1, 1.3, 1.5, 2, 2.75, 3, 3.80, 4, and 5, and the like.
The inventors of the present application have found that by using a combination of an anionic surfactant, an amine bactericide and a betaine amphoteric surfactant in specific contents, a bactericidal cleaning composition can be provided which has good intersolubility of the respective components and can achieve both good cleaning effect and bactericidal effect.
According to one aspect of the present invention, there is provided a germicidal cleaning composition comprising, based on 100% of its total weight:
0.1 to 15% by weight of an anionic surfactant;
0.3 to 5% by weight of an amine based biocide;
1 to 20% by weight of a betaine-type amphoteric surfactant; and
the balance of water.
According to certain embodiments of the present invention, the germicidal cleaning composition includes an anionic surfactant as a cleaning ingredient. The specific type of anionic surfactant that can be employed in the present invention is not particularly limited, and may be appropriately selected from various types of anionic surfactants that are generally used for automobile interior cleaning. Preferably, the anionic surfactant is an alpha-olefin sulfonate. More preferably, the anionic surfactant is sodium alpha-olefin sulfonate. Preferably, the sodium alpha-olefin sulfonate comprises R 1 -CH＝CH-SO 3 -Na + And R 1 -CH(OH)-CH 2 -SO 3 -Na + Wherein R is 1 Is an alkyl group having 12 to 18 carbon atoms. According to certain embodiments of the present invention, the germicidal cleaning composition comprises from 0.1 wt% to 15 wt%, preferably from 0.1 wt% to 8 wt% of anionic surfactant, based on the total weight of the germicidal cleaning composition taken as 100%. Specific examples of the anionic surfactant that can be used in the present invention include: AOS (sodium alpha-olefin sulfonate) manufactured by PILOT Chemical Company; AES (sodium fatty alcohol polyoxyethylene ether sulphate), Sodium Lauryl Sulphate (SLS) and sodium fatty alcohol ether sulphate (SLES) manufactured by PILOT Chemical Company.
According to certain embodiments of the present invention, the germicidal cleaning composition includes an amine germicide as the germicidal ingredient. The specific type of amine-based bactericide that can be employed in the present invention is not particularly limited, and may be appropriately selected from various types of amine-based bactericides that are generally used for cleaning automobile interiors. Preferably, the amine fungicide has a structure represented by the following general formula (I):
wherein R is 2 Is a saturated straight chain alkyl group having 2 to 18 carbon atoms. According to certain embodiments of the present invention, the germicidal cleaning composition comprises 0.3 wt.% to 5 wt.%, preferably 0.3 wt.%, based on the total weight of the germicidal cleaning composition taken as 100%An amount% to 3 wt% of an amine based biocide. Specific examples of the amine-based bactericide which can be used in the present invention include: lonzakab 12 (which has a structure represented by the general formula (I) shown below, wherein R is R, produced by Longsha Chinese investment Ltd 2 A saturated straight chain alkyl group having 12 carbon atoms).
As described above, most of the current detergent products generally use an anionic surfactant as an alkali for cleaning, and on the other hand, the commonly used germicidal ingredients contain active amine sites, and these two chemicals react with each other to generate precipitates, which result in the reduction or disappearance of the antibacterial performance of the germicidal ingredients. The inventors of the present invention have found through intensive studies that by adding a specific content of a betaine-type amphoteric surfactant to an anionic surfactant and an amine type bactericidal component, the interaction between the anionic surfactant and the amine type bactericidal component can be reduced or avoided, and precipitation can be avoided, thereby achieving both good cleaning effect and bactericidal effect. Preferably, the betaine-type amphoteric surfactant has a structure represented by the following general formula (II):
wherein R is 3 Is a saturated straight-chain alkyl group having 9 to 20 carbon atoms, and n is an integer of 1 to 5. Preferably, the betaine-type amphoteric surfactant is cocamidopropyl betaine. According to certain embodiments of the present invention, the germicidal cleaning composition includes from 1 wt% to 20 wt%, preferably from 1 wt% to 10 wt%, of the betaine amphoteric surfactant, based on the total weight of the germicidal cleaning composition taken as 100%. Specific examples of the betaine-type amphoteric surfactant that can be used in the present invention include: cocoamidopropyl betaine (in its structure represented by the above general formula (II), R) produced by Zanzu technologies 3 Is a saturated straight-chain alkyl group having 12 carbon atoms, and n is 2).
In addition to the above-mentioned anionic surfactant, amine bactericide and betaine-type amphoteric surfactant, the germicidal cleaning composition according to the present invention may optionally further comprise one or more additives for achieving specific functions, as necessary. The additive is selected from one or more of preservatives, perfumes, dyes and the like. Preferably, the germicidal cleaning composition includes 0.4 wt% to 1.0 wt% preservative, based on the total weight of the germicidal cleaning composition taken as 100%. The germicidal cleaning composition includes 0.001 wt% to 0.1 wt% of a fragrance, based on the total weight of the germicidal cleaning composition taken as 100%. The germicidal cleaning composition includes 0.001 wt% to 0.1 wt% of a dye, based on the total weight of the germicidal cleaning composition taken as 100%.
In order to improve the compatibility between the components of the germicidal cleaning composition according to the present invention, it is preferable that the germicidal cleaning composition further comprises an organic solvent. Preferably, the organic solvent is dinonyl phthalate. Preferably, the germicidal cleaning composition includes 0.5 wt% to 5 wt% of an organic solvent, based on the total weight of the germicidal cleaning composition taken as 100%.
According to another aspect of the present invention, there is provided a method of preparing an antiseptic cleaning composition comprising uniformly mixing the components of the antiseptic cleaning composition described above. Preferably, the components of the germicidal cleaning composition described above are mixed and stirred at 200rpm for 10 minutes at room temperature to obtain a homogeneous solution.
The germicidal cleaning compositions according to the present invention are particularly useful for cleaning and germicidal cleaning of vehicle interiors. The method of applying the germicidal cleaning composition is not particularly limited, and the germicidal cleaning composition may be directly sprayed or brushed on parts such as interiors, panels, steering wheels, seats of automobiles, or the parts may be directly wiped with a soft cloth impregnated with the germicidal cleaning composition.
The following detailed description is intended to illustrate the disclosure by way of example and not by way of limitation.
Embodiment 1 is a germicidal cleaning composition comprising, based on its total weight of 100%:
0.1 to 15% by weight of an anionic surfactant;
0.3 to 5% by weight of an amine based biocide;
1 to 20% by weight of a betaine-type amphoteric surfactant; and
the balance of water.
Embodiment 2 is the germicidal cleaning composition of embodiment 1, wherein the anionic surfactant is an alpha-olefin sulfonate.
Embodiment 3 is the germicidal cleaning composition of embodiment 1, wherein the anionic surfactant is sodium alpha-olefinsulfonate.
Embodiment 4 is the germicidal cleaning composition of embodiment 3, wherein the sodium alpha-olefm sulfonate comprises R 1 -CH＝CH-SO 3 - Na + And R 1 -CH(OH)-CH 2 -SO 3 -Na + Wherein R is 1 Is an alkyl group having 12 to 18 carbon atoms.
Embodiment 5 is the germicidal cleaning composition of embodiment 1, wherein the amine germicide has a structure represented by the following general formula (I):
wherein R is 2 Is a saturated straight chain alkyl group having 2 to 18 carbon atoms.
Embodiment 6 is the germicidal cleaning composition of embodiment 1, wherein the betaine-type amphoteric surfactant has a structure represented by the following general formula (II):
wherein R is 3 Is a saturated straight-chain alkyl group having 9 to 20 carbon atoms, and n is an integer of 1 to 5.
Embodiment 7 is the germicidal cleaning composition of embodiment 1, wherein the betaine-type amphoteric surfactant is cocamidopropyl betaine.
Embodiment 8 is the germicidal cleaning composition of embodiment 1, further comprising one or more of preservatives, fragrances, and dyes.
Embodiment 9 is the germicidal cleaning composition of embodiment 1, further comprising an organic solvent.
Embodiment 10 is the germicidal cleaning composition of embodiment 9, wherein the organic solvent is dinonyl phthalate.
Embodiment 11 is a method of making a germicidal cleaning composition comprising uniformly mixing the components of the germicidal cleaning composition according to any one of embodiments 1-10.
The present invention will be described in more detail with reference to examples. It should be noted that the description and examples are intended to facilitate the understanding of the invention, and are not intended to limit the invention. The scope of the invention is to be determined by the claims appended hereto.
Examples
In the present invention, unless otherwise indicated, all reagents used were commercially available products and were used without further purification treatment.
Table 1 list of materials
Test method
Antibacterial rate
The antibacterial rate against staphylococcus aureus of each of the germicidal cleaning compositions prepared in the following examples and comparative examples was tested according to the method specified in the disinfection specification (2002 edition) as follows:
antibacterial property test
Preparation of the samples
Polyethylene sheets (PE sheets) (shanghai bin & hardware commerce limited) were cut to 5cm x 5cm and used for control samples and test samples, respectively.
As for the test samples, 9.5 to 10.5g of the detergent composition prepared according to the following examples or comparative examples was uniformly dropped on a PE plate using a dropper, and placed in a fume hood for 24 hours.
And (3) antibacterial property testing: 50ml of sterilized physiological saline was prepared. In a sterile room, at the side of flame, test strains (Staphylococcus aureus (Shanghai Industrial microbiology research institute)) were picked from the slant of the growing bacteria by inoculating loops, respectively, and placed in the sterilized normal saline. Shaking by hand for a while to disperse the bacteria sufficiently to obtain a bacterial suspension with a concentration of about 10 7 -10 8 One/ml.
PE plates prepared above were run in triplicate. Several milliliters of bacterial solution were dropped onto each sample to maintain the viable count at about 105. And (3) placing the sample into a sterile plate, culturing for 18-24 hours in a constant-temperature incubator at 36 +/-1 ℃, and counting viable bacteria. The above procedure was repeated with respect to the control sample.
The antibacterial ratio was calculated by the following formula:
the antibacterial ratio (%) [ (A-B)/A ]. times.100%
In the formula:
a: average viable count when control samples were kept at 36. + -. 1 ℃ for 24 hours
B: average viable count when the antimicrobial sample is maintained at 36 + -1 deg.C for 24 hours
The evaluation criteria for antibacterial properties were as follows:
TABLE 2
| Antibacterial rate | Level of antibacterial activity |
| More than 99 percent | Is excellent in |
| More than 90 percent and less than or equal to 99 percent | Good effect |
| More than 70 percent and less than or equal to 90 percent | Is preferably used |
| More than 50 percent and less than or equal to 70 percent | In general |
| Less than or equal to 50 percent | Basic ineffectiveness |
Cleaning performance
The cleaning performance of each of the germicidal cleaning compositions prepared in the following examples and comparative examples was tested by the method described in detail below.
Cleaning Performance test
1. Test piece
No. 45 steel sheet 3 pieces having dimensions of 75mm X26 mm X2 mm and having a finish of 6.
2. Oil stain: no. 20 machine oil.
3. Preparation and preservation of test specimens and test pieces
And (3) polishing the 3 test pieces by using No. 180 abrasive paper, cleaning the bright test pieces by using gasoline and ethanol in sequence, drying the test pieces by using hot air, and placing the test pieces in a dryer for later use.
4. Test method
The test pieces to be used are weighed on a balance to the nearest 0.1 mg. The weighed test pieces were coated with 20 # machine oil, and placed in a desiccator for 30min before weighing. Stirring (25r/s), heating the test solution to 70 +/-2 ℃, taking 3 test pieces coated with oil and weighed out from the dryer, immersing the test pieces in a beaker filled with the sample, and taking out the test pieces after washing for 5 min.
The test piece was further rinsed 10 times in 400ml of distilled water at normal temperature, immediately dried with hot air from a blower after being taken out, and weighed after being placed in a dryer for 30 min.
The cleaning performance was calculated by the following formula:
the cleaning ratio (%) - (M1-M2)/(M1-M0) × 100%
In the formula:
m1-mass of mechanical oil coupon;
m2-quality of test piece after washing;
m0-quality of test piece to be used.
The evaluation criteria for cleaning performance were as follows:
TABLE 3
| Cleaning rate | Cleaning level |
| Greater than or equal to 70 percent | Is excellent in |
| Less than 70 percent | In general |
Solubility in water
The solubility of each of the germicidal cleaning compositions prepared in the following examples and comparative examples was tested by the method described in detail below.
And (3) solubility testing step: 100ml of sample was taken and placed in an oven at 50 ℃ for 2 weeks. The precipitate was filtered and placed in an oven at 50 ℃ for 1 week before the filtered precipitate was weighed. The above steps were repeated three times.
However, the dissolution rate was calculated by the following formula:
the dissolution rate (%) [ (a-B)/a ] × 100%
In the formula:
a: sample weight
B: weight of precipitate
The evaluation criteria for dissolution properties were as follows:
TABLE 4
| Dissolution rate | Level of dissolution |
| Greater than or equal to 70 percent | Is excellent in |
| Less than 70 percent | In general |
Example 1
0.1g of sodium alpha-olefinsulfonate, 0.3g of the amine bactericide Lonzabac12 and 3g of cocamidopropyl betaine and 96.6g of water were uniformly mixed to obtain a bactericidal cleaning composition 1. The individual components and their amounts used to prepare germicidal cleaning composition 1 are shown in table 5 below.
The antibacterial rate, cleaning performance and solubility of the resulting germicidal cleaning composition 1 were tested according to the method for testing antibacterial rate, cleaning performance and solubility described in detail above and the results thereof are shown in table 5 below.
Examples 2 to 7 and comparative examples 1 to 6
Germicidal cleaning compositions 2-7 and comparative germicidal cleaning compositions 1-6 were prepared in a similar manner to example 1, except that the individual components and their specific amounts were varied. The individual components and their amounts used to prepare germicidal cleaning compositions 2-7 and comparative germicidal cleaning compositions 1-6 are shown in tables 5 and 6, respectively, below.
The antibacterial rate, cleaning performance and solubility of the resulting germicidal cleaning compositions 2-7 and comparative germicidal cleaning compositions 1-6 were tested according to the method for testing antibacterial rate, cleaning performance and solubility described in detail above and the results are shown in tables 5 and 6 below, respectively.
Table 5 individual components of germicidal cleaning compositions according to examples 1-7 and their specific amounts and performance test results
TABLE 6 Bactericidal cleaning compositions according to comparative examples 1-6, the respective components and their specific contents, and the results of the performance tests
As is apparent from the results shown in table 5, when a combination of a specific anionic surfactant, an amine bactericide, and a betaine-type amphoteric surfactant at specific contents is employed within the scope of the present invention, excellent intersolubility between the respective components in the germicidal cleaning composition can be achieved, while excellent cleaning effect and germicidal effect can be achieved.
In addition, from the results shown in table 6, it is understood that when the contents of the anionic surfactant, the amine bactericide, and the betaine-type amphoteric surfactant are out of the range of the present invention, excellent mutual solubility between the anionic surfactant and the amine bactericide cannot be achieved, and further, excellent cleaning effect and bactericidal effect cannot be obtained at the same time.
Although specific embodiments have been illustrated and described herein, it will be appreciated by those of ordinary skill in the art that a variety of alternate and/or equivalent implementations may be substituted for the specific embodiments shown and described without departing from the scope of the present invention. This application is intended to cover any adaptations or variations of the specific embodiments discussed in the present disclosure. Accordingly, it is intended that this invention be limited only by the claims and the equivalents thereof.
It will be understood by those skilled in the art that various changes and modifications may be made without departing from the scope of the invention. Such modifications and variations are intended to fall within the scope of the invention as defined in the appended claims.
Claims (11)
1. An antiseptic cleaning composition comprising, based on 100% of its total weight:
0.1 to 15% by weight of an anionic surfactant;
0.3 to 5% by weight of an amine based biocide;
1 to 20% by weight of a betaine-type amphoteric surfactant; and
the balance of water.
2. The germicidal cleaning composition of claim 1, wherein the anionic surfactant is an alpha-olefin sulfonate.
3. The germicidal cleaning composition of claim 1, wherein the anionic surfactant is sodium alpha-olefm sulfonate.
4. The germicidal cleaning composition of claim 3, wherein the sodium alpha-olefm sulfonate comprises R 1 -CH＝CH-SO 3 - Na + And R 1 -CH(OH)-CH 2 -SO 3 - Na + Wherein R is 1 Is an alkyl group having 12 to 18 carbon atoms.
5. The germicidal cleaning composition of claim 1 wherein the amine germicide has a structure represented by the following general formula (I):
wherein R is 2 Is a saturated straight chain alkyl group having 2 to 18 carbon atoms.
6. The germicidal cleaning composition according to claim 1, wherein the betaine-type amphoteric surfactant has a structure represented by the following general formula (II):
wherein R is 3 Is a saturated straight-chain alkyl group having 9 to 20 carbon atoms, and n is an integer of 1 to 5.
7. The germicidal cleaning composition of claim 1, wherein the betaine-type amphoteric surfactant is cocamidopropyl betaine.
8. The germicidal cleaning composition of claim 1, further comprising one or more of a preservative, a fragrance, and a dye.
9. The germicidal cleaning composition of claim 1, further comprising an organic solvent.
10. The germicidal cleaning composition of claim 9, wherein the organic solvent is dinonyl phthalate.
11. A method of making an antiseptic cleaning composition comprising uniformly mixing the components of the antiseptic cleaning composition of any of claims 1-10.
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Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5576284A (en) * | 1994-09-26 | 1996-11-19 | Henkel Kommanditgesellschaft Auf Aktien | Disinfecting cleanser for hard surfaces |
| US5739168A (en) * | 1993-08-19 | 1998-04-14 | Kao Corporation | Germicidal-disinfectant detergent composition |
| US6030936A (en) * | 1997-01-06 | 2000-02-29 | Reckitt & Colman Inc. | Blooming type disinfecting cleaning compositions |
| JP2002212007A (en) * | 2001-01-18 | 2002-07-31 | Asahi Denka Kogyo Kk | Bactericidal composition |
| US20060247150A1 (en) * | 2000-06-29 | 2006-11-02 | Molinaro Katherine J | Stable antimicrobial compositions including spore, bacteria, fungi, and/or enzyme |
| WO2012148004A1 (en) * | 2011-04-28 | 2012-11-01 | 上野製薬株式会社 | Bactericide composition and bactericidal cleaning composition |
| CN104135858A (en) * | 2011-12-29 | 2014-11-05 | 拜奥特罗尔有限公司 | Anti-microbial composition |
| CN104884044A (en) * | 2012-12-21 | 2015-09-02 | 利拉伐控股有限公司 | Germicidal compositions comprising carboxylic acid mixture and use as topical disinfectants |
| US20170347644A1 (en) * | 2016-06-02 | 2017-12-07 | Ecolab Usa Inc. | Quaternary disinfectant composition with anionic scale inhibiting agent |
| US20190233773A1 (en) * | 2018-01-26 | 2019-08-01 | Ecolab Usa Inc. | Solidifying liquid amine oxide, betaine, and/or sultaine surfactants with a carrier |
| CN110392528A (en) * | 2017-03-01 | 2019-10-29 | 埃科莱布美国股份有限公司 | The dangerous disinfectant and fungicide of sucking is reduced by heavy polymer |
| CN110655993A (en) * | 2018-06-29 | 2020-01-07 | 3M创新有限公司 | Detergent composition having long-term antibacterial properties |
-
2022
- 2022-06-15 CN CN202210676653.6A patent/CN115011416B/en active Active
Patent Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5739168A (en) * | 1993-08-19 | 1998-04-14 | Kao Corporation | Germicidal-disinfectant detergent composition |
| US5576284A (en) * | 1994-09-26 | 1996-11-19 | Henkel Kommanditgesellschaft Auf Aktien | Disinfecting cleanser for hard surfaces |
| US6030936A (en) * | 1997-01-06 | 2000-02-29 | Reckitt & Colman Inc. | Blooming type disinfecting cleaning compositions |
| US20060247150A1 (en) * | 2000-06-29 | 2006-11-02 | Molinaro Katherine J | Stable antimicrobial compositions including spore, bacteria, fungi, and/or enzyme |
| JP2002212007A (en) * | 2001-01-18 | 2002-07-31 | Asahi Denka Kogyo Kk | Bactericidal composition |
| WO2012148004A1 (en) * | 2011-04-28 | 2012-11-01 | 上野製薬株式会社 | Bactericide composition and bactericidal cleaning composition |
| CN104135858A (en) * | 2011-12-29 | 2014-11-05 | 拜奥特罗尔有限公司 | Anti-microbial composition |
| CN104884044A (en) * | 2012-12-21 | 2015-09-02 | 利拉伐控股有限公司 | Germicidal compositions comprising carboxylic acid mixture and use as topical disinfectants |
| US20170347644A1 (en) * | 2016-06-02 | 2017-12-07 | Ecolab Usa Inc. | Quaternary disinfectant composition with anionic scale inhibiting agent |
| CN109152371A (en) * | 2016-06-02 | 2019-01-04 | 埃科莱布美国股份有限公司 | Quaternary ammonium antiseptics composition with anionic antisludging agent |
| CN110392528A (en) * | 2017-03-01 | 2019-10-29 | 埃科莱布美国股份有限公司 | The dangerous disinfectant and fungicide of sucking is reduced by heavy polymer |
| US20190233773A1 (en) * | 2018-01-26 | 2019-08-01 | Ecolab Usa Inc. | Solidifying liquid amine oxide, betaine, and/or sultaine surfactants with a carrier |
| CN110655993A (en) * | 2018-06-29 | 2020-01-07 | 3M创新有限公司 | Detergent composition having long-term antibacterial properties |
Non-Patent Citations (3)
| Title |
|---|
| 张晓冬等: "工业水处理常用杀菌剂的调查研究", 广东化工, vol. 41, no. 6, pages 141 - 142 * |
| 林显佳等: "含十二烷基二亚丙三胺抗菌洗手液的制备及抗菌性能探究", 日用化学工业, vol. 52, no. 4, pages 376 - 382 * |
| 马业萍等: "杀菌剂在家用洗涤剂中的应用及研究进展", 中国洗涤用品工业 消毒杀菌技术特刊, no. 2020, pages 235 - 140 * |
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