CN115011416B - Sterilization cleaning composition and preparation method thereof - Google Patents
Sterilization cleaning composition and preparation method thereof Download PDFInfo
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- CN115011416B CN115011416B CN202210676653.6A CN202210676653A CN115011416B CN 115011416 B CN115011416 B CN 115011416B CN 202210676653 A CN202210676653 A CN 202210676653A CN 115011416 B CN115011416 B CN 115011416B
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- 238000004140 cleaning Methods 0.000 title claims abstract description 114
- 239000000203 mixture Substances 0.000 title claims abstract description 79
- 230000001954 sterilising effect Effects 0.000 title abstract description 22
- 238000002360 preparation method Methods 0.000 title abstract description 8
- 238000004659 sterilization and disinfection Methods 0.000 title description 3
- 230000003115 biocidal effect Effects 0.000 claims abstract description 35
- 239000003945 anionic surfactant Substances 0.000 claims abstract description 25
- 150000001412 amines Chemical class 0.000 claims abstract description 23
- 230000002070 germicidal effect Effects 0.000 claims abstract description 20
- 239000002280 amphoteric surfactant Substances 0.000 claims abstract description 19
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims abstract description 15
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims abstract description 15
- 229960003237 betaine Drugs 0.000 claims abstract description 15
- 239000003139 biocide Substances 0.000 claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 230000000844 anti-bacterial effect Effects 0.000 claims description 49
- 239000011734 sodium Substances 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 12
- 125000000217 alkyl group Chemical group 0.000 claims description 11
- 125000004432 carbon atom Chemical group C* 0.000 claims description 11
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims description 11
- 239000004711 α-olefin Substances 0.000 claims description 11
- 239000003899 bactericide agent Substances 0.000 claims description 10
- 229910052708 sodium Inorganic materials 0.000 claims description 10
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 9
- 229920006395 saturated elastomer Polymers 0.000 claims description 8
- 239000003960 organic solvent Substances 0.000 claims description 7
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical group CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 5
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 4
- 239000003755 preservative agent Substances 0.000 claims description 4
- 230000002335 preservative effect Effects 0.000 claims description 4
- DROMNWUQASBTFM-UHFFFAOYSA-N dinonyl benzene-1,2-dicarboxylate Chemical group CCCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCCC DROMNWUQASBTFM-UHFFFAOYSA-N 0.000 claims description 3
- 239000003205 fragrance Substances 0.000 claims description 3
- 230000002421 anti-septic effect Effects 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 11
- 238000012360 testing method Methods 0.000 description 20
- 230000000052 comparative effect Effects 0.000 description 9
- 239000000047 product Substances 0.000 description 8
- 239000000523 sample Substances 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 238000004090 dissolution Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 239000004698 Polyethylene Substances 0.000 description 4
- 239000003599 detergent Substances 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 239000000975 dye Substances 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 238000011056 performance test Methods 0.000 description 3
- 239000002244 precipitate Substances 0.000 description 3
- 238000001556 precipitation Methods 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 230000008034 disappearance Effects 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- -1 sodium fatty alcohol Chemical class 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 244000137852 Petrea volubilis Species 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 238000005282 brightening Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 239000003517 fume Substances 0.000 description 1
- 239000012456 homogeneous solution Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000010721 machine oil Substances 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 239000003206 sterilizing agent Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/94—Mixtures with anionic, cationic or non-ionic compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
- C11D3/04—Water-soluble compounds
- C11D3/044—Hydroxides or bases
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
- C11D3/04—Water-soluble compounds
- C11D3/046—Salts
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
- C11D3/04—Water-soluble compounds
- C11D3/06—Phosphates, including polyphosphates
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/26—Organic compounds containing nitrogen
- C11D3/30—Amines; Substituted amines ; Quaternized amines
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/43—Solvents
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/12—Sulfonic acids or sulfuric acid esters; Salts thereof
- C11D1/14—Sulfonic acids or sulfuric acid esters; Salts thereof derived from aliphatic hydrocarbons or mono-alcohols
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/90—Betaines
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
Abstract
The application provides a sterilizing cleaning composition and a preparation method thereof. The germicidal cleaning composition comprises, based on 100% of its total weight: 0.1 to 15 wt% of an anionic surfactant; 0.3 to 5 wt% of an amine biocide; 1 to 20% by weight of a betaine type amphoteric surfactant; and the balance water. The components in the sterilizing and cleaning composition disclosed by the technical scheme of the application have good intersolubility, can realize good cleaning effect and sterilizing effect at the same time, and are especially suitable for cleaning the interior of a vehicle.
Description
Technical Field
The application relates to the technical field of automotive product cleaners, in particular to a sterilizing and cleaning composition and a preparation method thereof, and more particularly relates to a sterilizing and cleaning composition suitable for being used as an automotive interior cleaner and a preparation method thereof.
Background
Currently, automotive product cleaners are widely used to clean interior surfaces of vehicles. The automobile product cleaning agent has good cleaning effect and does not damage the surface of the vehicle interior. However, currently marketed automotive product cleaners generally have only one cleaning function and are not effective in killing bacteria within the interior of an automobile. The reason for this is that most of the detergent products currently usually use anionic surfactants as the base for cleaning, and on the other hand, the sterilizing component usually used contains active amine sites, and these two chemical substances react with each other to cause precipitation, resulting in a decrease or disappearance of the antibacterial property of the sterilizing component. In order to provide both cleaning and sterilizing effects, a method of substituting a nonionic surfactant or an amphoteric surfactant for an anionic surfactant is generally used to exert the cleaning effect, but this results in a significant reduction in the cleaning effect of the cleaner.
Therefore, it is of great importance to develop a detergent for automobile products which achieves both good cleaning and sterilizing effects.
Disclosure of Invention
Starting from the technical problems set forth above, the application aims to provide a sterilizing cleaning composition and a preparation method thereof, wherein each component in the sterilizing cleaning composition has good intersolubility, can realize good cleaning effect and sterilizing effect at the same time, and is particularly suitable for cleaning the interior of a vehicle.
The present inventors have conducted intensive studies to complete the present application.
According to one aspect of the present application, there is provided a biocidal cleaning composition comprising, based on 100% of its total weight:
0.1 to 15 wt% of an anionic surfactant;
0.3 to 5 wt% of an amine biocide;
1 to 20% by weight of a betaine type amphoteric surfactant; and
the balance of water.
According to another aspect of the present application, there is provided a method of preparing a biocidal cleaning composition comprising uniformly mixing the components of the biocidal cleaning composition described above.
The bactericidal cleaning composition has the advantages that the components in the bactericidal cleaning composition have good intersolubility, can realize good cleaning effect and bactericidal effect at the same time, and is especially suitable for cleaning the interior of a vehicle.
Detailed Description
It is to be understood that other various embodiments can be devised and modifications to the embodiments by those skilled in the art based on the teachings herein without departing from the scope or spirit of this disclosure. The following detailed description is, therefore, not to be taken in a limiting sense.
All numbers expressing feature sizes, amounts, and physical and chemical characteristics used in the specification and claims are to be understood as being modified in all instances by the term "about" unless otherwise indicated. Accordingly, unless indicated to the contrary, the numerical parameters set forth in the foregoing specification and attached claims are approximations that can be varied appropriately by those skilled in the art utilizing the desired properties sought to be obtained by the teachings disclosed herein. The use of numerical ranges by endpoints includes all numbers subsumed within that range and any range within that range, e.g., 1 to 5 includes 1, 1.1, 1.3, 1.5, 2, 2.75, 3, 3.80, 4, 5, and the like.
The inventors of the present application have found that by using a combination of anionic surfactant, amine bactericide and betaine type amphoteric surfactant in specific amounts, it is possible to provide a bactericidal cleaning composition which is excellent in miscibility of the respective components and can achieve both excellent cleaning effect and bactericidal effect.
According to one aspect of the present application, there is provided a biocidal cleaning composition comprising, based on 100% of its total weight:
0.1 to 15 wt% of an anionic surfactant;
0.3 to 5 wt% of an amine biocide;
1 to 20% by weight of a betaine type amphoteric surfactant; and
the balance of water.
According to certain embodiments of the present application, the germicidal cleaning composition comprises an anionic surfactant as a cleaning ingredient. The specific type of the anionic surfactant that can be used in the present application is not particularly limited, and can be activated at various anionic surfaces commonly used for cleaning of automobile interiorsThe sex agent is appropriately selected. Preferably, the anionic surfactant is an alpha-olefin sulfonate. More preferably, the anionic surfactant is sodium alpha-olefin sulfonate. Preferably, the sodium alpha-olefin sulfonate comprises R 1 -CH＝CH-SO 3 -Na + And R is 1 -CH(OH)-CH 2 -SO 3 -Na + Wherein R is 1 Is an alkyl group having 12 to 18 carbon atoms. According to certain embodiments of the present application, the biocidal cleaning composition comprises 0.1 wt.% to 15 wt.%, preferably 0.1 wt.% to 8 wt.% anionic surfactant, based on 100 wt.% of the total biocidal cleaning composition. Specific examples of the anionic surfactant which can be used in the present application include: AOS (sodium alpha-olefin sulfonate) manufactured by PILOT Chemical Company company; AES (sodium fatty alcohol polyoxyethylene ether sulfate), sodium dodecyl sulfate (SLS), and sodium fatty alcohol ether sulfate (SLES) produced by PILOT Chemical Company.
According to certain embodiments of the present application, the biocidal cleaning composition comprises an amine biocide as a biocidal ingredient. The specific type of the amine-based bactericide that can be employed in the present application is not particularly limited, and may be appropriately selected among various amine-based bactericides commonly used for cleaning of automobile interiors. Preferably, the amine germicides have a structure represented by the following general formula (I):
wherein R is 2 Is a saturated straight chain alkyl group having 2 to 18 carbon atoms. According to certain embodiments of the present application, the biocidal cleaning composition comprises 0.3 to 5 wt%, preferably 0.3 to 3 wt%, amine biocide based on the total weight of the biocidal cleaning composition taken as 100%. Specific examples of amine bactericides that can be used in the present application include: lonzabac12 (which has the structure represented by the above general formula (I), wherein R 2 Is a saturated straight chain alkyl group having 12 carbon atoms).
As mentioned above, most of the current detergent products generally use anionic surfactants as the base for cleaning, and on the other hand, the sterilizing component generally used contains active amine sites, and these two chemical substances react with each other to cause precipitation, resulting in degradation or disappearance of the antibacterial property of the sterilizing component. The inventors of the present application have found through intensive studies that by adding a specific content of betaine type amphoteric surfactant to anionic surfactant and amine type sterilizing ingredients, the effect between anionic surfactant and amine type sterilizing agent can be reduced or avoided, and precipitation is avoided, thereby achieving both good cleaning effect and sterilizing effect. Preferably, the betaine type amphoteric surfactant has a structure represented by the following general formula (II):
wherein R is 3 Is a saturated straight-chain alkyl group having 9-20 carbon atoms, and n is an integer of 1 to 5. Preferably, the betaine type amphoteric surfactant is cocamidopropyl betaine. According to certain embodiments of the present application, the biocidal cleaning composition comprises 1 wt% to 20 wt%, preferably 1 wt% to 10 wt% betaine type amphoteric surfactant, based on the total weight of the biocidal cleaning composition taken as 100%. Specific examples of betaine-type amphoteric surfactants that can be used in the present application include: cocamidopropyl betaine (in its structure represented by the above general formula (II)), R, produced by Zan science and technology Co 3 Is a saturated straight chain alkyl group having 12 carbon atoms, and n is 2).
In addition to the above-mentioned anionic surfactants, amine bactericides and betaine-type amphoteric surfactants, the bactericidal cleaning composition according to the application may optionally contain one or more additives for achieving specific functions as required. The additive is selected from one or more of preservative, perfume and dye. Preferably, the biocidal cleaning composition comprises 0.4 wt% to 1.0 wt% preservative based on 100% total weight of the biocidal cleaning composition. The biocidal cleaning composition comprises 0.001 wt% to 0.1 wt% fragrance based on 100% total weight of the biocidal cleaning composition. The biocidal cleaning composition comprises 0.001 wt% to 0.1 wt% dye based on 100% total weight of the biocidal cleaning composition.
In order to improve the compatibility between the respective components in the sterilizing cleaning composition according to the present application, it is preferable that the sterilizing cleaning composition further comprises an organic solvent. Preferably, the organic solvent is dinonyl phthalate. Preferably, the biocidal cleaning composition comprises 0.5 to 5 wt% organic solvent based on 100% total weight of the biocidal cleaning composition.
According to another aspect of the present application, there is provided a method of preparing a biocidal cleaning composition comprising uniformly mixing the components of the biocidal cleaning composition described above. Preferably, the components of the bactericidal cleaning composition described above are mixed and stirred at 200rpm for 10 minutes at room temperature to obtain a homogeneous solution.
The bactericidal cleaning composition according to the application is particularly suitable for cleaning and sterilizing the interior of a vehicle. The method of applying the bactericidal cleaning composition is not particularly limited, and the bactericidal cleaning composition may be directly sprayed or brushed onto parts such as an interior trim, a panel, a steering wheel, a seat, etc. of an automobile, or the above parts may be directly rubbed with a soft cloth impregnated with the bactericidal cleaning composition.
The following detailed description is intended to illustrate the disclosure by way of example and not by way of limitation.
Embodiment 1 is a germicidal cleaning composition comprising, based on 100% of its total weight:
0.1 to 15 wt% of an anionic surfactant;
0.3 to 5 wt% of an amine biocide;
1 to 20% by weight of a betaine type amphoteric surfactant; and
the balance of water.
Embodiment 2 is the germicidal cleaning composition of embodiment 1 wherein the anionic surfactant is an alpha-olefin sulfonate.
Embodiment 3 is the germicidal cleaning composition of embodiment 1 wherein the anionic surfactant is sodium alpha-olefin sulfonate.
Embodiment 4 is the germicidal cleaning composition of embodiment 3, wherein the sodium alpha-olefin sulfonate comprises R 1 -CH＝CH-SO 3 - Na + And R is 1 -CH(OH)-CH 2 -SO 3 -Na + Wherein R is 1 Is an alkyl group having 12 to 18 carbon atoms.
Embodiment 5 is the germicidal cleaning composition according to embodiment 1, wherein the amine germicide has a structure represented by the following general formula (I):
wherein R is 2 Is a saturated straight chain alkyl group having 2 to 18 carbon atoms.
Embodiment 6 is the germicidal cleaning composition according to embodiment 1, wherein the betaine-type amphoteric surfactant has a structure represented by the following general formula (II):
wherein R is 3 Is a saturated straight-chain alkyl group having 9-20 carbon atoms, and n is an integer of 1 to 5.
Embodiment 7 is the germicidal cleaning composition of embodiment 1 wherein the betaine type amphoteric surfactant is cocamidopropyl betaine.
Embodiment 8 is the germicidal cleaning composition of embodiment 1 further comprising one or more of a preservative, a fragrance, and a dye.
Embodiment 9 is the germicidal cleaning composition of embodiment 1, further comprising an organic solvent.
Embodiment 10 is the germicidal cleaning composition of embodiment 9 wherein the organic solvent is dinonyl phthalate.
Embodiment 11 is a method of preparing a biocidal cleaning composition comprising uniformly mixing the components of the biocidal cleaning composition according to any one of embodiments 1-10.
The present application will be described in more detail with reference to examples. It should be noted that the description and examples are intended to facilitate an understanding of the application and are not intended to limit the application. The scope of the application is defined by the appended claims.
Examples
In the present application, unless otherwise indicated, the reagents employed were all commercially available products and were used directly without further purification treatment.
Table 1 list of raw materials
Test method
Antibacterial rate
The antibacterial activity against staphylococcus aureus of each of the bactericidal cleaning compositions prepared in the following examples and comparative examples was tested according to the method specified in the disinfection technical specification (2002 edition) as follows:
antibacterial test
Preparation of the samples
Polyethylene sheets (PE sheets) (Shanghai, available from feihu trade company) were cut 5cm by 5cm and used for control and test samples, respectively.
For the test samples, the detergent compositions prepared according to the following examples or comparative examples were uniformly dropped onto the PE plate with a dropper 9.5-10.5g, and placed in a fume hood for 24 hours.
Antibacterial testing step: 50ml of sterilized physiological saline was prepared. In the aseptic chamber, the test strains (staphylococcus aureus (Shanghai industrial microbiology institute)) were picked up from the slant of the long bacteria by an inoculating loop, respectively, beside the flame, and put into the above sterilized physiological saline. Shaking for a while by hand to fully disperse bacteria to obtain bacterial suspension with a concentration of about 10 7 -10 8 And each milliliter.
The PE plates prepared above were run in triplicate. A plurality of milliliters of bacterial liquid was added dropwise to each sample, and the number of viable bacteria was kept at about 105. The test sample is placed in a sterile plate, and after being cultured in a constant temperature incubator at 36+/-1 ℃ for 18-24 hours, living bacteria are counted. The above procedure was repeated for the control samples.
The antibacterial ratio was calculated by the following formula:
antibacterial ratio (%) = [ (a-B)/a ] ×100%
Wherein:
a: average viable count when the control sample was maintained at 36.+ -. 1 ℃ for 24 hours
B: average viable count when the antimicrobial sample was maintained at 36.+ -. 1 ℃ for 24 hours
The evaluation criteria for the antibacterial property were as follows:
TABLE 2
| Antibacterial rate | Antibacterial level |
| More than 99 percent | Excellent and excellent properties |
| More than 90% and less than or equal to 99% | Good quality |
| More than 70% and less than or equal to 90% | Preferably, it is |
| More than 50% and less than or equal to 70% | In general |
| Less than or equal to 50% | Is basically ineffective |
Cleaning performance
The cleaning performance of each of the bactericidal cleaning compositions prepared in the following examples and comparative examples was tested by the method described in detail below.
Cleaning performance test
1. Test piece
And the number 45 steel sheet 3 with the size of 75mm multiplied by 26mm multiplied by 2mm has the finish degree of 6.
2. Greasy dirt: no. 20 machine oil.
3. Preparation and preservation of test specimens and test specimens
Polishing 3 test pieces with No. 180 sand paper, cleaning with gasoline and ethanol after brightening, drying with hot air, and placing in a dryer for use.
4. Test method
The test piece to be used was weighed on a balance to the nearest 0.1mg. The weighed test piece was coated with No. 20 mechanical oil, left in a desiccator for 30min, and then weighed. Stirring (25 r/s) was started, the test solution was heated to (70.+ -. 2) C, 3 pieces of the oiled and weighed test pieces were taken out from the dryer, immersed in a beaker containing the sample, and after washing for 5min, taken out.
And then the test piece is put into 400ml of distilled water at normal temperature for 10 times, taken out, immediately dried by hot air of a blower, placed in a dryer for 30min and weighed.
The cleaning performance was calculated by the following formula:
cleaning rate (%) = (M1-M2)/(M1-M0) ×100%
Wherein:
m1-mass of the test piece with mechanical oil;
m2-quality of the test piece after cleaning;
m0-mass of test piece to be used.
The evaluation criteria for cleaning performance were as follows:
TABLE 3 Table 3
| Cleaning rate | Cleaning level |
| More than or equal to 70 percent | Excellent and excellent properties |
| Less than 70% | In general |
Solubility of
The solubility of each of the bactericidal cleaning compositions prepared in the following examples and comparative examples was tested by the method described in detail below.
A solubility testing step: 100ml of the sample was taken and placed in an oven at 50℃for 2 weeks. The precipitate was filtered and placed in an oven at 50 ℃ for 1 week before weighing the filtered precipitate. The above steps were repeated three times.
However, the dissolution rate was calculated by the following formula:
dissolution rate (%) = [ (a-B)/a ] ×100%
Wherein:
a: sample weight
B: weight of precipitate
The evaluation criteria for dissolution performance were as follows:
TABLE 4 Table 4
| Dissolution rate | Dissolution level |
| More than or equal to 70 percent | Excellent and excellent properties |
| Less than 70% | In general |
Example 1
0.1g of sodium alpha-olefin sulfonate, 0.3g of an amine bactericide Lonzabac12 and 3g of cocamidopropyl betaine and 96.6g of water were uniformly mixed to obtain a bactericidal cleaning composition 1. The individual components and amounts used to prepare the germicidal cleaning composition 1 are shown in table 5 below.
The antibacterial rate, cleaning performance and solubility of the resulting antibacterial cleaning composition 1 were tested according to the methods for testing antibacterial rate, cleaning performance and solubility described in detail above and the results thereof are shown in table 5 below.
Examples 2 to 7 and comparative examples 1 to 6
The biocidal cleaning compositions 2-7 and comparative biocidal cleaning compositions 1-6 were prepared in a similar manner to example 1 except that the individual components and their specific contents were varied. The individual components used to prepare the biocidal cleaning compositions 2-7 and comparative biocidal cleaning compositions 1-6, and their contents, are shown in tables 5 and 6, respectively, below.
The resulting antibacterial cleaning compositions 2 to 7 and comparative antibacterial cleaning compositions 1 to 6 were tested for antibacterial rate, cleaning performance and solubility according to the methods for testing antibacterial rate, cleaning performance and solubility described in detail above and the results thereof are shown in tables 5 and 6 below, respectively.
TABLE 5 Each component of the antibacterial cleaning compositions according to examples 1 to 7 and its specific content and results of performance test
TABLE 6 Each component of the antibacterial cleaning composition according to comparative examples 1 to 6 and its specific content and results of performance test
From the results shown in table 5, it is apparent that when a combination of specific anionic surfactant, amine bactericide and betaine type amphoteric surfactant is used in specific amounts within the scope of the present application, excellent miscibility between the respective components in the bactericidal cleaning composition can be achieved while excellent cleaning effect and bactericidal effect can be achieved.
Further, as is clear from the results shown in table 6, when the contents of the anionic surfactant, the amine bactericide and the betaine type amphoteric surfactant are out of the range of the present application, excellent mutual solubility between the anionic surfactant and the amine bactericide cannot be achieved, and furthermore, excellent cleaning effect and sterilizing effect cannot be obtained at the same time.
Although specific embodiments of the application have been illustrated and described herein, it will be appreciated by those of ordinary skill in the art that a wide variety of alternate and/or equivalent implementations may be substituted for the specific embodiments shown and described without departing from the scope of the present application. This application is intended to encompass any modifications or alterations to the specific embodiments discussed in this application. Therefore, it is intended that this application be limited only by the claims and the equivalents thereof.
It will be understood by those skilled in the art that various modifications and changes may be made without departing from the scope of the present application. Such modifications and variations are intended to fall within the scope of the application as defined in the appended claims.
Claims (8)
1. A germicidal cleaning composition comprising, based on 100% of its total weight:
0.1 to 15 wt% of an anionic surfactant;
0.3 to 5 wt% of an amine biocide;
1 to 20% by weight of a betaine type amphoteric surfactant; and
the balance of water, wherein
The anionic surfactant is alpha-olefin sulfonate;
the amine bactericide has a structure represented by the following general formula (I):
wherein R is 2 Is a saturated straight chain alkyl group having 2 to 18 carbon atoms; and is also provided with
The betaine type amphoteric surfactant has a structure represented by the following general formula (II):
wherein R is 3 Is a saturated straight-chain alkyl group having 9-20 carbon atoms, and n is an integer of 1 to 5.
2. The antiseptic cleaning composition of claim 1, wherein the anionic surfactant is sodium alpha-olefin sulfonate.
3. The bactericidal cleaning composition of claim 2 wherein the sodium alpha-olefin sulfonate comprises R 1 -CH＝CH-SO 3 - Na + And R is 1 -CH(OH)-CH 2 -SO 3 - Na + Wherein R is 1 Is an alkyl group having 12 to 18 carbon atoms.
4. The bactericidal cleaning composition of claim 1 wherein the betaine type amphoteric surfactant is cocamidopropyl betaine.
5. The antiseptic cleaning composition of claim 1, further comprising one or more of a preservative, a fragrance, and a dye.
6. The germicidal cleaning composition of claim 1 further comprising an organic solvent.
7. The germicidal cleaning composition of claim 6 wherein the organic solvent is dinonyl phthalate.
8. A method of preparing a germicidal cleaning composition comprising homogeneously mixing the components of the germicidal cleaning composition as defined in any one of claims 1-7.
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